LOCUS       DBERCW010000001       129250 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.001, whole genome shotgun sequence.
ACCESSION   DBERCW010000001 DBERCW010000000
VERSION     DBERCW010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 129250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 129250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..129250
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.001"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(21..956)
                     /gene="birA"
                     /locus_tag="ACL72M_000001"
     CDS             complement(21..956)
                     /gene="birA"
                     /locus_tag="ACL72M_000001"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGS0715211.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(953..1813)
                     /locus_tag="ACL72M_000002"
     CDS             complement(953..1813)
                     /locus_tag="ACL72M_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS0715212.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRAGQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1921..4083
                     /locus_tag="ACL72M_000003"
     CDS             1921..4083
                     /locus_tag="ACL72M_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGS0715213.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4175..5434
                     /locus_tag="ACL72M_000004"
     CDS             4175..5434
                     /locus_tag="ACL72M_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0715214.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5448..6314
                     /locus_tag="ACL72M_000005"
     CDS             5448..6314
                     /locus_tag="ACL72M_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0715215.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6328..7161
                     /locus_tag="ACL72M_000006"
     CDS             6328..7161
                     /locus_tag="ACL72M_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0715216.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7168..7335
                     /locus_tag="ACL72M_000007"
     CDS             7168..7335
                     /locus_tag="ACL72M_000007"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715217.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKVKLTWFEEI
                     FEEYKKSSWNL"
     gene            7519..8961
                     /gene="gtfA"
                     /locus_tag="ACL72M_000008"
     CDS             7519..8961
                     /gene="gtfA"
                     /locus_tag="ACL72M_000008"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGS0715218.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9099..10292
                     /locus_tag="ACL72M_000009"
     CDS             9099..10292
                     /locus_tag="ACL72M_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGS0715219.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVFCLYIIS
                     LIFTGDMKSILQKMGEHSMLLLFLGYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10978..12957
                     /locus_tag="ACL72M_000010"
     CDS             10978..12957
                     /locus_tag="ACL72M_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0715220.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKTSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13024..14520
                     /locus_tag="ACL72M_000011"
     CDS             13024..14520
                     /locus_tag="ACL72M_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715221.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14520..15446
                     /gene="oppC"
                     /locus_tag="ACL72M_000012"
     CDS             14520..15446
                     /gene="oppC"
                     /locus_tag="ACL72M_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGS0715222.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15455..16522
                     /locus_tag="ACL72M_000013"
     CDS             15455..16522
                     /locus_tag="ACL72M_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715223.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16533..17459
                     /locus_tag="ACL72M_000014"
     CDS             16533..17459
                     /locus_tag="ACL72M_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0715224.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            17949..18886
                     /locus_tag="ACL72M_000015"
                     /pseudo
     CDS             17949..18886
                     /locus_tag="ACL72M_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            18898..19791
                     /locus_tag="ACL72M_000016"
     CDS             18898..19791
                     /locus_tag="ACL72M_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715225.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLTGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            19804..20607
                     /locus_tag="ACL72M_000017"
     CDS             19804..20607
                     /locus_tag="ACL72M_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715226.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20640..21350)
                     /gene="treR"
                     /locus_tag="ACL72M_000018"
     CDS             complement(20640..21350)
                     /gene="treR"
                     /locus_tag="ACL72M_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGS0715227.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIREQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21535..23502
                     /gene="treP"
                     /locus_tag="ACL72M_000019"
     CDS             21535..23502
                     /gene="treP"
                     /locus_tag="ACL72M_000019"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGS0715228.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            23680..25305
                     /gene="treC"
                     /locus_tag="ACL72M_000020"
     CDS             23680..25305
                     /gene="treC"
                     /locus_tag="ACL72M_000020"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGS0715229.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25561..25809
                     /locus_tag="ACL72M_000021"
     CDS             25561..25809
                     /locus_tag="ACL72M_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGS0715230.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26016..26810
                     /gene="racE"
                     /locus_tag="ACL72M_000022"
     CDS             26016..26810
                     /gene="racE"
                     /locus_tag="ACL72M_000022"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGS0715231.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26807..27778
                     /locus_tag="ACL72M_000023"
     CDS             26807..27778
                     /locus_tag="ACL72M_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGS0715232.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27754..28275
                     /locus_tag="ACL72M_000024"
     CDS             27754..28275
                     /locus_tag="ACL72M_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS0715233.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28272..28733
                     /gene="cbpB"
                     /locus_tag="ACL72M_000025"
     CDS             28272..28733
                     /gene="cbpB"
                     /locus_tag="ACL72M_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGS0715234.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28730..29464
                     /gene="xerD"
                     /locus_tag="ACL72M_000026"
     CDS             28730..29464
                     /gene="xerD"
                     /locus_tag="ACL72M_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGS0715235.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29464..30192
                     /locus_tag="ACL72M_000027"
     CDS             29464..30192
                     /locus_tag="ACL72M_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGS0715236.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30211..30780
                     /gene="scpB"
                     /locus_tag="ACL72M_000028"
     CDS             30211..30780
                     /gene="scpB"
                     /locus_tag="ACL72M_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGS0715237.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30767..31489
                     /locus_tag="ACL72M_000029"
     CDS             30767..31489
                     /locus_tag="ACL72M_000029"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS0715238.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31489..31731
                     /gene="yidD"
                     /locus_tag="ACL72M_000030"
     CDS             31489..31731
                     /gene="yidD"
                     /locus_tag="ACL72M_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGS0715239.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(31956..32921)
                     /locus_tag="ACL72M_000031"
     CDS             complement(31956..32921)
                     /locus_tag="ACL72M_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0715240.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33017..33769)
                     /locus_tag="ACL72M_000032"
     CDS             complement(33017..33769)
                     /locus_tag="ACL72M_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715241.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33766..34722)
                     /locus_tag="ACL72M_000033"
     CDS             complement(33766..34722)
                     /locus_tag="ACL72M_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGS0715242.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34712..35671)
                     /locus_tag="ACL72M_000034"
     CDS             complement(34712..35671)
                     /locus_tag="ACL72M_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715243.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(35968..36078)
                     /locus_tag="ACL72M_000035"
     CDS             complement(35968..36078)
                     /locus_tag="ACL72M_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGS0715244.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(36094..36795)
                     /gene="galE"
                     /locus_tag="ACL72M_000036"
     CDS             complement(36094..36795)
                     /gene="galE"
                     /locus_tag="ACL72M_000036"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS0715245.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37196..38260
                     /gene="pepA"
                     /locus_tag="ACL72M_000037"
     CDS             37196..38260
                     /gene="pepA"
                     /locus_tag="ACL72M_000037"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGS0715246.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38282..38578
                     /locus_tag="ACL72M_000038"
     CDS             38282..38578
                     /locus_tag="ACL72M_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS0715247.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            39260..39703
                     /locus_tag="ACL72M_000039"
     CDS             39260..39703
                     /locus_tag="ACL72M_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS0715248.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            39707..40471
                     /locus_tag="ACL72M_000040"
     CDS             39707..40471
                     /locus_tag="ACL72M_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGS0715249.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVIPKVEDLTNRGKF"
     gene            40486..41214
                     /locus_tag="ACL72M_000041"
     CDS             40486..41214
                     /locus_tag="ACL72M_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0715250.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIENGEFMVLVGPSGSGKTTMI
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLTTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41207..42727
                     /locus_tag="ACL72M_000042"
     CDS             41207..42727
                     /locus_tag="ACL72M_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGS0715251.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43072..43878
                     /gene="pnuC"
                     /locus_tag="ACL72M_000043"
     CDS             43072..43878
                     /gene="pnuC"
                     /locus_tag="ACL72M_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGS0715252.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44044..44580)
                     /gene="sczA"
                     /locus_tag="ACL72M_000044"
     CDS             complement(44044..44580)
                     /gene="sczA"
                     /locus_tag="ACL72M_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGS0715253.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            44713..45603
                     /gene="czcD"
                     /locus_tag="ACL72M_000045"
     CDS             44713..45603
                     /gene="czcD"
                     /locus_tag="ACL72M_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGS0715254.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            45847..46200
                     /gene="nmlR"
                     /locus_tag="ACL72M_000046"
     CDS             45847..46200
                     /gene="nmlR"
                     /locus_tag="ACL72M_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGS0715255.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46201..47238
                     /locus_tag="ACL72M_000047"
     CDS             46201..47238
                     /locus_tag="ACL72M_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGS0715256.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIIIE"
     gene            complement(47285..48292)
                     /gene="galR"
                     /locus_tag="ACL72M_000048"
     CDS             complement(47285..48292)
                     /gene="galR"
                     /locus_tag="ACL72M_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGS0715257.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGINLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48457..49635
                     /locus_tag="ACL72M_000049"
     CDS             48457..49635
                     /locus_tag="ACL72M_000049"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGS0715258.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49654..51135
                     /locus_tag="ACL72M_000050"
     CDS             49654..51135
                     /locus_tag="ACL72M_000050"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS0715259.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            51205..51609
                     /locus_tag="ACL72M_000051"
     CDS             51205..51609
                     /locus_tag="ACL72M_000051"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGS0715260.1"
                     /translation="MKDFHFDAISAFESYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            51790..52554
                     /locus_tag="ACL72M_000052"
     CDS             51790..52554
                     /locus_tag="ACL72M_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGS0715261.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            52551..53012
                     /locus_tag="ACL72M_000053"
     CDS             52551..53012
                     /locus_tag="ACL72M_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGS0715262.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(53063..54325)
                     /locus_tag="ACL72M_000054"
     CDS             complement(53063..54325)
                     /locus_tag="ACL72M_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGS0715263.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGNGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(54325..54906)
                     /locus_tag="ACL72M_000055"
     CDS             complement(54325..54906)
                     /locus_tag="ACL72M_000055"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGS0715264.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(55306..55401)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(55784..56023)
                     /locus_tag="ACL72M_000056"
     CDS             complement(55784..56023)
                     /locus_tag="ACL72M_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGS0715265.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(56071..56166)
                     /locus_tag="ACL72M_000057"
                     /pseudo
     CDS             complement(56071..56166)
                     /locus_tag="ACL72M_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
     gene            complement(56178..57005)
                     /locus_tag="ACL72M_000058"
     CDS             complement(56178..57005)
                     /locus_tag="ACL72M_000058"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGS0715266.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            57139..57595
                     /locus_tag="ACL72M_000059"
                     /pseudo
     CDS             57139..57595
                     /locus_tag="ACL72M_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            57592..58122
                     /locus_tag="ACL72M_000060"
     CDS             57592..58122
                     /locus_tag="ACL72M_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGS0715267.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            58250..59995
                     /locus_tag="ACL72M_000061"
     CDS             58250..59995
                     /locus_tag="ACL72M_000061"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715268.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            59985..61736
                     /locus_tag="ACL72M_000062"
     CDS             59985..61736
                     /locus_tag="ACL72M_000062"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715269.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            61909..62601
                     /locus_tag="ACL72M_000063"
     CDS             61909..62601
                     /locus_tag="ACL72M_000063"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS0715270.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            62644..63870
                     /locus_tag="ACL72M_000064"
     CDS             62644..63870
                     /locus_tag="ACL72M_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGS0715271.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            65001..67160
                     /gene="pfbA"
                     /locus_tag="ACL72M_000065"
     CDS             65001..67160
                     /gene="pfbA"
                     /locus_tag="ACL72M_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGS0715272.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            67144..67440
                     /locus_tag="ACL72M_000066"
     CDS             67144..67440
                     /locus_tag="ACL72M_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715273.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            67612..67995
                     /locus_tag="ACL72M_000067"
     CDS             67612..67995
                     /locus_tag="ACL72M_000067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715274.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDPIGTNSVLNKKIILQKIR
                     KLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELIK
                     MRFNSSAIDPIYGKKDDASIVVIDV"
     gene            68053..68694
                     /locus_tag="ACL72M_000068"
     CDS             68053..68694
                     /locus_tag="ACL72M_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGS0715275.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QIIQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            68707..70182
                     /gene="galT"
                     /locus_tag="ACL72M_000069"
     CDS             68707..70182
                     /gene="galT"
                     /locus_tag="ACL72M_000069"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS0715276.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKFGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            70195..71175
                     /gene="galE"
                     /locus_tag="ACL72M_000070"
     CDS             70195..71175
                     /gene="galE"
                     /locus_tag="ACL72M_000070"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS0715277.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGLPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            71385..72044
                     /locus_tag="ACL72M_000071"
     CDS             71385..72044
                     /locus_tag="ACL72M_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGS0715278.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            72069..73136
                     /locus_tag="ACL72M_000072"
     CDS             72069..73136
                     /locus_tag="ACL72M_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0715279.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELASKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWGVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            73239..74249
                     /locus_tag="ACL72M_000073"
     CDS             73239..74249
                     /locus_tag="ACL72M_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715280.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            74261..75952
                     /locus_tag="ACL72M_000074"
     CDS             74261..75952
                     /locus_tag="ACL72M_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715281.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            75955..76665
                     /locus_tag="ACL72M_000075"
     CDS             75955..76665
                     /locus_tag="ACL72M_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGS0715282.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            76761..77129
                     /locus_tag="ACL72M_000076"
     CDS             76761..77129
                     /locus_tag="ACL72M_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715283.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            77237..78238
                     /locus_tag="ACL72M_000077"
     CDS             77237..78238
                     /locus_tag="ACL72M_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0715284.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    78450..78679
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            78845..79096
                     /locus_tag="ACL72M_000078"
     CDS             78845..79096
                     /locus_tag="ACL72M_000078"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715285.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKYCFEVVDRTDEVS
                     SKHCFEVADRTDEVSNHTYGKATLTRFEEIFEEYKGVSK"
     gene            79469..80830
                     /gene="trpE"
                     /locus_tag="ACL72M_000079"
     CDS             79469..80830
                     /gene="trpE"
                     /locus_tag="ACL72M_000079"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGS0715286.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNSFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGVTDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            80827..81393
                     /locus_tag="ACL72M_000080"
     CDS             80827..81393
                     /locus_tag="ACL72M_000080"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGS0715287.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            81404..82408
                     /gene="trpD"
                     /locus_tag="ACL72M_000081"
     CDS             81404..82408
                     /gene="trpD"
                     /locus_tag="ACL72M_000081"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGS0715288.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDVRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            82405..83172
                     /gene="trpC"
                     /locus_tag="ACL72M_000082"
     CDS             82405..83172
                     /gene="trpC"
                     /locus_tag="ACL72M_000082"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGS0715289.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLNYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            83159..83758
                     /locus_tag="ACL72M_000083"
     CDS             83159..83758
                     /locus_tag="ACL72M_000083"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGS0715290.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            83736..84959
                     /gene="trpB"
                     /locus_tag="ACL72M_000084"
     CDS             83736..84959
                     /gene="trpB"
                     /locus_tag="ACL72M_000084"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGS0715291.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            84952..85728
                     /gene="trpA"
                     /locus_tag="ACL72M_000085"
     CDS             84952..85728
                     /gene="trpA"
                     /locus_tag="ACL72M_000085"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGS0715292.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(85700..85801)
                     /locus_tag="ACL72M_000086"
                     /pseudo
     CDS             complement(85700..85801)
                     /locus_tag="ACL72M_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            86030..86761
                     /locus_tag="ACL72M_000087"
     CDS             86030..86761
                     /locus_tag="ACL72M_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715293.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            86776..87927
                     /locus_tag="ACL72M_000088"
     CDS             86776..87927
                     /locus_tag="ACL72M_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0715294.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(87979..88638)
                     /locus_tag="ACL72M_000089"
     CDS             complement(87979..88638)
                     /locus_tag="ACL72M_000089"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGS0715295.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWKLLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTCHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            88708..89154
                     /locus_tag="ACL72M_000090"
     CDS             88708..89154
                     /locus_tag="ACL72M_000090"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0715296.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSILKLE"
     gene            complement(89382..90560)
                     /locus_tag="ACL72M_000091"
     CDS             complement(89382..90560)
                     /locus_tag="ACL72M_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS0715297.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            90840..92102
                     /locus_tag="ACL72M_000092"
     CDS             90840..92102
                     /locus_tag="ACL72M_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0715298.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            92105..93001
                     /locus_tag="ACL72M_000093"
     CDS             92105..93001
                     /locus_tag="ACL72M_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGS0715299.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            93016..93333
                     /locus_tag="ACL72M_000094"
     CDS             93016..93333
                     /locus_tag="ACL72M_000094"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0715300.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            93350..93667
                     /locus_tag="ACL72M_000095"
     CDS             93350..93667
                     /locus_tag="ACL72M_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0715301.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            93677..95032
                     /locus_tag="ACL72M_000096"
     CDS             93677..95032
                     /locus_tag="ACL72M_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0715302.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLNQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWHAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            95355..96830
                     /locus_tag="ACL72M_000097"
     CDS             95355..96830
                     /locus_tag="ACL72M_000097"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGS0715303.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVNFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            96827..97675
                     /locus_tag="ACL72M_000098"
     CDS             96827..97675
                     /locus_tag="ACL72M_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGS0715304.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDNFEDPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTGLDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            97690..98460
                     /locus_tag="ACL72M_000099"
     CDS             97690..98460
                     /locus_tag="ACL72M_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGS0715305.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            99263..99502
                     /locus_tag="ACL72M_000100"
     CDS             99263..99502
                     /locus_tag="ACL72M_000100"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0715306.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            complement(99612..99827)
                     /locus_tag="ACL72M_000101"
     CDS             complement(99612..99827)
                     /locus_tag="ACL72M_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS0715307.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGAVEGVKNMLSGDDK"
     gene            complement(99858..100466)
                     /locus_tag="ACL72M_000102"
     CDS             complement(99858..100466)
                     /locus_tag="ACL72M_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0715308.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(100505..100675)
                     /locus_tag="ACL72M_000103"
     CDS             complement(100505..100675)
                     /locus_tag="ACL72M_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGS0715309.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(100687..101253)
                     /gene="amaP"
                     /locus_tag="ACL72M_000104"
     CDS             complement(100687..101253)
                     /gene="amaP"
                     /locus_tag="ACL72M_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGS0715310.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(101337..101501)
                     /locus_tag="ACL72M_000105"
     CDS             complement(101337..101501)
                     /locus_tag="ACL72M_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS0715311.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            101944..103425
                     /gene="mgaSpn"
                     /locus_tag="ACL72M_000106"
                     /gene_synonym="mgrA"
     CDS             101944..103425
                     /gene="mgaSpn"
                     /locus_tag="ACL72M_000106"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGS0715312.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            103787..104788
                     /locus_tag="ACL72M_000107"
     CDS             103787..104788
                     /locus_tag="ACL72M_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0715313.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     KVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            104939..105856
                     /locus_tag="ACL72M_000108"
     CDS             104939..105856
                     /locus_tag="ACL72M_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715314.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAVRLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            105867..106757
                     /locus_tag="ACL72M_000109"
     CDS             105867..106757
                     /locus_tag="ACL72M_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0715315.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            106786..108402
                     /locus_tag="ACL72M_000110"
     CDS             106786..108402
                     /locus_tag="ACL72M_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0715316.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            108412..109731
                     /locus_tag="ACL72M_000111"
     CDS             108412..109731
                     /locus_tag="ACL72M_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS0715317.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            110242..110622
                     /locus_tag="ACL72M_000112"
     CDS             110242..110622
                     /locus_tag="ACL72M_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715318.1"
                     /translation="MRIQMRLSKEARVVLEELKLEYLKKGEDKTSGVIVDEIFKHFSS
                     NFQKVDWKSVQSAPKFNEILADYTSVNPTTLNLSNSTISTMSYIRDHFNYILDMKRTV
                     YRSFIIRLVLKAYKLEKEGTDIYL"
     gene            110735..110977
                     /locus_tag="ACL72M_000113"
     CDS             110735..110977
                     /locus_tag="ACL72M_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715319.1"
                     /translation="MKINEYLWRTSCLILLIIMSFFAGFGAKLEFTSYNPFLSVKFGL
                     VVALTVFVVQLLAILPAMVKRGNKNENVESNNSCEE"
     gene            110940..112331
                     /locus_tag="ACL72M_000114"
     CDS             110940..112331
                     /locus_tag="ACL72M_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGS0715320.1"
                     /translation="MRMLNQTIRVKSKYPYLIRPRNIKIVRLFIQIFVFLLLISSWIA
                     IIPFIARLVFSMFFISLLFFVEKFFRSNFIAKLRNKLNIREALFYMLISLNLYDELDN
                     EVVDTAVLYFDVENNKVVVCAPLFGNRYLKTLKNLEEYLCPTLGLSLLSKKEEIDKIV
                     YVLGQKEEIEQYVFNSNTLTREFFKDIPSSIIKLSNTQKFSLKSNTNLGIYGRTGTGK
                     TIALQWYLFNALAKGCGIADNTYLGIVDGKAADLYRIGELLHEELGEQVAVGSSPQML
                     AQLSRKFIENMDARFKIIKQNSSLNADIYELDELGLVPNFLFVDELASIRDSCGSTKQ
                     GRETWNEILQNLGLIARKGRQAGCHLVLSTQDPNAENIPVELRNQISAVLYLGAPGAD
                     RLKMAFSMCELENVPTVSDRKGEALFYADGLNTVEPVLTIVPFVDLKTKKEFLNVVRN
                     ILPTNDGLPPLAK"
     gene            112587..113006
                     /locus_tag="ACL72M_000115"
     CDS             112587..113006
                     /locus_tag="ACL72M_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715321.1"
                     /translation="MVYNMTDTNIKIGLLDLEMSQFDIPKKVVILSVRVNNKYKEVNG
                     ENVKTDEVSKITSAVLDADKVKVLTEMGISTDDLKAINLEIIGNLDKIAKLAQNDALL
                     NVPVELIRPKVRLAWNMARNNWSGVKIVCEDIKVLGE"
     gene            113011..114030
                     /locus_tag="ACL72M_000116"
     CDS             113011..114030
                     /locus_tag="ACL72M_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGS0715322.1"
                     /translation="MNTVRIDYFAVTVKNISPEKVLTDILLIPLENFTLNDWGINKYK
                     QHYSCSEIKVYFNADRLSMGVFIELKGQGCRQYEEFLNSNENNWIALISRLYHHNANF
                     TRLDIAHDIFDGSLDVQRIYDYCKKGLCISKAKHFEYHEKSVLDSGERVGETVAIGSR
                     GNQQWCIYNKRMEQLGKQELVEVSSWTRAELRCWQEKANIIAEQLYLKRPLSSIYFEA
                     INGHYRFIRPNAIDSNRWRRKKVEWWVNYLGTENQTVLSITRAKTTLRESEVWTEKQV
                     AKTLAKVYIAKYQAYDVQKAEDYIQNLLKEGLSKLTDNDEKDIEQYIREQNSSQLWGT
                     DGRSD"
     gene            114034..114216
                     /locus_tag="ACL72M_000117"
     CDS             114034..114216
                     /locus_tag="ACL72M_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGS0715323.1"
                     /translation="MADTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            114218..115345
                     /locus_tag="ACL72M_000118"
     CDS             114218..115345
                     /locus_tag="ACL72M_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0715324.1"
                     /translation="MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(115428..115500)
                     /locus_tag="ACL72M_000119"
     tRNA            complement(115428..115500)
                     /locus_tag="ACL72M_000119"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(115465..115467),aa:Lys,seq:ctt)
     gene            complement(115765..117036)
                     /locus_tag="ACL72M_000120"
     CDS             complement(115765..117036)
                     /locus_tag="ACL72M_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGS0715325.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            117306..117506
                     /locus_tag="ACL72M_000121"
     CDS             117306..117506
                     /locus_tag="ACL72M_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715326.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            117710..117889
                     /locus_tag="ACL72M_000122"
     CDS             117710..117889
                     /locus_tag="ACL72M_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715327.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            118026..118205
                     /locus_tag="ACL72M_000123"
     CDS             118026..118205
                     /locus_tag="ACL72M_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGS0715328.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            118242..118694
                     /locus_tag="ACL72M_000124"
     CDS             118242..118694
                     /locus_tag="ACL72M_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGS0715329.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            118985..119455
                     /locus_tag="ACL72M_000125"
     CDS             118985..119455
                     /locus_tag="ACL72M_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGS0715330.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            119474..120562
                     /locus_tag="ACL72M_000126"
     CDS             119474..120562
                     /locus_tag="ACL72M_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGS0715331.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            120543..120971
                     /locus_tag="ACL72M_000127"
     CDS             120543..120971
                     /locus_tag="ACL72M_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0715332.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            121109..122059
                     /gene="prmA"
                     /locus_tag="ACL72M_000128"
     CDS             121109..122059
                     /gene="prmA"
                     /locus_tag="ACL72M_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGS0715333.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            122061..122804
                     /locus_tag="ACL72M_000129"
     CDS             122061..122804
                     /locus_tag="ACL72M_000129"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGS0715334.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            122815..124611
                     /gene="pepF"
                     /locus_tag="ACL72M_000130"
     CDS             122815..124611
                     /gene="pepF"
                     /locus_tag="ACL72M_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS0715335.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(124671..125348)
                     /locus_tag="ACL72M_000131"
     CDS             complement(124671..125348)
                     /locus_tag="ACL72M_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGS0715336.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQKKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEQGKEF
                     LEKEWGI"
     gene            125595..126365
                     /locus_tag="ACL72M_000132"
     CDS             125595..126365
                     /locus_tag="ACL72M_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715337.1"
                     /translation="MLYLLGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDFLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            126358..127122
                     /locus_tag="ACL72M_000133"
     CDS             126358..127122
                     /locus_tag="ACL72M_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715338.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            127547..128338
                     /locus_tag="ACL72M_000134"
     CDS             127547..128338
                     /locus_tag="ACL72M_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGS0715339.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLVFTSF
                     AKEIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSILFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            128449..129117
                     /locus_tag="ACL72M_000135"
     CDS             128449..129117
                     /locus_tag="ACL72M_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS0715340.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFANKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLIIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT        39338 a        22263 c        28038 g        39611 t
ORIGIN      
        1 tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc actatttagc
       61 cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga gatgtcttta
      121 gcaagtccct tgtagtcttt ttgctgtagt gtgaaagtga cttcttttcc tagaatgaat
      181 gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa agcacgccag
      241 atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa gctggcagct
      301 ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac tccaataatg
      361 atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat tcctccaatt
      421 ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat taaagttagg
      481 ttcttaatag ctttgtagac agctccagct acaagtagtg tgtaggatgg taatttgtca
      541 taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg tgagtagaag
      601 gaacgttgaa aacgtcctcg gcctgctgtt tgataggaag ctagatagag ggtatttgct
      661 tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt ttcgggttta
      721 aagctgactt taattggaag attttcttct agaatctctg gaagaataag gtcaccattc
      781 attagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg ttctagtcgc
      841 ttgatagctt tccaaattga tgttcggctt agggatagtt tttctgcgat tttttctccg
      901 ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga tttcataatg
      961 ttgcctttct cactagttgg tattgagagt attcttttct tgtatgactt ggagtctgat
     1021 taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct accgagtatg
     1081 caattacctt gatggactct tgggtatttt cgagaagttg tccagctcgg tgcattcgaa
     1141 cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg cttgataagt
     1201 agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat tgaggatagt
     1261 ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa atattctttt
     1321 ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt tgtcccatga
     1381 tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca atgtctgaga
     1441 tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag gattgatcag
     1501 aaatttggga aagagcaaaa taatcagggg ctttccctcc agtgattcct aaccagtagt
     1561 aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt tttaatagaa
     1621 agaaatctcc ttcttttaaa tcaacaattt tacccttgta atgaaatttt ccttgtcctt
     1681 tagtaatgta atgtagaacg tatgtatcac gaatggctgg accaaaagag taattaggtg
     1741 tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc tggtattctg
     1801 aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga gacatttttc
     1861 tattttggaa agcgatttca ggtgataaaa tataatcaat aaagtgatga ggtgaagtaa
     1921 atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct aagtttgatt
     1981 attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat taagaactat
     2041 aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc aacggctact
     2101 aatcgaacct ttagtttaga tactcaacgt caaatttttg gacaacatgg cttaggagat
     2161 tttaggaaac caaccataca ggttcagcat aatgtaactg aagtaacaga ctttcgattt
     2221 gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc tccacatagc
     2281 atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca acttagtctg
     2341 actttgtatt atactacttt taataatgat gcgactattg ctagctacag taaattagat
     2401 aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc tgattttcca
     2461 gctgcagatt atgaaatagc aactctgcag ggtgcttatg ctcgtgaaaa gactgttaga
     2521 cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc ttctggtcat
     2581 gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc tgggaatgtg
     2641 tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa aaatcaattg
     2701 aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa gttagcccct
     2761 gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg attaactggt
     2821 attagtcatg aaagtcagaa ttttgtactg aagcacatta tgctaagtga attttctaaa
     2881 aaagaacgtc caattctaat caataactgg gaagctactt actttgactt tcagagagaa
     2941 aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt tgtattagat
     3001 gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg ggttgttaat
     3061 gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga aagaggtttg
     3121 cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt gtatcgtcaa
     3181 catcctgact gggctattca ggttcctgat tatgagcata cttattctcg gaatcaatta
     3241 gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt agatcaactc
     3301 ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat cactaagcta
     3361 gggaatggat taacttatct agagacacag atgcaatctc atcagtacat gctggggctt
     3421 tacgaactcg tttcttatct gacagagaag cacagccata ttctctttga gtcctgctct
     3481 ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt ctgggctagt
     3541 gataatactg atgccattgc acgtttacca attcaatacg gttcatccta tctctatcca
     3601 accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg acgaatgaca
     3661 ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga gcttgatttg
     3721 acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt gtataaagaa
     3781 ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga tactgcatcc
     3841 aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta cgttcgcgtt
     3901 ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga tgaagaggga
     3961 ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat gtatgcgggc
     4021 ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt tagaaaacta
     4081 tgatatgtac tgaccccaaa agttagattt attctgtcta acttttgggg tgcagttcaa
     4141 taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa aaatcggact
     4201 tcttgcaact acaggtttag ctttgtttgg gctcggcgct tgctccaact atggtaaatc
     4261 tgcggatggc acagtgacca tcgagtattt caaccagaaa aaagaaatga ccaaaacctt
     4321 ggaagaaatc actcgtgatt ttgagaagga aaaccctaag atcaaggtca aagtcgtcaa
     4381 tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg tgcctgatgt
     4441 ggtcaatatt tacccacagt ccatcgaact gcaagaatgg gcaaaagcag gtgtttttga
     4501 agatttgagc aacaaagact acctgaaacg cgtgaaaaat gcctacgctg aaaaatatgc
     4561 tgtaaacgaa aaagtttata acgttccttt tacagctaat gcttatggaa tttactacaa
     4621 caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg aatttgaaca
     4681 gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag gtgcagatgc
     4741 ctggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg gaggaaaaga
     4801 agcaaatcaa taccttcgtt attctcaacc aaatgccatt aaattgtcgg atccgattat
     4861 gaaagatgac atcaaggtca tggacatcct tcgcatcaat ggctctaagc aaaagaactg
     4921 ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg tcctcatgac
     4981 accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact ttaagattgg
     5041 gaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg cgggagactt
     5101 ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct ttgtggaata
     5161 tatgacccgt ccagaagtca tgcaaaaata ctacgatgtg gacggatctc caacagcgat
     5221 cgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg aatatgcctt
     5281 tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag acttccatac
     5341 cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg atttgaatgc
     5401 cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg aaaaaagtat
     5461 tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa gcaattttct
     5521 tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca ggattgactt
     5581 acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat ccaaaattca
     5641 tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt gagattgcac
     5701 tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc ttcttccgtg
     5761 cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc ttcaagcaag
     5821 tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt ctccaaacca
     5881 gtcttttagg gactaagtgg ggagcaatct ttgcggctgt ctttgtcctt ctttggcaag
     5941 gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca actgagatta
     6001 cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac attgaattgc
     6061 cttacttgct accaagtgtc tctatggtct ttatcctagc cctaaaaggt gggctgactg
     6121 cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca acctcacttg
     6181 ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc aatgccattg
     6241 ccgtaatctt gttcctctta attgtagtga tttcgatcat ccaattgaga gtatctaaga
     6301 aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc cctgattggc
     6361 aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct tgctaccctc
     6421 tttagttcct tcaaacccac taaggatatt gtagataatt tctttggctt tccaaccaac
     6481 ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta ttattggaac
     6541 tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc tatggcagcc
     6601 tactccatcg ctcgcaatat gagtaaaaga aaagtcttta ccatcatgta taccctctta
     6661 atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt tatgatgagt
     6721 aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta tgcgattcca
     6781 cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag tctggatgaa
     6841 gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat cttcccaatg
     6901 atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg gaatgacttc
     6961 atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc tttgttccaa
     7021 tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc ttacgtggtc
     7081 ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat ttcaggaatg
     7141 agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag gaagctagcc
     7201 gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt cagtaaccat
     7261 acctacggta aggtgaagct gacgtggttt gaagagattt tcgaagagta taagaagagc
     7321 tcatggaatc tatagtcttt gacacagagg aagagttcag cttgttgata attctatgta
     7381 gaaaacaaga aagtagtact ttgtttatca cagtctatat tagtacgagt ttgatgataa
     7441 atagagattt aaaatgaatt tgatttacga agccagatca tatgagactt ggcttcaatt
     7501 agaaaaagga gagtaatgat gccaattcaa aataaaacca tgttgattac ctattctgat
     7561 agccttggaa ataatcttaa agacttatat gataatttgg aagagcattt tggagatgct
     7621 attggaggag ttcacctttt accatttttc ccatcaacag gtgatcgtgg atttgcgcca
     7681 gttgactacg acgaagtgga ctcagctttt ggtgattggg aggatgttaa gcgtttaggt
     7741 gagaaatatt atcttatgtt tgattttatg attaatcata tttctcgtca atccaagtat
     7801 tataaggact atcaagaaaa acatgaagcc agtgaattta aagatctctt tttaaactgg
     7861 gataagtttt ggccagaaaa ccgtccgaca cagtctgatg tagatttaat ttacaagcgt
     7921 aaggatcgtg caccaaagca agagattgtg tttgaagatg gttcagtgga acatttgtgg
     7981 aatacctttg gtgaggagca gattgatctt gatgtgacca aagaagtaac tatggaattt
     8041 atccgtaaga ccattcagca cttggcaagt aatgggtgtg atttgattcg tctagatgcc
     8101 tttgcttatg cagtgaagaa attggatact aatgatttct ttgtggaacc agatatttgg
     8161 gatttattgg acaaagttcg agatatcgct gctgagtatg ggacagagct tttacctgag
     8221 attcatgaac actattcgat tcagtttaaa atagcagacc atgattacta tgtttatgat
     8281 tttgctcttc caatggtgac actttatact ctttacagtt ccagaacaga gcgtttggct
     8341 aagtggttaa agatgagccc gatgaagcaa tttacgacgc tagataccca tgatgggatt
     8401 ggagtagtag atgtcaagga tatcctgacc gatgaggaga ttgactatgc ttcaaatgaa
     8461 ctctataagg ttggagccaa tgtcaaacgt aagtactcta gtgccgagta taacaactta
     8521 gatatctacc aaatcaattc aacctactat tcagcgcttg gagatgatga tgtcaagtat
     8581 tttctcgctc gtctaattca agcttttgcc ccaggtattc ctcaggttta ctatgtgggt
     8641 ctattagcag gcaagaatga cttgaaatta ttagaagaaa ctaaagaagg tcgaaatatt
     8701 aatcgtcatt actatagcaa cgaggaaata gcaaaagaag tgcaacgacc tgttgtgaag
     8761 gcccttctca atctattttc tttccgtaac cgttcagaag cctttgatct agaagggact
     8821 actgagatag agacaccaac agctcacagc attgtaatca aacgtcaaaa taaagataag
     8881 tccgtaacag cagtagcaga aattgacttg caaaatcaga cttatcgggt aattgagaat
     8941 ggagttgaag taacattttg aagccttgat atggtggata aaatagggtt tttattttgg
     9001 aaaacgtttc ctttgttttc aaattgctaa aaaagtggta caatatagga tagcttacta
     9061 ttatctgaat cagctgattt ggagagaaag gattcatttt gaaatcaata ggctttattg
     9121 aaaagctgaa ggggttgtct agtaaagagc tgattttatt gggaattatc ctgagtatct
     9181 ttttaccctt ttatcttttt gtagttgtat tctgtttata tattatcagt ctgattttta
     9241 caggagacat gaaaagtatt cttcagaaaa tgggggagca ttcgatgctg cttctttttc
     9301 ttggctatag tactgttata tccattcttg cacaaaattg gatgggtctt gtggcttcag
     9361 taggaatgtt tctatttact attttctttt tgcactatca gtcgatttta tcccataaat
     9421 tctttcgatt gattttgcag ttcgtcttgt ttggtagtgt cttgtcagct gcttttgcca
     9481 gtttagaaca tttccaaatt gtgaagaaat ttaactatgc ttttctttcc cccaatatgc
     9541 aggtgtggca tcagaaccgg gcagaagtga ccttctttaa tcctaattat tatggaatta
     9601 tttgttgttt ctgtattatg attgctttct atctgtttac aacgaccaag ttgaattggt
     9661 tgaaagtatt ctgtgtgatt gcaggctttg ttaatctctt tggtttgaac tttactcaaa
     9721 atcgaactgc ctttcctgct attatcgctg gagcaattat ctatctcttt acgactatta
     9781 aaaactggaa ggccttttgg cttagtattg gggtcttcgc gattggtttg agtttcctct
     9841 tttctagtga tttgggagtt cgaatgggta ctttagactc ttctatggaa gaacgcattt
     9901 ctatctggga tgctgggatg gccttgttta agcaaaatcc tttttggggt gaagggccat
     9961 tgacctatat gcactcttat cctcggatac atgctcctta tcatgaacat gcccacagtc
    10021 tttatattga tacgattctg agttacggaa ttgtgggtac cattttatta gttctgtctt
    10081 ctgttgctcc tgttcgcttg atgatggata tgagtcagga gtcggggaaa cgtccgatta
    10141 tcggccttta tctatctttc cttacagtgg ttgctgtgca cggaattttt gacttggctc
    10201 tcttctggat tcagtcaggc tttattttct tgctagttat gtgcagtatt ccattggagc
    10261 atcgaatgtt ggtatcggac atgacggatt aagttttata agtttgaaat cttctacctt
    10321 gggtaggaga ttttttatac gatgggcatg tcgtgcatct gaggtgtaag tcctctgtag
    10381 ggatccacta ccggtgaata caatagcgct ccccaagcct gactatcgtg aggtagcgga
    10441 ttaaaatggt ctggggatag atcgttttaa gtctgacgca ggaaataaga attgtcagag
    10501 aaagcaatag tgaaatcgta ggctatgaat agaaacgtga tagcgaggag catatagtgg
    10561 ataaggtagc gagaaatttt aaagtataaa agatagtctt aatctatata tgtaaatcac
    10621 aaaagtaatt gaattcggaa taaggttggt gtgaaaagac atagtaaact gaatcttgaa
    10681 tactagaatg atacttctac aatattgtta taatttaatt tgaattccaa aatcacattg
    10741 ttccgtccgt atttcatttt actgtatgtc ttcctaaact ccaaagtttc tgcgtcaaat
    10801 ttcctatttt cactgtagtc tttgacactt cgaacgacaa tttgaatcat atattcaaaa
    10861 aaaaatgaaa aatttgtgcc aacaagccta aatattctga aaatttgttt gatttttaat
    10921 ggataatgtg atataatggt tgtcaatcta taattcacat aaacagagga gtagaaaatg
    10981 aaaaaaaatc gtgtatttgc tacagcaggt cttgttttat tagcagcagg tgtacttgca
    11041 gcatgcagtt cttcaaaaac atctgattca tcagccccta aagcttatgg ctatgtttat
    11101 acagcagacc cagaaacctt ggactacctg atttcaagta aaaatagtac aacagtagtg
    11161 acttcaaatg ggattgatgg tttattcact aacgataatt acggtaatct tgctcctgca
    11221 gttgcagagg attgggaagt ctctaaggat ggtttgacct acacttataa gattcgtaaa
    11281 ggggttaaat ggtttacctc tgatggagaa gaatatgcag aggtgacggc taaagatttc
    11341 gtgaacggtt taaaacacgc agcagataaa aaatcagaag ctatgtattt agctgaaaat
    11401 tcggttaaag gcttggcaga ttatctatca ggaacttcaa cagatttttc aacagttggt
    11461 gtcaaggcgg ttgatgatta tacgttacaa tacactttga accagcctga accgttctgg
    11521 aactctaagt tgacctattc tattttctgg cctctgaatg aagaattcga aacatcaaaa
    11581 ggaagcgatt ttgctaaacc aacagatccg acatccttgc tttataatgg tccattcttg
    11641 ttgaaagggt tgactgcaaa atcttctgta gagtttgtaa aaaatgagca atattgggat
    11701 aaagaaaatg tccacctaga tactatcaat ctagcttact atgatggatc agatcaggag
    11761 tcgctagagc gtaacttcac tagtggagct tatagttatg cccgtcttta ccctaccagc
    11821 tccaactatt ctaaggttgc agaagaatac aaggacaata tctattacac acaatcaggc
    11881 tctgggattg ctggtctggg tgtgaatatt gatcgccaaa gttacaacta tacttctaaa
    11941 actacagatt cagagaaagt agctactaag aaggcattgc ttaacaaaga tttccgtcaa
    12001 gccttgaatt ttgctcttga tcgctcagct tactcagctc aaatcaatgg taaagatgga
    12061 gcagctttag cagttcgtaa tttatttgta aaaccagact ttgtttcagc tggtgagaag
    12121 acctttggtg atttagtcgc tgctcaactt cctgcttatg gtgatgagtg gaaaggtgtg
    12181 aatttagctg atgggcagga tggtttattc aatgctgaca aggccaaggc agagtttgcg
    12241 aaagctaaga aagctttaga agcagacggc gttcagtttc ctattcatct ggacgttcca
    12301 gtagaccaag catcaaaaaa ctatatatct cgtattcagt cctttaaaca atctgtagaa
    12361 acagttcttg gtgttgaaaa tgtcgttgtt gatattcaac aaatgacaag tgatgaattc
    12421 cttaatatta cttactatgc tgccaatgct tcatctgagg attgggatgt atcgggagga
    12481 gtttcatggg ggccagacta tcaagaccca tctacttacc tggatatttt aaaaacaact
    12541 agcagtgaaa ctacaaaaac atatttagga tttgataatc caaatagccc ttcagtagtt
    12601 caagttggtt tgaaagaata cgataaatta gttgatgaag ctgccaaaga gacaagcgac
    12661 ttgaatgtcc gttatgaaaa atatgcagcg gctcaagcat ggttgacaga tagttcactc
    12721 tttattcctg ctatggcttc ttctggtgca gcaccagtgc tttcacgaat tgttccattt
    12781 actggagctt ctgcgcaaac aggctctaag gggtcagatg tttacttcaa atatttgaaa
    12841 ttacaagata aagcggtgac taaggaagag tatgaaaaag ctcgtgaaaa atggttgaaa
    12901 gaaaaagctg aatcaaatga gaaagctcaa aaagaattgg caagtcatgt gaagtaaata
    12961 atttctaata gaactttctc tccatgagga gaaggttctt ttgggatttt taaaggaaat
    13021 aatatgaaaa aatatatttt tatgcgtgtt ttgcggtcat tggtttcgat tttcttagta
    13081 acgactttga cctacacgat tatctatacc ttggttcctc gaaaattgat tttcaagcag
    13141 gatcctaact ataataaaat tgcgacaacg gctgataaac gtgataacta tgaaaatact
    13201 gtgtttgagc gtatgggcta cattgagtat tacgatacta aagagttgca agaaaaggca
    13261 agtagcatgg attcttctgt aacagtagaa gcaaatgcga ccaataaagc tatttatgaa
    13321 aagtacatca atcaattagg tcatggttgg actttgggag aatttactga aagtggtcaa
    13381 ttctatgcta ctcgtgaaat tccaattttt gaacgtgttt ttcacttcta tgctaacttg
    13441 attgacattg accatacaaa taaaatccaa gaccctgaaa atccagactt gaaacgctac
    13501 cttcgttttg aaaacgatcc agctatcgga tggtcattgg tcggttcagg aactaaacat
    13561 aaatatctct tgtactttaa cagtcagttc ccatttgttc atcaaaactt tgtgaacttg
    13621 aatttaggtg actcttaccc aacctatgct aatacaccag ttcttcaggt tattactcaa
    13681 ggtcaaggac aaaccaaaac tgcccaagtt cagttcccaa caggtaagaa aacgtcttct
    13741 gtaaatattt actcaagaac ctacaagtca cctagtcagg ctgactctcg tgaagtagct
    13801 agctatggga aagatgatcc ttatacagcg actgaaagta attaccaata tccatctatg
    13861 attgtcagct ctgctattac tggtttgatt ggtttggttc ttgcctatgc tcttgccgtg
    13921 ccacttggtt cagccatggc tcgtttcaag aacacttgga ttgatagcct ctcaacaggg
    13981 gctttgacct tcttgcttgc tcttccaacg attgccttgg tttacatcgt tcgattgatt
    14041 ggatcatcta tttcccttcc agattcattc cctatcttgg gagctggaga ttggcgttct
    14101 tacgttttac cagcagtcat ccttggtttg ttgggtgctc ctggtacagc catttggatt
    14161 cgtcgttaca tgattgactt gcaatctcaa gactttgttc gtttcgctcg tgcaaaaggt
    14221 ttgtctgaaa aagaaatttc aaacaaacac atctttaaaa atgccatggt tccgctggtt
    14281 tcaggaattc ctggtgccat tattggggtt atcggtggtg caacccttac tgaaacagtc
    14341 ttcgccttcc caggtatggg taaaatgttg attgactctg taaaagcatc taataactct
    14401 atggtcgttg gtcttgtctt catctttaca tgtatttcta tcttctcacg tcttttggga
    14461 gatatttgga tgactattat tgacccacgt attaaattga ctgagaaagg aggcaaataa
    14521 tgtctacaat cgataaagaa aaatttcagt ttgtaaaacg tgacgatttt gcctctgaaa
    14581 ctattgatgc gccagcatat tcttactgga aatcagtgtt taaacaattt atgaagaaaa
    14641 aatcaactgt agtcatgttg ggaatcttgg tagccatcat tttgataagt ttcatctacc
    14701 caatgttttc taagtttgat ttcaatgatg tcagcaaggt aaacgacttt agtgttcgtt
    14761 atatcaagcc aaatgcggag cattggttcg gtactgacag taacggtaaa tcgctctttg
    14821 acggtgtctg gttcggagct cgtaactcca tcctcatttc tgtgattgcg acagtgatta
    14881 acttggttat cggtgttttt gtcggtggta tttggggtat ttcaaaatca gttgaccgtg
    14941 tcatgatgga agtttacaac gtcatctcaa acatcccacc tcttttgatt gttattgtct
    15001 tgacttactc aatcggagct ggattctgga atctgatttt tgccatgagc gtaacaacat
    15061 ggattggtat tgccttcatg atccgtgtgc aaatcttgcg ctatcgtgac ttggaataca
    15121 acttggcgtc acgtactttg ggaacaccaa ccttgaagat tgttgccaaa aatatcatgc
    15181 ctcaattggt atctgttatt gtgacaacca tgactcaaat gcttccaagc tttatctcat
    15241 acgaagcctt cttgtctttc ttcggtcttg gattaccgat tacagtgcca agtttgggtc
    15301 gtttgatttc ggattattca caaaacgtaa caaccaatgc ttacttgttc tggattccat
    15361 tgacaaccct tgtcttggta tccttgtccc ttttcgtagt tggtcaaaac ttagcggatg
    15421 ctagtgatcc acgtacacat agataggagt agaaatgaca aaagaaaaaa atgtaatttt
    15481 gactgctcgc gatattgtcg tggaatttga cgttcgtgac aaagtattga cagccattcg
    15541 cggcgtttcc cttgaactag tcgaaggaga agtattagcc ttggtaggtg agtcaggatc
    15601 aggtaaatct gttttgacaa agaccttcac aggtatgctc gaagaaaatg gtcgcattgc
    15661 ccaaggtagt attgactacc gtggtcagga cttgacagct ttatcttctc acaaggattg
    15721 ggaacaaatt cgtggtgcta agattgcgac tatcttccag gacccaatga ctagtttgga
    15781 ccccattaaa acaattggta gtcagattac agaagttatt gtaaaacacc aaggaaaaac
    15841 agctaaagaa gcgaaagaat tggccattga ctacatgaat aaggttggca ttccagacgc
    15901 agatagacgt tttaatgaat acccattcca atattctgga ggaatgcgtc aacgtatcgt
    15961 tattgcgatt gcccttgcct gccgacctga tgtcttgatc tgtgatgagc caacaactgc
    16021 cttggatgta actattcaag ctcagattat tgatttgcta aaatctttac aaaacgagta
    16081 tcatttcaca acaatcttta ttacccacga ccttggtgtg gtggcaagta ttgcggataa
    16141 ggtagcggtt atgtatgcag gagaaatcgt tgagtatgga acggttgagg aagtcttcta
    16201 tgaccctcgc catccatata catggagtct cttgtctagc ttgcctcagc ttgctgatga
    16261 taaaggggat ctttactcaa tcccaggaac acctccgtca ctttatactg acctgaaagg
    16321 ggatgctttt gctttgcgtt ctgactacgc aatgcagatt gacttcgaac aaaaagctcc
    16381 tcaattctca gtatcaaaga cacattgggc taaaacttgg cttcttcatg aggatgctcc
    16441 aaaagtagaa aaaccagctg tgattgcaaa tctccatgat aagatccgtg aaaaaatggg
    16501 atttgcccat ctggctgact aggaggaagg aaatgtctga aaaattagta gaaatcaaag
    16561 atttagaaat ttccttcggt gaaggaagta agaagtttgt cgcggttaaa aatgctaact
    16621 tctttatcaa caagggagaa actttctcgc ttgtaggtga gtccggtagt gggaaaacaa
    16681 ctattggtcg tgctatcatc ggtctaaatg atacaagtaa tggagatatc atttttgatg
    16741 gtcaaaagat taatggtaag aaatcgcgtg aacaagctgc ggaattgatt cgtcgaatcc
    16801 agatgatttt ccaagaccct gccgcaagtt tgaatgaacg tgcgactgtt gattatatta
    16861 tttctgaagg tctttacaat caccgtttat ttaaggatga agaagaacgt aaagagaaag
    16921 ttcaaaatat tatccgtgaa gtaggtcttc ttgctgagca cttgactcgt taccctcatg
    16981 aattctcagg cggtcaacgt caacgtatcg gtattgcccg tgccttggtc atgcaaccag
    17041 actttgttat tgcagatgag ccaatttcag ccttggacgt ttctgtacgt gcccaagtct
    17101 tgaacttgct caaaaaattc caaaaagagc tcggcctgac ctatctcttc atcgcccatg
    17161 acttgtcggt tgttcgcttt atttcagatc gtatcgcagt tatttacaag ggtgttattg
    17221 tagaggttgc agaaacagaa gaattgttta acaatccaat tcacccatat actcaagcct
    17281 tgctttcagc ggtaccaatc ccagatccaa tcttggaacg taagaaggtc ttgaaggttt
    17341 acgacccaag tcaacacgac tatgagactg ataagccatc tatggtagaa atccgtccag
    17401 gtcactatgt ttgggcgaac caagccgaat tggcacgtta tcaaaaagga ctaaactagt
    17461 aatggtttta taatttccat gtcaattttt atggaaatta taaaactttt tttgttggac
    17521 tgatttgaaa aactttgaaa gcttcctgaa agaatttttg aaaaatttta aaaattatga
    17581 aatgttattg acaggtgatg aaaaaggtgg taggacagga agcatcaaaa aagaaagcag
    17641 aaaaagaaat gaataagaga caagccgtaa ctatgaatca aaacttttac tttagctact
    17701 ttagatagtg tttgtagaca tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta
    17761 tctatgtggc taagattttt gattgtggtc catatagatg aatatctaaa tggactagct
    17821 aagttgtaac ttgttaggtt atttcaagta tccgtttaga tagtatctag gcggtttttt
    17881 gttttatctt ttctgagaag gagtttcatt atgaaagttg ttcgaaaatc actagccccc
    17941 tcttggtagt ggggctcctc ttgacttctc tgatcagttt gcatcagttg aaggcagata
    18001 agaaaaagat gtctttcgta tcggtatttc gcaatttatt acccaccagt ccttatacgc
    18061 tactagagaa ggatttgtgg atgagctggc caaacaaggc tatgttgagg gggaaaatat
    18121 tgagattgat ttgcaaaatg cacagggaga acaaagaaat ctaaaaacga tttcccagca
    18181 actagcagaa tccagcgatg tcgttctagc catcgcaagg ccttctgctc agagcttggc
    18241 caatacgacg caaacgacac cagttatctt ttcagctgta acagacccag tcagtgccaa
    18301 gttggttgag tcaagagaac atcctggggg caatgtaact gggacaagcg atcagtcatc
    18361 agatgccatt tcaacccaaa tcaatttgat aaagaaagtg ttgccaaagg ctaaaacgat
    18421 tggaatcctc tatactcaga gcgagcccaa ttcggttgtt caaaaggatg aagctaagcg
    18481 acttctgaaa gaaaaaggct ttaccgttgt tgaaaaaaca atcttggaca gtaataacgt
    18541 caaggcggca gcagagagtt tgatggcaga ggtggatatg gtttttgtcc caactgataa
    18601 tatcatttcg ttaaccatgg aaacagttaa gcaggtttct attaaacaca aggttccagt
    18661 attcggtggt tcaacagaaa tgattgctgt tggtggcttg tataactacg gaaccaatta
    18721 tgaagaattg gtacgtcaga cagctcgcat gctgattcgt gttttaaaag gtgagaaacc
    18781 agaaaatata gcagttgagt tgcctgaaaa actggaattg cataccaatc aagaaatggc
    18841 agatgcattg ggaattgata ttagtaagtt agaaggcaag gaataaggag gattaagatg
    18901 aattttgtgt tatctagttt atcagaaggt ttgttgtggt cgattgtggc gattggggtc
    18961 tacttgactt tccgtatttt ggatattgcg gatatgactg ctgagggagc ctttcctctg
    19021 ggggcagcag tcgttgtatc acagatacag gcaggggcaa atccttggct tgcgacttta
    19081 cttgctttgc tgacaggtat ggtagcaggt cttgtatcag gaatgctcca caccaagatg
    19141 aaaatcccag ctctcttgac agggattgtg accttgacag ggctctattc aatcaatatt
    19201 aaaatcatgg gcagtgtacc caatctttcc ttgggagatt ctgcaaccgt ctttaaacag
    19261 ttggcgagct tgggtctgac aaatgaagga actgttttct cacttagttt ggcctgtttt
    19321 ttacttgttt gtttggtctt gacccttttg atgaaaacag agattggcct ggtcttgcgt
    19381 tcgactgggg ataatatccc gatgagtgag gccaatggag tcaatgtaga caccatgaag
    19441 attgttggtt acatgatttc aaacggtttg attgctctat gtggttcctt gtttgcccaa
    19501 aatgatggat tttcagatgt gacttctggg acaggaacca ttgttgttgg tttgagctcg
    19561 gtgattattg cggaagtctt gatacacgac ttgaccattg gaggccgctt attatccatc
    19621 ggaatcggtg ctattgttta ccgtttgatt attttaaata tctatgaaat tccaaatcta
    19681 gatcaaaact tggtacgtct ctttaatgca atcttgctcg ctttggtttt atttgcacca
    19741 gaattgcaaa agagattaaa gattcgtggt ctgaaattga gaaatgaata ggaggagaaa
    19801 gttatgacaa gtttgttaac acttgaaaat attcacaaga catttgaagc agggacggtc
    19861 aatgagaacc atgtcctcaa aggattagat ttagaggttg aagagggaga ttttatctct
    19921 gtgattggtg gaaatggagc aggaaaatcc actttgatga atatcttggc tggcaatcta
    19981 tcggtggacg aaggggacct tctactggca gggaaatcca ttaaaaatct gagtgtcaga
    20041 aagagagcca aggatattgc ccgtgttttt caagatccta agatgggaac agcttctcgt
    20101 ttgacgattg aggagaatat ggctattgcc ttgagacgcg ggcagaagag agggcttggt
    20161 tggggcgtga aggagaagga tagaatccag ttccaagagg ccttgaagga gttgaatatt
    20221 ggtcttgaaa accgcttaaa agtagatact caatatctct caggaggaca aagacaggct
    20281 ttgactctag tcatgacaga tctgatgaaa ccaaaacttt tacttttgga tgaacatact
    20341 gcggcacttg acccgaaaac cagtcaaatg gtgatggact tgacgcaaaa gattgtggag
    20401 caccatcagt ggacgacttt gatgattacc catgatatga atcatgcgat tgagtacggc
    20461 aatcgtctca ttatgctcta tcaaggcaag atagtggtgg atgtcaaggg agaagagaaa
    20521 aagcatctga cagttgaaga ccttatgcat ctcttccaga aaaatagtgg ccaaagtctg
    20581 gtcagtgatg aattagtttt gggataaaga aaaaggctga gatctggtgt ctcagtcttt
    20641 tatttcttgc gttttgcaaa atctacaaat ctaaatttct ctaacttatg gcgactttcg
    20701 gtaaactgaa attggcgtcc gtcttggaga tagacttttg atttaatcga aacgacataa
    20761 gggtctttgc caatgtccat gagaatcttg tctcggtcgc ttgagtggtc aatggtgatt
    20821 tccttctgag cataatcaat aaggagtttg aggccatttt ctatataaga atagatagac
    20881 tgctcagcaa tttggcgagt gagatttgga attagttcca tatccagata gtccgtatcc
    20941 agaacggata ccagatcatc caccacacgc tggcggacca ccttccaaac catccgaaac
    21001 tctgggaaac cggttatcag tgaggatttt ttatcaataa taatcttgtc cagactgacc
    21061 acgttggttt tagagcgcag tccaagttct ttaactagtt cttggtagct ggttaggttg
    21121 gatacaggga aattgacggt ttcttctttg acgacttgag aaccttgctc tcttatcttt
    21181 ttgatcaatc cttcctcttg gaggagagac agggcctttc ggacggtatc acgactcact
    21241 tgatattgct ccataaggtc gtgctcgcta ggaaggaaat ctccgacagc gtaagtctcg
    21301 ttttgaatgg tttcttggat ttgcttaaat aattgttggt atttcttcat tttgcctgct
    21361 ttaataggtt tttagtctag tttaatgaac acctgtatct attttaccat acaagtgcta
    21421 gaaaatttac aaaaaaacac cctttttata ccaaacaagt tgcagacaag tttggtatcg
    21481 tttacaatat acttatcaaa tcaaacttgc tttgacaagt ataaggagaa tcaaatggga
    21541 aaatttgaac aagaagccaa agatctgctt caggcaattg gaggcaaaga aaatgtgact
    21601 gccgtaactc actgtgcgac acggatgcgc tttgttttag gagatgataa gaaggctaat
    21661 gttaaagcta tcgagtcaat tccagctgtt aaaggaactt ttacaaatgc aggtcaattt
    21721 caggtaatca ttggaaatga cgtgcccatc ttttataatg attttacagc cgtttcaggt
    21781 attgagggtg tttccaaaga agcagccaag tctgcagcta agagtaatca aaacgtggtc
    21841 caacgtgtta tgaccactct ggcggagatt tttactccga ttattccagc cttgatagtc
    21901 ggaggattga tcctcggttt ccgtaatgtc ttggaaggtg tccattggtc gatgttggat
    21961 ggcaagacca tcacagaatc ctctcagttt tgggcaggtg tcaatcactt cctctggttg
    22021 cctggtgaag ctatcttcca gttcttacca gtagggatta cttggtctgt ttctcgtaag
    22081 atgggaacca gccaaatttt gggaattgtt ctcggaatct gtttggtatc gcctcagttg
    22141 ctcaatgcct atgcggttgc ttcaacgcca gcagctgata tcgcggcaaa ctgggtttgg
    22201 aattttggct attttactgt taatcgtatc ggttaccaag cccaagttat cccagccttg
    22261 cttgcaggtt tgagtctgtc ttatcttgaa atcttctggc gcaagcatat cccagaagtc
    22321 atttctatga tttttgtacc tttcttgtca ttgattccag ccttgatttt ggctcatact
    22381 gttttgggac caatcggttg gacaattgga caaggacttt catcagttgt cttggcaggt
    22441 ttaactggtc cagttaaagg gctcttcggt gcaatttttg gtgccctcta cgctccattt
    22501 gtcatcacag gtctgcacca tatgaccaat gccattgata cacaattgat tgcggatgct
    22561 ggtggcactg ccctatggcc aatgattgct ctttctaata ttgctcaagg ctcagccgtg
    22621 tttgcctatt atttcatgca tcgccatgat gagcgtgagg ctcaggtttc acttcctgca
    22681 accatttcag cctatctcgg tgttacagaa ccagctcttt ttggggttaa cgtaaaatat
    22741 atttatccat ttgttgctgg gatgactggt tcagcccttg caggcatgtt atccgttact
    22801 tttaatgtaa ctgcggcttc tattggtatc ggtggtttgc caggtattct ctctattcaa
    22861 cctcaataca tgctgccatt tgcaggaact atgctagttg cgattgttgt tccaatgctc
    22921 ttgactttct tcttccgcaa ggctggtctc tttacaaaaa cagagggcga tacgaacttg
    22981 caggcagaat tcgttgctca agaagaagca gaatttgtga accatgaacc agtagaactt
    23041 acttcggtag aaattatcag cccactaact ggccaagtga aagaattgag tcaagcgacg
    23101 gatcctattt ttgcatcagg tgtcatgggg caaggtctgg tcattgaacc aagccaaggt
    23161 gagttgacct ctccagttaa tgggacagtg acggttcttt tccctaccaa gcatgccatc
    23221 ggcattgtct ctgacgaggg agttgaattg ctcatccaca tcggtatgga tacagtaggt
    23281 cttgatggca aaggttttga aagtcttgta gtccaaggag atcacgttac agttggtcag
    23341 caactgattc gttttgatat ggatgtcatt aaggctgcag gtctggtgac agaaactcct
    23401 gttatcatca ccaaccaaga tgcttataca gcgactattc ccggaactta tccgacaacg
    23461 attcaagctg gagcatctct catggtcgct acacgaatct aatactcttc gaaaatctct
    23521 tcaaaccacg tcagctctat ctgcaacctc aaaacagtgt tttgagcaac ctgtggctag
    23581 cttcctagtt tgctctttga ttttcattga gtataattga aatagcacaa atagggacgg
    23641 aagactgctt cctccctttt atcagaaaag gagaaacaga tgacacttga taaaggaaaa
    23701 gtagtctatc aaatctatcc aaaatcttac aaagacacca ctgaaaacgg tattggggat
    23761 ttccgtggga ttatcgaaaa aattccctat ttagccaaac taggcgtgga tatggtctgg
    23821 ctcaatccat tctatccaag ccctcaacgg gataatggtt acgatatttc agattatatg
    23881 gcagtggatc ctctttttgg tgatatggct gattttgagg aaatggtgtg tgtcggtaaa
    23941 gagcacaaga ttgactttat gctggacatg gtacttaatc attgttcgac agagcatgaa
    24001 tggtttcaga aagccctagc tggtgataag tattatcaag actttttctt catccaagac
    24061 caaccaacag attggcagtc taagtttggt ggttctgcat gggcgccttt cggggatact
    24121 gggaaatact atcttcacct atttgatgag acccaggctg accttaactg gcgcaattcc
    24181 aatgtccgta aggagctttt caaggttgtt aatttctggc gcgacaaggg tgtcaaaggt
    24241 ttccgatttg atgtgatcaa tttgatcggt aaggacgagg tttcagtgga ctgtcctgaa
    24301 aatgaaggga agccagctta tacagacaaa cccatcgttc ataactattt gcgtatgatg
    24361 aaccaagcca cttttggatc tgacgatagc tttatgacag ttggggaaat gtcttctacc
    24421 accatggaaa actgtgtcct ctattcgtcg cctgatcgtc aggaattatc catgaccttt
    24481 aattttcatc acctcaaggt ggactataag gatggacaaa agtggacctt ggctcccttt
    24541 gattttgaag agttgaagag tctttaccat agttggggta aggaaatgag tgataaagac
    24601 ggttggagtg ccctcttttg gaacaatcac gatcaaccac gtgccttgaa ccgttttgtc
    24661 gatattcaaa acttccgcaa ggaaggagcc accatgctag cagccagcat tcacctgtca
    24721 cgtgggacac cttatatcta catgggtgag gaaatcggga tgattgaccc agactatgat
    24781 tctatggctg attatgtgga tgtcgaatcg cttaatgcct atcagatgct cttagaagaa
    24841 ggaaagagtc agcaagaagc cttccagatt attcaagcta agtcgcgtga taattcacgt
    24901 attcccatgc agtgggatac ttctgaaaat gcaggatttt caacaggcac tccatggttg
    24961 aaagtcggta aatcctataa agatatcaat gtagaaaatg aaatcaaagg tctgattttc
    25021 accttctatc aagacttgat tcgactgcgt aaggaaatgc caatcatttc agaaggaaat
    25081 tacaaaccag cctttgaaga tagcaaacaa gtctacgctt ttgaacgcca gtttgaggat
    25141 caaaagttac tagtgctcaa taacttttat gccaaagaag tggaaatcga cttgccagca
    25201 gtctaccaaa atggacagat tttgatttca aactatgaag atgcagaagt gtctgagaaa
    25261 attctactca aaccctatca aacactggct atttatgtaa attaatactc ttcgaaaatc
    25321 tcttcaaacc gtgtcagttt tatctgtaac ctcaaagcgg tgctttgagc aacctgtggc
    25381 tagcttccta gtttgctctt tgattttcat tgagtataaa cttagcaagg agacctcttt
    25441 ttcagaaaag cagggttctt tttgctgtct attccatcct tgaaagtgta gaacaaactg
    25501 gtcagggtgg ctagtttgtg gtataatgaa agggattcaa aaagaaacag gagaaaaatg
    25561 atggatttac ttttagcaat tgtattgatt gtgctagctt ttctaggagg agctcttgga
    25621 ggaatgtact tggttcgtaa gcaaatcgaa aaagaatttg ctgacaaccc acgtttgaat
    25681 gctgaagcag ttcgtactct tttgagtgca aatggtcaaa aaccaagcga agctaaggta
    25741 caacaagttt accaccaaat catccgccaa caaaaggcag cccttgctaa caataaaaag
    25801 aaaaaataaa taaggaaaag tctgggatga aagttccaga cttctcacta tgttggttat
    25861 ggtttaggga tgagactttt tccttgcatt ctattgatat ttgattatga ttaagagaga
    25921 ggtagttgac attctatcaa gctgtcggtc agttcgttca gtacaaggaa tcataatgaa
    25981 cgatcaatca gaaaaaagac tagaaagaag actgtatgga taatcgacca attggttttt
    26041 tggattcggg tgtcgggggc ttgaccgttg tgcgcgagct catgcgccag cttccccatg
    26101 aagaaatcgt ctatattgga gattcggcgc gggcgcccta tggcccccgt cctgctgagc
    26161 aaattcgtga atatacttgg cagctggtca actttctctt gaccaaggat gtcaaaatga
    26221 ttgtcattgc ttgtaacact gcgactgcgg tcgtctggga agaaatcaag gctcaactag
    26281 atattcctgt cttgggtgta attttgccag gagcttcggc agccatcaag tccagtcaag
    26341 gtgggaaaat cggagtgatt ggaacgccca tgacggtaca atcagacata taccgtcaga
    26401 aaatccatga tctggatccc gacttacagg tggagagctt ggcctgtccc aagtttgctc
    26461 ccttggttga gtcaggtgcc ctgtcaacca gtgttaccaa gaaggtggtc tatgaaaccc
    26521 tgcgtccctt ggttggaaag gtggatagcc tgattttggg ctgtactcat tatccactcc
    26581 ttcgccctat tatccaaaat gtgatggggc caaaggttca gctcatcgat agtggggcag
    26641 agtgcgtacg ggatatctca gtcttactca attattttga aatcaatcgt ggtcgcgatg
    26701 ctggaccact ccatcaccgt ttttacacaa cagccagtag ccaaagtttt gcacaaattg
    26761 gtgaagaatg gctggaaaaa gagattcatg tggagcatgt agaattatga caaataaaat
    26821 ttatgaatat aaggatgacc aggactggta tgttgggtct tatagtattt ttggtggcgt
    26881 taacagtttg agcgactata agacagattt tcctctgttt gaattctcca aaatatttgg
    26941 agatgaagag tatggtttcc cgctttcagt tactgtttta cgctatggtt ctacctaccg
    27001 tttgttctcc tttgtggtag acatgcttaa tcaagaaatg ggacgaaact tggaagttat
    27061 tcaacgtcat ggggccctgc tcttggttga aaatgggcaa ctcttgtatg tagaattgcc
    27121 taaagaaggg gtcaatgttc atgatttctt tgagacaagc aaggtcagag aaaccttgtt
    27181 gattgcgact cgtaacgaag gtaaaaccaa ggaattccga gctatctttg ataagttagg
    27241 ctacgatgtg gaaaatctta atgactaccc tgacctgcct gaagtagcag aaacaggtat
    27301 gacctttgaa gaaaatgccc gccttaaggc agaaaccatt tctcaattaa cgggcaagat
    27361 ggttttggca gatgattctg gtctcaaagt cgatgtcctt ggtggcttac caggcgtctg
    27421 gtcagctcgt ttcgcaggtg tgggagcaac tgaccgtgaa aataatgcca aactcttgca
    27481 cgaattggcc atggtctttg aactcaagga ccgctcggct cagttccaca caaccctagt
    27541 cgtagccagc ccaaataagg aaagtttagt tgttgaagca gactggtcag gttatattaa
    27601 ctttgaacct aagggtgaaa atggctttgg ctatgatccc ctcttccttg taggagagac
    27661 aggtgagtca tcagctgaat taaccctaga agaaaaaaat agtcaatctc accgtgcctt
    27721 agccgttaag aaacttttgg aggtatttcc atcatggcaa agcaaaccat cattgtaatg
    27781 agcgattccc atggcgatag cttgattgtg gaagaagtcc gtgatcgcta tgtgggcaaa
    27841 gtcgatgccg tttttcataa cggcgattct gaactacgtc cggattctcc actttgggag
    27901 ggcatccgcg ttgttaaagg gaacatggac ttctacgccg gctacccaga acgtctggtg
    27961 actgagcttg gttcgaccaa gattatccaa actcatggtc acttgtttga catcaatttc
    28021 aactttcaaa agttggacta ctgggctcag gaggaagagg ccgctatctg cctctatggt
    28081 cacttgcatg tgccaagtgc ttggttggaa ggcaagatcc tctttctaaa tccaggttct
    28141 atcagtcaac cacgaggtac catcagagaa tgtctctatg ctcgtgtgga gattgatgat
    28201 agttacttca aagtggactt tttgacacga gatcacgagg tgtatccagg tttgtccaag
    28261 gagtttagcc gatgattgcc aaggagtttg agactttctt gttggggcag gaggaaactt
    28321 ttttgacccc tgctaaaaat ctagctgtgt tgattgatac ccacaatgcg gatcatgcga
    28381 ccctcttgct cagtcagatg acctataccc gtgttcccgt tgtgacagat gaaaaacagt
    28441 ttgttgggac gattggactc agagatatta tggcttatca gatggagcat gacttgagcc
    28501 aagaaatcat ggcggatacg gatatcgttc atatgacaaa aacggacgta gcggttgttt
    28561 cgcctgattt caccattacg gaggtcttgc acaagctagt agatgagtcc ttcttaccgg
    28621 tcgtggatgc agagggtatt ttccaaggga ttattacgcg caagtccatc ctcaaggccg
    28681 ttaatgccct cttgcatgac tttagtaagg aatatgagat tcgatgccaa tgagagacag
    28741 gatttcagcc tttttagagg aaaagcaggg cttgtctgtc aattccaagc agtcctataa
    28801 gtatgatttg gagcaatttt tagacatggt aggtgagcgg atttctgaga ccagtctcaa
    28861 gatttaccaa gcccagctag ccaatctaaa aatcagcgcc cagaagcgaa agatttcggc
    28921 ctgtaaccaa tttctatact ttctctatca aaaaggagag gtggacagct tttaccgctt
    28981 ggaattagcc aaacaagctg aaaagaagac ggaaaagcca gagattctat acctagactc
    29041 tttttggcag gaaagcgacc atccagaggg ccgcttgcta gcgctcttaa tcctagaaat
    29101 ggggctcttg cccagtgaga ttttagccat caaggttgcg gacatcaatc tggattttca
    29161 ggtgctgcga atcagcaagg cttcccaaca gaggattgtc accattccca cggccttgct
    29221 ttcagaattg gaacccttga tggggcagac ctatcttttt gaaagaggag agaaacccta
    29281 ttctcgtcag tgggcctttc gtcagttaga atcttttgtc aaggagaaag gttttccatc
    29341 cttatcagct caagtcttac gtgaacagtt tattctaaga caaatagaaa acaaggtcga
    29401 tttgtacgaa attgcaaaaa aattaggatt aaaaacagtc ctgaccttag aaaaatatag
    29461 ataatggata ttaaattaaa agattttgaa ggacccctgg acttgctctt gcatctggtt
    29521 tctaagtacc agatggatat ctacgatgtg cccattacgg aagtcatcga acagtatcta
    29581 gcctatgtct caaccctgca ggccatgcgt ctggaagtga cgggtgagta catggtcatg
    29641 gctagtcagc tcatgctgat taagagtcgt aaactccttc cgaaggtagc agaagtgaca
    29701 gacttggggg atgacctgga gcaggacctc ctctctcaaa tcgaagaata tcgcaagttc
    29761 aagctcttgg gtgagcactt ggaagccaag caccaagaac gggcccagta ttattccaaa
    29821 gcgccgacag agttgattta cgaagatgcg gagcttgtgc atgacaagac gaccattgac
    29881 ctctttttgg ctttttcaaa tatcctagcc aagaaaaaag aggagtttgc acaaaatcac
    29941 acgacgatct tgcgggatga gtataagatt gaggacatga tgattatcgt gaaagagtcc
    30001 ttgattggac gagatcaatt gcgcttgcag gatttgttca aggaagccca gaatgtccaa
    30061 gaggtcatca ccctcttttt ggcaacccta gagttaatca aaacccagga gctgatcctc
    30121 gtgcaagagg agagttttgg agatatctat ctcatggaaa agaaggaaga aagtcaagtg
    30181 cctcaaagct agacttgata gagaggaaag atgagtactt tagcaaaaat agaagcgctc
    30241 ttgtttgtag cgggtgaaga tgggattcgg gtccgccagt tagctgaact cctctctctg
    30301 ccaccgacag gcatccagca aagtttagga aaattagccc agaagtatga aaaggaccca
    30361 gattccagtt tggctttgat tgagacaagt ggtgcttata gattggtgac caagcctcaa
    30421 tttgcagaga ttttgaagga atactctaag gcgcctatca accagagctt gtctcgggct
    30481 gcccttgaga ccttgtccat tattgcctac aaacagccga ttacgcggat agaaattgat
    30541 gccatccgtg gagttaactc gagtggagcc ttggcaaagt tgcaggcttt tgacctgata
    30601 aaggaagacg ggaaaaagga agtattgggg cgccccaacc tctatgtgac tacggattat
    30661 ttcctagatt acatggggat aaaccattta gaagaattac cagtgattga tgagcttgag
    30721 attcaagccc aagaaagcca attatttggt gaaaggatag aagaagatga gaatcaataa
    30781 gtatattgcc cacgcaggtg tggccagtag gagaaaagca gaagagctga ttaagcaagg
    30841 cttggtgacg gttaacggcc aagtggtgcg tgaactagca accactatca agtcaggcga
    30901 caaggtcgaa gttgaaggtc aacctatcta caacgaagaa aaggtctact atctgcttaa
    30961 caaaccacgc ggtgtgattt ccagtgtgac agatgataag ggtcgcaaga cggttgtcga
    31021 cctcttgccc aatgtcaaag agcgtattta ccctgtgggt cgtttggact gggatacatc
    31081 aggtgtcttg attttgacca atgatgggga ctttacagac gagatgattc accctcgtaa
    31141 tgagattgac aaggtttatg tcgcgcgtgt taaaggtgtg gccaataagg acaatctccg
    31201 ccccttgacc cgtggtcttg agattgatgg taagaaaacc aagccagctg tttatgaaat
    31261 tctcaaagtg gacccagtca aaaatcgctc tgtggtgcag ttgaccatcc atgaagggcg
    31321 taaccatcag gttaaaaaga tgtttgaagc tgttggtctc caagtagata agttgtctcg
    31381 gactcgtttc ggacacctag acttgacagg actccgtcca ggagaatccc gtcgtcttaa
    31441 taaaaaagaa atcagccaac tacacaccat ggctgtaact aagaaataat gaaacgaatt
    31501 ttaatagcgc ctgtgcgctt ttaccaacgt tttatctcac cagtctttcc accctcttgt
    31561 cgctttgagc tgacttgttc caactacatg attcaggcta ttgaaaaaca tggttttaag
    31621 ggggtattga tgggcttggc tcggatttta cgttgtcatc cctggtcgaa aacaggtaag
    31681 gaccccgttc cagaccactt ttcccttaaa cgaaatcaag aaggggaatg aggtggggta
    31741 aatagatttc aaaatgataa aaacgcatcc tatcaggttt gagtaaactt gataggatgc
    31801 gttttagaat gtcaaaattt tatactcttc gaaaatctct tcaaaccgcg tcagctttca
    31861 tctgcaacct caaaacagtg ttttgagcaa cctgcggcta gtttcctagt ttgctctttg
    31921 attttcattg agtattaaat tgagtttgaa gtggcttatt tcaaagcttt ttgtatgtct
    31981 tcaatcatga gttttgttga ttcaagtccg cctccgctta gataccagag gtctggtgtt
    32041 agttggataa tcttaccatt tttagcagca ggtgtttcag cgataagggc attttctagg
    32101 acaccgtcgt tgctagagtt gtccccaccg atggcaaggg tacggttgat gacaaagagg
    32161 atgtcagggt tgatttcttt gacactttca aagctgactt cttgtccgtg gcgtgagtct
    32221 tcaaattttg tatcagttgg tttgaatttc aaggtttggt acaagaaaga gaaacgagat
    32281 ttggcaccaa aggctgccat ttttccttca ttaaggagga tcgcaagggc ttttttgtca
    32341 gagctttcat ttttagtagc gacttcttgg atgctcttgt ctagcttggc caattcttcc
    32401 ttggctttct gtgtaccagt ttcgccgaag gcacttgcta aggattcgat attagccttg
    32461 gtagaagtcc agtagtcgtc cttgcttgct tggaagagaa cggttggggc gatttctttg
    32521 aatttgtcta cgaatttttg tgtacgtggt gaagcgataa tcaaatcagg ctcaagggcg
    32581 gcgatagctt ctaaatcagg ttctttcata gaaccaacat ttttgacagt tcccactagg
    32641 tcttttagat aagtcggaac agtttttgta ggcattccga cgatattttt ttcaaatcct
    32701 aaagcgcgaa tagtatccgc agcgccgagg tcaaaggtca caatcttttc aggaactttg
    32761 gaaagtttga cctcggccag tgaactttta atggttacct ctgttggagc agagctactg
    32821 gtctctgtct gactagtgct tgagtttgta ctacatgcac caagtaggag caagaagctg
    32881 gccactaggg cagtgaaata aagtttaagg gatgttttca taatttctcc tctttaaaat
    32941 gtgataacga tttagggagt ctcttgatct tattgactaa gagactgaag gttctctaac
    33001 ttgagctttt atgttactag ctatagatac agatcttttt gtcattgata tcagctagcg
    33061 tgatgggaat ctcataaagt tgactgagca ggtcagcctg catgatttga tcggttcttc
    33121 ccttgctaaa gacctggccg tccttgaagg cgacaatttc atctgcatac tgactggcta
    33181 tgttgatatc gtggaggacg atgataatgg tcttgccgag ttcctccacc agtcgtcgaa
    33241 gaatctgcat catgctgacg ctttgcttga tatcgagatt gttgagtggt tcgtccagca
    33301 agataaagtc cgtatcctgg gccagtacca tagcgataaa gacgcgctgg agttgccccc
    33361 ctgacaggct attgatgtag cggtctttta agttggtcag ttccaaatag ttcagagttt
    33421 ctcggatttt ttcccagtct tctgatctaa gtcgacctcg gctgtaggga aaacgtccaa
    33481 aactgaccag ttcttcaaca gtcaatttgg cttggtaatt gattttctgt tttaggatgg
    33541 ttagttcttg ggccagttct tgcgaattcc agctctcgat ttcacgtcct ttgatactga
    33601 gaactccctg atctttcttg gttagtctgc tcatgatgga gaggagagtc gattttccag
    33661 caccatttgg accaataaag gctgtcagtt tttgaggact gacttcaagc gaaatgcctt
    33721 gcaaaatatc ctgtttttga atggatttgt caatgttttc cagtttcact gacgagccct
    33781 cctatatagt aagataaaga ataagaagcc acccacactc tcaatgatca tactgatacg
    33841 aatttccagt gcaaagactc gttcaatcaa ggcttgcccc aaggttaagc taataaatcc
    33901 aaccagaatg gccactataa agagtaactt gtgctgatag tctttgacaa tcaggtaggt
    33961 gaggttggcc agcataaagc cgaagaaggc cataggtcct accaaggcag tggccgttga
    34021 ggtcaaaagc acgattcccc agaggagctc tttctgttct ttttcaacat cgagtcccaa
    34081 tatctgagcc gtttctcttt gcaggtgcaa gacatctaga acgactgctt ttcgaaagaa
    34141 aaagattgtc aaagcgagga tgatcagaga accgatggct aggatggaag tgttgagatg
    34201 ttgaaaggag gcaaaaagac tattttgcag tttatcgtat tcgtttggat ccattaggac
    34261 ttgaaggaag gtgctgatat ttcgaaagag acttctgagc gctagacaga tcagcaggat
    34321 gaagaccagg tcttgcttca tcagtgtctt caagtaacct tgtaaggcga gaaagaagag
    34381 ggactggaca agaagtaaga ctaggaattc taagataggg gatttgccaa gttgaagaaa
    34441 cttgctttca aaaaccagta gtagggtttg tagtaggacg tagaaggatt caattcccaa
    34501 aatactaggc gtcaggaagc gattttccgt cagggtttga aaactaatgg tcgaaatccc
    34561 agtcgcgatg gctaccaaga gataaacgat gatcttttgg gaacgcaact tccaagcaaa
    34621 ggctgacaag tgagtgatgg gccaaaagta gagaagacaa gctccgatgg caagaataat
    34681 gagaatccag aagagcttgg tatgtttgct tttagtctgc atcttttcgt ccccctctcc
    34741 agagaagtag gataaagacg agactaccga tgattcctag caagagactg acagacaact
    34801 catagggcct aatcagaact cgggatagga tatcgcaagc cagaactaga ttggcaccaa
    34861 ccagtgcgac catgagtttg gtttgactta gattatctcc atagcgcttg cgaacaagat
    34921 tgggaacgat aactccgaga aatggtaggc cacccacggt aatcatggtg acgcttgtcg
    34981 ttagcgccac cagaaagagg gccagttttt caagtaggga gtaggaaatc cccaaactct
    35041 cgctggtttc tttccctaga ttcatgatgg tgaaggtttg ggataatttc caaacggtta
    35101 tcaggatgat gaggcctaag aagagccact catactgatg ggtctgaatc atggagaagg
    35161 agccctgggt ccaggcagtc atactctgaa ccagattgaa acgataggcg ataacttctg
    35221 tgactgagcc gataatcccg ctatagatga tcccaatcag aggcaacatc cacctttcct
    35281 ttacagtaaa aatggtcata aaggctagga agaagagggt gaatacgatg gatgaaacaa
    35341 aagcgaagag catcttttgg gtcagactag ccgatggaaa gacaaaaagg ctcagcacca
    35401 ttcccagttt ggcggcttca gtcgttccaa ctgtactcgg tgcagcaaac tgattttggg
    35461 taatagtctg catgagaagg cctgccatac tcatactaga ggcagtcagg agaatactga
    35521 tagttcttgg gagacgggac tcttgaaaga ggagccaggt ctgctggtcg aaatcaaata
    35581 gctttcccca tgaaaaatca ctggtcccaa tgctaataga gagaaagact aggagtagaa
    35641 gtaagccaat taaataatga gaaagtttca taccccgtcc tttcatgtag atttggtatc
    35701 gaaagatatc tgcggatata aatgtaacat tatttttcta atctgtcaat aaaatttctg
    35761 acaatttaat aaatacaaca aggagagagc aacaagactt tctcctttgt tatcctattc
    35821 taaaatgttt ttaccttaat ctgataaaat aatatcttcg agggagtagc tagccgtcca
    35881 atcaagatat tgtttagctt ttgaagcatc tgctaggaca ctggctgggt cactagcacg
    35941 tcgagcaaca atctcgtgtg ggatttttta atttagtaat tcttcagcag ttttaaagat
    36001 ttctttgata gtatagcctt ttttagttcc taagttaaag atttgagaag aactgtcttc
    36061 ttgaaatagg tagttcattc ctttaacatg agcctatgca aggtccaaga cataaatgta
    36121 atctcgaata catgaaccgt cacgtgtatc gtagtcatct ccaaatattt ttaagctatc
    36181 attttgtccc aatgcggtct tgttgatatt tggaatgatg tgagttggat ttttcacacg
    36241 cagaccgttt gaagcatcca tttcagcccc agcaacatta aagtaacgga aaataacata
    36301 tttccagtcg tagcgattgg ccatccagta aatcattcgt tcgcccatca gttttgtctc
    36361 tgcataaggg ttgacagggt cgagcagggt atcttcagtc accggcttgt caatacagtt
    36421 atttccatag agagaagcag tcgaagagaa catgattttt tgaatgccaa cttcagataa
    36481 gactttgaga acttggttca taccagcaac gttggcagtg aagtatttac ttggattttc
    36541 aatactttcg ctcacaacaa tttcacctgc acaatggagg acagcatcaa tctgattttc
    36601 ttctaagtaa gcctttaagg cgctagcatc ataaacatcc agttctttaa agctagcacg
    36661 actatccaca gccgctcgat ttcctgtgga gagattatcg aggacatgca ccttatagcc
    36721 agcatttaaa agagctttaa cggtatggga gccaatgtag ctagtcccac ctgtaacaag
    36781 aattgttttg gtcatgattt tttccttttc tagttttgta ctatagtaaa ttgaaataag
    36841 atatgaacaa ctctattagg aaagtcaaat taatttctag aaatgtttca gcagctacag
    36901 cgtactattc caaactcaac caactatata tttaaagaaa gaagaaaggg aagtcaacta
    36961 ttttctgtaa atttcatgaa aaatccaaac aactttgatg gtgtattgtt tttttgtttg
    37021 gaaataaata ttcgagttaa ttttggaatg tttactagat tttgcactac atgcaagaga
    37081 atactatcct tttctaagat agagcaggac taagatacta acttagaaat ccaccttccc
    37141 actatccttc tcctataaaa agtggtaaaa tggatgaaag aaagaaggaa ctgaaatgac
    37201 aacattattt tcaaaaatta aagaagtaac agaacttgct gcagtctcag gtcatgaagc
    37261 gcctgtccgt gcttatcttc gtgaaaagtt gacaccgcat gtggatgaag tggtgacaga
    37321 tggcttgggt ggtatttttg gtatcaaaca ttcagaagct gtggatgcac cgcgcgtctt
    37381 ggtcgcttct catatggacg aagttggttt tatggtcagc gaaatcaagc cagatggtac
    37441 cttccgtgtc gtagaaatcg gtggctggaa ccccatggtg gttagcagcc aacgtttcaa
    37501 actcttgact cgtgatggtc atgaaattcc tgtgatttca ggttctgttc ctccgcattt
    37561 gactcgtgga aaggggggac caaccatgcc agccattgcc gatatcgttt ttgatggtgg
    37621 ttttgcggac aaggctgagg cagaaagttt tggcatccgt cctggtgata ccatcgtacc
    37681 agatagttct gcaattttga cagccaatga aaaaaatatc atctcaaaag cttgggataa
    37741 ccgctacggt gtcctcatgg taagcgagct agctgaagct ttatcaggtc aaaaactcgg
    37801 caatgaactc tatctgggtt ctaacgtcca agaagaagtt ggtctgcgtg gcgctcatac
    37861 ctctacaacc aagtttgacc cagaagtctt cctcgcagtt gattgctcac cagcaggtga
    37921 tgtctacggt ggtcaaggca agattggaga tggaaccttg attcgtttct atgatccagg
    37981 tcacttgctt ctcccaggga tgaaggattt ccttttgaca acggctgaag aagctggtat
    38041 caagtaccaa tactactgtg gtaaaggcgg aacagatgca ggtgcagctc atctgaaaaa
    38101 tggtggtgtc ccatcaacaa ctatcggtgt ctgcgctcgt tatatccatt ctcaccaaac
    38161 cctctatgca atggatgact tcctagaagc gcaagctttc ttacaagcct tggtgaagaa
    38221 attggatcgt tcaacggttg atttgattaa acattattaa accataaggg aggtggtagg
    38281 gatggtagaa ccaaacctag aaagccttat aaaagatctt tacaatcatg ctcgacatga
    38341 tttgagtgaa gatttagttg ctgctctcct agagactact aaaaaactgc ctactacaaa
    38401 tgagcaattg caggcagttc gtctctcaag cctggtcaat cgtgaattgc tcctaaatcc
    38461 caaacatcca gcacctgagt tgctcaactt ggctcgcttt gtcaaaagag aagaagccaa
    38521 gtacagagga actgcgactt ctgcgcttat gtatgaggaa ctttttaaaa tgctttgatt
    38581 ccattgtgga tcaaagcatt ttttataaga cctatctcgt gagcgttcaa atagtagtaa
    38641 caaggaatca tgagaagtca gccgagacca tagtagtgaa gaaacttctg taatggaagt
    38701 ggagtgaagt gaggaatcat caaacggtag gggataggct gtttgaaggg tgctacgaaa
    38761 aagatagggt aaggtgaaat tatagcggaa tgaaataaga tatgaacaaa ttgattaggg
    38821 aaatcaaatg aatttataga aatcttttag cagtcatggc gtcctattct agtttcaaaa
    38881 tgctataaat acgaacaaat tgattgggaa attcaaatcg ctttctatca atgttttaga
    38941 agatacagtg ccctagtcca acttcaatat actataaaag aacagatgga agcaattatg
    39001 atttacttct atctttaaaa taaatgatct gataggaaaa atgtgtcccc tcataaaaaa
    39061 taggatagta cggatggaag gcttttgtag actggaggac gaaggaattt agaaactctc
    39121 gttaaaagtt agttgagccg gagtatggtg gtgtgaataa ttatcaaaaa ttatttccaa
    39181 atcgaaatag ttgacagtta gaacgatgag tgttacaatt attttattca tttcgatatc
    39241 gaaataaatt ggaggtgtta tgaaagatag tcatttgcta gcccatcata ttcgtttgtt
    39301 gaatgggcgg atttttcaaa agttactgag tcaagatcct gaggctcttt ataggggtga
    39361 acagggcaag attttagcgg ttttatggaa tagtgaaact ggctgcgcaa ctgcgacaga
    39421 tatcgcgctt gcgactgggc ttgcgaataa tacgctgacg actatgataa aaaagctaga
    39481 ggaacaaaag cttgtaattg ttagtccgtg tggaaaagac aagcgtaaga agtatttagt
    39541 tttaacggag ttaggcaagt tccagaaaga agtggggcat cgtgtcagtc agaaattgga
    39601 tactatcttt tacaaaggat tttcagagga agaaattcac caatttgaag gttttcaaga
    39661 aagaattttg gcaaatctga aagagaagga aaatgaggtt tagaatatgt cacaacaagt
    39721 gaaaaatgct cacaacctat acatccatgc cattcaagac ggacgagttg ctgaggctca
    39781 agcccagtct gtaggggata cctatatcca acattcgaca ggtgttcctg acgggaaaga
    39841 aggatttgca gccttctttg cagatttctt tgagcgtcat ccagagcgtc agattaagat
    39901 tgtccgcacc attgaggatg gcaatctggt ctttgttcat gttcatcaat atctgaatgg
    39961 tggagaagct caatgggtga cgacggatac tttccgtgcg gatgagaatg gtcgtattgt
    40021 tgagcattgg gatgtcattg actactatcg aacacctgaa aatgaccaac tagatcaaat
    40081 ttttggagat tttgaaatca aggatttgga caagaaagca gaaaataaaa agctggttcg
    40141 ccgtttcttg acagaaactt tccaaaatgg ggagctagag cagtggagtg attatgtggc
    40201 agacgatttg attcagcata atcatgagat tggacaagga agtgctgctt ataaaaacta
    40261 tgtggctgaa tatagtgtca cttttgactt tgttttccaa ctcttaggac aaggaaacta
    40321 tgtggttagc tatggtcaga ctcagattga tggcgttgct tatgcccagt acgatatctt
    40381 ccgtttagag aacgggaaaa ttgtggagca ttgggataat aaggaagtca tacctaaggt
    40441 agaagacttg actaatcgag ggaagtttta aattgaggac aaagaatgat tgaatacaaa
    40501 aatgtagcac tgcgctacac agaaaaagat gtcttgagag atgtcaattt acagattgag
    40561 aatggggagt tcatggtttt agttgggcct tctgggtcag gtaagacgac catgattaag
    40621 atgattaacc gtctcttgga accaactgat ggaaatattt atatggatgg caagcgcatc
    40681 aaagactatg atgagcgtga acttcgtctt actactggat atgttttaca ggctattgct
    40741 ctctttccca atctaacagt tgaggaaaat attgctctca ttcctgaaat gaagggttgg
    40801 actaaggaag aaattgctca aaaaacagaa gagcttttgg caaaagttgg attaccagta
    40861 gctgagtatg ggcatcgact tccaagtgag ctatctggtg gagaacagca acgggtcggt
    40921 attgtccgag ctatgattgg tcagcccaag attttcctca tggatgaacc cttttcggcc
    40981 ttggatgcta tttcgagaaa acagttgcag gttctgacaa aagaattgca taaagagttt
    41041 gggatgacaa cgatttttgt aacccatgat acggatgaag ccttgaagtt ggcggaccgt
    41101 attgctgtct tgcaggatgg agaaattcgc caggtagcga atcccgagac aattttaaaa
    41161 gtgcctgcaa cagactttgt agcagacttg tttggaggta gtgttcatga ctaatttaat
    41221 tgcaactttt caggatcgtt ttagtgattg gttgacagcc ctatctcaac atttgcagtt
    41281 gtcacttttg accttgttac tagctatttt gcttgcgatt cccttggctg tttatcttcg
    41341 ctatcatgag aagttggcgg attgggtctt acagattgca gggattttcc agaccatccc
    41401 gtctctggcc ttgttgggac tctttattcc cttgatggga attgggactt taccggcatt
    41461 gacagctcta gtgatttatg cgatttttcc gattttacaa aatactatta ctgggctgaa
    41521 gggaattgat ccgagtcttc aagaggctgg gattgccttt gggatgacca gatgggagcg
    41581 tctcaagaag tttgaaattc cacttgccat gcctgttatc atgtctggaa ttcggacggc
    41641 agcggtcttg attatcggta cggctacctt ggcgaccttg attggggcag ggggactggg
    41701 ttcctttatc ctgttgggaa ttgaccgtaa taatgccagt ttgattttga ttggggccct
    41761 ttcttctgca gtgctagcta ttgcctttaa cttcctacta aaagtaatgg aaaaagcgaa
    41821 attgcggacg attttctctg gttttgcctt ggtggcttta ttactgggtc tgtcttatag
    41881 tccagccctt ttggctcaaa aagagaagga aaacttgatt attgctggga aaataggccc
    41941 agaaccagaa attttggcta atatgtataa attgctgatt gaagaaaata ccagcatgac
    42001 tgcgactgtt aaaccgaatt ttgggacgac aagtttcctt tatgaagctc tgaaaaaagg
    42061 tgatattgac atttatcctg aatttaccgg tacggtgact gaaagtttgc ttcaaccatc
    42121 acccaaggtg agtcatgagc cagagcaggt ttatcaagtg gcgcgtgatg gcattgccaa
    42181 gcaggatcat ctagcctatc tcaaacctat gtcttatcaa aatacctatg ctgtagctgt
    42241 tccgaaaaag attgctcaag aatatggctt gaagaccatt tcggatttga aaaaagtgga
    42301 agggcagctg aaggcaggct ttacgcttga gtttaacgac cgtgaagatg gaaataaggg
    42361 cttgcaatca atgtatggtc tcaatctcaa tgtggcgact atgcagccag ctcttcgtta
    42421 tcaggcaatt cagtcagggg atattcaaat cacggatgcc tattcgactg atgcggaatt
    42481 ggagcgttat gatttacagg tcttggaaga tgacaagcaa ctcttcccac cttatcaagg
    42541 ggctccactc atgaaagaag ctcttctcaa gaaacaccca gagttggaaa gagttcttaa
    42601 tacattggct ggtaagatta cagaaagcca gatgagccag ctcaactacc aagtcggtgt
    42661 tgaaggcaag tcagcaaagc aagtagccaa ggagtttctc caagaacaag gtttgttgaa
    42721 gaaatgatgg gacagagact ttaaacatac tgaactcaac ttccttaaac gactagataa
    42781 aagaatgctc agacaatttc gtctgggctt ttttgatgtg agaatgactg aatgtcactt
    42841 aaaatggaaa gaaagagaaa attttcatga ttttctaaaa ttttactgta aagacagttg
    42901 actattcata aaataggtgt ataatatttt gtgaactact taacaaataa gaggtttcag
    42961 ctcatgtcga ctaaggttag aaatcttgtg tataggcagt tcattatcta atagagcgtt
    43021 gcgtccgaaa gtctatccag acacggctct ttaaaaacaa aaggagaaat gatgcatact
    43081 tatttgcaaa agaaaattga aaatatcaaa acaaccctag gtgaaatgtc aggtggttac
    43141 cgtcgtatgg ttgcggctat ggctgattta ggattttcag gaactatgaa ggctatctgg
    43201 gatgacctct ttgcccatcg tagttttgcc cagtggattt atttgctggt tttaggaagt
    43261 tttcctctct ggctggagtt ggtttacgaa catcgtattg ttgactggat tgggatgatt
    43321 tgtagcttga cagggattat ctgtgtaatc tttgtatcgg aaggtcgagc aagtaattat
    43381 ctttttggct tgattaactc tgttatttac cttattttgg ccctacagaa aggcttttat
    43441 ggtgaggtgc tgacgacact ttacttcaca gtcatgcagc caattggact tctagtttgg
    43501 atttatcagg cacagtttaa gaaggaaaag caggagtttg tcgcgcgtaa actggacggc
    43561 aagggctgga caaagtatct ttccattagt gtgctttggt ggttggcctt tggcttcatt
    43621 tatcagtcta ttggtgccaa tcgtccctat cgtgattcaa tcacagatgc aaccaatggg
    43681 gtagggcaaa tcctcatgac agctgtttac cgtgaacagt ggatattctg ggcggctacc
    43741 aatgtttttt caatctatct ctggtgggga gaaagcctgc aaattcaagg gaaatatcta
    43801 atttatctca ttaacagtct agttggttgg tatcaatgga gcaaggcagc taagcagaat
    43861 actgatttac ttaactagga aaagatgttt gaaagtgctg ttttgagatt tcgattaaaa
    43921 cagatatagt tgataatcaa ggatttatag tatgaaaaag aggatcggcg ggtcctcttt
    43981 tgttgttgaa aagataaaaa actcagtaac ctagaaataa gacaactgag ctttactcta
    44041 tattcaattt ttaggaatga gaaggtctag ataaaattgg acaacttcct ggcctgtgaa
    44101 atcttgacct tttttgagcc accaggtcaa tgtctcgata aagttggaca cgaccaagtg
    44161 ttggaggtaa gaagtaggca tattagggtg ggcttctttt aaattatcag ctagcacgga
    44221 atagacatgg tgttctagct ctttatggag ttgacggagg aagtagtcat ttttggaaaa
    44281 tagcagactg gtgatatggt cttggttttt atgaaaatgg agaaagaggt gggcgaggta
    44341 gtcctcggtt gaaatggctt gctctctttc aaaaagatga tggaagaggt agcggcagag
    44401 ctggtccaga agaagctcct tactttcata gtgacagtaa aaggtggatc ttcccacatc
    44461 tgcgagatca atgatatcct gaacagtagt ggcctcgtag cccttagcat tcaaaagttg
    44521 tataaaagct tgatagatgg cttttttggt tttgctgata cggcggtcaa tgttagtcat
    44581 atggacactt aaggcaaatt gttcagaact gaataaagct gacgttttgc ttctatcctt
    44641 tctttgagtt ttagtggata atgataatga acaaggtgtt cataaatcta ttataacaaa
    44701 ggaatgagaa atatgaaggc aaaatatgct gtttgggtgg cttttttctt aaatttgact
    44761 tatgccattg ttgagtttat tgcaggtgga gtatttggtt ctagcgctgt tcttgctgac
    44821 tctgtgcatg acttgggaga tgcgattgca attggaatat cagcttttct agaaacaatc
    44881 tccaatcgtg aagaagacaa tcagtacacc ttgggctata agcggtttag cctgctagga
    44941 gccttggtaa cagctgtgat tctcgtaacg ggctctgttc tagtcatttt ggaaaatgtc
    45001 acgaagattt tgcatccgca accagtcaat gatgagggga ttctctggtt aggaattatt
    45061 gcgattacta tcaatctgtt agcgagtctg gtggttggta agggaaagac aaagaatgag
    45121 tctattctga gtttgcattt tctggaagat acgctagggt gggtagctgt tatcctgatg
    45181 gcgattgttc ttcgatttac ggactggtat atcctagatc ctcttttgtc ccttgtcatt
    45241 tctttcttta ttctttcaaa agcccttcca cgtttttggt ctacactcaa gattttcttg
    45301 gatgctgtgc cagaaggtct tgatatcaag caagtaaaga gtggcctgga gcgattggac
    45361 aatgtggcca gccttaatca gcttaatctc tggactatgg atgctttgga aaaaaatgcc
    45421 attgtccatg tttgtctaaa agaaatggaa catatggaaa cttgtaaaga gtctattcga
    45481 attttcctaa aagattgtgg ttttcaaaat attaccattg aaattgatgc tgacctagaa
    45541 actcaccaaa cccataagcg aaaggtgtgt gacttggaac ggagttatga gcatcaacat
    45601 tagaaaaaag tgaaaaatac ttgggtacta tcttatttgg aatagagtaa tttctttatt
    45661 atttaaatat ttcaaaaatt ggtaagagaa gagcattgta taaactccgg atatatgatt
    45721 gttaatgata aaaatttttc gattagatac aaaatgcttg acttggagtc aactcaaagt
    45781 tatataataa gataagtgag ttagaatagc gtgaattcag tgaatgaaat gagaggaggt
    45841 tagcgtgtga atattaaatc tgccagtgat ttgttgggaa tttcagcgga tacgattcgg
    45901 tattatgaac gggttggtct tgtgccaccg attactcgta ctgctactgg gattcgtgat
    45961 tttcaagatc aggatatcga agcgctggaa tttattaagt gttttcgttc ggcgggtgtc
    46021 tctgtagata gtttagttga ctatatgtcg ctctaccaaa agggagatga aacgagagag
    46081 gagaggcttg gtattttaga agaggaaaag caaaaattag aggagcgctt gtctcagcta
    46141 cagacagctt taaatcgttt aaatctcaaa attaaacttt ataaggaagg aaaattttaa
    46201 atgaaatcag cagtatatac aaaggcaggt caggttggac ttgctagcat tgaacgtccg
    46261 caaataatag aagcggatga tgtgattatt cgtgtggttc gtgcgtgcgt ttgtggttca
    46321 gatttatgga ggtaccgtaa tccagaaacg aaagctggac ataaaaatag tggacacgaa
    46381 gcgattggga ttgttgaaga agctggggaa gccattacga cggtgaaacc aggtgatttt
    46441 gtgattgtcc cttttacaca tggatgtggt gagtgtgatg cctgtcttgc tggatttgac
    46501 ggttcttgcg acaatcatat tggcaataat ttggggggtg attttcaggc agaatatatt
    46561 cgcttccact atgcaaactg ggcgctggtt aaaatccctg gtcaaccttc tgattataca
    46621 gaagggatgc tcaagtccct tttgactctt gcagatgtca tgccgacagg ctatcatgca
    46681 gcgcgtgttg caaatgttca aaaaggggac aaggttgttg ttatcggtga tggggctgtt
    46741 ggtcaatgtg ctgtcatcgc ggctaagatg cgtggagcat cacaaattat ccttatgagc
    46801 cgtcatgaag accgtcaaaa gatggctatg gagtcaggtg cgacagctgt tgttgcagaa
    46861 cgtggtcaag aaggaattac caaggtgcgt gaaatcctcg gtggaggagc agatgcagca
    46921 cttgaatgtg ttggtacgga ggctgctata gaacaggcgc taggtgttct tcataatgga
    46981 gggcgtatgg gctttgtagg agtcccacac tataataatc gtgctcttgg ttcgacattt
    47041 atgcaaaata tctctgtagc aggtggggca gcttctgcta caacatacga taagcaattt
    47101 ttactaaaag ccgtccttga tggtgatatc aatccaggtc gcgtctttac ttcaagttat
    47161 aaactggaag atatcgacca agcctacaaa gatatggatg aacgtaagac cattaagtct
    47221 atgattataa tcgaataaaa aacgaatagg agttctaaaa ctcctattcg ttttttatgt
    47281 tatcctattc ttgatttagg gtactttctc ttaatgtcag tctggttccc agcatggtca
    47341 ggctagggat tttccgaccg tggaggactt ccttgttaag aatatccata cctgctcggc
    47401 ccatttcttc agtataaact gtaatactag agaggggagg atagacctgt ttggtcagac
    47461 tagtgtcgtt aaaggaaatg aggctgacgc gatctggcag gttgattcca gcttcttgga
    47521 gggcacggag ggcaccgata gctaaactat cgctggctgc gaaaaatgct ggcggaagtt
    47581 ggtctcccaa gctctgaatg gcctccttca tcaagtcata gccagactgg gcagtaaagt
    47641 ttccttgaaa gatcagttca tcatgataga ttccttttgc ttgactgtag tttctgaaat
    47701 tttccagccg cttatcctca atgatttctt cttggtctgt tgtttcttca aggcctgtta
    47761 gaatcccgat acggtccatt ccttgactga ggaaataatc gacaacctgt ttcatagcag
    47821 tgtaaaaatc cgtgataata caggtatgtc ccagggaaag tgtatcgctg tctagaaata
    47881 caagaggctt ttggtattct tcaaaggcag aaatctgagc tcgactaaac tttccgatgc
    47941 agagaatccc aatcacttcc tcgcttaggg taaaagggtg gtcattaaaa tagcgcaaga
    48001 tatcgtagtc caactcttgg gctctttttt ctattcctag gcgaatctgg tagtagtaga
    48061 ggtcgtctag ctccccttgt tcgctgaccc attgaataat ggcaatcttt tgcttgggtt
    48121 tgtgggactc gcctgtcttg aggtgcttgg tgtagcccag ctcttcagca acggttaaaa
    48181 tacggtgtct ggtttcttct gtaacagata ggctctggtc gcggttgagg acacgggata
    48241 cggtcgcgat tgagacagag gctagctgtg caatgtcttt taaggtagcc ataaatcctc
    48301 cttgattagg ttagtatatc atatttttct tctttttact gatattttag taaaatttta
    48361 gtaaaaagga ttgaccttgg gaaattcctt ggatacaata gaaagaaaac gattacacgt
    48421 taagatggct taacggacag tcaaaggaga attcatatgg cacaacatct tactactgaa
    48481 gtccttcgca aagactttct tgctgttttt ggtcaagaag cagaccaaac cttcttttca
    48541 ccaggccgta ttaatttgat tggtgaacac acagactaca acggtgggca cgtttttcct
    48601 gctgctattt ccttgggaac ttacggtgca gctcgtaagc gtgacgacca agtcttgcgt
    48661 ttctactcag ctaactttga ggacaagggc attatcgaag tgcctctcgc tgacctcaag
    48721 tttgaaaaag agcacaactg gaccaattat ccaaaagggg ttcttcattt cttgcaagaa
    48781 gctgggcacg tgattgacaa aggttttgat ttttatgttt atgggaatat cccaaatggt
    48841 gctggcttgt cttcttcagc atccttggag ctcttgacag gagtcgtggc agagcatctc
    48901 tttgatttaa aactagaccg tttggatttg gttaaaatcg gaaaacaaac agaaaacaac
    48961 tttatcggag tcaactctgg tatcatggac cagtttgcta ttggtatggg ggctgaccaa
    49021 cgtgctattt acttagatac caatacttta gaatacgact tggtgccact tgatttgaag
    49081 gacaatgtcg ttgttatcat gaacaccaac aaacgccgtg aattggcgga ctctaaatac
    49141 aatgaacgtc gtgctgagtg tgaaaaagca gtggaagaat tgcaagttgc cttggatatt
    49201 cagaccctgg gtgaattgga cgagtgggcc gttgaccaat atagctattt gattaaagat
    49261 gaaaatcgtt tgaaacgtgc tcgccatgct gtgcttgaaa accaacgtac ccttaaagct
    49321 caagcagccc ttcaagcagg tgatttggaa acatttggtc gtttgatgaa tgcgtcacac
    49381 gtttctctgg agcatgatta tgaagtaact ggtttggaat tggatactct tgttcacaca
    49441 gcttgggcac aagaaggagt tctcggtgct cgtatgacag gggctggttt tggtggctgt
    49501 gccattgcct tggttcaaaa agatactgtt gaggccttta aggaagctgt aggcaaacac
    49561 tacgaggaag tagttggata cgctccaagc ttctatatcg ctgaagttgc aggtggcact
    49621 cgcgtccttg actagtcaaa aggaggctct atagtgatct tagtagataa atttgtaaca
    49681 catgtcattt ctgaaagttc atttgaggaa atggatcgaa tctacctgac caaccgtgtt
    49741 ttggcacgag tgggagaagg tgttttggaa gttgagacca atctggataa attgattgac
    49801 ctcaaggacc agctagttga ggaagccgtt cgattagaga tgattgagga tagtcagact
    49861 gcgcgtgaaa tccttggtac tgaactgatg gacttggtga ctccttatcc gagtcaggtc
    49921 aatcgtgact tctgggaagc ctatgtccac tctcctgagc aagcgataga ggatttttat
    49981 caactcagtc agaaaaatga ttacatcaaa ctcaaggcca ttgctaaaaa tatcgcttat
    50041 cgtgttccat ctgattatgg agaacttgaa attaccatca atctctctaa gcctgaaaag
    50101 gatccgaaag agattgcggt agccaagttg gtgcaagcta gtaattatcc tcagtgtcaa
    50161 ctttgtttag agaatgaggg ttaccatggt cgggtcaacc acccagctcg cagcaaccac
    50221 cggattatcc gttttgaaat ggttggtcag gaatgggggt tccagtattc gccctatgct
    50281 tactttaatg agcattgtat ctttttagat ggccagcatc gtcccatggc cattagtcgt
    50341 cagagttttg aacgtctgtt ggctatcgta gagcagtttc caggatattt tgctggatct
    50401 aatgccgacc tgccgattgt ggggggctct attctaactc atgatcatta tcagggaggc
    50461 cgtcacgtat ttcctatgga attggctccc ttgcaaaaga ccttccgatt tgctggtttt
    50521 gagcaggtca aggctggaat tatcaagtgg ccaatgtctg tcctacgctt gacttcggat
    50581 tccaaagagg atttgattaa cttagctgat aagattttcc aggaatggcg tcagtattca
    50641 gattctagtg tgcagatttt agcagagaca gacgggacac cgcatcacac catcacacca
    50701 atagcgcgta agcgtgatgg acagtttgag ttggacttgg tcttgcgaga caatcagact
    50761 tcagcagagc atcctgatgg catctatcat ccccacaagg atgtccaaca tatcaagaag
    50821 gaaaatatcg gcttgattga ggtcatgggc ttggcaatct tgccaccacg tctgaaagaa
    50881 gaagtagagc aagtcgctag ctatcttgta ggagaagctg ttacagttgc cgattatcat
    50941 caggagtggg cagaccaact caaatcccaa catccagacc taacggataa agaaaaagcc
    51001 cttgcaatcg tcaaggactc tgtgggtgct atctttgtgc gtgtacttga ggatgcagga
    51061 gtctacaagc agacagaaca agggcagaca gcctttatgc gctttgtgga acaggtcgga
    51121 attttactag actaggagct ttctccttgc acagtcctat aaaaagtagt atcatagtgt
    51181 cgtttgaaat atcaggagga aacgatgaaa gactttcatt ttgacgctat atctgccttt
    51241 gaaagttacg aaattgaaaa aatgagagat ggtcacgttg tggtgacgac caaagtagtg
    51301 aactcatcgc tcaactacta tggcaatgcc catggtggct atctattcac gctatgtgac
    51361 caaatcagtg gtttggtggt tatctcgctg ggacttgatg gggtgacact ccaatcctct
    51421 atcaactacc ttaaggcagg aaaactcgac gatgtattga ccattaaagg agaatgtgtc
    51481 catcaaggtc gtacaacctg tgtgatggat gtggatatca ccaatcaaga gggcagaaat
    51541 gtctgtaagg caacctttac catgtttgtc acaggccaaa ggtctgagga aagacgggta
    51601 agtatataaa gaaaggtgag tgggataaat ttatctcact catttttaat ttatgagata
    51661 tgttagaagg aaatataaaa gagagtgatg aaatacaaat gtaataggta catatatgtg
    51721 gtatactagt tatagtagat tttaattgct tatatcgagt gagttctcat attagtgagg
    51781 aatttttaaa tggaattaca ctttaattta gaattagtag aaacctataa aagtaatagc
    51841 caaaaggcac gtatcttaac ggaggattgg gtttatcgtc agtcttattg ccctaattgt
    51901 gggaacaatc ccttaaatca ttttgaaaat aatcggcctg tagcagattt ttactgtaat
    51961 cattgtagtg aggagtttga actaaagagc aaaaaaggaa atttttcatc aacaatcaat
    52021 gatggtgctt atgcaacgat gatgaagcgt gtgcaggcag ataataatcc taatttcttt
    52081 tttttaactt acacaaaaaa ttttgaggta aataactttc ttgtccttcc gaagcaattt
    52141 gttacaccga aatcgattat tcaaagaaaa ccacttgcac caactgctag acgagcaggt
    52201 tggattggtt gtaacattga tttatcacaa gtaccttcta aaggaaggat atttcttgtg
    52261 caagatggac aagttagaga tccagaaaaa gttacaaaag aatttaagca aggtttattt
    52321 ttaaggaaga gctctctgtc atcaagaggt tggacaatag aaattctaaa ttgtatagat
    52381 aagatagagg gttcagaatt tacccttgaa gatatgtatc gttttgaaag tgacctaaaa
    52441 aatatctttg ttaagaacaa tcatatcaaa gaaaagatta ggcaacagct tcaaatatta
    52501 agagacaaag aaataataga atttaaaggt agaggaaagt atcggaaatt atgaaaacga
    52561 aacaacttgt tgcatcagaa gaggtgtatg atttcttaaa agtcatctgg cctgattatg
    52621 aaactgaaag ccgttacgat aacctaagtt taatcgtctg taccttatca gatcccgatt
    52681 gtgtgagatg gttatctgaa aatatgaaat ttggtgacga aaaacaacta gctttgatga
    52741 aggaaaaata tgggtgggaa gtaggagata aattgccaga gtggctacat agctcctatc
    52801 atagattatt gttaataggt gaattattgg aaagcaatct aaaactgaaa aagtatacag
    52861 tagaaattac agaaacttta tcacgtttag taagtataga ggctgaaaat ccagatgaag
    52921 ccgaacgact tgtaagagaa aagtataaga gttgtgaaat tgttcttgat gcagatgatt
    52981 ttcaggacta tgacactagc atatatgaat aggtagatgt ttttattttg tcacacaaaa
    53041 aagaggctcg cacctctttt tcttatttct ttttatgatt taatacggca ttgaggacaa
    53101 tagcgagtag gctggctacg acgattccgt ttgagaagaa catttggaag gctgtcggca
    53161 tgctgacaaa gagattactg ttgttgagac cgacacctgc agcgattgaa acagctgcga
    53221 taaggaagtt gtgttcattg ttagcaaagt caactcgggc gaggatttgc atcccttgaa
    53281 tagatacaaa accaaacatc accagcatgg caccgccgag gacggagctt ggaatgattt
    53341 gggcaagggc accaaactta ggaagcagtc caaggagaac caggaaacca gctgcgtagt
    53401 agattggcag gcgttttttg atgcctgaca atttaaccaa accaacgttt tgtgaaaatc
    53461 cggtgtaagg gaaggtgtta aagattcctc cgagaagtac cgccaaacct tctgcgcggt
    53521 aaccgttgcg aaggcgcgtg ctgtcgattg gatcttttgt gatatcagac aaggctagat
    53581 aaacaccagt tgactcaacc atagacaccg ttgcgatgat acacatcatg acaatagatg
    53641 agatttcaaa ggttggcatc ccaaagtaga gtggagttgg gacatggaca agtggagcta
    53701 ccgcaacagg agagaagtcc accaagccca tagtagcagc aatggcagtt ccaacaacca
    53761 gaccaatcaa aatagagata gacttgataa atcctttggt aaagatgttg atcaagagga
    53821 taatcagaac agtaatagct gcaagcaaga gactttgacc agttggctct ggaacgttat
    53881 ttcccatatt tccaatagcg acagggatca aggttaaacc aatcgtggta ataacagatc
    53941 ctgttacgat agatgggaag agattggcta cttttgagaa gatgcctgaa acaagaacca
    54001 cgtaaatccc agatgcgata agggcaccaa acatagcgcc attaccatgg ctttgcccaa
    54061 tcataatcaa gggagcgacc gactggaatg caactccaag aacgactggg agtccaatcc
    54121 caaagtattt gttgagttgg agttggagga aggttgccac cccacacatg aagatatctg
    54181 tagaaatcag gtaggtcaac tgctcagctg aatagccaag ggctgtcgca atcatgatgg
    54241 gaaccaggat agatcctgag tacatggcta gtaagtgctg caagcccaga acggctgctt
    54301 gcgagtgttt ttcttgagtt tgcattagag atctgcctcc ttaaatacga cctgaccatt
    54361 ttcaaaacga tccaagcgag caagtgatag gacagggtag cctgcttttt caagcaaatc
    54421 acgaccatct tggaaggatt tctcaatcac gataccgata gcttggactg tggcaccggc
    54481 ctgttcgatg atttgaatca agcctttagc agcttggcca ttagcaagga aatcgtcgat
    54541 aatcaaaacc ttgtcctctg gtgagaggaa ttttccagcg atagaaacag tgctggtcac
    54601 ctgcttggta aaggagtaga cttgagcagt taagatgcct tcgttcatgg tgatgttctt
    54661 agcttttttg gcgaaaatca tgggaacgtt taaggcttca gctgtaaaaa cggctggggc
    54721 aatacccgac gcttcaatgg ttacgacctt ggtaatgcca gtagcagcaa atttttccgc
    54781 aaaaacctta ccaatctctc gcatcaagct aaagtcaact tggtgggtta aaaaggaatc
    54841 taccttgagg atgttatcac ccaagatatg cccatccttg aggatgcgct cttctaataa
    54901 tttcataaga cctcctaaag tctaaaagtt aatttacttg ttgtttaaat atttctatag
    54961 tgatcccttt tgctaatact atatatttga taaaactatt acgagcgaag cgagtcttat
    55021 caaatatttc ccgttgtagt ggtatcatag acaataatct tgttattgtc tatgacggga
    55081 tttttgagag taaaatagtt cggggaacta ttttagccta agcctagaaa tgaaagagct
    55141 aggggctcaa aaattaggga tgaaattccc tggattcctg aaattattca caggataatt
    55201 tcacctcccg tccgcactaa ttaagggaaa tattaaaaat attcaaaaaa gacctactta
    55261 atctctaagt aagtccccta aatagacatg gcaaaaacgg ccatatctca ctgctgactt
    55321 acttattgtt aggtgttccg gcaccttgta gaaacgtcgt gccaattcac gacataaaca
    55381 agtaaaacga tattcaattt taaataggct tgagccaatg tttttatttt acactaaata
    55441 actttagaaa tcaactattt tgttagtgtt ttggtttaaa aagcgaacaa aaataagaga
    55501 gggtgaacaa aaactccatt gtaagctaac atttatacta aatgaaaatc aaagagcaaa
    55561 ctaggaagct atccacaacc tcaaaacact gttttgaggt tgtggataga attgacagag
    55621 tcagtatcat atacctacgg taaggcgacg ttgacgtggc ttgaagagat tttcgaagag
    55681 tattagaaga tttttccatc ataaaaggca tactatcaag tttttagaca cctgacaata
    55741 tgcctttttc taactttaaa gacttttccc aatttttatt attctactcg ctaaatctta
    55801 aaaaatagcc atctggatcc aaaactgcaa atttatgagg atagatatag ggatcactga
    55861 cacgaaactt tcttttggtc aagagacgat aaataggata gtttgcctcc atcacttttt
    55921 gatagagttt tggaacatcc tttatgccaa aggagagatt gactccacga ccaaaggggt
    55981 aggtcagttc agctagttga tcctttgttc cctcctctaa cattagttga cactcttcaa
    56041 gagaaagaga aagttttctt ctggacgtta gtattcaatc ctaaaaccca gtaaaccaca
    56101 gtagaaggac cgggactgtt cgatattcga tacaagaaac tcgggaatga ccgcattgta
    56161 gtccatatag aaaatcctta caagtcaatt tccaagacaa tcggtgtatg gtcttggcga
    56221 gcacctgagt caatcatatc agatttagtg accttgtcag cgatacggtt acttgtgagc
    56281 cagtagtcga ttctccagcc tgtattgttg attttagaag ttttgctgcg ttgtgcccac
    56341 caagtgtagc gttcaggaac atcgccatga acatggcgga aggtgtctgt aaatccagtt
    56401 gccaaaaggt tggtaaatcc agcacgttcc tcgtcagtaa atccaggtga acggcggttg
    56461 ctagcaggat ttgcaaggtc gatttcattg tgggctacgt tgtagtcacc ggtcgcaagg
    56521 actggttttt ctttgtctag ttcagccaaa tactcagcat atttaacatc ccagacttgg
    56581 cgttcttcca agcgtttgag accgtcacca gcgtttggag tgtaaacttg ggttacgaaa
    56641 aatgcatcaa attctagagt gatgatacgg ccttccaagt ccatggtaga aggggcaccg
    56701 atttctggaa aactgatcgt aggcgtaagt tctttcttat aaaggaacat ggttccagca
    56761 tagcctttac gggcaggctc ttgggaagag cgccatgtgt tttcgtagcc tgggaagagt
    56821 tcttctaaaa tttccacgtg tttctttgta ggtcctttgg cagaaagctt ggtttcttgg
    56881 atagcaatga tatcagcatt ttcagcgacc aaggtttgta ggacttcttg ggacaatttg
    56941 gcacgagctg agtcactagt tagggcagcg tttagggaat caatattcca tgagataagt
    57001 ttcataaagt tacctttttc attcagatta tagattttat tataccaaaa aaagatctat
    57061 ttccccaacg tatggtttga aaaattactc tctttcgttt ataattaaga atgattttat
    57121 gaaagggagt gaaaatatat gaaattctac tcttatgact atgtactcag ccaaatcggt
    57181 cagcaaaatg gtatcatggt tggctttggg attgttctat tagctgtgac agtttttttt
    57241 gctttcaagg cataccatga taaaaaggga accgaatttc gtgagttggt catgatttca
    57301 gctctggcct tatttagctc tgcttttggt cagcatcacg acttatcaaa acaatcaagt
    57361 ttctaacaat aaatttcaaa cttcacttca tttcatcgag gttgtttcca aagatttggg
    57421 agtagacaag tcagaagtct atgttaatac ttccacaaac acagatggcg cacttatcaa
    57481 ggtgggagat cgctattatc gtgccctaaa cggaagtgag ccagacaagt acctgttaga
    57541 gaaagtcgaa ttgtataaga cagacgcaat tgaactggtg gatgtgaaca aatgacactt
    57601 aattatatcg aaattttaat caaactggtc ttgactctca aatggctcaa caacaatgtt
    57661 cactttgtga aacgtttgat tgatggtaag ccaactctcc ttatcaaaaa tgggaatatt
    57721 gacccagaag cctgtcgttc agttggtttg tctgcatcgg atgtagccct caaacttcgt
    57781 agccaaggga ttttccagat gaagcaagtc aaacgagctg tgcaagagca aaatgggcaa
    57841 cttatcgttg tgcaaatggg agatgaaaat cctaagtatc cagttgtgac tgacggtgtg
    57901 attcaagtag atgtcttgga atcgattggt cgtagcgaag agtggttgct tgataacctc
    57961 agtaaacaag ggcatgacaa tgtagccaat atctttattg ctgaatatga caagggtgct
    58021 gttacagtcg taacttatga aaaagaaaaa cctggggtct tgtactcttc gaaaatctct
    58081 tcaaaccgcg tcaacgtcgc cttgccgtat gtaggttact gacttcgtca gttctatcta
    58141 caacctcaaa gcagtgcttt gagcagcctg cggctagttt cctagtttgc tctttgattt
    58201 tcattgagta ttggcctcag gtttccattt gcaatcagaa agggatttta tgtccattat
    58261 tcaaaaactt tggtggtttt tcaagttaga aaaacgccgt tatctagtcg gaattgtggc
    58321 cctggtcttg gtttccgtcc tcaatctcat tcctcctatg gttatggggc gggttattga
    58381 tgccatcaca tcggggcaat taacccagca ggacctcctt cttagcctat tttacttgct
    58441 acttgcagcc tttggtatgt actatttgcg ctatgtgtgg cgtatgtata tccttgggac
    58501 ctcttattgc ttgggacaga tcatgcggtc tcgcttgttt aagcatttca caaaaatgtc
    58561 gtcagccttt tatcaaacct atcggacggg tgatctgatg gcacacgcaa ccaatgatat
    58621 caatgccttg actcgtttag caggtggcgg tgtcatgtct gcggtggatg cctctatcac
    58681 ggctctggtg actttgttga ccatgctctt tagcatctca tggcagatga ctcttgttgc
    58741 cattctcccc ctacctttca tggcctatgc gactagtcgc ctagggagaa agactcataa
    58801 ggcctttggc gaatcccaag ctgctttttc tgaactcaat aacaaggtac aggagtccgt
    58861 atcaggtatc aaagtgacca agtctttcgg ttatcaggca gacgagttga agtcttttca
    58921 ggcagtcaat gaattaacct tccaaaagaa cctgcaaacc atgaaatatg atagtctctt
    58981 tgaccctatg gttctcttgt ttgttggttc gtcctatgtt ttaacgcttt tggttggctc
    59041 cttggtggtt caggaagggc agattacagt tgggaatcta gtcaccttta tcagctattt
    59101 ggatatgctg gtctggcctc ttatggccat cggcttcctc tttaatacta ctcagcgagg
    59161 gaaggtttct taccagcgga ttgaaaatct tttgtctcag gaatctcctg tacaagaccc
    59221 ggagtttcct ctggatggta ttgaaaatgg gcgtttggag tatgccattg acagctttgc
    59281 ttttgaaaat gaggaaacac tgacggatat tcactttagt ttggcaaaag ggcaaacact
    59341 gggcttggtt gggcagacag gctctgggaa aacgtcctta atcaagctcc tcttgcgtga
    59401 atacgatgtg gataagggcg ccatttatct aaacggtcac gatattcggg actatcgtct
    59461 gacagacctt cgcagtctca tgggctatgt tcctcaggac cagtttcttt ttgcgacttc
    59521 aatcctagac aatatccgct ttggcaatcc taacttgccc ctttcagcgg tcgaggaagc
    59581 tactaagcta gcccgagttt accaagatat tgtagacatg cctcaaggat ttgatacgct
    59641 gattggtgaa aaaggagtca gtctttctgg tggtcaaaag caacggttgg ctatgagtcg
    59701 ggctatgatt ttagaccctg atatcttgat tttggatgat tccttatccg ccgtagatgc
    59761 caagacagag tatgcgatta tcgacaacct caaggagacg cgaaaggaca agacaaccat
    59821 tatcactgcc catcgcctga gtgcagttgt ccatgcagat ttgattttag tcctgcaaaa
    59881 tggtcaaatt atcgaacgag gcaggcacga agacttgcta gctttggatg gctggtatgc
    59941 ccaaacctac cagtctcagc agctggaaat gaagggagaa gaagatgcag aataaacaag
    60001 aacaatggac tgtattgaag cgcttgatgt cctatctcaa gccttatgga ctccttacct
    60061 ttttggcact cagttttctc ctagcgacga cggtcattaa aagtgtcatt ccccttgtgg
    60121 cttcccactt tatcgaccag tatctcagca atcttaacca actagccgtg accgttttgc
    60181 tggtctacta tggtctctac atcctacaaa ctgtagttca gtatgtcggc aatcttctct
    60241 ttgcgcgcgt gtcttacagt attgttaggg atattcgtcg ggatgccttt gccaatatgg
    60301 agaaactggg catgtcttac tttgacaaga cgccagcagg ttctatcgtt tctcgtttga
    60361 ccaacgatac cgagacgatt agtgatatgt tttctgggat tttatccagc tttatctcag
    60421 cagtttttat ctttctgaca accctttata ccatgttggt gctggatttt cgtttgacgg
    60481 ctttagtctt gctctttctc cccttgattt tccttttggt caatctctat cgaaaaaagt
    60541 cagtgaaaat catcgagaaa accagaagtc tcttgtcaga tatcaatagt aagctggcag
    60601 agaatatcga gggaatcagg attattcagg cttttaatca agagaagcgc ctgcaggcag
    60661 aatttgatga aatcaaccaa gagcacttgg cctatgccaa ccgttctgta gccttggatg
    60721 ccctcttttt gagacctgcc atgagtttgt tgaaacttct aggttatgct gtcttgatga
    60781 cctattttgg ctatcgtggt ctttctatcg ggataacggc cgggaccatg tatgctttta
    60841 tccagtacat caaccgcctc tttgaccctt tgattgaggt gacgcaaaac ttttcaacac
    60901 tgcaaacgtc tatggtttct gcaggccgtg tctttgcctt aatcgatgag aggacctatg
    60961 agccccttca agaaaatggg caagccaaag tcaaagaagg caatatccgt tttgaacatg
    61021 tgtgtttctc gtatgacggt aaacatccga ttctggatga catttctttc tctgttaata
    61081 agggtgaaac cattgccttt gtaggtcata caggttcagg gaaatcgtct attatcaatg
    61141 tcctcatgcg cttttatgaa ttccagtcag ggagagttct cttggatgat gtggatatca
    61201 gggatttcag tcaagaagag ctgagaaaaa acatcggttt ggttttacag gaacccttcc
    61261 tctatcatgg aactattaag tccaatatcg ccatgtacca agaaatcagt gatgagcagg
    61321 ttcaggctgc ggcagccttt gtggatgcag attcctttat tcaagaactt cctcaggggt
    61381 acgactcccc tgtttccgag cgtggttcga gcttctctac tgggcagcgc cagcttcttg
    61441 cctttgctag aacagtcgcc agccagccta aaatcctgat tttggatgaa gcgacagcca
    61501 atattgactc tgaaacagaa agtttggttc aagcttctct ggcgaagatg agacagggcc
    61561 gaacaactat tgctatcgct caccgccttt ctactattca agacgccaac tgcatctatg
    61621 tcttggataa gggacgcatt atcgagagtg gaacccatga ggaactcttg actctgggag
    61681 gaacctatca caagatgtat agtttgcagg caggggccat ggcctatact ctttgaaaat
    61741 ctctttaaac catgtcagct ttatctgcaa tctcaaagct gtactttgat tttcattgag
    61801 tactagaagg aaatccttca aattacagat ttctttcacc gccttttcca ttttgtggta
    61861 taatgaaaaa tgttgacaaa tagtataata aaaacaaagg agaacagcat gctgaaatgg
    61921 gaagacttgc ctgtggaaat gaaatcaagc gaggttgagt cttactacca gcttgtctct
    61981 aaaaggaagg gttcgctgat tttcaagcgt tgcttggact gggttttggc cttggtctta
    62041 ctggttctaa cttctcccat ctttctcatc ttgagcattt ggatcaagtt ggatagcaag
    62101 gggccagtga tttacaagca agagcgtgtg acccagtaca accgtcggtt caagatttgg
    62161 aagttccgta ccatggtgac ggatgcggat aaaaaaggaa gtctggtgac ttctgctaac
    62221 gatagccgta ttaccaaggt tggaaatttc atccgacgtg tccgtttgga cgaactgcct
    62281 cagttggtca atgtccttaa aggtgagatg tcctttgtcg gtacacgacc tgaagtgcca
    62341 cgttatacag agcagtatag ccctgaaatg atggcaacct tgctcttgca agcaggaatt
    62401 acctctccag ccagcatcaa ctacaaggat gaggacacca tcatcagtca aatgacggag
    62461 aaaggtctgt cagttgatca ggcctatgtg gagcatgttc ttcctgaaaa gatgcgctat
    62521 aacctcgcct atctccgaga gtttagtttc tttggggaca tcaaaatcat gtttcaaacc
    62581 gtgtttgagg tactaaaata aagtagtcat aagaaaatga gtacagataa aaggagcaaa
    62641 tcaatgccaa attacaatat tccattttca ccgcctgata tcacagaagc agaaattgct
    62701 gaagtagcgg ataccctgcg ttctggttgg atcacaacag gtcctaaaac aaaagaactg
    62761 gagcgccgct tgtctcttta cacacagaca cctaagactg tttgtctcaa ctctgcgaca
    62821 gccgctctgg agttgatttt acgcgttttg gaagtgggac ctggtgatga agtcatcgtt
    62881 ccagccatga cctatacggc ttcatgtagt gtcattacgc acgtgggagc aacccctgtc
    62941 atggtggata tccaagcaga tacgtttgag atggactatg acctgcttga gcaagctatc
    63001 actgagaaaa ctaaggtgat tatcccagta gagctcgcag ggattgtttg cgattatgac
    63061 cgtttgttcc aagtcgtgga gaaaaaacgt gacttcttta ccgcttcaag caagtggcaa
    63121 aaggccttta accgtattgt cattgtctct gatagtgccc acgctttggg atctacttat
    63181 aaaggacaac cttctggttc tatcgctgat tttacttcct tctcattcca tgctgttaag
    63241 aactttacaa cggcagaagg tggaagtgcg acttggaaag ccaatccagt gattgatgac
    63301 gaagagatgt acaaggaatt ccaaatcctt tcccttcacg ggcaaactaa ggatgctctt
    63361 gccaagatgc aactggggtc atgggaatac gatatcgtta caccagccta taagtgcaac
    63421 atgaccgata tcatggcttc acttggtttg gtacaattgg accgctatcc aagtttgttg
    63481 caacgccgta aggacattgt ggaccgctat gatagtggtt ttgcaggttc tcgcatccat
    63541 cctttggcac acaagactga aactgtcgaa tcttcacgcc acctctacat cacccgtgta
    63601 gaaggagcaa gcctagaaga acgcaacctc atcatccaag aattggctaa agcaggaatt
    63661 gcaagtaatg ttcactacaa accgcttcct ctcttgacag cctataagaa tcttggattt
    63721 gatatgacga actatcctaa ggcctatgcc ttctttgaga atgaaattac cctccctctt
    63781 catactaaat taagcgatga agaagtagac tatatcattg agactttcaa aacagtttct
    63841 gaaaaagtgc taactttatc aaaaaaatga caaactacag tcaagcgaaa gtgatcctgt
    63901 ccctaaaaag tctaattgag tgtaaaaact gttgttttca attgataata gtttacacct
    63961 gtagttgagg cctctttctc ctcagagaga gaatttttat aggattttcc tttcttgtgg
    64021 gagtcccgtg gtttgaaata agatgtgagc aatttggtat agcatttaga atccttacta
    64081 gacatcattt agaaaatcta gtgtcttgtt ctagttttca attcacccta ttttttgaaa
    64141 gacgtgagtt tccatgagtg agattgtgga aactagcgtc ttttttttgt tttcagaata
    64201 ttgttcaaag ttttgtgcct gtctttcatg ttctagtcat tcttttgcat gatagaattt
    64261 atagcatgtt gatattataa taacgcaaat atcccatatg tttagtgatg cttgctatac
    64321 atcattagat ctcctgcgag acaatctata aaacacttgt ctacgattac ctatatgccc
    64381 tattccagta ttttagaagc actgcatcta tttttatcga ggttaaatct agcttttata
    64441 gaaggtctat ttaagaaata tattgtagtg ttttagtttc aatccgccat atgagcgata
    64501 ttcaggtaaa tatccctggc gaatgcttgt atgacaaggt atttgttctt tcatttataa
    64561 tttacaacat atcaacaaat ttaaatatag taaatgggat attttatatt caagctaaga
    64621 aagatagcat cacttttgaa tggaaggcta aagagcaaac taggaagttg gccatagata
    64681 gctcaaaacc ctgctttgag gttgtagata tagtaaaatg aaacaagaat aggacaaatt
    64741 gatcgggaca gttaaatcga tttctaacaa tgttttagaa gtagaggtgt actattatag
    64801 tttcagtcta ctatagaact gaccaagtca gtaacctaga cttagggcaa ggcggcactg
    64861 acctagtttg aagagatttc cgaagagtat aaattttaat attttcttgt gttattcctt
    64921 gacaattcaa tttggaaaat atatgataaa gataatgaca gcggtgtcat tctatctatt
    64981 ttaagaaaag taataatcaa ttgttaaaaa tagtaaaaaa attggaggtt ctgatgaaat
    65041 attttgttcc taatgaggta ttcagtattc gtaaattaaa ggtggggact tgctcggtac
    65101 tattggcaat ttcaattttg ggaagccaag gtattttatc ggatgaagtt gttactagtt
    65161 cttcaccgat ggctacaaaa gagtcttcta atgcaattac taatgattta gataattcac
    65221 caactgttaa tcagaatcgt tctgctgaaa tgattgcctc taattcaacc actaatggtt
    65281 tagataattc gttaagtgtt aatagtatca gctctaatgg tactattcgt tccaattcac
    65341 aattagacaa cagaacagtt gaatctacag taacatctac taatgaaaat aagagttata
    65401 aggaagatgt tataagtgac agaattatca aaaaagaatt tgaagatact gctttaagtg
    65461 taaaagatta tggtgcggta ggtgatggga ttcatgatga tcgacaagca attcaagatg
    65521 caatagatgc tgcagctcaa gggctaggtg gaggaaatgt atattttcct gaaggaactt
    65581 atttagtaaa agaaattgtt tttttaaaaa gtcatacaca cttagaattg aatgagaaag
    65641 ctacaattct aaatggtata aatattaaga atcacccttc cattgttttt atgacaggtt
    65701 tatttacgga tgatggtgcg caagtagaat ggggcccaac agaagatatt agttattctg
    65761 gtggtacgat tgatatgaac ggtgctttga atgaagaagg aactaaagca aaaaatctac
    65821 cacttataaa ttcttcaggt gcatttgcta ttgggaattc aaataacgta actataaaaa
    65881 atgtaacatt caaggatagt tatcaagggc atgctattca aattgcaggt tcgaaaaatg
    65941 tattagttga taattctcgt tttcttgggc aagccttacc caaaacgatg aaggatgggc
    66001 aaatcataag taaggagagc attcagattg aaccattaac tagaaaaggt tttccttatg
    66061 ccttgaatga tgatgggaaa aaatctgaaa atgtgactat tcaaaattcc tattttggca
    66121 aaagtgataa atctggggaa ttagtaacag caattggcac acactatcaa acattgtcga
    66181 cacagaaccc ctctaatatt aaaattttaa ataatcattt tgataacatg atgtatgcag
    66241 gtgtacgttt tacaggattc actgatgtat taatcaaagg aaatcgcttt gataagaaag
    66301 ttaaaggaga gagtgtacat tatcgagaaa gcggagcagc tttagtaaat gcttatagct
    66361 ataaaaacac taaagaccta ttagatttaa ataaacaggt ggttatcgcc gaaaatatat
    66421 ttaatattgc cgatcctaaa acaaaagcga tacgagttgc aaaagatagt gcagaatatt
    66481 taggaaaagt atcagatatt actgtaacaa aaaatgtaat taataataat tctaaggaaa
    66541 cagaacaacc aaatattgaa ttattacgag ttagtgataa tttagtagtg tcagagaata
    66601 gtatattcgg tggtaaagaa ggaattgtta ttgaggattc aaagggtaaa ataaccgttt
    66661 taaataacca attttataat ttatccggta agtatatatc attcatcaaa tctaatgcaa
    66721 acgggaaaga acctgttata cgtgatagcg atggtaattt caatattgta acggagaatg
    66781 ggctttacaa aattgtaaca aataatttaa gtgataaaaa cgaaaaagaa aaaaacaaag
    66841 aggaaaaaca atctaattca aataatgtaa ttgatagtaa ccagaagaac ggagagttta
    66901 actcaagtaa agataataga caaatgaatg acaagatcga caataaacaa gataataaga
    66961 cagaagaagt aaactataaa atagttggag atggcagaga aactgaaaat catattaata
    67021 aatctaaaga aatagtagat gtaaaacaaa aattaccaaa gactggttcg aacaagatta
    67081 tggaactatt cttaacagtg acaggaattg gtttactttt gacactaaaa gggttgaagt
    67141 attatggtaa agataaataa aatttgttcg atacaaggaa gttccgtaga aaatgaggat
    67201 attgtaggtt cacaaaatca gtatttttgg attattggtg gagctacaga tttatataat
    67261 tctaaagagg agataggtta ttcagtctca gaagttgtac atattttatc agaaagtttg
    67321 tcggttaatt gtaaagaatc aaaaactctt aaacaaatat ttgaaactgc tttactcgag
    67381 gttaaagatg aaatcggttt aaactcatat gaattaacag agtataataa aatgaaataa
    67441 taataggaca aatcaatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag
    67501 gtgtactatt ctagtttcaa tatactatat tatcgcttac caacatttgc ttttatattt
    67561 gctaaacttt cagaaaaaaa gttggagtat atgatgctag gtgactgcgt catgttagta
    67621 aacgaaatgg aaataacgga tcatagagta gataacttat ttgaaaaagg gaaaaatgag
    67681 ataaaagatc caattggtac aaatagtgtt ttaaataaaa aaattatttt acaaaaaatc
    67741 agaaaattat ctaatcaacc gagtgggtac tggataggtt cgttggatga gagattttta
    67801 gaccatgcta ttattaatca aatagatgtt actagtgaac aaattgtttt aatgagcgat
    67861 ggcttttatg aattctatca aaataatcaa aataaaactt ttgaagagtt aattaagatg
    67921 agatttaatt cttctgctat tgatccaatc tatggaaaga aagatgatgc aagtattgta
    67981 gttattgatg tttgatatat tgtttaaaat attaattgtt actattgaac tttgttaaga
    68041 agaggtacct aaatgttaag gttatattta gaaaatgaaa ttatagaatt atcaaataat
    68101 ttagagacca tttgggtatc tgtgcttgat aaatatgaga agttatttga atatttatca
    68161 aatgaagaac gaatagaatt gattaaagaa gatttaatca taaatgagtc agttctaaat
    68221 gttgataaaa aaggatatga gttaatttgt ttacaacatc ccgtttcata tgacttaaga
    68281 agaattatta gtgtaataaa aatatcaact gacattgaac gtattgggga tagaattgtt
    68341 gaaattttaa aaaatctaca gattattcaa aataatgaaa ttttgaagaa aattatttca
    68401 gaaataaaaa tacttcatga agttatcgga ctgcatatga atagggctat atcttgttat
    68461 agagaggaac aatctggatg tttagatatg gttgttatac aaaaacagaa tgagatagaa
    68521 gagcttagta caaatattga aaagaaaata atgaattaca tatttgaaga tgatgggaat
    68581 gtttctgaag taattggtgc tttagatatt attcatcacc ttgataaaat tgctcatact
    68641 acgcaatcaa tttataaatg gataatgtat agaaaatatg ggaacataaa ttagaaagaa
    68701 aaatatatga aaacaattat tgataatttt gttgatagag taattgaata cggaatgtat
    68761 aatgaaattg acaaaatata tgtgaaaaat agagtactag cgttaatagg tgaggaggga
    68821 actgatcgca tttccgatga aaatgacctg aaacaaataa aagattactt agtggaaatc
    68881 gccttaaaaa acggtaaaat taaagattta atcgaggaaa aggaatgttt aggagcagag
    68941 ttaatgaatt tcatagttcc tttacctagt cgattaaatg atattttttg gagttcatat
    69001 gatatatcac ctcaagaagc agttgaagag ttttataagt taagtaaaga tagtgattat
    69061 attaaaactt ctgctattgc taagaatatt gagtttcgag catcaactaa atacggagag
    69121 ctagagatta cgataaattt gtcaaaaccc gaaaaagatc caaaaacaat tgctgctgaa
    69181 aaattagtaa aagccactaa ttatcccaaa tgtttactat gtatggaaaa tgaaggatat
    69241 caggggcgaa taaattatcc agcacgttcg aatcatagaa ttattcgatt gaaatttggt
    69301 gacgaagtat ggggattcca atattctccc tacttatact ttaatgagca tgcgatattt
    69361 ttaaatagtc aacatgtacc aatggctatt acctctaaaa catttgaaca attattggag
    69421 attgttgata ttttgccagg atattttgct ggttcaaatt ctgatcttcc tatctcagga
    69481 ggctccattc ttagtcataa ccactaccag ggagggaaac atattttccc aatggaaaaa
    69541 gcaaaatttg agagtgaatt tcgttttaaa gactttgagg atgttaatgc tggtattgta
    69601 aaatggccaa tgtcagtaat taggttacaa agtgaaaata aaaatcgctt gttagattta
    69661 gctactaaaa ttctaaataa gtggagagaa tattcagatt tagaagtaga catcattgct
    69721 atgactgaag atgtcccaca ccatacggtg actcctattg ctcgtaaagt ggacgggaga
    69781 tatgaattag atattgttct aagagataat catactactg aacagtaccc agatggtgtt
    69841 ttccatcctc atcaagatgt acaacatatt aaaaaggaaa atatcgggtt aatcgaagtg
    69901 atgggacttg cgatattacc acctcgtttg aaaccagagt tagaagaagt tggaaaatat
    69961 cttttaggag aggataacgc aattgcggat tatcatttag aatgggccga ccaattgaaa
    70021 gaaaaatatc ctcgcattaa taaagaagag gttaatagcg tagttcaaca cgaagcagga
    70081 caagtgtttg cgagagttct ggaagatgca ggagtttata agaatacacc gtctgggcat
    70141 gaagcgttta tgagatttgt taagtcggtt ggaattaatt aggaggaaac aaaaatggca
    70201 atattggtaa caggcggagc tggttatatt ggtagccata ccgtagtaga attactaaat
    70261 ttaggaaagg aagtcatcat tgtcgacaac ctttcgaact ctagcatctt ggtgctagac
    70321 cgtattgaag caattacagg aatacgtccc gtgttttacg aattagatgt ttgtgataaa
    70381 ccagcattga gaaaggtatt tgaacaagaa tcgattgatg ctgcaattca ttttgcaggt
    70441 tataaagctg tcggagaatc cgtgcaaaag cctgtgatgt actacaaaaa taatattatg
    70501 agtacattgg cacttgttga agtgatgtca gaatttaatg ttaaaaagat tgtcttttct
    70561 tcaagtgcga ctgtatatgg aattaacaat cagtcacctc taattgagac gatgcaaaca
    70621 agtgcgacaa atccttatgg gtatacgaaa gtgatgcttg agcaaatttt aaaagatgtt
    70681 catgtggcag attcagaatg gagtattgcg ttgcttcgtt atttcaatcc aattggtgct
    70741 catgagtctg gtttgattgg ggaagatccc tcaggacttc ctaacaactt gatgccttat
    70801 attgcacaag tagcggtagg taagctatca gagctaagtg tgttcggaaa tgattatgat
    70861 acgcttgatg gtactggtgt gcgtgattat atccatgtag tagatttagc aataggacat
    70921 ataaaagctt tagaaaaagt atctgaaaaa acagatgttt atatctataa cctaggctcg
    70981 ggagaaggca ctagtgtatt acaacttgta aatacatttg aaagtgttaa taagatccct
    71041 attccttata aaatagttcc aagacgttca ggagacgttg caacttgtta tgcaaatgca
    71101 gacaaagcat ataaggaatt aaattggagg acaacaaaat cgattgaaga catgtgtaga
    71161 gatacatgga attagcaatc aaaaaatccc aatggctata attgatgata ctgtctatat
    71221 gagtgctgta ttttggaaaa attacttaac cttttaatga aatgcatatt taatgaaaga
    71281 taaattaaaa aaaatgtttg acagcgcttg acaaaggaaa cggtttcatt gtataatgta
    71341 aacatagtga caccgatgtc aaatataaaa aagaaggtct ttatatgaaa aacttaacaa
    71401 aaattaagtt caaagaaaat ggggaattta atcatttccc tgggaataca gttgtagcaa
    71461 atctttatac taaacaagat ttgatggaag ttgttgatat tattcaatca cgttatagag
    71521 aattaccatt tatcgataag tttactttaa ctccaaggaa ttctattcac atgactgtaa
    71581 ttgaattgtt gtgccatgaa aatcgtgaaa cggagttttg gagcagtaat cttcctctag
    71641 atacaccttt acaggaaata catgattact ttgctaaaca acttgaaatt tttccattgt
    71701 tggatgaaga aattcatatg cgtataactg aaatgggaaa acaaaacata ctagttgaac
    71761 ctgcagatga agcttctgca aagagattag aagaaattcg tacttatgtc tcagaaaaag
    71821 caggtgtttg tttccctaat catgatagat atcaattcca tatttcaatt gggtatcttc
    71881 ggattcctct aaccgaagag gaggaagaag agtttactaa agtcagagca gaattaactg
    71941 aaattttatt agagaagatt ccaactatta ctgtaaaccg tattgactat actgtatttg
    72001 aagatatgag acaatttgtt ccatatcacg aaaaatttaa ataaaataat aaaaaaggag
    72061 aacttatcat gaaaaaaatg aaagtttggt ctactgtact tgcaacggga gttgctctta
    72121 ctacacttgc tgcttgctct ggaggttcaa attctacgac tgcttcttca tctgaagaaa
    72181 aagctgataa aagtcaagaa ttagttatct attcgaactc agtctcaaat ggtcgtggtg
    72241 attggttaac tgctaaagca aaagaagctg gttttaatat aaaaatggtt gatatcgctg
    72301 gcgctcaatt agcagaccgt gttattgctg agaagaataa tgcagttgca gatatggtat
    72361 ttggaattgg tgctgttgac tcaaataaaa ttagagatca aaaattacta gtacagtaca
    72421 agcctaaatg gttagataaa attgatcaat ctttatcaga taaagataat tattataatc
    72481 ctgtgattgt tcaaccatta gttttaattg gggcgcctga tgtaaaagaa atgcctaaag
    72541 actggacaga gttagctagt aagtataaag gtaaatattc aatttatggt cttcaaggtg
    72601 gtacaggacg ggcaattcta gcaagtatct tagttcgtta ccttgatgaa aaaggagatt
    72661 taggcgtatc agaaaaagga tggggagttg caaaagaata ctttgcaaat gcctatactc
    72721 ttcaaaaagg tgaaagctca gttgttaaag cgttagataa agaaagccca attcaatacg
    72781 gtatgatctg gggttctgga gcgttaatcg gacaaaaaga acaaaatgtt gaattcaaag
    72841 ttatgactcc tgagattggt gtaccatttg taactgaaca aactatggtt ttaagcacta
    72901 gtaaaaaaca agcgttagct aaagaattta ttgattggtt tggtcaatca gaaattcaag
    72961 tagaatatag taaaaaattt ggatctattc ctgcaaataa agatgcccta aaagagttac
    73021 ctgaagatac gaaaaaattt gttgatcaag tgaaaccaca aaatattgac tgggaagctg
    73081 ttggaaagca tttggatgaa tgggtagaaa aagctgaatt agaatacgta aaataagaaa
    73141 taagagttat tttttatgtc caagtctctc tattatttct aaatttaagg aagaaataaa
    73201 gagaggcttt tggtttagta atagagggag ttagtgagat gattaaattt gataatattc
    73261 aaattaaata tggtgatttt gttgcaattg ataatctgaa tttagatata catgaagggg
    73321 aattctttac atttcttggg ccttcaggat gtggtaaatc aactactttg agagcattgg
    73381 taggtttttt agatccatca tcaggaagta ttgaagttaa tggaacagat gtcactcatt
    73441 tggaacctga aaagcgtgga attggtattg tatttcaatc ttatgcgcta tttccaacta
    73501 tgactgtttt tgataatatt gcatttggtt taaaagttaa gaaggtagct ccagatgtta
    73561 ttaaagctaa agtatcagca gtggcagcaa aaattaagat ctctgatcaa cagttacagc
    73621 gtaatgtatc agaattatct gggggtcaac aacaaagggt agcattggct cgtgctctgg
    73681 ttcttgaacc taaaattctt tgtctagatg aaccattgtc aaaccttgac gcaaaattac
    73741 gtgtagattt gagaaaagag ttgaaaagac ttcaaaaaga gttaggtatt actactttat
    73801 atgttactca tgatcaagag gaagccttga ctttatctga tagaattgca gtctttaaca
    73861 atggatacat cgaacaggtc ggtacaccag tagagattta tcataattct caaactgaat
    73921 ttgtatgtga ttttattgga gatattaatg ttttgaccga tgaaacagtc cacgaagtat
    73981 tactgaaaaa tacaagcgtt ttcttagagg ataaaaaagg ttacattcga ttagagaaag
    74041 ttcgattcaa tcgtgaaact gaacaagatt ttattctaaa agggacaatt attgatgttg
    74101 agttttctgg agttacaatt cactatacaa taaaagtttc tgaaagtcag attcttaatg
    74161 taacaagtat tgatagtcag gctgctatta gatctgtcgg agaaagtgtg gaattattta
    74221 tcacaccatc agacgttctg caattttaag gaggtgcagt atgcgtcata aattaaattt
    74281 aaaagattgg cttattcgtt tagggttaat ctggttctta gtaacattta ttatttatcc
    74341 aaactttgat ctagtagtga atgtatttgt aaaaggagga gaattttccc ttgatgctgt
    74401 acatcgtgtt ctaaaatctc agagggcact tcagagtatt atgaacagtt ttaagttagc
    74461 attttcactc attattacag ttaatgtcgt aggtattctt tgtgttctat ttacagagta
    74521 ctttgatatt aaaggtgcta aaattttaaa attaggttat atgacctctt taatttatgg
    74581 aggagtggtt ttagcgactg gatataaatt tgtctatggt ccttatggat tgattacaaa
    74641 atttttacaa aatgttatcc cttctttaga ctctaactgg tttattgggt atggtgcagt
    74701 cttattcatt atgacatttt caggaactgc taatcataca ttgtttttaa caaatacaat
    74761 tcgaagcgtt gactatcaca ctattgaggc tgctcgaaat atgggagcaa aaccatttac
    74821 tgttttccga aaagtagtgt taccaacctt aattccaact ctatttgcac ttactattat
    74881 ggtttttctt agtggtttat ctgcagtagc agcacccatg attgttggtg gtaaagaatt
    74941 tcaaactata aatccaatga ttattacatt tgcagggatg gggaattctc gtgatttagc
    75001 tgccttactt gcaattattt taggtattgc aactacaatt ttgcttacta tcatgaataa
    75061 gatagaaaaa ggtggaaatt atatttctat ctctaagact aaagcgcctc ttaaaaaaca
    75121 aaaaattgcg tctaagcctt ggaatatcat tgctcacatt gtagcatatg gattgttcac
    75181 agttttcatg cttccactaa tttttatagt attatactca tttacagatc cagttgcaat
    75241 tcaaacaggt aacttaacat tatcaaactt tactttagaa aattatcgct tattctttag
    75301 taatagtgcg gcattctctc cattcttggt cagctttatt tattctatta ttgctgcgac
    75361 aacagcaaca attctcgcag ttgtatttgc tcgtgttgtc agaaaacata aatctcgttt
    75421 tgatttctta tttgaatatg gtgctctact tccttggtta ctaccaagta cacttttagc
    75481 agtaagttta ttatttactt ttaatcagcc acaatttctt gtcttgaatc agattttggt
    75541 aggtagtttg gtaattctac ttattgcata tatagttgta aaaatcccat tttcttatag
    75601 aatggtacgt gctattttat ttagtgttga tgatgagatg gaagatgcag caagaagtat
    75661 gggtgcttca cctttttata ctatgatgaa ggttatcatt ccatttattt taccggttgt
    75721 tctctctgtt attgctttaa actttaactc tttattaact gacttcgact tatctgtatt
    75781 cctttaccat cccctagctc aaccattagg tattacgatt cgatctgcag gtgatgaaac
    75841 agcaacatct aatgcacaag ctctggtatt tgtttataca attgttctga tgatcatttc
    75901 tggaacggta ttatacttca cacaaagacc ggggcgtaaa gtaaggaaat aatcatgaca
    75961 gccactagtc ttgggttatc aaatattgaa atagttgtca ggattgtttt atcagtagtc
    76021 attggtagta taattggttt agagagaggg agcaaatccc agcctgcagg catccgaact
    76081 tatagtattg tttgtctagc tgcatgtttg attatgatga cgaatgaata cgtatcttat
    76141 aaatttggga caggagatcc tacacgatta ggagctcaag ttatatcagg tgtgggtttt
    76201 ctaggcgctg gaacgattct tattacagat aaaaagaaaa ttacaggtct gacaactgca
    76261 gcaggcattt gggcttcggc aggaattgga ttagctattg gagtaggttt ttatgaggga
    76321 gctcttttag tagccatttc tgtttggggt gtgatatcca tgttccaacc actaaaaaaa
    76381 tatctgcaaa atcgttctaa aatgattgaa ttgtatatag tggttaaatc tacagaagcc
    76441 tataatcgtg tattggttta ttgtgcagaa aatggtatca gaatgaccga ttcaagaaca
    76501 gcgtttggag atgttaattc tgacagaatt gaatactttg atgttccgga caaaaaaata
    76561 gcgtcattta ttactctgga attatcaggt agatttgaac atcttcgact gatggaagaa
    76621 attgctaata ttgtaggtgt tatttatgtc gaagaaatta gctgaaattt agtaaacaaa
    76681 gggacagatg tttttgtcct tttgtttttt agatgtttta atcatctaat ttttgagtag
    76741 atttttgctc agaggttttt atgaaagatt ataaaatcaa ttttgattta ggtaaaatag
    76801 aatattttga taataattgt ttgatacaag tatacaaatt tatttctttt tatgatattt
    76861 gtgaaatggt gtttgccttt catttacctc ctgatgagtt gataacaaat gttatcttta
    76921 aagaaaaaat taactctatg ttaaaatgtt acattgacag gctattatat gtttttataa
    76981 atcctacaca ttttactgaa aaagttaatc tacaatttta tggtagtttt ttctcatatg
    77041 aatttatttg tcgtgaagtt ggaaacattc ttaaaaataa aggtgtgaaa tgcaatttaa
    77101 acttttttga aggggaagaa tatttgtaaa attaattttg tgaatttgtg gatcttaaat
    77161 aatttactaa attctcttgt taaaaaaaat taaatattgt atagtaatat tagaatgttc
    77221 gtaatggagg actgaaatga aaaatataaa tgggaaaaag gtaactattt atgatattgc
    77281 acgtttatca ggtttttctc caaaaacagt ttcacgagtt attaatggtg gagtaaatgt
    77341 taaagaagaa acttatcaag cgattcaaaa agttatagag gaattgtcgt atattccaaa
    77401 tgcgtatgca aaaaatttaa ctaaaaaaga agctataaat atattgattt ctgtaaaaaa
    77461 aatcgactct tttcctttaa tttggtttca tacgctgtta gataaagtgt tacggacgtg
    77521 taaagaattt ggtgttaatg ctatagttga gtactttgga gaggaggata caattagtaa
    77581 ttcaattata tcaagcacag gtagcctagt agatggtgtt attgtttttt atgaaagtgt
    77641 agatgatatc agaattcagt atttaaagaa gaaccatatg ccttttcttg ttttcggtga
    77701 atctcaaacg tctggagtag tctatgtatc taataataat tttcaagcta cttatgatat
    77761 gatgaaagct gtaactgaag aaaaatttaa aaatatgtgg ttgcttatgg gaggagaatc
    77821 ccatgttaat aaggatcgtg aaagaggtgt gcgttctttt ctgaatgata aaaattactt
    77881 tatggattta aaagtcattt atggcttatc tacaattgat tcagtttatt cttatgcaat
    77941 gcagcacttg actacccaaa attatccgga cattattttt gtttcaggag atgaaaaggt
    78001 tcagggcttg attcgtgcgt gctatgagaa aggaattctt attccagatg atatttctat
    78061 cattggattt gataatattc ctatttctca gtattatact ccagctttgt ctacaattgc
    78121 tcccaattat gttaaattgg ctaaagaaat gatagaaggt gttttagcaa ttattaaagg
    78181 ggaaagtgtc acatctgttg aagtttctcc taaatttgtt aggagacaga gtttctagta
    78241 ttgtttaatt cttgaaaatc ctagtggaaa agatggagtg ttctaaaata agttctgttt
    78301 agcctccatt cagtttctat tgagttggat ccaatttcta acaagtggga catgttcatg
    78361 ttcgatctaa ggaagacatg gtcacattcg aatgatattt tcaaaaaaat cgtaaaaaag
    78421 tcttgacaaa gaaaaaacaa agtattaaaa taagttcaac aaatcagaaa agtaactatt
    78481 tttgatcttc agggagcctg tggtggttgt gaataggtgg ttggaagtag tgaaagtggg
    78541 ctgattttga aaatgaattt gaaacaatga aaattcggtg cgcacacctt acagtgcagc
    78601 ttgttgttaa acaaggcaga gatgtaaagg gatagtccct ttataattga ggtggcaccg
    78661 cgttaccaac gccctcacac ggaagtatat tttgtgtgtg ggcttttttc tatccgtcgt
    78721 ttggtttatc ttttattagg gccttaagtc gctttgatga acttgagttc tatctacagc
    78781 tccttgccta ctactaaaag caaacaaaaa gctggactaa tacgaaaaaa gctagtaata
    78841 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa aacactgttt
    78901 tgaggttgtg gatagaactg acgaagtcag ctcaaaatac tgttttgagg ttgtggatag
    78961 aactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg acgaagtcag
    79021 taaccatacc tacggcaagg cgacgttgac gcggtttgaa gagattttcg aagagtataa
    79081 aggtgtatcg aaataaaaat ctcctcatca atatctctgg tcgtggaggc aaggacctag
    79141 ctgcgattgc agattaccta gaagctaaaa aataatagat ggaaaaatta cagtcttttc
    79201 tctcacagag agcttgtggt tgctgaaaac aagcagagaa agctgtaaag ttgggttcat
    79261 ctgaaacgag agaagaaaac atcattctca agggagtgcc ctttatcgca cagcctgtta
    79321 caggaggtat ctgagacagg aatgagagat aggagaaatc ctataattga ggtggcaccg
    79381 cgaatttcgt cctcacgcaa gttattttgc gtggggattt ttcatacagt caccacggac
    79441 tagaagtaga actgaaaggg aaattacaat ggaacgaatc attcatggag atgtcttatc
    79501 accaatcttg gcttatatgc gcttaaaggg gcaacacaag gttatcttag agagtattcc
    79561 gagagacaag gaaacagctc gtttttctat cttagcctat aatcctgttt ttgagattaa
    79621 gtttgaaaat ggagttcttt atcaaaatgg tcaagtgatt gatcgagatc ccttggattt
    79681 cctttatgaa gtgattcata agagtcagca ccactcagag ctaccttttg gtggtggagc
    79741 cattggtttt gtgggttacg atatgatttc gctttatgaa gaaattggtc aaatccctga
    79801 ggatacaatt gggacgccag acatgcattt ctttgtctat gagagctata tggtctttga
    79861 ccacaagaag gagaagatac atgtcataga ggatgctctc tatagtgagc gcagtcaaga
    79921 ggccttggaa aaatccttga accaagtgct tgaggaatta cgcattcctg ctccaaatga
    79981 atttgaagac ttggatttat caccacttga cttcaaaccg catatcgctc cacataagtt
    80041 tgaggtaatg gtagaaacag ctcgtgactt gattcgtaat ggtgatatgt tccaatgtgt
    80101 actcagccag cgtttctcag cagaagttac tggaaattca tttgacttct acagaaatct
    80161 ccgcgtgacc aatccatcca attacctcta tttctatgat tttggggatt atcaaatcat
    80221 cggagctagt ccagaaagtt tagtttctgt caaaaatggc atcgtgacaa ccaatccgat
    80281 tgcagggacg cgaccaagag gggttacgga tgaagaagac aagaccttgg cgactgacct
    80341 cctctctgat gagaaggaaa cagcagaaca tcgaatgttg gtagacttgg ggcgtaacga
    80401 tattggccgc atctctgaaa cggccagtgt ccaagttact aagtatatga aggtggagct
    80461 cttccgctac gtcatgcatt tgaccagcgt ggtcaagggg cgtttgcttg cagaactcac
    80521 tgccatggat gccttgaaag caacgcttcc tgctggaacc gtttctggag caccaaagat
    80581 tcgggcgatg agacgcatct atgaactgga aacggaaaaa cggggcgtat atgcaggagc
    80641 aatcggctac ttgtctgcga cgggtgatat ggatttggcc attgccatcc gaaccatgat
    80701 tctcaaaaat caaagagcct atgtgcaggc tggggcaggg attgtctacg actctatcgc
    80761 ccaaaacgaa taccaagaaa ccattaacaa agcaaaatct atgactagaa ttggagaact
    80821 aagaccatga ttttattgat tgacaactat gattctttta cctataactt ggcccaatac
    80881 attgggaatt ttgcagaagt tcaggttctg agaaatgatg attccaagct gtatgaagaa
    80941 gctgaaaaag cagatggtct ggtcttttct cctggtcctg gttggccagt tgatgctgga
    81001 aagatggaag acatgattcg tgattttgca ggcaagaagc cgattctagg gatttgtttg
    81061 ggccaccaag ccattgcaga agtctttggt ggtaagctag gtttggctcc aaaagtcatg
    81121 catgggaaac agagcaatat caactttgaa gcgccatctg ttttgtatca aggtattgag
    81181 gatggacgtg cggtcatgcg ttatcacagt attttgattg aggaaatgcc agaagacttt
    81241 gaagtgacag ctcgttcgac tgatgaccaa gccatcatgg ggattcaaca taaaaaccta
    81301 ccgatttatg gcttccagta ccatccagag agcattggaa cgccagacgg cttgtcttct
    81361 attcggaatt ttatcgagaa ggttgtaaag tgaggaaact aggatgaaag agattattga
    81421 aaaactagca aaatttgaaa atttatcagg tgtggaaatg acggatgtca ttgagcgtat
    81481 cgtaactggg cgtgtaactg aagcgcagat tgcttctctc ctcttagctc ttaagatgaa
    81541 gggggaaaca cctgaagaac gcacagccat tgcccaagtc atgagaggac atgcccagca
    81601 tattccaact gagattcatg atgccatgga caactgtggt acaggtgggg acaagtcttt
    81661 cagttttaat atttccacaa ctgcagcctt tgtcttggct ggtggcggta ttcacatggc
    81721 caagcatggt aaccgctcga tttcttctaa atctggttcc gcagatgtcc tcgaagcctt
    81781 gggaatcaat cttgacctca aaccagctga actaggtaag gtctttgata aaactggaat
    81841 cgtctttctc ttcgctaaaa atatgcaccc agctatgaaa tacatcatgc cagctcgttt
    81901 ggaattggga attccaacga ttatgaactt gactggtcca ctgattcatc caatggcttt
    81961 agaaacacag cttcttggaa ttagtcgtcc agaactccta gaaagtacag ctcaggtttt
    82021 gaaaaatatg ggtcgcaaac gtgccatcgt ggttgctgga ccagaagggt tggatgaagc
    82081 tggcttgaac ggaacaacca agattgcact tcttgaaaat ggcgaaatca gcttgtcaag
    82141 ctttactcca gaggatttgg gaatggaagg ctatgctatg gaagatgttc gtggtgggaa
    82201 tgctcaggaa aatgcagaaa ttttgcttag cgttctgaaa aacgaagcaa gtccattctt
    82261 ggaaacgaca gtcttgaatg ctggtcttgg tttctatgct aatggtaaga ttgatagcat
    82321 caaggaagga gttgccttgg cccgtcaagt gattgctaga ggcaaggccc ttgaaaaact
    82381 cagactgtta caggagtatc aaaaatgagt caggaatttt tagcacgaat cttagagcag
    82441 aaggcgcgtg aggtggagca aatgaagctg gagcaaatcc agcctctgcg ccagacctat
    82501 cgcttggcag aatttttgaa gaatcatcag gaccgcttgc aggtaatcgc tgaggtcaag
    82561 aaagctagcc ctagtttggg agatatcaat ctcgatgtgg atattgtgca acaggcccag
    82621 acttatgaag aaaacggagc agtgatgatt tcggtgttga cagatgaggt tttctttaaa
    82681 gggcatttga attatctacg ggaaatttcc agtcaggtag agattccgac gctcaacaaa
    82741 gactttatca tagatgaaaa gcaaatcatc cgcgctcgca atgcaggtgc gacagttatc
    82801 ttgcttattg tggcagcctt gtccgaagaa cgcctcaagg aactgtatga ctacgcgaca
    82861 gagcttggtc tggaagtctt agtggagact cacaatctag ctgaactaga ggtagcccac
    82921 agacttggtg ctgagattat cggggtcaac aaccgcaact tgactacctt tgaggtcgac
    82981 ttgcagacca gtgtagattt agccccttac tttgaggaag gtcgctatta catttctgaa
    83041 tctgccattt tcacagggca ggatgcggaa cgactagccc catactttaa cggaattttg
    83101 gtagggacag ctcttatgca ggcagaaaat gtggcccaga gaatcaagga gttgcagatt
    83161 gacaaaggtt aaaatttgtg gactatcgac caaagaagcg gtggaaacag ccgtttcagc
    83221 aggagccgac tatatcggtt ttgtctttgc acctagtaaa agacaggtga ctttagaaga
    83281 ggcagctgag ttggcaaagc ttattcctgc agatgtgaaa aaggttggag tatttgtttc
    83341 accaagtcgg gtagaactgc tggaagcgat tgacaaagtt ggcttggact tggttcaagt
    83401 tcacggtcag gtggcagctg atttatttga gaatttgcct tgtgccagta ttcaggctgt
    83461 gcaggtagat ggaaatgggc atgtccccaa ttctcaggca gattatctac tctttgatgc
    83521 ccctgtggca ggaagtggtc agtcctttga ttggggtcaa ctggatacga ctggactagc
    83581 acagcccttc tttatcgcag gtggccttaa tgaagataat gtagtaaaag caattcaaca
    83641 ttttactccc tatgcagtag atgtatcgag cggagtggag acagatggac aaaaagatca
    83701 tgaaaagatt agaagattta tagagagggt aaagcatggc atatcaggaa ccaaataaag
    83761 atggatttta cggaaaattc ggcggacgtt ttgtcccaga aacattgatg acagcagttt
    83821 tggagttgga gaaggcctac cgtgaaagtc aggcagaccc aagtttccaa gaggaattaa
    83881 accagctttt gcgccagtac gtaggacgtg aaactcctct ttattacgca aaaaacttga
    83941 cccagcatat cggcggagcc aagatttatc tcaaacggga agaccttaac catacaggag
    84001 cccacaagat taacaatgcc ttgggacaag tttggcttgc caaacgcatg ggtaaaaaga
    84061 aaattatcgc agaaactggt gctggtcagc acggtgtggc aactgcaact gctgcggccc
    84121 tctttaacat ggaatgtacc atctacatgg gtgaggaaga tgtcaaacgc caagccctca
    84181 atgtcttccg tatggagctt ttgggagcta aggtcgaggc cgtgacagat ggttcgcgcg
    84241 tgctcaagga tgcggtcaat gcagcccttc gttcatgggt ggctaatata gatgataccc
    84301 actatatcct tggttctgcc ttggggcctc atccatttcc agaaattgtt cgtgacttcc
    84361 aaagtgtcat tggtcgagag gctaaacaac agtaccgtga cttgacagga caaaatctgc
    84421 cagatgccct agtagcctgt gttggtggtg ggtcgaatgc catcggtctc ttccatccct
    84481 ttgtagaaga tgagtcagta gccatgtatg gagctgaagc ggctggattt ggtgtggata
    84541 cggagcacca cgcagctacc ttgaccaagg gtcgtccagg tgtccttcac ggttccctca
    84601 tggatgtgct ccaagatgcc catggtcaaa ttcttgaagc cttctctatc tcagcaggtt
    84661 tggactatcc tggtatcggt ccagagcatt ctcactacca cgatattaaa cgtgccagct
    84721 atgtccctgt gacagacgaa gaagccttgg aaggattcca actcttgtct cgtgtggaag
    84781 ggattatccc agctttggaa tctagccatg ctatcgcctt tgcggtgaaa ttggccaaag
    84841 aacttggacc agaaaagtct atgattgtat gcctatcagg tcgtggggac aaggatgtgg
    84901 ttcaagtaaa agaccgcttg gaagcagatg cagcaaagaa gggagaagct catgcctaag
    84961 acactaacaa aaaaattaaa tgctattaaa gcagctggaa aaggaatttt tgttccctat
    85021 atcatggctg gtgaccacga aaaaggtttg gatggtcttg ctgaaacaat tcacttttta
    85081 gaagatttgg gtgtctctgc aattgaagtg ggtattccct tttcagaccc tgttgcagat
    85141 ggacctgtta tcgaagaagc tggcttgcgc agtttagccc acgggacctc tacccaggct
    85201 ttagttgaaa ccttgaaaac cattgaaaca gagattccac tggtcatcat gacctacttc
    85261 aaccccctct ttcagtacgg tgtggagaac tttgtcaaag atctggctga tacagctgtg
    85321 aagggcttga ttatcccaga cctgcctcat gaacatgcca actttgtaga accatttttg
    85381 gcagatacag atatcgcctt gattccttta gtaagcttga ccacaggaat tgagcgccag
    85441 aaagagttga ttgaaggggc ggagggattc gtctatgccg ttgccatcaa tggggtaaca
    85501 gggaaatcag gcaattaccg tgcagatttg gacaagcact tggcgcaact tcatcaagtg
    85561 gccgacatcc cagtcttgac aggttttggt gtatctagtc aagccgatct ggaacgcttc
    85621 aatgcggtgt cagatggtgt tatcgtcggt tcgaaaatag taaaagctct ccaccaagga
    85681 gagccgattc aggactttat caaacaagca gtagcttacc aaaaataatt aaacaagtag
    85741 caagtaagag gaaaggcacg aaaggaagtc tttccttttt cttttgcagg agaaaggcta
    85801 gttttatagt gaattgaatc tggaatatta cactacggtt cctaaaatat tttaagaaag
    85861 tgatttgaat ttcccaataa atttgttcag tttttaattg attttactat agaagatata
    85921 attttctaaa ttactctgac acagaacttt aagaaaaagc taattattgt agtaatttct
    85981 ttaagaaaat gatataattc attaaaaagt atttggagga ggaagaatta tgttgaatca
    86041 ggatctcttt gattcgcttg aggcacaaaa aattgtagat actttgatga aagggcaaaa
    86101 agattatgta gatgaacgtc tagaaaaaag agagacaatg atagtgtcga atggttatgc
    86161 atggacgcga cctaatcata ttgatactgc atttgcatca gcagatttgt ttgagtataa
    86221 attacaatta gcaggacaga cttggggata tttagaattt gaaacaaata cagaaaaata
    86281 tgggaaagta ttgttaatta taaagggtaa gaagcgactt acgaaccaat ttcctttggt
    86341 acaaaaaaat aagagtggct acttatttga atatgctcaa atgaatacac tttatcttaa
    86401 tcaacattct tcctacaaaa atgatgaaga tagtcattcc tttccaattc agatggagtt
    86461 agtttctgat gaaatgattc aagaaattga acaagctacc aaaaattcga atatcgaaaa
    86521 atttatgatt ttaacttatg aggcggactc agaaaacaat attatatctg tagatgttgt
    86581 tatgcctgat gcacgaactg gtcagttaca cttgattcaa gatttgtctg agtatattca
    86641 atcaagttcg taccatttcg aagaagctaa ataccaagat attcctaatt tttcagaatt
    86701 atcggaaaca gaagattttg aaattattcc aagaatagaa aaacaagaag gtcaaaagta
    86761 gtaaggagta tgtaaatgtt taatggtcgg gtattgaaag aattacggct gttaaatggt
    86821 ttaagtagag cagaattagc tcagagaatt aatttaacgg aacaagccat ttggcagttt
    86881 gagtccaacg aaacgaaacc taaattatca accaaaatgc atttggccaa ccaatttcat
    86941 gttgatttaa cttattttga acaggaagaa gagagcattc gatttgattc ttctgtaatt
    87001 gcctttagaa atgcagacct agcaacacgg aaaacaatag atattcaaac tatgtattta
    87061 cataaggtag atagtttgat tgattatttt gaaagttttg taattatacc taatattaca
    87121 attcatgacc taagtaatgt agtgagtgaa tcttatcata agggagaatc cattgaggaa
    87181 ttggctcttt atgccaggga aaaattaggt atttcaaaag ataatcatga tttgctttat
    87241 aaattagaac gttcaggcat ctatatcgtg gaacgattaa ttaatggcca agctgatgct
    87301 tatagcgcat ggtcaaaatt gggaagacct tatattgtgt tgggaacgaa taaatcatct
    87361 gtacgtcgaa attttgactt agctcatgag ctaggacata ttcttttaca taaatataaa
    87421 gatatgaatg aagatggcga tcgtttggag caagaagcaa attattttgc atcatgtttt
    87481 ttattgccaa aagaagagtt tttagtcaaa tttgaagaga gggttggcaa gcgtgtcagc
    87541 aatcctgata gttatatttt attgaagtcg gatttgaatg tttcgataca ggctttagag
    87601 tatcgagctt ttaagttagg attattgact ccaaagcaac attcttactt ttatcgtcaa
    87661 attgcgcaaa aaggttacaa aatgattgaa cctttggatg atcaaatttt tgttaaaaaa
    87721 ccaagcaaag taaagagtat tctggacgtc gttttgagta atcatctagt cagtctagcg
    87781 actataatgt ctaaacaaag tattcgttta cagtttataa gcgaaatatt ttcagtcgaa
    87841 atgaaatttt ttgatcagta tcaagaagat agaagaacag atcgatttga taacatcatc
    87901 cctttgtaca aaagaaataa tttataattt aactgtgaaa taatttcatg aaggacatat
    87961 ggcagaaatt ggattttatt agacaagcag tagcttacca aaaataatca aacaagtagc
    88021 aagtaagagg aaaggcacga aaggaagtct ttcctttttc ttttgcagga gaaaggccag
    88081 gatacccgtc gcagaagcga actgaatcaa gatcagtaac tccgttacgc taaagacgag
    88141 agcacaagaa gctaaaaaaa ggaaatcccc tgcacccatg cggatatcga taaaatgagc
    88201 caaaattcca agtatgagga aggagaccat gaccagattc cagccagagg aagctattag
    88261 gattaggtgg caagtcatcc agaccagtaa gggatattcc tgatggtgaa agtcgtagat
    88321 acccaaggtc aaaccagcgg tgattaggac gacttgcccc aaggaaagca atttccaaga
    88381 gtaaagcaga aagaggagtc ctaagactaa ttcaaagagg gcataccaga caggatagcg
    88441 aactttgcag tagcgacagc gaaagcgatt gaagacctgt gagagaatcg gaatcaaatc
    88501 taagggacgc aagcgagtct gacaggaatc gcagtgactg gctgaactga taatggattg
    88561 ctctggaaaa cggtcaatga ccaaaccaag aaaggaagcg agaatgctcc cgacgagaaa
    88621 aaaataaaaa tcaatcatac ttatctattc gtaaaaaatg ggagaaatag tataatggag
    88681 aaacatagat aagatggtga ggaaaagatg acaattcgtt ttgaagaaaa ggtgagtata
    88741 gaaaacgctc aatttgtatg ccagtggtcc aactccctag gcaaatcctt tcaagaacaa
    88801 tggatgggac caaggattcc ttttctactg acccttcaag ccttggaagg agtcttttca
    88861 atctttgatg aacaagagtt tgtgggattt atccagaaaa tcaggctaga agacagcaat
    88921 cttcatatcg ggagattttt tatcaacccc cagaaacagg agcaaggctt aggtagccag
    88981 gctttaagga aatttgttag tttggccttt gaaaatgaag atatagatag tatttctcta
    89041 aatgtcttcg aggcaaatca aagagctcag aatctttacc aaaaagaagg atttgaaatc
    89101 gttcaaatgg ttgaagcacc tgtacgaaaa tatagtatat tgaaactaga atagtacacc
    89161 tctacttcta aaacattgtt agaaatcgat ttgactgtcc cgatcgattc gtcctgttat
    89221 tatttcattt tactatacat tatgaaaaag gggagatagg agtataattc caaatataaa
    89281 gaaagcgaac aaaacagaat tctgattttc agaaaacagg tttgttcgct ttttatgata
    89341 tactccctct ttttagccta tttattaaat gtaatagaaa attaggaatg tagaattgta
    89401 tgatacaaac aaagtgcaat agctgagtgt gcggctgtaa aatcattgta aggttcaata
    89461 atgacttcag gtaggcgatt atagagcagt ttgggtttgt agttcatttc actatatagt
    89521 ttttggatga tgtgttgatt tgttagtaaa ggactatgta ggtagatttt ttgagagtca
    89581 atcatcatac tgatatttaa aatggtttga ctaagataga gtaaggcttg atggataagt
    89641 gtgattattc cagtgtcacc taattgataa gcggttaaaa taacttggat atcaatatca
    89701 tcggcatttt tgactaaact aggaagtaga gaatagggag attgatgata tagaattttt
    89761 gattttttga ttaaccaaga ttctccagca aaagtttgta agcatccctt gcgcccgcaa
    89821 ctacattctt ctccctcaga tgaaacaact gtatgcccta tttctccaat cattagattt
    89881 ccttttccat aaatgtttcc gtcgtagata taagaacagt gcatacctct agcaaaatga
    89941 aaataagcaa aattagggtc attctgttgg cgactaaata ggcgtttacc tatagccata
    90001 cagttaacat tgttagagaa aaacaaaggc ttatcaaagt gggattgaat catttctaag
    90061 tcgatatgtt gccataaagg attgtttgtt gttattttat aatcatctaa atagcgacca
    90121 ggtagcgcga ttccaattgc ttctatttca taatcagagc agttatttaa gaattgcttt
    90181 agtgtctggc taatgagttg atttcccttt tcttggatta actgtttagt aacaatttct
    90241 ttctcttcct ttaagatatt tcctagatta tctcctaaag caaaagtgaa atgtttttca
    90301 gatagttcac aaccaatgta gtaaaatcgt ttagcttgaa tgtctagcag gatttttttt
    90361 ctccctacgc ttgtatcgtg ttcgtcttca ccaagttcta agagaatgtt ttctttaatc
    90421 agatcatttg tgatactgct agttgttgca ggtgttattc ctgttttagt agcgatttca
    90481 attcgtgaaa tgggacctaa tgtgtaaact gtttccagta ttttagctcg tagttgtaat
    90541 tgtttcttag ataaggtcat attagttttc ttcctagttg tcagattctt aaaatcctat
    90601 gattttttgc tatggataaa tgtagatgtt aatcttttta agcttttcat tgcttactgg
    90661 tctcttttta ttatatattg ataataaaaa ataatcaaat atttacacaa atccttgaca
    90721 aggctttctt atagttgtaa aatataaata acaaaagata atcaaataac aacttgacgt
    90781 caaaaaataa agataattga taacttttga taataaaata tatttaagag gaaaaggtta
    90841 tggaaaaatt attacaagaa aagttacttc cagtagcggc tagattgggt aataataaag
    90901 cgttggtttc tattcgagac ggtattactc taactatacc tttattgttg ataggttcat
    90961 tactaatggt tattgcaagt tttcctattc caggatggga aaaatatctg ggtgatattg
    91021 gtgttgctga ctatttatgg aagggtgttg atagtagttt tggattactt ggtcttgtag
    91081 ctagttttgg tatcgcttac tttatggcta gacaatacaa agttgatggt attcctgctg
    91141 gtattgtgtc attatcatct tttattacag ttacgccttt cattagagga gaggctggag
    91201 caggaatgcc taccgctttc atggcatcaa aaggtttatt tgttgctatg attttaggat
    91261 tgattaatgg ctatatctac caatggttta taaatcataa tatacagata aaaatgccgg
    91321 atggtgttcc accagcagta tctaaaagct ttagtgccat tattcctggt gcagtgacta
    91381 ttgttggttg gttgattgtt tatgcaactt tagataaatt aagtttacct aatcttcatg
    91441 aaattgctca agtagctttg ggaggtccac ttggactttt aggaaataat gttattggtc
    91501 ttcttatctt aattttcctt aatagtagtt tttggtttgt aggattacac ggaggaaatg
    91561 ttgttaatgc agttatgaaa ccgttatggt tagctaatct agatgcaaat aaagtagctt
    91621 atcaaactgg agaaactctt ccaaatattt ttactagcgt atttatggat aattttgtat
    91681 tcataggtgg cggtggtgca accataggtt tagttcttgc gttaggatat ttagcacata
    91741 agaagaaagc tagtaaacaa ctaaaaactt tggcacctat aactgttata cctggattat
    91801 ttaatataaa tgaaccagca atgtttggcg ttcctattgt tttgaacatt ttgttactag
    91861 ttccatttat cttagctcca atgtttaact tactagtagc gtggggagca atggcatcag
    91921 gtttggttcc gctaacttat acagatccag gttggactat gccacctgtt ataagtggtt
    91981 tacttgctac aggaagtatt tctggttcat tattacaaat tgtattgatt gttttggatg
    92041 tcttacttta tttaccattt gtaatagcta ttgaaaaacg gtttaagtta ttggaggatt
    92101 gagaatgaaa cgtttaatta gtgcaaatcc atctgagata ttacagatga atgctgaaga
    92161 attaaaacaa agtattttag caagtgaagg tagagttgtt ctatctgaaa atgtagttac
    92221 tcgtgagaca tttgttgggg atataactaa ttctgaaatt gctagagctt ttggagctga
    92281 tatgatttta ttgaattgtg ttgatgtttt tgagcctaaa atttatgctt tggatagttc
    92341 aggtgatgat gttattcatc gcttacacca gcttgttgct tgtccaattg gtgtaaattt
    92401 ggaaccgatt gacccatctg caaagatgct agaggaaaca caggaaattg ttgcaggtcg
    92461 tgttgctagt gttgaaacat tgaatcgaat agaggagtta ggttttgact ttgtctgttt
    92521 gactggaaat cctggaacag gagttagcaa tcgagaaatc attaaggctg ttcaaactgc
    92581 taaggaaaac ttttctggtt tgattattgc aggtaagatg cacggggcag gagtgaatga
    92641 gcctgtggca gagctttctg tagcagagca attgttggaa gcaggtgcgg atgtgatact
    92701 tgttccagca gttggaaccg ttccagcctt tcatgaccaa gagttgcgtg aagtcgttga
    92761 tctcgttcat agtaagggtg ggctagtact gagtgctatt ggtactagcc aagaaacatc
    92821 tgatacagat actatcaagg aaattgcact tagaaataaa atttgtggag ttgatattca
    92881 acatataggt gacgcaggat atgggggact ggcaacagtc gataatattt atgcattgag
    92941 caaggcaatt agaggagtga gacatacagt atctcgcttg gctaggtcag taaataggtg
    93001 ataaaggagt aagctatggc taaagtaaca attatgttag catgtgcagc aggtatgagt
    93061 acaagtctgc tagtgacaaa gatgcaaaag gcagcagaag ataaggggtt ggatgcagaa
    93121 atttttgcag ttccagctcc tgaagcagaa gaaattgtag caacaaagga agtaaatgtg
    93181 ttgcttttag gccctcaagt tcgctattta ctaggggact ttcaagaaaa actaaaagat
    93241 agacagattc ctgtggcggt tattccgatg acagattatg gaatgatgaa tggttctaaa
    93301 gtcttagatt tagctgaaag tttattagac taagattgag gagaatgcta tgaatgaaag
    93361 taatttagaa tctgcaatgg ggctaattat gtatggtggg gaagccaaaa gtaatgctat
    93421 ggaggctatt caggcagcaa aaaaagggga tttctctaaa gccaatcgaa gattagctga
    93481 tgcgaatgct gccttattac aggcgcataa ggctcaaaca gaaatgttga caagagaggc
    93541 acagggggaa gaaacttcaa ttagcctctt gatggtacac gcgcaagatc atttaatgac
    93601 gagtctgacc tttgttgact tggcgaaaga agtggtagaa gtatacgaac gatttgaaaa
    93661 aaattaggaa tttgctatga atacaatgtt ggataaaatg caagaaaaac tttctccaat
    93721 tgcaatgaaa gttgggaatc agaagttttt agttgcttta cgtgattcat ttgtggggac
    93781 tatgcctgtt attatgacag gttccattgc tttgttatta aatgcttttc tagtggattt
    93841 accacaacaa tttcacctag aaagtattac gaaaaccttt cagtggcttg ttgacatcaa
    93901 taatttggta ttcaagggaa gtataccaat tgtttcctta ttgttcatct attgcttggg
    93961 agtgaatatc gctaagattt acaaggttga tacagtttct gctggtttgg tatcacttgc
    94021 ttcgtttgtc atttcgattg gaagtacagt tacaaagagt ttccctttgg caaatgtagg
    94081 agatgtgaaa ttaaatcaaa tcttacaagg aattgataat ctagcatttg atggtaaaaa
    94141 tctgatggta actattggga atgtgattcc aggaaaccat attaatgcca gaggatactt
    94201 tacagccatg atgattggat ttttagcctc tattattttc tgtaaagtaa tgaaaaagaa
    94261 ctgggtaatc aagttaccag attcagttcc ccctgcgatt gctaagccgt tcacttctat
    94321 cattccagga tttatggcga tgtatatagt agccatcttg acttatgttt tccatttact
    94381 tagcaatgac ttattgattg attgggttta caaggtgtta caaacgccat tactaggttt
    94441 gtctcaaagt ttctttgcag ttattctgat gatctttttg aataagttat tctggttttt
    94501 tggtctccat ggaggaaatg tattggctcc catcatggaa gggctatttg gagttgctat
    94561 gttagcgaat ctggatgctt tccaaaaagg tgaaccgatt ccttatatat ggacaagtgg
    94621 gtcttttggg gcgtttgtct ggtttggagg attaggatta gtacttgcta ttttaatttt
    94681 ttcaagaaac agtcattatc gaaaagttgc taaacttggt ctagcaccag ttctgtttaa
    94741 tattggtgag ccggtcaatt atggtttacc agttgtcttg aatcctttgc tatttatacc
    94801 atttgtactt agcccggttt tcatggcaac ggtagcttac tgggcaacaa gctggggtct
    94861 tgtttcacct gttacacaaa atgttacttg ggtaatgcct ccaattttat atggtttctt
    94921 ctctacagca tttgattggc atgccatcat cttatcagtt gtttgtttga ttattagtgt
    94981 cttgacttat ttcccatttg tgaaaatggc agataaaact gaattgagtt aatggtctta
    95041 cttgcgtttt ttgtgataaa atagaaatag attacgtgta agatgagtta ggtgtaggat
    95101 ttcttatctc cactaaaatt gttaatagac aaaggtttat agtttattga agttggaata
    95161 gtacactgta acttctaaaa cagtactaga aaatgatttg aatttcctaa tcgatttagt
    95221 catattttag ttcattttta tataaaacat aacaagaatg ttattgtttt atatagagag
    95281 attgatatag aaaggggtgc agtaaaggta gatatcttct tgtgcctctt ttgccatatt
    95341 agaaaggaga ttttatggtt cagacaaaac agccaaatat tattttgatt gttgtagatc
    95401 aaatgagagc agacgcctta tccttgaata gtaaggataa gctagttagc actccaacat
    95461 tagatatgat ggctagtgta ggttataatt ttgaaaatgc ctattctcca gttccttctt
    95521 gcgttcctgc tagggcagct ttattgactg gcttagacca agataaaagt ggacgtgttg
    95581 gttatcaaga tgaggtgcct tggaatttta ctaatactct tccaaaagtc tttaaagata
    95641 tgggttatca aacagagtgt attggtaaga tgcatgtttt tccttccaga cagagacttg
    95701 ggtttgatca tgtcttactt cacgatgggt atctacatgt tgatagaaag tatgataagg
    95761 cttatggaag tcaatttgat tatgctagtg actatctagc ctttttaaag ggtaaagttg
    95821 gttatgatgt tgatttgatt gatgacggaa tggattgtaa ttcttgggaa gctagacctt
    95881 gggataaaga tgaaaagtta catccaacaa actgggttgt gagtgagtcc atttcatttt
    95941 tacaaagaag agatccaacg gttccttttt ttctcaaaat gtcttttgaa aaaccacatg
    96001 ctccattaaa tcccccaaaa tactattttg atatgtatat ggaacgcttg cctcaatttc
    96061 tcgatttgca tatcgggaat tgggaagtat tagaaaagca aattccgtct atttatgctt
    96121 taagagggaa attaaaggaa gatgatcaaa gaagaatggt tgctgcttat tttggattga
    96181 ttactcatat agaccatcaa attagtcgct ttttgactgc cctaaaagaa tttcgtcatg
    96241 ataaagatac gattatctgg tttgtttcgg atcatggaga tcagcttggt gaacattatc
    96301 tgtttagaaa gggatatcct tatcagggaa gtatccacat tccttcgttt atttacgatc
    96361 cggctggatt gatagctggt aataggggaa caatcaagca attagtgaaa attcaagata
    96421 tttttccttc actcgtggat ttggcaggag gaactactac agatgaacta gatggacgga
    96481 gtgttaagaa tttattattt ggacagtacg aggggtggcg aacagaattt catggtgaac
    96541 atgctttagg aaaagattct agtcaatata ttttgacaga ccagtggaaa tttatctggt
    96601 ttcctgtttt aaatcattat cagttatttg atatgaaaaa agatccgcat gaaatgaatg
    96661 atttgtatcc aagtgaaaaa taccaaccta ttgttcgtca gatgaagaaa aaattagtaa
    96721 actttcttag atatagagaa gaaggttttg ttgtggatga agagttagtt cctgttgaac
    96781 tttctaaaat aacgccaact ctaacgaaaa cgggggatag tcaatcatga aaatgaaaaa
    96841 aatcaagggt gggacattta tgatgggaac aaattctgaa gagggctttt tagataattt
    96901 tgaagatcct caagtcgctg ttagtgtaaa ggatttttcc attgcggata ctccagttac
    96961 gaatcaagaa tttgctcaat ttgtgaaaga aacaggctat aaaacactag ctgagcgaca
    97021 agagtggtct tttgttttta tattgttcgt tccggaggca gaaagggagg gatatcctca
    97081 tcctgccggg gctccgtggt ggttacaagt tccgaacgct tgctggaaac atccctacgg
    97141 tgagaacagt aatctagtgg gtttagaaga ccatccagta gttcatgttg ctttagaaga
    97201 tgcattggct ttctgtaatt ggagcggaat gtctttaccg actgaagcac agtgggaata
    97261 cgctgctaga ggaggaagac aatctgaata tccttgggga gatactcttt tagaaggtgg
    97321 atattatcat gccaatactt ggcaaggaag atttccttat gaaaatactg gcttagatgg
    97381 atttatagga acggctcctg tctatgaatt tttacctaat gattttggtc tatatcaaat
    97441 gattgggaat gtttgggaat ggtgtcgcaa tccgagatat accttattag ctagttttaa
    97501 tgaagatgac tatgagttgc caaaatatgg gatacaagat gaggagtatg ctatcagagg
    97561 aggttccttt ttatgtcatt gttcttattg taatcgatac cgagtagctg ctagaaatgg
    97621 atgtatttct acttccacta gtagccatct aggttttaga tgtttgaaag aataggatgg
    97681 acttaaaaag tggttgagat tatttatttt ctaatcatta taatagctag tggattgggt
    97741 tctatatcag gcatgggtgg tggaattata attaagccac ttatggatag ttttggatac
    97801 cattcggtca gtgatattgc tttttattct agtttctctg tttttataat ggcgattatt
    97861 tcaacaacca aaagattttc acaaagtaaa gagataaaat ggagattgat ttttacggta
    97921 tccttttctt ctgttttagg aggatttcta ggtcatctta tttttcaagt tttgttatct
    97981 caattatcag tacggctagt atccattgtt caaatgattt tactatttgt gatgctactt
    98041 gtatcatttg ttttaacaga ttttaaaaaa acttatcaat ttgataagat aggattctat
    98101 atgatttgtg gtcttctatt gggcttgatt tctagttttt tagggattgg tggaggtccg
    98161 ctcaatgtat ctttattgat ggtgtttttt tctatttcga taaaagaagc aacgatgtat
    98221 tctcttgcaa ttattttctt ttcccagctg tctcatttgg ctacaattgt tgtggttaca
    98281 ggtttaaatc agtatcattt agcacctgtt ccagttattt ttcttgcttc tatatgcgga
    98341 ggggtattgg ggacggttgt atcaaaagtc ttacctgaaa attgggtaag atactgtttt
    98401 aaagggatgt tattctttgt catgggaatg actttatata atttatttca tattttgtaa
    98461 ggtcagtgtg aaaatattta aatagacttc ctgtaaaaac tggatttaac gccctccatt
    98521 tgtcaaatta agctagacag tcttaccaac tcagaaaata acctgatgag gtatttggta
    98581 tccaaaggat ttaggtggga tgtgatttct tgaggctggg aaaaagtctt taaaattaaa
    98641 aaatgcataa tatcaggtgt tggaaaaact ttgatactat gcgttttatt gtgggaatat
    98701 ttatttcatt ttctcctgaa attgagttct tgcccagcct aaaattcttg actgacttcg
    98761 ttgaaatctg tctgctttgg caagtcatga caccttaaaa gtctatttga atgttcgttg
    98821 agacaccgct atcttggaca tcctagattc gcaaaaaagc tctcactatc gtgatgattg
    98881 gaaatatctt tccattttga aaactctttt ccacagtcaa acgtaataga tttaaagagg
    98941 ttcactagaa attgtgccag ccacccttgg atggattctg ccatatcctt tgccttacga
    99001 ctcttggtct tcaaactgac aatcaattga ctatacctgt tcgctcacaa ataggagaga
    99061 actttttacg aaaatctaat gaatatgcca caagaacatt ataccgcaac gtgtactatt
    99121 tttggttcat tttactatag aaactattga agcacctgta cgaaaatata tcatgaaaaa
    99181 ggggagatag aaagcaaaca gccttgaaat caatgttgac tgcgattatg aacctgaatc
    99241 agcccctcaa aagggactgt atatgaatga acgttaccag tgtttaaaaa ctaaagaata
    99301 tcaggcactt ttatcttcca agggtagaca aattttcgct aaacgtaaga ttgatatgaa
    99361 atctgtcttt gggcagataa aggtttgttt gggttataag agatgtcatc tgagaggtaa
    99421 gcgtcaagtg agaattgaca tgggattcat actcatggcc aacaacctgc tgaaatataa
    99481 taagagaaag aggcaaaatt aaaaagctag agttccgcaa ttgggaatct ctagcttttt
    99541 gttttctgag aatcatcttg actcagactc ttttgactaa tgttactaaa aagataaagt
    99601 aacttttaac cttatttatc gtcgccactc aacatgtttt taacaccttc tacagcacct
    99661 tctacagcac cttctacagc gtctttggca tcttcggcga cttcttttac tttagaaaca
    99721 actttttcag ctgctccttc tttttccatt ttttcatcac cgatggcttt cccaacacct
    99781 tctttaatag aacctttagc ttgatttaat ttttcttcta ctgacatgat aatttctcct
    99841 gttatattta ttttatctta gtttacacga gtgttttcgt gagatactac accatttgct
    99901 gcacctttaa cagcttctac accttcgcta actttttctt gaacagttga gaaaccagat
    99961 ccaagaccag atttagcttt ttcgaattgt tctgaagtga attctcctgt tgattcagca
   100021 acgtcagata cgcgatcttg aaggcttact gagtctgctt catgctgttc tttagttttg
   100081 atgtcgacaa cgtttacgtt gatttcaaca atttccaagt cagtcatttt agcaacttct
   100141 gaagatacga tttctctgat ttctgaatat aaagctggaa catttttttg gtactcaaca
   100201 ataacgttta agtcaactgc aacttgtgtt ttaccaactt ctacgttaac accacttgtt
   100261 acgtcatcgc tgttaacgat tttttcttta agatttgaga agaaaccacc atcgattccc
   100321 aaaagacctg aaacgttttc tagtgaaaga ccaatgattt tttggataac tttatcttcg
   100381 taagtaagtt cccctttgat ttcgtgagct acaacagtag catctttctt ttctacgtta
   100441 gtgtttgtgt ttttttcgtt tgacatatga aactccttta attaaattag taatttttat
   100501 ttttttattt atctatatag tttttttcga tatataatcc agctgcaact cccagtgctc
   100561 ctaaaatcaa tacaaatatt gttttgaaga agccaaagga gacaatcaaa caagccagaa
   100621 atacgcctat gagaccagcg ataattggat atcgatattg tttaagccat tccatttttt
   100681 acttccttac ttcacacgac taacagtctt tttgttttga ggttttggtt ggtaattttt
   100741 tactgcaact tcaagtttta cttgacgctc aataccaaaa aactgcttca atccattagt
   100801 tatttcattt tgaattattt ggcatctgtc agcgatgttg tctgaaggaa gaattttacc
   100861 ttctacatga acgaaacatt tattttttcg taaatttaca tgaacagttg ggttcttgat
   100921 caatctatga tcactcacca aacttctaac aaaaccttcg attgccgaat tctttaattt
   100981 taatgtatcg tttttagttt caagttggat ttccaagtaa cgtttaggat aaaacatcac
   101041 aactaaaatg gataataaaa ctaaagttga tagaaccact gtcccccaaa agacatatct
   101101 agcaagatag aattcaacta cggagttctg tctccagcta agtagatgaa tacctagatc
   101161 actaacttga tgataatcta tcaaaacagg aaggaaaatt gtcaagatta aaatacagaa
   101221 aataatgaaa catattttct ttgcttttga catatacaat cctttcgatt taacatttaa
   101281 actatttttc ccgtcattga tttaaaaata gtttgctaac tttactggcg aaaagtttac
   101341 tttctacctg taaagaatga cactacagta atcacaatcg ctgcacctac aatagatggg
   101401 agcaaagcca ttccagcgat tgatggaccc caactaccta aaagagattg tcctgcatat
   101461 gccccgacta aaccagcgaa tacatttgcg atgattccca tagaactact tttttagtga
   101521 ttttacctgc caagagacca ataagacctc cagcaataat tgatcacaac actgcctacc
   101581 ctcctttttt attttaatat caaaaaatca atttctttga ttaatactat tatataactt
   101641 taatatagaa aagtcaatta tttcgattgt tattattata taattttaaa aaatcaaatt
   101701 ctttaattgt tgctattata taatttttaa aattaaaaat ataatcttta gacttgaatt
   101761 tgattctgta ttcacgccct caatagacgg taaaataaga aaattgttta tatattgtct
   101821 ccgtagtgtt attatacgaa ataaaagatt ttaggaaaag tcgttatatc atgctatacc
   101881 tattctttgt ggtataattg caagaggttt aatccgataa tttataaaga gagaaagata
   101941 ttcatgagag atttattatc taaaaaaagt cataggcaat tagaattatt agaattatta
   102001 tttgaacata aacgttggtt tcatcgttct gaactagcag agttattaaa ttgtacagaa
   102061 cgtgcagtca aagatgatct atcccatgtt aaatctgctt ttcctgactt gatttttcat
   102121 tcttctacta atggtatacg cattattaat accgatgata gtgatattga aatggtttac
   102181 catcatttct ttaaacattc aactcatttt tcgattttag aattcatctt ctttaatgaa
   102241 ggttgtcaag ctgagagtat ttgtaaagaa ttttatatca gttcatcttc gctctatcgt
   102301 attattagcc aaatcaataa agtgattaaa aggcaatttc aatttgaagt cagtctgacc
   102361 cctgttcaaa tcattggaaa tgagagagac attcgttact tttttgcaca atatttttca
   102421 gaaaaatatt atttcctaga atggccattt gaaaattttt catcagagcc actatctcaa
   102481 ttgttagaat tggtttataa ggaaacaagc tttccaatga atttgtcaac gcatagaatg
   102541 ctaaagttgc tcctagttac gaacctatat agaataaagt ttggtcattt tatggaagta
   102601 gataaagatt cttttaacga ccaaagtttg gattttttaa tgcaggcaga aggaatagaa
   102661 ggtgttgctc agagttttga atcagaatac aatatctctt tagatgaaga agttgtttgc
   102721 caattatttg tgtcttactt tcaaaaaatg tttttcatag atgaaagtct ctttatgaaa
   102781 tgcgtaaaaa aggatagtta tgttgaaaaa tcttaccatc tattgagtga ttttattgat
   102841 cagatttcag tcaagtatca gattgaaatg gagaataagg ataatctgat ttggcatctg
   102901 cataataccg cacatctgta tcgtcaagag ttgtttactg agtttatttt atttgatcaa
   102961 aaagggaata caatcaggaa ctttcaaaat atttttccaa aatttgtttc agatataaaa
   103021 aaagagcttt ctcactattt agagactctt gaggtttgtt ctagttcaat gatggtaaat
   103081 catctatctt ataccttcat cactcatacc aaacatttgg tgattaattt gctacaaaat
   103141 cagcctaaac taaaggtttt agttatgagt aattttgatc agtatcatgc aaaattcgtt
   103201 gcagagacac tttcttatta ctgtagcaat aattttgaac tggaagtttg gactgaatta
   103261 gaattatcaa aggaatcttt agaagattca ccttatgata tcattatttc taattttatt
   103321 attcctccta ttgaaaataa gagactcatc tattcaaata atataaacac ggtctcactc
   103381 atatacttgt taaatgccat gatgtttatt cgattagatg agtaaccaaa aataacaaaa
   103441 aaacgctatt tcgcgtttga actgtacctc aaaagttaga cagaaaaaat ctaatttttg
   103501 gggtgttttt gttaagaaaa gaccttcaat catttaagca aaatgtacat ctagatttat
   103561 agccctctaa aactcttgct ttttttgtag aagatacgaa aaaagccata aaaccaaggc
   103621 ttttcctgtt ttatgtagat gtttacacat gaaaattgaa gtattttcaa aagctaattg
   103681 gagtgatttt attcatgatg ggataaatga tctggccaaa aatgattgag aaatagttgc
   103741 ttaaaaagca tttgcatgat actatatatt gaaaggaggt gataatatgg tagaacaaag
   103801 aaaatcaatt accatgaaag atgttgcttt agaagcagga gttagtgttg gaactgtttc
   103861 acgtgtaatt aataaagaaa aaggcattaa agaagtaact ttgaaaaaag tggaacaagc
   103921 gattaaaact ttgaattaca ttccagatta ctatgctaga ggaatgaaaa aaaatcgaac
   103981 agaaacgatt gcaatcattg taccaagtat ctggcatccc ttcttttcag aatttgctat
   104041 gcatgtggaa aatgaagtct ataagagaaa taacaaatta ctcttatgtt ctataaatgg
   104101 tacaaataga gagcaagact atctggagat gttgcgtcat aataaagttg atggagtggt
   104161 tgccattacc tatagtccaa ttgaacatta cttgacgtca ggaattccct ttgttagtat
   104221 tgaccgcaca tactcagata ttgccattcc ttgtgtttca tcagataatg atgcaggtgg
   104281 aagagaagca gctaaacaat taattagtaa aggatgtcag catttagcct ttgtgggcgg
   104341 acataataca accattaatg aaaccaaacg tcgtagaatt tcatttgaaa agtatgtcca
   104401 agagcataaa atacctctta gtatttttga tttggatgag aaagttactg actattatgg
   104461 aaagctagag agtttcttgg aagaaaattc ttctatagat ggaattttta caatcaacga
   104521 ttttacagct ttggatgtga ttgaaatact agaaaaaaat ggcaaacgta ttcctcatga
   104581 tgtccaaatt attggatacg atggaattaa aatggctgga gatagagatt atctactttc
   104641 aactattgaa caaccattgg aagaaatggc aaaagaagcg gttcgtattt tgtttgatat
   104701 aattgatgga aagactgtta atttgcagac aatcctacca gtaaaatttg ttgaaggaaa
   104761 aacaacaaaa aatgaaaata agtcttgaca gaaagcgcta tcaatgatag aatgaattca
   104821 gataaaaaga tttattttta aaacaaaaat gaaacgtttc aaaaaaagaa ataaaaagac
   104881 agcgccaagc gctatctttt atagaaaaaa tgaaacgttt caaaaaaagg aggttgctat
   104941 gaatagcaaa gcgaagcaag tttctctttg ggaaagaatc aagaaacaaa aactcttgtt
   105001 attgatgact gtccccggtt tagttttaac ctttatcttt aaatacatcc ctatgtatgg
   105061 ggttttaatc gcatttaaag attacaatcc tttaaaagga attttaggga gtgattggat
   105121 tggtttttct gagtttacaa aattcatatc ctctcccaac tttggtatct tgttagccaa
   105181 cacattaaaa ttaagtatct atggtttatt gcttggcttt ttaccaccaa tcattcttgc
   105241 gattatgctc aatcaactct tgagtgaaaa agtcaaaaaa cgaattcagc tcattttata
   105301 cgcaccaaac tttatctcag tcgttgttat tgtcggtatg attttcctct tcttttcagt
   105361 gggaggacca atcaacaatt ttctttctat gtttggaatg aaggctgact tcttgacaaa
   105421 tccagacttc tttagaccct tatacatctt tagtggtatc tggcaaggaa tgggctgggc
   105481 ttcaacgctc tacacggcaa cattggtaaa tgtagatcca gccttagtag aagcagttcg
   105541 actggatgga gccaatatct tccaacgaat ctggcacatt gatattccag ctcttaagcc
   105601 tattatggtt atccaatttg ttttagctgc aggtggaatt atgaatgtcg gatatgaaaa
   105661 agcattcttg atgcagacat cgttaaattt gccaacttct gaaattatct cgacatatgt
   105721 ctataaagtt ggtcttgtat caggagacta ttcttactca acagcggttg gtttgtttaa
   105781 tgcagtgatt aacgtagtat tgcttgttgc agttaaccaa atcgttaaac gcatgaataa
   105841 tggtgaagga atttaaggag gaaagtatga aaaattcgat tatggataca aaatttgata
   105901 gacgtatctt actcttaaat aaaatcatta ttgtctttat cgttttgatg actttgcttc
   105961 ctttacttta tatcgtcgta gcatccttta tggatcctaa ggttctggtt agtagaggga
   106021 ttagctttaa tccagccgat tggactgtag aaggttacca gcgtgtattc agtgaccaat
   106081 ctattctaag aggttttatc aattctctac tatactcttt tggatttgca gctttaacag
   106141 tattgctatc tgtgtttaca gcttatcctc tttctaagaa agacttggtt ggacgtcgtt
   106201 ggattaacta cttcttgatt gtgactatgt tctttggtgg tggtttagtc ccaacttact
   106261 tgctcgtaaa agaattggga atgctcaata ctccatgggc tatcattgtt ccaggtgctg
   106321 tcaatgtttg gaatattatt cttgctaggg cctatttcca aggattgcct gaagaattag
   106381 ttgaagctgc tgtcattgat ggagcgaatg acttgcagat tttctttaaa atcatgcttc
   106441 ctcttgcaaa accaattatg tttgttctct tcctctatgc ttttgtagga cagtggaact
   106501 catactttga tgcaatgatt tatatcaagg atccaaactt ggaaccattg caacttgtac
   106561 ttcgtaaaat tctcattcag agccaaccag gtcaagacat gattggagca caagcggcta
   106621 tgaatgaaat gaaacgttta gctgaattga ttaaatacgc aactattgtc atttccagct
   106681 tgccattgat tgttatgtat ccattcttcc aaaaatactt tgataaagga attatggctg
   106741 gttcacttaa aggataaaaa aagaaaaaat aaaaggagtt ttctcatgaa attcaaaaca
   106801 ttctcaaaat cagcagtttt gttgacagct agtttagcag tacttgcagc ctgtggctca
   106861 aaaaatacag cttcaagtcc agattataag ttggaaggtg taacattccc gcttcaagaa
   106921 aagaaaacat tgaagtttat gacagccagt tcaccgttat ctcctaaaga cccaaatgaa
   106981 aagttaattt tgcaacgttt ggagaaggaa actggcgttc atattgactg gaccaactac
   107041 caatccgact ttgcagaaaa acgtaacttg gatatttcta gtggtgattt accagatgct
   107101 atccacaacg acggagcttc agatgtggac ttgatgaact gggctaaaaa aggtgttatt
   107161 attccagttg aaaatttgat tgataaatac atgccaaatc ttaagaaaat tttggatgag
   107221 aaaccagagt acaaggcctt gatgacagca cctgatgggc acatttactc attcccatgg
   107281 attgaagagc ttggagatgg taaagagtct attcacagcg tcaacgatat ggcttggatt
   107341 aacaaagatt ggcttaagaa acttggtctt gaaatgccaa aaactactga tgatttgatt
   107401 aaagtcctag aagctttcaa aaacggggat ccaaatggaa atggagaggc tgatgaaatt
   107461 ccattttcat ttattagtgg taacggaaac gaagatttta aattcctatt tgctgcattt
   107521 ggtatagggg ataacgatga tcatttagta gtaggaaatg atggcaaagt tgatttcaca
   107581 gcagataacg ataactataa agaaggtgtc aaatttatcc gtcaattgca agaaaaaggc
   107641 ttgattgata aagaagcttt cgaacatgat tggaatagtt acattgctaa aggtcatgat
   107701 cagaaatttg gtgtttactt tacatgggat aagaataatg ttactggaag taacgaaagt
   107761 tatgatgttt taccagtact tgctggacca agtggtcaaa aacacgtagc tcgtacaaac
   107821 ggtatgggat ttgcacgtga caagatggtt attaccagtg taaacaaaaa cctagaattg
   107881 acagctaaat ggattgatgc acaatacgct ccactccaat ctgtgcaaaa taactgggga
   107941 acttacggag atgacaaaca acaaaacatt tttgaattgg atcaagcgtc aaatagtcta
   108001 aaacacttac cactaaacgg aactgcacca gcagaacttc gtcaaaagac tgaagtagga
   108061 ggaccactag ctattctaga ttcatactat ggtaaagtaa caaccatgcc tgatgatgcc
   108121 aaatggcgtt tggatcttat caaagaatat tatgttcctt acatgagcaa tgacaataac
   108181 tatccaagag tctttatgac acaggaagat ttggacaaga ttgcccatat cgaagcagat
   108241 atgaatgact atatctaccg taaacgtgct gaatggattg taaatggcaa tattgatact
   108301 gagtgggatg attacaagaa agaacttgaa aaatacggac tttctgatta cctcgctatt
   108361 aaacaaaaat actacgatca ataccaagca aacaaaaact agaggttgat tatgggagat
   108421 aagaaataca cagtagaaaa agccaatcgt tttatagcag aaaataaaca tctcgttaat
   108481 actcaatata agcctgaaga acatttttca gctgagattg gttggatcaa tgatccaaat
   108541 ggatttgtct attttcgtgg agaataccat ctcttttatc aattctatcc atatgatagt
   108601 gtttgggggc ctatgcactg gggacatgct aaaagtaagg acttggtgac ttgggagcac
   108661 ttgccagtgg cacttgctcc tgaccaagat tatgaccgaa atggttgttt ctcaggctct
   108721 gccattgtca aggatgatcg cctctggctc atgtacactg gacatatcga agaagaaacc
   108781 ggtgtccgcc aagtgcaaaa tatggcattt tcagatgacg ggattcactt tgaaaagatt
   108841 gaacaaaatc cagttgcaac tggatcagac ttgccagatg agttgattgc tgctgatttt
   108901 cgtgatccaa aactctttga aaaagatgga cgctattact ccgtagtagc tgccaaacac
   108961 aagaataatg tgggctgtat cgttctacta gggtccgata acctagtaga atggcagttc
   109021 gaatccatct ttttaaaagg ggtagaacac caaggcttta tgtgggaatg cccagattac
   109081 ttcgagttag atgggaaaga ttgccttatt atgtcaccca tgcgttatca gcgtgaggga
   109141 gactcatatc ataacatcaa ctcatcgctt ttgttcacgg gtaaggtaga ttggggagaa
   109201 aaatgtttta tcccagaatc agttcaagaa attgatcatg gccaagactt ctatgcgcct
   109261 caaacattgt tggacgatca aaatcgtcgt atcctgattg cttggatgca gacatggggg
   109321 cgtacccttc caacccatga ccaagaacac aaatgggcat gtgccatgac tttacctaga
   109381 attttaagat tggaagatgg caaactaaga caattccctg ttaaaaaagg ccaatatcaa
   109441 atccaaatag ataaagattg tcattaccac ttaggaaatg atatagatta tcttgaattt
   109501 ggttatgata gtaatgcgca gcaagtttac attgatcgta gccatcttat tcaaaaaatt
   109561 ctaggtgaag aagaacagga cactagtcga cggtatgtag atattgaagc taaagaattg
   109621 gaagttgttc tagataaaaa ttccatcgag atttttgtca atcaaggtga agcaagcttg
   109681 actgcaactt attacttaac ggtgccagct gagctatcac gaattgatta aaaattaagt
   109741 tatttctcct aaagaaaaag ttctctttct aaaatagtgg aaagaggact ttttgtgttt
   109801 tgggtatata agcttagttt atggtatttg taaaattggt gttggattat gatttaagct
   109861 agttttctaa agaatttgaa aaaaatttta tttaagcaaa aaaaaccctt ggttccaagg
   109921 cttttcctgt tgtatttata tgccccctac aagtatatta tgatacatag tattaagtga
   109981 ttatttattt ttgaggcttt tcttattcta aaagtaggta tatgagttta tggacattgt
   110041 aattcacaac aaattcacgg cagaaaatac aattaggtag tttgtaattt taaaattaat
   110101 gcgaaactaa ttaaatttaa aaaaaatcaa ctttcttcct tgaccttttt aaaaaatttt
   110161 ggtatactta atgggtaatc aagattgaac aaagaatcaa gctttttcaa cttgcaaaat
   110221 tatcagaaag gaggctctat aatgaggatt caaatgagat tatctaaaga agctcgcgtt
   110281 gttttagaag aattaaaatt agaatattta aaaaaaggtg aagacaaaac atcaggagta
   110341 atcgttgatg aaatttttaa acattttagt tctaattttc aaaaagtaga ttggaaatct
   110401 gttcaaagtg cacctaagtt taatgaaatt ttggcagatt atacttcagt taatcccaca
   110461 acacttaatt tatctaatag tacaataagt acaatgtctt acattagaga ccattttaac
   110521 tacatattag atatgaaaag aaccgtctat cgttcattca taattcgcct agtcttgaag
   110581 gcttacaaat tagagaagga aggcaccgat atttatttat aatagatgtt tatttcatct
   110641 attataattt tagcatgatg agtagtcaaa actatatcta aagggaggtt aatctctctc
   110701 tttattttta aaatttgaaa ggaaaaatac aaaaatgaaa attaatgaat atttatggag
   110761 aacgagctgt cttatactgc taattatcat gagcttcttt gcaggcttcg gagctaaatt
   110821 agagtttaca tcttataacc cgtttttatc tgttaaattt ggtttggtcg tagctctgac
   110881 agtctttgta gttcaattgt tagccatact gccagccatg gttaaaagag gaaataaaaa
   110941 tgagaatgtt gaatcaaaca attcgtgtga agagtaaata cccttacttg attcgtcccc
   111001 gaaatattaa aattgtaaga ttgtttatcc aaatttttgt ctttttactc ttaatatctt
   111061 cgtggattgc tataatccca tttattgctc gtctagtctt ttccatgttt tttataagtc
   111121 ttcttttttt cgtagagaag ttctttcgtt ctaattttat agcaaaattg agaaacaagc
   111181 tcaatatcag agaagccttg ttttacatgt taattagttt aaatttatat gatgagctcg
   111241 ataatgaagt agtagataca gcagttttat attttgacgt tgagaataat aaagttgttg
   111301 tctgtgcccc actatttggg aaccgttatc tgaaaacctt gaaaaattta gaggaatatc
   111361 tctgtcccac tttgggcttg tccttgctgt ctaaaaaaga agaaatcgat aaaatagtat
   111421 acgtgttagg gcagaaagaa gaaatagaac aatatgtttt taatagtaac acattaacaa
   111481 gagaattttt taaagatatt cctagttcaa taatcaagct gtcaaataca cagaaattta
   111541 gtctaaagtc caacactaac ctaggtatat atggaagaac ggggacaggc aaaacaatag
   111601 ctctgcaatg gtacttattt aacgcactgg ctaaaggttg tggtattgct gataatactt
   111661 atttaggcat agtagatggt aaggcagctg acttgtatcg tattggtgaa cttcttcacg
   111721 aagaactggg agaacaagtg gcagtaggct cttcaccaca aatgcttgcc caattatcga
   111781 gaaaattcat tgagaatatg gatgcaagat ttaaaattat caaacagaat agttcattga
   111841 atgctgacat ttatgagcta gatgagctgg gactggtacc taattttttg ttcgttgatg
   111901 aactcgcttc tattcgtgat agttgtggct ctacgaaaca aggtagagaa acatggaatg
   111961 aaattctaca aaatttaggc ttgattgcac gcaaaggacg gcaggcaggt tgccacctag
   112021 tcctatctac tcaagaccct aatgccgaaa acatccccgt tgaattgagg aatcaaattt
   112081 cagcagtttt ataccttggt gccccagggg ctgatagatt gaagatggct tttagcatgt
   112141 gcgaattaga aaacgttcct acagtttcag atagaaaagg ggaggctctc ttttatgctg
   112201 atgggcttaa tacagtagag ccagtgctaa caattgtgcc atttgttgat ttaaaaacta
   112261 agaaagagtt tttaaatgta gttagaaaca tactgccaac taatgacggt cttcctcccc
   112321 tagcgaaata gggcgattgc cggaggcaga atcgagcgga gcgctctctt ttcgctaggg
   112381 gagggagagc caaccgactg ctttgcagga ggtcagaaaa aacatcccca gtactaatag
   112441 ggggtgcaca catacatgaa atgtactcta aacccttgat acgtgagggg ttacggctta
   112501 ctagttgcac caaggggtcg caaactcttg ggagagtagg gatgagaggt gtttccatgt
   112561 atgatacgga attaaaggag aaaaatatgg tttacaatat gacagataca aacattaaaa
   112621 ttggattgct tgaccttgag atgtcacagt ttgatattcc taagaaagta gtgattttat
   112681 cagttagggt gaacaataaa tacaaagaag tcaacggcga aaacgtgaag acagatgaag
   112741 taagtaaaat tacttctgct gttcttgacg ctgacaaagt gaaagttcta actgaaatgg
   112801 gaatttctac tgatgactta aaagctatta acctagaaat tatcggaaat ctagataaga
   112861 ttgcaaaact tgctcaaaat gatgctttgt tgaatgttcc tgttgaattg attcggccta
   112921 aagttcgact agcttggaac atggctagga ataattggtc tggtgtaaaa attgtgtgtg
   112981 aggatattaa agttctagga gaataatcct atgaatacag ttagaataga ttattttgct
   113041 gtgacagtta agaatatttc gccagaaaaa gttctgacag acatcctttt gattcctctt
   113101 gaaaacttta ccttgaatga ttggggcata aataagtata agcaacatta ttcttgttca
   113161 gaaattaagg tgtattttaa tgctgatagg ctttctatgg gtgtatttat tgaattaaaa
   113221 gggcaaggtt gtcgtcaata tgaagaattt ttaaacagta acgaaaataa ttggattgct
   113281 ttgataagtc gtttatatca tcataatgcc aactttacta gactagatat tgcccacgac
   113341 atatttgacg gtagcttaga tgttcaacga atatatgact attgcaagaa aggattatgt
   113401 atctcgaaag caaaacactt tgaatatcat gagaaatcag ttctagattc tggtgagcgt
   113461 gtaggagaaa cagttgcaat aggttcacga ggtaatcagc agtggtgcat atataataaa
   113521 cgcatggagc aacttggtaa gcaagagctt gtagaagttt catcttggac tcgcgcagag
   113581 cttagatgtt ggcaggagaa ggctaatata attgcagagc agttatattt aaaacgtccc
   113641 ttatcgtcaa tatattttga ggctatcaac ggtcattatc gctttattcg tccaaatgct
   113701 atagatagta atcgttggag aagaaaaaag gttgagtggt gggtaaacta tctagggaca
   113761 gaaaatcaga cagttctgag tattacaagg gctaagacga cgttacggga gtctgaagtt
   113821 tggactgaga aacaggttgc aaaaacatta gcaaaagtct atattgcaaa gtatcaggcc
   113881 tatgatgttc aaaaggcgga agattatatt caaaacttgc tcaaagaggg actttcaaag
   113941 ctaactgata atgatgaaaa ggatatagaa caatatataa gagaacagaa tagttcccaa
   114001 ctttggggaa ccgatggaag gagtgactga catatggcag atactatatc aaataaggat
   114061 ttgatttcca tgggctatag gccatcaaca gctaatgcta ttatccatca ggcgagagaa
   114121 ttacttgtat cacgaggcta tacattttat aatcgcaaac gtttgatggt tgttccaaaa
   114181 agtgttgtga aagagttgtt gggaatggaa ttgtgaaatg gcttatatcg agtataaaca
   114241 gcgtggtaag aaaagacttt ggtccttctc tatacgagaa aggagcaaga gcctactcca
   114301 taaaagcgga tttaaaacaa aacgagaagc taaaatagaa gcggagaaag ttcttcataa
   114361 gttaaatact gggagtgtct taagctctag tatgacttta tcggagcttt ataatgaatg
   114421 gcttgattta aaaattttac ctagcaatag aagtgtagtt actaaaaaaa aatatctcat
   114481 gagaaagaag gtcatcgaaa ggttatttgg aaataagcct gtatcacaaa ttaagcctag
   114541 cgagtatcaa aaaattatga atgagtatgg agagactgta tcgagaaatt tcttaggaag
   114601 attgaattct tgtattcggg caagtataca gatggctatt gctgataagg tgataataga
   114661 ggattttact gcttatgttg agttgttctc ttctaagagt ggacaaaagg ttgaggaaaa
   114721 gtatttgcat gctgagtcag attatcaaaa agttttagta tatttgaaaa ataagtttga
   114781 ttatcaaaaa tctattgtac cgtatgtaat ttatttcctt tttaaaactg gcatgcgttt
   114841 ctccgaattg attgctctaa cttgggatga agttgacgag cttaatgagc aacttaaaac
   114901 ttatcgtcgt tacaacaccg ctattcataa gtttactcca cctaaaaaca atacttcaat
   114961 aagattagtt cctattactt cagatatgct ttccttgtta aaaacattga aaatattgca
   115021 attaaaaaca aataaagaat taaatattga taatgaaaat aatttgattt ttcagcattt
   115081 tggctatgtc tacgatgttc cagatattgc aacagtcaat aaagctataa aagtaatgtt
   115141 gaaggaattg caaatttttc cattgattac taccaaagga gctagacaca cttatggtag
   115201 ttatttatgg cataataata ttgatttggg agttatagcg aaaattttag gacataaaga
   115261 tatctccatg ttgattgacg tttatgggca taccttggag gaaaaaatta gtgaagagtt
   115321 tatggctgtg aaaagtttgt tgtaaaaaca cggcaaattg cacgacaatt tttaaaagga
   115381 aggcaaaaaa agccctatat tataaggctt ttcctgttgt atttatatgc cccctacagg
   115441 gatcgaacct gtgacccacg gattaagagt ccgctgctct gccagctgag ctaaggaggc
   115501 aaagaaaaaa gctgtattgg tgccgaaact tcacggtttg tattgaaccc gcgcaattaa
   115561 gcaggtgggc aactcgctct aactgaagct gtttccgtgt gagacggcct acatgctgtt
   115621 agaagacttt tgtttcccta ataatacaaa aaatagtcgg tcaacactta agtgtgaagt
   115681 cgtacaccac agcgtttcta tacttatatg ataccacttt ttcaaaaaaa atcaagagga
   115741 aagtgcaatt ttttgaaaag gatttcagat ttttcgcaaa cggtcgatag cttcctttct
   115801 ttgagccaaa gcccgttcat atttaccagt atcttctgct tggaaatagt gatgattacg
   115861 aattttttct ggcagatagt cttgcttgac ccaatttcca ggatagttgt gtggatagag
   115921 atagtcttgg gcattcccca gttccttgct tccactgtag tgcccatcac gtaggtgtcg
   115981 cggaataggc aagtgccctg atgttttgag gtcagcaagt gccttatcca tagctacata
   116041 ggctgagttg gattttggag aaagggccaa atcaatcacg acattggcaa tgagaatgcg
   116101 ggcttctggg aacccaatct tctgggcagc atccagagca gtcacggtat gaatctgggc
   116161 ctcaggattg gctaagccga tatcttcata ggcgataaca gtcaagcgac gagcgagact
   116221 aggcagatcc ccagcctcaa tcaagcgggc agtatagtgg agactggcat ccacatctga
   116281 gccacgaata gacttttgca gggcagatag aacatcatag tgaccgtctc catccttgtc
   116341 catagtgatg tagcttctct gaagactatt ttccatgatg tctaaggtga tgtggcgaat
   116401 gccctcgtca ttctcagggg tagagagaac agctaagtcc agtgagttaa aggcagagcg
   116461 aaggtctccg tttgtagagg ttgcgatgaa atccagcgca tcctcatcta gttctattgg
   116521 aaaatcaaaa ccacgttcag ggttacttag agctatctgc agggcctctt tgacgtcttg
   116581 gttagacaga ggttccaact cgaaaatttg aactcggcta cgaatggcag gagtgacaga
   116641 gaagaaagga ttttcagtcg ttgctccaat catgatgacc agtccacttt ccaagagagg
   116701 caagaggaag tcttgcttgg tcttatctag tcgatgaatt tcgtctagca ataggacgag
   116761 accaccagaa aatttagctt cttccgagat ttcttgcagt cgctttttac tatcaactgt
   116821 cgcattgaaa gttcgaaagg catacttggt cgttccagcg atggcagagg caatactggt
   116881 tttgccgatt ccaggagggc catatagaat catggaggac aggcggttgg cttccaccat
   116941 gcggcggatg atttttccag gtccgaccag atgctcctga ccgatgacct ggtcgatggt
   117001 tttagggcgc atgcgaagcg cgagattgtc tggcatagca gtcctttcta gcgtggattt
   117061 gagtagaatg actcatctac tatatcttac tatgtccatt ctagcctatt agttgtgata
   117121 tttcaatggt tttgtaataa tcagggagtg agatagaatc ttttttacta tttaatttaa
   117181 tgaggagagg tatcagcatg agagatttga ttttccttaa agctcaaaat aggatagttg
   117241 agcctaaaga agtggaagtg ctgacttgag aaataatatt gctgaatgtc attgtatgaa
   117301 ctataatgaa aagagaggtg ataagcaatg gaaatgatgg accaagtcag gaaattttga
   117361 tttttacaaa acaaattcgt cattggattc ttagtgatca agttatttca gggaaaagaa
   117421 aacttttctt ccgggaagat actccaaaag agattttaga tttgtacgaa aacattaaat
   117481 ctaaacttga ttttgcttac caataagttt attctaataa tgggttgaaa aaatatgaaa
   117541 aatagaataa ttgatgtttt tgaagtagta aatcgcatcc ttgtaataac tgttgaaaat
   117601 cctgatttcg aagacttgag agttaatcat actcaatgaa aatcaaagag caaactagga
   117661 aactagccgc aggctgtact tgagtacggt aaggcgacgt tgacgtggtt tgaatttgat
   117721 tttcgaagag tatcagtttg taaaaattgg agataaaaaa tatagagtac gcagtgttcc
   117781 tatgattcat tcaactccgc ctcaatctgt cttagatcga gatactttta caattgacta
   117841 tacagatgat gaattgctcg ataaagaagc agtttttact actcattaga aaaataggtc
   117901 tgaataaatt ggcttccctt agaaccacat ctaggggctt ttatgtataa tagaataata
   117961 agtatcactc ctttacaata cgtgtaacac gtgttataat ggtgttgtca ggaggtaaaa
   118021 gcgctatgcc tatgacacaa aaagagatgg ttaaactcct tacggcccat ggttggataa
   118081 agactagagg cggtaaaggc tcccatatta aaatggagaa gcaaggggaa agacttatca
   118141 caatccctca tggtgagctg aataagtaca ctgaaagagg gataagaaag caagctgggt
   118201 tgtaaaattc agcccctgtt ttttgatatg gaggtagtga aatgttagtt acgtatccag
   118261 ctttatttta ttatgacgac acagacggaa cagaagcgac ttattttgtc catttcccag
   118321 attttgaata ctcagctaca caaggagagg ggatttctga ggctttggct atggggtcgg
   118381 agtggctagg gataactgtt gcagatttga tagagagtga tggagagtta cctcagccat
   118441 cagatatcaa tagcttgtct ttaattgata atgatccttt taaagatgat gaagatttcg
   118501 tgtcaaccta tgaccttgat aaatctttta tttctatggt atctgttgat gtatcagaat
   118561 acctaggaag tcaggaaccc ataaaaaaga ctttgaccat accaaaatgg gcagataagt
   118621 tgggacgaga aatgggactt aacttttctc agactttgac agacgctatt gcagataaga
   118681 aagttcaagc ctaagattaa gcgtggtatc gtggtaatag tcaataaaaa agcacgtcca
   118741 cttgtgctag ttactcgcct attgatttta tagatttatt agccctttcg cgggcttttt
   118801 atattgattt ttatgagaaa tgaagaaatc agacttttaa gaaaatcact gataccaagg
   118861 gtttaaatga ggtaatatgg tataattagg acataaaata attttgtggt aagatggtag
   118921 tatctatttt agcatatttc cgagcaatcg gggcgattaa agagtcgcat agaaagagga
   118981 caaaatggca acatacggat ttttagatgt tttagaggaa gagttggaca agaactttcc
   119041 ctttgacttt gagattagct gggacaaacg caaccatgcg gtagaagtga gttttctatt
   119101 ggaagcgcaa aatgctgcag gtgtggagat ggtggatgaa gacggagagg ttttatcaga
   119161 tgacattctt tttgaggaag cggtcctttt ctacaatcct gccaagtcaa cagtcaatga
   119221 ggaagactat ttgactgtta ttccttacct gcctaaaaaa ggattttccc gtgaattttt
   119281 agcttatttt gcgcttttcc ttaaagatac tgctgaggtt gggctagatg tcctcatgga
   119341 ctttttggaa gacccagaag cagaggaatt tgtcatggaa tggaaccaag aagtctttga
   119401 agaaggaaaa gttggcttgg aagagggaga attttatcct tatccaagat actaggagtt
   119461 ggttggaggt gttatgaaga aaattgggac ttatttggtt tatgtgctag cttttgtctt
   119521 tattatgcta gcttttgctt gtggaacaat cgcatttgca gagttggggt attccgcagt
   119581 tttagccttt acttttggtt atgccttcgc tcttctaagc atgtatttaa tctttattct
   119641 tcatgagctg ggtcatgctt tttgtggcta cttgacaggc tatcggctgg tggcttttgg
   119701 attaggacat tttattttga ccaaaaagtc aggcaggttt catcttagta gaacagccat
   119761 tctgaaaaat gttggtgctc aatacattgg tttaaaagag gatgaaagcg atcaaagaat
   119821 catcctgatg ctttcaggag gcttgatggt tcatctcggc ttgatattat tggcgatagt
   119881 gtttggattt ttgacaagaa gctggtattt tgcagggact tggatttttc ttaatttatc
   119941 tttcttccta aataacattt tgccagtcga catcaccgat ggagcaaaaa tttgggaatt
   120001 actacaacac cctgaaaata ccaaatacgc ctacctggta ttgagacatt ctgctcaaac
   120061 tttgctggct cctcaagaat atgatttgaa agactttgtt caagcagttc ctgaggatgc
   120121 acgagggagt tttgcggatg gtgtattagg tatgcaaggt gaagtttcca ttttggaagg
   120181 gaaggaagaa gtagctaaac agcagtttca agcattactt gagaggacaa ctactccgat
   120241 gatgcagaca gttgcccaac tatccctgct tcatatcgcc ttgttggaag gagattttga
   120301 gcaagcggag caatatgcta gtattcgaca ggtcaaatcg tttctgtctc tcaaactgtc
   120361 caatcttcaa gtgatacaag cttggtatca atttaaggta aagaaagatg tagatcgaac
   120421 tcgtaaggct ctcaagattg ctagacagaa aatggatagt agtcgaatgt tgagggacga
   120481 gaaacgctat tatgaaaact tgttagcaga gctggaaaag gaaatgttag aaggaactga
   120541 agatggaact agaaatttct gatttcccag gctgtaagat tgctttgttt tgtggggata
   120601 agctcttgac tatcttacgt gatgataagg caagtattcc ctgggccaat atgtgggaac
   120661 tgccaggtgg tggacgtgaa ggtgatgaaa gtccttttga gtgtgtagcg cgtgaagttt
   120721 atgaagaact gggcattcat ctgactgaag attgtctgct ttggagtaag gtttacccaa
   120781 gtatgctttt tgcagacaaa cagtccgttt ttctagttgg tcagttgaca cagaaccagt
   120841 ttgacagtat cgtatttgga gatgaaggac agggctatca gctgatgaat gttgaggaat
   120901 ttcttagttc cagtcaagtt gtccctcagt tgcaagagag attaaaagat tatttaaaag
   120961 taagtgatta gaaaggatgg ttcagttaaa tttctaaact gaacccgccc taaacactgt
   121021 gccaaaaaga taaacttctc ttagacacaa gcgtcttcag agaatttcct attttggttt
   121081 tgtgttttac gggcttggta tcttaataat ggaaacatgg caagagttaa aagttacagt
   121141 gaagcgtgag ggagaggagt tggtttccaa tctcttgatt gagctgggag cgcaaggagt
   121201 cgcaatcgaa gacagtatgg actatgtggg aaatgttgac cgctttggcg agattttccc
   121261 agaggtggag cagcaagaag aaatcgttgt gacagcctac taccctgaca cggtggatgt
   121321 gacagtggtt gaggcggact tgcaggctcg catatcagaa ttgacggatt ttatggattt
   121381 gggagagtta aaaataggta cgactgcctt ggctgaggaa gactgggcag acaactggaa
   121441 gaaatactat gagccagctc gtatcactca tgatttgacc atcgttccct cttggacaga
   121501 ctatgaggcg actgcgggag aaaaaattat caagctggat cctggcatgg cttttggtac
   121561 tggaacccac ccaactacca agatgagcct ttttgccttg gaacaggttc ttcgtggtgg
   121621 cgaaacggtg ctagatgtgg ggactggttc aggggttctc tctattgcca gctcgcttct
   121681 gggggctaaa gaaattttcg cctatgacct ggatgatgtg gcggttcgtg tggctcagga
   121741 aaatattgag ctcaaccctg gcatggaaaa tatccatgta gcggctggag atttgcttaa
   121801 gggtgtggaa attgaggcag atgtgattgt ggctaatatc ttggcggata tcctcattca
   121861 tctaatagac gatgcctatc gtttggttaa ggacgaaggc tacctgatca tgagtggcat
   121921 tatcaaggac aagtgggaca tggtgcgcca gtcggctgag tcagctggat ttttcctcga
   121981 aactcacatg gttcaagggg aatggaatac ctgtgtcttt aagaaaacca aggatatctc
   122041 tggtgtgatt ggaggctagc atgcagcagt attttgtaaa aggcagtgct atctctcctg
   122101 tcactatcga ggacaaggaa accagtaagc atatgtttca ggttatgcgc ttgaaagaag
   122161 aggatgaggt taccttagtc tttgatgatg gcatcaagcg cttggcgcgc gtgctggata
   122221 tggaaaatcg tcagtttgag ttggtccaag aattaaatga caatgtggaa ctaccagtcc
   122281 aagtgaccat cgcatctgga tttcccaagg gagacaagct ggagttcatc gctcaaaaag
   122341 taaccgaact gggtgctagc caaatctggg cctttcctgc agactggtca gttgccaagt
   122401 gggatggcaa gaaattgggt aaaaaagttg aaaaactaga aaaaattgcc cttggagcag
   122461 ccgagcaaag caagcgtaat attgtaccaa gtattaaact tttcgagaaa aaagcagatt
   122521 ttctagctca gctggaccag tttgacttta tcatagtagc ctatgaagaa tcagctaaag
   122581 aaggagaagc cgctgcgctt ctgcaagcag tcactggtct tgaaacagga gccaaactgc
   122641 tctttatctt tggtccagaa ggcggtctct cacctgcaga aatcgaaagt tttgaagcta
   122701 agggagccgt tttggtaggc ctaggtcctc gtattttgcg agcagaaaca gcaccgcttt
   122761 acgccttatc agcccttagt gttttagtag aattagagaa ataagaggaa gaaaatggaa
   122821 caaaaacacc gttcagaatt tccagagaag gaactctggg acttaacagc cctataccaa
   122881 gaccgtgagg atttcttgcg tgcaatcgag aaagctcgtg aagacatcaa ccagtttagc
   122941 cgtgattaca agggcaatct tcacactttt gaggatttcg agaaggcctt tgcggaatta
   123001 gaacagatct acattcagat gagccatatt ggcaactatg cttttatgcc tcagacgacg
   123061 gactatagca atgacgaatt tgccaatatt gcccaagctg ggatggaatt tgaaacagat
   123121 gccagcgtag ccttgacctt ctttgacgat gccttggtgg tagcagacga ggaagtcttg
   123181 gaccgtttgg gtgaattgcc tcacttgacg gcagctattc gtcaggccaa aatcaaaaaa
   123241 gcccactatc taggggctga tgtggagaag gccttgacca atctcggtga agttttctat
   123301 agtccgcagg acatttatac taagatgcga gctggggatt ttgaaatggc tgactttgaa
   123361 gcccatggca agacctataa aaacagcttt gtcacctatg agaatttcta ccaaaatcac
   123421 gaggatgctg aggttcgtga gaaatccttc cgttccttct cagagggact tcgtaagcac
   123481 caaaatacgg ctgcagcagc ctatctggct caggtcaagt ctgaaaaact cttggctgat
   123541 atgaagggat acgactctgt atttgattat cttctagctg aacaagaagt ggaccgtgtc
   123601 atgtttgacc gccagattga cctcatcatg aaggactttg caccagtcgc tcagagatac
   123661 ctcaagcatg ttgccaaggt aaatggtctt gaaaagatga cctttgcaga ctggaaattg
   123721 gacttggaca gcgccctgaa tcctgaagtg actattgacg atgcctatga tttggtcatg
   123781 aagtcggtag aacctttggg gcaagaatat tgtcaggaag ttgctcgtta ccaagaagag
   123841 cgctgggtgg actttgctgc taacagtggc aaggattccg gtggttatgc ggcggaccca
   123901 tatcgcgtac acccttatgt actcatgagc tggacaggcc gtttgagcga tgtctatacc
   123961 ttgattcatg aaatcgggca ttctggtcaa ttcatctttt cagacaatca ccaaagctat
   124021 ttcaacgccc acatgtcgac ctattatgtt gaagcaccgt caaccttcaa tgaattgcta
   124081 ctcagtgatt acttagagaa ccagtctaat gacccacgtc aaaaacgctt cgctctggct
   124141 catcgcttga cagacaccta cttccataac tttatcaccc acctcttgga agccgccttc
   124201 cagcgtaagg tgtatacatt gattgaagaa ggggagacct ttggagcaag caaactcaac
   124261 agcattatga aggaagtttt gacagatttt tggggcgatg ccattgaaat cgacgacgat
   124321 gcagctttga cttggatgcg ccaagctcac tactatatgg gcttgtatag ttacacttac
   124381 tctgctggtc ttgtcatctc gacagctggt taccttcatc ttaaaaactc agaaactgga
   124441 gctgaagact ggctcaatct cctcaaatca ggtggtagca agacaccact tgagtcagcc
   124501 atgattatcg gtgctgatat ttcaacagac aaaccactcc gtgataccat ccaattcttg
   124561 tctgacacag ttgaccagat tatcgcctac agtgctgagt tgggggagta aggggataga
   124621 gaggttgtta tagaatgggt atggacagtt atttgcttaa aagtccatgt ttaaatcccc
   124681 cattcctttt cgaggaattc tttgccctgc tctgtaatgg taagtgaacg tggcgtttgt
   124741 gcagggatga ccaattgttt ttcactgaaa aattctaaaa gagcattgcc gagagctccg
   124801 ccgacatgat ttttacgttc gctccaatcc aaacatttag ggcaaaattt ccgttttttc
   124861 tttttcaatt catccgtatc aatgtgtaat tttttttgga aataagactt cccagcttca
   124921 gtgagttgga agtctttttc tgattcgctg aggagatttt cttgcaagag ataattggta
   124981 atggaaatgc caagctcacc agcaatatgg tcatagcagg tgcgagcgac ctttaattcc
   125041 tttttgtgaa tgtgttgttt ataacttttg acatcacgct gaggagagta gaagctgaga
   125101 aattccagca tttctgcaat ggcagcactt tttaaagaat aataatgaaa acgtccatag
   125161 gtttgtagag tggttacctg cgcttcggta agtaatttga ggtgatagct gacagtatgt
   125221 tgcttgattt tggtaaagct ggcaatttcg ttaaccgtgt gagcttttcc atccattaga
   125281 atatctaaaa tgtgcatccg agaagggtct gataagagtt ttgtgatgat gaaaatatct
   125341 ggttccataa aaattttctc caaatttcat atatcgatta ttttctatct tttattatac
   125401 tataatcaaa gcacaagaaa aatagatttt aaaaatgttt tactagagaa tattttaaat
   125461 tttattgtct gagtttaaat ggaggtaaaa ttacaaaagt aattgcagca gtatccacag
   125521 ttgaaggacg ttaatcttaa gattacattc tcaacatttt ttcaaaagtg agatgaatta
   125581 acaaagtatc caacatgctc tatttgttgg ggaaagaaag agtgaagaag ttaagtgtta
   125641 aaaatctaaa aaagcaatat ggttcttatg aagctgtcaa gggaattagc tttgaattgg
   125701 gagaaggaga gtgtttgggt atcttgggaa tcaacggtgc tggcaaaaca tccactttaa
   125761 agatgattta ctcactgacc tcaatttcct caggagagat tgatatcttg gggcaaaata
   125821 ttgaaaccaa tcgtcgtaag agtaaatctt gtctgggtat tgtagggcag gaggatatgc
   125881 tggatatgac cttgaatgtt tatgataatc tttttgctca cggtctatgt tatggtatct
   125941 catctgtcga acttaggaag agaatcgatt ttctcttgga ttttgttcaa ctgagcaaac
   126001 atgcgcaaaa gatggtgaat cagctgtcgg gtgggatgcg acgacgtctt gtcttggcaa
   126061 gagctctcat caatcggcct gatattatca ttttagatga accgacagtt ggtttagaca
   126121 ttcaatcccg caatattatt tgggataaac ttttggagtt gaaggaatta ggtgtttcca
   126181 tcattattac ttcccactat atgaatgaga ttgaatattt gacagatagg gtgctgatgc
   126241 tccaccaagg gactatcaaa gaagaaggaa ctgtagaaga cttgctcatc aagtatgatg
   126301 ctgacaacct tgagacgctt tttttggggt tgactgggac agagaaggag gacttgcatg
   126361 tttaagttat catttcactc catcggacac gttgtggtac gcaactacat gagttttaga
   126421 aatttattta aaatttcaat tgtccccaac cttatcgacc ccctctttta tcttttagca
   126481 atgggatttg gagttggtgc ttatttgacg catgttaacg gtatgctcta ccgtgatttt
   126541 gtcattacag gtttaattgc tgcgactgcc atgtctgcgg ccactgcaga aacaacggtc
   126601 aatgccttta tccagtataa gattgaaaag acttatgatg ctatgttgat gacgccaatc
   126661 aatacgaatg atattgtggt gggtcaggct atctgggcag gtattcgtgc agtgattttc
   126721 ggtgggattt tttggctgat ttccatgctt atcacagcgc attttcatgt cttgatgtta
   126781 ttgattcctc tgattttatt tatagtgggt tatttgtttg gtgttttggg actaatcttt
   126841 acctacttgg cgccgtctag ggaatttctg aattactaca atgttttggt aatccgtcct
   126901 ctttatatgt tttcagatac cttctttccc attacttcct tgcccccaat acttggtgat
   126961 ttgacttggt tttctccctt gtatcacgct acccgcatga ttcgtattat atggggaggt
   127021 gaggtgacag gtttgtatct tcatcttatc tggttgatag ccttggcgct cttgataacg
   127081 gtgcttccta tgtatatgtt acatcgtaga tattatagat agtctaatta tttgtgatgt
   127141 tgtagtcata ttctaattta tactaaacgt tattcgaatt tggacaggta tgggaactgt
   127201 gcctatcaat attgtaattt atggaagttg aaatagtacg gttcagtttt taaaatattg
   127261 ttagaaattg ttttaaattc cctaatcaat ttgtatagtt tttatttcac tttattataa
   127321 ctagtttttc gcaatttttg agacaggaat gtgatttttg tgataaggct ctatcattac
   127381 aagttcattt gtggtcatat ggaataaatc atttatatat cttttcagaa atatgctgtt
   127441 tctctgaata taaatgtctt tttcttttta acttaatttt acaaattggt aaagtcattt
   127501 aagactgcct ttttgaacag ttgctagaaa tgtagaggta ttgaccatgt atcaagattt
   127561 actaagaaaa atagcagaag aaaaaccaaa ttataaccag gaagaaatcc agtggttgtt
   127621 tgatcatttg ggaaatcctt ctccagaaat tcgtgatgac cttgttttta caagctttgc
   127681 taaggagatt caggaagagc tatttacaca ggaacaattt catttcattg ctgaggtggt
   127741 cttagctgat ggagggttag ataaagagat tgataaggta ggcttgtcaa cacttgaacg
   127801 ttcttttagg gcacttattt atgcaaatct cttgtctgca gatgctaacc agcaatcggt
   127861 tttttatcag ggattacaat cagaaattcg taatgtcctt ttaaatcaag gcttgcacta
   127921 tctttcaaaa gaaaaggata caacaggttt ctcaagtcag tatggttggg ttcattcttt
   127981 tgcacatgga gccgatttac tgacagaggt ggtctgtcat ccagactttc ctataaacag
   128041 aattcatgaa gtatttgata tacttggcca actatttaaa agaatgtcga ttctctttac
   128101 agatgatgag gattggcgtt tagcaagagt gatctatgaa cctattttac aagggaagtt
   128161 ggagcaagaa caagtagctt cttggataaa aactgttgat tttccgatag aagaaaggga
   128221 ggatttttac aaattttcca actttagatc ctgtctggtg gaagtctatg tccaacttga
   128281 ccagagaaat agtttacaag atgacctgaa agaagctatc cagtcttttc aatactaggg
   128341 attagctaat agttctatga ttttcaaaaa atttccaatc aattttcttg aaaccctttc
   128401 ctacttttga tagactagta tctagttttt gaaaaaagga gaaagaaaat gaaaaaattt
   128461 gttgctgagt taatcggtac gttcatgctt gtgttcgttg ggacaggagc tgttgttttt
   128521 ggaaatggtc ttgatggcct tggtcacctt ggaatcgcct ttgcctttgg tttggcaatc
   128581 gtggtggcag cctactcaat cggaactgtt tcaggtgctc acttgaaccc ggctgtttcg
   128641 attgctatgt ttgcaaacaa acgtttgtca tcttcagaac ttgtaaacta catccttggt
   128701 caggttgttg gagctttcat cgcttctggc gcagtcttct tcctcttggg taattcaggt
   128761 atgtcaactg ctagtcttgg tgaaaatgcc ttggcaaacg gtgtcactgt ctttggtggt
   128821 ttcttgtttg aagtcatcgc aactttcttg tttgtcttga ttatcatgac tgtgacttca
   128881 gaaagtaagg gcaatggcgc gattgctggt ttggtaatcg gtttgtcatt gatggcgatg
   128941 attcttgtcg gactgaagat tactggactt tcagtaaacc cagctcgtag cttggcacca
   129001 gctgtcttgg taggcggcgc agcccttcaa caagtttgga ttttcatcct tgcaccaatc
   129061 gctggtggag ttcttgcagc ccttgttgca aaaaatttcc ttggaacaga agaataattg
   129121 aaactcaaaa agccttgctc ctcatcttga ggaacagggc tttttcgtat gatactcttc
   129181 gaaaatctct tcaaaccacg tcagcttcac cttgccgtag gtatggttac tgacttcgtc
   129241 agtttcatct
//
LOCUS       DBERCW010000002       113603 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.002, whole genome shotgun sequence.
ACCESSION   DBERCW010000002 DBERCW010000000
VERSION     DBERCW010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 113603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 113603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..113603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.002"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(126..995)
                     /gene="thrB"
                     /locus_tag="ACL72M_000136"
     CDS             complement(126..995)
                     /gene="thrB"
                     /locus_tag="ACL72M_000136"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGS0715341.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(997..2283)
                     /locus_tag="ACL72M_000137"
     CDS             complement(997..2283)
                     /locus_tag="ACL72M_000137"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGS0715342.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQEFGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2434..3171)
                     /gene="mecA"
                     /locus_tag="ACL72M_000138"
     CDS             complement(2434..3171)
                     /gene="mecA"
                     /locus_tag="ACL72M_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGS0715343.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3371..4405)
                     /locus_tag="ACL72M_000139"
     CDS             complement(3371..4405)
                     /locus_tag="ACL72M_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS0715344.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4434..5867)
                     /locus_tag="ACL72M_000140"
     CDS             complement(4434..5867)
                     /locus_tag="ACL72M_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGS0715345.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQLWGIVLVIIFVAKMLTKEN"
     gene            complement(5883..6869)
                     /locus_tag="ACL72M_000141"
     CDS             complement(5883..6869)
                     /locus_tag="ACL72M_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0715346.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6871..7974)
                     /locus_tag="ACL72M_000142"
     CDS             complement(6871..7974)
                     /locus_tag="ACL72M_000142"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0715347.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7964..8809)
                     /locus_tag="ACL72M_000143"
     CDS             complement(7964..8809)
                     /locus_tag="ACL72M_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0715348.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9088..10362)
                     /gene="psr"
                     /locus_tag="ACL72M_000144"
     CDS             complement(9088..10362)
                     /gene="psr"
                     /locus_tag="ACL72M_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGS0715349.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10359..11207)
                     /gene="pheA"
                     /locus_tag="ACL72M_000145"
     CDS             complement(10359..11207)
                     /gene="pheA"
                     /locus_tag="ACL72M_000145"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS0715350.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11204..11680)
                     /locus_tag="ACL72M_000146"
     CDS             complement(11204..11680)
                     /locus_tag="ACL72M_000146"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGS0715351.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11673..12956)
                     /gene="aroA"
                     /locus_tag="ACL72M_000147"
     CDS             complement(11673..12956)
                     /gene="aroA"
                     /locus_tag="ACL72M_000147"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGS0715352.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13048..13386)
                     /locus_tag="ACL72M_000148"
     CDS             complement(13048..13386)
                     /locus_tag="ACL72M_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGS0715353.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13397..14500)
                     /locus_tag="ACL72M_000149"
     CDS             complement(13397..14500)
                     /locus_tag="ACL72M_000149"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGS0715354.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14510..15676)
                     /gene="aroC"
                     /locus_tag="ACL72M_000150"
     CDS             complement(14510..15676)
                     /gene="aroC"
                     /locus_tag="ACL72M_000150"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGS0715355.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15686..16753)
                     /gene="aroB"
                     /locus_tag="ACL72M_000151"
     CDS             complement(15686..16753)
                     /gene="aroB"
                     /locus_tag="ACL72M_000151"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGS0715356.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKTRGNTLKLVLVS
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16772..17626)
                     /locus_tag="ACL72M_000152"
     CDS             complement(16772..17626)
                     /locus_tag="ACL72M_000152"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGS0715357.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALENVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17616..18293)
                     /gene="aroD"
                     /locus_tag="ACL72M_000153"
     CDS             complement(17616..18293)
                     /gene="aroD"
                     /locus_tag="ACL72M_000153"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGS0715358.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18290..19453)
                     /locus_tag="ACL72M_000154"
     CDS             complement(18290..19453)
                     /locus_tag="ACL72M_000154"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGS0715359.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20138..21772)
                     /locus_tag="ACL72M_000155"
     CDS             complement(20138..21772)
                     /locus_tag="ACL72M_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715360.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21753..22502)
                     /locus_tag="ACL72M_000156"
     CDS             complement(21753..22502)
                     /locus_tag="ACL72M_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715361.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            22681..24135
                     /locus_tag="ACL72M_000157"
     CDS             22681..24135
                     /locus_tag="ACL72M_000157"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGS0715362.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24225..26843)
                     /gene="alaS"
                     /locus_tag="ACL72M_000158"
     CDS             complement(24225..26843)
                     /gene="alaS"
                     /locus_tag="ACL72M_000158"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGS0715363.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPCITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(26865..27350)
                     /locus_tag="ACL72M_000159"
     CDS             complement(26865..27350)
                     /locus_tag="ACL72M_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGS0715364.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27625..27864)
                     /locus_tag="ACL72M_000160"
     CDS             complement(27625..27864)
                     /locus_tag="ACL72M_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715365.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28125..29195)
                     /locus_tag="ACL72M_000161"
     CDS             complement(28125..29195)
                     /locus_tag="ACL72M_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0715366.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29192..29965)
                     /locus_tag="ACL72M_000162"
     CDS             complement(29192..29965)
                     /locus_tag="ACL72M_000162"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715367.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29962..30768)
                     /locus_tag="ACL72M_000163"
     CDS             complement(29962..30768)
                     /locus_tag="ACL72M_000163"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715368.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30749..31906)
                     /locus_tag="ACL72M_000164"
     CDS             complement(30749..31906)
                     /locus_tag="ACL72M_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715369.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32066..32971)
                     /gene="murB"
                     /locus_tag="ACL72M_000165"
     CDS             complement(32066..32971)
                     /gene="murB"
                     /locus_tag="ACL72M_000165"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGS0715370.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33083..33835)
                     /locus_tag="ACL72M_000166"
     CDS             complement(33083..33835)
                     /locus_tag="ACL72M_000166"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGS0715371.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33845..34576)
                     /gene="budA"
                     /locus_tag="ACL72M_000167"
     CDS             complement(33845..34576)
                     /gene="budA"
                     /locus_tag="ACL72M_000167"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGS0715372.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34718..35989
                     /locus_tag="ACL72M_000168"
     CDS             34718..35989
                     /locus_tag="ACL72M_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGS0715373.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLKELERHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36009..36824)
                     /locus_tag="ACL72M_000169"
     CDS             complement(36009..36824)
                     /locus_tag="ACL72M_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0715374.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(36981..37634)
                     /gene="phoU"
                     /locus_tag="ACL72M_000170"
     CDS             complement(36981..37634)
                     /gene="phoU"
                     /locus_tag="ACL72M_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS0715375.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37646..38404)
                     /gene="pstB"
                     /locus_tag="ACL72M_000171"
     CDS             complement(37646..38404)
                     /gene="pstB"
                     /locus_tag="ACL72M_000171"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0715376.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38417..39220)
                     /gene="pstB"
                     /locus_tag="ACL72M_000172"
     CDS             complement(38417..39220)
                     /gene="pstB"
                     /locus_tag="ACL72M_000172"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0715377.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39231..40115)
                     /gene="pstA"
                     /locus_tag="ACL72M_000173"
     CDS             complement(39231..40115)
                     /gene="pstA"
                     /locus_tag="ACL72M_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS0715378.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40105..41022)
                     /gene="pstC"
                     /locus_tag="ACL72M_000174"
     CDS             complement(40105..41022)
                     /gene="pstC"
                     /locus_tag="ACL72M_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS0715379.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGRTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41022..41900)
                     /gene="pstS"
                     /locus_tag="ACL72M_000175"
     CDS             complement(41022..41900)
                     /gene="pstS"
                     /locus_tag="ACL72M_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGS0715380.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42474..43778)
                     /locus_tag="ACL72M_000176"
     CDS             complement(42474..43778)
                     /locus_tag="ACL72M_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGS0715381.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43779..44552)
                     /locus_tag="ACL72M_000177"
     CDS             complement(43779..44552)
                     /locus_tag="ACL72M_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGS0715382.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44542..44820)
                     /locus_tag="ACL72M_000178"
     CDS             complement(44542..44820)
                     /locus_tag="ACL72M_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGS0715383.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44820..45221)
                     /locus_tag="ACL72M_000179"
     CDS             complement(44820..45221)
                     /locus_tag="ACL72M_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGS0715384.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45431..46048)
                     /locus_tag="ACL72M_000180"
     CDS             complement(45431..46048)
                     /locus_tag="ACL72M_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGS0715385.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46038..46811)
                     /locus_tag="ACL72M_000181"
     CDS             complement(46038..46811)
                     /locus_tag="ACL72M_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGS0715386.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46822..47559)
                     /locus_tag="ACL72M_000182"
     CDS             complement(46822..47559)
                     /locus_tag="ACL72M_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGS0715387.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47564..48694)
                     /gene="hemW"
                     /locus_tag="ACL72M_000183"
     CDS             complement(47564..48694)
                     /gene="hemW"
                     /locus_tag="ACL72M_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGS0715388.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48778..49167)
                     /locus_tag="ACL72M_000184"
     CDS             complement(48778..49167)
                     /locus_tag="ACL72M_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGS0715389.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49140..49566)
                     /locus_tag="ACL72M_000185"
                     /pseudo
     CDS             complement(49140..49566)
                     /locus_tag="ACL72M_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(49567..50355)
                     /gene="lgt"
                     /locus_tag="ACL72M_000186"
     CDS             complement(49567..50355)
                     /gene="lgt"
                     /locus_tag="ACL72M_000186"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGS0715390.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            complement(50348..51283)
                     /gene="hprK"
                     /locus_tag="ACL72M_000187"
     CDS             complement(50348..51283)
                     /gene="hprK"
                     /locus_tag="ACL72M_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGS0715391.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51413..51589)
                     /gene="rpsU"
                     /locus_tag="ACL72M_000188"
     CDS             complement(51413..51589)
                     /gene="rpsU"
                     /locus_tag="ACL72M_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGS0715392.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51729..52436)
                     /locus_tag="ACL72M_000189"
     CDS             complement(51729..52436)
                     /locus_tag="ACL72M_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGS0715393.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52587..53615
                     /gene="queA"
                     /locus_tag="ACL72M_000190"
     CDS             52587..53615
                     /gene="queA"
                     /locus_tag="ACL72M_000190"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGS0715394.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFY
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54276..54665)
                     /locus_tag="ACL72M_000191"
     CDS             complement(54276..54665)
                     /locus_tag="ACL72M_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS0715395.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54719..55426)
                     /locus_tag="ACL72M_000192"
     CDS             complement(54719..55426)
                     /locus_tag="ACL72M_000192"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGS0715396.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKEATDTVIKVPAKSKVEEVFVPFATKYEADNDLSAGQEQEITLGKNGKIVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEISIETEYLDGPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(56126..56677)
                     /locus_tag="ACL72M_000193"
     CDS             complement(56126..56677)
                     /locus_tag="ACL72M_000193"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0715397.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57027..57851)
                     /gene="nadE"
                     /locus_tag="ACL72M_000194"
     CDS             complement(57027..57851)
                     /gene="nadE"
                     /locus_tag="ACL72M_000194"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGS0715398.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57848..59308)
                     /locus_tag="ACL72M_000195"
     CDS             complement(57848..59308)
                     /locus_tag="ACL72M_000195"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGS0715399.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59424..59912)
                     /locus_tag="ACL72M_000196"
     CDS             complement(59424..59912)
                     /locus_tag="ACL72M_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGS0715400.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59902..60111)
                     /locus_tag="ACL72M_000197"
     CDS             complement(59902..60111)
                     /locus_tag="ACL72M_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0715401.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60497..60967)
                     /locus_tag="ACL72M_000198"
                     /pseudo
     CDS             complement(60497..60967)
                     /locus_tag="ACL72M_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(60992..61863)
                     /locus_tag="ACL72M_000199"
                     /pseudo
     CDS             complement(60992..61863)
                     /locus_tag="ACL72M_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62220..62948)
                     /locus_tag="ACL72M_000200"
                     /pseudo
     CDS             complement(62220..62948)
                     /locus_tag="ACL72M_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            complement(63208..63519)
                     /locus_tag="ACL72M_000201"
     CDS             complement(63208..63519)
                     /locus_tag="ACL72M_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGS0715402.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(63534..64820)
                     /locus_tag="ACL72M_000202"
     CDS             complement(63534..64820)
                     /locus_tag="ACL72M_000202"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGS0715403.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            65417..66001
                     /locus_tag="ACL72M_000203"
                     /pseudo
     CDS             65417..66001
                     /locus_tag="ACL72M_000203"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            65998..67188
                     /locus_tag="ACL72M_000204"
     CDS             65998..67188
                     /locus_tag="ACL72M_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGS0715404.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(67703..68695)
                     /locus_tag="ACL72M_000205"
     CDS             complement(67703..68695)
                     /locus_tag="ACL72M_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0715405.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            68855..70609
                     /locus_tag="ACL72M_000206"
     CDS             68855..70609
                     /locus_tag="ACL72M_000206"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715406.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            70593..72314
                     /locus_tag="ACL72M_000207"
     CDS             70593..72314
                     /locus_tag="ACL72M_000207"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715407.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            72325..72909
                     /locus_tag="ACL72M_000208"
     CDS             72325..72909
                     /locus_tag="ACL72M_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS0715408.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            72909..73604
                     /locus_tag="ACL72M_000209"
     CDS             72909..73604
                     /locus_tag="ACL72M_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0715409.1"
                     /translation="MSTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            73592..74956
                     /locus_tag="ACL72M_000210"
     CDS             73592..74956
                     /locus_tag="ACL72M_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715410.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSINVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(75638..76810)
                     /locus_tag="ACL72M_000211"
                     /pseudo
     CDS             complement(75638..76810)
                     /locus_tag="ACL72M_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730289.1,RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(76791..76985)
                     /locus_tag="ACL72M_000212"
     CDS             complement(76791..76985)
                     /locus_tag="ACL72M_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0715411.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLCEQVAYLTQKLSGKSSEKSVCPF
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(77155..77505)
                     /gene="tnpB"
                     /locus_tag="ACL72M_000213"
     CDS             complement(77155..77505)
                     /gene="tnpB"
                     /locus_tag="ACL72M_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0715412.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(77486..77671)
                     /locus_tag="ACL72M_000214"
                     /pseudo
     CDS             complement(77486..77671)
                     /locus_tag="ACL72M_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(77975..79537)
                     /gene="guaA"
                     /locus_tag="ACL72M_000215"
     CDS             complement(77975..79537)
                     /gene="guaA"
                     /locus_tag="ACL72M_000215"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGS0715413.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CLYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            79679..80377
                     /locus_tag="ACL72M_000216"
     CDS             79679..80377
                     /locus_tag="ACL72M_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0715414.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(80420..81316)
                     /locus_tag="ACL72M_000217"
     CDS             complement(80420..81316)
                     /locus_tag="ACL72M_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0715415.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(81325..82260)
                     /locus_tag="ACL72M_000218"
     CDS             complement(81325..82260)
                     /locus_tag="ACL72M_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGS0715416.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(82257..82982)
                     /locus_tag="ACL72M_000219"
     CDS             complement(82257..82982)
                     /locus_tag="ACL72M_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGS0715417.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(83066..83701)
                     /locus_tag="ACL72M_000220"
     CDS             complement(83066..83701)
                     /locus_tag="ACL72M_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGS0715418.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(83703..84530)
                     /locus_tag="ACL72M_000221"
     CDS             complement(83703..84530)
                     /locus_tag="ACL72M_000221"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0715419.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(84552..84887)
                     /locus_tag="ACL72M_000222"
     CDS             complement(84552..84887)
                     /locus_tag="ACL72M_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGS0715420.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(84888..85604)
                     /locus_tag="ACL72M_000223"
     CDS             complement(84888..85604)
                     /locus_tag="ACL72M_000223"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGS0715421.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRAQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            86117..86728
                     /gene="def"
                     /locus_tag="ACL72M_000224"
     CDS             86117..86728
                     /gene="def"
                     /locus_tag="ACL72M_000224"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS0715422.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            86773..87501
                     /gene="rlmB"
                     /locus_tag="ACL72M_000225"
     CDS             86773..87501
                     /gene="rlmB"
                     /locus_tag="ACL72M_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGS0715423.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(87540..88451)
                     /gene="trxB"
                     /locus_tag="ACL72M_000226"
     CDS             complement(87540..88451)
                     /gene="trxB"
                     /locus_tag="ACL72M_000226"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGS0715424.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(88517..88741)
                     /locus_tag="ACL72M_000227"
     CDS             complement(88517..88741)
                     /locus_tag="ACL72M_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGS0715425.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(88819..89562)
                     /locus_tag="ACL72M_000228"
     CDS             complement(88819..89562)
                     /locus_tag="ACL72M_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0715426.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(89562..90362)
                     /locus_tag="ACL72M_000229"
     CDS             complement(89562..90362)
                     /locus_tag="ACL72M_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0715427.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(90520..90876)
                     /locus_tag="ACL72M_000230"
     CDS             complement(90520..90876)
                     /locus_tag="ACL72M_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS0715428.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(90889..91401)
                     /locus_tag="ACL72M_000231"
     CDS             complement(90889..91401)
                     /locus_tag="ACL72M_000231"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGS0715429.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(91401..91895)
                     /locus_tag="ACL72M_000232"
     CDS             complement(91401..91895)
                     /locus_tag="ACL72M_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS0715430.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            92030..92476
                     /locus_tag="ACL72M_000233"
     CDS             92030..92476
                     /locus_tag="ACL72M_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGS0715431.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            92473..93120
                     /locus_tag="ACL72M_000234"
     CDS             92473..93120
                     /locus_tag="ACL72M_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGS0715432.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(93141..93722)
                     /gene="pdxT"
                     /locus_tag="ACL72M_000235"
     CDS             complement(93141..93722)
                     /gene="pdxT"
                     /locus_tag="ACL72M_000235"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGS0715433.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(93723..94598)
                     /gene="pdxS"
                     /locus_tag="ACL72M_000236"
     CDS             complement(93723..94598)
                     /gene="pdxS"
                     /locus_tag="ACL72M_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGS0715434.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(94750..96129)
                     /gene="nox"
                     /locus_tag="ACL72M_000237"
     CDS             complement(94750..96129)
                     /gene="nox"
                     /locus_tag="ACL72M_000237"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGS0715435.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            96423..97346
                     /locus_tag="ACL72M_000238"
     CDS             96423..97346
                     /locus_tag="ACL72M_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGS0715436.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            97406..98011
                     /locus_tag="ACL72M_000239"
     CDS             97406..98011
                     /locus_tag="ACL72M_000239"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS0715437.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            98030..99274
                     /locus_tag="ACL72M_000240"
     CDS             98030..99274
                     /locus_tag="ACL72M_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGS0715438.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSS
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(99497..99754)
                     /locus_tag="ACL72M_000241"
     CDS             complement(99497..99754)
                     /locus_tag="ACL72M_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGS0715439.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(99796..101832)
                     /gene="glyS"
                     /locus_tag="ACL72M_000242"
     CDS             complement(99796..101832)
                     /gene="glyS"
                     /locus_tag="ACL72M_000242"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGS0715440.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(102092..103009)
                     /gene="glyQ"
                     /locus_tag="ACL72M_000243"
     CDS             complement(102092..103009)
                     /gene="glyQ"
                     /locus_tag="ACL72M_000243"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGS0715441.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(103028..103789)
                     /locus_tag="ACL72M_000244"
     CDS             complement(103028..103789)
                     /locus_tag="ACL72M_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS0715442.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(104062..104904)
                     /locus_tag="ACL72M_000245"
     CDS             complement(104062..104904)
                     /locus_tag="ACL72M_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGS0715443.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLESLKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(105019..106410)
                     /gene="pgdA"
                     /locus_tag="ACL72M_000246"
     CDS             complement(105019..106410)
                     /gene="pgdA"
                     /locus_tag="ACL72M_000246"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGS0715444.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(106648..107016)
                     /locus_tag="ACL72M_000247"
                     /pseudo
     CDS             complement(106648..107016)
                     /locus_tag="ACL72M_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            107237..108214
                     /locus_tag="ACL72M_000248"
     CDS             107237..108214
                     /locus_tag="ACL72M_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS0715445.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            108211..109293
                     /locus_tag="ACL72M_000249"
     CDS             108211..109293
                     /locus_tag="ACL72M_000249"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0715446.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTINLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(109357..110387)
                     /locus_tag="ACL72M_000250"
                     /pseudo
     CDS             complement(109357..110387)
                     /locus_tag="ACL72M_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            110830..112155
                     /locus_tag="ACL72M_000251"
                     /pseudo
     CDS             110830..112155
                     /locus_tag="ACL72M_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(112264..113460)
                     /gene="tuf"
                     /locus_tag="ACL72M_000252"
     CDS             complement(112264..113460)
                     /gene="tuf"
                     /locus_tag="ACL72M_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS0715447.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
BASE COUNT        34567 a        24516 c        20575 g        33945 t
ORIGIN      
        1 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa
       61 cttcttttca caaaaaggat atgaaaccct ctggttaaga gtttccccat cctatcttct
      121 attctttatt ttgcttctac acggacacct tgggtatcaa ctctcaagtc atgcagtttt
      181 cctttgaaag gttgcttttc caattctgcc ttaattgttg gcatcttgtc atgagaagcc
      241 agaaccataa ctgtcggccc agcaccagaa aggtaggttg cataggcccc attttctttg
      301 gtcacttgct taatcatcgc aaattctctt accaagtcct gacgataacg ctcatggaag
      361 aggtctccct cgattgcttg cccagcggtc accatgtctc ctgccaacaa ggcagcaacc
      421 gctacattgg cgatagaact tgcagcaaca gcttccttat aagacaattt tttaggcaag
      481 acactacggc tgtcgcgagt acgtaattca tagtttggaa tgtaagctag aaaatcacac
      541 tctggaaagt ctgctacgat agcagagact tgcccttcaa cagaacttgc aataacgaga
      601 ttaccataaa tggctggagc cacattgtca ggatgccctt caatcttggt cgctaactgc
      661 aatttttcat ggtctgataa gttgagttga cccagttggt tggctagttc aatcccagca
      721 acgataaccg agctggaaga acccaaaccg cgcgccaaag ggacatcact ggtcattttc
      781 aagcgtcttg gttgcaagtc tggtacaatt tgcaaagcga ttttgagcaa gagattacgc
      841 tcatcatgtg gaatccattt gccaatctgg tgttcaatca gccactcatc tcgttcttcg
      901 cagacctcaa tttgaagata cttggttaca gctacaccga ccgagtcaaa acctggcccg
      961 atattggcac tggttgcagg tacaataatc ttcatcttat tctcctagca ccttgaaggt
     1021 attcaagagg tcgaattctg aaaccttctt caattcagct gagacatttt caagctgggc
     1081 tttattaatc ttgtgtgtga tgataacgac acgcgccttg tcaccctctt tgccatcttg
     1141 aaggatttgc ttaaaggaaa tatcttgagc attgaagatt tcagccaact tcaagacctg
     1201 accttttgag tctggagcca agattgagaa atagtagttt gctttgacat cttcaggatt
     1261 tgccaagacc aagtcacggc tatattcgtt gaagtctttg ccaatggtac catcattcaa
     1321 acgacgaacg atacggacaa tatcagctac aacacttgtt gcagttggtt tttgacccgc
     1381 acctggtccg tagtacatag actcaccaat accgatagat tctacaaaga cagcgttcat
     1441 tacgccattc acactagcaa gtgggtgcgc tttaggtagg aaggttggag tcacttctgc
     1501 agcaatacct gaagaagttt cctcaataga accaaccaat ttcactacgt aaccaaactc
     1561 ttgagctaca gctacgtctt ctggtgtgat attgcggatt cccttgtggg ctacatcatc
     1621 aaaggcaatc ttcatgccaa aggcaaattg gctcaaaata accatcttgt aggctgcatc
     1681 aatcccatct acgtcattcg tcggatcgct ttctgcaaat cctagacgtt gtgcttccgc
     1741 aagagcatca tcgtaagacc agccttcttc caccatcttg gtcaccatga agttggaagt
     1801 tccgttgact actccaagca cgcgcgtaat tttatcagaa gccaaggaat ttgctaaagt
     1861 acgaagaatt ggaatcccac cagcaactgc tgcttcgtag taaagtgcta ccttgttagc
     1921 ttgagcgatt tctagcaatt ctgcgccatg gacagctaaa aggtccttgt tagcagtaac
     1981 aacgtgtttt ccagcttcca aggcacgagt gataaaggtt ttagcaggct caatacgccc
     2041 catcaattcc actacgatag taatatcctg gtctgataaa atatcatcca cattggttac
     2101 aaagttaaag tcattccctg ctgcaagcaa gcgatttttt tcatcttcat ccttgaccaa
     2161 taccttagca actttgatat ctgaatgtgc tgattgattg atttttcctc cattttcctt
     2221 taggaggaaa ggcacaccac ttgcaacggt accaaatcct agtaaagcaa ttttaactgt
     2281 catctttatc tcctcgaaat tttctaatat agccattata acagaatttt gtgaaaattc
     2341 ctattatagt aaatcactat ttcagtataa aaagaaaaaa cgaatcagac gattcgctct
     2401 tcttaaaatc tgaaaatagc tttccagaaa ggattagccg attttttgca gattgagcac
     2461 tgcatcgtga ctcatcaaga cttgaccata ctcttgtaag actgagcgac tgatatcact
     2521 atcgtctgca aactcgcgca tacgggccaa cagccaagct ggatatgggc ttggatgatt
     2581 ttcaatatcc actaaaatgg tcaaataata gcgctcgttc attttgtaga gttcagaagt
     2641 ttccatttca aaagtcactg tcttggcaaa aactaccaag tcagccaact tagcaaaaga
     2701 aaggatgtag tagatgtaag gttctttctt actctcagct tcttgttcag cctgctcttg
     2761 ctcttcttcc ttggcttcaa cttgctcaag agattgaatg gcttcgatat catccttggt
     2821 tttgtctgcg atgctttttt ccagggtttt gataaattca tctggagaca tttgagccaa
     2881 ttcttccata tctggcaaat ccgataagtc ttcaaaatct agattttggt caatctttga
     2941 cttggtcaca aagacatcta ccttatcagg ttttggagtc acacggaagc tcaacatgcc
     3001 tgtatccaga aagctatcag gcatctctag ttcatccaag atagcataaa agaactcttc
     3061 tgttttttct tgaggaacga gaaagtcagc aatctccatt ccacgatcca tcaaatcctc
     3121 taaagacatc gtgattttta aagttgtatc actaatttgt ttcattttca ttgctagtaa
     3181 cctcatactt tcagttctat ctattatact agatttttac gattttatca aaagaaggct
     3241 cctctatacg gatagatttt ccctagggtc tttctatagg agactccaaa agaaaatttc
     3301 tgcagacaga tagaaaaagc cttcaaaatc agctcttagc cgattttgaa gaccttatac
     3361 atcagaatac ttataattta aaggttgcta caccaaggat agaacgattt aagtttctga
     3421 gaatttgaag actttgctca aatttcttat aacgagtcac tccgtactct tcaacaagaa
     3481 ggactgtatc tctttccaaa agagatgata catcctgtaa atctacaaaa tgcattcctt
     3541 ttaaagcttc ttgactctgt ttcaatttat ctaggatagc tttatttgag ctaacgatgg
     3601 tcaattcctg tccagtattt ttgtatgaca aaacatctgc taggttagca attgttgtaa
     3661 tctctgttac aaaatcaatt tgatactgag aaaaatcacc tactctattg attgttggat
     3721 taaagagata aactaacaca tttcccatca caaccaaaat cacacaaacc actccaataa
     3781 caactaaacg aagaatcaga tttttcacat ttaagccaag cgctgtttca ccatttgcgt
     3841 tcaattcttt agagttgatg gtttccagtt tttcaatttt cacatttgca taggcatgtt
     3901 taaatttctc aatcaaccca tcaatttttt tctctaacaa gtcattggca tctttacttg
     3961 atgtcaaaat tttcacacca acccctgcat cgtcaatcat atagtagacg gtcaattttt
     4021 tccaccaata gtcattcgtt gaatttttca aggttgtttc tgtcgtgtct aattcactgg
     4081 caattttttt caactcactg ggttctacat cattgaaaag ataagctcca ttcaaattac
     4141 catcaatcaa tttcccataa aaatcactat aaccaccaat ttgatgattc aaaatcgttt
     4201 tggccgactc ttttggagga gtgattttat agataagata agttgaataa cttgttgtat
     4261 ctttgacagt gtttttattc ctaactgctt taattgtaaa tggtacagca atgagagcaa
     4321 ataaagcgat gagagctaaa atatttgctt ttcgcttttt ataaagattt gcaaacaaat
     4381 cagctactga ataatgttca aacatgattt ttttctcctt tgtttagtag atactagttt
     4441 tcctttgtaa gcatttttgc tacaaatata atcacaagaa caattcccca taattgcatt
     4501 gtaaataaat tgaagaaact ttctgaaaag ctgcttcttg gcataaagaa tagattattc
     4561 aagatgagta gggataaagc aaataggatt gtccttgagc gataggctac ttgcagcatg
     4621 gctataaata atacgccgag taagaaacta agcagaaaga ctccaatcat accatagtcg
     4681 gtatacaact ccatgatata actacttccg ataccatgcc ctttcaagta ttccttgttc
     4741 aagacaagat aggatagatt gtgggcataa ctattactat caatagctag ttccacacta
     4801 ttggttgtat gttcaaaggc ttttcctccg aaaatggctc ccaaactccc ccttgcaaaa
     4861 taatcaagaa caggaccaaa agtaaaatta cggaaatctc ggtaagggag gctactgtta
     4921 aatagaaaac ctcgagccag aacaccaaaa ctagtccctt gtttatagat aaagtcaagt
     4981 aagatatccc agaaacctgt atgagaaact tggacattat cccgtacata attgagtact
     5041 cccatcgcta acatgagaat aggagaacct acaaaaatcg ctaacttttc tttaaaccca
     5101 atccattttc ctttttcagt ttgctcccgc ataaagtaat aaacaaaagc aaataaaata
     5161 cttaaaataa agggatttcg tgtcccaatt gccaaatgaa tagtattagc tgcaataaag
     5221 gagacaagca ctgctgtggc ctgcaatttc tttggcttgg ttgccagata catacacatt
     5281 gcatagaccg taaaggtaga caaaatgtag gtaaaataag gcagtttact ttcaaaattt
     5341 gcatagtagg catagtagga agtctgcaaa cgatacaaga gccgttcaaa taaccgaatg
     5401 aaatagaaag gataggttag aagaaaaact cctagtgata caaagcgtaa ccgcttgata
     5461 taaacctctt ttagagaatt tcctatattt gctactttta ttttcttcct agctatgaag
     5521 taacgagcca gaatgcctcc tgtggtcaag cccagaatcg aaaccatgac aactataaag
     5581 gcaaaacgat aggctattgg atgataggta tccaaagcac catccctaaa ataatcaatg
     5641 gtcggtcttg ataccagaaa tacaaaaatg gttaaataga aaataaaatg gattaagtaa
     5701 tacttgatat cattccaaca agcaattaag ctactaacca acaagaacaa taaagtagaa
     5761 agtaagctaa cattattatt attaaacaga tacacaattc cacttactag cgtcaaggca
     5821 taactgacta tggtcaaact aaataataat cgtttcccat caatcacttg gtcacccccg
     5881 ttctaatgta attttttaga tttttcaata tttttcagta ataagaatcg atataaggaa
     5941 atatttatga atagggccaa agcactaatt cttctcccct tacggaaaat tggattccta
     6001 gaaatagcaa aggcatggcc ttttaaaaaa cgatgaatct gagaataggc ttcaaactgt
     6061 ttatactgat catctagcaa catcttatcc agaataaaga agtgggcata ggccaatctg
     6121 aaaaaagcga cctctttcaa gtcaggatag tttttcacaa cttcattata aaacttttgg
     6181 tagatatcaa tataggctaa atccttctct gcatagggtt tggtcgtaat actatcccct
     6241 ctatggaaat agtaataata gggtttagta ttaaccacat acttcttggc caacttgatt
     6301 aaatcaaaat ggtaataggc atcttcgtaa atcaacccct taggaaagga tagggcagtt
     6361 gcaatctgtc tcttgattag cttattgcaa atcgtcccag gtattttttc acctatgagg
     6421 tattccttta gaaatgtttg agaatcacag acaaaatagt catcctgatt ggctgactgt
     6481 gggctttcat cattagcata gacattcatg acaccacagc ttgaaacatc cgcatcttct
     6541 tgaactaatt gctcatataa gctctgaatc atttctggat ggatataatc atctgagtca
     6601 ataaaaatca gataatcccc gtgagcctgc ttcatcccat catttcgtgc ttgcgacaat
     6661 ccttcgttct ttttatgaag cactgacacc ctgtcatctt gttcagcgat tgaatcacac
     6721 aagcgaccac tttcatctgt tgcaccatca tcaacaagaa taatttccag attttgatag
     6781 gtctgcttct gaatggaagc tatcgatttt tctaggtact gcgccacatt atagactggc
     6841 acaatcacac taattaatgc agtttccatg ctactcctct aatagttttt ctacttgttc
     6901 gatttgtttt gtaattgtaa attgttgaat gaattggcta gcctcatcga catcaaagtt
     6961 tgaggcagaa gtcatgtaat tagtaatcgc ctgagctgcc tcttgattgc tctcaatgat
     7021 ttgtccaaat cgtccttctt gggataattc ctcagcccct ccaacgttcg tagagataaa
     7081 agggagtccc agactcaagg cctccacata cactccagga aaaccttctt gtttagacat
     7141 agacaaaaga actttcgtct gagatagata ctgataagga tttttttgat aaccaaggaa
     7201 atgtacatag tcctcaatcc catactcttt gactcgtttt ttcagttcct cttccatatc
     7261 accagccccg ataaaataga gatgatagtt ttttccctct tggtgtaata atcgtatcac
     7321 ttccactaca cggtcagaac ccttattttc ctcaatccgt ccgatagtac agatactttg
     7381 aggagcaatc tcgatatcga tcttctcttg agatttttct agaatagtct gaaaatcata
     7441 tccattgtag attgtctgta atttagaagt ataatctgga taaacttcct tgatagaatt
     7501 gctggtcttt tttgaaatcc ctacaattgt attcgcagca tccaactggc ttctatgtga
     7561 ttctctttta gagctatcct taagaagttc ttcaatactt ccatgaatcc aagatatctt
     7621 cttgacttct cttcttttag agaacaacag tggtggattc ataatggtaa aagaaacttc
     7681 aacatcataa tcatctttta caagcaaacg acgagccagt cttggaaaat aaattctcat
     7741 tctccacaaa aaagctcgta accatctggt ttggcgataa tcttgaaggg attttaaaat
     7801 gcgtacatgc tttggaacag attcatatcc cttgtcaaag tgctccattt caagaatatc
     7861 aatatcatac ttttctggat ccagatttga aacaatggtt gatagaatct tctctgcacc
     7921 acctccaaga gaaaaagacc acataaaaaa taagattttt ttcttagcca ccatattctc
     7981 ccttgtattc tgtataagac ttatccatat cagcgatgac agcatcatga tgcggtacct
     8041 gcttgtctgc tggtggaggc gtcatataat ccccaaaagc agttctgaga tagacatcat
     8101 agccgattgg aataggcatc tctgttcctt caaatggcaa gaaaagattg tcttcaaaag
     8161 atgtgattgg gtacttgttt ctcatgtagc caggacctga gcataattct gtaatgccat
     8221 cacaatcagc caaatcatac ttagtcattt ctttctcagc ttttttccag atgcgataac
     8281 agagagattt tggagtcaaa cccagtaaaa tgcgacttcc ccatttcatg agagcaccat
     8341 gcttttctgg aatagtttgc gcacaaaaga gtgaataaat caaggcccaa cgaacctgtt
     8401 ttttccgctc agctggattt ttcggataat aatccaaagg caaaacatcc aaggccagac
     8461 catgtggcaa atccaaatcc tgctgataag gcttgataca ggtggtttcc ttgtcacgaa
     8521 tggtaataaa aagattacga tcaacaaaat ccttgtgact ctttgacaag aaataacgtt
     8581 catctgcata acgaggccat aattctgcta atttctcata atctttacga ggcataaaaa
     8641 agtctaggtc gtcgtcccaa ggaataaatc ccttgtttcg aagggcacca atagcgcctc
     8701 cgccacagag ataacagagc aaatcatgtt ctttacaaaa ggccacaaaa tattcagcca
     8761 tctccagact acgagcctga attgctttta aatcagtcat attgttcatt attctttcta
     8821 tcgtatcgtt tcattatacc acaaacaagg ggtgaaaatc tattgcagac tgtaaaaaat
     8881 caaagcctga ctgctatcca aatagctatc aaactttgat ttttctgtct tatactcttc
     8941 gaaaatctct tcaaaccacg tcagcttcac cttgccgtag gtataggtaa ctgacttcgt
     9001 cagtcttatc tacaacctca aaactgtgtt tttagcagcc tgcggctagc ttcctagttt
     9061 gcactttgat tttcattgag tattatctta tctcaagccc atttgagcga gcttggtttg
     9121 atatttgttt tgatcaacca gcaagcccaa gcctccataa acatcatagg catctaccca
     9181 gtcacccagt tctggaatcg tcaatttttc aataccattt tttgctccat ccaaaacaga
     9241 taaaccgttt gttaggagga aagtataggg tacgttggtt gaggtcatag caaaaacctt
     9301 tccaagagct tcagaaccag tgaaaagttt agtgggatct ttaatttgct ctaaaattgc
     9361 tgttaaaact tgttgctgtc tttttgtacg gccgtaatcc gcctcatcat catcacggaa
     9421 acgagcataa ttgagcaggg tcgagccatt catctgctgt tttccgactt taatggtttg
     9481 ggttggagac tcagtctcgg tagcgtataa atcatctccg actgtagctt ctgttagggg
     9541 acgcccattc aatgttgaaa attgagcatc aatcgtcacc ccatcaggga aaagcgtgtc
     9601 aatcgctgtg gcaaaggcct ggaaatcaac caaggcgtag tacttaatgt ccaagtcaaa
     9661 attatctttc aagacttggc gaaccatttc tgcccctttt tgcccctctt gttctcctaa
     9721 ctcgtaggct acgtttaact tgttatctgt ctgttttcta ccgttaatca cttgactata
     9781 accatctata tagaccaaat tatcacgcat gaaactgact agcttcattt tcttatctga
     9841 gcccccgaca tttaatacca taatagagtc agttcgtgtc tcaacactgt tctggccgat
     9901 tcgaccatca gtacccatga ttaaaatatt aactccatct ctagtgtcct gaccattaaa
     9961 gacttctact tgagctgccc gggcatcagc agttttcttt gcgctagcat cttggtaacc
    10021 acgcaaaaac atgaatacca tggccaaagc cacacagacc aaaagtgaaa aaatcaccat
    10081 aaaaattcgt ttaagacgga gcttccgtct tttctttttt ggagggaaag agagtgcttg
    10141 tgatttggat tgtgagcgac tccggttcgc atagcttggt aagtcaacct gctcttctct
    10201 ttcttgttcc aagctagagc tactatttcc cctagcaaga gttagctttt cttgcaaata
    10261 ggcaaactca tttttttctc tctcattgag atagtgaata ttttttagca aataatcata
    10321 acgcaactgc tcatgatgac ttaagggatt ttctttactc atcttctctc ctttccatgg
    10381 tctgatattg gataaatagg ataggcaccc agaattttat actggattcc aatcgcttct
    10441 aattcttttt gggcaaagtg gaccaagtcc ttatcggtat aatccacatc gataatgaaa
    10501 aagtattcac ccagtgctgt cttgagtgga cgactttcaa tttttgtcaa gtcaattcct
    10561 cgccaagcaa aggtcgacag ggccttataa agtgcacctg gaaggttgtc aggtaatgtc
    10621 aaggccaaac tcatcttttc agtttgtgct tgcaagggaa tactaggctt ttcagctcct
    10681 agaacccaga aacgtgtgaa attggcttcc atttcctgaa tatcctcggc aatcagttcc
    10741 aatccatatt cttcagcaga acttctaggt gcaactgctg caaagggctg gtctggatgt
    10801 tcggaaataa aacgggccgc ataagctgta ctagctgtta cctcgatttg agcctctgga
    10861 tattgttcat cgatgaattt ctttccttga gccaaggcct gtggatgtga aaaaatcttt
    10921 tcaatcttag tatggcctgg aaccaccatc aactgctgat gaataggctg aacgatttct
    10981 gctactgctt ggatgtgagc ctgatgaaaa agatagtcca aggtttcatg aacactaccc
    11041 tcaatagaat tttcaactgg caccacagaa tagtccacta atccttgctc ataagccttg
    11101 atgacatctg taatgttagc aaaagcctgc aattcctcat gaggaaaagc tatctgcaca
    11161 acgtggtgtg aaaatgatcc cttgggacct agataagcaa ttttcatctt agttcctcta
    11221 taatttcctc tgggcttagc ttggtcacat ccaaaacccg actagccact tcctcatacc
    11281 aagcctgtct ttcttgaaaa atagctacta gttcttcctt gctattattt agaaaaagcg
    11341 gtcgctgatt gtccttatca gctgcgatac gttggtagag ggtttcaaaa tctgctttca
    11401 ggtagatgtt atctgtatta gtcttgagta agtcacgatt tctctgagaa ataaccactc
    11461 ctcctccagt tgacacgact tggtctgttt gtagtaaatc agctaggact tctgattcta
    11521 cctgacgaaa ggctgcttct cccttttcag cgaaaaaatt cgcaatggac atacctaggc
    11581 gcttctcaat cagagcatcc atatcaaggt aattagggtc caagcctctt gcaatagtcg
    11641 attttccagc ccccataaac cctaataaca ccttagccat gaatcaagct ctccaaatca
    11701 tcaaagaaac taggatagct ggtattgatg gcttctgcac ggtcaagctc cacctctcca
    11761 tctgcaacca agagggctgc gatagctgtc atcatgccga tacggtggtc accaaacgta
    11821 ttgactctag caccgtgaag agctgatttc cctttgataa tcatcccatc tgccgtagga
    11881 gtaatatctg ctcccatact atttaaggcg tctgccacaa cctgaatacg gtctgtttcc
    11941 ttgaccttga gctcctcagc atccttgata actgttacac cttgggcttg agtcgcaagc
    12001 agggcaataa tgggcaattc atcaatcaat cgtggaatca aagcgccacc aatctctgtt
    12061 cctttcaagt cagaagactc aacagtcaag gtagaagatt tagcgactgg atcgatttca
    12121 gttatttcca attttccacc catggcacga atgacatcaa taataccggt gcgagtttcg
    12181 ttgatcccca cattctgcag cactagacga gaatttggaa caatcaaacc tgcgactaac
    12241 caaaaggctg cactggaaat atctcctggt acgaccacct tctgtcctgt caatttttgt
    12301 ggcccttgga ctgtgatttt cttaccgtcc acacttaaat gaccaccaaa ttgtttcaac
    12361 atatcttcag tatgattacg ggtgcactct ttttcgataa taactgactc ccccttagct
    12421 tgtaaggctg caaacatcaa ggctgacttg acttgggcag aggcaattgg caactcataa
    12481 tgaataggtc ttaggttttt cgtccctttt aagcgaaggg gaggcaagtc tcgttcagtt
    12541 tgccctgaaa tgctgacgcc catttttttc agtggaaggg tcacacggtc cataggacgt
    12601 ttggaaagac tatcatctcc aaacatctct acttcgaaat ctgcaccagc aaggacacct
    12661 gaaatcaggc gaatcgaggt gccagaattt cccatattaa gggcattttg tggcgctttt
    12721 aagccagcca tgcctacacc ttgaatggta ataaccccat ctttatcctc aatttcaaca
    12781 ccaaggtcac gaaaaacctg catggtcgaa agaacgtctt cacctcgcag aatatcataa
    12841 accttggtct caccctcagc caaacttcca aagataatgg aacggtggct gatagacttg
    12901 tcacctggga cgcggatact accatgtaaa tggcgaatgt ttgtttttag tttcatactg
    12961 gacctcatac ttgcaatact tttacctatt ttatcataaa aagccagaaa ttccttaaaa
    13021 attcctgact ttaggatcgt tcttttctta tttcagcaat tctgaaactg gttcaaaaac
    13081 aattttttca atgtcagaaa ggtaaatggc caattgttgt tgcttggtaa agaattctga
    13141 caagaggcta tttccttgaa tctgtttacc aaagccttcc atcttagctt ggaaggacgc
    13201 atctggcatt tgacctgtat gtgctagttt ttgaatttcc tcttgaaagg caagatattc
    13261 tgtaaagatt ttgcttgcct cagcatctgc tgcaatcgca tctttagctg ctttaacagc
    13321 cttgtattct ggtaatccgc gtagaccgcg actgagttcg tttgcactat cgtaaatatt
    13381 tgacatgttc ttctccttat ttgatgacga ctgtatagtc ggtattttct gttatgagat
    13441 gctcagctct ttccaagtct tgagcatttt taaatgaaat ttgtaggatt ccgtgaatat
    13501 cctcacgatt ttcctcgttg atgtggatgt taaccaagga agtcccacgt agcagttcca
    13561 aaatccgcag gatgacatct tcttcatcag gaacgtcaac atagaggtcg taagagctat
    13621 ccacaccacc acgcttatgg atttccatgg tctggcgttg ttcacgcgct tggttaaaaa
    13681 agttccaaat ttgctcttca tctcccttac taatggcctg accaatcact tccaaacgtt
    13741 ccttgaaatc ctcaattcta tccagaatgg tctcgctatt ggacaagaga atggaggtcc
    13801 acattcctgg ctcgctttcc gcaattcggg tcatatctcg aaaaccacct gccgcaaagc
    13861 gccttgccat ctcatgctct tgagcataga ccgcagtctg ctccatgaga ctagaagcca
    13921 aaatatgagg aaaatggcta atctgagaag tgacacgatc atgctccttg gcatcaatct
    13981 cgataaaacg agcatgaaga cctgaaagca gatccttcat ttccttaagc gtgtcctgac
    14041 ttgtcaggct tgaaggtgta aagatataat aggcattttc aaaaagattg acatctgccg
    14101 aagcagcccc tgtcttgtga ctaccagcca tgggatgggc cccgacaaag cgaacagact
    14161 tgccagccaa atactgctcc gccgcatcca caatggttga cttggtcgaa ccagcatctg
    14221 aaataataac gccttctcgc aaatccaaat tggccaactc cttaatgaaa gcaatagttt
    14281 gtttgattgg caagctgagg ataatgacat ctgccaaagg agcaaaacta gcaaaatcat
    14341 ccgttgcacg gtcaatcatg ccttctttca aggcgatatc tctcgaagct tgactacgat
    14401 tataacctaa aatttcataa tctggatgat cgcgtttgat accaagtgcc atagaggctc
    14461 caatcaaccc aagacctgcg atatagattg tttttgccat aggaactcct taatagttct
    14521 ttgtatagtc tcggtgtttg gctaccgctt cttttagttc ctcaagatta tctgatgaga
    14581 atttttcgag gatttcttgc gccagaaccg ttgctacaac tgcttccatg accattcctg
    14641 cagctggaag agcagtcgga tcacttctct ccacggttgc cttgtaaggt tcgtgggttt
    14701 cgatatccac actcataaga ggtttataaa gagtaggaat gggtttcatg accccacgaa
    14761 caacgatggg ttgcccatta gtcataccac cttcaaaacc acctagatta ttggtacggc
    14821 gagtataacc gtcttcttta gaccagagaa tttcatccat aacttggctg cctttacgat
    14881 aaccagcctc aaagccaaga ccaaattcca cccctttaaa ggcattgata gagacaacag
    14941 cttgagccaa tcttgcatcc aattttctat cccattggac ataggaacca agaccaactg
    15001 gaacgcctcc gacgactgtc tccacaaccc caccgatggt atcaccatca cgtttgattt
    15061 ggtcaatata gtccttgatt tcctgttctc gttcttggtt aacaatagaa acttcagact
    15121 gggcagctct ttgcttaatt tcagcgactg tcagattttc aggaacatcg atttccttgc
    15181 caccaaagac cacgacatgg ttggcaatct ccatatccag ctcagccaag aggcgtttgg
    15241 ctactgcacc aactgccacc cgcatggtgg tttcacgagc tgatgaacgc tccaaagaat
    15301 ttcgcaaatc atcaaaacgg tacttaatcc ccccaaccaa atcggcatga cctgggcgag
    15361 gatgagtaat tttccgcttg cttttaaggc ggtcttcaat gtcctccgca gacatgatgt
    15421 ccagccattt ctggtggtcc ttattgatga catccatagt aataggcgcc cctgtcgtct
    15481 tcccgtggcg aacgcccgaa gtaaagacaa cctggtcact ctcaatcttc atacgaccac
    15541 cacgaccgta gccaccctga cggcgtctaa ggtcctcatt gatatcctca gctgtcaatg
    15601 gaagtccagc tggaattccc tcaataatag ctgttagacg ggggccgtgt gattctcctg
    15661 cagttaaata tctcatacac tctccttatt ttaccaagta gtctttcatc tcttccagag
    15721 aaactgggtg aatgatcgct gaaccaagct ctgacaccaa gaccaatttc aaggtgttac
    15781 cacgcgtttt cttgtcatga gtaagagcct gataaagctt gtcaacttcc caattttcat
    15841 agtcaacagg caagccgaat ttctgacaca tctctgtgat agattgggta atgccagctg
    15901 gcatgaggcc tttttcctca gcaaccttgg aaatctgtac cattcccatg gcaacagcct
    15961 ctccatgcat gaccttgcca taaccggcag tcgcttcgat ggcatggcca atagtgtggc
    16021 caaaattgag gtaaagacga ataccattgt ccaactcatc ttcaaccacc atcttgcgct
    16081 tcacctgaca agaatgttca atcaaggtct ctgcatgttc caaaatgctc tcaacagaac
    16141 cattcagttc cgtcaagaga gcccacagtt ctggatcctc aatcaagcca tacttgataa
    16201 cttcacccat cccttcaatc aactctcttt ttccgagggt ttcaagaaca agtggatcaa
    16261 tcagaacccc atctggttgg gcaaaggtcc ccaccatatt tttagcaaat ggtgtgttaa
    16321 cgcctgtctt tccaccgata gaagaatcaa cctgagctgt caaactagtc ggaatctgaa
    16381 caaagtgaat accccgcata taggtagagg ctacaaatcc agccaggtcc ccaacaacgc
    16441 caccaccaag agcaacgatt ccatcgctac gagtcagacc ttgcttgact agaaattcat
    16501 agactttctg aacagtagtt aaattctttc tttcttcacc ttctaagaaa tcaaaaacag
    16561 ctacctgaaa accagcatct tctaggctga gcttgacctt ctctgcatag agagaggcta
    16621 catggttatc tgtcacaatg actacctttt gcggttgcca gagttctcgc aaccactgac
    16681 cagcctgggc catacaacct ttttcaatct gaatatcata aggatgatga ggaatatcga
    16741 ttctgatttt cataggagag tctccctttc tttattggta tttttctgtt aaagactgcc
    16801 aaatctcttc tgtcggcatt tccttgcctg tccacagttg aaaagcttct gcagcttgat
    16861 agagcaacat tcccagacca ttgactgctg gattgccctg acttctagcc catttcaaaa
    16921 acggtgtttc aaagggttgg tatatgatat ctgcaactaa gagagtttct ggtaagacta
    16981 tgttttcagg aacaggagag gattggccat ccatgcccac actggtggca ttaactagca
    17041 aatccgactc ggcaatcctt gcttgcagtt cagaaacatt ctctaaagca cacaaatcca
    17101 ctttaaaacc tgtctgctcc tgtaacttgt ctaggtaagg tcttgttttt tccatagaaa
    17161 cggaacgaac aaagaccgaa atctgactga cgccatccaa aatagcctgt gccaagattg
    17221 atttagccgc accacctgca cccagcaggg tcatcttttt acctgaaatt gtaaaagaag
    17281 gcaagcactt aaaaaatccc ttgccatctg tattatatcc aattaaattg ccattctcat
    17341 tgacaaccgt attaaccgca ccaatcaagc gcgcttcatc gctcagctta tccaaataag
    17401 gaatcacctg ctccttatag ggcatggaca gattgatgcc aaacatctgg tagcgacgaa
    17461 tattggccac tgtttctgcc aagtcactcg cttcaatctc ccaagccaca taagcaccgt
    17521 tggtagctgt cgcctcaaag gctctattgt ggatgaaggg agaaatagaa tgcttaatag
    17581 gattggcaac aactgcagct aaacgtgtat agccatcaag cttcatccaa aatctccctg
    17641 atttttttca tgctagctag agaaatctgc ccaggggcac taacctcatc cagactggca
    17701 aaagaccaac tcgaaccagt cacatccgca gtgatacgag agaccttgcc caccttaccc
    17761 atagaaatgg tcacatattc ctgttcagga ttgagggttt taaagcctcg tgtatagttc
    17821 atcaagtcta agacatcctg ctccgtgtga gccatcaccg caaccttaac aagttttgga
    17881 tttaggatcg tcaactctga caagatttcc atcatgttct caggtgtttc ttggaaatta
    17941 tggtaactca aaacaagatt tgggaagtcc agcatttcct caaaaacatc cttgtagcta
    18001 tagtactcaa aatcaatata gtctggttga tagaattgcg caacttcctt gattagatgg
    18061 atatactctt ctggagaaag gtcgatttct ccaccttcgg agcgagttcg tagcgtgaaa
    18121 accaactcac ggcctgcgaa tttttcaaaa atggctggag ctacctgcaa aatcgcttct
    18181 ttaggcagat agtcggcacg ccattcaatg atgtcggcat ccaggtacct cgtggcatcc
    18241 agagcctgag cctcctctaa acttcttggc attactgaaa cgattaattt catttactaa
    18301 ccttcatact aatcaccttg aggtaattac tactttcatc ttttttatta taggcaaaat
    18361 ctgctggaag accatatttg tttaaaatct ggtaacttct tcctgcaaag cctttatcaa
    18421 tttgttctgt aaatttctga cgggaaacat tggcagcatt ggtactggca atgataatcc
    18481 ctcccggatt taaaatctca agactctggg aaatcaactt gtgataatcc ttggccacag
    18541 agaaagtttg ttttttattc cgagcaaagc taggcggatc taggacaatc acatcgtagg
    18601 tcaagtcttt gcgtttggca tatttgaaat actcaaagac atccatgact ataaaacgat
    18661 gctcgtctgt gctgagccca tttgcctgaa aatgcgcttg agacaattct cgtgaacgtt
    18721 tggctagatc aacagaagtt gtctggctag ctcctcccat ggccgcagct actgaaaaag
    18781 ccgctgtgta ggaaaacata ttgagcaagg atttacccat agccaagccg tcaactaaac
    18841 taccgcgaac ctcatgctgg tctaggaaaa ttcctgtcat caagccatca ttcataaaga
    18901 cttgatacag gacaccattt tctaaaacag tgaaaaagtc aggtgcttct tgaccataaa
    18961 catgggcaga ttcatagtca aaacccttaa agcggatttt ctcataagcc cctaaaacct
    19021 cagggaaaac ctgtctaaag gcttctgata tagtctgacg aatctgataa acataagagt
    19081 tataccaaga aaagacggcg tagtcgccat aaaggtccac tgtcagaccc ccaaagccat
    19141 ctccctcttg attaaagaga cgaaaggcag ttgtcaaatc atcttgatag taggcgtttc
    19201 tcttttcttt ggcttttcta aacaacgttt caaagaaagt ttgattgaag gccaccttgt
    19261 ctttgctgac aaaccagccc aagcccttgt tttgctgaga aaggtaggca gtcccaagaa
    19321 agtttccttc ctgaccctgc acctctactt cctgatcctt aagattgaca ttctcaagat
    19381 cactggcttc tagtaaaact agccccttag caagcttctt ttcaaccctt ttgctgactc
    19441 ttattctatt cataactacc attatatcaa acttttagac aattctcaaa aaagaaacta
    19501 cccttgcttt tttactcttc ttttaaaaaa tggtatacta gacttcctgc aaaactagga
    19561 aataaatgtg taagaatcac aataaaaaat gctcttccgt cttggaggag catttctttt
    19621 tatcaacgaa aatcaaatag caaactatga aactagcctc aggttaaccg tgagattata
    19681 ggtagagagg ttgtatcagc aatatgtgtc tgtcaaattt agtgacaaag gtagtagaag
    19741 aaagatgaag aaataaatca gcttcagtag gtatctggaa aatttgattt tatagagaag
    19801 ccttttgtta caaactcaat atactatcaa taaataatat tatagaagca acaataatta
    19861 aaatttcacc tatttgcatc attctatttc gaactctaaa tatatgttct atcaaaaata
    19921 cttggatcac acacattata ggaattaacg tttttgaaat tgaaaaatat cccaataaat
    19981 aaactataaa caacaataat agaactatat tatatttctt attcaaaaca ttcctcccta
    20041 tatttttgat taccaatctt aatcatttac aactacattc taacaaacta taaaagcgtt
    20101 tgtcgaattg aatttatcaa gcaagcaacc aactatctca tcttttttct atttctgcca
    20161 atatgcgtga caggtaataa tgatagccaa aaatagcaag agcaagcaag acgataagag
    20221 ctcctactcc caagttgatg gcaaggatag gggagagaga ctgaaccaag aatatgctcc
    20281 caattacaag ggccatcagg attgcactat aaataaacaa taaaactatg gcgactatgc
    20341 catttgaacg attcaccagg tccgtaatgc tactccaatt ggttgacaga tttttaacgt
    20401 ccttaaagta atggtggcaa gaaaggatga cactggcaat gatccagact acaagaaggt
    20461 aaatcatcga aaggatggac aagcctagat atagagaaag accgagcaaa gtcagaactg
    20521 gtaaaaagga ctgaacagca aagataatcc aaaatttcac tttcacataa cgagcaaagt
    20581 caaagggtaa actcttcaga aaatcaacat tttccctctc caaggacaag gcaattgaat
    20641 gcaggctggt gatattgtta ttgacaactg ctataaacac tcctacaaaa aacaagggta
    20701 accagtatgg aggatgaatg tctggaacta tctgagaatc tcggattttg gaaatcagac
    20761 tgatcatcat gagataagga aggaaagcac ttgtaaaaag cactgtaatc acaccagtcc
    20821 cctgtcccaa gagggtgagg tggtagcgta aaaccatacg gaaaaagccc tttttagtag
    20881 ttgaaatcct ctccttgctg cgacgttctt ttttgacctt ctcctcactg ttaagcagga
    20941 tcacgtcata aaaacgagga aggaccttct ttttggtcag ataaagcagg aagagagtta
    21001 gtcctatcca agcgagcaga cccactaagg cttctgtcga aaaaggctcc actgctattt
    21061 tgtaaaagat atgaagagga taaaggagaa atggaatgtc tctaactttg tcaacaatac
    21121 ttccaaaagt cgactgaaga aagaagataa atattaaagg tatgagaact cctatcccaa
    21181 tcatcacatt cgaaaaaata gactgatact ttctgaagac cctagtctga gccaagaaat
    21241 gtactgccac taccgtcact aaagtaacag agacaaataa taaggtcaag gacagtagca
    21301 tcaaaggcaa acccagccaa agagaaggag ctagactaat atagagggct agaaaataag
    21361 ctaggattgg tacaattcca gttagagctg gcaagaggac agacagacct ttggccatta
    21421 taatctctga ttctttaaag gcatagggcc tataggaggc caggtcctta ctctcataaa
    21481 agacattgta aaaggcagtg aaagaagttg aaaaggccag caccagtaaa atagcaacca
    21541 tcgagctaaa ataaataggc atttcctcaa aaggaaaatg aatggctata ttactaaaac
    21601 agatgagcat caagagactg gaaaaaatgt aagaacttag gactctagca gaaacattta
    21661 cttttttccc aggattctta gcctgcttct ttcgtagatt agccagatta gcttcttgag
    21721 atgaatagag gatattgata tcaactaatt ttttaatgac cttgagacgc atccgcaacc
    21781 tcctcttttc taccagcaag actaaggtag atactttcca aaaactggtc tgggtggtct
    21841 ttcctcaagt cctctacctt accacaataa atcaaatgcc cctttttcaa aatggcaatc
    21901 cgatcacaga cttgctctgc cacctctagg acatgagttg aaaacaagac tgtcttccct
    21961 ttttgtgcat gttccttcat catctgtttc aaatcaaagg cagcctgggg atccaaacca
    22021 gtcaagggtt catccaagac ccaaatatcg ggatcagaca agagtgctcc gatgacaaag
    22081 actttctgac gcattccgtg agaaagagtt tcaataacct gatagcgatt ttcagcaaaa
    22141 tcaaaaacgt tcaatagcct agctagacta gcctccaagt cagatctact cagatcatag
    22201 gatgaggcga tcaattccca aaattcattg gccgttaagc gtaaaaataa gtcaggcgag
    22261 tctgctacgt agccaatctt tcgtttaata gccaagcgat tttccgataa ctcctgaccg
    22321 tctaccaaaa tacgaccact gctgggtgaa atgatactga ctagggattt tatggtggtc
    22381 gattttccag ccccattatg accaatcaag cccataatct ctccattttc aatctgcaaa
    22441 ttgagattac tcaaggcctc tttatcacca tacaacttac taacattttg aaattcaatc
    22501 atgggacaac tcctatcttt atctgtatta tacatcgcta tactagcact ttgatacaaa
    22561 aaaatcaata ctttatttta agtagttaaa atagtttcct tctatcttac gcaaacgttt
    22621 gcaccaagag atactttatg atagaataaa gaacaagatt gacaagtaag aggaaacatc
    22681 atgcaaaatc aaacactcat gcaatacttt gaatggtatc tgccccacga cggtcaacac
    22741 tggacgcgtc tggctgaaaa tgctccacac ctagctcatc tggggatcag tcacgtctgg
    22801 atgccaccag ccttcaaggc aaccaacgaa aaagatgtcg gctatggggt ctatgactta
    22861 tttgacttag gagagttcaa ccaaaaaggg actgtccgca ccaagtatgg tttcaaagaa
    22921 gactatcttc aagccattca agcccttaaa gcacagggaa ttcaacctat ggccgatgta
    22981 gttctcaacc acaaggctgc tgccgatcac agggaagcct ttcaggtcat cgaagttgat
    23041 cctgtagacc gtacagttga acttggagaa cccttcacca tcaatggctg gactagtttt
    23101 accttcgatg gtcgccaaga tacctataat ggcttccact ggcattggta ccacttcacc
    23161 ggtacagact acgatgccaa acgcagtaaa tctgggattt atctgatcca aggggacaac
    23221 aagggctggg ctaacgagga attggtcgat aacgaaaacg gaaactacga ctacctcatg
    23281 tatgccgacc tagactttaa acatcctgaa gtcatccaaa acatctatga ctgggctgat
    23341 tggttcatgg aaacgactgg tgtagctggt ttccgtttgg atgccgttaa gcatattgac
    23401 tctttcttta tgcgcaactt catccgcgat atgaaggaaa aatacggtga cgatttctat
    23461 gtttttggtg aattttggaa cccagacaag gaagccaatc tggactatct cgaaaaaacg
    23521 gaagaacact ttgaccttgt cgatgttcgt ctccaccaga atctctttga agccagtcaa
    23581 gctggcgcaa actatgacct tcgtggcatt ttcacagata gcctggttga actcaagcct
    23641 gacaaggctg tgacttttgt cgacaaccac gatacccaac gaggacaagc ccttgagtct
    23701 accgttgaag aatggttcaa gccagcagcc tatgccctca ttttgttacg ccaagacggc
    23761 cttccatgtg tcttttacgg agactactat gggatttcag ggcagtatgc tcaacaagat
    23821 ttcaaagaaa tccttgaccg cctcctagcc atccgaaaag atttggccta tggagaacaa
    23881 aatgactact ttgaccatgc taactgtatc ggttgggtac gttcaggtgc tgaaaatcaa
    23941 tccccaatcg cagtccttat ctcaaatgac caagaaaaca gcaagtcaat gtttgtcggt
    24001 caagaatgga ctaatcaaac ctttgtagat ttacttggta accaccaagg tcaagttaca
    24061 attgatgagg aaggttatgg acaattccct gtctcagcta gatccgtaag tgtctgggca
    24121 gtcaatacca tctaatagct cataataacc aagctaggtc caagcggatt tggctttttt
    24181 gtattcacaa aaagacctac ccaaatggat agatctttac ttgattacaa tttacctgct
    24241 actgcatcca acaattcttg gatcttagct tggttgcttc ctcctgccat ggccatgtct
    24301 ggtttaccac caccacgtcc atcgatgatt ggtgctaatt ctttgacaag gtttcctgca
    24361 tgaaggtctt ttgtcttgct tgctacaagg acattgactt tgtcaccgat agcagcaact
    24421 aggacaagaa gatcagagta gtctttttgt ttccagttat ctgcaaaggt acgaagggca
    24481 ccggcatctg atacagacac ttgactagca atgtagcggt gaccgttgac ttccttcaca
    24541 tccttgaaga tatcgcctgc ggctgcagct gcggcttttt ctttcaactc agcattttct
    24601 ttttgaagtt gacgaagttg ttcttgaagt ccttctacct tgtgaggtac ttccttgact
    24661 tgaggtgctt tcaaggttgc tgcaacagct ttaagagcgt cctcttgttc acgataggct
    24721 tcaaaggctt ccttaccagt cactgccaag atacgacgag ttcctgaacc gattccttct
    24781 tctttgacaa ttttgaagag accaatctca gaagtgttgc caacgtgggt accaccacaa
    24841 agttcaatag agtagtcacc gatagtcacg acacgaactt ccttgccgta tttctcacca
    24901 aagagggcca tcgctcccat ttctttagca gtgtcaatat ccgtttcaac tgtcttaact
    24961 tcaagagctt cccagatttt ttcgttgact tgctgttcaa tcgcacgaag ttcctcagca
    25021 gttactgctt ggaagtgggt aaagtcaaag cgaaggaatt caacttcgtt aagagatcct
    25081 gcctgtgttg cgtggtttcc aaggatattg tgaagggcag cgtgaagcaa atgagtcgca
    25141 gtgtggtttt tcatgacacg gtgacggcga ttgctatcaa ttgccaaggt atattcttgg
    25201 ttcaaggcaa gcggtgcaag gacttcaact gtatgaaggg cttgaccatt tggggctttc
    25261 tgaacattgg tcacagtagc cacaacctta cctgactcat ccaagatttg tccgtagtca
    25321 gctacctgtc cacccatttc agcataaaat gacgtttccg caaagataag agaggcagtt
    25381 ccttctgaaa cagcttctac ttctgcattg tccgccacga tagctaccaa tttagaagac
    25441 aattggctag cattgtagtt gaagacactt tctacagtga tgttttgaag agtttcattt
    25501 tgcataccca ttgagccacc cttgacagct gaggcacgcg cgcgttcttg ctgttctttc
    25561 atggctgctt caaaaccttc acggtctaca gtcataccag cttcttcagc gatttcttca
    25621 gtcaattcaa ctgggaaccc ataagtatca tagagtttga agacatctga accagcgata
    25681 acagattgac ctttttcttt caagtctgct acaatgcctt gggcaaagtg ttgacctgag
    25741 tgaagggtac gggcaaatga ttcttcttcg ctcttaacga ttttctcaat aaagtcacgt
    25801 ttctcaagca cttctgggta gtagctttcc atgatttttc caacagttgg aaccaatttg
    25861 taaaggaaag gctcgttgat acccaatttt tgaccatgca tagaagcacg acggagaaga
    25921 cgacgaagaa cataaccacg accttcattt cctggaaggg caccatcacc gatagcaaat
    25981 gaaagagaac gaatgtggtc tgcgataacc ttgaagctca tgttgtcgcc atcttggtca
    26041 taaaccttac cagacaattt ctcgacttca cggataatcg gcatgaagag gtccgtttca
    26101 aagttggtct tagccccttg gataacggcc accaaacgct ccaaaccagc gcccgtatca
    26161 atgttcttat gtggcaattc cttgtattcg ctacgaggaa cagcagggtc tgcgttaaat
    26221 tgtgacaaaa cgatgttcca gatttcaata taacggtcgt tttcaatatc ttctgcaagc
    26281 aggcgaagac cgatattttc tgggtcaaag gcttccccac ggtcaaagaa gatttctgta
    26341 tctggtccag aaggtcccgc accgatttcc cagaagttgt cctcaattgg aatcaagtga
    26401 cttggatcca ctcccacttc aatccagcgg ttgtaagaat ctttatcgtc tggatagtag
    26461 gtcatgtaaa gtttttcagc agggaaatca aaccattcag ggcttgtcaa aagctcataa
    26521 gcccaagtga tagcttcgtc acggaagtaa tccccgatag agaagttccc cagcatttca
    26581 aacatggtat ggtgacgcgc ggtcttccct acgttttcga tgtcgttggt acggatagcc
    26641 ttttgggcat tggtaataca tggattttca gggataatgg tcccgtcaaa gtatttctta
    26701 agggttgcta ccccagagtt gatccacaaa agagttgggt catttacagg aaccaaactt
    26761 actgatggtt ctactgagtg acctttggtc gcccagaaat caagccacat ttggcgtact
    26821 tgtgcactag atagttgttt catattgtct ccttattcac ttgtttaatg tgattggctt
    26881 tccagcattt ccacatagtc aatcgcgaca cagagggaaa tgactaggtc tgcataagcg
    26941 tcttcaagaa ccgttacggt ataggtagag gtcagatgga agagttcctt cttaatttcc
    27001 gcaatcaact gatcgcgatc atccagcaat ttgaaattca aatcccagat attgccctcg
    27061 atacgaagac ctagattatc aaactcatac ttatctcgcc agaaggtcaa cttcttacga
    27121 atgacaaaac tcgagccatc ccgaagctga atctcaaaac gaggaagcaa ggtcaagatt
    27181 tctttactaa tctcactgac ttgttcacca gccgcatcat agatggtaaa ggttttagga
    27241 atcttaaaaa atgatccctc cacctgatag gcaatttctc ccctgtcatt cttgatagcg
    27301 aagcgttcgc ctccaagacg aaacttttgt ttgacaagaa atgttttcat caacacctcc
    27361 aaaaatcaaa agacaagctc atatcacgaa gggcgaaaaa ccgcggtacc accttcattc
    27421 aatgaacttg tcattctctt gttcttatgc aattgtatga ttgagtagca tgacttccta
    27481 gcttagatgg ctcgcagcac cgccatttct ctggactaag acaagtgaaa atcaattctc
    27541 aactttctta ttatatcgtt tttttaatct tgcgtcaact ggaaatgatc tccgttgaat
    27601 tagaccaatt ccctacatct ctgattactt tttcaggata tattttttct tactgccatt
    27661 tttcttttta tcccaaattt tcatattact aaacacagct actagaatat ttccaaatat
    27721 aaaggtgcct atcacccaat atatggactc agttgttagg tattgtcgat ccaagccatc
    27781 ctttaaatgg aatagtataa cagtttggtt aacaatcata aaggttggcc agaaactttt
    27841 tttgaaaaaa gtagacattt tcattatttg ttgccgcttt ctgtaaggtt aatactcaat
    27901 aaaaatcaaa aagcaaacta ggaagctagc ctcaagctgt acttgagtac ggcaaggcaa
    27961 cgctgacgtg gtttgaagag tataggctta gtatactact aggcaagcaa ataagcaaat
    28021 aaacaaataa acaactagaa tagaaaaaga tagggctcta aaaactgact tctattcctt
    28081 aaaaacgaac cagcttgact gattcgtctt cttacgttta tctcctactt ccgatacatt
    28141 ttaaactgta ggaagaggtc gctatatttc cctgtccatt tatggtcaaa tttctcataa
    28201 acttctaggt gtttcatggt ttcaacatcg ggatagaagg ccttatcttc ctttgtttcc
    28261 tctgggagca attccttcgc tggtaggttt ggtgttgaat agccgacata ctccgcattt
    28321 tggagagcat tttcaggttt caacataaag ttgataaagg cataggctga gttttggttt
    28381 ttaactgttt tgggaatgac catattgtca aaccaaagat tgctggcctc tgtcggtacc
    28441 acataacgta gattttcatt tttttctaac atttggctgg cttcaccaga gaaggtcacg
    28501 ccgattgcaa cattattctg aatcatatag cccttcatct cgtccgcaac gatagccttg
    28561 atatttggag tcagtttgta gagcttatcc actgtctctt ccaactgctg cagatccttg
    28621 gagttgaggc tgtagccgag ggaattgagt cctagtccca gcacctcacg cgccccatca
    28681 aagagcatga tagaattctt atactccggc ttccaaaggt catcccaatg ctcaggcgct
    28741 tcatctacca tggtttcgtt gtagacaatt cctaaggttc cccagaagta agggatggag
    28801 aatttattac ctgggtcaaa ggactggttg agaaactctg gtccgatatt ttcgattcct
    28861 ttaatttttg aataatcaag cggaaccaag aggtcttcgt ccttcatctt gttaatcatg
    28921 tattcacttg gaatggcaat atcgtaggtc gttccaccct gctttatctt agtgtacatg
    28981 gcttcgttgg agtcaaaagt ctcgtactga acttgaattc ctgtttcttc tgtaaactga
    29041 gtcaagagtt caggatcgat atagtctccc cagttataga taaccaattt ttgactatct
    29101 cgactattga ttttactatc taaatgagtc gcaattcccc acaagacaag gataatcgct
    29161 gcaattcctg ctaaaaatga atagattttt ttcatgcttg ctcctccttc tcacgagaga
    29221 taaagtaata acctacaact aggataatac taaagagaaa gactagagca gacagggcat
    29281 tgatttctaa ggaaatcccc ttgcgagcac gagagtaaat ctcgactgat agggttgaaa
    29341 agccatttcc tgttacaaag aaggtcacgg caaaatcatc cagcgaatag gtgaaggcca
    29401 tgaagtaacc tgcaatgata gacggagtca ggtaaggaag catgatttcc ttaaacatct
    29461 gaaattgact agctcccaag tcataggccg catgaatcat gtcgccattc atttccttga
    29521 gtcgaggcaa gaccatcaag accacgatag gaatggagaa ggccacgtga ctagatagaa
    29581 cggtcaaaaa gccaagtgaa aacttgagtt gggtaaagag aatcaagaag ctagcaccaa
    29641 tcataacgtc aggcgcaacc atgaggatat tattgagtga tagaaaggct tcttggtatt
    29701 tcttacgaga ctggtagatg taaatggcac caaaagtccc gataatggtc gctatcaagg
    29761 ctgataggaa ggccaagaaa aatgtctgag ccaaaatcag catgagtctc ccatctccaa
    29821 acatggtttc aaagtgagtc cagctaaaac ctgtaaagct attcatatca tcaccagcat
    29881 taaaggcata gccaatcaag taaaaaatcg gcaggtagag gaccagaaag accagtccca
    29941 gataaaggtt ggcaaatttt ttcatcgttc tctcctttcc ttggtcaccc acatggtgat
    30001 gaacatggtc aggatgagaa tcacaccgat ggttgaaccc ataccatagt tgtcattggt
    30061 tagaaaattc tgctcaatag ccgtccccaa ggtgataacg cggttcccac caatcaaacg
    30121 ggtcagcatg aagagactca aacttgggat aaagaccgac tgaaccccac ttcgcacacc
    30181 gttcatagat agagggaaga tgacatgacg gaaggtctcc cacttagttg caccaaggtc
    30241 gtaactagca ttgatgagat tattatccat atcgtctaag acattgaaaa tcggcaaaat
    30301 cataaagggg agctcgatgt agcttgcgac aaagataaag gaaaaatcgg taaaaagcaa
    30361 ctgttgtgaa ccaattccga taaattccaa gaattggtta atagagccat tttgaccaaa
    30421 aatcccgata aaagcatagg ctttaaggag caaattgatc caggtaggaa ggataatcag
    30481 catgagccag agttgacggt gcttgagacg ggtcaaaaag agggctgttg gatagctgat
    30541 aagcaaggtc acaaaggtca caatccctgc ataaagcact gagttgaaac tcattttgag
    30601 gtaggtcaag ttttgtgacg caaagtaaga tttataattt tctaaactaa actggccttc
    30661 aatgttgaaa aaggattgtc cgaaaatcaa gaccaagggt gccaatacaa agagggcaat
    30721 ccaaagcatg tagggcacta caaagagttt agagcttgtt ttcttcatct ctttcctcct
    30781 cgatcgcatt gatcagacct gcttcttgct cttcgatttc cacgtattct tcgatacgag
    30841 catcgaactc ttcttcggtt tcattgagac gcatgatgtg gatgtcttct gattcaaagt
    30901 ccagaccgat ttcctcaccc acgatggcct tacgggttga gtggatcatc cattcatttc
    30961 caagttcgtc ataggcgata atttcataat gaactccacg gaagagctgg gtgtcgacct
    31021 taacttggag tttgccttct tcaggaaggg taatgcgcaa gtcctctgga cgaataacga
    31081 cctcaacagg ttcatttggc ttcatcccac catcaaccgc ttcaaagcgt ttgccgttaa
    31141 attcgaccaa gtagtcctca atcatggtac ctggcaagat gtttgactcc ccgataaagg
    31201 tggcaacaaa gtggttgatt ggctcatcgt agatgtccac aggggttcca gactggacaa
    31261 tctcgccatc attcataacg aaaatccagt cactcatggc aagagcttct tcctgatcgt
    31321 gagtgacaaa gacaaaggta atgcccaatc gttgttgtaa ttcacgcaat tcgtactgca
    31381 tgtctgttct caatttcaag tccagcgctg ataaaggctc gtccaacaag accacacggg
    31441 gttggttgat gatagcacgg gcgatggcca cacgctgacg ttgtcctcca gaaagtttgc
    31501 ggatggaacg tttttcataa ccttccaact gaaccatctt gagaacttcc gctacacgct
    31561 gctcgatttc tttcttatca attttacgca agcgaagtgg aaaggcaaca ttttcaaaca
    31621 cattcatatg tgggaacaag gcataggatt ggaagacggt atgtacgtcg cgcttgttgg
    31681 ttggaatatc attgatacga acaccgtcta gcatgatatc tcctgtcgtc gcatccagta
    31741 aacctgcaat aatgtttagg atagttgatt tccccgaacc agatgcacct agaagggtgt
    31801 agaatttccc ttcttccaac tcaaagttga tgtctttgag aaccttggtg ttgctgtctt
    31861 caaaaacttt agagacgttt ttgaattcga taattggttt tttcaattgg cataaattcc
    31921 ttctttttca tagattaacc gatcggggct ctgtcaggtc cccactacct cttgcaggga
    31981 gtaaaaccac ctgcatacat cttcgctacc gataggcttt cacccccttt ccatgacata
    32041 gcagcagctt ttcaaataca gcttcctact tgctttcacc caagatccgg acttctcttt
    32101 caagcgtaat acctgagtgt tccttgactt tttcgataac cgattggatc aagtcctcgt
    32161 agtctttggc cgttccatct gcgacattga tcataaatcc tgcatgcttt tctgacactt
    32221 ctacgccacc gatacgatag cctttcaagc cagcttctga aattaactga cctgcaaaat
    32281 gcccgactgg acgcttaaag accgagccac aagatgggta ttccaaaggt tgcttgagtt
    32341 cacgtaggtg cgtcaagcgg tccatttcct gcttgataac ctgatgggtt cctggggcta
    32401 gggcaaattt aactgacaag acaactgcac cagactcctg aatagctgaa tggcggtaac
    32461 caaaagccaa gtctttagca gacagggttt cgatttctcc atccttggtc aagaccttac
    32521 aagactgcaa gatgtgagca atctcgccac cataggcacc cgcattcata aagacagcac
    32581 cgccaacgct tcctggaata ccacaagcaa actcaaagcc agtcaaacta tgacggaggg
    32641 caatgcgagt tgtttcaatc aagttagccc cagcttctgc ttcaatggta tagccatcaa
    32701 cagaaacgtt attgagcttg tcacacaaga tgacaaatcc acgaatccca ccatcacgaa
    32761 cgatgatatt gcttgcattg ccaagaacca tccaagggat attttcttgg ttggcaaatt
    32821 tcacaaggcg cgccaactca aaacgatttc gtggaaagac caaataatca gcctctccac
    32881 ctacttttgt ataactatag ctatgcaagg gttccttaaa acggatatca attccttcta
    32941 agatttcaag cattttttct cttacagaca tgtcactctt ccttttacaa aattcattcc
    33001 attataccat ttttagagac atttgacgac cataaaaata ccttgtttgg attttgcata
    33061 agaaaaagag gttcccccct ttttatgatt ttttacaaaa gatttccttg gttccatagg
    33121 cgaccagaac gagctccagt gctagaatca cttcaaccaa gactggattt gtcaaccagc
    33181 ctacttggaa aagagatggt gccagatcaa agaaggcatg caagccatag gctgctagga
    33241 gataaatcca tttcttctgg cgaacagctt ggtaaaccca aactgtcaaa agtaattgga
    33301 aaccaagcgc caagattcgc tcaaaaccaa gcaaataaat ctgccagacc gaaagtgact
    33361 gaatggtttt taacatattt tcagacagta attgcataac ctgtggattc tgagtttgaa
    33421 ctgccgaaag aacgatgtaa agattgagta aactaataag gcctagaaaa atcaactcca
    33481 agccaccatg ccctaggcca taggccaagg catctgcctt ttccaaactt ctctttttct
    33541 ccaaccattt gaagaaaaca agacgagccg tttcctcaaa aaatgctgcc atggctaggc
    33601 catagataat atagataagc ggatgatctt gcaagagggc aatactaccg tctttttgag
    33661 ggtgcaaaat caagatatgc accagttttt ccaaaatctg cgaagagaca aagaaagcga
    33721 ctgcacccaa gcccaagaca gctagattaa tctggtattt ctttttggca aaccaaatgc
    33781 ttcctatcag aaaagctagc aacagcaaca tggtaataat gatatgaatg gtcattttct
    33841 tctcctattc tgccttttca atatcttttt tcatctcgtc aacattgaac ttagcaaaca
    33901 agtattgacg gtcttggact gggaaacgtt ggtccaactg gtcaactgct cccacctcga
    33961 taatgccttc cttgatgaca aaatccatga catgtccacc gaaggtcaaa tcatctgata
    34021 tgaagtgcag atggtagcct gccacactga ccccatggaa aatctcaggc gtccagaaac
    34081 caacaatagt ccccgcaaca ttgtcacgac tatattccgg ttgatgggtt gcgacatcag
    34141 caaacttagt atcgggtgtt gacttaggaa tcatacgcac atgcatatgt gaaaattctc
    34201 cccgaatctt gatagaacgg aaaagatttt ccccatcata ataagactca attcgttctt
    34261 tcaattcctt gtctgtcatc tcaaagcgct ggcggaaaat gacctctgcc tgatgcggta
    34321 ccactgcagc gtaaggaata agggcatctg gtgacacttc cacaatttct ggctggtctc
    34381 ctgacccttt ggcctgataa gccttgccat ccaagacaat caattcccca tcaatagaat
    34441 ccaaggttcc caaaccaagg tcaccatgct ctagcaattc tcccactgtc atggtaccac
    34501 cataaaggcc agccatcaag gctccaagag tattgtattg aaataatttc actggttcct
    34561 gcacgttctt atccattcac tttcttgtct gttattctat aaatcttact cctaagtata
    34621 ccacatttgc ccctagatgt gaacgagaga aacgctctag acattgccaa gaaggaaaaa
    34681 aaagggtaca atgtaacaaa atcaagggag gtctggaatg aagaaacaaa gcaagtacaa
    34741 agaggtcgtt tcctatctga aaaatggtat cgagtctgga cgatttccga cgggtagtcg
    34801 cctgccttct atccgtcaac tgagccttga ctttcactgt agcaaggaca ccattcaacg
    34861 agccctgctg gaattacggc acgaacaata cctctatgcc aagccccaga gtggctacta
    34921 tgtcctagaa caagggcaac accaggacct agaaatcgag gttaccgacg aacatgccag
    34981 tgcctatgac gatttccgac tctgtgtcaa tgaaaccttg attggccgag aaaactacct
    35041 cttcaactac tatgataatc aagaaggatt agaagaccta agacaatcca ttcacaaact
    35101 cctctttgag caagctctct actgcaaggc taaccaacta gtactgactt ctggaaccca
    35161 acaagccttg tttatcctct ctcaaatatc ctttcctagc caagccaagg aaatcttggt
    35221 ggaacagcca acctaccatc ggatgaatcg cctcttgatt gcacaggggc tggactatca
    35281 aacgattgaa cgaggcattg atgggattga cctgaaggag ctggagcgac acttcaagac
    35341 aggaaaaatt aagtttttct acaccattcc ccgatttcac tatcctctgg gacattccta
    35401 ttctgagcaa gacaaacgat ccattcttaa cttagctgcc aagtatgatg tctatatcgt
    35461 agaagacgat tatctgggtg atttggactc caagaagggc caaaccttcc actatcttga
    35521 tacagaggag catgtcattt atatcaagtc cttctcgacc agcctttttc ctgcccttcg
    35581 tattacagca ctcattcttc caaatgctat caaagaagca tttgtggcct acaaaaatat
    35641 cctagactac gacagcaacc tcattatgca aaaggccctg tcactctata ttgacagtca
    35701 attgtttgaa aaaaatcgtt tggctcgctt gaccaatcat gaatcttacc aaaaacaaat
    35761 cgaggaaagg ataactaaaa caccttgtcc ccttcctcat tatcccctac acgatggttt
    35821 attgctagac ctgagacagt atcctaaaat cgccagtctc aaacacagtc aaccgggctt
    35881 ggacttcttt gaagaggcct atttaagtac ctgtccttat caatttgcca aggtgtccct
    35941 agacaatctg gaaaatgttt taaactattt aaaagcagaa ttggaatgac atccaactct
    36001 gctttttctt attcttcaac ttcagttaga cttgctgctt tttcaagata gctttggtaa
    36061 attccttcat ccttaagttt ttggatgacc ttgtctacca cttctttcaa atcatcacta
    36121 ttttttctaa gagcaacggc attggcgtcg ccgtccttca tcttcaagct gacagttgcg
    36181 acagctaagc cagcgttttt agcagcataa ctaagtgcaa caggctcatc catatgaaca
    36241 gcatctactt ttccagcctg caattcattg actgcttcac ccatattagt tagggaagtt
    36301 aattgagctt ttggcaattg ttccttgacc attgattctg gaacagtccc tttttgggct
    36361 gcaatattag cactttctag gctagttaaa tccttgtatt tttccacatc agccttacga
    36421 accaagaaac taatcttgtt ttcatagtat gggattgaaa aatcaaagac ttcttttctc
    36481 tcgtcagtag cactaattcc tgcaactgct aggtcagcct taccagtttg aagactggtc
    36541 aaaacattgt caaaactcat gcttgagatt tccaacttaa ccccaagttc atcagcgata
    36601 gcctgagcca tgtcgatgtc tgcaccgact acctggttct ttccatcaac caatgattga
    36661 aattcaaagg gtgcatagtc aggactggtt gccacaacta atttcccctt ttgcttaatt
    36721 gcctcaacag ctgactgaga accattagaa cctgactggc aagctactaa gaagaaactt
    36781 gcaagaaaat tacataaaac aaatatccat ttttttgatt tcataaataa acaacctctc
    36841 tgttaatttt gtataattat aacgatatcc aagttacttg tcaagtgttt tttaaatttt
    36901 tatctcaaaa atattttttc gttcaaaaaa aggagccatc agttgatttc aagctccttt
    36961 ttatacagaa ttaaactatt ttatagttcg acaatcttac ctgtttcaaa gtagacaacc
    37021 cattcacaga tatttttagc atagtcaccg atacgctcca agtaggaaat aacttggaaa
    37081 taatcacgac ccgtaacaat ggcttctgga tttttcttaa tctcttcagt cgcaaggtca
    37141 cggatagttt caaaatagtg gttaatttgc tcatccatgg aggccacccg gtatgcgtcg
    37201 tcaacagaac cattaagata aagatcaagt gctgcttcaa caacgctttt aacttcacgt
    37261 cccatttttt taatttcttc ctctacagct ggaatacgtt cttccccctt catacggatg
    37321 gttgcctggg caatggctac agcgtgatcc cccatacgct ccacatctga tacagcctta
    37381 aggacagtca agactgtacg caaatcttga gagactggtt gttggagtgc gatcatttca
    37441 aatgatttct tttccagttt cacttcgtat tcatttactt ctgcatcatc ttcgatgacc
    37501 tcttttgcca ggtcacggtc atgcgtgaca aaagcacgta ccgtacgatt gatttgtgag
    37561 agcacttctt gtcccatagc gtagaactgg ttatgtaatt tctctaaatc ttcttcaaat
    37621 tgagatcgta acatctttca tctccttatc caaattttcc tgtaatatag tcttccgttt
    37681 ccttgtgttg gggatcaagg aacatctgct tggtatcatt aaattcaatc aaatctccat
    37741 ctaggaaaaa tcctgtctta tcagagatac gtgaagcttg ctgcatggaa cgggttacca
    37801 gaagcatggt gtacttgtct tttagaccat acaaggtttc ctcaatttta ccagctgaaa
    37861 tcggatccaa agccgaagtt ggctcatcca agaggatgat tttaggacta gttgccaaga
    37921 cacgggccac gcagacacgc tgctgttgac cacctgacaa tccaatagct gaatcatata
    37981 gacgatcctt gacctcatcc cagatagagg caccttgcaa ggctttttct acggcttcat
    38041 ccagaacctg cttatcctta attccattga tacgaagccc gtagacaaca ttctcataga
    38101 tagtcatagg gaaaggatta ggttgttgga aaaccattcc gatttcctta cgtaattcaa
    38161 ccgtatctgt acgcggactg tagatgttgt gaccattgta caccacggat ccagttgtgg
    38221 tcacctctgg attgagatct cccatgcggt tgagagactt gaggagggtt gacttccctg
    38281 atccagatgg accaatcaag gctgtaattt ccttaggttg gaaagatagg gaaacactat
    38341 tcaaagcctt ctttttatta taataaacgg acaggtctga tacctgtaaa atcgcatctg
    38401 tcatacggtt tcctttctaa ccaaagtgac cagatacata gtcattggtg gactgtagct
    38461 tggcattttg gaaaatagtt gcagtcttgt catactcaat caaatcaccc aagtaaaaga
    38521 agcctgtata gtcacttgca cgagcagcct gctgcatatt atgcgttaca atgatgatgg
    38581 taaagttttt cttgagctca aacatggtct cttctagttg catggtcgca atcggatcca
    38641 aggctgaggc tggctcatcc attaagagga tatctggctt aacagagatg gcacgagcga
    38701 tacagagacg ttgttgctga ccacctgata aggtcaaggc tgacttgtgg agatcgtctt
    38761 taacctgatc ccagagggca gcctgacgaa gggaggtttc tacgatttca tctaggactt
    38821 gcttatcctt aactccagca cgttcatgcg caaaggtaat attacggtaa attgacttag
    38881 caaatggatt ggggcgttga aaaaccattc caatgtgttt acgcatttca taaacgttga
    38941 tttctggacg gttgacatca attccacgat agagaatctg cccagttact ttagcaatat
    39001 caatggtatc attcatgcga ttgagactgc gtaagtaggt agatttcccc gatcccgacg
    39061 gaccaatcaa agctgtaatt ttatttcttt caaattgcat atcaatcccc ttaatggatt
    39121 catttttacc atagtaaaca tggacatcct tagtagaaag ggctactttt tcttcaggaa
    39181 aggtaaggat atgcttctca tcccagttat atgttgacat ggcttctcct ttaggcagcg
    39241 gttaatttct tgtgtagata gcttccgaac ttacgagctc caaagttaaa aatcaggata
    39301 aagatcagga gcacagcggc agaacctgct gatacaatgg ttccatctgg aatagtgcct
    39361 tcactattga ctttccagat atggacagcc aaggtttctg cttgacggaa gatagagatg
    39421 gggctagtca cactgaggat attccagtta gaccagtcaa gagctggcgc cgattgccct
    39481 gctgtataga tcagagctgc agcttcgcca aagatacgac cagatgccaa gacgacaccc
    39541 gttacaatac ctggaagcgc ttctggaata acaacatgaa ccactgtctc ccagcgagaa
    39601 atcccaagag ccagaccagc ctcacgttgg gtatggtgaa cgtgtttcaa actatcctct
    39661 acattacgcg tcatctgagg caagttaaag actgtcaagg ccaaggcacc tgaaatgatt
    39721 gaaaacccat actcaaactg gactacaaag atcaagtaac caaagagacc caccaccact
    39781 gatggtaaag aggacaagat ttcaatacaa gtccgcacaa agttggtaac aggacctttt
    39841 ttagcatatt cagccaagta aatcccagct cccatagaaa gaggtacaga aataatcaag
    39901 gtaatgacca ataggaaaaa ggaattgtaa agctgaatgc caatcccacc acctgcttga
    39961 aaagcagaag accttccagt caagaaagac caagagatat ggggcaagcc ccgaaccaag
    40021 atatagagaa ttaaggaagc caagattgtc acaatgatgc tagcaatcgt atagaggaca
    40081 gctgttgcaa gtttatctaa tttcttagcg cgcataattt ttctttcctc tttctttcgt
    40141 aatcaattta atcacactgt taaaaactaa actcatcaag agcagtacca aggccagtga
    40201 ccagagaaca ttattattta cagttcccat gacagtgttc ccaattccca tagttaatat
    40261 agaagttaaa gttgcagctg gtgtggtcaa ggaagttggg ataacagctg agtttccgac
    40321 aaccatctgg atagctaaag cctcaccaaa ggcacgcgcc atcccaaaga ccactgcagt
    40381 gaaaatacca gaacgggccg ccttcaagat cacacgccag atagtctgcc agcgagtggc
    40441 tcccatagcg aaactggcct cacgataata acgaggaacc gcacgcaagc tatccgttgt
    40501 cataaaggtt acggtcggca aaatcatgac aaagaggacg gaaatccctg acaaaatccc
    40561 aaaaccagtc ccaccaaaga cactgcgaac aaagggaacg acgacttgca agccaataaa
    40621 tccgtacact actgaaggaa tcccaaccag gagttcaata gctggttgca aaatcttcgc
    40681 cccttttggt gatacttcgg tcataaaaac tgctgcacca atagcaaagg gtgttgcgat
    40741 aagggctgag agaatggtaa cgataaagga acccaaaatc ataggaaggg caccaaattc
    40801 tttactagaa ggattccaag ttcttcccaa aagaaagtca aagatattca caccattgac
    40861 aaagaaggtc gacaagcctt tttgcgctac gaaaaccaaa atcatggcca caaggatgac
    40921 tatcaaagaa agacaggcaa aggtcaaacc ttttcctaat ttctccagac gagaattctt
    40981 tgatggaagc aacattttct tagctaattc ttcttgattc attattgtct cccttccaac
    41041 actgtcacag ttccggcagc atctttttca accttcattt ccttaatcgg aatatacttc
    41101 aatcctttga caatcccttc ttgggtctca tccgagagaa caaaattgag aaattctgca
    41161 gccaactcat tgggctgccc caatgtatac atatgctcat aagaccacaa gggccaatta
    41221 ttgctactta tattttctgg acttaagtca tagccattca acttcatgct tttgaccgaa
    41281 tcatctatat aggtaagaga taaataagag atagctcctg gactttttga tacgattgat
    41341 tttaccgctc catttgaatc ctgctcctga ctttgcatgg cagactgacc ttccataatg
    41401 acagtatcaa aggtagcacg agaaccagag ccggctgccc gattgataac agagatgggt
    41461 aagtccttac caccaacctc tttccaattg gttacctcac ctatgaagat ttgacgaagt
    41521 tgctctgtcg ttaggttatc aacatcaacc tccttattga caatcagagc caagccagct
    41581 accgcgacct tgtggtcaac aagagcagaa gcatcaattc cgtctttttc ctcagcaaat
    41641 acatctgagt ttcctatatc aactgcccca gactgaacct gggacaagcc tgtaccagaa
    41701 cctccccctt ggacattgac cgtttttcca acatggatcg tgccaaattc atctgccgct
    41761 acttcaacca agggttgcaa ggcagttgag ccaacagccg ttatggattc tccacgatca
    41821 atccagctag cacagcctac taaacaagcc gtcagccaaa aagcgataag agacagagca
    41881 agcttttttc tttttttcac tgtttttctc ctcgaaaata attatgaata ctgtgaattt
    41941 tttaagtagt tctttatgag ttgacgcatg aattcttacc aaatttctgc gcaattgatt
    42001 atttatataa tataggctat attactcttt cctaacctcc ttttttcata tgtggataaa
    42061 atctcttgtc tatcccttcc cccattgtca cccattatag tcatttcgtg tctctttttc
    42121 ccctttttaa tgcaagggaa attactctcc ttagatgata atccaaaagc tagaaaggta
    42181 tctcaaacct ctctactctc ccagactagt ttacaactaa aaggaaaaga ttctatttta
    42241 tgagaaatct agtttacaag cggtaagaac gctaataact aaacttcttg tactctttga
    42301 aaatctcttc aaaccagtgt tttgagctat ctatggctag cttcctagtt tgctctttga
    42361 ttttcattga gtagtaaaac tacatgtaat ggcaatcaag atatcaagaa tcatcctact
    42421 aaaaaaatcc atactttcac tataacatag aataagatat ttgactagca ttttcatttg
    42481 aatctgaggc cttttggaaa ataatttttc aaaacatttc cagtaacctt tgcaaagccc
    42541 aagccattgc ctttaaccaa aacttggtac caaccatttg gcagactttc tgccagctga
    42601 acgatttctc cagccgcata cttgacaaac gcttcttggc caatttcaac cgactgttcg
    42661 acctgactcg gtttcaaggc taaaccaaga gcgaaactgg gctcaaagcg tttcttctta
    42721 aaagtgccca gatgcagtcc attgcgagca atcttgagct tccctaaatc tggcaaaagt
    42781 tctggcaaga gataaagctg gtctccaaaa gtctgcaaga tacccggtag attgaccttc
    42841 aaatggtttt gggcaaattc ctgccacaag gcaacttgtt cacggctgag gttactctta
    42901 cttgccttaa atttaggagc tggattgtta cccttaaact gtagatgggc aacaaactga
    42961 ccctctccct taaactgatg agggtacatc cgagccgttt ctggcaggtc aataccagct
    43021 accattccat tgatatgctc tactggcaac aagtcaaaat catactcttc cagcaaccaa
    43081 ttgacaatct cttcgttttc ctcgggtgcc caggtacagg tcgaataaac cagacgacca
    43141 ccttcagcta acatggtcac tgcatcctcc agaatttctc tttgcaagct agcacattga
    43201 ctcggataat ctaagctcca atagtccata gcatcaggtt gcttacgaaa cattccttca
    43261 ccagagcaag gggcatcaag aacgattaag tcaaaatagc ctttaaagac cttgaccaag
    43321 cggtcggcag attcattggt caccacgaca tttgtcgctc caaaacgctc catgttttca
    43381 accaaaatct tagcccgttt gcttgaaatt tcattggaaa caagtagccc ctcccctgct
    43441 agataggctg ccagttgagt tgatttgccc cccggtgcag cagccaagtc caagaccttc
    43501 ataccaggac tgggttgagc tacttgagcc accatttgag cagcaggttc ttgcgaataa
    43561 actaaacctg tagcatgctc aggcgatttc cctgaaacct tcccatagtg gccccaaggg
    43621 gtttgagtaa tggcatcaga aaaggaaagt tgctcttctt ttaagggatt gacccgaaag
    43681 gccgaaaccg cttcctcctc aaaagaggca agaaaatctc ttgcctcatc tcctagtatc
    43741 tctttatatt tttcaacaaa tccttctgga aattgcattt aagttctttt cctttcgtaa
    43801 atataggact gaatttcctc ctgcatctca agaggcacca tcatgaccgg ctgtctggtt
    43861 tgaaaatcag gagcttcacc aaaaagggtc acaacccgat agcccagact ttcccctaaa
    43921 atactagctg cggcataatc ccatggttgc agataagtga gataggtcaa caaacgccct
    43981 gacaaaatct tggcaaaact aatggccgca cttccataga cacgaacacc aagaaccgct
    44041 cggctcaaat cagccagccc ccattcattg gtttccagca taccactatt ccctgcaatg
    44101 agaaaatctc caagtggttt agttttaaaa ggagctaggg gcctatcatt tagacaaact
    44161 ggaaattccc caccaccgtg gtaacaatcc cctttgacca catcataaat cagaccaaac
    44221 tgtccctgac cattttcaaa ataagccatc ataacagcaa aatcttcctg ctgggctaca
    44281 aaattattgg taccatcaat gggatcaatg acccaaacct tgccctcttg aaccgaggct
    44341 cgcagacaac cttcttcagc acaaatctta tcctcaggat aacgggacaa aatctcacca
    44401 accaagagtt cctgaacttc tttgtccagt ctggtcacca aatctgttgg agaggacttg
    44461 gtttcaacac gcaagtcttc ctgcatatgg tcaagaatgt actgacctgc tttcttaaca
    44521 agctctttag caaattcaaa tttactttcc aagagaaatc tttccttccc ctttttcttt
    44581 ggcagcctga actgctcggt aaagtgaata gccactaacc gtttcaaatt ctcgtcccaa
    44641 acgtttctct tcgctcttgc ttggcacgac cgctttgaat cccttatagg agtccagtaa
    44701 ctttttagcc tctactttgc cttcataggc agcttcaaca tcattaaaaa aagaaagcac
    44761 tgaagcaagt tcttcagtgc tccacgacaa atctagtggg taactatact gtttgttcat
    44821 taactaatac cagctctcat tcttgcttct tttagttctt gcttacgata actacgaggg
    44881 agaaaagcac gaatctcatc ttcattaaaa ccgatttgca tacgcttggc atcaataata
    44941 attggacgac gcaaaagact aggatactgc tcaatcaaat gaagcaattc cgataccgaa
    45001 atactctcta catcaatatt caatttttga aaaatttttg aacgagttga aatgatgtca
    45061 tcagtaccat tttcggtcaa ggaaaggatg tgttgcaatt cttttcttgt taaaggactg
    45121 gtcataatat tgtgttccac aaagggaacc ttatgttttt ctaaccaggc cttagcctta
    45181 cgacatgatg tacagctcgg tgatagaaat agtgtaatca tgcttttctc ttcttatcta
    45241 tactttgcta cttctattat acaaaaaaat aaggcgcttg actagggatt tttagaaaaa
    45301 aagcctattt tttcaagaaa aataggctgt ttgcgaacga ttgacacaat tggatttggt
    45361 taattcactc ttaacgatgg ttttaaacga tatatatttt tatatatgca aattaaaaac
    45421 atctttcatt tcacttccta cgacttttca gacacagata gccaaagaag ctttcataga
    45481 gggcaaaaaa gaggaggaag gcatgaagaa agaaggtctc tggcaaaatc ataataacag
    45541 gatccttggc tggatcaaaa agccaggtat catctcccac aaagagaatt tgatggaaaa
    45601 gagtaaagaa ttggtcaaaa ccaatcaaaa ctcccccaag tccaatcatc acaggtaaga
    45661 ctactagagc caggagactt tttcgataaa gagacaaaaa gtcctttttc acaatcctat
    45721 tgacaaagac atagaaactt ggcagtgtca ctagagctac tagctgaacc aaatgaaaga
    45781 gattcttgac cactgcgaaa tggtgcagac cagctgctga cgaacgaaaa tcaggcatct
    45841 gtaagacctg actaaaagga ttggtcagat aattcatcaa gatatgaaaa ttgtattgaa
    45901 tggtttctgg ttttagatag actcgattcg ttaagtttag ccactgaatc tccataggat
    45961 agaaaatcca agccagataa atggtcagaa ggattgagag ggagaggaga aagagcatag
    46021 agccccaaaa ggtcaattta gttttcatca aaatcccact ccgcaaggct agaaaccaca
    46081 tgtgtcggtg cgattggcag gccagctact tcttctgcct tggtaaaacc tgtcgtcacc
    46141 aagagcgttg gaatgccatt gtcaatccca gcccggatat cagtcaaata attgtcccca
    46201 accatgatta actcttcacg ttccaaacct aagtgctcaa ccgccttgtc cataatgatg
    46261 gcatttggtt ttccgatata aaccggcttc actcgtgtcg ctacttcaag cagcgtaatc
    46321 agtgagccag cacctggcaa aagaccgcgt tccgtcggga tgttgaggtc aggattggtt
    46381 ccgataaaat gggcaccctt ttgaatagca agagttgctg tggcaaattt ttcatagtcg
    46441 acttgccaat ccagaccaac taccacgtag gcaggttttt ccttgtcttc cacataacca
    46501 gccgccttga tggcttcctt gagtcctgct tctccgacga catagacggt cttttcaagc
    46561 cccaaatcat tcatatagtc gatggttgcc aaagtcgctg tgtagacagt cgataggggc
    46621 gtatcgatat taaaattctg agccaacatc tccttaacac tctctggagt gcgggttgta
    46681 ttgttggtta caaagagata gggaatgtcc cgcttttgca attcatgaac aaaagtctct
    46741 ccagcaggga ttcggtcttt ccccttataa atggttccgt ctaaatcaat taaatagcct
    46801 ttatatttca tctatttctc cctaagcctt ttttatttct tgccaagtaa tgattgcttg
    46861 ggcattgata accccatcac ttgtaatttc atgcttgctt tccagtccag tccgttcaac
    46921 agccgatgta atcaccccac ctggtcgaac ttccttgaca tacttgaggt tgattttctt
    46981 gggaatatag tgggtcaaaa aatccgctcc catgacctca aaaatccagt ccaagtattt
    47041 actgttattg acatgaccat tcatatccaa gtcgtaaaaa cgaacatggt aatccttgct
    47101 gatcggttct tccaaggact catacttcgg tccacggata agttttttat caaaatcaga
    47161 ctggtaagga gccacaatct caggttcaac aacatggact tttcgactgt cgcggtccat
    47221 gagaacaaag gtcgccatca tgtggatgag ctcctgctcc gcttcattat aaatagtaaa
    47281 gcgacggtag caaaaaagtc gattgtagct caaggcttcc gtttcgatgg taatttcttc
    47341 cgcaaaacga ggcaaacgaa ccacctcaat atcatattct acgataatcc agaccagatt
    47401 atattcttcc aaaatggcct tatcactaac tcccagttca atcgactgca tccctgaaac
    47461 ttgcagtgac agcaaaatca catctggaag tttgatatga ccgttcatat cagccatatc
    47521 aaaaggaatt ttcattttca tttgataagt taagcccatg atcctactcc aaaataaatc
    47581 gttctgctac agtatctccc aaaaagagac ctctctttgt catgcgaacg tggtcaccct
    47641 caatctgcat gaggccttgt tgaaccaaat ctctgacaat ttctccataa agtccagcaa
    47701 aagactgtcc aaatttttcc tcaaatcgcg ccatggaaac cccggatttc ttgcggagtc
    47761 ccaagaacat ttcttcttcc atttgctcct tttgactcag gtgatcttct gtaatacaag
    47821 cattgccttc ctcaaccgca ctgagataat gacgaatggg accatgattt ttatagcgta
    47881 ctccattgac ataaccagat gcccctgcac caataccata gtattcagca ttgtcccagt
    47941 acatgagatt gtgacgactt tcaaaaccgg gtttggagaa attagaaatc tcataatgct
    48001 caaaacccgc tcgctccagc tctgcaatga tgtactcaaa catctccgct tctagttcct
    48061 ccttaggcag aggcaatttc ccacgtcgca tccggttcat aaagaccgta tggttttcta
    48121 aaatcaaact atacaaactc atgtggggaa tatccagtcc aatggcttta gccacatttt
    48181 cctttacttg ctccatggtc tgaccaggca gagcataaat caaatcaatg gagatgttgt
    48241 caaaaccagc cagtttcaga cgatcgatat tttcataaat atccttctcc aaatgactgc
    48301 gcccaatctt tttcaacatc ttatcatcaa aggtctggac acctagcgaa acacgattga
    48361 cagccgaatt tttcaaaaca gctatcttat ccgcatccaa atcgcctgga ttggcttcaa
    48421 tggtcaactc ttccaagaca gacaagtcca agtttttagt caagccattc agtaacacct
    48481 ccagttgcgg agccgacagg gctgtcggtg ttccaccacc gatataaagg gttgacaact
    48541 tttcaatatc ataagaacga aactcttcca gcagatgctc taaatagctg tcgactggct
    48601 gatttttgat gaagaccttt gaaaaatcac aataataaca aatctgggta caaaatggga
    48661 tgtgcacata ggctgacgtt ggttttttct gcatagtaat tattatacca caaagactag
    48721 attccagata aaaatcacca tccccagata catagtccgt ccggagatgg tgatggttta
    48781 ttcttctgtt atatcaatca caatctcttc tgagtcatca agagcttcgg ctttttcttg
    48841 ccattgttcc ttgagattat ttaattgatt ttttgatgct tctgtcgctt gaaaagcata
    48901 ggatttagct tgagcaagta tactgtccac agtgatttca cctgactcaa cctgttcttt
    48961 tgttttcaga acaaaatctg tagcctgctc cttaacttct gtcagttttt cacagacttg
    49021 ctccttggca tactccggat cttctctcaa atcatctaga aaatcttgag cctgactgca
    49081 aacttgtttg cccttatcac ttgttaaaaa caaggcaaga gctgcacctg aaaccgttcc
    49141 taaaaggatt gaggataatt tacccataag gattctcctt ttttattttt tgaaaaattt
    49201 acttgcaaga cgaagagctg acagacttgc accagtcttg agtgtttttg aaccagctga
    49261 tgaagctttc ttgctcaaga cacgcgcatg gtcattgagg tctgaaacag atagagataa
    49321 atctgcaaca gcactgaaga gtggatcaat cgtagccacc ttgacattga tatcatctgc
    49381 caagacattg accttagcca acaactcatt ggtgtgatgc aaggtcacat ccacatctga
    49441 agtcaaggtt ttaatcgtct tttctgtttc atcgatgaca cgaccaagct tttgtacagt
    49501 aatgatcaga tagaccaaaa agacaatcaa agctagggca acaagaatat atgcaacttc
    49561 taacatttat ttttcctcct ctgtaatata gtaaggggcc ttctttcgat tttgataaat
    49621 aacgatcatt ataccgagac cgataaggac aactgacagc cattgggaca ctcgaaggct
    49681 gaagaacatg agactatctg ttcgcatacc ttcgatgacc atacgaccga aaccatacca
    49741 aatcaagtaa aaggccgtga tatgacctcg tctgagactc ttccatttcc gtctaaaaat
    49801 cagaatcaaa gcaaagccaa gcagattcca tagagactca taaaggaaag tcggttgacg
    49861 gtagctcccc tcaatataca tctggtcacg gataaagcca ggtagataat ccagattatc
    49921 cactgttgca ccataagctt cttggttaaa gaaattaccc caacgcccca aactttgagc
    49981 aatcataacg ctaggcgccg caatatctag aaaatcccaa gtattgatga gtttacggtc
    50041 agcaaagata tagagcacaa gagccccagt tatcaaacca ccgtaaatgg ccaaaccacc
    50101 attccaaatg gcaaaaatct ctcctaaatt ctgactatag taatcaaatc ggaaaataac
    50161 atagtagaga cgagctccta aaatagccaa gggaaaggct actaagataa aatctaaaat
    50221 atcgtctggt atgatcttct ttctaggtgc ttctttcatg gtcaaataaa ccgcaagaat
    50281 caagcctgtc acaatacata aggcatacca acgaatggct aggggtccta gttgaatagc
    50341 aattggatca agcattttgc acctcatttc gagcaatgag acttgtcagt cgttcgtcga
    50401 acaaacgggt cgcatcaaag cccatttcct tggcacgata attcatggca gctgcctcaa
    50461 tcacaacaga gatattacga cctgttttaa ctggaatacg aatacgagga atggctacgc
    50521 cagaaacttc aagttcctct gcattgtttc caagacgatc aaaggtctta tgtgtatcgt
    50581 aattttccaa atagacagca agctgaacct gtgaagaatc cttgacagca ctcgcaccgt
    50641 agagactcat aacatcgata ataccaaccc cacgaatttc aatcaagtgt ttcaaaattt
    50701 cagctggttc accccagaga gtaatctcat ccttggcaaa gatatcgaca cggtcatcgg
    50761 ctaccaaacg gtgaccacgt ttgacaagct caagacctgt ctcgctctta ccaattccac
    50821 tatctccctg aatcaagacg cccatcccat aaatatccat caagacaccg tgcacactgg
    50881 tacgttctgc caaacgagaa tccagatagc tagataactc tccagataaa cgactggtag
    50941 ctgcacggct ggttaaaata gcaatcttac attctctagc agcctttaac atctcctctg
    51001 gaaccaccaa accacgagca acaatgactg ctggtgtctc aggtagaaac atttttttca
    51061 aaacttcata acggctgttg gaaggcatgc tgatcagata agaccactcc ttcatcccca
    51121 aaagttgaat ccgctctggt gtatagtagt caaaatagcc tgtcatttca agaccaggtc
    51181 gcgtaatatc cgctgtattg atttcctttt caagcaactc tggttcacca tagacaatgt
    51241 ctagtctaag cttttcaatc acttctttta ctaaaaccga catcatttcc tccttcaaat
    51301 gagttcttct ctctattata tcaaattgta ggaggaagtt tcagattttt gcaggctttg
    51361 gagtatttat ttaaaagaaa aaggactaga tttctctagc ctttcatttc aattagaatt
    51421 ttttacgttt acgagctact tctgatttac gtttacgttt tacagaaggt ttttcataga
    51481 attcacgttt gcgtgtttct tgaagagtac cagctttagt aaccgcacgt ttgaaacggc
    51541 gaagtgcgtc gtcaagagat tcattcttac gtactactgt tttagacatt tttttcactc
    51601 ccttcaagtt caatatctat ttcattctac acgtaaaagg aataattgtc aagcaaaaat
    51661 gcggtttaat tttgattttt tcttccattt atacaagagt tgaaagcgtt caatagaaca
    51721 ttgctttttt atttttcgag taagctaagc gcttcagcat ctgcgatgat ggttacatca
    51781 gggtgatttt gaaggctact tgcaggtagg ttctcagtca ctgggccaga tactgttccg
    51841 gcaatggctt ctgctttcga ctcaccgtaa gcaaaaagaa taatagactt ggcatccaaa
    51901 atgtttttaa tccccattga aatagcttgg gttgggacgt cttcaatctt ggcaaagaag
    51961 cgtgcattgg cttcgatagt agactggtca agttctacta gatgcgtttg actgtcaaat
    52021 ggagtaccag gctcattaaa gccgatatgc ccattgcgac cgattcccaa gatttggagg
    52081 tcaactggat ggtcagccaa aatttggttg tagcgttcaa cttcagcttc agcattgtcc
    52141 ttaacaccac gaggcaagaa actttcttta aatggttttt ggttgaacaa gttttcttgc
    52201 atgaagtaac gataagattg tggattgtcc ccatcaaggc ccacatactc atcaaggttg
    52261 acactggtta gatttgaaaa atcaaggtca ctctcaacaa tttccttgta aaattcaagt
    52321 gggctacttc ctgtcgcaag tcctagagtt tgagctccat tagccaattt ttccttcaaa
    52381 atctcaaaag caacttttcc accttgaact tggttttcaa ctttaataac tttcatcttt
    52441 tcatcctcca tttctgtcta tatttattat atggtataga ccaatttttg tcaagtgaaa
    52501 acgatttaat ttctaaaaaa agagcgtcca aacttgaaac gtgttataat ggataggatt
    52561 agaacttaga aagaatgaac aaatatatga atacagctga ttttgatttc cacttgccag
    52621 aggaattgat tgcccaaacg ccccttgaaa aacgtgatgc ctccaaactc ctcatcgtca
    52681 accgtgagac aggagaaatg caagataaac acttctactc tattattgat atgctggaac
    52741 ctggtgatgc ccttgtcatg aacgacaccc gagttctccc tgcccgcctc tatggtcaaa
    52801 aagtggagac aggaggtcat gtggaacttc tcctccttaa gaacactagt ggagacgagt
    52861 gggaagttct ggctaaacct gccaaacgcc tcaaggtcgg tactcgtatc agctttggtg
    52921 atggccgcct cagcgctgtc gttacagaag aattgaccca cgggggacgc attgtccgct
    52981 ttgaatacca aggaattttc ctagaagtct tggaaagtct gggagaaatg cctctgccac
    53041 cttatatcca cgaaaaatta gatgaccgtg aacgttatca aaccgtctac gccaaggaaa
    53101 gcggctctgc tgcagcaccg actgctggtc ttcacttcac caaagaactg ctggcagaaa
    53161 tccaagctaa gggtgttcat ctagtctatc tgactctcca tgtcggactc ggaaccttta
    53221 gacctgtttc tgtggataat ctggacgaac acgaaatgca ctcagagttc tatcaacttt
    53281 ctgaggaagc tgctgccacc cttcgctctg tcaaagaaaa tggtggtcgc gtcatcgctg
    53341 tcggaaccac ttctatccgc accttggaaa ctattggttc caagtttgat gggcaaatcc
    53401 aagcagattc tggttggacc aatatcttta tcaaacctgg gtatgagtgg aaggtcgtgg
    53461 atgccttctc aaccaacttc catctgccaa aatcaactct ggtcatgttg gtttctgcct
    53521 ttgcaggccg tgaattagtc ttagatgcct accaccatgc catccaagaa cactaccgct
    53581 tcttcagttt tggtgacgcc atgtttattt attgagaaag aatttctcta attcttctaa
    53641 taccaataaa tcgctaagat attatttcaa agaacatcta caattgaaac tctagctagc
    53701 tgtagaagac gcctagtaca ttgaaattaa aatgcttccc cctagcttcg aaaatattgc
    53761 catagattgc gttgactctc caaattgatt catctatatt ttatttcagc ttcctatatt
    53821 ttcttcgctg tttgtaaatc aaaatgcaag acacatgagt agcaccatat ttgttactct
    53881 tatctgtcct ctcaagagac tattatgagt tatttcagaa tcattcacta ctttgaccct
    53941 gactctcctt agtctcaaaa tcaaagactt atactcttca aaaatctctt caaaccgcgt
    54001 caacgtcacc ttggattata tatgtgactg acttcgtcag ttctatctac aacctcaaag
    54061 cagtactttg agcaacctgc gactagtttt ctagtttgct ctttgatttt cattgagtat
    54121 taaacaaaaa gtgaacaaat ctgaattcta atgtacagaa gactaggctt gttcactttt
    54181 ttatagtcgc tataagatga ccttatctat agctttttat atataattat atattcagac
    54241 atactattat caattttgtc gcagggagga atctgttaac gcacccattc accattatca
    54301 ttgactctat agccatctat acttgtattg accgctaact cacccgatgt atttacataa
    54361 taccatttac caccaacttg gaaccattga ttgactttca tagaaccgtt gctgttgagg
    54421 tagtaccatg aaccattaac ttgtacccaa cctgttgcca tggaaccatc agtattataa
    54481 aaataccaca taccattttc ttgtttccag cctgttgttg gagcaactgc tttagctggt
    54541 tctactgcta catctgttcc ttggttagat gtaacagata caggatacga aggaatagat
    54601 gattgctcag gaacaacaac tttttcaggt tctctcgtcc ctctccttat acgtcttttt
    54661 accatctctt tagtaatttg acgagaagta gtttcttcaa ttgttccatc acgttcatct
    54721 acagtataga ttgtagtaag agtaatttac caatttctcc tacttcttct acttcttgac
    54781 ttttatcaag agttgggcca tcgagatatt ctgtttcgat tgaaatttct tggacaagaa
    54841 cttggggctt ggttcctttt ttaacaactc ttgtttgaga gtcttctttt tgacttaaag
    54901 tactctcagt tacttgtcca ctctttccat ctacatcata agttatcgtt gtaactattt
    54961 tcccattctt tcctagagta atctcttgct cctgtcctgc agaaaggtca ttgtctgctt
    55021 catatttagt agcaaatgga acaaaaactt cttcaacctt gcttttagct ggaactttga
    55081 taactgtatc cgtggcttct tttctatcaa cagtaacctg ttcggtaaca tgaccagtct
    55141 ctggattaac atcgtaggtc cttgtcgtag ttacatagcc atcctctcca tcaattgtaa
    55201 caggattttc actacggtct tttgtttcat ctttttcata acgaattcgc gtacttgaaa
    55261 ttttcttggt tactacctta ggtttagtcg ctacttttac aataatatcc ccattgtcag
    55321 cgtcatcata ctctattccc tcttctttat ctctagtatc atctctgaca tattgaatcc
    55381 catcagcagc atgaacaaaa cttgtattca gattcctcct aaaaataaag ttagcccgat
    55441 taccgcagaa ccaaaaatct ttccgagttt acgtattgca tagcgcttat tagtattaga
    55501 ttttgccatt acatcctact tctagtatag catcttttct atcaaacgtt aaacaatata
    55561 ctttatatat aaaatagact tagaatgata tattgattat tgaactaaca ctttaactat
    55621 atcgtaatca atctcatata taaaggattg cagacatctt atctaaatac atgctaatat
    55681 atttagatac aaacattcca acttgataat tttcactcat ctttcatcat tccttataca
    55741 actatgcagt ataaatagaa tagttttctc atcagaatga gactatttta atattagata
    55801 atttgataga aaaaacatga ataaaattgg ttgaatttaa ttccctaact cgatagagga
    55861 ttctatttta aatttaacaa cagctaggat tacactataa aaagtacatt accacctgtt
    55921 cggctggaga atctagtcga ttaggtccct cttagttaca agcttaaagc gattttttaa
    55981 ctaatactaa accagattaa agaaggaact agaacatctg tcttgtacta atcaatatgc
    56041 tattttaaag tttcaaataa acttggaatg ctaattatta tatttacaat aaatagttga
    56101 cttcgataga aacagaaaat agaattcaac attcttccct acttatacca taataaataa
    56161 gatccgcaag atagcctttt ctctctacac cattaacaat ggtttgtaga taggacattc
    56221 cagccttttc catgacacga cctgaagctg ggttgagact ggcataacgt gctctgacct
    56281 tttgaaaacc tgcttgagta aaacaaaagt ccaagatagc tttcaaggcc tctgtcatca
    56341 taccatgtcc ccagtaagcc ttgcctagca catagccgat ttcacagctt aaatcagcct
    56401 cgtctatctt aacaatgctg atatctccta tcacttgctc tgggttttct tttagacaaa
    56461 tggcccattt ataatagttg agattagtat aggaagcaac ccaattgcga atcgagtttc
    56521 gagtgatttc gatatcagga tggggatccc aggtaacata ggtcagattc tcagcggatg
    56581 aagcccaatt ttgaaacata gcttctgcat cactctccac aaatcttctt aaaatcaaac
    56641 gttctgtctg taatatttgc gtaccaatag atttcatgat gctacctcac ttccttattt
    56701 ctatgctcgt agtaaaaagg ctcaactcag taacagctag aaaacgagtt tgtcttctaa
    56761 tttcttgacg caatcgctgc ctggtttgaa atgcgatcta gcaagctttt tcaaacctag
    56821 tcatcgttgc aggggtaaga cgatgaaatc gaactcttcg agttaccgaa tctgcctcat
    56881 tttcttattt ctaaactcgg ggttcaagat cccccagacc ttctctcact ttcttatttt
    56941 aagatgagag gctgaaaacc tccagtggag gtttttcttg ctttttaatt tcagggcaag
    57001 aagctaaaaa ggtcccccgg acctttttac tcccaaaagt catcaaatac agtgatgggt
    57061 aagtggcgtt tgtgttggcc tttgtgccac cagttttcaa tggtcgcttg agcttctggg
    57121 ctgattgttt tgccttctag gtagtcgtca atctctgcgt aggtgactcc aagtgcgact
    57181 tcgtcagcta ggcctggttt atcttcttct aggtctgccg ttgggatttt ttcataaagg
    57241 gctggctctg cgccaagttt ctgcaagagc tgttttcctt ggcgtttatt gaggcggtaa
    57301 agagggagaa tatccgcacc gccgtcacca aacttggtaa agaaacctgt gatattttcc
    57361 gcggcgtggt ctgttccaat gaccgctccg ctatgggaac cagcaagggc atactgagca
    57421 atcatacggc aacgtgcctt gatattcccc ttgttgaagt ctgaaacagg actacctgtc
    57481 gcttcaactg cagctgtcat ggcatcagct gattccttga tattcacaac caagctgaca
    57541 tctggctgga tgaaggctag agctttttga gcatctgctt catcagcttg cactccgtat
    57601 ggcaggcgga cagcgataaa tttgtagcta tcgtctcccg tttcagctcg cagttcttcc
    57661 atagctaatt gcgccaaacg ccctgccaag gttgagtctt gtcccccaga aatccctagt
    57721 acaaaggttt ttaggaaggg atgttttttc agatatcttt ttaagaaatc aatagaacga
    57781 cggatttctt cctgggcatc aatcactggt ttgacaccca gctcttggat aatcgtttct
    57841 tgcaaactca ttcttcttct ccttcaccaa gggcttcctt gcgcatctta tcaatcaagt
    57901 ccatcttatc ttgccataca tcacgcgcca aatccactgg atagtgctgc ggattgagca
    57961 cacgcttata ctcatcccac aacttgtcaa attctttacg ggcataatcc tgaatgtcag
    58021 tcaaactagg caagttgtaa actaatattc cttctttgaa gatatccacc aagagaggaa
    58081 cggcatcaaa attacgaacc gtcttcttga tgtatgtata ggtcggatgg aacatcttga
    58141 tttctgtcat gtcgctaata tccacaccat cataagtgat atagtcgcct tctgacttgc
    58201 ctttttcacg actggtaatg cgccacacct gcttcttacc tggcgtagaa actttttcag
    58261 cattattaga cagcttaatc gtattgcgca tctgaccagt ttcatcttcg attgcaacaa
    58321 tcttgtaaac tgcaccaaga gctggctggt cataggctgt aatcagcttg gtacccacgc
    58381 cccagacatc aatcttggcc ttttgcatct tgagattgag gatagtattt tcgtccaaat
    58441 cattagaagc ataaatctta gcctctgtaa atccagcctc gtccagttgc tgacggactt
    58501 tcttagaaat gtaggcaata tccccagagt caatccgcac acccataaag ttaatctgat
    58561 cacccagctc acgcgccacc tgaatggcag ctggtacacc gatgcgaagg gtgtcatagg
    58621 tatccacaag aaagacacaa tttttgtggg tcgcagcgta agccttgaaa gcttcatagt
    58681 cattgccata aacctgtacc aaggcatggg catgggttcc caaaacagga atgtcaaaga
    58741 gcttacccgc acgcacgttg ctagttccat tggcgccacc aatcacagct gcgcgtgttc
    58801 cccagatggc cgcatccatt tcttgagccc gacgtgtccc aaactccatc aagggttcat
    58861 cttcgataac cgaacgaata cgagctgcct tcgtcgccac caaggtctgg tagttgacga
    58921 tgttcaaaag agccgtttcg accaactgac attgggctag aggtccttcc acctgcacaa
    58981 tcggttcatt agcaaaaacc aaatcccctt cttgggcaga acgaacggtc aactccaact
    59041 tgaaattgcg aaggtaatcc aagaacgccc catgataacc aagcgactcc aaataggcta
    59101 tatcactatc tgaaaaacgc aagtcttcaa gatagttcac aattctttcc aaacctgcaa
    59161 aaaccgcata gccgttctta aaaggctgtt ggcggaaata cacctcaaag accgccttct
    59221 tattgtgaat cccttggtca aagtaaacct gcatcatgtt gatctggtac aagtccgtgt
    59281 gcaatgtcaa actatcatct ggatacatac ttttcctact tccttagcta gaaacccatg
    59341 aaaattttca agaactttca tgtattccaa taaattagta ctattatatc acattttagc
    59401 tggattgaga aaagagtaac aagctattct ccactctcca attcatccat atcttgttca
    59461 aattttttct gagcccattc gccatagctc ttaagaccaa gattgccaat aaagatccac
    59521 ggaaggtaaa tgatataagt aatgacccaa gcagacaggt atttaaaatt caaaggattg
    59581 tgctgataaa tttctatgtt gaattgataa ttctgcaaca tcaaaagagc cgtaatagcc
    59641 aaggttagga aaaaacaacc caaaatcgta aaatgaaaac gactatagta ggtcactccc
    59701 agataacggg cacgattgaa aaagtaaaat gtccctatga tgataacgat tagcagcata
    59761 ttagaattaa aaaggcttgg tgctaatact gaaatgatat aagataggag cgacaaagcg
    59821 atgcagatat agaaactttc agagcccgct ttattgaaca gttgttcttc tctttcgtct
    59881 agtaattgat aataataaaa tctatttttc atcttcttcc tcccaaaata gttggtctag
    59941 ggttttccct aaacatctgc aaatggactg gcagagcgag agactgggat tgtatttccc
    60001 cgcttctatc aaaccaatag tctggcgcgt caccccgaca gcctctgcca gttgaccttg
    60061 tgttaaatca cgctctaccc gagctaattt taattttaaa tttttagcca ccttcgtcct
    60121 ccttatagtt ttaatactca tctactctta aaaaatccaa aaccaacaca agctatcagc
    60181 tatttattat aaccccatta atttgcactc cagtattatc ttcagccgaa aatcagtatt
    60241 ttaggttgtt tgaaataaac ttcctagttt actcttttat ttttatttag tattagcttt
    60301 agtaggatct tttaaacgag tttttattgc ttatatttct tgtttagttt agttggtttc
    60361 atatcactat tatataatgc ttttggaaat gagcctagta taagtcaaaa acgtgttgaa
    60421 tagtgaaagc aggagcatac caagatgact gattttttta ttgtatttta ggtatgcaaa
    60481 ataatactaa atgaaactaa aatgaatact tcttgctttt cttgagagtg aaaaagtaca
    60541 ataaaatgat tgtagtgatt accacaagat actgactaat agacatcgta tttgaagcca
    60601 caaatacagg taaagaataa aaaggaagaa gttcaattgc tttgataaac aaatcattac
    60661 tagtattcat catcatcgta tttaatatat tagggataaa gagtagtaaa gctactaaaa
    60721 taccaaatac caagccactt ttcaatttgt ataaataaaa aatgtaagat aatagaaaat
    60781 aaaacaggac taacaaaatt gtattgacta caatagctac tataaaatct aatcctaaat
    60841 cacctggaat acccaattta cttactatga ctagtaacac aatgccattc aaagcataaa
    60901 taatggaaac tgagatggca tatagaaaat tagacaagac gtaaatcatc cgattcttct
    60961 gtttatttaa tttcatgatt ataaccttcc tttattttga acgatttagg taaatatctt
    61021 taagcgtctc ttttttagtt tcaaaatcaa ctactttaat agagttttcg ttaaaaaatt
    61081 taaaaagctc actattttga atattcccag acatagtaat tctcaatccc tcttcctgaa
    61141 caatatcccc aaattcttgt ttggtaatga aaatgtctct atctgtagct gatgaaaaag
    61201 ctatctcaaa caagaaatta tgactatctt ttcctacttt ttgaaatgtc aaaagcccgc
    61261 tctccaagaa aagaaccctc tcacaaattt cttcaatgtc ttctaattta tgactcgata
    61321 ttaaaattcc cacgttttca tttaaagcta atttttttta gaaccgctaa aactatttgt
    61381 gatgattcaa tatctaaacc attagtcggt tcatctaaaa tcaatatatc aggttccgta
    61441 acgagagtta gaagcaaagc taatttttgt tttgtaccca aagaataggt ctttactttt
    61501 ttattaatag actgagtcaa atctaactct tggatcaaac ttctaaatct ttcttgattg
    61561 tagtcaacac catataaatt tgacaaatat tttaaattct ctaaacctgt tttagataaa
    61621 aataattttg gttcttcgat taaataccca acattatcac tgtttataat attacctgaa
    61681 gtcggttgat tattttgaac aagaattttc atcaacgtac tcttaccaac tccatttctc
    61741 cctactagac caacaatttc acccttgtta agtgcaaaat ttatatcttt gagaatgatt
    61801 gaatgaccat aatgcttact tacatttata acttacattt tttattcctc cattaatatt
    61861 catggtttgc tctttgattc ttattgagtt taaaaagttg cgcctctttt taacaatatt
    61921 atatcatata tctaacttaa tgcaatatat aaatgtcatt ttgtaaaatt ttattaacaa
    61981 aaaactctct acaacaaaat aatagagagt tttctgctta ttaatttttt tcaaaatatc
    62041 taagacatcg cttctttgtt taatttgata ggctttaata cctaagctcc gactttatca
    62101 cttaaaaaat aaaaaaggac agctaatctc ttgcgcatca agggatttcg ccattcttta
    62161 atctcgttta agtgttgtat atggagcttt gcataatttt ttaaaactaa acaactacat
    62221 taagcacgaa ctgtgacgct ggttccatct tccttataaa gattgataag cccctcttta
    62281 agagctcgaa ccatgtctcc agcttgaaca agttgtggga ctttaatagt caatagttcc
    62341 attggatttg gagcgcggtc gattttattg cctttggcat catgcaaatc ttcaatatag
    62401 gtttcaaaat gacggaaacc tggaccataa aactcaactt ggtccccttc gttaatgacg
    62461 ttccgttgac gaatggttgc tgtttgtgtc gcatcatcat aagaaaccac ttcagcgaca
    62521 aacttgtact cagggatttt acgacgagca ccaaacaact gctcattttc agatggtgta
    62581 ccatagtaaa atcctgtagc cagttcacgt tgggcaacct tccacatctc gtccaccaag
    62641 tcttgtttga tagcttcaaa cttttcagga ctttcaagat aggcatccac agccgccttg
    62701 tagcagttgg ttactgttga tacatagtga atagactcca tacgtccttc gatttttaga
    62761 ctgtccacac cattttcaat catatctgag atatggtcaa tcatagacat atcaacggct
    62821 gacattgaaa attcttctgg aatctcaccc tgcaaactct tacgttcttt cccaaatggc
    62881 atatcgtaaa ggtcgtactt ccaacggcat gactgagaac atccaccacg gttggcatca
    62941 cgcatactct agacggattg ttttgacaat tctaaccttt tagactttgc ataataactg
    63001 ttaaacagtc gaaaattacc ccagttttaa caagtagtca aaataccaga taaagtaaaa
    63061 aggggctagg aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat
    63121 cttgatatta tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt
    63181 tctcctactt caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca
    63241 acctggatta aagcgagaaa aacaaaagag gcaacttaag ctttctttat attgcttata
    63301 tgttaatagt tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg
    63361 ataaggctca aaagggtgat tttctaatga atcatgacac cgataacaag cataatactt
    63421 tttacaatca tagcattgta aagcaataat atccagcttg ctatggtaat gaatgcatct
    63481 tgtttgctta tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagct
    63541 cgaactgtga cgctggttcc atcttcctta taaaaattga tgagtccttc ttttaatgca
    63601 cgaaccatgt ctcctgattg aacgggttgt gggactttaa tagtcaatag ttccattgga
    63661 tttggagcgc ggtcgatttt atttcctttg gcatcatgca aatcttcaat ataggtttca
    63721 aaatgacgga aacctggacc ataaaactca acttggtccc cttcgttaat gacgtttcgt
    63781 tgacgaatgg ttgctgtttg taccgcatca tcataagaaa ccacttcagc gacaaacttg
    63841 tactcaggaa ttttacggcg agcaccaaac aactgctcat tttcagatgg tataccgtag
    63901 tagaaacctg ttgccaattc acgttgggca accttccaca tctcgtccac caagtcttgt
    63961 ttgatagctt caaacttttc aggactttca agataggcat ccacagccgc cttgtagcag
    64021 ttggttactg ttgatacgta gtgaatagac ttcatacgtc cttcgatttt tagactgtcc
    64081 acaccatttt caatcatatc tggaatgtgg tcaatcatag acatgtcaac ggctgacatt
    64141 gaaaattctt ctggaatctc accctgcaaa ctcttacgtt ctttcccaaa tggcatatcg
    64201 taaaggtcgt atttccaacg gcatgactga gaacatccac cacggttggc atcacgcata
    64261 ctcatgtggt ttgaaagagt acaacgtcca gagtatgaaa tacacatagc tccatggaca
    64321 aaggcttcaa tttcaacatc tgtacgtttg cggatctcag ctaattcttc cattgaaacc
    64381 tcacgcgcta aaacgacacg agtcaagcct agctctttcc agaactcaag ggtttcatag
    64441 ttagtggcac tggcttgggt agaaaggtgg atttcaaggc ctggtgcttc agtcgctgca
    64501 atcataatca aggctgggtc agatacgata actgctgcaa tcccgatatc acgcagttta
    64561 cggaaccact caccagcacc agcttcattt ccttcgtgca taaccatatt agccgctaca
    64621 tagaccttgg caccatactt ggccgcaaac tgcacgcctt cttccatctg ttcgaaagta
    64681 aagtttcccg cacggctacg aagaccatag gcctgaccac cgataaagac agcatctgct
    64741 ccatactgaa cagctacctt tagcttctct aaagtccctg caggtgataa aacctcagga
    64801 cgttttaatg tttttgtcat gatttctcct atttgcaata taaaagtttg acatttttcc
    64861 ttctcatttt atagtaaata aaggataaaa tcaagcctag acggattgtt ttgacaattc
    64921 taatctttta gactttgcat aataactgtt aaacagtcga aaattacccc agttttaaca
    64981 agtagtcaaa aagtctaaaa aagtaaaaac cagtatccca agatactgac tcgtaaaaat
    65041 acataaatta gtccttagat gactactccc actctgttgc tcctataatg gaaaaggatt
    65101 gatacagtct agaatatcgc ttttttattt attattctga tataaaactg ttagaattga
    65161 ttttttgttt tatacccaaa tatgaataga gacgtagcta ataagttgaa taacatattt
    65221 ggaaaaatga gaaatagcaa tattactaga acttttagaa acaatcaata tttaaaaaga
    65281 aaaaagctca aagaatttat taaaccatgt tataatagat atagctataa ttttatttat
    65341 aacaagagga tagaaatgac cgaattagaa agaaaaaatc gaaaaattag ctaagaaata
    65401 ttctgataac ttaaacatca aagttcaaga gagagttcgt gaaatggcaa atgataataa
    65461 gagccattat ttgatataca gagttttagg tatttcattt gaagaaggag aaaatatcga
    65521 tttgtatcaa aataaaggtc gttttttata caaatatgct ggttcatttt tagaagaagc
    65581 tgcagtacta tcctttaacg aaaaatttgg tacagaaaat acttaaaaag ttaacattcc
    65641 taattctgaa aatacaaaac ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca
    65701 cgcatacgaa ataaaatggt gggatgcaac tacagatgga gaccatataa ctaaagaaca
    65761 cactagaata aaagttattc ataacaaagg atatatacca attcggttaa tgttctacta
    65821 tccaaataga actcaagcta taaaaattca gcaaacttta gaaacattgt ataacggtat
    65881 tggagggaaa tattattatg gagattctgc ctgggaacat ttaagagcag tgaccggtat
    65941 tgatttactt agtattctaa cagatattgc aaataaaaaa acaggggtaa aatcaaaatg
    66001 acagtattaa aaggagataa cttagaaata ttaaaaacta ttgaatcctc aagtattgat
    66061 ttaatctata tggaccctcc tttctttaca cagaaaaccc aaaaattatc taataacaaa
    66121 aatattatgt attcattcga agatacgtgg acttcgattg aggattacaa agaatttttg
    66181 tctgtaagat tagaagaatg caaaagagtg ctaaaaaata gtggcagtat tttcgttcat
    66241 tgtgataaaa ttgcaaatca tcatattaga ttaattttag ataatatctt tggagcagat
    66301 atgtttcaaa gcgaaattat atggaactat aaacggtggt ctaattcaaa aaagggatta
    66361 ttgaacaatc atcaaaacat ttacttttat tcaaagtcaa aagattttaa atttaataca
    66421 atttttacag agtattcttc tactacaaat atcgaccaaa tactagtgga acgaaaacga
    66481 gatggaaact ctaaaactat atataaggtt gataataatg gtaactatat tctagcaaaa
    66541 gagaaaaatg gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct
    66601 aaagaaagag taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag
    66661 attgctactg ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta
    66721 gtagcctcca agattttgaa tagaaattat atggggattg atttatctga ggaagctatc
    66781 aatataactc agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa
    66841 ggaatcgaag catatagaac caaaactgag gaagaggaaa acattcttaa attattacag
    66901 gcaaaaattg ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa
    66961 aaaccgatac ctataaaaat tcaaaaaaat aatgaatgtc tgaatgagag tatctcttta
    67021 ttacagaatg ctataaactc caaaaaactt gattttggag tagttataaa aactcattca
    67081 gataatttat tatttgattt tgatacgatt cctgaaaata taatagtagt tgaccatttt
    67141 gaacttacaa tcgaaaaatg gttaagtaaa agtcaacagt tactatagtt tgcaaattat
    67201 ttacagaaag aacaaaaaat gctctgaaac actgatttca aggcattttt tgttagttta
    67261 aaattactcc cattcttctt ttccaaacgt acaatatatc caaaaccatt caaaatacta
    67321 gattctattt tttataatat cactaaatcc acctaattat aggacgtttt cagattttta
    67381 gtcccgtccc agtcccagta ccggagaaat attgttttaa tataatatct ctttttgtct
    67441 tctaagctct taaaagcaaa agaacaagta aagagtcaag acaaggataa aaagtccata
    67501 ttagggcaaa taaaaagctt taagacagat gacaaatcta agtcaaataa gaaagaccat
    67561 agcaaaggtg cagagagata aatattggcg gtcttcggac tgcctttatt tttttatcca
    67621 tttttcaaat caaatttatt cagactatat atgcacatat acacttaaat tcatataaaa
    67681 acatggcttg taaaaaatta ctttaatcac aataatcgca tttaaaattg tgatgtttgc
    67741 aagctaaatt acggacttca cttggaagtt ttcccttgta tcttttataa tagatagaaa
    67801 atttgctggc agatgaatat ccaacagatt ctgctatctc ttttataggt agttcagtgt
    67861 ttaaaagaag agtttcagct acattcattc tttttctttg agtgtactct gtaatgcttt
    67921 gacaatattt ttccttaaat aaatttttta atttagtacc actcatttta gatatttttt
    67981 caagcgtgcc ttgatttaca ttcgttgcaa aatgatcatc taagaatctt gctacatctt
    68041 caagtgcttt atcatcatca atttcaattt tatatttttt tctatttaag tatgtgtcaa
    68101 ttactatact tatccattca tttgcctttg ctttaaagaa aaaatcagcg gcaggagcgt
    68161 ccatcttaca atttaatatt tccattgcca ctctttctaa ggcctttgta agtattattt
    68221 gattcggttg aagcaaggtt gaataaaaag attctggatt aatgttaata gatgctaaat
    68281 gtttttctat tagctctttt ttaaaaccaa tggaaacagc aagataacaa caattctcgt
    68341 gtaataaaaa aacaaaatca tcttttatat tatcaaaatc aaaagtacat aaagagtttg
    68401 cggtaatagt ttgatacgga ttaaactttt ctccgtttgc actgacaatg taacttgaat
    68461 aaattgaaac atagtctgac atactataag tgctattttg aactacttcc tctttgatat
    68521 aaaaatcatg tatatcgata atgaagctgc ctccttcata aaaccaatat aggccttctg
    68581 cataagttga attctctttt ttccaacaaa atgtatgacc tgcacttgaa tacttctcat
    68641 tgtttttaca ttcatctact ttcatataat cttttacaaa atcataatat gacataacac
    68701 actatccctt ttagacaata ttccaattag ccttattaat tcaaaactat tgtattagta
    68761 attataacag atgtataata gaaaagcaat gatagatatt atcaattaag cgaatttata
    68821 tctaaaaggg atattaaaga aaggagatat gcttatgaag atttacaaaa aactatttgc
    68881 ttatgtccaa gataagaaat atcttggggt tttggccata attttttctg ctatatctgc
    68941 tctacttaca gtatatggat attatttaat ctacaaattt ctagataagt taataattaa
    69001 ttcaaactta tccggtgcag agagtatagc attaaaatct gttattacac taacaagtgg
    69061 agcgatattt tattttgtct caggaatgtt ttcacatatc ttgggattta ggcttgaaac
    69121 aaatttaaga aaaaggggaa tcgatggtct ggaaaaagca agttttaggt tctttgactt
    69181 aaatccatct ggtcaaataa gaaagatcat agatgataat gcagcacaaa ctcatcaggt
    69241 ggtagcacac atgattcccg atagttctca ggcaataatc acacccgtac ttgtacttgc
    69301 acttggcttt atagtaagta taagggttgg cataattttg cttgctctta ctataattgg
    69361 tggcttaatt ttaggggcaa tgatgggcga gcaagaattt atgaagatat accaagaatc
    69421 cctatctaaa ctaagtgctg aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat
    69481 atttaaagca aatgtagagt cttttaaaag cttttataag gcgataaaag attactcaaa
    69541 gtatgcttat gattattccc tatcttgtaa aaggccttat gttttgtatc aatggttatt
    69601 ttttggactg attgcaattt taattattcc tatagtttat tttatgacta gcttagctag
    69661 cgcaaaggtg attttacttg agcttatcat gattttattt ttatcaggag ttctctttgt
    69721 ttcattcatg agaatgatgt ggtactccat gtatatttct caaggaaatt atgcagtaga
    69781 tactttagag gcgctttacg aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa
    69841 taattttaaa aactataata tagaatttga gaatgttagc tttgcttata atgataaagc
    69901 tgtcattgaa aatttatcct ttaatttaga agaaggaaag tcctacgcac ttgtcggttc
    69961 atctggatca ggcaaatcaa cagtagcaaa acttatatca ggtttttaca atgttaataa
    70021 aggaagcata aagataggcg ggatagcaat aagtgaatat tctgacgaag ccttaattaa
    70081 agccatttcc tttgtttttc aagattcaaa attattcaag aagagcattt atgataatgt
    70141 agctttagct aataaagatg cgacgaaaga tgacgttatg agagccttaa aattagcagg
    70201 atgcgattta atattagaca aattcccaga aagagaaaat acaatcatag gctcaaaagg
    70261 tgtttattta tccggtggag aaaaacaaag aattgcaatt gctagagcaa ttttaaagga
    70321 ttccaaaatt attattatgg atgaagcatc agcatctatt gacccagata acgagtttga
    70381 attgcaaaaa gcttttaaaa atcttatgaa ggataaaaca gttatcatga ttgcacacag
    70441 gctatctaca attaaagacc ttgatgaaat tattgtcatg gatagtggaa aaattataga
    70501 aagagggtct gacaaagaat taatgtcaaa agatacaagg tataagagcc tgcaagagat
    70561 gtttaacagt gcgaatgaat ggagggtttc aaatgaaaga gttttataaa aaaagatttg
    70621 ctcttacaga tggaggagca agaaatttaa gtaaagcaac actggcttca tttttcgttt
    70681 attgtataaa catgcttcct gccatattac ttatgatttt tgctcaggaa gttttggaaa
    70741 atatgggcaa aagcaatggc ttttatatag tattctcagt tttgactttg atagcaatgt
    70801 atattttgct ttctatcgaa tacgataaat tatataacac aacctatcaa gaaagtgcag
    70861 atttaagaat aaggacagcg gagaatttat caaaattacc tctatcttac ttttctaaac
    70921 atgacatttc cgacatttca caaacaatca tggctgatat tgaaggcata gagcatgcaa
    70981 tgagccactc aataccaaag gtgggcggca tggtactgtt tttcccatta atatctgtaa
    71041 tgatgctagc gggcaatgtc aagatgggtt tagctgtaat tattccatct attttaagct
    71101 ttatatttat acctttatct aaaaaatatc aggttaatgg acagaataga tattatgatg
    71161 tcttaagaaa aaactcagaa agctttcaag aaaatatcga aatgcaaatg gagattaaag
    71221 catataattt atcgaaggat attaaagatg acttatataa aaaaatggaa gatagtgaga
    71281 gagtacactt aaaggcagaa gtaactacaa ttttaacttt gtctatatct tcaatattta
    71341 gctttatatc tcttgctgtt gtgatatttg tcggcgtaaa tctaattatt aataaagaga
    71401 taaattctct ctaccttata ggatatttac tagctgctat gaagataaaa gactctttag
    71461 atgcatctaa agagggcttg atggaaatat tttatttatc gcccaaaata gaaagattaa
    71521 aagaaattca aaatcaagat ttacaagaag gcgatgacta tagcttaaaa aaatttgata
    71581 ttgatctaaa agatgttgag tttgcctaca ataaagacgc aaaagtttta aatggtgtaa
    71641 gttttaaagc taagcaggga gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa
    71701 caactatctt gaaacttata tcaagacttt atgattatga caagggacaa atcttaatcg
    71761 atggcaaaga tataaaagaa atatcaacag aatctctttt tgataaggtc tctatagttt
    71821 tccaagatgt ggttctcttt aatcaaagca ttatggaaaa tattagaatc ggaaagcaag
    71881 atgcaagtga cgaagaggtt aaaagagcag caaaacttgc aaattgcaca gattttatag
    71941 aaaaaatgga taaaggtttc gatacagtta ttggtgagaa cggagctgag ctatcaggag
    72001 gagaaagaca aagattatca atagccagag ccttcttaaa agatgcgccg atattgatct
    72061 tagatgagat aacagcaagc cttgatgtta acaacgagaa aaagattcaa gagtctttaa
    72121 ataatttagt taaagataaa actgttgtaa tcatttcaca tagaatgaaa tccatagaaa
    72181 atgcagacaa gatagtagtt cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag
    72241 agcttttaca aaaatcaaaa atttacaaaa atttaataga aaagacaaaa atggcagaag
    72301 aatttattta ttaggaggac tacaatggat aataaaaaat taaaagtaaa agatttagta
    72361 agtatcggtg tttttggcgt aatttatttt gccttcatgt ttggagttgg tatgatgggc
    72421 ttgattccaa tattgttctt aatatacccg acagtattag ccatagttgc aggaactgtt
    72481 gttatgttat ttatggctaa ggttcaaaag ccatgggcac tatttatatt tggtatgata
    72541 tcaccacttg tgatgtttgc agctggtcat acctacgtag ttgtggtttt atcacttata
    72601 gtaatgataa tagcagaatt aattagaaag attggtaatt ataattcatt taaatacaat
    72661 atgctttctt atgcaatctt cagcacatgg atatgtagct ctttaatgca aatgctttta
    72721 gcaaaagaaa aatatatgga gtggtctttg atgacgatgg gaaaagatta tgttgatgta
    72781 ttagaaaagt taataactta tcctcacatg gctttagtag ccttaggtgc tttcttagga
    72841 ggaattcttg gagcatatat aggcaaggct ctattgaaaa aacactttga aaaagcaggc
    72901 attgtataat gtctactttt tcttcaaatg ctccctttaa tcccaatccg atctctaaga
    72961 tattagtcgt atttatcaca ggcttaactg ttatgcatag cataaacatc cgttttgagc
    73021 tggcaattgt ttgtcttatt ggtattttgc tttatttgaa tggatacaaa aaaacacttt
    73081 tcaaatggat tatattgtgt gggatacttt actccttgcc taattttatg gtgttatctg
    73141 aattaaaccc tatagttaag atgtttttga gtatacctat tgttattaga atgtttattt
    73201 taccatttat ggcagcaagc tttatgataa agacctcgga tgtaggcgca ataatttcat
    73261 cgatggataa gcttaagatt tcaaagaatg tatccatacc tattgcggtt atgtttagat
    73321 tcttcccatc ttttaaggag gagaagaaaa acatcaaaat ggctatgaga gtaagaggga
    73381 taagttttaa aaacccagtc aaatatcttg aatatgtttc tatgccacta ctcattatat
    73441 catctaatat atcagatgac attgcaaaag cggcagaaac aaaggcaata gaaaatccaa
    73501 ttgccaagac cagatacatt cgcgtaaaga tacagctaat tgattttgtt tatgttttag
    73561 cggttgctgg acttattgtg ggaggcttaa tatggttgaa ataaaaaatt taagtcttga
    73621 ttatggtgaa gagcatatat tagatgatat atcactatcc atagccgagg gagagtgcgt
    73681 gctatttaca ggaaaaagtg gaaatggtaa gtcatcttta ataaattcaa tcaatggact
    73741 agctgtaagg tatgataacg caaagacaaa gggcgaaata attattgatg gtaagaatat
    73801 aaaaaatttg gaactttatc aaatctcaat gcttgtttca actgtttttc aaaatcctaa
    73861 gacatatttt tttaatgtca atacgacatt agaattatta ttttatttgg aaaatatcgg
    73921 tcttgcaaga gaagagatgg acaggcgttt gaaggatatg cttaagatat tcccgataaa
    73981 aaatcttttg aacagaaata tatttaatct atccggcggt gaaaaacaaa ttctttgcat
    74041 tgcagcttct tatatagcag gtacaaagat tatagttatg gatgagcctt catcgaattt
    74101 agatattaaa agcataaatg ttttggcaaa gatgctaaag atattaaaag agaaaggcat
    74161 aagcataatt gttgcagagc atagaattta ttatttgatg gacatagttg accgtgtatt
    74221 tttaatagat aaaggaaagc ttaaaaaaac ttatactaga agtgaatttt taaagctaga
    74281 taaaaatgaa ttaaatgctt taagtttaag agataaagaa ttaagtaaat taaaagttcc
    74341 ttatttaaaa gaaggtggag agtatcagat aaaaaatctt agctacaaat ttactgatga
    74401 tgagtgttta agcttaaaag atatttcatt caagcttggg aaaatttatg gcataatagg
    74461 atccaacgga cgaggaaaat caacgctttt aagatgttta ataggtcttg agaaaaaatc
    74521 aaaagaagaa atttatttta agggagagaa gctatctaaa aaagaaagac tcaaaaactc
    74581 ttcacttgtt atgcaagatg taaatcatca attattcaca gatgaagtat tcaacgagct
    74641 tagattagga gtaaagaatt ttgatgaaga aaaggcgaaa atcattttaa aagatttagg
    74701 cctggacgaa tttattgaaa ggcatccgat gagtttatca ggagggcaaa agcaaaggct
    74761 tgcaatagca tctgttatgt gcaagaattc tccatttatc ttttttgacg aaccttcaag
    74821 tggtatggat tattccaata tgataaaaat atctgaactg attaataagt ataaaaccat
    74881 ggataaaata atttttattg tttcccatga tatagaattt ttaaatgaag tggcagatga
    74941 aatttttgaa ttgtaaaata gagtctgtta aacatgtcta tagaactagt aaattgtcta
    75001 aaaatttaaa agatactaac acatattgat atttatagaa aattaacttc aggattttta
    75061 cagtatttat aaactttata atatgtattt atagtattaa taatttccat atctttaggg
    75121 aaattattta tttacttacc ataattaaag agatgagaga taaatatcgg cagtcttcgg
    75181 actgccttta tttttttact taatttaatg cagtaaatca tacgattgaa aggaatctgc
    75241 gttatatgct ataattaggt agttaatcta tacatttaga aaggtaaaat atagaattgg
    75301 agaatgatat gggattttca tataataaat tgtaaccgcc caataacgaa gtctattgaa
    75361 aaatctccag attagtgaac tcacggatag ttcctaatct ggagatttct tatttgcact
    75421 tttcttgtac aactttagtc cacggtaaat aggcctctaa aacctctttg tttacgagag
    75481 tttccacgtt tggaagacat tctagaagat aggatagata tttctcacta tttataatgg
    75541 attgaaataa gatatgaaca aatcgattag gaaaggaaaa ttgatttata gaaatgtttt
    75601 agcagtcgat gcgtactgtt atagattcaa cgcactataa ttgatgacgt ttagctgttt
    75661 ccaacaaact cataataata gctcttgctt tagctccttc aaaactttga gaaaataacc
    75721 accctcgctt ttttaaactg agcttaggct aaaagagtcc actggactct tttactccgt
    75781 cccataacca atgatttaat ggcgcattca gctagattat tggaaaggac cagatgtccg
    75841 tctttcaaaa tagtcttaaa ggtttcttta tacttgaggc tatacttgag gctgtattca
    75901 attgcccttc ctagttttga acccgataaa actgactgac gccggcacca agcaaagaaa
    75961 tcttccatta ggggttggag atgttcttga cgtttctgta gtcgttcatc agctggcaaa
    76021 gcctcccagt ttctttccaa ggaaaataac tgattacaat aagctaaacc tttagctcct
    76081 aaggatgatt tattcgcttg cttgggggtc gcttcaaaaa acttccttct cacatgtacc
    76141 caacatccaa caagttcagc ttcttccagt tgacaataag cttctagcgg ttcgcagttt
    76201 accaagctta gcgtcgcctt gctcctaaac cttggactgc tatcgcatag gcagaactag
    76261 aggactaaag tcctaagtta ctgccgcaac atatcacaat gcacatagcc agaataatct
    76321 cctaggaatt cttgcactac cgaaccactc cgacgctgat catggtggta cagcgtgatt
    76381 gcttgattct cagctttccc agacaaaaag gtccaatagt aggtcagatg gctatcattc
    76441 tctagaaccc gataggaggt ttcatctgca tgaagtaagg gctgaatcaa tagtctcgtt
    76501 ataaaggggc tttaggaata ggagctttta caattttatc acttggatta ttcttactgc
    76561 atgtttggca tttgtaagcg tgttggatat gatccactct ttttaattgc gcaggaataa
    76621 agaccaattc ttgtcgttga aggctcgctc caatctcttt taaatcgtcc tgacaatcag
    76681 ggcaaatgct ctcttctact tgatgatgaa cttcttctga atcaaattgg gcaagaatag
    76741 cttgacgttt ccctttagat ttcttacgtt tgtaggtaat ttcctctgtt tcaactggga
    76801 acatctccat ctttctcaga tggagactct tcctcaaaaa ggttgagttg tccaaaaggg
    76861 caaacacttt tctcagagga ttttccagag agcttttgcg ttagataagc cacttgttca
    76921 cacagaaggg aaagttcatt agtgagacta tcaattatag cactctgttg ttgaatgatt
    76981 ttcaatcttc tcccatagac tttcctcctt atttcctaac tttattatat agtgtattga
    77041 atctataaca gtacaccttg actgctaaaa tatttctata aattaatttg actttcctga
    77101 tagagatgtt catatcttat ttcaattcac tatactaaaa agaaagtcct catttcaata
    77161 gaaatcacga ctttctgata aatttatttt gggagtgata gaaaagccct tcataagcca
    77221 atctacttgt tcaggtgtga gagctttgac atccttttct gtactgggcc aagtcagtct
    77281 gccgttctca aagcgtttat atagtagcca aaatccttga ccatcccagt aaagggcttt
    77341 aaagcggtct ttacgtccac cacaaaagag aaaaacttga ccggagaaag gatccaattc
    77401 aaagtgggtt ttaaccagat aagccagtga atcgattcct tgtctcatat cagtcttccc
    77461 acacacgaga tagacctgcc ctaggctaga tagatgaatt gtcatagagc aacaccttat
    77521 ccaaaagctg ttctaccatt tcgagattga gagattgaaa aaaacttact tcaagcttgc
    77581 caatacgaat ttaaagcaga atatcatttc tctttttaga atcaaaagga cgagattgtg
    77641 gaatctctac aggaacaata ggttgtggca ttaaaatatc ctccaatagt tttactttac
    77701 taatagtata caggaggaac tccatgaatg atagatacct tgttatgacg cgcttactat
    77761 attagaaagt tggctctcta attaaattaa ttctcattat atatatcaaa agaccgcagt
    77821 ttgaaaacta cggtctaatt ttttgtccaa atgtaaatca cttggaacta ttattcaatt
    77881 tattcttttt agtaaatgtt cccgttttaa tcccagttac agtttttaat cctctgtaac
    77941 cgttgatttt acaaagcttt taattttttt gcgattactc ccactcaact gttgcaggtg
    78001 gtttacttgt aatatcgtag acgatacggt taacatgatc cacttcattt acgatacgta
    78061 ctgagatttt ttgaagtact tcccatggaa ttttggcaaa atcagcagtc ataccatcga
    78121 tagaagtgat agcacggatt gcaatcgtgt agtcatacgt acgaccgtca cccataacac
    78181 cgactgaacg aacgcctgtg ttaacagtga agtattgcca aatatcgcgg tcaagtccag
    78241 ctttagcgat ttcttcacga agaatagcgt ctgattcacg aacggtttca agtttctctt
    78301 cagtgatttc acccatgaca cggatagcaa gtcctggtcc tgggaatggt tggcgccata
    78361 cgatatggtc tggcatacca agctctgtac caagagcacg aacttcatcc ttgtaaagag
    78421 tattgagtgg ttcaatcaat tcaaactgca tatcttctgg aagaccacct acgttgtggt
    78481 gtgacttgat agtttgagct gtatccgtac cagactcgat aacatctgta tataaagtac
    78541 cttgagcaag gaatttcaca tctttgagct tgcttgcttc gtcatcgaat acatagacaa
    78601 actcgttacc gatgatttta cgtttttgtt caggatcaga aacgccagca agtttgtcaa
    78661 ggaaacgttt agcagcgtct gctttgacga tattcaaacc aaacttacca ccgagcatgt
    78721 ccataacttg atcagcttcg cctttacgaa gaagaccgtg gtctacgaag atacagatca
    78781 attgatcgcc aatcgctttt tggagaagaa ccccaacgac agatgagtca acaccacctg
    78841 atagaccaag aaggacacgt ttatcaccga cggtttcacg aatttttttg atctgcatgt
    78901 caatgaaatt atccattgac cagtcacctt tagccttaca aatgttaagg gcaaagttac
    78961 gaaggatatc atttccgtat acagaatgac gaacttctgg gtggaattgg ataccgtaaa
    79021 tgtgtttatc tgggttttcg atggctgcgt ataggcagtc agctgatgta cctgtacgaa
    79081 caaagtcagc aggaatctca gtaaccgcat caccatggct catcaaaaca gtctgttcat
    79141 caggtgttga ttcaaaaagc gctgatggtg tgtgagttag ggttgattga ccgtattcac
    79201 gatttccagc atcacctgca ggaacaactt ttcctccaag tttatgggtc aataactgca
    79261 taccataaca gattcccaaa attggaattc cgagttcgaa gatttctggg tcaatatcaa
    79321 atgaaccatc ttcatataca gaatttggac cacctgatag aataattcct acaggattga
    79381 cttcacgaac ttcagcagct gaaattttat ggctttttag ttctgaaaaa acaccaatct
    79441 cacggatacg gcgtgaaatc agctggttgt actggctacc atagtccaat acgatgattt
    79501 tttctacatc ttgcaaatca gttgaaatgt tgctcatctt tttcctttct caaaagaaat
    79561 atcttttctc aatattctat cacaaataag ggcgaattac caactaaaca aggcgaagtt
    79621 tgactttttc tagtttattg gggtacaata gagaaaagat agaaatgaag tgaaaaatat
    79681 gctacctgct tatatgaaaa tccatgatca gataaaaaag gatattgacg agcaccgttg
    79741 ggctattggt gagaggcttc ccagtgaaag agatttagct gagcagtttg cggtcagtcg
    79801 catgaccctc cgccaagccg tatctctatt agtcgaagaa ggcgtcttag agcgccgtgt
    79861 aggaagcggc acctttgttt ccagtactcg agtacaagaa aagatgcgag ggacaaccag
    79921 ttttactgaa attgtcaaat cccaaggtaa agttccctct agccagctca tttcctacaa
    79981 aaaaaccatt cccaatgagc aagaagttgc caagctagga atttttccaa cggacaatat
    80041 tatccgaatg gagcgggtcc gctatgccga ccaagttccc ctagtttatg aagttgcttc
    80101 tattcctgaa aaattcatta aggactttaa aaaagaagaa atcaccagtc atttcttcca
    80161 aaccttgcaa aaacatggct atcgtatcgg caaatctcaa cagaccatct atgctcgcct
    80221 tgctaaagaa aagattgccc actatttgga agttgaaaaa ggacatgcta ttcttggatt
    80281 gacccaggtt tcctacctag aagatggtac tgcttttgaa tacgtaaaaa gtcaatatgt
    80341 aggcgaacgc tttgaatttt atcttgaaaa taattagatt accacgcaaa aactctctgt
    80401 cacggacaaa gagtcttttt tatttttcta agaataaatc tttcaaagaa atcaaagtta
    80461 cagcaaacaa tatcattgcc ataccaataa aatcaatggg ataaaattgt tcattcatta
    80521 ttaagaaggc aaagaaaacc gccgatattg gctcaattga agccaacaag cttgacttga
    80581 ccggtcctat cagactggct cctttaagga aagctgtata ggcaaagaca gtcccgataa
    80641 ggataatgcc tgcaaacgca aggagaaaat caagactagt cgggatatcg gcctgtagaa
    80701 cccctgtaaa aggaagggcg accaaacctg ctatgaccat ccccacacca atgaccaagc
    80761 tgctccccca ctttttaatc aaggctatgg gtaaaatgat atacaaagca taagtcaagg
    80821 cagaaaagag accccagaac aggccagcag gtgtcatgga taactggtcc aactgcccat
    80881 gtgttgcgat caggaaggtt cctccgatgg cgaatatgat ggaaactatc tctcccagtg
    80941 tcggtgccac cctatccttg atacagctat aaattaaaat tccgacagga caaacatact
    81001 gaagcaccgt cgctgttccc gcattggtct cctgaatagc agacagatag gcgaattggt
    81061 tgagaaaaag accaatcaga gcaaaaataa gaagagacag caaactcttt ctatccttta
    81121 aaaagaccag tattttatcc tttgcagtag cataagccaa gagcatgaga attccaccag
    81181 cgattaaaag acgcaagttg gtcaagacca gagccgaaat tccgtgtgcc attaggtatt
    81241 ggccactcgt tcctgacaac ccccaagcaa taccagccac aactgttagt aaagtccctt
    81301 ttaaactatt tgacatgtct ctccttactc ttctttgcga atcaagttca tcacttgatt
    81361 gcggtctaat atccattgag ctctctcgtc cttttcatag gtacgattcg ataggaaaat
    81421 agtggcttct tgcttctgac gattccacat gataaaggta cctgtatagc ccgtatggtc
    81481 tagccaatct ccttccaaat tccatgctaa agaacgttcc ttgtcatcca aaggagaaaa
    81541 attttgattt aagtctcttg caaaatcatc tgctaaatag tgttctaaaa agatttgtaa
    81601 atcctttata gtcgaaaata aaccagcact cccagcatgt ctacccagga gacgagcctt
    81661 gggatcatgc actatgcctg cctctacacc tctaactgtt ggaacagcaa gctcaactgg
    81721 cccaaacttg gtttccgtca ttccccaagg tttccagact tgatccttta aaatcacatc
    81781 caaatcttga ttaaaaattc tttccaaaat aaagcccaac agcaaaaaat ggacatccga
    81841 ataaagaaag gctggctgac ttcgtctgtt gagatgaaac atcgcttcct ttaattcagg
    81901 ggctgttaaa agatcacgat taggaataaa aggatcaagg tctgttgcat gagtcaagag
    81961 ctggcgaata gtgatgtctg gataatcact ctcaggtaaa aaatctatta ccagtctatc
    82021 aatatctaat tgacctattt cccacaagaa ggtacaaact gtgccaaccc caacaacctt
    82081 gctgacacta gctaggtcat aaactagtcc tgcctcagtc tgcaagccat gctctgggtc
    82141 actctggcct aaatagaact ctgtccattg attgtcctta aaatacgcaa aagaggctcc
    82201 gggataaatt cctgcctcga tttgttcttc tattttttta ataatcttgg tccacttcat
    82261 acttcttcaa accacaattc aacattattt ctatctttac aaaggaagaa tttttcagac
    82321 ttaggaataa aatattcagt agactcaaac ttctggcgaa gacttgctat gtctaattca
    82381 ttgaccaaga acttgagcat agataagtcc caggtaaccg tattgtccac agtcaaatcc
    82441 tgcccctgag ctggaataaa atcaagggat gccccaattt cagatgattc caagaaactt
    82501 tcgatatcag ttgggagatg taattccata gaaatctcaa atttacttaa agaaattgat
    82561 gccaaatctg tttgaaattc aggcttttct cctacttcta ctagacttgc tatgtcatct
    82621 tccgcatgaa tcaaaatcaa atcatcttct ggtgagaaaa tttcaaaagc gtagccattt
    82681 tgacctttat ataatcgatg aatcgaatct gttttagata agattccttc aatttctaag
    82741 ggattttcca ccttgacaat caatctagct agtttttttc ttccctctac cttacgagta
    82801 cgcatactgg gagcttcttc taaaaccagc ttttcaagac ccgtttggtc acctagtgac
    82861 agaaaggccg attcttctaa caaggccttc attccaaggg tttcaatata aaatgtttca
    82921 tttaattttc tattattagc ttttaaagta ggaataatcc gtacaatctg atttacattc
    82981 ataaattcct ccgtcacttt ttattttaaa ggattttaga attttttaca agatattatg
    83041 ctcaaattta acattattta gctatttagt aaagatagtc tttcaaggat tttgacaaag
    83101 cctgataacc agcaatactg aggtgcagtc catcagttgt atattctttt ttgagttggc
    83161 ctgcttggtc tgtcaaacaa tcaaatactg gcacaaattc cacctgcata taggcagatg
    83221 caagctcttg ataggcttga ttccagttct gaattttttc attcgagcgg atatagactg
    83281 cctgctggta ctcctctctc tcattgacag gcaaaatgga aagcaattta atctctgtca
    83341 atggataatc gcgagcaacg gattgaatga tagcttcgag attattgaga gcctcattca
    83401 caggaacatc ctttccgata tcatttgtcc caatcagaag aaaaatttta tctactgctc
    83461 caccatatag atgagcatca aggttctcta gtaacagtcc tgtctgatag ccacgaattc
    83521 ctcgattgac aatcgtcttt gaagtcccaa atagctcctg tagaggataa tactcgacaa
    83581 tggaatcccc aataaaaaga atgtttggtt ctacaacaga aatgtgattt aggtgacgat
    83641 acttagtttg aattttttct tgttccttta ggagccaatt ttctaataac tgtactgcca
    83701 cttcattctc ctttttctaa ccagttttcc aagacttgat aaactcctcc ttggctgttg
    83761 gctggtgcta gagcagtcgc cacagctttg gctttctcat cagcattttc catcgcatag
    83821 gcaattccag ccatttcaag catttcaaca tcattttcac tatcaccaaa agccatgatt
    83881 tcttgggatt tcaagtccca gcgcttgagt aattcctcca agccccatgc tttatgaatc
    83941 ccagcttgga ggatatcaat gcaaccatag ccactggata cagctcggac acggccatca
    84001 aagagagcat tgatttcttc caaaaccgaa ctcaaacgtt cctcaccaac aaccatgctc
    84061 atcttgagca caccaccaaa gaggtcagat gttaattcat ccacaaattg catccgttgg
    84121 tagaattttt caatcatttc tggagtcata aaactttcaa gatctgtaaa aatcgtacct
    84181 tccttgacaa aatcaccctt catccccgtt acaacaaact ggtcctgaca cgctcgaccc
    84241 ttgaaatgag tcaaagcctt gttgacaatg gcgtcatccc atgtctgagc ctgaatcaat
    84301 tcattgtttt caaaaatacg agcgccatta gcaacaacca gaaccactcg atccaccaag
    84361 ggactcagta gttgtctcat gcggtgaatt tcattgcccg tcgcaatgac aaaacgaatg
    84421 cccctttgat ccaactgatc taaaatcttt tccaatcgtg ggagatcaag ctgacctcta
    84481 gcatccagca aggtcccatc catatctgtc gcaattacct taatcatcat ttactttcct
    84541 ctggattcaa gctaatacca cttcaatccc acatgttcat tcatttcttt ataggctgta
    84601 tcaattcgtt ccttagtcgc ttcatctaac tggtcacgat gactgccatc ctctataaaa
    84661 tcttccaaaa tataagtttg gtaatgatac aagggatatc cttctggtga aaaggttccc
    84721 tttggtgttc gattgaccca agtaggatga gctttagctg ttccgatagt tgtttttcca
    84781 tccttcttct tgatggtgac atccatgaga acaccacgtt cagtccactt agcattctct
    84841 tcatctccca tagattcaat tcgttgattg gaaatgaagt tccccattta atagacaatg
    84901 agctttttat ctccatcttt ttccaccgtt tcagatggtt caacaacgtg aggatgccct
    84961 ccaaagataa tatccgctcc ccaatcaatc atcttgtgat aaagagcttt ttgttcttca
    85021 gttggttcca atcgatactc aacacccatc tgaggcatga taatggtgat atctgcttcc
    85081 ttctctgccc gttcaacttc agcctttatc ttatcttcgt ttaaatctga aagataacga
    85141 ttatagtctt cctgagaaat atactgctca attccattga aaccatagga ataggctaac
    85201 aatgcaacct tgatagcatt cacttcctta atgaccagcg gagcctgagc acgtggttcg
    85261 tgcgtataaa ctccgattgg agtgattcca gctttctcaa taatatcggc cattgaaata
    85321 actccctcaa tttgcgaatc caaaatatga ttatgagcta aatccagcac atgataacct
    85381 gcctccttaa tagcatccat aacttcaaca ggagcattaa agagaagata acccgctaaa
    85441 taatgatcct tattaatggt tccttcaaaa tcaccaatag ctaaatctgc ttgcttgagc
    85501 caaggagtca catactcaaa attttcatga aagtcatagg taccgtcttc ttttttagct
    85561 gaaaagaaaa gtccatcgtg gtagagcaaa tccccgtggg ccataattct ggcagttttt
    85621 tcctcttcct actcctgaga cttttgctta gtcccctctt gagaaatagt atctcgtttt
    85681 tgactagtca agggattcct tggaagcttt caaacaacaa gaccaagccc attgataaac
    85741 caactgctag caagagtatc gccacaaatc ccttattgct ccacttgcga taactcctaa
    85801 aaagtttacc aagcccttca taaaacgaaa agctgaacca ccctgatttc gattttgtct
    85861 tctttgtatc ttcgttctcc ctactttctt atgcaagcct tttcttttta ttatatcaca
    85921 gataagtatt tctttcacaa ttgaattgaa cttcctatct attttctata aatcctaaat
    85981 gccataatgc tttcaattct tgtcattttg tgatatcatg tagaggaaat gaactaatcc
    86041 acagtggctt attccaagta taccacttgg gctttggcag tagctaactg cactaaacat
    86101 aatataagga gagaaaatgt ctgcaataga acgtattaca aaagctgctc acttaattga
    86161 tatgaacgat attatccgtg aagggaatcc tactctacgc acggttgctg aggaagtcac
    86221 tttcccccta tctgaccagg aaatcatcct aggcgaaaag atgatgcaat tccttaaaca
    86281 ttcccaagat cctgtcatgg ctgaaaaaat gggactccgc ggtggtgttg gactggctgc
    86341 tccccagtta gatatctcaa aacgcattat cgctgttttg gtacctaata ttgttgaaga
    86401 aggcgaaact ccacaggaag cctacgattt ggaagccatt atgtacaatc caaaaatcgt
    86461 ctctcactct gttcaagatg ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg
    86521 taacgtgcct ggctatgttg ttcgccatgc ccgcgttact gttgactact ttgacaaaga
    86581 tggagaaaaa caccgtatca aactcaaagg ctacaactcc attgttgttc agcatgaaat
    86641 tgaccacatt aacggtatca tgttttacga tcgcatcaat gaaaaagacc catttgcagt
    86701 taaagatggt ttactgattc ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt
    86761 tataatagag gcatgaaaac aaatgatatt gtctatggtg tccacgctgt taccgaagcc
    86821 ctccttgcaa atacaggaaa caaactctac ctccaagaag atctccgagg taagaatgtt
    86881 gagaaagtca aggaactagc tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa
    86941 tctctctctg agattactga aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa
    87001 tttgcctata gcgagctaga ttacatcctt gcaaaaacac gccaagaaga aaatccactt
    87061 ctattgattc tagatggtct aaccgatccc cataatctgg gttctatctt gcgaacagcc
    87121 gatgcgacca atgtttcagg tgtcatcatt cccaagcacc gtactgtcgg agtaactcct
    87181 gtcgttgcca aaacagccac aggtgctatt gaacacgttc caattgcccg agtgaccaac
    87241 ctcagtcaaa ccttagataa acttaaggat gaaggtttct ggacctttgg aacggatatg
    87301 aacggtactc cttgccacaa gtggaataca aaagggaaaa tcgccctcat cattggaaat
    87361 gaaggaaaag gtatctctag caacatcaaa aaacaggtcg atgaaatgat taccattccg
    87421 atgaatggac atgttcaaag ccttaatgcc agtgttgctg cggccattct catgtacgaa
    87481 gttttccgaa atagactata aaaaagtttc cagtcatctg attggaaact tttttatgat
    87541 taactatgtt ctgtaatgaa tttataggct tcttgaccag cgatagctcc atctccaacc
    87601 gctgttgtta cttggcgaag gtctttcaag cgaacatctc caactgcaaa gataccgtcg
    87661 actgcagttt tcatgtggtt atctgtcaca atccatcctg cctgatcttg gatattcaat
    87721 tctttaacaa aatcgctaag agggtccaaa ccaacataga taaagacacc accgaaggct
    87781 tgttctgtca cttgacctgt tttcacattt tcaaatacga ctgattctac tcggttttca
    87841 cccttgattt cccttactac agaatcccag ataaagctga ttttttcatt cgcaaaggcg
    87901 cgatcttgta aaaccttttg ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc
    87961 ttagcaaaac gagtcaagaa gagggcttct tcaacagctg aatctccacc accaactacc
    88021 aataaatctt ggtcacggaa gaaagcacca tcacacacag cacagtaaga aacaccacga
    88081 ctgttcagtt cttcttctcc aggcactccc aaaggacggt gtttagaacc agttgctacg
    88141 ataactgtac gtgtttcata tgtttggtca tcagtcatca ctttcttaaa atcaccatgg
    88201 tcttcgacat tttcaacata accataaatg tgctcaacac caagattttc aagtggttca
    88261 aacatctttt cagccaattc aggtccacta atattagcgt atcctgggta attttcgata
    88321 tcagatgtat tattcatctg accacctggc agaccacctt caatcaaagc tacttttaga
    88381 ttgcttcgag cagcatacaa ggccgcagtc atccctgcag gtccagcacc gataataata
    88441 gtatcgtaca tatagattcc ttctttcttg ttgtaactat ctttattcta actctttctt
    88501 gtcaatcacg caaggattat gccttgaaaa caagaattaa actcataacc gcaaaggata
    88561 atactgggac aaccaagact ccaatcataa tcatatcata gagatgggct tggcgagccc
    88621 tggctgtctt atcaactccc gacatggctc tcagaccaat ccaaatccct aaaaaaatca
    88681 gaacaaggat ggtggtcaag atcaaactct cgaaatataa agaaaatagt tgcagtagca
    88741 tgatttctct catttctatc ttttttaaag agtaaactca gctagtccaa ctaactgagt
    88801 tttcctttat ctattatatc aaatataagt ccgtttgtaa ctagcgaaga attcttttgt
    88861 ccgctcttct ttaggggtgt ggataatctc atccggagtt ccagactcga tgattttccc
    88921 cttatctaag aagagaattt tatccgcaac ttgggctaca aaggacatgt catgactgac
    88981 caaaatcatg gtctgacctg acttagcagc atctgcaata gacttttcta cttcaccgac
    89041 caattctggg tcaagggctg aagttggttc gtctaagagc aaaacatctg gtttcatagc
    89101 aagcgcacgc gctagggcaa cccgttgctt ctgtccacct gataaatggc gaggataatg
    89161 gttttcacgg tccgaaagcc caaccttagc caactcttcc ttggcaatct tagtcgcttc
    89221 ttggtcagat aatttcttga caacaaccaa gccttctttc acattatcaa gtgctgttcg
    89281 gcgttcaaat aaattaaact gttggaaaac catagacaac ttacggcgta gggcaaggat
    89341 ttcttcttga gtgattttag aaaaatcaac tgaaaaacca tcaatctgaa tagagccact
    89401 gtcaggtgtt tcaagataat tgagactgcg aagaaaggtt gattttccag ctcctgaaga
    89461 accaatcaag gctacgactt ctcctttttg aatatccaag ttcagatgat ccaagacagt
    89521 ctgtcctgaa aaggatttgc ttaaattcga aatcttaatc attaacgaag gtctcctttc
    89581 acatctgttt gcactgtatc aggtgcagaa atagccattt ttctctcgat gaaacgaccg
    89641 aggctttcaa ttccgatatt gactacccaa taaacaaggg caacggagat gaagcgttca
    89701 aaatagcgat aatcagctcc acctagaatc tgagcttggg caaagacttc cacaacaccc
    89761 gcactaaaag ctagagatgt tcccttggtc aaaccgatga gggaattaat caaggttgga
    89821 gtagctacca ccgctgcatt aggaataatc actcgtcgat aaacttgcgc tcgggtcata
    89881 cccagactgc gtgccgcctc aatctcacca ggattaactg agagaatggc tgcacgaatg
    89941 gtttcactag cataagctgc ctcattaaag gcaaaagcga caatcgcaaa agctgcagct
    90001 ggaatcgcat tgatattgag accagttccc cattgctgat tgagggcttt caaagccaaa
    90061 gggattccgt agtaggtcaa catgagttgc accaaaatcg gtgtcccttt taagaaacta
    90121 acaaagaagg cctgcaaggg atataaaatc ttgacacgat tgatcttcac aatggcaaaa
    90181 agaagcgcca aaaccaagcc aaaaagggca ccaccaattg tcaacataat tgttgttgga
    90241 agttgttgga caattctagg gattccatca aagaccgaac gtaggctaaa cagcttgcca
    90301 tccggaatca attgcatcaa gttttggtac caatctgatg ctaaaatcgt tgtaacattc
    90361 ataaaaacat cctcttctga taatgattca ttctaccatg cttctgccgt caatgaaatt
    90421 atttgctacg gtcagataca gactttgtct acctactagt ttatcatact ttgaaacagg
    90481 gaagttatat attttatcta tcaaagagat agataaaaac tatttcagtc ccagttcttc
    90541 ataagatttt cgataaccga tttgcttaac agttccattt tctactaaaa tgggccgttt
    90601 taacaacata ccgtcacttg ctagcaactc agccgcttct tggtttgaca aacttcctac
    90661 cttatctttt agccctaatt cacggtattt gataccactg gtgttgaaaa attgcttcaa
    90721 ttcaaatcct gaggtttcta gccaattcaa aatgacttct tggctaggtg tttcttccac
    90781 gatatggacg gctttatagt ccacacctaa ttgatttaat tcttgttttg cttttttaca
    90841 agttgaacat ttggggtatt cgataaattc taacatgtgc ttctccttct atttgtttat
    90901 atctttaaaa tctacgcctt catgctccaa gagccaagct ttcttttcca ctcctgcagc
    90961 atagcctgtc agacgcttgc ctgctcccaa cacacgatga caaggtacta ggatagacca
    91021 aggattgcgt cccactgctc caccaattgc ttgagcagaa gccacttgca ggtcttgagc
    91081 aatttgtcca taggtcactg tctgaccata aggaatgccc tgtaaatagt cccaaactct
    91141 cttttcaaaa ttcgttccga ttggcgccaa gagcaagttg gataaatcct gaggcttgcc
    91201 tttaaagtaa tcatctaagc aagcaataac tgggtctaaa ataggatgac taacaacttc
    91261 ttctatcgtt tcatctccta gtcccctctc aaaatgcttc tgctcctgaa cccaaattcc
    91321 atacaaataa tggtcatcag ctacaagtga tagaatacca attggtgagg agtagagtat
    91381 ttttacatac ttcttttgca ttatttcttt aatttttgat aggccaagcg ttcgccatct
    91441 actggcacct taccaacttg tttaaaacca agtttttcaa aaatatgttg cataaccttg
    91501 ttttcagcat gcgtatctga gcgaaaatca agataatcaa aaccttcaat caagccctct
    91561 aagaaggttt gagcaactcc ttttccctgc acatctgctg ccacagcaat acggtgaaag
    91621 actagatact ctgactctcc agcttgccag tttccctcat aaatagcttc ataggcctcc
    91681 tctggactct tggtcacagc agcataggct agcagttctc cctcttccaa ggctacgtag
    91741 gcttgccctg agatgatatc atcgataata acatctgcat ttggatagcc attttgccac
    91801 tggtcactac cagcatctgc taaacatttt ttggcatcct ccatcacctg catgatggca
    91861 tctacttcat ttggaaaagc taaacgaatt tccatctttt ttcctcattt ctgactagtt
    91921 tctcccatca tagcataatt taagtatttc tacaagcagt taaaacttga ctttgtgttt
    91981 ttgttatttt ataatctagt tatcaaaact atataaaaag gagttaaaaa tgaaaactac
    92041 cttttcctac ccaaaatggg cagaaattcc aaacattgac ctctatctgg accaggtttt
    92101 gctctatgtc aatcaggtct gcgcccctat ctctcctaat aaagacaagg gcctaacagc
    92161 atctatggtc aacaattatg tgaaaaatgg ttacctgaca aagcctgaca aaaaaaaata
    92221 ccaacgccaa cagattgccc gtttgattgc tatcacaacc ctcaagtctg tattttctat
    92281 tcaagaaata gcccagacac ttaatactct acaaactcaa gcaagttcag accaactcta
    92341 cgatgctttt gtggactaca tgaaccaagg aattgaccca gctaacccta ttatccaaac
    92401 cagctgccaa accgttaaac tctatcatca aactctagac ttaatcgatc atactcaaga
    92461 ggaggtaatc caatgaacac tagtcttaaa ctcagcaaac aactcagttt tggagaggag
    92521 attgctaata gcgtgaccca tgctgtgggt gcagtcatca tgcttatctt gctgcctatt
    92581 tcatccatct atagttatga agcacacgga tttttatcct ctatcggcgt ttccattttc
    92641 gtcatcagtc tctttctcat gttcctatca tccaccattt atcactctat ggcctatggt
    92701 tcgacccaca aatatgtttt gcgaatcatt gaccattcta tgatttacgt tgccattgcc
    92761 ggatcataca cgcccgttgt cttgaccttg atgaataact ggtttggcta tctgattatt
    92821 gtcatccaat ggggaacgac catctttggt attctctata aaatctttgc taaaaaggtc
    92881 aatgagaaat ttagccttgc tctttacctg attatgggct ggttggttct ggctatcatt
    92941 cctgccatta tcagtcaaac gacacccgtt ttctggagtc tcatggtaac tggcggactc
    93001 tgttatacag ttggagctgg attttatgcc aagaaaaaac cttatttcca catgatttgg
    93061 catctcttta tcctagctgc gtccgcactt caatacatcg ctattgttta ttacatgtaa
    93121 aaaagttgag aaattcaatc tcaacttttt tctttacaca tattgataaa gtactggtgc
    93181 aagcgcacat catcagtcaa ttctggatga aaagaactta ccaacatatt tttttcttgg
    93241 gctgcaacaa tttgattgtt cactgttgct aaaatttcta caccctcacc aacactactg
    93301 ataatcggac cacggataaa ggtcattgga atcttgccaa ctcccttaca ttctgcttcc
    93361 gtgtagaaac ttcctaattg gcgcccataa gcattacgct cgaccaccat atccatagtt
    93421 cctagatgac tctctttctg agaagtgatt tccttagcca gcaaaattaa gcccgcacag
    93481 gtcccaaaca ctggtaagcc agatagaatg gcttctcgga tgggaagtag catgttctgg
    93541 tcacgtaaga gcttgcccat ggttgtagac tcaccaccag gcaaaatcaa acccgacaag
    93601 tcactctgat cttgctgaaa atcatctaga tttctgagtt ctacactctc gacacctaat
    93661 tgatctagca cttttgcatg ttctgcaaag gccccttgca aggccaatat tccgattttc
    93721 atctattttc ctcgttcagc catgagaatt tggatttcat tttcattaat accaaccatg
    93781 gcttctccta aatcttcaga gatttgagct aggatttgag gattacggaa gttagtcaca
    93841 gccttaacaa tggcactcgc tcgtttaaca ggatctcctg acttgaaaat acctgaaccg
    93901 acaaagaccc cctctgcccc taattgcatc attaacgcag catctgctgg cgttgcaaca
    93961 cctccagcag cgaaatttac aactggcaat tttccatgtt catgaacata ttggaccaat
    94021 tctacaggga cttgcaaatc cttggcagca acataaagct cgtcctcacg taagttttga
    94081 atgcggcgaa tttcctgatt catcatacgc atatgacgaa cagcttggac gatatcccct
    94141 gtccctggtt ctcctttggt acgaatcatg gaagcacctt cagcgatacg acgcaaggct
    94201 tcacccaaat ccttagcacc acagacaaaa ggaacttgga attctttctt gtccacatgg
    94261 aaacggtcat cagctggaga tagaacttca ctctcgtcga tataatcaat ttcaatagcc
    94321 tctaaaatct gagcttcaac aaaatgcccg attctgacct tagccattac tggaatacta
    94381 accgcttctt ggatttcctt aatcatcttt gggtcgctca tgcgggaaac tcctccagct
    94441 gcacgaatat cagccggaat tcgttccaag gccatcacag ctgccgcacc agcagcttct
    94501 gcgatacgag cctgttcagg attctgcaca tccataataa caccaccctt gagcatctgt
    94561 gccaagtttt tatttagttc ataacgattt tcagtcattt gttttatcct catcatttgt
    94621 attggtagct accttttcat tttaagtcag aacagaatga agcacaagat aaaaaaacta
    94681 taattgtatg gggacaaatt agctaaaaac tatctgacat taacttaagg ccagatagct
    94741 cattcatttt tatttttcag ccgtaagggc agccattgtg atgtagttgt atggtttgtt
    94801 gaagtgtggc aagaagaaga ggtctgtcaa tgccaattta tcaattgtca catgctcttg
    94861 gatagcaagt gagaacatgt ggattcccat gctaattgca atatcatgtg aaaccatttg
    94921 ggcaccaaga atttcacggc tatctttgtc aaagacaatc ttaattgcta cttcatggtt
    94981 gtcatgtttc atgaattctg gtttttgaag atcgttaaag cctgtttcag ttgcgttgta
    95041 accagcagct ttcgcttttt caagagtcaa accagttgaa accatgtgaa gaccgtagat
    95101 tgagatacca tttgaacctt gaacaccgat tccttccaat tcatgtccac aagcattgta
    95161 ggcaccaacg ataccagtgc gaacagcatt tgaagcaaga gcgatatagc ttgtatcttt
    95221 acgagcattg tcataaacag tcgcacagtc accaacagcg taaacgtctg ggatagatgt
    95281 ttcttgtttc ttgtctacaa ggaaggcacc gttgcggaag agttcgatct taccacctgc
    95341 aagggctgtg tttggacgga aaccaactgc aaggataacc atatccacgt caaagctttc
    95401 tttgtcagta atcaagcgtt caactttacc gtcaccttcg attgctttaa cagtttgacc
    95461 tagagccaag cggatgttgt gatcttccaa gttcttcgcc atcatttgtg tgaagtcttt
    95521 gtcatagtaa ccgttcaaga cagtatcaac gatatcaaca aggacaactt cttttccaag
    95581 acgttcaaag gcttcagcaa gttcaacacc gatgtaacca ccaccaacaa cggcgatacg
    95641 gtcgaggtgt tggctcttgt cagaaagttt attgataact tcttcagcat tttggtacaa
    95701 tttcacgaat tgtacgtttt caagagttgc tttaaattcg cggtttcctt taacaatttc
    95761 aacaccttcg attggtggca agattggtgt agaacctgta gcgaaaatca atttttcgta
    95821 tgattctttg tgctcttttc cttcaacttc cgctgtaact actttgttat catagtcgat
    95881 tgaaagaaca ggtgagttca tgtaaacttt agcaccttta gcttccaatt tttctttatc
    95941 agaatagaac aagccttcag caccgtcaat ttgttcacca atccaaagag ccattccaca
    96001 tcctaggaaa gagatgttag agttttggtc aaatacaaca atttcgttct catttccaaa
    96061 attatccaac atggtattga tacatgctgt accagcgtgg ttagcaccga ctacaacgat
    96121 tttactcata aaaatttcct gccttcattc taaatttacc ttactagtat accatttacc
    96181 gttagcgttt acaagggggg tactattatt tcagcatttt ttatcaaaaa taattcccca
    96241 tttatcctgt tttcaagcct gatgaatttt atgagcatat ttcttgactt tttccaaatt
    96301 ttgtttgtga aaattctaac tttatggtat tataataaca tgaaaatgaa atgtaagggc
    96361 ttcaatttag atgattattt gatattacaa cttattttct ataagagaaa ggagttggta
    96421 gcttgactct tcgttcacat tctgaacggc taatggggac tactatcact atttcattag
    96481 tggatgagca agccgatatc tttctccaaa aatcctttga cttgctcaaa gaacttgaat
    96541 accgcttcaa cgccaatagt caagaatctg agttgatgga aatcaattat caagcaggaa
    96601 tagcccccgt cacggttcat ccagacctgt ttgagctgat ttcacttggg ttagagcata
    96661 gcctagcgct ctctagccac ctcaatatca gcattggtcc cttaattcaa acctggcgta
    96721 tcggtttttc agatgccaag gtcgcccagc ctcaagaaat tgaatcggtg ctgcctctaa
    96781 tcaatcctca tggtatcgag ttagattctt ctacttctac tgtgttttta aaacagaaag
    96841 gaatgaagat cgatctaggt tgtttagcca aaggatacag tgcggataag gttgcccaat
    96901 ttcttaggaa agagggggtg acttctgcct tgatcaatct gggagggaat atcctgacca
    96961 ttggaaaaaa tcaggcaaga ggggataacc catggcaaat cgggattcaa gacccagcca
    97021 atcctagggg aaatcattta atgaccatcc ctgttgtcaa taaatctgtc gtgacttcag
    97081 gcatttatga acgtcacctg accgtcgatg gacaagatta ccatcacatt tttgacagtc
    97141 aaacaggata tcctgttgaa acggaactag cgagtctaac aatcatctct gataaatcag
    97201 tcgatggcga aatctggacg actcgactct ttggagaaag acctgcttct atcctctggc
    97261 aagtcgaaag tttggagggc atcgaagtca tcctcatcga taaagaaggc cacctaagct
    97321 gttcttcagg aattcctact ctatagagac aactgtttca atggaatttt aaaattgtat
    97381 tatgtaaaaa gagaaaggaa atctcatgtt aaaacttatt gctattgttg gaacaaattc
    97441 aaaacgttct acaaaccgtc aattgcttca atacatgcaa aaacacttta ctgacaaagc
    97501 tgaaattgaa cttgttgaaa tcaaggccat tcctgtcttc aacaaaccag ctgacaagca
    97561 agtacctgct gaaatattgg aaattgctgc taaaatcgaa gaggcagatg gcgttattat
    97621 cggtactcct gagtatgatc actctattcc agctgttttg atgagcgctc ttgcttggtt
    97681 gtcttatggt atttacccac ttttgaacaa accaatcatg attacaggtg cttcttacgg
    97741 tacgcttggt tcatctcgtg cccaattgca acttcgtcaa atcttgaatg ctcctgaaat
    97801 caaggcaaat gttcttccag atgaattctt gctctcacac tctcttcaag catttaaccc
    97861 aagtggcgac ttggttgacc ttgatgttat caagaaattg gatgccatct ttgatgactt
    97921 ccgtatcttt gtaaaaatca cagaaaaatt acgtaatgca caagaattac ttcgcaaaga
    97981 tgctgaagac tttgactggg aaaatttgta agataggaga ccaaaaagaa tgaaatttgt
    98041 tggacttgtt ggatcaaact acgatcaatc atataaccgt aagctcttgg aatttatccg
    98101 tcgctacttc aaactcaaat ttgaattaga agttcttgaa attgacgaag ttccaatgtt
    98161 taaccaagat gaaaaatggg atgaaagttt ccaattacgt tatttatata acaaaattac
    98221 tcgtgcagat ggtgttatca ttgctactcc tgagcataac cacactatct cagcttcact
    98281 caaatctgta cttgaatggc tttcatacga agttcatcca tttgaaaaca agcctgttat
    98341 gattgtgggt gcatcatact atgaccaagg aacatcacgt gctcaagttc accttcgtaa
    98401 aatccttgat gctccaggtg ttaatgccta cacgcttcca ggtaacgaat tccttcttgg
    98461 taaagctaag gaagcttttg ataacaacgg aaatatcacc aacgaaggca ctgttaaatt
    98521 ccttgaaact tgcttagata actttgttaa atacgtagga gtcgtttcga aattgaaaaa
    98581 accaaaacca atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta caaccatcac
    98641 agaagttgac cctgacgatc cagaatgggt agaaaaagtt gcagcattca ctggtgctgt
    98701 ttctggtgat acctatgtca aattggacca cggtatccta acagttaacc aaattgatat
    98761 gttcttgaaa gctatgccat ttgaattgac atacgctgac gacaacaacc aattcctcta
    98821 ctacaacaac gctcaccaag atccagacac tatgttcgct aaacgtgtac cacctcaatc
    98881 aggtagccgt atgtcgactg ttcatggttc tcttccacca gcacgtatga agaacgtaga
    98941 gtgggttatc ggaacacttc gcaacggaaa ccaagaatac gtccgtacga tcgttccagg
    99001 ttctcctgca ggtgttatca acactcacaa ctaccaagca atgtactatc ctgatggatc
    99061 atacgctggt atcaatgaaa tcgtctttaa cttccaacca tggcttgact ggtacctaaa
    99121 agagactggt caacgtttgg tgggtggtag cggaccattt gctcctgctg ccggaggtca
    99181 tggagacgcc gatgctactt ctagcgcttc tgattcaggg gatgctggag gccacggtgg
    99241 tgacgcagac gctacagccg gtgcaagtta ctaatgatag tttttaggaa ctattatggt
    99301 tcctttttta gcgaaaaaag actagcaaac acaaactgct agtctctttg ttatcgtttc
    99361 atctatcttt gttaaaagaa agaatacata tactcaatga aaatcaaaga gcaaactagg
    99421 aagctagccg caggctgtac ttaagtacgg caaggtgaag ctgacgtggt ttgaatttga
    99481 ttttcgaaga gtattattat gaatttggat catcaagact acggccatgt aatccttttt
    99541 cacgttgtac ttggcgtagt ttttctggtg taacatcgtt tccttcttcg tccacaattt
    99601 tgattccttc aatgtggtga cgaacagcgc ggcgataacc ttcgatgtac tcctcacgta
    99661 gtttggcttg ttccactttt tcttctggtg ttaagccttc tgtttttttc tttttagcaa
    99721 gctcattgat acgagcaatt tttttcggat ccatttcttc tcctttgtaa taagataaag
    99781 tccgtttatc aaattttatt tagtgttaat ttggttaaaa caagcaaact tagctgcttt
    99841 cttggttagt tgtgacaaga ttgccaaacg attttgacgg acagcctgat cttcagccat
    99901 taccatagta ttttcaaaga aagcatcaat gactgggcta agcgcaaaaa gttgtttcaa
    99961 ttgctgactt gcaggtcctg ataaaatgag tgtttctact gcttctgcca aagctttttc
   100021 ttggtcattc tcaaatagtg ctgaatcaac cgtagcaacc ccttctgcct tctcggccag
   100081 gttaaaggca cgagaaagtg attcaacaga tggtttaaaa tcttcttcct tgcttacttc
   100141 tacgagagca cttgctgctt ccaacatatc tgccacaaca aagtttgaac ctgcaagaac
   100201 tgcttccttg atatcttttg gagtagagcc catcatctta tcaacacgag ccttgataaa
   100261 gtccataacc tctgctttat tttcataagt caaactgtca aatttcaatg cataaaggct
   100321 atcaatcagc tcatccatag caatgtgcca accaaaggca tccaagatac gaaccacacc
   100381 ttgagttgca cgacgaaggg cataagggtc attagaacct gatggaatca atcctactga
   100441 gaagaaactc aaaatcgtat ccaatttgtc tgcaatggct agaactgcgc cgaccttgct
   100501 ctctggaagt tctccttcag ctgatgtagg catgtagtgt tcacgaatag cagctgccac
   100561 cgctggagtt tcaccagcaa gaagggtgta tttttcaccc ataattcctt ggagttcgtc
   100621 aaattcacca accatacctg tcaacaagtc aaacttgtaa atggctgctg cacgagcaag
   100681 gtcaactgtt tcatccactg acaaactagc tttttctgcc aaaagtacag tgatttgacc
   100741 cgtacgaatc atgtgttcac gaagggaacc aatcttctca tggaaggtga cattgtttaa
   100801 tttttcaaca agatctgaaa tcaccaattt ttggtcttca cgccagaaga attctccgtc
   100861 ttccaagcgg gctaccaaga ctttttcatt tcctttgatg acatttttca aacgctctgc
   100921 gtttccgtta cgaacagaaa tgaagtttgg caagagtttt ccatcttgat cacgaacaac
   100981 aaagtaacgc tggtgttcct tcatagaagt caccaagact tcttctggaa cttcaaggta
   101041 tttagcatca aaacttccca tgaaggcagt tgggtattca accaaattca agacttcatt
   101101 cagcaaatcc gcatcaattt cgatacgtac accatgtttt gcctcaattt ccttgatttg
   101161 gtcaacaatc atttgctcac gttcacatgg atctgcgatt acaaactgct tacgaaggtc
   101221 ttcttcatag ctcaatgctg actgaatctt ggtttcttgt cccaaaaaac gatggccacg
   101281 actcacacga cttcccttga tatcaaggaa atccaagtca aactcttgct catccaagag
   101341 aacagttaaa gtgtgaacag ggcggatgta ttcaaagcta tttcccgccc agtgcatgct
   101401 gacagggaaa gtcagtgact tcaagacatc cacaatgcct ggaacaatgg cttcaactgc
   101461 ttgaccaatt tcttccttag tgacatagac atattcttca cccttgattt cacggaattc
   101521 gatatcttca acagtcaaac ctttcccacg gacaaatcct tgagctgctt tggtgaagtt
   101581 tccatcacta tctaaggcaa ttttctttgc tggacccttg aaatcttctg ttaaatcaga
   101641 ctgtttgtct gcaagaccag ttacacgaac agccaaacga cgtggtgttg agaaagtttg
   101701 aatggcttca aaagacaggc gttttccctt gaggaaggct gccatttttt cgcctagttg
   101761 tttttcactt ggcgtaacaa cataggctgg taattcttca agaccgagtt ctactaataa
   101821 gttttttgtc atgttttttc ctttacattt tcttcaatct tttttgatat gcaccttagg
   101881 tactggggac gtcgctaact aactctgtga gtctgtatgg aaatccaatg ctaaatttat
   101941 caagatttcc aacaatctca tcaaagtgga tttagctgac tgatttttga acctaaggtt
   102001 tcaaaaatcc ccacataaca gtacagcggt gcatatccct ctagcaagtc ttcgacttgc
   102061 ctctaacgat tttagagtac agtattactc actattctgc gtcttctgct aaaagtttaa
   102121 ctcgtgtttc ttcatccaaa agtgggtaac ctaggcgttt gcgttctgca acaaaggttt
   102181 tggctacaac acgggccaag ttacggatac gagcgatata gcctgcacgc tctgttacag
   102241 atacggcacc acgcgcgtca agcagattaa aggtatgtga acatttgaga acatagtcat
   102301 aggcagggtg taccaagcct tcttctaatg cacgaccagc ttctttttca aacttatcaa
   102361 aattttcaag caacatttct tggtccgaaa tttcaaatga atattttgag tgctcatact
   102421 caggctggat aaagatttct ccgtatttta caccatcagc ccactcgata tcatagacag
   102481 agtctacttc ttgaatgtaa gaagccaagc gctccaaacc ataggtaact tccgcagtca
   102541 cagggctagt tgccaatcca ccgacttgtt ggaaataagt gaactgagtg atttccattc
   102601 cgtcaagcca aacttcccaa ccaagaccag ctgaaccagt tgatgggttt tcccagttgt
   102661 cctcaacaaa acgaatatcg tgctccaaag gattgattcc caatttttcc aaagactcaa
   102721 ggtaaagttc ttggatattt gatggagaag gcttcatgac cacctggaat tggtggtgtt
   102781 ggtagagacg gttagggttt tccccataac gaccgtcagc aggacgacgt gatggctcta
   102841 cataagctgc attccatggc tcaggtccga tagcacgaag gaaagtgtaa ggactcattg
   102901 ttcccgcacc tttttcatta tcataagcct gcataagcat acaaccttgg tcattccaaa
   102961 attgttgcaa agtaaggatg atttcctgga aagtcaattt cttagacatt gtttactcct
   103021 ttagttttta tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa
   103081 aagttttttc tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta
   103141 aattttctac caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg
   103201 catagttctt atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ccatacttct
   103261 tctgaaaaag ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg
   103321 tcaagaaata cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt
   103381 cataaccatc aaaatcatct aaaaaatgct ccgaccaatg agctaactca tgtcctacaa
   103441 tctgtaagag gaaattttca gataaagaat gatagtgact ttctattgct tgagtttgct
   103501 cagaacactc gtagtccatc aattgataca aatacaactc tttccaaaca gctaaatcag
   103561 gcgccataac cattcgtcta ttatttgtat aggctggaac agcgctttcc ctaataatct
   103621 gtgtagcagc attaaaatct gaccaaataa cggcttgcgg taaatcacag actgcaagtt
   103681 cattctttaa aaaagattga taatctttca acttttcagt atttcttact acaaaatcac
   103741 gaaatgtagc tagttgacta tcgtctttta caagataaag gttgtccacg gctctccttt
   103801 ctttcacaca atagactgaa taagcaaaag aaccacatct gacaatccta ggttgattta
   103861 acctaggggc gtcagaaacg cggttccacc ctaatttatt acttcattgt ttttgaaaat
   103921 actacagaaa gcgccagctc attattttgc cctacttggc tcccactgtc ccaagctcgc
   103981 ttgaagaacg ccataagact ttctttcctg ctgactatta tatcaaaaat tagaataatg
   104041 tacaattctt tttatgattt tctagaaatc cacatcatca actcgtggag cccccgactg
   104101 aacagcagtc gtttttaagg tttctctctc ctcatgactc agttcaattc caaaacaatc
   104161 aagattagct tgaatacgag aggttgtgac agattttgga agtggtaaaa atccttctgc
   104221 caagctccag gccaaggcta tctgagcaac cgattttccg tgatttgctg cgatttcttg
   104281 gacttgcttg ctatcaaaca gttctccttg tccaaaaggc ccccaagctt ccaataaaat
   104341 tcccttttca cgacagtaag ctacgacttc ctcttgatac acacctggcg ccaagcgaac
   104401 ttgattgacc gcaggaacga tagttgcagt ttcaagcaag gcatccaaat gatggggaag
   104461 aaaattgcta acgccgatag cacggatttt cccttcttga tagaggtctt ccatcgctct
   104521 ccaaacttcc gcattgcgag ttttccatgc gtcattttct ctgagcggtt ttgggttcgg
   104581 ccaatgaatc aaatacaaat ccaaataatc caagcccagt ttttctatag atttttccaa
   104641 agcttgacga gtttgctcat aggtttgctg actattccaa agcttggtag ttacgaacat
   104701 ttcttcacgt ggaactccgc tatctttgat tgcttgacca acactttctt cattctgata
   104761 aatcgccgcc gtatcaatat gacgataacc agccttcaag gattctaaca ctgcacgata
   104821 ggcttcttct ccatccttag ccttaaaagt tccaaatccc aatactggaa tttctactcc
   104881 attatttaat tgataggtat tcatatgctt ctccttctat atttattcat caattatagc
   104941 ataaaacatt ttttaagtag tactatcttc tgtaaaaaat aagtctgtca aatatctaac
   105001 agacctattt tttcttgctt attcatcacg actatagtac agctcatgag cttttaggcg
   105061 agtattgagc atctctggta tggtcacaaa ggtataacct tgatttttca aatactcaat
   105121 gacccttggc aaggcattga ctgtcggact gtgaatatca tgcatcaaaa cgatagagcc
   105181 gttagctact tgatgctgaa tttctgtcaa aatagatgct tcatttttac tcttccagtc
   105241 cagactatcc acatcccaca tgataaagct caaatccaag ctattgcgaa tatcatctgt
   105301 aatagcacca taaggtggac gcatgagttt agaactagaa cccagcactt tagttagcac
   105361 atcctcagta tcagtaatct gctttttagc ttcatcaaga gagagttgcg agagaatcgg
   105421 atggctccaa ctatggtttc caacaacatg accttcagat tttatcctct tcaccaagtc
   105481 ctcattccca gaaacatttt tcccaagcac aaagaaagtc gctttaatat catatttagc
   105541 tagggtctct aatacctgcg gggtcgttgc tggatttgga ccatcatcaa aggttagagc
   105601 gacaactttt tgatatttct tatcaaagta agattggtac aaggccgcat ctttttcgag
   105661 taagtacgaa gattggataa catcaaagaa agcagatact ggcaaggcta tctcttctaa
   105721 attttcaacc acaggacttg gataaaggat aatctgacta tccttgtaat caaaattcca
   105781 tgcagacaag tcttggtcag agaagttttt tacaatctgc tcactctggt cttgctctat
   105841 ttttttatcc tctatgaagg aggtcaactc ttttatcagc tgttccttag ccttactagc
   105901 atctgaaaac agttggtcaa gtgtaaaagg ttgcccatct tctgttaagt gaacctttcc
   105961 tagactggtc ttttcagtct cttcaacctt aaaagcaact aaatcataga tttgtttggt
   106021 cacattacga ttaacgactc cctttaaacc tgactcttct tgctctgtat agtagaaaac
   106081 aagattgtcc ttactttcta gcttgtcctt aacatcttga tttatcaact ccctaacaga
   106141 ggaaatcact ttctcccctt ggagaggata ataggcaatc acttcggctt gcccctgacg
   106201 aaaatgctcc ttctgatttc cctcactcaa ttgatcatct ttctcttttt tgagcgattc
   106261 aatcttttgc tcaaaacttt tttgctggta gatcttaaaa gcaataaatc cgcctaatag
   106321 gcaaatagaa attgctaaaa taccaatcaa agccaataat acatgtctcg ttttcccgtg
   106381 tctgccacgt cctagtctac ttttattcat atttatatca taacaaattt gagcaataat
   106441 ttcaatgata caatttggca atccacaatt cctctagcaa gccaaagcat cttacatcaa
   106501 ctccaacatc cgtatctgta gagattatgt agttttctat ctatggaatt tctagtagat
   106561 tgaagctaga atagtagacc tatacttcta aaacattgtt agaaatcgat ttgattgtcc
   106621 tgatcgattt gtcctgttct catttcattt tactataaaa ctatgaaaag ctaggtcatc
   106681 tgagaagtaa ttactatcga caattgcgat agcgtatact ggtgcgattt gtttgtagct
   106741 ctggtgggta tcaccttcac gttggcgaat tttttctagg ttttgattaa cctgactgca
   106801 cagataagcc cataggcgat tgatgaaaaa attctgatga tgaacctgaa tttcgatgat
   106861 aacttggatt ccattatcta actccgccaa gacgtctata ctagtataga aatcctgcgc
   106921 tgagtagggc atggaaggca agacgtgaat gttacttccc tccaaaatcg tcacattttt
   106981 tgctggcaag tccagcatat cgcggataaa ttgacaaatc attagttggg ctgatacccg
   107041 gatgtctgag aatcctcctt ttcctccttc tattatagca catttttaaa tctaggtttg
   107101 ctagattcta tgcttctatc tatttattcg gaaaagaaag ctaatagctt atttgaaatt
   107161 ttctcctctc tgttggatag tcccgtctat ctatgttata atgaaagaag gatttaaaat
   107221 cggaaaagga gtatttatgc taaaattagg tgtcatcgga actggcgcta tcagccatca
   107281 tttcatagaa gcagcccata ccagtggaga ataccaactg gtcgcaatct attctagaaa
   107341 actagaaact gcagcaacct ttgcttctcg ctatcagaat atccaactat tcgatcaatt
   107401 agaagtcttc ttcaaatctt cttttgattt agtctatatc gccagtccaa actccttaca
   107461 ttttgctcag gcaaaagctg ccttgtctgc tggtaaacat gttattctcg aaaagccagc
   107521 tgtcactcaa ccacaagaat ggtttgattt gattcaaaca gctgaaaaaa ataactgttt
   107581 tatctttgaa gcagctcgta attaccacga gaaagccttt actactatca aaaacttttt
   107641 agcagataag caagtgttag gagcagattt caactatgcc aaatactctt ccaagatgcc
   107701 tgacttgttg actggacaaa caccaaatgt cttttcaaac cgttttgctg gtggagccct
   107761 catggatttg gggatttatc ccctctatgc tgctgttcgt ctttttggaa aagccaatga
   107821 cgcgacttac catgctcaac agcttgacaa tagcattgac ctaaatggag atggtatcct
   107881 cttctaccca gactatcaag ttcacatcaa ggctggaaaa aacatcactt ccaatcttcc
   107941 ttgcgagatt tatacaacag atggaacctt gactctcaac acgattgagc atattcgctc
   108001 agctattttt accgaccacc aaggaaatca agtccagctt cctatccaac aggctcctca
   108061 tacgatgact gaggaagtcg ctgcatttgc acacatgatc cagcaaccag atctgaatct
   108121 ctaccaaact tggctgtatg atgcaggctc tgttcatgag ctactatata ccatgcgcca
   108181 gactgctggc attagatttg aggcagaaaa atgaaaacca aactaccgac tgaatggcaa
   108241 gaactgagtg accaactcgg tttccaagaa ttcaccccca ttcaaactca actatttgag
   108301 ccccttcttg ctggagaaaa cctcctagga gtgagccaaa ccggaactgg taagacccta
   108361 gcgtatctcc taccaagtct tctcagacta caaaagaaaa aagcccaaca actcttgatt
   108421 ctagcaccaa acacggaact tgctggacag atttttgatg tatgtaaaac gtgggcagaa
   108481 gctatcggat tgactgctca actcttcctt tcaggttcaa gtcagaaacg acaaattgaa
   108541 cgccttaaaa aggggccaga aattctgatt ggaactcctg gccgtatctt tgaactcatt
   108601 aaacttaaaa aaatcaagat gatgaatgtg gaaaccatca tcctggatga atttgaccaa
   108661 ttactagatg attctcagat tcactttgta gaaaaaatca ctcactacgc acctcgtgac
   108721 caccaactgg tctacatgag tgccacgacc aagtttgacc aagaaaagat tgtgccgaat
   108781 acacgcacta ttaatctctc tgaccaaaaa ttggacaata tccagcattt ctacatgcag
   108841 gtagaccaac gtcatcgagt ggatatgcta cgaaaactgg ctcatgtaga ggatttccgt
   108901 ggtctagtct tcttcaatag cctgtcagac cttgggaatg ccgaggaaaa actacagtat
   108961 cgtgatatat tgactgtttc cctcgctagt gatgttaatg ttaaatttag aaaaatcatc
   109021 ttagaaaagt ttaaagataa ccaactaacc ctgcttcttg caactgacct tttggctcgt
   109081 ggaattgata tcgatagcct agaatgtgtc gtaaactttg atattcctag agatagcgaa
   109141 acctacacac accgtgctgg ccgtactggc cgtatgggca aggaaggata tgttattact
   109201 ctcgtcactc atccagaaga aatcaaaaaa cttaaaaagt ttgcaagtat ccgagaaatt
   109261 gtcctaaaaa accaagaact ctatatcaaa taaagcccca ttgctctata cacatccagt
   109321 gtatggagct tttttataag caattcaatt ttatactcat ctgctttcaa aaagcattct
   109381 attccatctc cgattaacga tggactttat cacctccttc tccagtcctt gtatgacatc
   109441 ttggagttga ttcatgacat cttccaaagt tcgaaaggct ttattcttaa atccacgttt
   109501 acgaatctct ttccacactt gttcaatggg ttcatctctg gtgtgtatgg aggaataaag
   109561 gtaaaatcaa tattagtcgg aatctttaag gtacttgatt tatgccatat agcattgtcc
   109621 ataacgagta aaaaataatc atctggataa gcttgtgaaa gctcttctaa aaagacgttc
   109681 atccactcag tattacatcc accagctatt aagaaaaatg attcgcctgt atggggcatc
   109741 aacagctcca taacaatagc gaaattctcg tatatagtga ctatggacat gtggacctac
   109801 tcctattgga gaccaacaag atcccagttt actgattcta ccgaaaccag cctcatcttg
   109861 gtacatcaag cgaaccttat gaaaaggtct actggtttta aagcgctttc ttgtcttctt
   109921 gaattgagat tttattttta gacgcgacaa tggtttgagc gtctgctttc ctaggatgtt
   109981 ctggacgtgg cataatattt cgccaaccat ggtgcttcaa cagttgatag aaggcatcac
   110041 gtgtgtagga acgatataag cctgaaataa ggtattgtaa caaattctcc tgcctctgta
   110101 gccttcaaat ggcgggcaag aaaggctttc tcttcctcaa ctgtcatata tgcatggtta
   110161 cgaccaccac gtgtttcttg aaggagagag tcgagtccga actcctcata tttttttaca
   110221 tttcgccaaa tcgttgtttg attacagtct aaaagatcta taatctcttt ataagatttg
   110281 cccatcagac gaaatagaac gatttgaagg cgtttatgat atttagctgt acgaaagtct
   110341 tttaaaagtg ttttgatggt ttggatttct tctttagttg atttcatatt actattgtat
   110401 aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa accgcgtcag
   110461 cttcgccttg tcgtatagaa tgttactgac ttcgtcagtt ctatctacaa cctaaaaaca
   110521 gtgttttgag cagtctgcag ctaactttct ataacaaaat gaaataagaa caagacaaat
   110581 caatcaagac aatcaaatcg atttctaaca atgttttaga agtagatgtg tactattcca
   110641 gtttcaatat attatagttt gctctttgat tttcattgag tattagttca atatctaaaa
   110701 aaagaggctc tataatattt gtagtgggta aatcccctat agatattatg gagcctattt
   110761 ttgtgtagaa aaaaagtccc atatgaccta taatgaaaag cgacaaaaca actcattaga
   110821 aagaatcata tggaacaatt acattttatc acaaaattac tagacattaa agaccctaat
   110881 atccagattt tagacatcat caataagaat acacacaagg aaatcatcgc caaactggac
   110941 tacgacgcac catcttgccc tgagtgcgga aaccaattga agaaatatga ctttcaaaaa
   111001 ccgtctaaga tcccttacct cgaaacaact ggtatgccta ctagaattct ccttagaaag
   111061 cgtcgattca agtgctatca ctgttcaaaa atgatggtcg ctgaaacttc tatcgtcaag
   111121 aagaatcacc aaatccctcg tatcatcaac caaaagattg ctcaaaagtt aattgaaaag
   111181 atttctatga ctgatattgc ccatcagctt tccatctcaa cttcaactgt cattcgcaag
   111241 ctcaatgatt ctcactttga gcatgatttt tcgcgtcttc ctgagattat gtcctgggac
   111301 gttgaaacag tccggggagt gactgtttca atcgggagat ggagatgagc ttcattgcgc
   111361 aagattttaa caatctcaat atcatcactg ttcttgaggg tagaacacaa gctgtcatcc
   111421 gagatcactt tcttaaatat gatagagccg tccgatgtcg cgtcaaaatt attactatgg
   111481 atatgtttag tccttactat gacttagcta aacagcttcg ctttcaaatt tctaggctca
   111541 ggctgaaaca gtctcccaga ctgtttcact cccgaatgct aaaatcgttc ttgatcgctt
   111601 tcacattgta caacatctta gccgtactat gagtcgtgtg cgtgtccaaa tcatgaatca
   111661 gtttcatcga aagtctcatg aatacaaggc tatcaagcgc tactggaagc tcatacaaca
   111721 ggatagtcgt aaactgagtg ataagcgatt ttatcgtcct acttttcgta tgcacttaac
   111781 caataaagag attttaaaca agcttttgag ttattcggaa gacttgaaac accactatca
   111841 gctctatcaa ctcttgctgt ttcactttca gaataaggaa ccggagaaat ttttcggact
   111901 cattgaggac aatcttaagc aggttcatcc tctttttcag actgtcttta aaacctttct
   111961 aaaggacaaa gagaaaatcg tcaacgccct tcaactaccc tattcaaacg ccaaattgga
   112021 agcgaccaat aatctcatca aacttatcaa gcgcaatgcc tttggttttc ggaactttga
   112081 aaacttcaaa aaacggattt tcatcgccct gaacatcaaa aagaaaggac gaaatttgtc
   112141 ctttctcgag cttagttttt tttcaaccca ctacagttga caaagaacca aaaaagaacc
   112201 ttgccaagca agattctttt agtgtctgac ttaaataatt gttcttctgg gaactaaatc
   112261 gaattaagct tcgatttctg taaccatacc tgaaccaaca gtacgtccac cctcacggat
   112321 agagaatgta gtaccttgtt ctacggcgat tggatgaatc aactcaacgt cgattgtcac
   112381 gttatcacca ggcattacca tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc
   112441 agtagtacgg aagtagaatt gtggacggta gttgttgaag aatggagtgt gacgtccacc
   112501 ttcttcttta gtaaggatgt agacttcacc tttgaattta gtgtgtgggt tgattgaacc
   112561 tggtttagcg ataacttgtc cacgttcgat ttcatcacgt tgaacaccac gaagaaggac
   112621 acctacgtta tctccagcaa gaccttcgtc aagttgttta cggaacattt caacaccagt
   112681 aacaactgct ttttgagttt cttctttgat accaacgatt tcgatttcgt cgttgacttt
   112741 aacgatacca cggtcgatac gtcctgaagc aactgtacca cgtccagtga ttgagaatac
   112801 gtcctcgact ggaagaagca atggtttgtc agtgtcacgt tctggttctg ggatatactc
   112861 atcaactgtg ttcatcaatt ccataacgat gtcttcgtat ttagagtcac cttcaagagc
   112921 tttaagtgct gaaccttgga taactggaag atcgtcacct gggaagtcgt attctgacaa
   112981 taggtcacgg atttccattt caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac
   113041 tttgttcatg aagacgataa ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc
   113101 acgagtttgt ggcattggtc cgtcagttga agctactaca aggatagctc cgtccatttg
   113161 agcagcacca gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc
   113221 gtagtgacgt ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc
   113281 gcgttcttct ggagcagcat cgatagacgc atagtcttta ggttggttaa ctgatgaagg
   113341 caagcgacgt gccaaaacag ttgtgatagc tgcagttagg gtagttttac cgtggtcaac
   113401 gtgtccgata gtaccaatgt taacatgtgg tttactacga tcgtattttt cttttgccat
   113461 ttgagtaaaa gcctccaata aaatatattt tatagataga cagtaggcaa tacagtctaa
   113521 ctttccttac tattttatca aatttcagct aaattgcaag tgttttacaa cgtttttgtg
   113581 aattattctt ggtaaaaatt taa
//
LOCUS       DBERCW010000003       104582 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.003, whole genome shotgun sequence.
ACCESSION   DBERCW010000003 DBERCW010000000
VERSION     DBERCW010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 104582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 104582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..104582
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.003"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..245
                     /locus_tag="ACL72M_000253"
     CDS             <1..245
                     /locus_tag="ACL72M_000253"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715448.1"
                     /translation="YNSPCCGWILFSLLILFETLFKPRQLHLAVYVLLTSSVLSTTSK
                     QCFELTSSVLSATSKQCFEQPAASFLVCSLIFIEYY"
     gene            303..959
                     /locus_tag="ACL72M_000254"
     CDS             303..959
                     /locus_tag="ACL72M_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGS0715449.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            949..1272
                     /locus_tag="ACL72M_000255"
                     /pseudo
     CDS             949..1272
                     /locus_tag="ACL72M_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
     gene            1376..2206
                     /locus_tag="ACL72M_000256"
     CDS             1376..2206
                     /locus_tag="ACL72M_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0715450.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2360..3214
                     /locus_tag="ACL72M_000257"
     CDS             2360..3214
                     /locus_tag="ACL72M_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS0715451.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3314..4687
                     /locus_tag="ACL72M_000258"
     CDS             3314..4687
                     /locus_tag="ACL72M_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGS0715452.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYHTHIELVE
                     ELIRSYE"
     gene            4680..5741
                     /locus_tag="ACL72M_000259"
     CDS             4680..5741
                     /locus_tag="ACL72M_000259"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGS0715453.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5743..6435
                     /locus_tag="ACL72M_000260"
     CDS             5743..6435
                     /locus_tag="ACL72M_000260"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGS0715454.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6464..7033)
                     /locus_tag="ACL72M_000261"
     CDS             complement(6464..7033)
                     /locus_tag="ACL72M_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS0715455.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7168..7782
                     /locus_tag="ACL72M_000262"
     CDS             7168..7782
                     /locus_tag="ACL72M_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS0715456.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7760..9430
                     /locus_tag="ACL72M_000263"
     CDS             7760..9430
                     /locus_tag="ACL72M_000263"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0715457.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9442..10728
                     /locus_tag="ACL72M_000264"
     CDS             9442..10728
                     /locus_tag="ACL72M_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0715458.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10780..11313
                     /locus_tag="ACL72M_000265"
     CDS             10780..11313
                     /locus_tag="ACL72M_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715459.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11391..11861
                     /gene="nrdI"
                     /locus_tag="ACL72M_000266"
     CDS             11391..11861
                     /gene="nrdI"
                     /locus_tag="ACL72M_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGS0715460.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12154..13416)
                     /locus_tag="ACL72M_000267"
     CDS             complement(12154..13416)
                     /locus_tag="ACL72M_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGS0715461.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMATLPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13726..14184)
                     /locus_tag="ACL72M_000268"
     CDS             complement(13726..14184)
                     /locus_tag="ACL72M_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGS0715462.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14181..14621)
                     /locus_tag="ACL72M_000269"
     CDS             complement(14181..14621)
                     /locus_tag="ACL72M_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0715463.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14977..16926
                     /gene="mutL"
                     /locus_tag="ACL72M_000270"
     CDS             14977..16926
                     /gene="mutL"
                     /locus_tag="ACL72M_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGS0715464.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17251..17718)
                     /gene="ribE"
                     /locus_tag="ACL72M_000271"
     CDS             complement(17251..17718)
                     /gene="ribE"
                     /locus_tag="ACL72M_000271"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGS0715465.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17719..18924)
                     /locus_tag="ACL72M_000272"
     CDS             complement(17719..18924)
                     /locus_tag="ACL72M_000272"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGS0715466.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLIERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18944..19579)
                     /gene="ribE"
                     /locus_tag="ACL72M_000273"
     CDS             complement(18944..19579)
                     /gene="ribE"
                     /locus_tag="ACL72M_000273"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGS0715467.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19564..20664)
                     /gene="ribD"
                     /locus_tag="ACL72M_000274"
     CDS             complement(19564..20664)
                     /gene="ribD"
                     /locus_tag="ACL72M_000274"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGS0715468.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20799..20913)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21070..21663
                     /gene="ruvA"
                     /locus_tag="ACL72M_000275"
     CDS             21070..21663
                     /gene="ruvA"
                     /locus_tag="ACL72M_000275"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGS0715469.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTARQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21673..22236
                     /locus_tag="ACL72M_000276"
     CDS             21673..22236
                     /locus_tag="ACL72M_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGS0715470.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     VLLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22233..22910
                     /locus_tag="ACL72M_000277"
     CDS             22233..22910
                     /locus_tag="ACL72M_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0715471.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(23047..24078)
                     /locus_tag="ACL72M_000278"
     CDS             complement(23047..24078)
                     /locus_tag="ACL72M_000278"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGS0715472.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24333..25016)
                     /locus_tag="ACL72M_000279"
     CDS             complement(24333..25016)
                     /locus_tag="ACL72M_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGS0715473.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILTSMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(25028..25972)
                     /locus_tag="ACL72M_000280"
     CDS             complement(25028..25972)
                     /locus_tag="ACL72M_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS0715474.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26104..28935
                     /gene="uvrA"
                     /locus_tag="ACL72M_000281"
     CDS             26104..28935
                     /gene="uvrA"
                     /locus_tag="ACL72M_000281"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGS0715475.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28928..29989
                     /locus_tag="ACL72M_000282"
     CDS             28928..29989
                     /locus_tag="ACL72M_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS0715476.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30121..30519
                     /gene="spx"
                     /locus_tag="ACL72M_000283"
     CDS             30121..30519
                     /gene="spx"
                     /locus_tag="ACL72M_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGS0715477.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30585..31154
                     /locus_tag="ACL72M_000284"
     CDS             30585..31154
                     /locus_tag="ACL72M_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGS0715478.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31241..31507
                     /locus_tag="ACL72M_000285"
     CDS             31241..31507
                     /locus_tag="ACL72M_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGS0715479.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31511..31930
                     /gene="ruvX"
                     /locus_tag="ACL72M_000286"
     CDS             31511..31930
                     /gene="ruvX"
                     /locus_tag="ACL72M_000286"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGS0715480.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31946..32251
                     /locus_tag="ACL72M_000287"
     CDS             31946..32251
                     /locus_tag="ACL72M_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGS0715481.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32509..33759
                     /locus_tag="ACL72M_000288"
     CDS             32509..33759
                     /locus_tag="ACL72M_000288"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS0715482.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33843..34298
                     /locus_tag="ACL72M_000289"
     CDS             33843..34298
                     /locus_tag="ACL72M_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGS0715483.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQVQQPAQQN
                     TNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDG
                     DQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34444..35976
                     /gene="cls"
                     /locus_tag="ACL72M_000290"
     CDS             34444..35976
                     /gene="cls"
                     /locus_tag="ACL72M_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGS0715484.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36234..37772
                     /locus_tag="ACL72M_000291"
     CDS             36234..37772
                     /locus_tag="ACL72M_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGS0715485.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWGLHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37892..40099
                     /gene="nrdD"
                     /locus_tag="ACL72M_000292"
     CDS             37892..40099
                     /gene="nrdD"
                     /locus_tag="ACL72M_000292"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGS0715486.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40111..40251
                     /locus_tag="ACL72M_000293"
     CDS             40111..40251
                     /locus_tag="ACL72M_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715487.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40295..40801
                     /locus_tag="ACL72M_000294"
     CDS             40295..40801
                     /locus_tag="ACL72M_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0715488.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            40794..41384
                     /gene="nrdG"
                     /locus_tag="ACL72M_000295"
     CDS             40794..41384
                     /gene="nrdG"
                     /locus_tag="ACL72M_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGS0715489.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41392..42009
                     /locus_tag="ACL72M_000296"
     CDS             41392..42009
                     /locus_tag="ACL72M_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS0715490.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42275..42583
                     /gene="rpsJ"
                     /locus_tag="ACL72M_000297"
     CDS             42275..42583
                     /gene="rpsJ"
                     /locus_tag="ACL72M_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGS0715491.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42800..43426
                     /gene="rplC"
                     /locus_tag="ACL72M_000298"
     CDS             42800..43426
                     /gene="rplC"
                     /locus_tag="ACL72M_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGS0715492.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43451..44074
                     /gene="rplD"
                     /locus_tag="ACL72M_000299"
     CDS             43451..44074
                     /gene="rplD"
                     /locus_tag="ACL72M_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGS0715493.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44074..44370
                     /locus_tag="ACL72M_000300"
     CDS             44074..44370
                     /locus_tag="ACL72M_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGS0715494.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44388..45221
                     /gene="rplB"
                     /locus_tag="ACL72M_000301"
     CDS             44388..45221
                     /gene="rplB"
                     /locus_tag="ACL72M_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGS0715495.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45325..45606
                     /gene="rpsS"
                     /locus_tag="ACL72M_000302"
     CDS             45325..45606
                     /gene="rpsS"
                     /locus_tag="ACL72M_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGS0715496.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45618..45962
                     /gene="rplV"
                     /locus_tag="ACL72M_000303"
     CDS             45618..45962
                     /gene="rplV"
                     /locus_tag="ACL72M_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGS0715497.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45975..46628
                     /gene="rpsC"
                     /locus_tag="ACL72M_000304"
     CDS             45975..46628
                     /gene="rpsC"
                     /locus_tag="ACL72M_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGS0715498.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46632..47045
                     /gene="rplP"
                     /locus_tag="ACL72M_000305"
     CDS             46632..47045
                     /gene="rplP"
                     /locus_tag="ACL72M_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGS0715499.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            47055..47261
                     /gene="rpmC"
                     /locus_tag="ACL72M_000306"
     CDS             47055..47261
                     /gene="rpmC"
                     /locus_tag="ACL72M_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGS0715500.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47286..47546
                     /gene="rpsQ"
                     /locus_tag="ACL72M_000307"
     CDS             47286..47546
                     /gene="rpsQ"
                     /locus_tag="ACL72M_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGS0715501.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47572..47940
                     /gene="rplN"
                     /locus_tag="ACL72M_000308"
     CDS             47572..47940
                     /gene="rplN"
                     /locus_tag="ACL72M_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGS0715502.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            48018..48323
                     /gene="rplX"
                     /locus_tag="ACL72M_000309"
     CDS             48018..48323
                     /gene="rplX"
                     /locus_tag="ACL72M_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGS0715503.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48347..48889
                     /gene="rplE"
                     /locus_tag="ACL72M_000310"
     CDS             48347..48889
                     /gene="rplE"
                     /locus_tag="ACL72M_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGS0715504.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48907..49176
                     /gene="rpsN"
                     /locus_tag="ACL72M_000311"
     CDS             48907..49176
                     /gene="rpsN"
                     /locus_tag="ACL72M_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGS0715505.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49461..49859
                     /gene="rpsH"
                     /locus_tag="ACL72M_000312"
     CDS             49461..49859
                     /gene="rpsH"
                     /locus_tag="ACL72M_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGS0715506.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            50051..50587
                     /gene="rplF"
                     /locus_tag="ACL72M_000313"
     CDS             50051..50587
                     /gene="rplF"
                     /locus_tag="ACL72M_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGS0715507.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50671..51027
                     /gene="rplR"
                     /locus_tag="ACL72M_000314"
     CDS             50671..51027
                     /gene="rplR"
                     /locus_tag="ACL72M_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGS0715508.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            51045..51539
                     /gene="rpsE"
                     /locus_tag="ACL72M_000315"
     CDS             51045..51539
                     /gene="rpsE"
                     /locus_tag="ACL72M_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGS0715509.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51553..51735
                     /gene="rpmD"
                     /locus_tag="ACL72M_000316"
     CDS             51553..51735
                     /gene="rpmD"
                     /locus_tag="ACL72M_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGS0715510.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51880..52320
                     /gene="rplO"
                     /locus_tag="ACL72M_000317"
     CDS             51880..52320
                     /gene="rplO"
                     /locus_tag="ACL72M_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGS0715511.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52333..53643
                     /gene="secY"
                     /locus_tag="ACL72M_000318"
     CDS             52333..53643
                     /gene="secY"
                     /locus_tag="ACL72M_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGS0715512.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53794..54432
                     /locus_tag="ACL72M_000319"
     CDS             53794..54432
                     /locus_tag="ACL72M_000319"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGS0715513.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54549..54767
                     /gene="infA"
                     /locus_tag="ACL72M_000320"
     CDS             54549..54767
                     /gene="infA"
                     /locus_tag="ACL72M_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGS0715514.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54792..54908
                     /gene="rpmJ"
                     /locus_tag="ACL72M_000321"
     CDS             54792..54908
                     /gene="rpmJ"
                     /locus_tag="ACL72M_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGS0715515.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54926..55291
                     /gene="rpsM"
                     /locus_tag="ACL72M_000322"
     CDS             54926..55291
                     /gene="rpsM"
                     /locus_tag="ACL72M_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGS0715516.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55309..55692
                     /gene="rpsK"
                     /locus_tag="ACL72M_000323"
     CDS             55309..55692
                     /gene="rpsK"
                     /locus_tag="ACL72M_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGS0715517.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55735..56670
                     /locus_tag="ACL72M_000324"
     CDS             55735..56670
                     /locus_tag="ACL72M_000324"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGS0715518.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56682..57068
                     /gene="rplQ"
                     /locus_tag="ACL72M_000325"
     CDS             56682..57068
                     /gene="rplQ"
                     /locus_tag="ACL72M_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGS0715519.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57333..57599
                     /locus_tag="ACL72M_000326"
     CDS             57333..57599
                     /locus_tag="ACL72M_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGS0715520.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57609..58946
                     /locus_tag="ACL72M_000327"
     CDS             57609..58946
                     /locus_tag="ACL72M_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGS0715521.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59190..59882
                     /locus_tag="ACL72M_000328"
     CDS             59190..59882
                     /locus_tag="ACL72M_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0715522.1"
                     /translation="MVKVRLYLIRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59985..61621)
                     /locus_tag="ACL72M_000329"
                     /pseudo
     CDS             complement(59985..61621)
                     /locus_tag="ACL72M_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61611..62701)
                     /locus_tag="ACL72M_000330"
                     /pseudo
     CDS             complement(61611..62701)
                     /locus_tag="ACL72M_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62714..63820)
                     /locus_tag="ACL72M_000331"
                     /pseudo
     CDS             complement(62714..63820)
                     /locus_tag="ACL72M_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(64052..64276)
                     /locus_tag="ACL72M_000332"
                     /pseudo
     CDS             complement(64052..64276)
                     /locus_tag="ACL72M_000332"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(64324..65100)
                     /locus_tag="ACL72M_000333"
     CDS             complement(64324..65100)
                     /locus_tag="ACL72M_000333"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGS0715523.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            65222..65968
                     /locus_tag="ACL72M_000334"
     CDS             65222..65968
                     /locus_tag="ACL72M_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0715524.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65981..66961
                     /locus_tag="ACL72M_000335"
     CDS             65981..66961
                     /locus_tag="ACL72M_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGS0715525.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67156..67476
                     /locus_tag="ACL72M_000336"
     CDS             67156..67476
                     /locus_tag="ACL72M_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0715526.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67522..67830
                     /locus_tag="ACL72M_000337"
     CDS             67522..67830
                     /locus_tag="ACL72M_000337"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0715527.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67847..69145
                     /locus_tag="ACL72M_000338"
     CDS             67847..69145
                     /locus_tag="ACL72M_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0715528.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            69296..71734
                     /locus_tag="ACL72M_000339"
     CDS             69296..71734
                     /locus_tag="ACL72M_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGS0715529.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71753..72421
                     /locus_tag="ACL72M_000340"
     CDS             71753..72421
                     /locus_tag="ACL72M_000340"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGS0715530.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLVLAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            72439..73527
                     /locus_tag="ACL72M_000341"
     CDS             72439..73527
                     /locus_tag="ACL72M_000341"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGS0715531.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            73982..76483
                     /gene="leuS"
                     /locus_tag="ACL72M_000342"
     CDS             73982..76483
                     /gene="leuS"
                     /locus_tag="ACL72M_000342"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGS0715532.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            76677..77372
                     /locus_tag="ACL72M_000343"
     CDS             76677..77372
                     /locus_tag="ACL72M_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS0715533.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            77384..77800
                     /locus_tag="ACL72M_000344"
     CDS             77384..77800
                     /locus_tag="ACL72M_000344"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0715534.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(78615..78707)
                     /locus_tag="ACL72M_000345"
     CDS             complement(78615..78707)
                     /locus_tag="ACL72M_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGS0715535.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            78841..79839
                     /gene="ruvB"
                     /locus_tag="ACL72M_000346"
     CDS             78841..79839
                     /gene="ruvB"
                     /locus_tag="ACL72M_000346"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGS0715536.1"
                     /translation="MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            79820..80392
                     /locus_tag="ACL72M_000347"
     CDS             79820..80392
                     /locus_tag="ACL72M_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HGS0715537.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            80623..81381
                     /locus_tag="ACL72M_000348"
     CDS             80623..81381
                     /locus_tag="ACL72M_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGS0715538.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            81390..82193
                     /locus_tag="ACL72M_000349"
     CDS             81390..82193
                     /locus_tag="ACL72M_000349"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGS0715539.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            82215..83474
                     /gene="rseP"
                     /locus_tag="ACL72M_000350"
     CDS             82215..83474
                     /gene="rseP"
                     /locus_tag="ACL72M_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGS0715540.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRHKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            83487..85340
                     /locus_tag="ACL72M_000351"
     CDS             83487..85340
                     /locus_tag="ACL72M_000351"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGS0715541.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            85440..86819
                     /gene="bglA"
                     /locus_tag="ACL72M_000352"
     CDS             85440..86819
                     /gene="bglA"
                     /locus_tag="ACL72M_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS0715542.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            87011..88819
                     /gene="glmS"
                     /locus_tag="ACL72M_000353"
     CDS             87011..88819
                     /gene="glmS"
                     /locus_tag="ACL72M_000353"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGS0715543.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            88938..89987
                     /locus_tag="ACL72M_000354"
     CDS             88938..89987
                     /locus_tag="ACL72M_000354"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGS0715544.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(90087..93884)
                     /gene="spuA"
                     /locus_tag="ACL72M_000355"
     CDS             complement(90087..93884)
                     /gene="spuA"
                     /locus_tag="ACL72M_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGS0715545.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDTHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVKIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEASV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            94300..94713
                     /gene="rpsL"
                     /locus_tag="ACL72M_000356"
     CDS             94300..94713
                     /gene="rpsL"
                     /locus_tag="ACL72M_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGS0715546.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            94733..95203
                     /gene="rpsG"
                     /locus_tag="ACL72M_000357"
     CDS             94733..95203
                     /gene="rpsG"
                     /locus_tag="ACL72M_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGS0715547.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            95627..97708
                     /gene="fusA"
                     /locus_tag="ACL72M_000358"
     CDS             95627..97708
                     /gene="fusA"
                     /locus_tag="ACL72M_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGS0715548.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            97812..102203
                     /locus_tag="ACL72M_000359"
     CDS             97812..102203
                     /locus_tag="ACL72M_000359"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGS0715549.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            102305..102568
                     /locus_tag="ACL72M_000360"
     CDS             102305..102568
                     /locus_tag="ACL72M_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGS0715550.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            102561..102839
                     /locus_tag="ACL72M_000361"
     CDS             102561..102839
                     /locus_tag="ACL72M_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGS0715551.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            102860..103012
                     /locus_tag="ACL72M_000362"
     CDS             102860..103012
                     /locus_tag="ACL72M_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715552.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            103034..104275
                     /locus_tag="ACL72M_000363"
     CDS             103034..104275
                     /locus_tag="ACL72M_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGS0715553.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            104285..104515
                     /locus_tag="ACL72M_000364"
     CDS             104285..104515
                     /locus_tag="ACL72M_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS0715554.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT        31113 a        19259 c        23331 g        30879 t
ORIGIN      
        1 tatataatag tccatgctgt ggctggattc ttttcagcct acttatactc ttcgaaactc
       61 tcttcaaacc acgtcagctt caccttgccg tatatgtgtt actgacttcg tcagttctat
      121 ccacaacctc aaaacagtgt tttgagctga cttcatcagt tctatctgca acctcaaaac
      181 agtgttttga gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt
      241 attaagacaa tatgaggaga aagatgaaag aaaaaggatt ttaggagggg gcgcaggcag
      301 ccatgccaac ggctcttggc tatgtcagta tcggcctggc ctgtggaatt atcggtgcgc
      361 cctatgtgac acctgttgag atgggcttga tgagtctctt tgtttatgct gggagtgccc
      421 agtttgccat gttggcactg attgtggttc aagctcctgt ggcagctatt gctatgacgg
      481 tttttctaat caatttgcgt ctctttttgt tgagcttaca cgcatcgact tatttccgtc
      541 ataccagtct ttggcacaat atcggtatgt ctagtatctt gacagatgag acctatggcg
      601 ttttgatggg cgaattagcc catacagata aggtcaatcc gatgtggatg cacgggaaca
      661 atctcaacag ctatgtggct tggtttgtgg gaacagtggt cggaacggct ctaggtgacc
      721 tgttgccaaa tccagaaatc tttggtttag attttgccct ggttgggatg tttatcggga
      781 tttttgcttc gcaattccag atgatgcaaa gacggatttc tgtccgcaat ctgctcatta
      841 tcttagcagt tgttgcagtg tccttctttt tacttttgac agtggtgtct cagtcactag
      901 ctgttctgtt tgcgacgcta cttggttgta gcatggggat ggttttagat ggtcagtaag
      961 tatcttttat tagcagttat tttctctggt cttgtgacct ggattccccg tatgattccc
     1021 ttcatcttgg tcaagtataa gggcctgcct acgattgttg agcgtttttt gaagtttttg
     1081 cctgtttcca ttatctttgc cttgattctt tcaagagtag tgacaggtaa ggttgggaac
     1141 cttcctcaaa tcaaatgact ggacttctta gcagtctttc caacagcttg ggtagctttt
     1201 cgctaccgca atctagtcgg tacggttctc tttggagtag tcttgattgc cgtcttgcgt
     1261 ttggtctttt aaataagtca taaagaaaac ttatcacaga gatagatatc atataatggc
     1321 gtaattactt tttttctgat aagattataa ggtattctat tttggaggaa atgacatgaa
     1381 aaaaatcgtt aaatactcat ctcttgcagc ccttgctctt gttgctgcag gtgtgcttgc
     1441 ggcttgctca ggtggtgcta agaaagaagg acaagcagct agcaagaaag aaatcatcgt
     1501 tgcaaccaat ggatcaccaa ggccatttat ctatgaagaa aatggcgaat tgactggtta
     1561 cgagattgaa gtcgttcgcg ctatctttaa agattctgac aaatatgatg tcaagtttga
     1621 aaagacagaa tggtcaggtg tctttgctgg tcttgacgct gaccgttaca atatggctgt
     1681 caacaatctt agctacacta aagaacgtgc ggagaaatac ctctatgccg caccaattgc
     1741 ccaaaatcct aatgtccttg tcgtgaagaa agatgactct agtatcaagt ctctcgatga
     1801 tatcggtgga aaatcgacgg aagtcgttca agccactaca tcagctaagc agttagaagc
     1861 atacaacgct gaacacacgg acaacccaac tatccttaac tatactaagg cagatttcca
     1921 acaaatcatg gtacgtttga gcgatggaca atttgactat aagatttttg ataaaatcgg
     1981 tgttgaaaca gtgatcaaga accaaggttt ggacaacttg aaagttatcg aacttccaag
     2041 cgaccaacaa ccgtacgttt acccacttct tgctcagggt caagatgagt tgaaatcgtt
     2101 tgtagacaaa cgcatcaaag aactttataa agatggaact cttgaaaaat tgtctaaaca
     2161 attcttcgga gacacttatc taccggcaga agctgatatt aaataatttc ttgaaatcat
     2221 ccattctgag taagatgggt ggtttctcag tttttaggga tatagtttta aactatatat
     2281 ctgactatct aataacaatt tgtgaaatca aacaaattgt gagatactag tacggtatta
     2341 tttttaagga gaaagaatca tgaaaatcaa aaaatggctt ggtctagcag cccttgctac
     2401 agtcgcaggt ttggctcttg cagcttgcgg aaactcagaa aagaaagcag acaatgcaac
     2461 aactatcaaa atcgcaactg ttaaccgtag cggttctgaa gaaaaacgtt gggacaaaat
     2521 ccaagaattg gttaaaaaag acggaattac cttggaattt acagagttca cagactactc
     2581 acaaccaaac aaagcaactg ctgatggcga agtagatttg aacgctttcc aacactataa
     2641 cttcttgaat aactggaaca aagaaaacgg aaaagatctt gtagcgattg cagatactta
     2701 catctctcca atccgccttt actcaggttt gaatggaagt gccaacaagt acactaaagt
     2761 agaagacatc ccagcaaacg gagaaatcgc tgtaccaaat gacgctacaa acgaaagccg
     2821 tgcgctttac ttgcttcaat cagctggctt gattaaattg gatgtttctg gaactgctct
     2881 tgcaacagtt gccaacatca aagaaaatcc aaagaacttg aaaatcactg aattggacgc
     2941 tagccaaaca gctcgttcat tgtcatcagt tgacgctgcc gttgtaaaca ataccttcgt
     3001 tacagaagca aaattggact acaagaaagc acttttcaaa gaacaagctg atgaaaactc
     3061 aaaacaatgg tacaacatca ttgttgcgaa aaaagattgg gaaacatcac ctaaggctga
     3121 tgctatcaag aaagtaatcg cagcttacca cacagatgac gtgaaaaaag ttatcgaaga
     3181 atcatcagat ggtttggatc aaccagtttg gtaataagaa acagggaggt gggagagaaa
     3241 attccacctc ttgcttttgt atagagtata gattgtaaag aagactattc gttcatagaa
     3301 aggtagagag aatatggttt ttcctagcga acaagaacag attgaaaaat ttgaaaagga
     3361 tcatgtagtc caacattatt ttgaggtttt gcgtaccttg atttctaaga aatcagtctt
     3421 tgcccagcag gttggactca aggaagtcgc aaattatctg ggtgagattt tcaagcgtgt
     3481 tggagctgaa gtggagattg atgagagcta tacagcgccc tttgtcatgg cacatttcaa
     3541 gagttcgcgt ccagatgcca agaccttgat tttctataac cactatgaca ctgtgccagc
     3601 ggatggggat caggtctgga cagaggatcc ttttacgctt tcggtccgca atggcttcat
     3661 gtatgggcgt ggggttgatg acgacaaggg tcatatcaca gctcgcttga gtgctttgag
     3721 aaaatatatg cagcaccatg atgatttacc tgtcaatatc agctttatca tggagggagc
     3781 ggaggaatcg gcttcaacag acctagataa gtatttggaa aagcatgcag acaaactccg
     3841 tggggcggat ttgttggtct gggaacaagg gaccaaaaat gccttggagc agctggaaat
     3901 ttctggtggc aataagggga ttgtgacctt tgatgccaag gtaaaaagcg ctgatgtgga
     3961 tatccactcg agttatggtg gtgttgtgga atcagctcct tggtatctcc tccaagcctt
     4021 acagtctctt cgtgctgcgg atggccgtat cttggttgaa ggcttgtacg aagaagtaca
     4081 agagcccaat gaacgagaaa tggccttgct agaaacttat ggtcaacgaa acccagagga
     4141 agttagtcgg atttatggat tggagttgcc tctcttacag gaggagcgga tggcctttct
     4201 aaaacgtttc tttttcgagc cagcgcttaa tatcgaagga atccagtctg gttatcaagg
     4261 tcagggtgtt aagactattt tacctgcaga agccagtgcc aagctagagg ttcgtctggt
     4321 tccgggccta gaaccgcatg atgttctgga aaaaattcgg aaacagctag acaaaaatgg
     4381 ctttgataag gtagaattat actatacctt gggagagatg agctatcgaa gcgatatgag
     4441 cgcaccagcc attctcaatg tgatcgagtt ggccaagaaa ttctatccac agggcgtttc
     4501 agtcttgccg acgacagcgg ggacaggacc tatgcatacg gtctttgatg ccctagaggt
     4561 accaatggtt gcattcggtc taggaaatgc caatagccga gaccacggtg gagatgaaaa
     4621 tgtgcgaatc gctgattatc acacccatat cgaattagta gaggagctga ttagaagcta
     4681 tgagtagaga tattatcaag ttagatcaga tcgatgtgac ttttcaccaa aagaagagaa
     4741 ccattacagc ggttaaggat gtgaccattc acatccaaga aggggatatc tacggaatcg
     4801 ttggatattc tggagcagga aaatcaaccc ttgtacgggt gattaatctc ttgcaaaaac
     4861 catctgcagg gaaaattacc attgacgacg atgtgatttt tgacggcaag gtgaccttga
     4921 cggcagagca gttgcgtcgt aaacgtcaag atatcggaat gattttccag cattttaacc
     4981 tgatgagcca aaagacagca gaggagaatg tagcctttgc ccttaaacac tctgaactca
     5041 gcaaggaaga aaagaaggct aaagtagcta agttgttgga cttggttggt ttggcagatc
     5101 gtgctgaaaa ctacccttca caactatctg gagggcaaaa acagcgtgtg gcaattgcgc
     5161 gtgccttggc caatgatcca aaaatcttga tttcagacga gtcaacttct gcccttgatc
     5221 cgaagacaac caagcagatt ttggccttgt tgcaagattt gaaccaaaaa ttaggcttga
     5281 ctgttgtctt gattacgcat gaaatgcaga ttgtcaaaga cattgccaac cgtgtggcgg
     5341 ttatgcagga tgggcatttg attgaagagg gtagtgtgct tgaaatcttc tcagacccta
     5401 aacaaccttt gactcaagac tttatctcaa cagctacagg tattgacgaa gccatggtca
     5461 aaatcgagaa gcaagaaatc gtggaacact tgtctgaaaa cagtctcttg gtgcaactca
     5521 agtacgctgg atcttcaaca gacgagccac ttttgaatga attgtacaag cattatcaag
     5581 taatggctaa tattctctat gggaatatcg aaatcctcga tggtactcct gttggagaat
     5641 tggtggtggt cttgtcaggt gaaaaagcag cgttggcagg tgcccaagaa gccattcgtc
     5701 aagcaggcgt acagttaaaa gtattgaagg gaggacagta agatggaatc attgattcaa
     5761 acctatttgc caaatgtcta taagatgggt tggtctggtc aggcaggctg gggaacagct
     5821 atctacctaa ccctctatat gacagttctt tccttcatta tcggaggctt cttggggcta
     5881 gtggcaggtc tctttctcgt cttgacagcg ccaggtggtg tcttggagaa taaagtcgta
     5941 ttctggattt tagacaaaat tacctcaatt tttcgtgcga ttccctttat catcctcttg
     6001 gcaatcttgt caccactttc tcacttgatt gttaaaacaa gtatcgggcc aaatgcagcc
     6061 cttgtcccac tttcttttgc agtctttgcc ttctttgccc gtcaggtgca ggttgtcttg
     6121 gctgaattgg atggcggtgt cattgaggcg gctcaagcga gcggagcgac tttctgggac
     6181 atcgtgggtg tttacctatc agaaggtctt ccagatttga tccgtgtgac gactgtgacc
     6241 ttgatttccc ttgttgggga aacagctatg gccggtgcgg ttggagctgg tggtatcggt
     6301 aacgtagcca tcgcttatgg atttaaccgc tacaatcacg atgtgaccat cttggcaacc
     6361 attattatca ttttgattat ctttgcaatc caattcttgg gagatttctt gactaagaaa
     6421 ttgagtcata aataaaaaga gccgcgtggc tctttttaac tgatcagatt ttctgtgcaa
     6481 attttttact caaggcttgt ccaatcaagg cacccactag ggctccgatg acaatacttg
     6541 cgataaatag aaggacagtt ccagggtttg gagcgaccat gatacggtcg atatattctt
     6601 gggattttcc tcttgccaga agagtagcca tataggcttt gggcgcaatc cacataagca
     6661 agattggtcc tgttgtacta aaggcgaaaa taatgaaaga aaggaagttc tttgttttgt
     6721 ccttgtattt tcctaaatga gctacttcat ctgctaggag gccacagata attccaggaa
     6781 ggaaggaacc agcaccgtgt ttagttccca agaaaaagag ggcaatgaca aggccgatag
     6841 tggtaatggc tccaaagcgc ggaacttttg cgactaggat catatagacg ctaccgccga
     6901 caagggcagt aaaggcaggc gcataaaaca tgtttccagt ttggtcaaag agattgccca
     6961 aaaggacacc aatccccatg cagaggaagt aaagaactgc aaaaagcagt gtagttaaga
     7021 tagatttctt catgaattgt ctcctgataa ttttttcaca attctcattg taccacggtt
     7081 tggtgggatt gtaaatggat actagaagtt tttgaaaacg cttgaaatat gatataatgg
     7141 tttcatagtt atttttaggg gaatatcatg ggtagatttt tagactttgt ctttaatcgt
     7201 ttctttttag ggatgattgc gacagccttc ttttggctat taactttagc aggagggatt
     7261 atccttggtc tagcgccggc tagtgccacc ttgatgagct tatatgcaga acatggttat
     7321 agctttcggg aatacagttt gaaggaggct tggtctcttt acaagcaaaa ttttgtctca
     7381 agcaacctga ttttctatag ctttttaggt gtgggtctag ttttgaccta tggtttgtat
     7441 ctcttggtgc aattgcctca tcagaccatt gttcatttga ttgcgaccct tttgaatgtc
     7501 ctagtagttg ccctgatctt tttggcttat acagtatctt taaaattaca agtttatttt
     7561 gccttgtcct atcgaaatag tctcaaatta tccttgattg gcatctttat gagtctagca
     7621 gctgtggcca agattctcct tgggactgtg ctacttgtag caattggtta ctatatgcct
     7681 gccctgctat tttttgtagg aattgggatg tggcatttct ttatcagtga tatgttggaa
     7741 cctgtctatg aaatcatcca tgaaaaattg gcgacaaaat agaatgaagc agttttggct
     7801 acatacgctt ctaagaacct atagttcagt gatgatcatt atcattgcga gttttgcaat
     7861 cttactctct tacgctgact gggattcacg tgaaaaggaa gcccagagag tagcccagcg
     7921 tgtaactgct agaacagtga gtgaaattga atattaccat agagagtcaa cccagatagc
     7981 tcaggcttta gttgaaaacc aagctcgtat tgagggaatc tataaatact ttagtcttag
     8041 catgccagac tatttttact ggcaattaga gcggaaagct tcgccttata tatcagtctc
     8101 tctgtatgaa aatgttgatg acctctatgt tcgaaatgat tttgtaactg gagtggccat
     8161 tgcttttcaa gattacaagg aagtctatgt ttctactaaa gacaaacgta gtggagaaaa
     8221 aatcagggct gaggatttca aaccagcagg aaatagtttt gccattccgg tgtcagatcc
     8281 agtgtcagat caagatttag gagtgattta catctccttg gatcctgctg ttttatacca
     8341 tgccattgat aatactagag gtcatactcc gatggcagta acagtgacct caccttttga
     8401 tacggagatt tttcatattg gtgagacagt tgataaggag agtgaaaatt ggctagttgg
     8461 cttaacttct catggatatc aggttcaggt ggcagttcct aaaaactttg ttttacaagg
     8521 aacagtgact agctctgctt tgattgtggg tttgagcctt ctctttattg tcattcttta
     8581 tctgactttg aggcagactt ttgctaatta ccaaaagcag gtagtggatt tagtagaatc
     8641 cattcaagtc attgctcaag gcgaagaggg gcgtcggatt gacatttccg agaaagatca
     8701 ggaattactc ctaatcgcgg agacgaccaa tgatatgttg gatcgattgg aaaagaatat
     8761 ccatgatatt taccagttag agcttagtca aaaagatgcc aatatgcgag ccttgcaggc
     8821 gcaaatcaat cctcatttta tgtataatac gctggagttc ttgcgcatgt atgcagttat
     8881 gcagagtcaa gatgagttgg cagatatcat ttatgaattc agtagtctct tgcgtaacaa
     8941 tatttccgac gaaagagaga ccctcctcaa acaggaatta gaattttgcc gtaaatacag
     9001 ctatctctgc atggttcgct atcccaagtc cattgcctat ggtttcaaga tagatccaga
     9061 gttagagaat atgaagattc ccaagtttac cttgcaaccg ctggtagaaa actatttcgc
     9121 gcatggtgtt gaccacaggc ggacagataa tgtgattagc atcaaggctc ttaaacagga
     9181 tggttttgtg gaaattttgg tggtcgataa tggtagagga atgtcggctg aaaagttggc
     9241 aaatatccga gaaaaattaa gtcagagata ttttgaacac caagccagct acagtgatca
     9301 aaggcagtct atcgggattg tcaatgtaca cgagcgtttt gtgctctatt ttggagaccg
     9361 ctatgccatt actatagagt ctgcagagca agccggtgtt cagtatcgta ttacaattca
     9421 agatgagtag aaagggagaa aatgtataaa gtattattag tagatgatga gtacatggtg
     9481 acagaaggtc tgaagcgttt gattcccttt gataagtggg atatggaggt tgtcgcaaca
     9541 gccagtcatg ccgatgaagc tctagaatat gttcaggaaa atcctgtcga tgtcatcatt
     9601 tccgatgtca atatgccaga caaaacaggg cttgatatga ttcgggagat gaaagagatc
     9661 ttaccagatg ctgcctatat cctgctctca ggttatcagg agtttgatta tgtaaaaaga
     9721 gcaatgaacc ttagtgtggt ggactatttg gtcaagcctg ttgataaggt agagctggga
     9781 aatctgctgg agaagattgc aggtcagctc ggcgagagag ggaagaaaag tcagactctt
     9841 agtcaagaat tagacgaggc tggatttgtt agttatttag gggataagga gaattggtgg
     9901 ataggtctat ccaaggaaaa acaaggttcc ttcaccattc cctactatgt cttgggccaa
     9961 gactggcaga ttttcatttc tggccaacct ctagatggtt tagtcgttac accttttgaa
    10021 gctccttatc aagaacactt tgaacgctgg aagctgaatg ctgagaaaac cctcttttac
    10081 ggttctgtaa atttgcagca gtctgagagt ctctttgcct attacgaacc gatttatagg
    10141 gttatcattc agggaaatct caatcaaatc gtagaagagt taaatctctt ggagaaggta
    10201 gttcttgaaa atacgccgcg tgttccgatt actaaacagc tttttattca gtttgtcatg
    10261 gatgttttcc atttatttga acatctcaaa gctgatgacc tgacagacat cgtcaaaacc
    10321 attcatgcta ttcaatcctt cgatgaattg gtttcttata tcaaggaaac tctgatcagc
    10381 tttttcggtc aataccgtat gaatgaaaat gtggtcagtg tgctggaagt cattggtcgt
    10441 gattaccaaa aagagctttc cctcaaggat atcagtaagg ctctctttat caatcctgtt
    10501 tatctagggc agttgattaa gcgtgaaacc gattcgactt ttgcagagtt actaaacaaa
    10561 caacgtatta aggctgccca acaacttttg ctttcaacta gtgacagcat cgaagatatt
    10621 tgttatgctg ttggttacag taaccttgga tatttctata aagttttccg aaaattgtgc
    10681 ggaaaatcgc caaaagccta ccgaaaacag gtagaaacta tactataaga tttgtattcc
    10741 tttacaaaag gtgctataat attatcagga ggttctatca tgaaaaagaa accaatttat
    10801 ctatgggtct tgctaatctt gtctgccctt atttcagttc cgtctctgtt tggaattgtg
    10861 agtcccttgc ctagtaaaga agcccttcgt gctgctcaga aacaagttgc aggggtcaat
    10921 gctcagcaat tagaagacca gcttaattat acctatagag tagcagaagc atctcattct
    10981 atttttaatg ttgctttgat tgtgctatct actattttag tggtcgtagc gattgtcttc
    11041 cttgttcgta aaaatttgca atatgcaaac tatacttacg ttggctatgt tttgttagct
    11101 attattggtt cgatttatgg ctatgttggt ttacaagacg ctgtgcagtt ggttcaagat
    11161 gagagcatgc gtttgacagt gagtattggt tcaaaagctg ttagcatttt ctatatcgtc
    11221 atcaatgttc tcttcctagc ccttgtcttc tataagatgt ggcgacaaca gaaagccttg
    11281 gcagaagaag aggaaacaga agagcttacc taagtattga caaaaaagaa ctatcaagat
    11341 acaatcttgg tagttgtttt ttgattatag ataaaatcat ggaggtacat atgaagacaa
    11401 tttctttagt ttatattagt ttgagtggca acactgaaag ttttgtgacg cgcttgaaag
    11461 actatctctt gtcccagtac aaagggattg aggttcaaaa gattcatatc aaggatttgg
    11521 tcaaggaagg caaaaatttc tatgaaatgg accatcccta tgtcgctttt ttgccgacct
    11581 atctcgaagg tgggaatggc gtggataacg gagatgttga gattttgacg acaccggtgg
    11641 gagattttat tgcctatggt aacaatgcta gtaagtgttt tggtgtggtt gggtcaggaa
    11701 atcgtaactt taataaccaa tactgcctaa cagccaagca atacagtcaa cgctttggct
    11761 tccctgtatt ggctgacttt gaaatgcgag gcatgctgga agatatcaaa catgtcgcag
    11821 ctattatcgc agatttgtat gagttggaaa aggagaatta atactcaatg aaaatcaaag
    11881 agcaaactag gaagctagtc gcaggttgct caaagcacag ctttgaggtt gcagatagag
    11941 ctgacgtggt ttgaagagat tctcgaatag tataaagttc ttataagatg tggttgaagt
    12001 tgttcaactg ttttttgagt ataaacagtc tttaagaacg taaaaaagca taagttcagg
    12061 tcttcaaaac cttgttctta tgctttttat catagaaata tttgctgaat tttctcttga
    12121 aatgaaacct tatcttcatc tcgcgcttgt cccttaccct gcttttccga ttgcgagtgc
    12181 gtagataaag aagatggcga agccaaagag gaaaatcaat cccgcaatgg caaggtgttt
    12241 gagccaagaa ggaagatttt tgttttcacg tgttaccaag gcgtaattca aaagagcaaa
    12301 gaaaggtgtt gtcaggaaag agccaatcat ggcaaagcgg agcatggttg aaacctgacc
    12361 agcgaagaac ttgataatga cgataccgat gatagcagtg atggtcatcc agatgttcaa
    12421 agatttacga ttgtcctctt tttgactgat tagcagtcgg agagattcct gattaacgcg
    12481 agaatagcca tcgataacag ttataactgt tccaaagata cagaggaagg caataaaggt
    12541 aatcaagtaa cgggaccatt cgccaagaac agaggcatac atgcccacga attgagagat
    12601 gtatttggct gaagcagctt caaccgcctg ccctgtagga tactgaatca gtgctcccag
    12661 tgccacaaag aagacggcta ggatagctgt tccaatataa ccagtgttaa agtcaaacag
    12721 agcgtcttct gtgttaaagt tgacggtctt tctcttttca gctgaccaaa gtgaattgat
    12781 ggctgaaatt tcaataggag ccggcatcca tcctaggagg gagacgatga agggcagagt
    12841 tgccatttgc caaggtgtct tctcgacaaa atcagaactg tattctggat gcttgaccgc
    12901 cgcaatgata actgcaagaa cagtcgcaat ggttaaggca gacataatcc atttgaccat
    12961 gccgtctaaa agtttgtagc ctccaaagag tagcatagcc caaatgattg caacgagaat
    13021 gagggaccac tgagtaatgc taagtccaat cattgggaag gcactggcga tgatagctga
    13081 gcacagaatg gcaacaccag ccgtgttgac catagccgaa aagacattga gaataaagaa
    13141 aatccagaga tagagttttc ctttttcggc ataaccttca accaaagtct ttccagtatc
    13201 agctgtgtat tcagcaccaa aacggaaaaa tggatattta aagacattgg ctaagatgac
    13261 caagagaagt agagaccaac cgtaagaacc gccagcttga gttgaggata caatgtggga
    13321 acctccaaca gcggcagttg ccattaggat tccaggtccc attgctttta gcttgcttgc
    13381 ccaggttgat tgatttaagg aaatagcttg cgacatgata aatactcctt tttgaatttt
    13441 cagaataatc tgtatatgca atctatattc tacaaaaaat tttggaaaaa tgcaagaata
    13501 ttttgaaaaa agatagaaaa tttacaaaga aaatctgaaa taactgttat gatatagcag
    13561 attgaaacta gaatagtaca cttttgcttc taaaacattg ttagaaatcg atttgactgt
    13621 cctgattgat ttatcctgtt cttatttcat ttcactatag taaggtgcag caggataaag
    13681 caaaaccgag aagtttcttt ctcggttttg cttattatga ggttcctatt ttctatgctc
    13741 caagagttga ttgatgtgat ctactttttt agcctctctt ttatagagaa tagcccagat
    13801 gatgagatag acaatcgcaa actcgataat gagctggagg tagaaaatcc agtggaaggg
    13861 gaaccaacca gcaagagttg ctagtgggac aaagccagcc agcataagga agaaatgagt
    13921 cagagtggca cgaagcatgc tccagtcacg gctgaataag cggttgccaa agttgaagag
    13981 cataccgatg gctgcccaga taagtgtgca gtagagcaag accagggcac cgtgaacctg
    14041 atgctgatcc atcacttggc cgatgagaga gtagggattt agtggtgcgt aggtatttgg
    14101 tgcataaatg agtgaaaaga ggatggagag gatgaggccg ataagaacac cggcagctgc
    14161 atcgtgaaat acttgttttt tcatagttct aatttctcct tgatggtttt tagataacgg
    14221 cgtgaagagt aggtgaagct ttcgtttttc aagaaaattt ctaccagacc gtttggcgtg
    14281 agcttgaggt gagagatgga atcgatattg atgatttctg attgggaaat ttggataaaa
    14341 ttgcttggca agagtttaag aacctgatag agtcgcaaat caatgctgta ggtctgactc
    14401 gcggtttctg ctagaacctt ccgattctcg atatagaagc gctgaatctt gccaatctca
    14461 actagataga cctgatcatc gatttttcct ttgatttttt ctctttggtc cagattttct
    14521 gcgaactcga tgactttctg gactttttcg gtttcttgag gtgcttggac aatcagcttt
    14581 tcctcctcgt aagtctcact aatctgtagt tctactttca taaatttctc tccttgtttt
    14641 tcatacaaaa ttaatctcac ttcttgtaca cctttattaa tactcttcaa aaatctcttc
    14701 aaaccacgtc agcgtcgtct tgccgtagga tagttgttga ctttgtcagt tttatctaca
    14761 acctcaaaac agtgttttga gctgtctgcg tctagctttc tagtttgctc tttgattttt
    14821 attgagtata ccactatttt actccctctg gcaagggact ttgtctatgt ggagggattg
    14881 ggctcctatg tggtggagtt tttctgttct ttctgaaata tggtataata gcactaatta
    14941 atttctagga aaatagatac agaaaggggc tgaaagatgt ctcatattat tgaattgcca
    15001 gagatgctgg caaaccaaat cgcagctggg gaggtcattg aacgtcctgc cagtgtggtt
    15061 aaagagttgg tagaaaatgc cattgacgcg ggctctagtc agattatcat tgagattgag
    15121 gaagctggtc tcaagaaggt tcaaatcacg gataacggtc atggaattgc ccacgatgag
    15181 gtggagttgg ccctgcgtcg ccatgcgacc agtaagataa aaaatcaagc agatctcttt
    15241 cggattcgga cgcttggttt tcgtggtgaa gccttgcctt ctattgcgtc tgttagtgtc
    15301 ttgactctgt taacggcggt ggatggtgct agtcatggaa ccaagttagt cgcgcgtggg
    15361 ggtgaagttg aggaagtcat cccagcgact agtcctgtgg gaaccaaggt ttgtgtggag
    15421 gatctctttt tcaacacgcc tgcccgtctc aagtatatga agagccagca agcggagttg
    15481 tctcatatca ttgatattgt caaccgtctg ggcttggccc atcctgagat ttcttttagc
    15541 ttgattagtg atggcaagga aatgacgcgg acagcaggga ctggtcaatt gcgccaagca
    15601 atcgcaggga tttacggttt ggtcagtgcc aagaagatga ttgaaattga gaactctgac
    15661 ctagatttcg aaatttcagg ttttgtgtct ttacctgagt tgactcgggc taaccgcaat
    15721 tatatcagcc tcttcatcaa tggccgttat atcaagaact tcctgctcaa tcgtgctatt
    15781 ttggatggtt tcggaagcaa gcttatggtt ggacgttttc cactggctgt cattcacatc
    15841 catatcgacc cttatctagc ggatgtcaat gtgcatccaa ctaagcaaga ggtgcggatt
    15901 tccaaggaaa aagaactgat gaccctggtt tcagaagcta ttgcaaatag tctcaaggaa
    15961 caaaccttga ttccagatgc cttggaaaat cttgccaaat cgaccgtgcg caatcgtgag
    16021 aaggtggagc aaactattct cccactcaaa gaaaatacgc tctactatga gaaaactgag
    16081 ccgtcaagac ctagtcaaac tgaagtagct gattatcagg tagaattgac tgatgaaggg
    16141 caggatttga ccctgtttgc caaggaaacc ttggaccgat tgaccaagcc agcaaaactg
    16201 cattttgcag agagaaagcc tgctaactac gaccagctag accatccaga gttagatctt
    16261 gctagcatcg ataaggctta tgacaaactg gagcgagaag aagcatccag cttcccagag
    16321 ttggagtttt tcggacaaat gcacgggact tatctctttg cccaagggcg agatggactt
    16381 tacatcatag atcagcacgc tgctcaggaa cgggtcaagt acgaggagta ccgtgaaagc
    16441 attggcaatg ttgaccagag tcagcagcaa ctcctagtgc cctatatctt tgaatttcct
    16501 gcggatgatg ccctgcgtct caaggaaaga atgcctctct tagaggaagt gggcgtcttt
    16561 ctagcagagt acggagaaaa tcaatttatt ctacgtgaac atcctatttg gatggcagaa
    16621 gaagagattg aatcaggcat ctatgagatg tgcgacatgc tccttttgac caaggaagtt
    16681 tctatcaaga aataccgagc agagctggct atcatgatgt cttgcaagcg atctatcaag
    16741 gccaatcatc gtattgatga tcattcagct agacaactcc tctatcagct ttctcaatgt
    16801 gacaatccct ataactgtcc tcacggacgt cctgttttgg tgcattttac caagtcggat
    16861 atggaaaaga tgttccgacg tattcaggaa aatcacacca gtctccgtga gttggggaaa
    16921 tattaaaagt ataaaaaagt ctgggaaaaa ttttcaaaat cagaaaaacg cataaaatca
    16981 ggtgttcaaa aaccttgatt ttatgcgttt tatcatggaa atagttactt catgttttcc
    17041 taattctttt cgaaactctt tttaaaccac gtcagtttta tcagtaatct caaaacagtg
    17101 ttttgagcta attttgccag ttttgtctgt aacatcgaag ttgtgtttta ccactctgcg
    17161 actggtttcc tagtttgctc tatgattttc acagagtatt aaattgcgat tttgccaagt
    17221 ttctttattc gtctaaaagt agagtctgtt ctatgcgtct aatgtacgaa ttaggttgac
    17281 catttcaata gctccttgtg cacactcaga acccttattt cctgctttgg taccagctcg
    17341 ttctatggct tgttcaattg tatctgtcgt tagcacacca aacataacag gaatttcgct
    17401 atttaaactg atttgggcga ttcccttaga tacctcgcta catacataat cataatgact
    17461 tgtattccct ctaatgacag ctcccaagca gataattgca tcatattttt tactttttgc
    17521 catttttgat gcaatcagtg gtatttcaaa agctcctgga acccaggcta cctctatatc
    17581 tttctcgttt acattctctc ttttgagatt atctagtgct ccagataata attttgaagt
    17641 tataaattca ttaaatctcg ctacaacaat acctatttta atattgtttg ctactaaatt
    17701 accttcataa gtgttcattt atttttcctc catatttaaa atgtgaccca ttcgattttt
    17761 ctttgtttct aaataaaaac tatcgtaagg attggcttct atttcgattg atattctact
    17821 ggaaatggta attccatatt tttctaactg ttcaaccttg tcaggattat ttgtcagtaa
    17881 atgaagtgac tgaagtccca gatctttaag catttgtgct ccaatatgat attctcttaa
    17941 atcaccttca aagcctaatg caagattggc atcaagcgta tccatgcctt gatcttgtaa
    18001 atgataggct tttaatttat tgataagtcc aattcctcgt ccctcctgtc gcaagtaaag
    18061 taagacaccc gaaccattct caacaatcat tttcatagct ttatcgaatt gctgtccaca
    18121 atcgcaacgt aaagagccta aaacatctcc tgttaaacat tcggagtgga cccgacataa
    18181 tacattggct tcatcctcta tgtttcccat aataagagca agatgatgtt ccccatttag
    18241 tttatctata tagctaattg ctttgaaatt accgtatcta gtaggcatat tgacagttga
    18301 aactcgttct atcagctgat catatacttt tctatattct tgtaattctt tgatggtaat
    18361 tagtggaatg ttgtgtttct tcgagaactg aattaaatca tctgttctca tcattttgcc
    18421 atcatgattc attatttcac aacataggcc acactctttt agtccagcta attttaataa
    18481 atcaacagtt gcttctgtgt gtccatttct ttctagaaca ccaccttttt ttgcaattaa
    18541 aggaaacatg tgtcctggcc tgcgaaaatc agagggtgtt atatcttcag ctacacacat
    18601 acgtgcggtc agtcctcttt cctcggcaga aatacctgtg gtcgtttctt tataatcaat
    18661 tgaaactgta aaagcagtct tatgattatc tgtattgttt tcaaccatag gtgaaagcat
    18721 taattgatta gctaaacttt cgctcatagg catacaaatt aatcctttgg cataagtagc
    18781 cataaaatta acattttctg ttgtagctgc ttgtgcagaa caaattaagt ctccttcatt
    18841 ttctctatcc ttgtcgtcta taacaagaac aagtcgtccc ttctgcaatg cttctaatgt
    18901 ttcttgtatt tttcgatatt ccattgactg attatccttt ctgctaaaat ccattttgat
    18961 ataatagttc cttagatatt tctgattttg gagagttatc catcagtttt tgcacatatt
    19021 tacctaagat atcattttca agatttactg tactcccgac ttgtttactt ttaagaatgg
    19081 tttgtttcaa ggtatgaggg ataacagata ctgaaaagtt tactttggag actttagcga
    19141 cagtcagact aatgccgtca attgtaatag atcctttttc aactattaaa tctaaaattt
    19201 ctttttgtgt gttgatttga taccatacag cattatcatc tttttttatt gacgagattt
    19261 ttcctgtacc atcaatgtgt cctgtaacga cgtgaccccc aagtcgaccg ttgatagata
    19321 aggctctttc tagattcacc tcacttccat gttttaatag agtaagagct gttcgactcc
    19381 atgtttcatt cattacatca actgtaaagg attgatgatt gaaatgagta actgtaagac
    19441 agataccatt tactgctata ctatcgccta aatggatatc cgttaatatt tttgaggctt
    19501 taattgatag tttacaatta cgagagtctt tctgtattct ttcaactttt ccgatttctt
    19561 caattattcc tgtgaacatg gataaatcac ttcactttct atgagatagt catttcctat
    19621 ttgagaaaaa gcataaggtt tcaatctaat agcgtcattt ggcaaagaaa tgccttcacc
    19681 tccgacagga aacttggcac tgcctccaaa aatttttggt gcaatatata ttttcagctc
    19741 atcaacaatt tgttgttcca aagcactcca attcattaga ctgccccctt ctagaactag
    19801 gctatcaatc tgcatgtttc ctagatgttg cattaaactc gataagtcta tatgattgcc
    19861 ttttttcttt atggaaagta tttcacagcc atgattttga tatagcttca ttttattttt
    19921 gtcttcagag gaagtggcaa tgtaagtttt aatatcattt gctgttttta cgattttaga
    19981 ggtaagagga gttcgtaaat gtgtatcgca tatgatacgg ataggatttt tcccttcctc
    20041 caatctacat gtcagcaaag gatcgtcttg aataacagta ttgactccca ccataattgc
    20101 actaacatgg tgtcgtaact gatgcacatg ctttcttgct tcttcttcag taatccattt
    20161 ggattgattt gttttagtgg ctatttttcc atccattgac attgcatatt tcataaaaac
    20221 atagggtaca tgctgggtaa tatactttct aaaacttttt attaagttaa gacactcatt
    20281 ttctaaaatt ccaacagtaa cttgaagatt attttcctca agtatcttta ctccttttcc
    20341 agatacaata ggattacagt ctaggcttcc aatgactact cttgtaatac cactatcgat
    20401 tatagcatct atacagggag gtgttttccc gaagtgacaa cagggttcaa gtgttacata
    20461 aagcgtcgct ccgacagggg attctctaca gtttttaaga gcatttctct cagcatgtgg
    20521 gccaccaaaa aactcatgat aaccttgtcc gatgatgtga ttatctttta caataactgc
    20581 gccgaccata ggattgggat tgacgtaacc agcccctttt tgtgccagtt ttattgctaa
    20641 tttcatatat tttgaatcgc tcatctcact acctccaaaa aaaatatacc ttgaataggg
    20701 gactactcaa ggcatacaaa agaaaactta tgcgattaac aaaaatactc tgaaatgaca
    20761 agtaatcatt tcagagcacg caaaaagcac aaatatactt ttatcttctt tcatccagac
    20821 tatactgtcg gctttggaat ttcaccaaat catgcctttc ggctcgtggg ctataccacc
    20881 ggtagggaat tacaccctgc cctgaagata gttattcaat tacagatgat tatagtactt
    20941 aattttgaat atgtcaacag ataaataccg attgtttttg atatactgta tttgtgataa
    21001 tcgattctcg ctcctcggat aaagaaaata tgatatacta gataaacgaa ataagagaga
    21061 aggaatacta tgtacgcata tttaaaagga atcattacca aaattactgc caaatacatt
    21121 gttcttgaaa ccaatggtat tggttatatc ctgcatgtgg ccaatcctta tgcctattca
    21181 ggtcaggtta atcaggagga tcagatttat gtgcatcagg ttgtgcgtga ggacgcccat
    21241 ttgctttatg gatttcgctc agaggatgag aaaaagctct ttcttagtct gatttcggtc
    21301 tctgggattg gtcctgtatc agctcttgct attatcgctg ctgatgacaa tgctggcttg
    21361 gttcaagcca ttgaaaccaa gaacatcacc tacttgacca agttccctaa aattggcaag
    21421 aaaacagccc ggcagatggt gctggacttg gaaggcaagg tagtagttgc aggagatgac
    21481 cttcctgcca aggtcgcagt gcaagcaagt gctgaaaacc aagaattgga agaagctatg
    21541 gaagccatgt tggctctggg ctacaaggca acagagctca agaaaatcaa gaaattcttt
    21601 gaaggaacga cagatacagc tgagaactat atcaagtcgg cccttaaaat gttggtcaaa
    21661 taggagcaga gaatgacaaa acgttgttcg tgggtcaaga tgacaaaccc gctctacatc
    21721 gcctatcatg atgaggagtg gggtcagccc ctccatgatg accaagcatt gtttgagttg
    21781 ttgtgtatgg aaacctatca ggcaggcctg tcttgggaaa cggtactcaa caaacgccaa
    21841 gctttccgag aagcctttca tagctatcaa attcactcag tcgcagagat gactgagact
    21901 gaattggaag ccatgctgga gaatccagct atcattcgaa atagagccaa gctttttgct
    21961 acacgcgcta acgcccaagt ccttctacag ttacaggcag agtacggctc ttttgatgcc
    22021 tatctttggt cttttgttga ggggaaaatt gtcgttaacg atgttcctga ttatcgccaa
    22081 gcgccagcta aaacaccctt atctgagaaa ttagccaaag atctcaaaaa acgaggcttc
    22141 aagttcacag gcccagtcgc cgtattgtct tttctacagg ctgcagggct agttgatgac
    22201 cacgagaatg attgtgagtg gaaaggtctt aaatgatgtc taacaaaaat aagggaattc
    22261 tgatttttgc gattctctat acagtcctct ttgtgtttga tggcgttaaa ttgctggctt
    22321 ctttaatgcc atctgtcatt gcaaattatc ttgtttatgt agttttagct ttatatggct
    22381 ccttcttgtt caaggataga ttgatccaac aatggaagga gattagaaag actaaaagaa
    22441 aattcttctt tggcgtctta acaggatggc tctttctcat tctgatgact gttgtctttg
    22501 aatttgtatc agagatgttg aagcagtttg tgagactaga tggacaaggt ctaaatcagt
    22561 ctaatattca aagtaccttt caagaacaac cactactgat agctgttttt gcttgtgtca
    22621 ttggacctct ggtagaagaa ttatttttcc gtcaggtctt attgcattac ttgcaggaac
    22681 ggttgccagg tttactaagc attattctgg taggacttgt ttttgctctg actcatatgc
    22741 acagtttggc cctatcagag tggattggtg cagttggtta cttaggtgga ggccttgcct
    22801 tttctattat ttatgtgaaa gaaaaagaga atatctacta tcccctactt gttcacatgt
    22861 taagcaacag cctctcctta atcattttag ctatcagtat agtaaaatga aatgagaaca
    22921 ggacaaatcg atttctaaca atgttttaga agtagaggtg tactattcta gtttcaatat
    22981 actgtaatat gtgatgaaaa tgccagtaat gataccgaga aaaaagctga gaaacttttc
    23041 ccagctttat ttgttatagt caaagagaat gacttgttcc tgtgcatcta catgagcatg
    23101 gaccccaaag ggtacaattg ctcttggagt tgcgtggccg acattcagat tatagacaat
    23161 cgggatattg ctgtcaatga tatccaatag tgcctcttta tagtcgtcat ggaaagtttc
    23221 atccataggt tttccgacca agagtccatt gatgaccgcg aatatgccag tgtcctttaa
    23281 agttagcaac atctttttga agtcttctgg cttaggcttt tcttcgcttg tttcgagcaa
    23341 gaggattttc ccttcccagt ctgacaagtc agggaaaagt ttgtattttt ggcagagttc
    23401 cgtgctatct gcgtatcgag agttgtcaaa gatatcgtag agggattcga ggcaaccacc
    23461 gaggattttc ccctcgaact gggcacttcc ttgcaacaag tcaaaacctg tatttgtatg
    23521 actgacacga ggtgttccca gggccgtggg actaaaatca gttcgttcct cataccaaac
    23581 gtcactaggg cggatttctg aaattcttcc cgtctcaatc aattctttaa agtagtgaag
    23641 gctataggct agcatttctt tgtctaattc acaaatgtct gctaaaaagg attgaccata
    23701 aaaagtcttg attcctaatt tatgcaacat gaggtggttc atggttgtat ccgagaagcc
    23761 aagaaaaatt ttttgtttga taaccttttg gagttggtca ttttcaaaaa gataaggtag
    23821 caagcgatag gtatcgtctc caccgatggc acataggatc atgtcgatgc tatcatcaga
    23881 aaaggcatga atcaaatcct ctgcacgagc ttcaggatgg tccttgataa agtctaatcc
    23941 ttttaacgaa tggggcaaaa agatgggatt gagtcccaga tccttgagac gttggatacc
    24001 caagtccact tcgtgtttga caaaatcctc tccgataatg ccactagata aactaacaat
    24061 accaatagta gaaaccatat ctcatcctcc tagaaataga ttgagcctat tttatcacaa
    24121 aatataagag aaagctatgt gggatttcag aagaatactt ttaatactct tcgaaaatct
    24181 cttcaaacca cgtcagtttt atttgcaacc tcaaagctgt gctttgagca acctgcagct
    24241 agcttcctag tttgctcttt gattttcatt gagtataact caaaaaagta agtgaaaaag
    24301 caaccgcacc tgcagttgct tttatcgttt tcttattctt gatagcgtgt tggtcctgca
    24361 cttgcactac ggatattcaa gcgtttcttg agatagaagc gaagggctag gagggctact
    24421 ccaataatag ctagtggcaa tggatccagt actgggttaa ggctagctgg taggaagctt
    24481 gttgcaaaga agacaagcaa ccaaaggaac atagaagtta ggataactag tacagatttc
    24541 cagaaaggtg gacgttgact gcgatccata tctggtccat agtattggta aacaaagtag
    24601 tacatcaagt agaaggcaaa tccaccaacc agtccaacta atagaagagt aatcaatcca
    24661 tagccgaaag cttgatctgc cgcaaagaag gttgtgaggg cgctgacaag ggcaaagagg
    24721 ctagtgatga aaagagctga gtccataatc atcagttttg gatcatcatt ttcttttgga
    24781 tgctcttttt cgtactgctc tttgacagtg aagctatgag cccaatgagt tggtgcgccg
    24841 tatagggaac gggcagttgt acctttagat tgctcctcaa ggatttgggg aatgacttcc
    24901 tcaaaaatag tctggatttc agcgtctgtt ttcccatctt tgatgaattg ttgggtagca
    24961 atgtggacaa actcttggtt tttcttagtt aatttttgta gatcaatttg agacatagga
    25021 actcctctta gaaccatttt ttatggatga gatagagagt gagcgagaca ctcatagcaa
    25081 aggcgataaa gacgattaac cagaaggcat ttggctctcc gtttagggga atttcattat
    25141 ccttaaagtt catcccgtag gcagaaaaga ccatggttgg gatggacatg acgatggtca
    25201 caagggccaa ggttttcatg atgttgttct ggttgttaga aatgatagag gcaaaggtct
    25261 ctgtcataga atgcaagacg tttccataaa tatctgccat ctcgatggcc tgttgggttt
    25321 caatcagggt gtcttcaagc aggtcttcgt cctcaaggta tttcttgata ttgctggttg
    25381 aactggtcaa tttcttaatc acgcgctcat ttgttttgag ggaggccttg aaatagacga
    25441 tagttttttc caattccatg agctcaatca attcttcatt acgagttgat tgatgcagtt
    25501 gactttcgat ttgttcactc ttgcggtcga ttgaacgaag ggctgttagg taaagctctg
    25561 cattgcgata aagaatttga aagataaaac gtgaacgcat gaaggtatag aaattacgca
    25621 atcgacggtt gataaagaca tcaaggacag gtagtggttc caaacacgta gtgataatgg
    25681 tttcctcagt gatgataata ccaagcggga tggttacgta gtaggtgcgg ttatttcttt
    25741 cctccgtgac cggcacgtct acgataatca gggtatactc gtcttcaatg gtaatacgag
    25801 acatttcttc cgcatcgagc ggtgctcgaa ggtcggcaat atcaatatcg aaggtgttgg
    25861 cgatttcgag tgattcattt tgagtcggat tgacgagatt gatccaagta cccggttcaa
    25921 gcgtatcgat ctctttaaat tcagttgttg tagagagaaa aacttgtttc atatccctta
    25981 tcctttctca tttttcagat tttttcacac tgtactatta tactacaaaa tcggcctttt
    26041 gggtaataga atctcacttt ttttggtata atggtaagca ataatggact agaaagaaca
    26101 aagatgcaag ataaaattgt cattcatggg gcgcgtgccc ataatttaaa aaatattgat
    26161 gtggagattc cgcgagacaa gttggttgtc gtgactggct tgtcaggttc agggaagtcc
    26221 agtctggctt ttgatactct ctatgcggag ggacaacgtc gctatgtaga gagtttgtct
    26281 gcctacgctc gtcagttctt gggaaatatg gaaaaaccag atgtagatgc cattgatggt
    26341 ctcagcccag ctatttccat cgaccagaaa acgactagta aaaatcctcg ctcgacggtg
    26401 ggaacgacga ctgaaatcaa tgactatctg cgtctcctct acgcacgtgt ggggacgcct
    26461 tactgtatca acggacatgg agctatcaat gcttcttctg tggagcaaat cgttgataag
    26521 gttttggagt tacctgaacg ccagcgcttg cagatcttgg ctcctgtcat ccgcaagaaa
    26581 aaaggccaac ataagagtgt tatcgagaag gttcagaaag acgggtatgt tcgtgttcgt
    26641 gtggatgggg aagtctatga tgtgaccgaa gtgccagagt tgtctaagag caagcaacac
    26701 aatatcgatg tcgtggttga ccgtattgtt atcaaggagg gcattcgtag ccgtctcttt
    26761 gattccattg aagctgccct tcgtatcgca gaaggttatg tgattatcga caccatggac
    26821 gactctgagt tgttgttctc tgagcattat gcctgtccag tttgtggatt tactgtccca
    26881 gagttagaac ctcgtctctt ctctttcaat gctccctttg gctcttgtag tgagtgtgac
    26941 ggcttgggga ttaagctgga ggtggatact gatttggtag tgccagatgc cagcaaaacc
    27001 ttacatgagg gagcgctggc accttggaat cctatctcat ccaactacta tccaaacatg
    27061 ttagagcagg ccatgaaagt ctttggagtg gctatggata agccttttga ggacctgtca
    27121 gaagaagata agaacttgat tctctacggc tcagatggta aggaattcca tttccattat
    27181 gaaaatgaat ttggtggtgt gcgcgatatc gacattccgt ttgagggagt tatcaataat
    27241 atcaaacgtc gttaccatga aaccaatagc gattacactc gcactcagat gcgtctctac
    27301 atgaatgagc tgacctgcgg aacctgtcaa ggctatcgtc tcaatgacca ggccttgtct
    27361 gtccgtgtgg gcggccagca agggccacat attggagaaa tctcagacct gtctatcgct
    27421 gaccacttgg acttggtgag ccagttaact ttgtctgaaa atgaagccat cattgctcgt
    27481 cccattctca aggaaatcaa ggatcgtttg accttcctta ataatgtggg tcttaactat
    27541 ctaaccctgt cacgttcagc aggaaccctt tcaggtgggg aaagtcagcg cattcgtttg
    27601 gcaacccaga ttggttccaa cctatcaggt gtcctctata tcctagacga gccgtcaatc
    27661 ggtcttcacc agagggacaa tgaccgcctg attgccagtc tgaaaaagat gcgtgacttg
    27721 ggcaatactc ttatcgtggt ggaacacgac gaagatacca tgcgtgaagc tgattatctg
    27781 attgacgttg gtcctggtgc cggtgttttt ggtggtgaga ttgttgcagc aggtacacct
    27841 aagcaagtgg ctcgcaacag caagtctatc acaggtcagt acttgtcagg caaacgtgtc
    27901 atcccagtac cagaagagcg ccgtgtcgga aatggtcgtt ttattgaagt gacaggagcg
    27961 cgtgagaaca acttgcaaaa tgtcacggct cgctttccac taggaaaatt tatcgcagtg
    28021 acaggtgtgt cgggttcagg gaaatcgact ctaatcaaca gcattctcaa aaaagccatt
    28081 gcccagaagc tcaaccgtaa ttcagacaaa cctggtaagt ttaagactat tacagggatt
    28141 gagcatgtcg accgtttgat tgatattgac cagagcccta tcggacggac gccgaggtct
    28201 aacccagcta cctatacagg agtttttgac gatatacgtg acctttttgc tcagacaaat
    28261 gaagccaaga ttcgaggcta caagaagggg cgcttcagtt tcaacgtcaa gggaggtcgc
    28321 tgtgaagctt gctcaggtga cgggattatc aagattgaga tgcacttctt gccagatgtt
    28381 tatgtggctt gtgaagtttg ccacggaacc cgctataaca gtgaaaccct agaagttcac
    28441 tacaaggaaa agaatatttc gcaggtcttg gatatgacgg tcaacgatgc ggtagaattt
    28501 ttccaacaca ttccgaaaat tcaacgcaaa ctccagacca tcaaggatgt aggtctaggc
    28561 tatgtgacct tgggacagcc agctaccacc ctttctgggg gagaagccca acgtatgaag
    28621 ttagctagcg aactccacaa acgctcgaca ggaaaatctt tctacattct ggatgagccg
    28681 acgacagggc ttcatacaga ggacattgct cgcctgctca aggttttagc tcgctttgta
    28741 gacgccggca atacagtcct cgtcatcgag cacaatctgg atgttatcaa gacggcagac
    28801 catatcattg acttgggacc tgagggcggt gtcggtggtg gaaccatcat cgtaacagga
    28861 actccagaag aagtagctgc caacgaagcc agctatacag gacactattt gaaaggaaag
    28921 ttacatcatg aataaacgcg tacaagcatt tctagctaaa atgcaagaaa aagaactaga
    28981 tggtatcatc atcaacaatc ttaaaaacgt ctattatttg actggttttt ggggctcaaa
    29041 cggaacagtc tttatcagcc gtgaccgtca ggtcttagtg acagactctc gctatatcat
    29101 cgcagctaag caagaaacca gtggttttga gattgtggct gatcgtgatg aattggctgt
    29161 cattgcagga attgttaagg acatgaactt gactcgtatc ggttttgaag atgagatttc
    29221 agtgtcttat taccaccgta tgcaggcagc ttttgcaggt ttgaacttgc ttccacaaac
    29281 tcagtttgtg gaaggtcttc gtatgattaa ggatgaggca gagattgcag cgattcgcaa
    29341 ggcttgttct atctcagacc aagctttccg cgatgcgctt gactttatca aaccaggaaa
    29401 aactgaaatt gagattgcca acttccttga tttccgcatg cgtgagttgg gagcatctgg
    29461 cttatctttt gatacgatcc tagctagcgg tatcaattct tctaaacccc atgcccatcc
    29521 aatgcacaaa ccagtggagt tgggagaagc cattaccatg gacttcggct gtctctatga
    29581 ccactatgtc agtgatatga cccggactat ctatctaggg catgttagcg atgagcaggc
    29641 agagatttac aatacggttc taaaagctaa ccaagccttg attgaccaag ctaaggcagg
    29701 cttaggtttc cgtgactttg acaaaatccc tcgtgatatt atcattgagg caggttatgg
    29761 tgactacttt actcacggca ttggccacgg tattggtctg gatatccatg aggaacccta
    29821 ctttagtcag acttctacag aaactattaa gacaggtatg gccttgaccg atgaaccagg
    29881 tatctatatc gaaggcaaat atggcgttcg tatcgaggat gatatcctga ttacagagac
    29941 aggttgtgaa ttattgaccc tagctccaaa agagttgata gtcatttagt tgtttgtcaa
    30001 gaaaaaagta cgaaaatgac gaaaaaagtc aaaaaaaatt aaaaataggt cgcaagtcgg
    30061 atgtttttta tggtataata gactaaactg atagtaacat gtagcgaaag gggtaggtac
    30121 atgattaaaa tttatacagt ctcaagttgt actagttgta aaaaagcaaa aacctggctc
    30181 aatgcccacc agttaagtta taaagaacaa aaccttggta aagaaggaat tacgagagaa
    30241 gaattactgg atattctaac caaaacagat aacggaatag ccagcatcgt ttcgtctaaa
    30301 aatcgctatg ccaaagccct tggagtggat attgaagatt tgagtgtcaa tgaagttctc
    30361 aatctgatta tggaaacacc gagaatttta aagagcccaa tccttgtaga tgaaaaacgc
    30421 ctgcaagttg gctacaagga agacgatatt cgtgccttcc taccacgctc tgtccgtaat
    30481 gtagaaaatg cagaagcacg tttgcgtgca gctctataaa catcaaggct gggagcactt
    30541 cccagtctta ttctatttta atttcaaaaa gaaagaagaa agaaatgaaa aaaatagttc
    30601 ttgttagtct agctttcctt tttgtcctgg ttggttgcgg acagaaaaaa gaaactggac
    30661 cagctacaaa aacagaaaaa gatacgcttc agtcggcatt gccagttatt gaaaatgctg
    30721 agaagaatac agttgtaact aagactttgg tcttgcccaa gtcagatgat ggtagccagc
    30781 agacacaaac aattacttac aaagacaaga cttttttgag tctagctatc caacaaaaac
    30841 gtccagtctc tgatgagttg aagacttata ttgaccaaca tggagtggag gaaactcaaa
    30901 aagctcttct tgaagcggag gagaaggata agtctatcat tgaagctcgt aaattggcag
    30961 gtttcaaact tgaaacaaaa ctattgagcg caacggaact tcaaacaacg actagttttg
    31021 attttcaagt tctggatgtc aagaaggctt cccagttgga acatctgaag aatattggtt
    31081 tggaaaatct tttgaaaaat gaaccaagca aatatatttc agatagattg gcaaatggcg
    31141 cgacagaaca atagaaaatc caaataaata gactgcctga attgtagaag gtaaggaatt
    31201 atgctataat ggtactattc taaggaaaga gggtgttaga atgggattta ctgaagaaac
    31261 agtacgtttt aaattggacg attccaataa aaaagaaatt agcgaaactt tgacagatgt
    31321 ttatgcttcg ttgaacgata agggttacaa cccaattaac caaatcgtag gttacgtatt
    31381 gagtggagac cctgcctacg ttcctcgtta taataatgca cgaaatcaaa tccgtaagta
    31441 tgagcgtgat gaaatcgttg aggaattggt tcgctactac ctcaaaggac aaggagtcga
    31501 tctataacct atgagaatta tgggattgga cgtcggttca aaaacggtag gggtggcgat
    31561 tagcgatccg cttggtttta cagctcaagg gcttgaaatc atccagataa atgaagaaca
    31621 aggccaattt ggttttgacc gcgttaagga attggttgat acttacaagg tggaacgatt
    31681 tgtagtgggc ttgcctaaaa acatgaacaa tacaagtgga ccgcgcgtag aagctagtca
    31741 agcctacgga gcaaagctag aagagttttt tggtttacca gtagactatc aggatgaacg
    31801 cttgacaaca gtggctgctg agcgcatgtt gattgaacaa gcagatatca gtcgcaataa
    31861 gcgcaagaaa gtcattgata agttagcagc tcagctgatt ttacaaaatt atttagatag
    31921 aaaattttaa tataaaggag aggctatgtc acacgatcat aaccacgacc acgaagaacg
    31981 tgaactaatc acactagtag atgagcaagg aaatgaaacc ttgtttgaaa tccttttgac
    32041 aattgatgga aaagaagaat ttggtaaaaa ctatgttctt ctagtaccag ttaacgcaga
    32101 agaagacgaa gacggacaag ttgaaatcca agcttactca ttcattgaaa atgaagatgg
    32161 aacagaaggc gaattgcaac caatcccaga agactcagaa gacgaatgga acatgattga
    32221 agaagtcttc aacagcttta tggaggagtg atacagtctg ggagactgta tcagcccaac
    32281 tccagaaatg gggaagagtt ggaacgtcca gtgaacattt ttaccccaac tcttagaaat
    32341 tgagaagagt tggaacatct agtggatgtt tttagcccat attcacattc atagtagcta
    32401 gttattagct aaccaggtaa gaggtcggga cgaaaatcct ggccttgttt ttattagtaa
    32461 ccatacttta atgcgataat tgattggact tttgtcaagg agatgtgtat gtttgaagta
    32521 gaagaatggc tccatagtcg gattggtttg aattttcgat caggtttggg ccgaatgcag
    32581 caagcggtgg atttgttagg aaatcctgag cagtcttacc ctattatcca cgtaacaggg
    32641 actaatggga aaggatctac cattgctttt atgagggaat tatttatggg gcatggcaaa
    32701 aaagttgcga cctttacctc ccctcatatc gtctctatca atgaccgaat ctgcattaat
    32761 gggcaaccta tagcagacgc agactttatc cgtttgactg atcaggtcaa ggagatggag
    32821 aaaacgcttc tgcaaactcc tgcccagttg tccttttttg aattgctgac cttagttgct
    32881 tttctttatt ttagggagca agaggtggat ttggttttat tagaagtggg aattggtggc
    32941 ttacttgaca cgaccaatgt ggtaactgga gagcttgctg tcatcacctc cattgggctt
    33001 gaccatcaag aaaccttggg tgatagtcta gaagcaattg cagagcagaa agctggtatt
    33061 ttcaaggctg gtaaaaaggc agtgattgcg aaattgcctc cagaagctag acttgtctgt
    33121 cagaaaaaag ccgaatcttt agctgttgac ctttatcagg caggtcaaga tttttcagtg
    33181 ctgaatggtg atttttcaag ctctttacta aatctttcac agctgaacat aggcttagaa
    33241 ggagcctatc agcaggagaa tgcggccttg gcgttgcaaa cttttcttct ttttatggga
    33301 gaaagaaagg aagctattga tgaacaggct gtaagaaagg ccttggaaca gacccattgg
    33361 gctggtcgct tggagcgtat tcgcccacag atttacttgg atggtgctca taacctccct
    33421 gccttgactc gcttggttga gtttatcaaa gaaaaagagc aggaaggcta tcgacctcaa
    33481 atcctctttg gatccttgaa acgtaaggat tatcaaggga tgttgggtta tctgactgaa
    33541 aatttacctc aagtggaact caaaatgacc ggctttgact atcaagggtc tttggacgag
    33601 acagatgtaa caggttacca tgtaattccc tcttaccgag aatttatcag cagtttcgaa
    33661 gaaagggcag acgctcaaga cttgctgttc gttacagggt ctctctattt tatctcagaa
    33721 gtacggggct acctgctgga ccgtgagcag ataaattgac cccctttttt gaacttgtta
    33781 tactagggga attgctggtt agagaaaatt tctctaaatt ggtagcagaa aggaaattca
    33841 tcatgaaatt aaaaagattc acactttctc ttgcttctct agcaagtttt agtctcttag
    33901 tagcttgttc acaaagagct caacaggttc aacagcctgt tgctcagcag gtccaacagc
    33961 ctgctcaaca gaataccaat actgcaaatg caggaggtaa ccaaaatcaa gcggctccag
    34021 tacaaaacca acctgttgct caaccgaccg atattgatgg gacttatact ggtcaggatg
    34081 acggagaccg tatcacttta gtggtaactg gaacgactgg tacatggact gagctcgaat
    34141 ctgacgggga tcagaaagtc aaacaggtta catttgattc agcaaatcaa cgcatgatta
    34201 ttggcgatga tgtcaaaatt tacactgtaa acggtaatca aatcgtcgta gatgatatgg
    34261 atagagaccc atcggaccaa atcgttttaa ctaaataaga ctatgcaagt agaaagggct
    34321 ggatttttca gcctttttac ttttacctag aaaataatca taaatacttg ccttctaccg
    34381 aatacctgcg ttatactagt atcaattact tgtttttagc attcaaacta tcaaggaggg
    34441 gatatgaaat ataggaaatt tcaattattg atgtccaagt atggctttag tctttcgatt
    34501 atgctacttg aactttgtct tgtttttggt ctctttcttt atttaggacg catggctccc
    34561 attttatgga ttactgtcct cattctactg agtatcatca caatcatttc gatagtcaac
    34621 cgtaatacga ctcctgagaa taaggtaacc tggttgttag tagcctttgt gccagtattt
    34681 ggtcccttgc tctatctgat gtttggtgaa aggcgattgt ccaaaaaaga aatcaaacaa
    34741 ctgaagaagc taggctctat gcatttccaa gaagcaaata gccagctact aaaagagaaa
    34801 ttaaaagaaa gtgacaaggc agcttatgga gtcatcaagt ccttattgag tatggatacc
    34861 aatgctgaca tctatgatca aactgcctct acattttttc ctaacggaga agctatgtgg
    34921 aaaaagatgg tagaagatct taaaaaggct gagaaattta ttttcttgga atattacatt
    34981 atagaagaag gtttgatgtg gaatcgcata ctagatatac tagagcaaaa ggtagctcag
    35041 ggtgtagagg ttaagatgct ctatgatgat atcggctgta tggctacttt aacaggagat
    35101 tatgcacatc gacttcgtca gctgggcatc gaggcccata aattcaataa agttattcct
    35161 cgtttgacag tggcttataa taacagagat catagaaaaa tattgattgt tgatggtcag
    35221 atagcctata ctggtggggt caatctggca gatgagtaca ttaaccacgt cgagagattt
    35281 ggttattgga aggatagtgg aattcgctta gacggactag cagtaaaagc cctgacacgc
    35341 ttatttttga ccacttggta cattaatcga ggagaaatta gtgattttga tcaatatcat
    35401 ttagaaaatc attctatccc gagtgacggt ttaaccattc catacggaag tggacccaag
    35461 ccaatttttc gagcgcaggt agggaaaaaa gtttatcaga gtttaatcaa tcaagcaaca
    35521 gaatcggtct atattacgac accttatttg attatagatt atgatttaac agagacaatc
    35581 aaaaatgcag ctatgagagg ggtcgatgtt cgaattatca ccccttacat accagataag
    35641 aagttcattc agttagtcac gagaggagct tatcccgacc ttctttctgc tggtgttcgg
    35701 atttatgagt atagtccagg ttttattcat agtaagcaga tgttggtaga cgaagatttt
    35761 gcggtggtgg ggacaatcaa tctcgactac cggagcttgg tacaccatta tgaaaatgca
    35821 gtcttactct ataaaactcc ttctataagg gaaatcgccc gagattttcg aaatatattt
    35881 gcagattctc aggaagtcta tcctcattct atcaaaacga gctggtatca aaagcttgta
    35941 aaagaaatcg cccagctatt cgcccctatc ttataagaaa tctagaactt aggatacaaa
    36001 ccagacctat ttttcttgtc ttttactaat agaaagaaag aggaggggaa ttcatgctaa
    36061 ctaaggaaga agtgaatgat atgattgagt tcaaacagac acatttatac cgctttcggg
    36121 aaattgaaac ctttgtgaaa ctatgcaaaa aatcactcaa acagccatcg caagctgaca
    36181 atcctaggac tttttgatat actaagacag ataaattgaa caggagaaac gatatgagtg
    36241 tgtatggtag agtagaagaa gttcataagg agaatcgtga acctctagaa taccaaatcg
    36301 aacaagaatc gcatcatcgt gaatcaagtc gtcttccttt ggtgaaaatt ttactatgga
    36361 gtacgcttgt aacggggata actctaggag taccgctatt actcgactta atgagtgcac
    36421 aagaagtgca ggatttttat gcaggttggg ggcttcatca gacagggaag atttacagcg
    36481 actattatgg aagtcaaggt ttgctttatt atttgctgac ttacgtgagt cagggcggat
    36541 ttttctttgc catctttgag tggttagcct tggtagcagg aggatttttc ctttttagat
    36601 cagcggacac cttgacagag caaggagacc aagctggaca tctggtgact attttttaca
    36661 tgctagttac aggtcttgct tttggtggag gctatgcgac tcttttagcg cttcctttct
    36721 tattcgcagc ctttagttta gttgcggctt acctaagcaa tccaagccat gataagggat
    36781 ttgtacggat tgggctagct ttggcaggcg gatttttctt tgctccctta tcatcgctcc
    36841 tgtttattgc tgtagtgagt ttaggcttgt tggtctttaa ccttgggcat agacgctttg
    36901 cgcatgggtt ttatcagttt cttgcagtgg ctttaggttt ttcacttgtc ttttatccaa
    36961 ctgcctacta tagtgctgca acaggaagtt ttggggatgc gattagtggt attcgttatc
    37021 ctattgacag tattcgcttt gattttactt ctaaaatttt agagaatatg tttttttatg
    37081 gcttgttgtc ccttggtttg ggatttgtgg tttgtatctt tttaggtctc tttcaatcca
    37141 aaccctttaa actatacgtc atttcggttc ctgcaagtct tgtggtaatt ttaggtttga
    37201 ttttactttt cttttcacaa gagcctctgc acgcttctta tttgatggtc gtcttccctg
    37261 ttttcctact tttattggta accaatatta agagtcaaca gagggggcgt agtgctagaa
    37321 gaagccgaag agaaacgcca gttagcctat ggagtcgttt cttcaaagga aatctatatc
    37381 tgctagtttt tgggtttgtc tatcttttgt ctgttccttt tttgatgaag tttgtccttt
    37441 atccagtacc ttatcaagaa cgtaatcgtc ttgctgattt ggtaaaagag gagacaaata
    37501 cggaagatgc tatctatgca tgggatgata ctgcgactct ttatcgtaag agtgagcgct
    37561 tgtcgccatc ggcgattttg tccccgttgc actatacagc aactgaggaa aatcgtaata
    37621 agttacttaa tgacttgaaa gaaaaacaac ctaaggtgat tgtggtaaat gacaaggtgg
    37681 tagtctggtc tgaagtggaa acacttttaa aagaaaatta ccaacaagta aagactgatt
    37741 actcagagtt taaagtctat aaaattaaat aaccaaatca atatcttgtg tatttttaaa
    37801 aattttagga tttttaacac aagatattga tttttctttt tagagtggta taatactttt
    37861 tagaaagaac attttagaaa agagcatgcg tatgattgca ctagaagaaa aaattacaat
    37921 tttgccaact ctcttcgtcg agaaacgaga tgggagacgt gttgtatttg atgtggacaa
    37981 gattgacaag gctctccaca aggcggctga caaggttatg gatgtgacac ccctggttga
    38041 aaaacgcctc aatgatctga ctgagcgaat tattacagaa attcatagtc gctttccaca
    38101 gggaattaag atttacgaaa ttcaaaatat cgtagaacat gaactccttg aagccaaaga
    38161 atatgcgctg gctgaggagt atattactta tcggacacag agggattttg agcgctcaaa
    38221 agcgacggat atcaacttta gtattcataa acttctcaac aaagaccaga cagttgtcaa
    38281 tgaaaatgct aataaagaca gtgatgtctt taacactcag cgtgatttga cagcagggat
    38341 tgttgggaaa tcaatcggac tgcaaatgct tcctaagcac gtagccaatg cccaccaaaa
    38401 gggggatatc cactatcacg atttggacta cagtccctat acccctatga ccaactgctg
    38461 tttgattgat tttaagggta tgttggaaaa tggttttaag attggaaatg cagaggtaga
    38521 gagtcccaag tctatccaga ctgcgacagc acagatttct caaatcattg ccaacgttgc
    38581 ttctagccag tacggtggct gttcagctga ccgtatcgat gaaattttgg cgccttatgc
    38641 agagaagaat tatcaaaaac atctcaaaga tgcagaagag tgggtattgc ctgaaaaacg
    38701 ggaagattac gcttggaaga aaacgcaaaa ggacatctac gatgccatgc aatctcttga
    38761 gtatgaaatc aatactctct tcacttcaaa tggacaaaca ccttttactt cgttaggttt
    38821 tggtctggga accagtcgtt ttgaacgaga aattcaaaaa gctattttaa acattcgcat
    38881 caagggtctt ggttcagaac accgtacggc tatctttcct aaacttattt tcactctgaa
    38941 aagaggcctt aatttagagg aaggaactcc caactacgac atcaagcagt tggctcttga
    39001 gtgtgcaacc aaacggatgt atccagatgt tttatcttac gataagattg ttgacttgac
    39061 aggatccttc aaggtgccta tgggttgccg ttctttcctc caaggatgga aggatgaaaa
    39121 tggtgtagaa gtcaattcag gtcgcatgaa tctgggtgtt gtgacggtta atctgcctcg
    39181 tattgctctt gagtctgaag gtgatatgaa taagttctgg gaaatcttca acgagcgaat
    39241 gaatatcgca gaagatgctc ttgtttaccg tgtcgaacgc actaaagagg cgacaccagc
    39301 aaatgctcct attctttatc agtacggtgc ttttggccat cgtctaggta aagaagaaag
    39361 tgttgaccag ctctttaaga atcgtcgtgc taccgtttcg ctgggctata tcggcttgta
    39421 tgaagtagcg acagttttct ttggtaacag ctgggaaagt aatccagatg ctaaggaatt
    39481 cacgctagac atcattcacg atatgaaacg ccgtgtagaa gagtggtcag accaatatgg
    39541 ctaccatttc tctatctact caacaccatc cgaaagtctg acagaccgtt tctgtcgact
    39601 agatatagac aagtttggct ctattcctga tatcacagac aaggaatact acaccaactc
    39661 tttccactac gatgttcgta aaaatccaac accgtttgaa aaattggact ttgagaaagt
    39721 ctatccagaa gcaggtgcgt caggtggttt catccattat tgtgagtatc cagtccttca
    39781 gcaaaatcca aaggccttgg aagctgtctg ggattatgct tatgaccgtg taggctatct
    39841 aggcaccaat actccgattg accgttgcta caagtgtgac tttgaagggg attttgaacc
    39901 aactgagaga gggtttgctt gtccaaactg tggcaatagc gaccctaaaa cagtagatgt
    39961 ggtgaagcga acttgtggct acctaggtaa tcctcaagca agaccgatgg tcaacggccg
    40021 tcacaaggaa atcgctgcgc gtgtcaaaca tatgaatggt tcaacgatta aaatagctgg
    40081 gcatcaagta acaaattaga aagaaatgaa atgggaaaat atcaactaga cgataagggg
    40141 cgcgcacaag tgacccgtta tcacgagaaa cactctaaag gtggagctgg taagaaagaa
    40201 cgcttgctta gcttcagaga acaattttta aacaagaaca agaaaaaata aaagtgagag
    40261 ccagctctcg cttttctcat agtgggaggt aaggatggaa ttacgcagac caagattagc
    40321 ggataagaaa gctgttttag atatgatgac agagtttgaa aaatttcagt cgcctcacga
    40381 cggcggtttc tgggatacag agaactttgt gtatgaagac tggttagaaa gcaatcagga
    40441 acaggaaatg gggattaatc tgcctgaagg atgggttcct gcaattcagt tagtggcttt
    40501 ttctgagaaa ggtcaagcag ttggatttct taatctccgg ttgcgcctca gtaactttct
    40561 actagaagaa ggtggccaca ttggctactc cattcgtcca tctgaaagag gcaagggtta
    40621 tgcaaaagag actctccgtc agggcttgca agttgctaag gaaaagaaca tcaagaaagc
    40681 tctggtgacc tgtagcgtga ataatcctgc tagcagagca gtcattctag caaatggtgg
    40741 aatatttgag gatgctcgca atggagtcga gcgttattgg atagaggtag cgaatgaata
    40801 atccaaaacc acaagaatgg aaaagcgagg aacttagtca aggtcgtatc attgactaca
    40861 aggcctttaa ctttgtggac ggcgaaggcg tgcgtaactc tctctatgta tcaggctgta
    40921 tgtttcactg cgagggatgt tataatgttg caacttggtc ttttaatgct ggcattccct
    40981 atacagcaga attagaagag cagatcatgg cagatcttgc tcagccctat gttcaaggtt
    41041 tgactttgtt gggaggggag ccttttctta atactgggat tctcttgcca cttgttaagc
    41101 ggattcggaa ggaattgcca gacaaggaca tctggtcctg gaccggctac acttgggaag
    41161 aaatgatgtt ggaaactcca gataaactgg aattcttgtc actgattgac attcttgtcg
    41221 atggaagata tgatcgaact aagagaaatc ttatgctcca gtttcgaggt tcatctaacc
    41281 aacgaattat cgatgtgcaa aaatcgctca aaagtgggca agtagtgatt tgggacaagc
    41341 tcaatgacgg aaaagaaagc tatgaacagg tgaagagaga atgaagaaaa aatgaagaaa
    41401 aaagacttag tagaccaact agtctcagag atcgagacgg ggaaagtcag gacactggga
    41461 atatacggtc atggagcttc aggtaaatca acctttgcac aggaattgta ccaagcttta
    41521 gattctacta cagtaaattt gctagaaaca gatccctata tcacctccgg acgctatttg
    41581 gtagtaccca aggacgcgcc gaatcaaaag gtgacagcca gtctgccagt ggcgcatgaa
    41641 ctggagagtt tgcagagaga tatccttgcc ttgcaggcgg gtatggatgt cttgacaatt
    41701 gaagaacctt ggaaggctag tgaggtcttg tctggagcca aaccaatttt gattgtcgaa
    41761 gggatgtctg ttggttttct acccaaggaa ctctttgaaa aaaccatctg tttctacacg
    41821 gatgaggaga ccgaattaaa gcgacgcctt gctagagata cgactgtgag aaatcgctat
    41881 gcatccttta tattggctag ccatcagatg agacgggagc agtatctgcg atactataaa
    41941 gaaactgagt ctaaggcgga tatcttagtg gaccaatcag aagataaatt tgatgtcaag
    42001 aggacttaac ttatgtatag aagaaatata gaagaaaatc cctaatttta gaaagaaaaa
    42061 gtaggaaaac agtttcatcc caaaaaaacg aaaaaaccta acaaatccct tgcaatcgca
    42121 ggggatttgt gttattctat tatggtgctg taaattacag ccttagtttt gatgcaagag
    42181 gttgcgacac gctcggttgc attgccacgc aacaccgcgt cggttttctt gtggagctag
    42241 cctattatct taaatagacg aaaaggagaa aaagatggca aacaaaaaaa tccgtatccg
    42301 tttgaaagct tacgaacacc gtacgcttga cacagcggct gcaaaaatcg tagaatcagc
    42361 tactcgtaca ggtgcacaag ttgcgggtcc aatcccactt ccaactgaac gtagcctcta
    42421 cacaatcatt cgtgcgactc acaaatacaa agactctcgc gaacaatttg aaatgcgtac
    42481 acacaaacgt ttgatcgata tcgttaaccc aactcaaaaa acagttgatg ccttgatgaa
    42541 attggatctt ccaagtggtg taaacgtaga aatcaaactt taatctaaaa tataaaagag
    42601 cagaggctgg tgtttcaatc taattgaaca cgggctaaac tcggtgtgaa aaagataaac
    42661 ttcctcgcgt ctgctagaca ctgtgtcagt ttcctatttt cactttgagt ttgacgccct
    42721 ttgtatctta gacttgagca taaaaaacgc tcgttaaaaa ctttttgaat aaaaaatata
    42781 gaaaaggaac tattttctca tgacaaaagg aatcttaggg aaaaaagtgg gaatgactca
    42841 aatcttcact gaagctggcg aattgatccc tgtaacagtt attgaagcaa ctccaaacgt
    42901 tgttcttcaa gttaaaactg ttgaaacaga cggatacaac gctatccaag ttggtttcga
    42961 tgacaaacgc gaagtattga gcaacaaacc tgctaaagga catgtagcga aagctaacac
    43021 ggctcctaag cgcttcattc gtgaattcaa aaacgttgaa ggcttggaag ttggtgctga
    43081 aattacagtt gaaacattcg cagctggaga cgttgttgac gtaactggta cttctaaagg
    43141 taaaggtttc caaggtgtta tcaaacgcca cggacaatca cgtggaccaa tggctcacgg
    43201 ttctcgttac caccgtcgtc caggttctat gggacctgtt gcacctaacc gcgtattcaa
    43261 aggtaaaaac cttgcagggc gtatgggtgg cgaccgcgta acaattcaaa accttgaagt
    43321 tgtacaagtt gttccagaaa agaacgttat ccttatcaaa ggtaacgtac caggtgctaa
    43381 gaaatctctt atcactatca aatcagcagt taaagctggt aaataataaa gaaaggggaa
    43441 atcagtcaca atggcaaacg taacattatt tgaccaaact ggtaaagaag ctggccaagt
    43501 tgttcttagc gatgcagtat ttggtatcga accaaatgaa tcagttgtgt ttgatgtaat
    43561 catcagccaa cgcgcaagcc ttcgtcaagg aacacacgct gttaaaaacc gctctgcagt
    43621 atcaggtggt ggacgcaaac catggcgtca aaaaggaact ggacgtgctc gtcaaggttc
    43681 tatccgctca ccacaatggc gtggtggtgg tgttgtcttc ggaccaactc cacgttcata
    43741 cggctacaaa cttccacaaa aagttcgtcg cctagctctt aaatcagttt actctgaaaa
    43801 agttgctgaa aacaaattcg tagctgtaga cgctctttca tttacagctc caaaaactgc
    43861 tgaatttgca aaagttcttg cagcattgag catcgattct aaagttcttg ttatccttga
    43921 agaaggaaat gaattcgcag ctctttcagc tcgtaacctt ccaaacgtga aagttgcaac
    43981 tgctacaact gcaagtgttc ttgacatcgc aaatagcgac aaacttcttg tcacacaagc
    44041 agctatctct aaaatcgagg aggttcttgc ataatgaatt tgtatgatgt tatcaaaaaa
    44101 cctgtcatca ctgaaagctc aatggctcaa cttgaagcag ggaaatatgt atttgaagtt
    44161 gacactcgtg cacacaaact tttgatcaag caagctgttg aagctgcttt cgaaggtgtt
    44221 aaagttgcca atgttaacac aatcaacgta aaaccaaaag ctaaacgtgt tggacgttac
    44281 actggtttta ctaacaaaac taaaaaagct atcatcacac ttacagctga ttctaaagca
    44341 atcgagttgt ttgctgctga agctgaataa tctaaggagg aaatatcgtg ggaattcgtg
    44401 tttataaacc aacaacaaac ggtcgccgta atatgacttc tttggatttc gctgaaatca
    44461 caacaagcac tcctgaaaaa tcattgcttg ttgcattgaa gagcaaggct ggtcgtaaca
    44521 acaacggtcg tatcacagtt cgtcaccaag gtggtggaca caaacgtttt taccgtttgg
    44581 ttgacttcaa acgtaataaa gacaacgttg aagcagttgt taaaacaatc gagtacgatc
    44641 caaaccgttc tgcaaacatc gctcttgtac actacactga cggtgtgaaa gcatacatca
    44701 tcgctccaaa aggtcttgaa gtaggtcaac gtatcgtttc aggtccagaa gcagatatca
    44761 aagtcggaaa cgctcttcca cttgctaaca tcccagttgg tactttgatt cacaacatcg
    44821 agttgaaacc aggtcgtggt ggtgaattgg tacgtgctgc tggtgcatct gctcaagtat
    44881 tgggttctga aggtaaatat gttcttgttc gtcttcaatc aggtgaagtt cgtatgattc
    44941 ttggaacttg ccgtgctaca gttggtgttg tcggaaacga acaacatgga cttgtaaacc
    45001 ttggtaaagc aggacgtagc cgttggaaag gtatccgccc aacagttcgt ggttctgtaa
    45061 tgaaccctaa cgatcaccca cacggtggtg gtgaaggtaa agcaccagtt ggtcgtaaag
    45121 caccatctac tccatggggc aaacctgctc ttggtcttaa aactcgtaac aagaaagcga
    45181 aatctgacaa acttatcgtt cgtcgtcgca acgagaaata atattaaact agtcgcttaa
    45241 gcaactagta aatccgccag ctcggtagcg ctccatagga gtgcaagccg ctgtggtaca
    45301 acatttaaag gagaaaatat aaaaatggga cgcagtctta aaaaaggacc tttcgtcgat
    45361 gagcatttga tgaaaaaagt tgaagctcaa gctaacgacg aaaagaaaaa agttattaaa
    45421 acttggtcac gtcgttcaac gatcttccca agtttcattg gttacactat tgcagtttat
    45481 gacggacgta aacacgtacc tgtttacatc caagaagaca tggtaggcca caaacttggt
    45541 gaatttgcac caactcgtac ttacaaaggt cacgctgcag acgacaagaa aacacgtaga
    45601 aaataaggag aacataaatg gcagaaatta cttcagctaa agcaatggct cgtacagtac
    45661 gtgtttcacc tcgtaaatca cgtcttgttc ttgataacat ccgtggtaaa agcgtagccg
    45721 atgcaatcgc aatcttgaca ttcactccaa acaaagctgc tgaaatcatc ttgaaagttt
    45781 tgaactcagc tgtagctaac gctgaaaaca actttggttt ggataaagct aatttggtag
    45841 tatctgaagc attcgcaaac gaaggaccaa ctatgaaacg tttccgtcca cgtgcgaaag
    45901 gttcagcttc accaatcaac aaacgtacag ctcacatcac tgtagctgtt gcagaaaaat
    45961 aaggaggtaa aatcgtgggt caaaaagtac atccaattgg tatgcgtgtc ggcatcatcc
    46021 gtgattggga tgccaaatgg tatgctgaaa aagaatacgc ggattacctt catgaagatc
    46081 ttgcaatccg taaattcgtt caaaaagaac ttgctgacgc agcagtttca actattgaaa
    46141 tcgaacgcgc agtaaacaaa gttaacgttt cacttcacac tgctaaacca ggtatggtta
    46201 tcggtaaagg tggtgctaac gttgatgcac tccgtgcaaa acttaacaaa ttgactggaa
    46261 aacaagtaca catcaacatc atcgaaatca aacaacctga tttggatgct caccttgtag
    46321 gtgaaggaat tgctcgtcaa ttggagcaac gtgttgcttt ccgtcgtgca caaaaacaag
    46381 caatccaacg tgcaatgcgt gctggagcta aaggaatcaa aactcaagta tcaggtcgtt
    46441 tgaacggtgc agatatcgcc cgtgctgaag gatactctga aggaactgtt ccgcttcaca
    46501 cacttcgtgc agatatcgat tacgcttggg aagaagcaga tactacatac ggtaaacttg
    46561 gtgttaaagt atggatctac cgtggtgaag ttcttccagc tcgtaaaaac actaaaggag
    46621 gtaaataacc aatgttagta cctaaacgtg ttaaacaccg tcgtgagttc cgtggaaaaa
    46681 tgcgcggtga agcaaaaggt ggaaaagaag tagcattcgg tgaatacggt cttcaagcta
    46741 caactagcca ctggatcact aaccgccaaa tcgaagctgc tcgtatcgcc atgactcgtt
    46801 acatgaaacg tggtggtaaa gtttggatta aaatcttccc acacaaatca tacactgcta
    46861 aagctatcgg tgtgcgtatg ggatctggta aaggggcacc tgaaggttgg gtagcaccag
    46921 ttaaacgtgg taaagtgatg ttcgaaatcg ctggtgtatc tgaagagatt gcacgtgaag
    46981 cgcttcgact tgctagccac aaattgccag ttaaatgtaa attcgtaaaa cgtgaagcag
    47041 aataaggaga aggcatgaaa cttaatgaag taaaagaatt tgttaaagaa cttcgtggtc
    47101 tttctcaaga agaactcgcg aagcgcgaaa acgaattgaa aaaagaattg tttgaacttc
    47161 gtttccaagc tgctactggt caattggaac aaacagctcg cttgaaagaa gttaaaaaac
    47221 aaatcgctcg tatcaaaaca gttcaatctg aagcgaaata atagactagg gaaggagaaa
    47281 tttcaatgga acgcaataat cgtaaagttc ttgttggacg tgttgtatct gacaaaatgg
    47341 acaagacaat cacagttgta gttgaaacaa aacgtaacca cccagtctat ggtaaacgta
    47401 ttaactactc taaaaaatac aaagctcatg atgaaaacaa tgttgccaaa gaaggcgata
    47461 tcgtacgtat catggaaact cgcccgcttt cagctacaaa acgtttccgt cttgtagaag
    47521 ttgttgaaga agcggtcatc atctaatcaa acctgaaagg agaaaactga aatgattcaa
    47581 acagaaactc gtttgaaagt cgcagacaac agcggtgctc gcgaaatctt gactatcaaa
    47641 gttcttggtg gttcaggacg taaatttgca aacatcggtg atgttatcgt ggcatctgta
    47701 aaacaagcta ctcctggtgg tgcggttaaa aaaggtgacg ttgttaaagc agttatcgtt
    47761 cgtactaaat caggtgctcg tcgtgctgat ggttcataca tcaaatttga cgaaaacgca
    47821 gcagttatca tccgtgaaga caaaactcct cgcggaacac gtatctttgg cccagttgca
    47881 cgtgaattgc gtgaaggtgg cttcatgaag atcgtgtcac ttgctccaga agtactttaa
    47941 tttttaggaa caaactagtc ccctagcttc aagctagggt gcccttatgg gcgtaagaaa
    48001 aatcaaggag aaacctaatg tttgtaaaaa aaggcgacaa agttcgcgta atcgctggta
    48061 aagataaggg aacagaagct gttgtcctta ctgcccttcc aaaagtaaac aaagttatcg
    48121 ttgaaggtgt taacattgtt aagaaacacc aacgtccaac taacgagctt cctcaaggtg
    48181 gtatcatcga gaaagaagca gctatccacg tatcaaacgt tcaagttttg gacaaaaatg
    48241 gtgtagctgg tcgtgttggt tacaaatttg tagacggtaa aaaagttcgc tacaacaaaa
    48301 aatcaggcga agtgcttgat taatcacgaa ggaaaggaga agtataatgg caaatcgttt
    48361 aaaagaaaaa tatcttaatg aagtagttcc tgctttgaca gaacaattca actactcatc
    48421 agtgatggct gtgcctaaag tagataagat tgttttgaac atgggtgttg gtgaagctgt
    48481 atcaaacgct aaaagccttg aaaaagctgc tgaagaattg gcacttatct caggtcaaaa
    48541 accacttatc actaaagcta aaaaatcaat cgccggcttc cgtcttcgtg aaggtgttgc
    48601 gatcggtgca aaagttaccc ttcgtggtga acgtatgtac gaattcttgg ataaattggt
    48661 atcagtttca cttccacgtg tacgtgactt ccacggtgtt ccaacaaaat catttgatgg
    48721 acgcgggaac tacacacttg gtgtgaaaga acaattaatc ttcccagaaa tcaacttcga
    48781 tgacgttgac aaaactcgtg gtcttgacat cgttatcgta acaactgcta acactgacga
    48841 agagtcacgt gcattgctta caggccttgg aatgcctttt gcaaaataat ataggaggta
    48901 aatctaatgg ctaaaaaatc aatggtagct agagaggcta aacgccaaaa aattgttgac
    48961 cgttatgctg aaaaacgtgc tgcattaaag gcggcagggg actacgaagg tttatctaaa
    49021 ttacctcgca acgcttcacc gactcgttta cataatcgtt gtagagttac ggggcgccca
    49081 cattcagttt accgcaaatt tggtctgagt cgtatcgctt ttcgcgaact tgcgcataaa
    49141 ggtcaaattc ctggtgtaac aaaagcatct tggtaattta agatatcaag ggcgtcaaaa
    49201 ctccaagtaa aaataggaaa cttgacgaag aaactaaagt ttctaggaaa gtttatcttt
    49261 ttcacacaga gtttagcccg ggttcaattg ggcttgccaa tttgaacacg agctacagct
    49321 ttggcaaaaa agaccaattt gctttggagc attgcttctg cattaaattg tctatttttg
    49381 ctcgtgctgt tacgctcttt gtatcatgta ttaactagca agtgcaactt gcaaactact
    49441 agtaagagga gaaaaacaaa atggttatga ctgacccaat cgcagacttc ctaactcgta
    49501 ttcgtaatgc taaccaagct aaacacgaag tacttgaagt acctgcatca aacatcaaaa
    49561 aagggattgc tgaaatcctt aaacgcgaag gttttgtaaa aaacgttgaa atcatcgaag
    49621 atgacaaaca aggcgtcatc cgtgtatttc ttaaatacgg accaaatggt gaaaaagtta
    49681 tcactaactt gaaacgtgtt tctaaaccag gacttcgtgt ctacaaaaaa cgtgaagacc
    49741 ttccaaaagt tcttaacgga cttggaattg ccatcctttc aacttctgaa ggtttgctta
    49801 ctgataaaga agcacgccaa aagaatgttg gtggtgaggt tatcgcttac gtttggtaaa
    49861 atcaagatac aaagctcgta aagaacaaag caaaattagg aagttggaga agtttgttta
    49921 caaacaagcc aacttatcta ttttgcacag ttcttagagc gtgttcagtt cagctcttga
    49981 actaaataag tatctgaacc ccgtgaaaac tggccgtttt ggcctgacaa tttaacagga
    50041 gaaaataaac atgtcacgta ttggtaataa agttatcgtg ttgcctgctg gtgttgaact
    50101 cgctaacaat gacaacgttg taactgtaaa aggacctaaa ggagaactta ctcgtgagtt
    50161 ctcaaaagat attgaaatcc gtgtggaagg tactgaagta actcttcacc gtccaaacga
    50221 ttcaaaagaa atgaaaacta tccacggaac tactcgtgcc cttttgaaca acatggttgt
    50281 tggtgtatca gaaggattca agaaagaact tgaaatgcgt ggggttggtt accgtgcaca
    50341 gcttcaagga tctaaacttg ttttggctgt tggtaaatct catccagacg aagttgaagc
    50401 tccagaagga attacttttg aacttccaaa cccaacaaca atcgttgtta gcggaatttc
    50461 aaaagaagta gttggtcaaa cagctgctta cgtacgtagc cttcgttcac cagaaccata
    50521 taaaggtaaa ggtatccgtt acgttggtga attcgttcgc cgtaaagaag gtaaaacagg
    50581 taaataatgt tgagtggttg atcatcaacc accaacctat tttccaactt tgtgcatagc
    50641 acacgattta aaactaaaga ggtgaaaact gtgatttcaa aaccagataa aaacaaactc
    50701 cgccaaaaac gccaccgtcg cgttcgcgga aaactctctg gaactgctga tcgcccacgt
    50761 ttgaacgtat tccgttctaa tacaggcatc tacgctcaag tgattgatga cgtagcgggt
    50821 gtaacgctcg caagtgcttc aactcttgat aaagaagttt caaaaggaac taaaactgaa
    50881 caagccgttg ctgtcggtaa actcgttgca gaacgtgcaa acgctaaagg tatttcagaa
    50941 gtggtgttcg accgcggtgg atatctatat cacggacgtg tgaaagcttt ggctgatgca
    51001 gctcgtgaaa acggattgaa attctaatag gaggacacta gaaaatggca tttaaagaca
    51061 atgcagttga attagaagaa cgcgtagttg ctgtcaaccg tgttacaaaa gttgttaaag
    51121 gtggacgtcg tcttcgtttc gcagctcttg ttgttgttgg tgaccacaat ggtcgcgtag
    51181 gatttggtac tggtaaagct caagaagttc cagaagcaat ccgtaaagca gtagatgatg
    51241 ctaagaaaaa cttgatcgaa gttcctatgg ttggaacaac aatcccacac gaagttcttt
    51301 cagaattcgg tggagctaaa gtattgttga aacctgctgt agaaggttct ggagttgccg
    51361 ctggtggtgc agttcgtgcc gttgtggaat tggcaggtgt ggcagatatt acatctaaat
    51421 cacttggttc taacactcca atcaacattg ttcgtgcaac tgttgaaggt ttgaaacaat
    51481 tgaaacgcgc tgaagaaatt gctgcccttc gtggtatttc agtttctgat ttggcataag
    51541 aaaggggata aaatggctca aattaaaatt actttgacta agtctccaat cggacgcatt
    51601 ccatcacaac gtaaaactgt tgtagcactt ggacttggca aattgaacag ctctgttatt
    51661 aaagaagata acgctgctat ccgtggtatg attacagcag tatctcactt agtaacagtt
    51721 gaagaagtaa actaatgaag ttttagggga tgtgcactgt accatcccct aaaactagat
    51781 atagtcatct atgatgacat cgtataggcg agttgatggg ggagacaacc ttttctccct
    51841 tatcggcgct agcattttac aaaagaggag aaaataaaaa tgaaacttca tgaattgaaa
    51901 cctgcagaag gttctcgtaa agtacgtaac cgcgttggtc gtggtacttc atcaggtaac
    51961 ggtaaaacat ctggtcgtgg tcaaaaaggt caaaaagctc gtagcggtgg cggagttcgc
    52021 cttggttttg aaggtggaca aactccattg ttccgtcgtc ttccaaaacg tggattcact
    52081 aacatcaacg ctaaagaata cgcaattgtg aaccttgacc aattgaacgt ctttgaagat
    52141 ggtgctgaag taactccagt tgttcttatc gaagcaggaa ttgttaaagc tgaaaagtca
    52201 ggtattaaaa ttcttggtaa cggtgagttg actaagaaat tgactgtgaa agcagctaaa
    52261 ttctctaaat cagctgaaga agctatcact gctaaaggtg gttcagtaga agtcatctaa
    52321 gagaggtgac ctatgttttt taaattatta agagaagctc ttaaagtcaa gcaggttcga
    52381 tcaaaaattt tatttacaat ttttatcgtt ttggtctttc gtatcggaac tagcattaca
    52441 gttcctggtg tgaatgccaa tagcttgaat gctttaagtg gattatcctt cttaaacatg
    52501 ttgagcttgg tgtcggggaa tgccctaaaa aacttttcga tttttgccct aggagttagt
    52561 ccctatatca ccgcttctat tgttgtccaa ctcttgcaaa tggatatttt acccaagttt
    52621 gtagagtggg gtaaacaagg ggaagtaggt cgaagaaaat tgaatcaagc tactcgttat
    52681 attgctctag ttctcgcttt tgtgcaatct atcgggatta cagctggttt taataccttg
    52741 gctggagctc aattgattaa aactgcttta actccacaag tttttctgac gattggtatc
    52801 atcttaacag ctggtagtat gattgtcact tggttgggtg agcaaattac agataaggga
    52861 tacggaaacg gtgtttccat gattatcttt gccgggattg tttcctcaat tccagagatg
    52921 attcagggca tctatgtgga ctactttgtg aacgtcccaa gtagccgtat cacttcatct
    52981 atcattttcg taatcatttt gattattact gtattgttga ttatttactt tacaacttat
    53041 gttcaacaag cagaatacaa aattccaatc caatatacta aggttgcaca aggtgctcca
    53101 tctagctctt accttccgtt aaaggtaaac cctgctggag ttatccctgt tatctttgcc
    53161 agttcgatta ctgcagcgcc tgcggctatt cttcagtttt tgagtgccac aggtcatgat
    53221 tgggcttggg taagggtagc acaagagatg ttggcaacta cttctccaac tggtattgcc
    53281 atgtatgctt tgttgattat tctctttaca ttcttctata cgtttgtaca gattaatcct
    53341 gaaaaagcag cagagagcct acaaaagagt ggtgcctata tccatggagt tcgtcctggt
    53401 aaaggtacag aagaatatat gtctaaactt cttcgtcgtc ttgcaactgt tggttccctc
    53461 ttccttggtg tgatttccat tttaccgatt gcagctaaag atgtatttgg tctttctgat
    53521 gttgttgcct ttggtggaac aagtctcttg atcattatct ctacaggtat cgaaggaatc
    53581 aagcaattgg aaggttacct attgaaacgt aagtatgttg gtttcatgga cagaacagaa
    53641 taaaagtatt tactgaatca gtaaatactg agggagtgga ggtttaaact ctgacatttg
    53701 taagagttgg atctcccctc ttctattttg tttttaaata ggggtgaaaa gactttttgc
    53761 ttctatttaa aaataaaata aggagatcaa atcatgaatc ttttgattat gggcttacct
    53821 ggtgcaggta agggaactca agcagcaaaa atcgtagaac aattccatgt tgcacatatc
    53881 tcaacaggtg atatgttccg cgctgcaatg gcaaatcaaa ctgaaatggg tgttcttgct
    53941 aagtcatata ttgacaaggg tgaattggtt cctgacgaag ttacaaatgg aatcgtaaaa
    54001 gaacgccttt cacaagatga tattaaagaa acaggattct tattggatgg ttacccacgt
    54061 acaattgaac aagctcatgc cttggacaaa acattggctg aacttggcat tgaactagaa
    54121 ggtattatca atattgaagt gaaccctgac agcctcttgg aacgtttgag tggccgtatc
    54181 atccaccgcg taactggaga aactttccac aaggtcttta acccaccagt tgactataaa
    54241 gaagaagatt actaccaacg tgaagatgat aagcctgaga cagtaaaacg tcgtttggat
    54301 gttaatattg ctcaaggaga accaatcatt gctcactacc gtgccaaagg tttggttcat
    54361 gacatcgaag gtaatcaaga tatcaatgat gtcttctcag atattgaaaa agtattgaca
    54421 aatttgaaat aaagcgtttt tcgcacttgc aaaaatccgc tacaaatgtt atactgagat
    54481 agtctgactt ataattgttg tctctgtgtc tagaggcatc gaatcgaaat ttatggaggt
    54541 gcttttgcgt ggcaaaagac gatgtgattg aagttgaagg caaagtagtt gatacaatgc
    54601 cgaatgcaat gtttacggtt gaacttgaaa atggacatca gattttagca acagtttctg
    54661 gtaaaattcg taaaaactat attcgtattt tagcgggaga tcgtgttact gtcgaaatga
    54721 gtccatatga cttgacacgt ggacgtatca cttaccgctt taaataatcg aaaaacttgg
    54781 agggataaga aatgaaagta agaccatcgg tcaaaccaat ttgcgaatac tgtaaagtta
    54841 ttcgtcgtaa tggtcgtgtt atggtaattt gcccagcaaa tccaaaacac aaacaacgtc
    54901 aaggataaga tagaaaggag aaaacatggc tcgtattgct ggagttgata ttccaaatga
    54961 caaacgcgta gtaatctcat tgacttatgt ttatggtatc ggacttgcaa catctaagaa
    55021 aattttggct gctgctggaa tctcagaaga tgttcgtgta cgtgatctta catcagatca
    55081 agaagatgct atccgtcgtg aagtggatgc aatcaaagtt gaaggtgacc ttcgtcgtga
    55141 agtaaacttg aacatcaaac gtttgatgga aatcggttca taccgtggta tccgtcaccg
    55201 tcgtggactt cctgtccgtg gacaaaacac taaaaacaac gctcgcactc gtaaaggtaa
    55261 agctgttgcg attgctggta agaaaaaata atataggagg taaaagtctt ggctaaacca
    55321 acacgtaaac gtcgtgtgaa aaagaatatc gaatctggta ttgctcatat tcacgctaca
    55381 tttaataaca ctattgttat gattactgat gtgcatggta atgcaattgc ttggtcatca
    55441 gctggtgctc ttggtttcaa aggttctcgt aaatctacac cattcgctgc tcaaatggct
    55501 tctgaagctg ctgctaaatc tgcacaagaa cacggtctta aatcagttga agttactgta
    55561 aaaggtccag gttctggtcg tgagtcagct attcgtgcgc ttgctgccgc tggtcttgaa
    55621 gtaacagcaa ttcgtgatgt gactccagtg ccacacaatg gtgctcgtcc tccaaaacgt
    55681 cgccgtgtat aatcatcgca ttacactgct tttcgtttaa gagggagtaa ctaaatgatc
    55741 gagtttgaaa aaccaaatat aacaaaaatt gatgaaaata aagattatgg caagtttgta
    55801 atcgaaccac ttgaacgtgg ctacggtaca actcttggta actctcttcg tcgtgtactt
    55861 ctagcttctc taccaggagc agctgtgaca tctatcaaca ttgatggtgt gttacatgag
    55921 tttgacacag ttccaggtgt tcgtgaagac gtgatgcaaa tcattctgaa cattaaagga
    55981 attgcagtga aatcgtacgt tgaagacgaa aaaatcatcg aactggatgt tgaaggtcct
    56041 gctgaagtaa cagctggtga cattttgaca gatagcgata ttgaaattgt aaatccagat
    56101 cattatctct ttacaatcgg tgaaggttct tctctaaaag cgactatgac tgttaacagt
    56161 ggtcgtggat atgtacctgc tgatgaaaat aaaaaggata atgcaccagt tggaacactt
    56221 gctgtagatt ctatttatac accagttaca aaagtcaact atcaagtgga acctgctcgt
    56281 gtaggtagca atgatggttt cgacaaatta acccttgaaa tcttgacaaa tggaacaatt
    56341 attccagaag atgctttagg gctttcagca cgtattttga cagaacatct tgatttgttt
    56401 acaaatctta ctgagattgc taagtcaact gaagtgatga aagaagctga tactgaatct
    56461 gacgaccgta ttttagatcg tacgattgag gaactggact tgtctgtgcg ttcatacaac
    56521 tgtttaaaac gtgccggtat caatactgtg catgatttga cagaaaaatc tgaagcagag
    56581 atgatgaaag tacgaaatct tggacgcaag agtttggaag aagtgaaact caaactcatt
    56641 gatttgggtc ttggattaaa agataaataa aggaggaata catggcttac cgtaaactag
    56701 gacgcactag ctcacaacgt aaagcaatgc ttcgcgattt gacaactgac cttttgatca
    56761 acgaatcaat cgtgacaact gaagctcgtg ctaaagaaat ccgtaaaact gttgaaaaaa
    56821 tgattactct aggtaaacgt ggtgatttgc atgcacgtcg tcaagcagct gctttcgtac
    56881 gtaatgaaat cgcatctgaa aactatgatg aagcaactga taagtacact tctactacag
    56941 cacttcaaaa attgttctca gaaatcgcac ctcgttatgc tgaacgtaac ggtggataca
    57001 ctcgtatcct taaaactgaa ccacgtcgtg gtgatgcagc gccaatggcg atcatcgaat
    57061 tagtataaaa tcatcaattt tgttgagtgt tatgatgatg gagtcttgtg ctcttagtct
    57121 agctctggtc taccgctagg atttcggtcc tagcgggaac actcatcata agttgggata
    57181 gtagacgctt gtttacgaaa ttgttttttt cttaagaaca acttcgtaag caggcgtttt
    57241 tgagtatttt cgttagaatt atgctatact atttgaaaag aatcctgttt aatgttaagg
    57301 tttcttattt taagaagaat tggagtttac ttatgaaagc cattataact gttgttggta
    57361 aagataaatc tggaattgtt gcaggtgttt ctggtaaaat tgcagaatta ggattgaata
    57421 ttgacgatat ctctcaaact gtcttggatg aatattttac gatgatggct gttgtatcta
    57481 gtgatgaaaa gcaagatttt acctatcttc gtaatgaatt tgaagctttt gggcaaactt
    57541 tgaatgtaaa aatcaatatt cagagtgcag cgattttcga agctatgtat aatatctagg
    57601 aggttatcat ggatattaga caagttactg aaaccatcgc catgattgag gagcaaaatt
    57661 tcgatatcag aaccattacc atggggattt ctcttttgga ttgtatcgat ccagatatca
    57721 atcgtgctgc ggagaaaatc tatcaaaaaa ttacgacaaa ggcggctaat ttagtagctg
    57781 ttggtgatga aattgcggct gagttgggaa ttcctatcgt taataagcgt gtatcggtga
    57841 cacctatttc tctgattggg gcagcgacag atgcgacgga ctacgtggtt ctggcaaaag
    57901 cgcttgataa ggctgcgaaa gagattggtg tggactttat tggtggtttt tctgccttag
    57961 tacaaaaagg ttatcaaaag ggagatgaga ttctcatcaa ttccattcct cgcgctttga
    58021 ctgagacgga taaggtctgc tcgtcagtca atatcggctc aaccaagtct ggtattaata
    58081 tgacggctgt ggcagatatg ggacgaatta tcaaggaaac ggcaaatctt tcagatatgg
    58141 gagcggccaa gttggttgta ttcgctaatg ctgttgagga caatccattt atggcgggtg
    58201 cctttcatgg tgttggggaa gcagatgtta tcatcaatgt cggagtttct ggtcctggtg
    58261 tggtgaaacg tgctttggaa aaagttcgtg gacagagctt tgatgtagta gccgaaacag
    58321 ttaagaaaac tgcctttaaa atcactcgta tcggtcaatt ggttggtcaa atggccagtg
    58381 agagactggg tgtggagttt ggtattgtgg acttgagttt ggcaccaacc cctgcggttg
    58441 gagactctgt ggcacgtgtc cttgaggaaa tggggctaga aacagttggc acgcatggaa
    58501 cgacagctgc cttggccctc ttgaacgacc aagttaaaaa gggtggagtg atggcctgta
    58561 atcaggtcgg tggtctatct ggtgccttta tccctgtttc tgaggatgaa ggaatgattg
    58621 ctgcagtgca aaatggctct cttaatttag aaaaactaga agctatgacg gctatctgtt
    58681 ctgttggatt ggatatgatt gccatcccag aagatacgcc tgctgaaact attgcggcta
    58741 tgattgcgga tgaagcagca atcggtgtta tcaacatgaa aacaacagct gttcgtatca
    58801 ttcccaaagg aagagaaggc gatatgattg agtttggtgg tctattagga actgcacccg
    58861 ttatgaaggt taatggggct tcgtctgtcg acttcatctc tcgcggtgga caaatcccag
    58921 caccaattca tagttttaaa aattaagaaa ataggagaaa ttttaagttc tatttaagat
    58981 tagatgtgta tactataatc attaaataaa gacctcctaa tattatttga aacagataac
    59041 actgaattag tttgaatttg attttcatct aatatcttta tttaatgaac tcctaaactt
    59101 tttcataata atctccttca aaagtcgcct gtatgggtgg cttttatttt atcattcatg
    59161 atataataga agcaaacgga ggacggaaaa tggtaaaagt acgattgtat ttgatacgtc
    59221 atggcaagac catgtttaac acgattggtc gcgcgcaagg ttggagcgat actcccttaa
    59281 ctgctgaagg tgaacgaggg attcaagagt taggaattgg tttgcgagaa tctgatctac
    59341 agtttgagcg cgcttattcg agtgattctg gtcgtaccat tcagaccatg ggaattatcc
    59401 ttgaagaact tggcttgcag gggaaaatcc cttatcgcat ggacaagcgt atcagagaat
    59461 ggtgtttcgg tagttttgat ggagcctatg atggcgatct tttcatgggc attattcctc
    59521 gtatctttaa tgtggaccac gttcaccaat tgtcttatgc tgaactggct gagggcttgg
    59581 tagaggtcga tacagctggt tgggctgaag gctgggaaaa actcagtggc cgaatcaagg
    59641 aaggctttga aatgattgca aaagaaatgg aagatcaagg tggaggtaac gcccttgttg
    59701 tcagccatgg aatgactatt ggaaccattg tttatctgat taatggcatg catccgcatg
    59761 gtctagataa tggtagcgtg acgattcttg aatatgagga cggtcagttt agggttgaag
    59821 ttgtcggtga ccgtagttac cgagagctag gacgtgagaa gatggaagaa ggctctattt
    59881 aatcagtcta gacttgcttg ccatgagcta gggatttgat aagaatatca agataagaaa
    59941 aaacagccga gggtactcct ttcggctgtt tttgatgtgg aaaactaaag tgtaatgcta
    60001 ttgcttttag agattttcat aaacaagagc aaggaaccta ctgttagaac agtcaggata
    60061 gttgacaagg ctgcggctac accgtaattt cctctgagaa cctctgtata aatagctaca
    60121 gtcattgttc ttgttttgac attgtagagg aggatagaag tagagagttc tgaaatcagt
    60181 gtgacccaag ataggatggc tccagaaata atatccgata gcatcattgg agttgtaatc
    60241 ttagcaaaga tattgagacg actacttcct aagctttcag cagcttcttc aatacttggt
    60301 gctatttgtt gtaagctagc aacagatgag cgaatagtat aaggtaattt tctggcagat
    60361 agagacataa tcaagatgaa agcagtccct gtaatcataa gaaatccact tccaaataga
    60421 ccagagaaat gaaggcaatc cctagaacgg ttcctggtac aatataaggt accatactga
    60481 ggctgtcaat taagtttgta aacaaattcc gttttctaac ggctaggtag gagataaatg
    60541 tcgcaaatag aacaactaga actaaggcaa tcaaagggat acgaatggta ttgaaaatag
    60601 cagatcccat acgatggaaa gctaccttgt aactgtttgg agaataacct ttaacagata
    60661 ccatacctga tgtttttagg aaagaggtat aaattaagta gatttgaggt aaaacagaga
    60721 taaagataat tccgtagact gttgcataaa tggcagctat ttttcctttt gtagtttttt
    60781 taggctcaat tggatggagc agattcatgc tgaaactgta gcggtttgca atgtgttttt
    60841 ggataaggaa aattgccaag gcaatgataa tcgccataat tgcaaaagca gaatttcctc
    60901 caacctcgct aataaattgg gtataaatca ggacagggaa agtccgatat ccttcgccaa
    60961 tcaacatagg cgttccaaag tctgagaatg ctctcataaa tacaagcaag gagctgctag
    61021 taaggttgga actaggagag gtaaaacaac cgttacgata cgcttaaatc cgaaggaccc
    61081 ccatgctttc agctgcttca agtagagaat tgtcaatact gttcattgtt ccagcaacat
    61141 atagaaatac cagtgggaat agttgcagtg taaagacaag tacaattcct ttgaatccat
    61201 aaatatcgat agctggaaga tgaagggcat ttgtcaaaaa tttagtgatg accccatttc
    61261 gtcctagcaa gagaacccag gagtaggctc ctacgaaagg agctgacatg gaagcaatga
    61321 taatcaatat ttgtagaaat ttctccccct tgaagtcata catagagaag agataagcta
    61381 atagggttcc tacaactaag gaagtgacag tagcggtaat ggaaaccttg aaactgttga
    61441 ctagtgtctc agagtagtag actttactaa agaaagtgac aaaattagct agtgagaatt
    61501 atccttcatg tataagtgct tacttgagca cggtaatgat aggataaacg agaaagacaa
    61561 gataggtaag aaagatgaag aaagaggagg ctgtccaaat atttagtttt ttacattcca
    61621 tggttgactc cttttatcag gttttgggaa ccatctgcag aaaagatgtt taatttttgc
    61681 gtattgattc gtagacgaat acgattgtct ttttgtagat cttcttcaaa agttgattct
    61741 tcactaactt gaatttttga ggcaaaacct gtctcaatga aatactccgt atttagtcca
    61801 agatagacgc tatcgctaat agttccttca atatctccag attcatcttt gataaactct
    61861 tcgggacgaa tgcttacatg aatagcttgc tcctcaacct gatcaagagc tggcattcga
    61921 agggcatagc catctgaaaa gacgatataa gcgccgtcgc tccgtttttc aagattggca
    61981 gggataatat ttgtgcgtcc gataaaggtt gccacaaact cattagctgg tttatgatag
    62041 agttcttttg gtcggccgat ttgttggatc accccatctt tcataacagc aatttgatct
    62101 gaaatagcca tggcttcttc ttggtcgtgg gttacataaa cagttgtaat tcccacttcg
    62161 tgttggattt ctcggatggc ttgacgcata tccaagcgaa gtttggcctc cagattacta
    62221 agtggctcgt ccatgaggag aacacttgga ttaaccgcta aggcgcatgc caaggtgaca
    62281 cgttgttgtt gtccaccact gagtttatcg ggctttcgat ccgcatattg agcaatttgc
    62341 atgagttcaa gatacttgtt ggtctgttga atcaattctt cttttggaac cttcttttgc
    62401 ttaagaccaa aagcaacgtt gtctcggaca gtcaaatgtg ggaaaatagc gtagttttgg
    62461 aaaaccatcc cgatattgcg tttgctgggt tccatattat tgatttttgt atcatcgaag
    62521 taaaattctc catctttgat actgttgaaa cctgcaatca tacgaagaag ggtcgttttc
    62581 ccacatcctg aaggtccaag aagggtaaag agacttcctt ttggaattgt aatgttcaaa
    62641 ttctcaataa cagggacatc gtggtagatt ttttggcgtt aataattttg atctcactca
    62701 tagtgaacct tttttactgt ttagattgga tatctgtaaa gacttcgttg tatttcttaa
    62761 cgatatctga tttattcttg atgacataat cataatcttc agtgagtgtt ttgattttgt
    62821 caattggttt catgttttcg cttgttttag catttttacg aacaggacgg ttagtagtgg
    62881 ttgtaccaag tgtatcttgt acttcttgag agataataaa atcgataaat ttcttgtcat
    62941 tttccatatt tttagctttt ttaacgatag cagcactagc aggtaggaag acggttcctt
    63001 cttttggata gactacttta atgttagctc cgtcatttaa gagtttaact gctggatcct
    63061 cataagagag accaacagcc atttctccat caacgactgc tttatagaca ccagatgaac
    63121 ttgaaccgat tttatagtgt attgaaacta gaatagtaca cctctacttc taaaacattg
    63181 ttagaaatcg atttgactgt cctgattaat ttgtcctgtt cttatttcat ttcactatgc
    63241 catcaataag tgtgaaaaga tcttttacat aagaccaagc cttatcatct ttgtaaccac
    63301 cttgagcttg tagcatattt gttaattgag caaaggcgct agaagagttt gctgggtcag
    63361 cagttgcgat ttttcctttt agttcaggtt tgagaaggtc gctatatcct tcgatgttca
    63421 tgcctttagt taaatcaggg ttgacgatta aaacactacc atctagtgta taaggagtag
    63481 agaagccagt tgtgttttga tattctttga taacattatc attttctttt gaaatatagt
    63541 tttcaaagag ttctccgtgg gtagcatatt gtgtataaga accaccaaag ataacatcag
    63601 ctacaggaac ttctttttct gactctagtt ttttgaaaag ttctccagta ccagcttgaa
    63661 tcagttctat tttgatacca tatttttctt caaaggcagg aatagttgct ccaattaagc
    63721 cttctgagtt tggtgaataa acgactagcg aaccaccgtc tcctttatca gatgaactgt
    63781 catcggcaga ttcattagaa gaacaagcag cataatacat ctatttcttt ttcatgatgg
    63841 atatctccgt tgtgttattt aagtttattt taaaacaatg taagcgtttt taaaacctac
    63901 aattctattc tatagtgtat tgaatctata acagtacact ttgactgcta aaatatttct
    63961 ataaattaat ttgactttcc tgatagagat gttcacatct tatttcaatt cactatatta
    64021 gagtaaaatt ctctacaaaa agaagaatag cctatttgac tattcttccg agtgatttca
    64081 atttctttgg ggaaatatgg agatactttt taaatacttt ggcaaaatat ttatagtctg
    64141 aaaatccaac ttggtcagag atagcgctta aaggggagtt gggagattca gccatcttat
    64201 ctatagcttg tttcaggcga tattgtaaga tatattcatt tagagtcatg gggaagtctt
    64261 ctttgataac cttatataga tgcttgttat ctgcaaatag ctagagcatt tcaaggaaat
    64321 aaactagaaa taacaattaa tatggtggtt cagaaatacc ttttgataat caataagatc
    64381 ttcaggatga agtgcgttga ttccatccat ttcatatttc cgatttaata aacgatattt
    64441 gttttcacca aattgatgaa aagggagtag ttgaacttgg tcgatattta atgagttaaa
    64501 tagagtagcg aatttttctg catcctctaa actattgtta aaattaggaa taactgggat
    64561 tcttaaaacg atagttttat tttgagaaaa agcataatga atgtttttaa taatcatttg
    64621 attaaaaacc ccagtcactt ttttatgttt tatagaatta taatgtttta ggtctgtgta
    64681 gataaaatcc acatattgaa ttaaatcaat aaatttttca tgatcaacaa aggcagtagt
    64741 ttcaatggca gtgtgtatgt gatgttcttt agctgatttt aagatggctt tagcaaattc
    64801 aaactgagca aatatttcac ctcctgataa agttaaacct ccaccggatt cttcgtaaaa
    64861 ttctttgtct tttaatacct ctgtaataat ttcttctaca gtcttttctt caccgactaa
    64921 ggtgaatttc tctcgttgag catctttcat tttttcaggt ttcattcttt gagattcagg
    64981 attagaacac catggacagc gcagaggaca tccttttaaa aaaacagttg tacgaatacc
    65041 cgggccgtca tgaattgaaa agtgttgaat attaaaaata attcctttag atatttccat
    65101 aagagttcct cctcttcata agtctatcct atcacaaaaa cgaaagaaaa acaattacga
    65161 acgaaagttt aatttgttgt tttttgcttt ttattttggt agaataaaac ggaggtgtaa
    65221 aatgaaaaga ttggaacaaa ttattaaatt agtatcagaa tatgaaaaga tcgacgttaa
    65281 tacattatcg gaaaaattaa atgtatcgaa agtaacgatt agaaaagatt tagataaatt
    65341 agagtcaaaa ggtttattac acagagagca tggatatgct gtattaaata gtggagatga
    65401 cttaaatgta cgtttgtcaa ttaactatga aattaagaga aaaattgttc aggaagcagt
    65461 aaaattggtg tcagataatg aaacaataat gatagaatct ggatcgacct gtgctttact
    65521 tgctgaggaa atttgcaagc aaaaaagaaa tgttacgatt gtaacaaatt cattttttat
    65581 agcaaatttt gtgagagctt atgattcatg tcgtattatt gttcttggtg gagagtttca
    65641 gaaggattca caggttactg tgggaccttt attaaaagaa atgatacaga cttttcatgt
    65701 gcatcaagct tttgttggga cagatggtta cgataaagag atgggcttta caggaaaaga
    65761 tttaatgcgc agtgaggtag ttcaatatat ttcagcagcg tcggataaag tcattgtact
    65821 aactgactca agtaaatttg ataaaagggg tacagtaaga agatttgctt taagtcaagt
    65881 ctatgaagta ataacagacg aaaaactttc taaacaaaat atagctacat tagaaaatgc
    65941 tgggataatg gttaaggtag tttcgtaaga ggttaaatgt atgaatcaag ataggaataa
    66001 actgctctct aaaattgctt atctgtatta tattgaaaac ttaaatcagt cacaaatagc
    66061 agcaaaatta ggaatttata gaacctctat tagtagaatg ttaacagaag caaggaatgc
    66121 aggaattgtt aaaattgaaa tagagaattt tgataccaat atgtttaagt tggaaaatta
    66181 tgtaaaagaa aaatatggtc tggaaagttt agaaattatt ccaaatgaat ttgatgataa
    66241 tccaacaatt ttatctgaaa gaatttctca agttgcagca ggtgtcctta ggaatctaat
    66301 tgatgataat atgaaaattg gcttttcttg ggggaaaagt ttaagtaatt tagtagattt
    66361 aattcacagt aaaagtgtcc gaaatgttca cttctatcct ctagcaggtg gtcctagtca
    66421 catacacgct aaataccatg tgaatacact gatttatgaa atgtctagaa aatttcatgg
    66481 agagtgtaca tttatgaatg caacgattgt gcaagaaaat aaattgttag cagatggtat
    66541 tttgcaatca agatattttg aaaatttgaa aaatagttgg aaagatttag atatagctgt
    66601 agtcggaatt ggtgatttta gcaataaagg aaagcatcaa tggttagaca tgcttacaga
    66661 ggatgacttt aaagaattga ccaaagttaa aactgtagga gaaatttgtt gtcgattttt
    66721 tgattcaaaa ggtaaagaag tctatgaaaa cttacaggaa agaacgatag caatctcttt
    66781 ggaagattta aaaaatattc ctcaaagttt agctgttgct tacggtgata cgaaagtatc
    66841 ttcgattctt tctgtcttgc gtgctaattt agtaaatcat ttgattacag acaaaaatac
    66901 aattttaaaa gttttggaag aagatgggga tttgactttt agagagattc taggtgagtg
    66961 aaaatgatag actgatcagt ttatcgtttt ttctttttag tcgattgcac atttgtgctc
    67021 atataaacaa aaatagttta tctgttgttt ttggattgac aactttatta tgtagttgta
    67081 ttctatagtt acaaaagaaa attttaaaat ttcaaatgaa aaaagctttt tacatagtga
    67141 aatgaggagg aatttatgga aattattgtt ccagatcaaa ttatcatggg tttaatttta
    67201 tatgctggtg atgcgaaaca acatatttat aaagcgttag attacataaa aaatggtaca
    67261 tgtgaacggt gtgaagaaga aatccagtta gctgatgccg ccttattaga agcccataat
    67321 ctacaaacaa aattcttggc acaagaagcg tctggtacaa agacagaaat tacagctctc
    67381 tttgttcatt cacaagatca tctcatgact agtatgacgg agattaattt aatcaaagaa
    67441 attattagtt tgagaaaaga acttcataaa aaataatact agagtattat cattgttatt
    67501 aacatagagg aggaaaacat aatggtgaag attggtttgt tttgtgcagc aggtttttct
    67561 actggtatgc ttgtaaataa tatgaaaatt gcagcgcaag ctagtggagt tgaggcagaa
    67621 atagaggcgt tttctcagtc taaattagcg gattatgcgc caaatataga tgttgcacta
    67681 ttgggtccac aagttgctta tacattagat aaatcaaaag aaatttgtga taagtgtgat
    67741 gttccgatag ctgttattcc gatgatggac tatggtatgt tagatggaaa aaaagtatta
    67801 gatttggccc tatctttgat tagtgggtaa gaaaaggaga tttattatgg caaagatgga
    67861 tgttcagaaa atcattgcac cgatgatgaa gtttgtgaat atgcgtggca ttatagctct
    67921 aaaagatggg atgttagcaa ttttgccatt gacagtagtt ggtagtttat tcttgattat
    67981 gggacaattg ccgttcgaag gattaaataa gagcattgct agtgtttttg gagctaattg
    68041 gacagagccg tttatgcaag tatattcagg aacttttgct attatgggtc taatttcttg
    68101 tttttcaatt gcctattctt atgctaagaa tagcggagta gaggctttac cagctggagt
    68161 tctatctgta tctgcattct ttattttgct aagatcatct tatatcccta aacaaggtga
    68221 ggcaattggg gatgctatta gtaaagtttg gtttggaggt caaggaatta tcggtgctat
    68281 cattataggt ttggtagtag gaagtattta taccttcttt ataaagagaa aaattgttat
    68341 taagatgcca gaacaagttc cacaagctat tgccaaacag tttgaagcaa tgattccagc
    68401 atttgtaatt ttcttacttt ctatgattgt atatatttta gcgaagtcat tgactaatgg
    68461 cggaacattc atagaaatga tttattctgc tattcaagtt ccattgcaag gtttaactgg
    68521 atcttggtat ggtgcaattg gaattgcatt ctttatatca tttttgtggt ggtttggtgt
    68581 tcatggacaa tcggtagtaa atggagtagt gacagctctg cttttatcta atcttgatgc
    68641 taataaagct atgttagcct ctggtaatct atcattagaa aatggtgcac atattgttac
    68701 tcaacaattt ttagattcat ttttaattct atcaggttca gggattacgt ttggtcttgt
    68761 agttgccatg ctttttgcag caaaatcaaa acaataccaa gccttaggaa aagttgccgc
    68821 ttttccagca atatttaacg taaatgagcc agttgtattt ggatttccga ttgtcatgaa
    68881 tccagttatg tttgtacctt tcattcttgt tcctgtactt gcagctgtga tagtatatgg
    68941 agctattgca acaggtttca tgcagccatt ctcaggggta acattgcctt ggagtacacc
    69001 agctatttta tcaggatttt tggtgggtgg atggcaagga gttattactc agctggtgat
    69061 attagcgatg tctacattgg tttattttcc attctttaaa gtacaggatc gtttagctta
    69121 ccaaaatgaa atcaaacaat cttagaggta tttgtgtgtt actgttaaac tcacacattt
    69181 gtgctaaaaa ttagagagtt aaaatttttc tagttaaaag cttgaaaatt tctataaaaa
    69241 tcggtattat attttcgaaa gaaataaaaa tattttcgaa agaaaggtgg ttacgatggt
    69301 aaatacagaa gtagcaagaa caacaatcaa gacagaatat tttggcagcc ttactgaaag
    69361 gatgaacaaa tatcgagaag atgttttaaa taaaaaacct tatattgatg ctgagagagc
    69421 agttctagca acacgcgcct atgaacgata caaggaacaa cctaatgtcc taaaacgtgc
    69481 atatatgctg aaagaaattt tggaaaatat gactatctat attgaagaag aatctatgat
    69541 tgggggaaat caagcttctt ccaataaaga tgctcctatt tttccggaat atacgctaga
    69601 atttgttctc aatgagttgg atctttttga aaagcgtgat ggagatgttt tctatattac
    69661 agaagaaaca aaagaacaac ttagaagtat tgctccgttt tgggaaaata ataatttacg
    69721 tgctagagct ggtgccttat tacctgaaga agtgtctgtt tatatggaaa caggattctt
    69781 cggtatggaa ggtaagatga attctggaga tgctcaccta gcagttaact atcagaaact
    69841 tttgcaattt ggcttaagag gttttgaaga gcgggctcgt aaagcaaaag cagctctaga
    69901 tttaacagat ccagcaagta ttgataaata tcatttttac gactctatat ttatcgtaat
    69961 cgatgctatt aaagtatatg caaagcgctt tgttgctctt gctaaaagtt tagccgaaaa
    70021 tgcaaatcct aaacgtaaga aagaattact tgagattgca gatatttgct ctagagtccc
    70081 atatgaaccg gcaactactt ttgcagaagc tattcaatca gtttggttta ttcaatgtat
    70141 tttacaaatt gaatctaatg gccactctct ttcatatggc cgttttgatc aatatatgta
    70201 tccatatatg aaggctgatt tagaaagtgg taaagaaaca gaagatagca ttgttgaacg
    70261 tctgacaaat ctttggatta agacaattac aattaataag gttcgcagtc aatcacatac
    70321 attttcttca gcaggaagtc ctttatatca aaatgttaca attggtggac agactcgaga
    70381 taagaaggat gctgttaacc cattatctta tttggtatta aaatcagttg cacaaaccca
    70441 tctaccgcaa cctaatctaa ctgtacgtta ccatgcaggt ttagatgctc gtttcatgaa
    70501 tgagtgtatt gaagtgatga aacttggttt tggtatgcct gcatttaata atgatgagat
    70561 tattattcct tcttttattg caaaaggagt attggaagat gatgcttatg attacagtgc
    70621 cattggatgt gttgaaacgg cagttccagg gaaatggggc tatcgttgca caggtatgag
    70681 ttatatgaac ttccctaagg ttctacttat cacgatgaat gatggaattg atccggcttc
    70741 gggtaaacgg tttgcaccaa gctttggtca ttttaaggat atgaagaact tttctgaatt
    70801 agaaaatgct tgggataaaa cactaagata tttgacacga atgagtgtta ttgttgaaaa
    70861 ttctattgat ttatcattgg aacgagaagt tcctgatatt ctatgttcag cattgactga
    70921 tgattgtatt ggtcgtggaa aacaccttaa agaaggtgga gcagtatatg attatatatc
    70981 aggattgcaa gttggaattg caaatttgtc ggattcatta gctgcaatta aaaaattggt
    71041 gtttgaggaa gaacgtataa gcccaagtca gctttggcat gcattggaaa cagattatgc
    71101 cggagaagaa ggtaaggtca ttcaagaaat gttgattcat gatgcaccta agtatggtaa
    71161 tgatgatgat tatgctgaca aattggttac tgctgcttat gacatttatg ttgatgaaat
    71221 tgctaaatat cctaatacac gttatggaag agggcctatt ggaggaattc gttattcagg
    71281 aacatcttct atatcagcca acgtagggca gggacgtgga acattagcaa ctccagatgg
    71341 acgcaacgcg ggtacaccgt tagcagaggg ttgttcacca tcacataata tggatcaaca
    71401 cggccctaca tctgttttaa aatctgtttc aaaattacca acagatgaaa tcgtaggtgg
    71461 ggttctctta aatcagaaag taaatcctca aacgttagcc aaagaagaag ataaattaaa
    71521 actaattgct ttgttacgaa cattctttaa tcgtttacat gggtaccata ttcaatacaa
    71581 tgttgtttcc agagagacgt tgattgacgc tcagaaacat cctgaaaaac acagagactt
    71641 aattgttcgt gttgcaggat actctgcatt cttcaatgtt ctttctaagg caacccaaga
    71701 tgacattata ggacgtactg agcatacttt gtaaaataaa gaggttcttt ttatggaatt
    71761 tatgcttgac acattaaatt tagatgagat taaaaagtgg tctgaaattt tgccgctagc
    71821 tggggtaact tcaaatccca ctattgcaaa aagagagggt tctattaatt tttttgaacg
    71881 aatcaaagat gtaagagaat tgattggctc cacaccctct attcatgttc aggtgatttc
    71941 tcaagatttt gaaggcatct taaaggatgc tcatgaaatt cgaagacaag caggagatga
    72001 tatatttatc aaagtacctg ttactccagc tggattacgt gcaataaagg tgctaaaaaa
    72061 agagggctac catatcactg caacagctat ttatacagtt attcagggat tattagctat
    72121 cgaagcagga gcggattacc tagctccata ttataataga atggaaaatc tgaacattga
    72181 ttcaaattct gtcattcgtc aattagttct tgctattgat agacagaact ctcctagtaa
    72241 gattttggct gcatccttta aaaatgtagc acaagtaaat aatgctttag ctgcaggtgc
    72301 gcatgctgtt acagcaggag cagatgtttt tgaatcagct ttcgccatgc catctatcca
    72361 aaaggcggtt gatgattttt ctgacgattg gtttgttact caaaatagtc gttccattta
    72421 gatagagagg aaatacatat gagaattttt gctagtcctt ctagatatat tcagggggaa
    72481 aatgccttgt ttgaaaatgc caaatcaatt ttggatttgg gaaattaccc tattctatta
    72541 tgcgatcagt tggtttatga tattgttgga aaacgatttg aagattatct acataggtat
    72601 ggtttccata ttgttctggc gctatttaat ggtgaagctt ctgacaatga aatcaatcga
    72661 gttgttgcct tggctgagaa agaaaattgt gatagtatta tcggtcttgg tgggggaaag
    72721 acgattgata gcgcaaaagc tattgcagat ttgattgaaa agcctgttat tattgctcca
    72781 acaattgcat cgaccgacgc acctgtatct gctttatctg ttatttatac agatgaaggt
    72841 gcatttgatc attatctatt ttattctaaa aatccagatt tagttttggt tgatacaaaa
    72901 gttatttcac aagcccctaa gcgtttatta gcgtctggta ttgcagatgg tttagcaact
    72961 tgggttgagg cgcgtgcggt tatgcaggca aatggaaaaa ctatgttggg acaacagcaa
    73021 acattggctg gagttgcaat tgcgaagaaa tgtgaagaaa cgctgtttgc agatggttta
    73081 caggctatgg cagcttgtga agctaaagtg gtgacaccag cattagaaaa tattgttgaa
    73141 gctaatactt tattgagtgg tctaggtttt gaaagtggag gattagctgc ggcgcatgca
    73201 attcataatg gttttactgc attgacaggt gacattcatc atttaacaca tggtgaaaaa
    73261 gtagcttatg gaactttagt acaactatta ttggaaaata gacctaaaga agaacttgat
    73321 aagtatattg agttttacaa aaaaattggt atgccaacaa ctctaaaaga aatgcatttg
    73381 gatcaagttg gatatgatga tttaataaaa gttggtaaac aagcaactat ggagggtgag
    73441 acaattcatc agatgccgtt taagatttcg ccttcagatg ttgctcaagc tattatcgct
    73501 gtagatgcct atgtaaattc aaaataaaca ataaggacta ctgttttcca aatggtagtc
    73561 ttttattgat ccccgtattg aattctatag aagattgaaa taggatgaga acaaatcgat
    73621 tgggaaagta aaattaattt ctataaatgt tttagcaatt gtttcgtact atttcagatt
    73681 cagtctacta tacgttcttc ataaatcaaa aagcgacata ggttgtcggc tatttattgt
    73741 gaatacatta attagcattc cagttttatc ttcggtctaa aataagtatt ttgtgctata
    73801 cgagataagc gtcttgactt actccttgat ttactgcata acaatgggat aaaaagtggg
    73861 agatagagca attcatagtc atcaaaatta atgagataca gtatacagtt tttcctttaa
    73921 acacatttca aattccctca aaaatggtat aatagtaaca tcacaaaatt ggagagagac
    73981 catgagtttt tacaatcata aagaaattga gcctaagtgg cagggctact gggcagaaca
    74041 tcatacattt aagacaggaa cagatgcatc aaaacctaag ttttatgcgc ttgatatgtt
    74101 cccttatccg tctggagctg gtctgcacgt aggacaccca gaaggttata ctgcaaccga
    74161 tatcctcagt cgttacaaac gtgcgcaagg ctacaatgtc cttcacccaa tgggttggga
    74221 tgcttttggt ttgcctgcag agcaatacgc tatggatact ggtaatgacc cagcagaatt
    74281 tacagcggaa aacattgcca acttcaaacg tcaaatcaat gcgcttggat tttcttatga
    74341 ctgggatcgt gaagtcaata caacagatcc aaactactac aagtggactc aatggatttt
    74401 caccaagctt tacgaaaaag gcttggccta tgaagctgaa gtgccagtaa actgggttga
    74461 ggaattggga actgccattg ccaatgaaga agtgcttcct gacggaactt ctgagcgtgg
    74521 aggctatcca gttgtccgca aaccaatgcg ccaatggatg ctcaaaatca cggcttacgc
    74581 agagcgcttg ctcaatgact tagatgaact agattggtca gagtctatca aggatatgca
    74641 acgcaactgg attggtaaat caactggtgc caatgtaact ttcaaagtaa aaggaacaga
    74701 caaggaattt acagtcttta ctactcgtcc ggacacactt ttcggtgcga ctttcactgt
    74761 cttggctcct gaacatgaat tagtagacgc tatcacaagt tcagagcaag cagaagctgt
    74821 agcagactat aaacaccaag ccagccttaa gtctgacttg gttcgtacag accttgctaa
    74881 ggaaaaaact ggtgtttgga caggtgccta tgccatcaac cctgtcaatg gtaaggaaat
    74941 gccaatctgg attgcggact atgttcttgc tagttatgga acaggtgcgg ttatggctgt
    75001 gcctgcccac gaccaacgtg actgggaatt tgccaaacaa tttgaccttc caatcgtcga
    75061 agtacttgaa ggtggaaatg tcgaagaagc tgcctacaca gaggatggcc tgcatgtcaa
    75121 ttcagacttc ctagatggat tgaacaaaga agacgctatt gccaagattg tggcttgctt
    75181 ggaagaaaaa ggctgtggtc aggagaaggt tacctaccgc ctccgcgact ggctctttag
    75241 ccgtcaacgt tactggggtg agccaattcc aatcattcat tgggaagatg gaacttcaac
    75301 agctgttcct gaaactgaat tgccgcttgt cttgcctgta accaaggata tccgtccttc
    75361 aggtactggt gaaagtccac tagctaactt gacagattgg cttgaagtga ctcgtgaaga
    75421 tggtgtcaaa ggtcgtcgtg aaactaacac catgccacaa tgggctggtt caagctggta
    75481 ctacctccgc tatattgacc cgcacaatac tgagaaattg gctgatgagg acctcctcaa
    75541 acaatggttg ccagtagata tctacgtggg tggtgcggaa catgctgtac ttcacttgct
    75601 ttatgctcgt ttctggcata aattcctcta tgacctcggt gttgttccga ctaaggaacc
    75661 attccaaaaa ctctttaacc aagggatgat tttgggaaca agctaccgtg accaccgtgg
    75721 tgctcttgtg gcaaccgaca aggttgaaaa acgtgatggt tccttctttc atatagaaac
    75781 aggggaagag ttggagcaag cgccagccaa gatgtctaaa tcgctcaaga acgttgttaa
    75841 cccagatgat gtggtggaac aatacggtgc cgataccctt cgtgtttatg aaatgtttat
    75901 gggaccactc gatgcttcga ttgcttggtc agaagaaggt ttggaaggaa gccgtaagtt
    75961 ccttgaccga gtttaccgtt tgattacaag taaagaaatc cttgcggaaa acaatggtgc
    76021 tcttgacaag gcttacaacg aaacagtcaa agctgttact gagcaaattg agtctctcaa
    76081 attcaacaca gctattgccc aacttatggt ctttgtcaat gctgctaaca aggaagataa
    76141 gctttatgtt gactatgcca aaggctttat tcaattgatt gcaccatttg cacctcactt
    76201 ggcagaagaa ctctggcaaa cagtcgcaga aacaggtgag tcaatctctt atgtagcttg
    76261 gccaacttgg gacgaaagta aactggttga agacgaaatc gaaatcgttg tccaaatcaa
    76321 aggtaaagtc cgtgccaaac tcatggtcgc taaagaccta tcacgtgaag aattgcaaga
    76381 aattgctcta gcggatgaaa aagtcaaagc agaaattgac ggtaaggaaa tcgtgaaagt
    76441 gattagtgta ccaaataaat tggttaatat tgttgtaaaa taaccaattt atttgctgat
    76501 ttccaacctc aaacagtttc ccaaactgtt tgagccaact aaactcgtta atatcgttgt
    76561 gaaataaggt aggaatcctt cagagtagaa tctggaggat tttttgaatc ttcttatgaa
    76621 agtatggtat actatgggca actataaagt ttgaaaagtg aaaaaaggag aaagctatgc
    76681 cagtaaatga atatggtcaa atgattgggg agtcaatgga aggttataca ccaggtgaac
    76741 tgccttctat tgatttctta gaagggcgtt atgctaggat agaggctctt tcagtggaaa
    76801 agcatgcgga ggatttgcta gctgtttatg gcccggatac tcctcgggag atgtggacct
    76861 acctttttca ggagccagta gcagatatgg gggagctggt tagcctttta catcagatgt
    76921 tggctcgtaa ggaccgtttt tactatgcaa tcatagacaa ggcgactggt aaggctttgg
    76981 gatctttttc tctcatgcgc attgaccaga ataaccgagt aatagaagtc ggagcagtca
    77041 ctttttctcc agagctaagg ggtacacgga taggaactga agctcagtat ctcctagctc
    77101 gctatgtttt tgaggagcta aactatcgtc gctacgagtg gaaatgcgat gccttaaatc
    77161 tgccatccag acgagctgcg gagcgtttga gctttattta tgaaggaacc ttccgtcagg
    77221 cagtggttta taagggacgt acgagagata cggattggtt gtctatgatt gataaggact
    77281 ggcctcaagt caaagatcgt ttggaaacat ggttgcgtcc tgaaaatttt gataaaaatg
    77341 gacagcagta caagagcttg agagaacttt aagaggtgtt gagatgatta ctattaaaaa
    77401 gcaagaaatt gtcaagctag aggatgtttt acatctctat caggctgtcg gttggacaaa
    77461 ttatacccat caaccagaga tgctggagca ggccttatct cattcattag taatttatct
    77521 ggcacttgat ggtgatgctg tggtgggctt gattcgtttg gttggagatg gattctcatc
    77581 agtattggtt caggatttaa tcgttttacc aatctatcag cgtcaaggaa ttggtagtgc
    77641 cttgatgaaa gaggctttag aggattacaa agatgcctat caagtccagc tggtgacaga
    77701 agagacagaa agaaccttgg gcttctatcg ttctatgggc tttgaaatct tatccaccta
    77761 taattgtata gggatgactt ggatgaatcg taaaaaataa caaaacttgt tttttcttaa
    77821 gcaaaattta aggatggtct agtattatat agtcattaaa taaagacctc ctaactttat
    77881 ttaataaaat cctaaacttt tttcatcaca atctcctaat gaagccaccc aatcaggtgg
    77941 cttttttgcg tggtgaggtg ctggtgatag aaattttttg caaaatagta aaattttaga
    78001 aaagttaagc tagttttaag tttcgtcttg tatcatgtag ttattaaata aagacctcct
    78061 aactttattt aataaaatcc taaacttttc tttttcataa taatctccct taacttcacc
    78121 caatcaggtg gagtttttta gctctatttc aggcttttgg ggactattct aaaaataatt
    78181 tttcgatatt tttcggtatt tttcggattt tggtcgggga attggcgggg acttttttag
    78241 cgaatataac taagaaatag gtctgtggtc gcttcagcta gttcaaactc aatttgattg
    78301 taagtgactg ttaattgaag aactggaact actgtaataa tgattttgct tgtctagtag
    78361 tggcgtatta aatgagaagt aacatgtaag attgtctctt cgtttacgaa atcaaaattt
    78421 ctatgaaatt gatagaatcc ctaacgttct cttaatctta accgtcttgt cgtacagcgg
    78481 ttgaagaaaa tgtaaacctt tgacaaaatt cgtgaactat gggataataa aaaggaattg
    78541 agtactagtt ctatatcata ggctagaaaa gaccccaagc tcacgaccaa ataagcttga
    78601 ggtctttttt gacactattt gtccttgttt agccatttat cgactatacg aagaacgaca
    78661 ccgaccacaa ttggtccgat gatagttttg agtactaatt ccatcatggg ctatctcacc
    78721 tcctttcgta ggcggtgtag cagtgtcgta gaatattata ccacataagt gctaaactta
    78781 ggagtcaccc aatcaggtgg cttttttgtt tgtggcttgg ttttttgata taatagagcc
    78841 atgagtagaa ttttagataa tgagataatg ggggatgagg agttagtaga acgcacgctc
    78901 cgtcctcagt atttacgtga atatatcgga caggataagg tcaaggacca gctacaaatc
    78961 tttattgaag ctgccaaaat gcgggatgaa gcgctggatc atgtgctctt atttgggcct
    79021 ccaggtctcg ggaaaacgac catggccttt gttattgcca acgaactggg agtcaatctt
    79081 aagcagacgt cgggtccagt cattgaaaaa gccggagatc tggtagctat tttgaatgag
    79141 ttagagcctg gggatgtact ttttattgat gagatccatc gtttgccaat gtcagtggaa
    79201 gaggtgcttt atagtgctat ggaggacttc tacatcgata ttatgattgg ggctggtgag
    79261 ggtagtcgta gtgttcattt ggagttacca ccttttacct tgattggtgc gacgactcgg
    79321 gctggtatgc tctccaatcc gctacgggca cgttttggga ttacaggcca tatggagtat
    79381 tatgcccatg ctggcttgac agaaattgtc gagcggacgg cagatatttt tgagatggaa
    79441 atcactcatg aggcagcatc tgagttggcc ctacgtagtc gtgggacccc tcgtattgcc
    79501 aatcgtctcc tcaagcgcgt gcgcgatttt gcccagataa tggggaatgg ggtaattgat
    79561 gatattatta ccgataaggc tttgactatg ctggatgttg accatgaagg tttggactat
    79621 gtggatcaaa aaatccttcg taccatgatt gagatgtaca gtggaggacc tgttggtcta
    79681 ggaactcttt ctgtgaatat cgccgaagag cgtgagacag ttgaagatat gtatgagcct
    79741 tacttgattc aaaaaggttt tatcatgcgg acacggtctg gacgggtggc gactgctaag
    79801 gcatatgagc acttaggtta tgaatacagt gaaaaataag caagaaatct tagaggcttt
    79861 tagagaaaat ccagatatga tggccattct gacgatcatc cgagaccttg gtctgaaaga
    79921 ctcgtggttg gcagcaggtt ctgtcagaaa tttcatttgg aatcttttgt cagacaaatc
    79981 cccttttgat catgaaacag atatagatgt gattttcttt gatccagatt tttcttatga
    80041 ggaaacctta ttactggaga aaaagctgcg agaggatttt cctcagtacc agtgggaatt
    80101 gaaaaatcag gtctatatgc atcagcacag tcctcacact gcttcctata ccagttctcg
    80161 tgatgctatg agtaagtatc cagaacggtg tacgacagtt ggactgcgct tgaatgaaga
    80221 atcagatttt gaactctatg caccttatgg tttggaggat attttgaatt ttcaagttcg
    80281 tccaactcct catttcttag aaaatgaaga ccgaatggaa ctctatcaaa cacgtttatc
    80341 caagaaaaat tggcaggaga aatggaaaaa tttgattttt aaaaatactt aaggaaactt
    80401 taagctaggg agtgtacact aagttcataa gttaagaaga ccttaactta aactcctaaa
    80461 actttttcat aataatctcc ctataaaaat aaagtcgcct aatcaggcgg cttatttttt
    80521 tgaaaaatgg gcttggtgcc tgagaataaa tagcttagtg atagaagaaa atggggaaat
    80581 atggtataat gaaacgatag atttttgaat aggaataaga tcatgtttgg attttttaag
    80641 aaagataagg ctgtggaagt agaggttccg acacaggttc ctgctcatat cggcatcatc
    80701 atggatggca atggccgttg ggctaaaaaa cgtatgcaac cgcgagtttt tggacacaag
    80761 gcgggcatgg aagcattgca aaccgtgacc aaggcagcca acaaactggg cgtcaaggtt
    80821 attacggtct atgctttttc tacggaaaac tggacccgtc cagatcagga agtcaagttt
    80881 atcatgaact tgccagtaga gttttatgat aattatgtcc cggaactaca tgcgaataat
    80941 gttaagattc aaatgattgg ggagacagac cgcctgccta agcaaacctt tgaagcttta
    81001 accaaggctg aggaattgac taagaacaac acaggattga ttcttaattt tgctcttaac
    81061 tatggtggac gtgctgagat tacacaggcg cttaagttga tttcccagga tgttttagat
    81121 gccaaaatca acccaggtga catcacagag gaattgattg gtaactatct ctttactcag
    81181 catttgccta aggacttacg agacccagac ttgattatcc gtactagtgg agaattacgt
    81241 ttgagcaatt tccttccatg gcagggagcc tatagtgagc tttattttac ggacacctta
    81301 tggcctgatt ttgacgaagc agccttgcag gaagctattc ttgcctataa tcgtcgccat
    81361 cgccgatttg gaggagttta ggaggaaata tgacccagga tttacagaaa agaaccttgt
    81421 ttgcagggat tgccctggct attttcctac caattttaat gattgggggc ctcttgcttc
    81481 agatagcaat cggaatcata gccatgctag ccatgcatga acttttgaag ataagaggtc
    81541 tagcgaccat gacgatggag ggcctcttga ctctctttgc aacctttgca ttaaccattc
    81601 ccttggagaa ttacctgact tttttgccag ttgatgggaa tgtggttgcc tatagtgttt
    81661 tgatttcaat catgttagga acgaccgttt ttagcaagtc ttatacgatt gaggatgcgg
    81721 ttttccctct tgctatgagc ttctacgtgg gctttggatt taatgcttta ctagatgctc
    81781 gtgttgcagg tttggacaag gctctcttag ccttgtgtat cgtctgggcg acagacagtg
    81841 gtgcctatct tgttgggatg aactatggga aacgaaagtt agcaccaagg gtatcgccta
    81901 ataaaaccct tgagggtgcc ttgggtggta ttttaggagc aattttagta accattatct
    81961 ttatgatagt tgacagtaca gttgctcttc catatggaat ttacaagatg tcagtctttg
    82021 ctattttctt tagcattgct ggacaatttg gtgatttact agaaagttcg atcaaacgtc
    82081 attttggtgt taaggattct gggaaattta tccctggaca tggtggtgtt ttggatcgtt
    82141 tcgatagtat gttgcttgta tttccaatca tgcacttatt tggactcttt taatcaaaag
    82201 acggaggaaa cgctatgctc ggaattttaa cctttattct ggttttcggg attattgtag
    82261 tggtgcacga gttcgggcac ttctactttg ccaagaaatc agggatttta gtacgtgaat
    82321 ttgccatcgg tatgggacct aaaatttttg ctcacattgg caaggatgga acggcctata
    82381 ccattcgaat cttgcctctg ggtggctatg tccgcatggc cggttggggt gatgatacaa
    82441 ctgaaatcaa gacaggaacg cctgttagtt tgacacttgc tgatgatggt aaggttaaac
    82501 gcatcaatct ctcaggtaaa aaattggatc aaacagccct ccctatgcag gtgacccagt
    82561 ttgattttga agacaagctc tttatcaaag gattggttct ggaagaagaa aaaacatttg
    82621 cagtggatca cgatgcaacg gttgtggaag cagatggtac tgaggttcgg attgcacctt
    82681 tagatgttca atatcaaaat gcgactatct ggggcaaact gattaccaat tttgcaggtc
    82741 ctatgaacaa ttttatctta ggtgtcgttg ttttttgggt tttaatcttt atgcagggtg
    82801 gtgtcagaga tgttgatacc aatcagttcc atatcatgcc ccaaggtgcc ttggccaagg
    82861 taggagtacc agaaacggca caaattacca agattggctc acatgaggtt agcaactggg
    82921 aaagcttgat ccaagctgtg gaaacagaaa ccaaagataa gacggcaccg actttggatg
    82981 tgactatttc tgaaaagggg agtgacaaac aagtcactgt tacacccgaa gatagtcaag
    83041 gtcgttacct tctaggtgtt caaccggggg ttaagtcaga ttttctatcc atgtttgtag
    83101 gtggttttac aactgctgct gactcagctc tccgaattct ctcagctctg aaaaatctga
    83161 ttttccaacc ggatttgaac aagttgggtg gacctgttgc tatctttaag gcaagtagtg
    83221 atgctgctaa aaatggaatt gagaatatct tgtacttctt ggcaatgatt tccatcaata
    83281 ttgggatttt taatcttatt ccgattccag ccttggatgg tggtaagatt gtgctcaata
    83341 tcctagaagc catccgccac aaaccattga aacaagaaat tgaaacctat gtcaccttgg
    83401 ccggagtggt catcatggtt gtcttgatga ttgctgtgac ttggaatgac attatgcgac
    83461 tcttttttag ataatcgagg aatattatga aacaaagtaa aatgcctatc ccaacgcttc
    83521 gcgaaatgcc aagcgatgct caagttatca gccatgctct tatgttgcgt gctggttatg
    83581 ttcgccaagt ttcagcaggt gtttattctt atctaccact tgccaaccgt gtgattgaaa
    83641 aagctaaaaa catcatgcgc caagaattcg aaaagattgg tgctgttgag atgttggctc
    83701 caacccttct tagtgcagaa ttgtggcgtg aatcaggtcg ttacgaaacc tatggtgaag
    83761 acctttacaa actaaaaaac cgtgaaaaat cagactttat cttaggtcca actcacgaag
    83821 aaacctttac agctattgtc cgtgattctg ttaaatctta caagcaattg ccactcaacc
    83881 tttatcaaat tcagcccaag tatcgtgatg aaaaacgccc acgtaatgga cttcttcgta
    83941 cacgtgagtt tatcatgaag gatgcttata gtttccacgc taactatgat agtttggata
    84001 gtgtttatga tgagtacaaa gcagcctatg agcgtatttt cactcgtagt ggtttagact
    84061 tcaaggctat tattggtgac ggtggagcca tgggtggtaa ggatagccaa gaatttatgg
    84121 ccattacatc tgctcgtaca gaccttgacc gctgggttgt cttggacaag tcagttgcct
    84181 catttgacga aattcctgca gaagtgcaag aagaaatcaa ggcagaattg ctcaaatgga
    84241 tagtctctgg tgaagatacc attgcttact caagtgagtc tagctatgca gctaacttag
    84301 aaatggcaac aaacgagtac aaaccaagca accgtgttgt cgctgaagaa gaagttactc
    84361 gtgttgcaac gccagatgtt aaatcaattg atgaagttgc agccttcctc aatgttccag
    84421 aagaacaaac gattaaaacc ctcttctaca ttgcagatgg tgagcttgtt gcagcccttc
    84481 tagttggaaa tgaccaactc aacgaagtca agttgaaaaa tcacttggga gcagatttct
    84541 ttgacgttgc tagcgaagaa gaagtggcga atgttgttca agcaggattt ggttcacttg
    84601 gaccagttgg tttgccagag aatattaaaa ttattgcaga tcgtaaggtg caagatgttc
    84661 gcaatgcagt tgtcggtgct aacgaagatg gctaccactt gactggtgtg aacccaggcc
    84721 gtgattttac tgcagaatat gtggatatcc gtgaagttcg tgagggtgaa atttccccag
    84781 atggacaagg tgtccttaac tttgcgcgtg gtattgagat cggtcatatt ttcaaactcg
    84841 gaactcgcta ctcagcaagc atgggagcag atgtcttgga tgaaaatggt cgtgctgtgc
    84901 caatcatcat gggatgttac ggtatcggtg tcagccgtct tctttcagca gtgatggagc
    84961 aacacgctcg cctctttgtt aacaaaacgc caaaaggtga ataccgttac gcttggggaa
    85021 tcaatttccc taaagaattg gcaccatttg atgtgcattt gattactgtc aatgtcaagg
    85081 atgaagaagc gcaagccttg acagaaaaac ttgaagcaag cttgatggga gctggttatg
    85141 aagtcttgac agatgaccgt aacgaacgtg tcggtgttaa atttagcgat agtgacttga
    85201 ttggtcttcc aatccgtatc actgttggta aaaaagcggc cgatggcatt gtagaagtta
    85261 agatcaaggc aactggtgac accattgagg ttcatgcaga taacgtgctt gaaacgcttg
    85321 aaatcctaag caagaaataa aaactataat cagaagaaaa acaaggaaaa aatgtaacta
    85381 gtttttacct tgttttttct gtataatggg agaaatgagt agataaagag gtaaatgtta
    85441 tgctaagatt tccaaaggat tttgtctggg gatcctctac ttctggaccg cagacagaag
    85501 gacgtgtagc tggtgacggt aagggagaca atctctggga ttactggttc caagtggagc
    85561 caaatcgtta ctataatggg attggttcag ataagacatc gactttttat gaaaattggg
    85621 agcgggatat tgagcttttg ttagagactg gtcacacagt ctttcggact tctattcagt
    85681 ggtcacggat ttttccacaa ggctgtggaa aagtcaaccc tcaaggtgtg gatttttatc
    85741 gtaaggtctt tgaggctatt aaggctaaag gaattcgtct gttagtcaat ctctatcatt
    85801 ttgatttacc ttttgctctt caagaggatg gtgatggttg ggaaaataag gcgacagtct
    85861 cagcctatga agactatgct cgtttttgtt ttgagactta tggagattta gtggatcaat
    85921 ggattacctt taacgagccc atcgttcctg tagaatttgg ttatttttat gatgcccatt
    85981 atccacataa ggtggatgca gaggcagctg ttaaggtagc ctatcataca caattggcca
    86041 gcagccgggc tgttaaggct tgccatgaac ttttgcctga ttccaagatt gggattgtcc
    86101 tcaacttgac accggcttat ccacgtagcc agcatcctgc tgatgtcaag gcagctcgta
    86161 ttgcggccct ttttcaggcc caatctttct tagatccatc tgtcttgggg acttatccac
    86221 aggagttggt agaaatcttg catgaacacg gtcttttacc tgatgctaca gaggaagagt
    86281 tggaactcat tcgtgataat acggtggact tccttggtgt gaactactat caacctttgc
    86341 gtgttatggc tcctcgattt gctaagcatc cagatagtcc actcttacca gaacattttt
    86401 acgagcctta tgtgatgcct ggacgtaaaa tcaattctca ccgtggttgg gagatttatg
    86461 agcaagggat ttatgacatc gcccaaaata tcaaggaaaa ttatggcaat attgagtgga
    86521 tgttgactga gaatggtatg ggtgttgaag gggaagaaaa attccgtcaa gatggaatga
    86581 ttcaagatga ttaccgtatt gactttgtaa aaggtcatct tcgtgaactt caccgtgcca
    86641 ttgaagatgg tgccaactgt aagggctact tgatttggac ctttattgac tgctggtcat
    86701 ggctcaacag ctataaaaat cgctatggtt tggtcgaatt agacttggaa acgcaagaac
    86761 gtcgtctgaa gaaatcaggc cactggttca aagaattaag cgataataat ggattttaaa
    86821 aaggactctg actgattatc ccaatcggtc agagtttttt gcttacagga gcttaatttg
    86881 aactatacca atttttactc ttgacaagtg aaagaaacaa gtatatactg tttttgctga
    86941 ttctataaaa gatgaattag actataccaa ttttaaggag aaagcacagc ttgcctgtgt
    87001 cgtatatact atgtgtggaa ttgttggtgt tgttggaaac acaaatgcaa ctgatatttt
    87061 gattcaaggg cttgaaaagc ttgaataccg tggctatgat tctgcgggaa tttttgtcct
    87121 agatggtgct gataaccatt tggtgaaggc tgttggtcgt atcgcagaat tgtctgccaa
    87181 gacagctggt gttgagggaa caactggtat cggacatact cgttgggcaa ctcatgggaa
    87241 accaacggaa gacaatgctc acccacaccg ctctgagaca gaacgttttg tcttggttca
    87301 caatggggtg attgaaaact accttgaaat taaagaagaa taccttgctg ggcaccactt
    87361 caaagggcaa acagatacgg aaatcgccgt acatttgatt ggaaaatttg cggaagaaga
    87421 cggtctctca gttcttgaag cctttaaaaa agctcttcat attatccgtg gttcatatgc
    87481 ctttgccttg attgactctg aaaatccaga tgtcatctat gtagcgaaaa acaaatctcc
    87541 acttttgatt ggtcttgggg aaggctacaa tatggtctgc tcagatgcta tggctatgat
    87601 tcgtgaaacc aaccaataca tggaaattca tgaccaagag ttggtaatcg tcaaggctga
    87661 tagcgtggaa gttcaagact atgatggtaa cagtcgtgaa cgtgctagct atactgcgga
    87721 acttgacttg tcagatatcg gtaagggaac ttatccttac tacatgctta aggaaattga
    87781 tgagcaacca actgttatgc gtaaactcat tcaagcctac acggatgatg ctggtcaagt
    87841 agtgattgat cctgctatca ttaaggctgt tcaagacgca gaccgcatct acatccttgc
    87901 agctggaaca tcttaccatg caggatttgc ttctaagaaa atgttggaag aattgacaga
    87961 tacaccagtt gaacttggca tctcatctga gtggggctac ggtatgccac ttctcagcaa
    88021 gaaaccactc ttcatcttta tcagccaatc tggtgaaaca gcggatagtc gtcaagtttt
    88081 ggtcaaggct aatgaaatgg gaattccaag cttaacagtg acaaacgttc caggttcaac
    88141 cctctcacgt gaagccaact ataccatgct ccttcacgca ggtcctgaaa ttgccgtggc
    88201 atcaactaaa gcctatacag cgcaaatcgc agcccttgcc ttccttgcaa aagcagtcgg
    88261 agaagcaaat ggtaatgcta aagcgcaagc ctttgacctg gttcatgaat tgtcaatcgt
    88321 agctcagtct atcgaatcaa ctctttcaga gaaagaaacc attgaagcca aggttcgtga
    88381 acttcttgaa acaactcgta acgcctttta catcggacgt ggtcaagatt actacgtagc
    88441 catggaagca agtctcaaac tcaaagagat ttcttatatc cagtgtgaag gttttgcggc
    88501 aggagaactc aagcacggaa ccattgcctt gattgaagaa ggaacacctg tcttggctct
    88561 cttgtcagat ccagtccttg ccaaccacac tcgtggaaat atccaagagg tggcagcccg
    88621 tggtgctaag gtcctcacta tcgcagaaga aaatgttgct aaagataccg acgatatcgt
    88681 ccttacgact gtacaccctt acctctcacc aatttcaatg gtcgtaccga cgcaattggt
    88741 tgcttacttt gcaaccctcc accgtggcct cgatgtggat aaaccacgta accttgctaa
    88801 atcagtaacg gtagaataag ctaaaaaagt ctagttatct aggctttttc taatgagcaa
    88861 attggttgct tgtactcaag attcgtgtta gaataatttt tcaaattgaa ggacagagat
    88921 agacaaggag aatcacaatg gtagaattgg gaatttcaac atttggggaa ataacggagc
    88981 ttgaagggac tggacaaact tacagtcatg ctgaacgcat tcgccagttg gtggcagaga
    89041 ttgagctggc tgacaaggtt ggtttggacg tatatgggat tggcgagcac catcgggcgg
    89101 attttgcagt atcagcccca gagattgtcc tggccgctgg ggcagtcaat accaagaaaa
    89161 tccgtttgac cagtgcagtc agcattctgt caagcatgga tccgattcgt ttgttccaac
    89221 agtatgccac tatcgatgct ttgtcaaatg gacgatcgga gattatggct ggaaggggct
    89281 ctttcacgga atctttccct ctgtttggtt atgacttgaa agactacgac tctctttttg
    89341 atgagaaatt agacttgctt cagttagtca atgaaaagac caagttagac tggcaaggtc
    89401 gattgactca aacgattgct ggtaaagaag tttatcctcg cccagttcag gacaaattgc
    89461 ccttgtggat agctacaggt ggtcatgtcg aatcaacagt gaagattgct caggctggtc
    89521 taccgattgt atatgctatt attggtggta atccacgtta ttttaaaaag ttgattcagg
    89581 cttatcgtga gattggaagc gaagcgggcc atgctgacaa agacttgaaa gtgggagccc
    89641 attcttgggg gtggattgcg gaagatggtg agcaggcggt gaaagattat ttccatccga
    89701 ctaagcaagt ggtggatgct atttccaaag accgtccgca ctggcaggaa ttgcgttatg
    89761 agcaatattt ggagcaggta gggccaaatg gcgccatgtt tgttggcaat ccagatcagg
    89821 tggccgaaaa attgattcgc atgatagagg atttaggatt ggaccgcttc atgcttcatc
    89881 taccgcttgg ttctatgcct catgaccagg ttctgagagc tattgaactc ttcggaacac
    89941 aagttgcacc caaagtacga gcttattttg ctatgaaaga ggcttaataa aaaatcctaa
    90001 tcaagtttat taggacaaca aatattgtac aaaaattaat cccccgagct ataatgcttg
    90061 ggggattttt ctataggagg gctagtttag ttctcttttt tattttttag taagaaaccg
    90121 agaccaagga gcgcaaggag gctgattcct gcaaatagga gtttgttttc gtttttgatt
    90181 cctgtatttg gaagttcagc ttgtttatct ggggttgcag gtatattttc cttgctagag
    90241 ttttctaccg attcgtttcg aaccgcttct tttacagatg cttcttgtgc ttcttgtgct
    90301 ggttgttcag cttgtgaatc agctgtagct tggctaggtt tattttccgc atcagctact
    90361 ttggcatctg gtttagtaga atcaggtcta gcttctggag ctgggtcttg atgtgcaggg
    90421 tgagaagctt cattttgatg ttcaggcttg gaaggggttg agtctggttt ctcttctgca
    90481 gttgactcat ggctagttcc attttgagag actcgaagaa cagtagctgt aagggcattc
    90541 aatttcaagc ctttttcagt ccattcaagt cctttcgggt tggcaatttt gactgatcct
    90601 gcttggtttt catctgccaa aacttccgca tttcttagat gtgcaaaggc agttcccaaa
    90661 ttaaattcgc gagctttttc atccgcattg acaaagactg cgtagatatc gccgtttgga
    90721 gcagtgattt ggtagccaat cactacatcc tctttttcca caccattttg gcctgggaca
    90781 gtgatgaggt ggacacggtc tttgatatct tggagactct taagtcggaa ggcatctgta
    90841 gattgacgaa gggcaatcaa acctttcata tagtcacggc tcttgacatt ttcaggataa
    90901 gctttaccat ctgtagcctt agtccagtca aacttgttga ctgcgtcgct agaatcgtaa
    90961 gaatcatgga tgaagtaagg atagtcaaat gggttgccgt ccttatcacg caacaagtga
    91021 gatttgtttg gaaccttatc ctctgctact ggagtcttgt aggctgggtc acggaattgt
    91081 ttagtacgtc catattcctg accggagtgg ataaatggag ttccttgagc tgtcaagacc
    91141 atgagatttc caagtcgtaa acgacggtgg atttcagcat agttctcagc cttgcttggg
    91201 tcttttttga tagactgggc aatgatgtca aagagggtca agttatcatg ggctgctatg
    91261 tattggatga catctccagg gctgtcagct tcaaagttag ttggttgagc aatgagattt
    91321 ttaaagatgg tgttgacatc acgcttgcca cctgtgataa aggcaggttg accttcgttt
    91381 ggataaccag atttgaggtt gttacggatg tcatctgaaa agacagcgac agtatcggta
    91441 tgtttcatcc aatcttggtc agcagcttta gtaggcatgt tttcatcacc ggcataggtt
    91501 ctccaacctt caccaagcat gatgaggttt ggattgaggg cgcgtgcagc cttgtaagct
    91561 tcttcgatag aagcggcgtc atggtctccc atcatatcga aacggaatcc atccactttg
    91621 taggtatcaa ctaggtattt gatagagtca actaggagcc gtttggtcat atggtgggtt
    91681 gttcccaagc gtccaccacc aaagctagtt cgaggtgtgc catcggcatc cataaagtgg
    91741 tagtagtttg gctctaggtc ttcaaagata tcgactttgg ctgtgtggtt ataaacgaca
    91801 tctaggatag ctcccatacc acgtttgtgg atttcgttga tgaggttttt aaattctgcg
    91861 attcgttttt ctggattctt aggatcgctt gagtacatac cagtcaagga gaagtagttt
    91921 tgagggtcat atccccagtt gtagttgctg ttgcttgaag cgtagtcaga caagcgttca
    91981 tggtttttca attcattgac aaagtagtaa gacaagactg gaaggagctg gatatgggtt
    92041 acacccaagt ctttgagata gtctagtttt tcaatgaagg cttcaaaagt cccaaatggt
    92101 ttggtcaagt cttttgcaat ggcaggatct gaagtgaagt cacgcacatg agcttcgtag
    92161 ataacggcgt cttcacgagt cttgaaattg tgaatcttac cataagtcaa gtcttgaggt
    92221 ccgagtttag ctggatctac aaaggcggct ttagccactt tatgggtatc gtcaattttg
    92281 gcatcgtcgc tattccaagc agcaagagat ttagcgtaag gatcgagtgc aagaacagtt
    92341 ttaccttgac gctcgatttg gtattgataa tagtagccag tgaaatctgt gattccgagt
    92401 ttgtttgtgc tgtctagagt ttgtttccaa gttcctcttt cccctttttc gagagcgaca
    92461 gttccaacta ctttgtcagg gtcattcttg tcgtagacaa caacagaaac cttatcagca
    92521 cttggtgacc aaagggtcaa atcaacttgt tttccttctt cttttaggtc agctcccagt
    92581 ttgccatcat agctgtatgt ctcatctttc aggtgccagc ttgttttggt agtgaattgg
    92641 tcggaattgt agctaacagt ataagggtgt tttgtgtcag agaaatctcc gctgtaggtc
    92701 actttcttac cagcttcatc gattgcaaca tcggtaatag ttaccttgtt tcctaggtga
    92761 ttagtgatgt tggagtgttt gaggatatct tcttttttag caccgacaag tgttgaaaag
    92821 ctactttcaa tgctagaagt gcctacgtgt tgggctcctg tcatacggat atcatggaca
    92881 tagtatggat ttgtgtaaat cgattcatca tcgtctttta ggaaaatttg gctatgattt
    92941 ttcaaatctg tgaacttata attttcttta cggattttca cgtcgtctcc ttgtttgctc
    93001 tcatctagta ataaaaatcc aaattctctt gcggcttcat taagaggaat gtcgatatag
    93061 cggccatatt tgcctgtagc cgtaaagtct gttccgtcag gccattgagc gctacttgga
    93121 tttttcacat ctccccagta ccagagagat ttcttgtcat agttgccatc tgtgcggtag
    93181 tagttgacgc gaacagttcc tgcaggctgt ggctcgtaag agaaaacctt gtaatcttgg
    93241 tctaaccaag cttcgttcat ttttggaact agtttttcta cagatttatc gccggttaga
    93301 ttttttccag ctgtattgtt gatgaggaag ctaattttct tggcttgttc tccctttaat
    93361 ttgacatcta ggtaatagcc gtagtcatct ttcttggcat ccttgaagga caaagctccg
    93421 tttggccagt tttcagatgg tttttcaaca tcgtcccaag tccatagtcc ttgagcatcc
    93481 ttgttttctt caggaagttt tttgacatgg atacggaagt agttatcttc gatgggctct
    93541 tctgccttag tttcagttgt tactggacta gtagaagtag ttggctctgt tgcaggtttt
    93601 tcttctgttt tctctaggga agcgtttgca tttctaggtg aagaaatatc actttcgttc
    93661 ttaccagagc cagctgctgt atcagtaaga ggttgggcaa gggtggttgt atttctgttg
    93721 ttgggttcgt tagtggttgg tgtactttcg tcggatgaga tagttggtgt agccatggca
    93781 agcaagacaa ggcttgcgcc gataaggaca gaaccagttc catttttgag ggaacggatg
    93841 ctgtagacca tttttttctc agtgtgagat ggtgtttttc tcataatgat tctccaatca
    93901 ataaatttct atatcagtat agcatgtagt aaaacaatat gcaagcgttt tctttgattt
    93961 gtgaaaaaat tcttactttt gagaagtttt ctgtactatt ttatatatca gtataaatga
    94021 cggagataaa aatgtcacat aagccaagcc gtattattag gaagatgatg tgttcccagc
    94081 tatttttatt cagaaattga tctctaacat taccaataaa aaagaaaaat atcttgacaa
    94141 gcaagggaaa attttgttac aataatagac ggtacttttt acttttggtc tctcaagagt
    94201 gtacagggac gtgctgacaa atgttgcaaa agtacacaca gatgatatct gtcaccaagt
    94261 gtatcatcac caaaaataaa aaaacacagg agaatgtaga tgcctacaat taaccaattg
    94321 gttcgcaaac cgcgtaaatc aaaagtagaa aaatctaaat caccagcttt gaacgttggt
    94381 tacaatagtc ataaaaaagt tcaaacaaac gtttcttcac cacaaaaacg tggtgttgca
    94441 actcgtgttg gaacaatgac acctaaaaaa cctaactcag cccttcgtaa attcgctcgt
    94501 gtacgtttga gcaaccttat cgaagttact gcctacatcc caggtatcgg acacaacttg
    94561 caagagcaca gcgtggtgct tcttcgcggt ggacgtgtaa aagaccttcc aggggtacgt
    94621 taccatatcg tccgtggtgc acttgatact gcaggtgtta acgatcgtaa acaaggccgt
    94681 tctaaatacg gtactaaacg tccaaaagca taaggaaagg ggataaagag aaatgagtcg
    94741 taaaaataga gctccaaaac gtgacgtatt gccagatccg ctatacaatt cacaactagt
    94801 tactcgtctt atcaaccgcg ttatgcttga tggtaaacgt ggtactgctg cttcaatcgt
    94861 ttacggtgct tttgagcaaa tcaaagaagc tactggcaac gatgcacttg aagtatttga
    94921 aacagctatg gaaaacatca tgcctgtact tgaagtacgt gcacgtcgtg ttggtggttc
    94981 taactaccaa gtcccagttg aagttcgtcc agaacgtcgt acaacacttg gacttcgttg
    95041 gttggtaaca atcgctcgtc ttcgtggtga acacacaatg caagaccgtc ttgcaaaaga
    95101 aatcttggat gctgctaaca acactggtgc agcagttaag aaacgtgaag atactcaccg
    95161 tatggctgaa gctaaccgtg cattcgcaca cttccgttgg taagatagga tgcgaaagcg
    95221 ttaagaaagt cccagagaaa atagggaatc gaagcaggtt gcggttgcaa ccaatgagat
    95281 tcatcttttt ctccagactt ttagcttgag ctcaactaaa tcatgatgct aggcacggaa
    95341 ggatgcaagg tgaaaatagg aaactgacgc agtattcaac gaatacaagg agttttatct
    95401 ttttcacgca gcatcccgtt ccagctcaca tcggctaact aactttagcc tgggttcaaa
    95461 ttagctaaat cgattagtat tagctataac tcagcttacc atctcgtaag ttgaaaccaa
    95521 caatagcatg aaaacattga gaacgggtag gtcctgccta tccgttttta ttaaaatcgt
    95581 gttataatag aatagaaatc aaaaataaat aggagaaaca aacctcatgg cacgcgaatt
    95641 ttcacttgaa aaaactcgta atatcggtat catggctcac gtcgatgccg gtaaaacaac
    95701 aactactgag cgtattcttt actacactgg taaaatccac aaaatcggtg aaactcacga
    95761 aggtgcgtca caaatggact ggatggagca agagcaagaa cgtggtatca cgatcacatc
    95821 tgctgcgaca acagctcaat ggaacaacca ccgcgtaaac atcatcgaca caccaggaca
    95881 cgtggacttc acaatcgaag tacaacgttc tcttcgtgta ttggatggtg cggttaccgt
    95941 tcttgactca caatcaggtg ttgaacctca aactgaaaca gtttggcgtc aagcaactga
    96001 gtacggagtt ccacgtatcg tatttgccaa caaaatggac aaaatcggtg ctgacttcct
    96061 ttactctgta agcacacttc acgatcgtct tcaagcaaat gcacacccaa tccaattgcc
    96121 aatcggttct gaagatgact tccgtggtat cattgacttg atcaagatga aagctgaaat
    96181 ctatactaac gaccttggta cggatatcct tgaagaagac atcccagctg aataccttga
    96241 ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt gctgaaactg acgaagaatt
    96301 gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa gaattgaaag ctggtatccg
    96361 taaagcgact atcaacgttg aattcttccc agtattgtgt ggttcagcct tcaaaaacaa
    96421 aggtgttcaa ttgatgcttg atgcggttat cgactacctt ccaagtccac ttgacatccc
    96481 agcaatcaaa ggtattaacc cagatacaga cgctgaagaa actcgtccag catctgacga
    96541 agagccattt gcagctcttg ccttcaagat catgactgac ccattcgtag gtcgtttgac
    96601 attcttccgt gtttactcag gtgttcttca atcaggttca tacgtattga atacttctaa
    96661 aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac gctaacagcc gtcaagaaat
    96721 cgacactgtt tactcaggtg atatcgctgc tgccgttggt ttgaaagata ctacaactgg
    96781 tgactcattg acagatgaaa aagctaaaat catccttgag tcaatcaacg ttccagaacc
    96841 agttatccaa ttgatggttg agccaaaatc taaagctgac caagacaaga tgggtatcgc
    96901 ccttcaaaaa ttggctgaag aagatccaac attccgcgtt gaaacaaacg ttgaaactgg
    96961 tgaaacagtt atctcaggta tgggtgaact tcaccttgac gtccttgttg atcgtatgcg
    97021 tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa gtatcttacc gtgaaacatt
    97081 ccgcgcttct actcaagcac gtggattctt caaacgtcag tctggtggta aaggtcaatt
    97141 cggtgatgtg tggattgaat ttactccaaa cgaagaaggt aaaggattcg aattcgaaaa
    97201 cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca gcggttgaaa aaggtttggt
    97261 agaatctatg gctaacggtg ttcttgcagg ttacccaatg gttgacgtta aagctaagct
    97321 ttatgatggt tcatatcacg atgtcgactc atctgaaact gccttcaaga ttgcggcttc
    97381 actttccctt aaagaagctg ctaaatcagc acaaccagct atccttgaac caatgatgct
    97441 tgtaacaatc actgttccag aagaaaacct tggtgatgtt atgggtcacg taactgctcg
    97501 tcgtggacgt gtagatggta tggaagcaca cggtaacagc caaatcgttc gtgcttacgt
    97561 tccacttgct gaaatgttcg gttacgcaac agttcttcgt tctgcatctc aaggacgtgg
    97621 tacattcatg atggtatttg accactacga agatgtacct aagtcagtac aagaagaaat
    97681 tattaagaaa aataaaggtg aagactaatc cgtcctcact ctagaaggaa gtcacttagt
    97741 ggcttccttt tgtctttaga aaatacctct aaatatggta aaatagtaga agaataatgt
    97801 gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa tcaattgggg atgcctgctg
    97861 aaatgagaca ggctcctgct ttagcacagg ccaatattga gcgagttgtg gttcataaaa
    97921 ttagtaaggt atgggagttt catttcgtat tttctaatat tttaccgatt gaaatctttt
    97981 tagaattaaa gaaaggtttg agcgaagaat tttctaagac aggcaataaa gctgtttttg
    98041 aaattaaggc tcggtctcaa gaattttcaa atcagctctt gcagtcctac tatagggagg
    98101 ctttctctga aggtccatgt gctagtcaag gttttaagtc cctttatcaa aatttgcaag
    98161 ttcgtgctga gggtaatcag ctatttattg aaggatctga agcgattgat aaggaacatt
    98221 ttaagaagaa tcatcttcct aatttagcca aacaacttga aaagtttggt tttccaactt
    98281 ttaactgtca agttgagaag aatgatgtcc tgacccaaga gcaggaagag gcctttcatg
    98341 ctgaaaatga gcagattgtt caagctgcca atgaggaagc gctccgtgct atggaacaac
    98401 tggagcagat ggcacctcct ccagcggaag agaaaccagt ctttgatttt caagcgaaaa
    98461 aagctgcagc taaacccaag ctggataagg cggagattac tcctatgatc gaagtgacga
    98521 cagaggaaaa tcgtctggta tttgaagggg ttgtttttga tgtggagcaa aaagtgacta
    98581 gaacaggtcg tgttttaatc aactttaaaa tgacggacta tacttcaagt ttttctatgc
    98641 aaaagtgggt taaaaacgag gaagaggccc agaagtttga cctcatcaag aagaattctt
    98701 ggctccgagt tcgagggaat gtggagatga ataacttcac acgcgatttg actatgaacg
    98761 tacaggatct gcaggaagtt gttcactatg agcggaagga tttgatgcca gaaggtgagc
    98821 gtcgggttga gtttcatgct catactaaca tgtcgactat ggatgctttg ccagaggtcg
    98881 aagagattgt tgcaacagct gctaagtggg gacacaaggc ggttgctatc acagaccatg
    98941 ggaatgtcca gtcctttcca catggctata aggcggctaa gaaagcggga atccagctga
    99001 tctatgggat agaagccaat atcgtggagg accgtgtccc tatcgtctat aacgaagtgg
    99061 agatggactt atcagaagca acctacgtgg tctttgacgt ggaaacgacg ggactttcag
    99121 ctatctataa tgacttgatt caggttgcgg cctctaagat gtacaagggg aatgttattg
    99181 ctgaatttga tgaatttatc aatcctgggc atcccttgtc agcttttact acagagttaa
    99241 ctggaattac agatgatcat gtcaaaaatg ccaaaccact agaacaagtt ttgcaagaat
    99301 tccaagaatt ttgcaaggat acggtcctag ttgcccacaa tgctgccttt gacgttggct
    99361 ttatgaatgc taattatgag cgtcatggtc ttccaaagat tagtcagcca gttattgata
    99421 cgctggagtt tgctagaaac ctctatcctg agtataaacg ccatggtttg gggcctttga
    99481 ccaagcgttt tggtgtggcc ttggaacatc accacatggc caactacgat gcggaagcga
    99541 ctggtcgtct gcttttcatc tttatcaaag aggtagcaga aaaacatggt gtgaccgatt
    99601 tagctagact caacattgat ctaatcagtc cagattctta caaaaaagct cggatcaagc
    99661 atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa tatctttaag ctggtttcct
    99721 tgtctaatac caagtatttt gaaggagtgc cacggattcc gagaacggtt ctagatgccc
    99781 atcgagaggg cttgatttta ggttcagcct gttcagaggg tgaagttttt gacgtggtcg
    99841 tttctcaagg tgtggatgcg gcggttgagg tggccaagta ttatgacttt atcgaggtca
    99901 tgccaccggc tatctatgcg cccttgattg ctaaagagca ggtcaaggat atggaggaac
    99961 tccagaccat tatcaagagt ttgatagagg ttggagaccg ccttggcaag cctgttttgg
   100021 ctacgggaaa tgttcactat atcgaaccgg aagaagagat ttatcgtgaa attatcgtcc
   100081 gtagtttggg acagggtgcg atgattaacc gaactatcgg tcatggtgaa catgcccaac
   100141 cagcaccact tccaaaggct cattttcgaa cgactaatga gatgttggat gaatttgcct
   100201 ttttgggaga ggaactggct cgtaaactgg ttattgaaaa caccaatgcc ttggcagaaa
   100261 tatttgaacc cgttgaagtc gttaagggtg acttgtatac gcctttcatc gacaaggctg
   100321 aagaaacagt tgctgagttg acctataaga aagcttttga gatttatgga aatccgctgc
   100381 cagatattgt tgatttgcgg attgaaaaag aattaacatc catactgggg aatggatttg
   100441 ctgtgattta tctggcatcg cagatgctgg tgcaacgttc taatgaacgg ggttatttgg
   100501 ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac catgattgga attacggagg
   100561 tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca gtacagtgag tttatcacag
   100621 atggttcgta cggttcagga tttgatatgc cccataagga ctgtccaaac tgtggtcaca
   100681 aactcagtaa aaacggacag gatattccgt ttgagacctt ccttggtttt gatggggata
   100741 aggttcctga tattgacttg aacttctcgg gagaagatca gcctagcgcc cacttggatg
   100801 tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg aacagttggt acggtagctg
   100861 ccaagactgc ctatggattt gtcaagggtt acgagcgaga ttatggcaag ttttatcgtg
   100921 atgcagaagt agaacgcctc gctcaaggag cggcgggtgt caagcggaca acaggccaac
   100981 acccgggggg aatcgttgtt attccgaact acatggatgt ctacgatttt acgcctgtcc
   101041 agtatccagc agatgatgtc acggctgaat ggcagaccac tcactttaac ttccacgata
   101101 tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga tgatccgacc atgattcgaa
   101161 aacttcagga tttgtctggt attgacccta ataaaattcc tatggatgac gaaggcgtga
   101221 tggcactctt ttctgggact gatgtgctag gggtaacacc tgaacaaatt ggaacgccta
   101281 cgggtatgtt ggggattcca gagtttggaa caaatttcgt acgtggaatg gtagacgaaa
   101341 cccatccgac aacctttgcg gaattgcttc agctgtctgg tctgtcccac ggtactgatg
   101401 tttggttggg gaatgctcag gatctgatta agcaaggaat agcggaccta tcgactgtta
   101461 tcggttgtcg ggacgacatc atggtttacc tcatgcatgc gggtctggaa cctaagatgg
   101521 cctttaccat tatggaacgg gtacgtaagg gtttgtggct aaagatttca gaagaggaga
   101581 gaaatggcta tatcgaagca atgaaggcta ataaggtgcc agagtggtat atcgaatcct
   101641 gtgggaaaat taagtacatg ttccctaagg cccatgcggc agcctacgtt atgatggcct
   101701 tgcgtgtagc ttacttcaag gttcaccatc ctatttatta ctactgtgct tacttctcca
   101761 ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg cttggaggtc atcaagcgca
   101821 gaatggaaga aatctctgaa aaacggaaga acaatgaagc ctctaatgtg gaaatcgatc
   101881 tctatacaac tcttgagatt gtcaatgaga tgtgggaacg aggtttcaag tttggtaaat
   101941 tagatctcta ccgtagtcag gcgacagagt tcctcatcga cggggatacc cttatcccac
   102001 catttgtagc aatggatggt ctgggagaga acgttgccaa gcaactggtg cgggcgcgtg
   102061 aagagggaga attcctctct aaaacagaac tacgcaagcg tggtggactc tcatcaacct
   102121 tggttgaaaa gatggatgag atgggtattc ttggaaatat gccagaggat aaccagttga
   102181 gtttgtttga tgagttgttt taaaaaattg cttaataatc tattaaaaga ggctaacgta
   102241 tatccaatag atttacatta gctttctttt ttgttaaaat agtctatgga aagagggtga
   102301 gagtatgtca aagatgagta taagcatccg tctggatagt gaggttaagg agcaggccca
   102361 acaggtgttt agtaatctgg gaatggatat gacaacagct attaatattt tccttcgtca
   102421 ggcaattcaa tatcagggat taccttttga tgttagacta gacgaaaatc ggaagttgct
   102481 ccaagcgtta acggatttag accaaaatcg taatatgagc cagtcttttg aatcagtctc
   102541 agatttgatg gaggacttac gtgcttaaga ttcgttatca taaacagttt aaaaaagatt
   102601 ttaagttggc tatgaagcgt ggtttgaagg cagaattatt agaagaagtt ttgaattttc
   102661 tggttcaaga aaaagaacat cctgccagat atcgtgatca ttcattgacg gcatccaagc
   102721 attttcaagg agttcgtgaa tgccataccc agccagattg gcttttggtt tataaagtag
   102781 acaagtcgga attgatttta aatttgctga ggacaggcag tcacagtgat ttattttaat
   102841 ctattttaag ggggttctca tgaaactaag aatatttgcg gaagataagc cggctaagaa
   102901 ggtatttgaa tatcaattag aacttgctga tcgtacaatt cttctatcga cagcactctt
   102961 gtcaggtgct attgctttag caggaatctt ttctgctttg aaagaaaaat aaaaatagaa
   103021 aagagaaaac agaatggttt taccaaattt taaagaaaat ctagaaaaat atgcgaaatt
   103081 gttggttgcg aacggaatta acgtgcaacc tggtcacact ttggctctct ctattgatgt
   103141 ggagcaacgt gaattggcac atctaatcgt gaaagaagct tatgccttgg gtgcgcatga
   103201 ggtcatcgtt cagtggacag atgatgtgat taaccgtgag aaattcctcc atgccccgat
   103261 ggagcgtttg gacaatgtgc cagaatacaa gattgctgag atgaactatc ttttggagaa
   103321 caaggctagc cgtcttgggg ttcgttcatc tgatccaggt gccttgaacg gagtggacgc
   103381 tgacaagctt tcagcttctg ctaaagctat gggacttgcc atgaagccta tgcgtatcgc
   103441 aactcaatct aacaaggtta gctggactgt agcagccgct gctggacttg agtgggctaa
   103501 gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt gatttccttt gggatcaaat
   103561 cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag gcttgggagg aacatgcagc
   103621 cattctcaag agcaaggccg atatgcttaa taaggagcaa ttttcagccc ttcactacac
   103681 agcgccagga acagatttaa cacttggttt gccaaagaac cacgtttggg aatcagctgg
   103741 tgctgtcaat gcacagggcg aagaattctt gccaaatatg ccgacagaag aggtcttcac
   103801 agcgcctgac ttccgtcgtg cagatggtta tgtcacttct acaaaaccgc ttagctacaa
   103861 cggaaatatc attgaaggca ttaaggtgac ctttaaggat ggacaaatcg tagatatcac
   103921 tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt gaaaatgcgg gtgcgcgtgc
   103981 cttgggtgaa tgtgccttgg taccagatcc aagtccaatt tctcagtcag gcattacctt
   104041 ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg gctatcggtg cagcctatgc
   104101 gactagcgtt gttgatggag cggagatgag cgaagaggag cttgaagctg cagggcttaa
   104161 ccgttcagat gttcacgtag actttatgat tggttctaac caaatggata tcgatggtat
   104221 tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg aattgggcaa attaaggaga
   104281 taatatgtta ggaagtatgt tcgttggtct cctagtggga tttttagcag gtgctatgac
   104341 caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt ctcggttgga tcggagcctt
   104401 tctaggtcac ttgctctttg gaacttgggg gccagtttta tcaggaacag ctattatccc
   104461 agcgatttta ggagccatga ttgttttagc tattttttgg agacgaggaa gttaatttcc
   104521 taaatctgat actcaatgaa aatcaaagag caaactagga aactagccgc aggttgctca
   104581 aa
//
LOCUS       DBERCW010000004        89752 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.004, whole genome shotgun sequence.
ACCESSION   DBERCW010000004 DBERCW010000000
VERSION     DBERCW010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 89752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.004"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..600
                     /locus_tag="ACL72M_000365"
     CDS             <1..600
                     /locus_tag="ACL72M_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0715555.1"
                     /translation="RYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPRSIETTSPA
                     REFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILAEIRNIHAF
                     DNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKVCARFSPAFKAYL
                     KTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            complement(799..2688)
                     /locus_tag="ACL72M_000366"
     CDS             complement(799..2688)
                     /locus_tag="ACL72M_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGS0715556.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNFFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2826..4391
                     /locus_tag="ACL72M_000367"
     CDS             2826..4391
                     /locus_tag="ACL72M_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS0715557.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4391..5131
                     /locus_tag="ACL72M_000368"
     CDS             4391..5131
                     /locus_tag="ACL72M_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0715558.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(5240..5455)
                     /locus_tag="ACL72M_000369"
     CDS             complement(5240..5455)
                     /locus_tag="ACL72M_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715559.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(6326..7576)
                     /gene="ilvA"
                     /locus_tag="ACL72M_000370"
     CDS             complement(6326..7576)
                     /gene="ilvA"
                     /locus_tag="ACL72M_000370"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGS0715560.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7626..7982)
                     /locus_tag="ACL72M_000371"
     CDS             complement(7626..7982)
                     /locus_tag="ACL72M_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS0715561.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(8220..8456)
                     /locus_tag="ACL72M_000372"
     CDS             complement(8220..8456)
                     /locus_tag="ACL72M_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715562.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(8563..9585)
                     /gene="ilvC"
                     /locus_tag="ACL72M_000373"
     CDS             complement(8563..9585)
                     /gene="ilvC"
                     /locus_tag="ACL72M_000373"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS0715563.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9651..10127)
                     /gene="ilvN"
                     /locus_tag="ACL72M_000374"
     CDS             complement(9651..10127)
                     /gene="ilvN"
                     /locus_tag="ACL72M_000374"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGS0715564.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10120..11820)
                     /locus_tag="ACL72M_000375"
     CDS             complement(10120..11820)
                     /locus_tag="ACL72M_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGS0715565.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(12020..13687)
                     /locus_tag="ACL72M_000376"
     CDS             complement(12020..13687)
                     /locus_tag="ACL72M_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGS0715566.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13690..14055)
                     /locus_tag="ACL72M_000377"
     CDS             complement(13690..14055)
                     /locus_tag="ACL72M_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0715567.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14212..14400)
                     /gene="rpmB"
                     /locus_tag="ACL72M_000378"
     CDS             complement(14212..14400)
                     /gene="rpmB"
                     /locus_tag="ACL72M_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGS0715568.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14519..15001)
                     /locus_tag="ACL72M_000379"
                     /pseudo
     CDS             complement(14519..15001)
                     /locus_tag="ACL72M_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
     gene            complement(15270..16814)
                     /locus_tag="ACL72M_000380"
     CDS             complement(15270..16814)
                     /locus_tag="ACL72M_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGS0715569.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            17027..17329
                     /gene="gatC"
                     /locus_tag="ACL72M_000381"
     CDS             17027..17329
                     /gene="gatC"
                     /locus_tag="ACL72M_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGS0715570.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            17329..18795
                     /gene="gatA"
                     /locus_tag="ACL72M_000382"
     CDS             17329..18795
                     /gene="gatA"
                     /locus_tag="ACL72M_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGS0715571.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWNHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18795..20237
                     /gene="gatB"
                     /locus_tag="ACL72M_000383"
     CDS             18795..20237
                     /gene="gatB"
                     /locus_tag="ACL72M_000383"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGS0715572.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20366..20926
                     /gene="efp"
                     /locus_tag="ACL72M_000384"
     CDS             20366..20926
                     /gene="efp"
                     /locus_tag="ACL72M_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGS0715573.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20948..21337
                     /locus_tag="ACL72M_000385"
     CDS             20948..21337
                     /locus_tag="ACL72M_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0715574.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            21330..21752
                     /gene="nusB"
                     /locus_tag="ACL72M_000386"
     CDS             21330..21752
                     /gene="nusB"
                     /locus_tag="ACL72M_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGS0715575.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     AVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21801..21995)
                     /locus_tag="ACL72M_000387"
     CDS             complement(21801..21995)
                     /locus_tag="ACL72M_000387"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGS0715576.1"
                     /translation="MILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFFNFL
                     NHAKPIWIFVYNYIYYHFFR"
     gene            complement(22050..22501)
                     /locus_tag="ACL72M_000388"
                     /pseudo
     CDS             complement(22050..22501)
                     /locus_tag="ACL72M_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22519..22704)
                     /gene="briC"
                     /locus_tag="ACL72M_000389"
     CDS             complement(22519..22704)
                     /gene="briC"
                     /locus_tag="ACL72M_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGS0715577.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(22863..23630)
                     /locus_tag="ACL72M_000390"
     CDS             complement(22863..23630)
                     /locus_tag="ACL72M_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGS0715578.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23627..24493)
                     /gene="accD"
                     /locus_tag="ACL72M_000391"
     CDS             complement(23627..24493)
                     /gene="accD"
                     /locus_tag="ACL72M_000391"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGS0715579.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24530..25897)
                     /gene="accC"
                     /locus_tag="ACL72M_000392"
     CDS             complement(24530..25897)
                     /gene="accC"
                     /locus_tag="ACL72M_000392"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGS0715580.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASRNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25909..26331)
                     /gene="fabZ"
                     /locus_tag="ACL72M_000393"
     CDS             complement(25909..26331)
                     /gene="fabZ"
                     /locus_tag="ACL72M_000393"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGS0715581.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(26328..26813)
                     /gene="accB"
                     /locus_tag="ACL72M_000394"
     CDS             complement(26328..26813)
                     /gene="accB"
                     /locus_tag="ACL72M_000394"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGS0715582.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26816..28051)
                     /gene="fabF"
                     /locus_tag="ACL72M_000395"
     CDS             complement(26816..28051)
                     /gene="fabF"
                     /locus_tag="ACL72M_000395"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGS0715583.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(28073..28804)
                     /gene="fabG"
                     /locus_tag="ACL72M_000396"
     CDS             complement(28073..28804)
                     /gene="fabG"
                     /locus_tag="ACL72M_000396"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGS0715584.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28838..29758)
                     /gene="fabD"
                     /locus_tag="ACL72M_000397"
     CDS             complement(28838..29758)
                     /gene="fabD"
                     /locus_tag="ACL72M_000397"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGS0715585.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTSLLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTTHLAHVEDQASLVALLKK"
     gene            complement(29751..30725)
                     /gene="fabK"
                     /locus_tag="ACL72M_000398"
     CDS             complement(29751..30725)
                     /gene="fabK"
                     /locus_tag="ACL72M_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGS0715586.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(30844..31068)
                     /locus_tag="ACL72M_000399"
     CDS             complement(30844..31068)
                     /locus_tag="ACL72M_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS0715587.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(31128..32102)
                     /locus_tag="ACL72M_000400"
     CDS             complement(31128..32102)
                     /locus_tag="ACL72M_000400"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGS0715588.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(32102..32536)
                     /locus_tag="ACL72M_000401"
     CDS             complement(32102..32536)
                     /locus_tag="ACL72M_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS0715589.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32630..33415)
                     /locus_tag="ACL72M_000402"
     CDS             complement(32630..33415)
                     /locus_tag="ACL72M_000402"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGS0715590.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33784..35148
                     /locus_tag="ACL72M_000403"
     CDS             33784..35148
                     /locus_tag="ACL72M_000403"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGS0715591.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            35151..35522
                     /locus_tag="ACL72M_000404"
     CDS             35151..35522
                     /locus_tag="ACL72M_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGS0715592.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35736..37010
                     /gene="serS"
                     /locus_tag="ACL72M_000405"
     CDS             35736..37010
                     /gene="serS"
                     /locus_tag="ACL72M_000405"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGS0715593.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVEAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(37035..37934)
                     /locus_tag="ACL72M_000406"
     CDS             complement(37035..37934)
                     /locus_tag="ACL72M_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGS0715594.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(38044..38592)
                     /locus_tag="ACL72M_000407"
     CDS             complement(38044..38592)
                     /locus_tag="ACL72M_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGS0715595.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38810..40132)
                     /locus_tag="ACL72M_000408"
     CDS             complement(38810..40132)
                     /locus_tag="ACL72M_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGS0715596.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFTFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(40223..40311)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40475..42811)
                     /locus_tag="ACL72M_000409"
     CDS             complement(40475..42811)
                     /locus_tag="ACL72M_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGS0715597.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKGQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQIGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42915..43463)
                     /locus_tag="ACL72M_000410"
     CDS             complement(42915..43463)
                     /locus_tag="ACL72M_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGS0715598.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43460..43762)
                     /gene="zapA"
                     /locus_tag="ACL72M_000411"
     CDS             complement(43460..43762)
                     /gene="zapA"
                     /locus_tag="ACL72M_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGS0715599.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43849..44730
                     /gene="rnhC"
                     /locus_tag="ACL72M_000412"
     CDS             43849..44730
                     /gene="rnhC"
                     /locus_tag="ACL72M_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGS0715600.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44734..45348
                     /gene="lepB"
                     /locus_tag="ACL72M_000413"
     CDS             44734..45348
                     /gene="lepB"
                     /locus_tag="ACL72M_000413"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGS0715601.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45582..47948
                     /locus_tag="ACL72M_000414"
     CDS             45582..47948
                     /locus_tag="ACL72M_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGS0715602.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNSIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47996..49279)
                     /gene="tig"
                     /locus_tag="ACL72M_000415"
     CDS             complement(47996..49279)
                     /gene="tig"
                     /locus_tag="ACL72M_000415"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGS0715603.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(50085..51221)
                     /locus_tag="ACL72M_000416"
     CDS             complement(50085..51221)
                     /locus_tag="ACL72M_000416"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGS0715604.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNDFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPTQSHEDSLFVMVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(51283..51720)
                     /locus_tag="ACL72M_000417"
     CDS             complement(51283..51720)
                     /locus_tag="ACL72M_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0715605.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(51722..53677)
                     /locus_tag="ACL72M_000418"
     CDS             complement(51722..53677)
                     /locus_tag="ACL72M_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0715606.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEIMKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(53701..55470)
                     /locus_tag="ACL72M_000419"
     CDS             complement(53701..55470)
                     /locus_tag="ACL72M_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGS0715607.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            55679..57019
                     /locus_tag="ACL72M_000420"
                     /pseudo
     CDS             55679..57019
                     /locus_tag="ACL72M_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(57147..58169)
                     /gene="cbpF"
                     /locus_tag="ACL72M_000421"
     CDS             complement(57147..58169)
                     /gene="cbpF"
                     /locus_tag="ACL72M_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HGS0715608.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRQEIAFRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWV
                     YDDGDWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQHLGNKWYYLRSSGAMATGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(58188..59009)
                     /gene="cbpG"
                     /locus_tag="ACL72M_000422"
     CDS             complement(58188..59009)
                     /gene="cbpG"
                     /locus_tag="ACL72M_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HGS0715609.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHSYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(59090..59329)
                     /locus_tag="ACL72M_000423"
     CDS             complement(59090..59329)
                     /locus_tag="ACL72M_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715610.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(59479..60237)
                     /locus_tag="ACL72M_000424"
                     /pseudo
     CDS             complement(59479..60237)
                     /locus_tag="ACL72M_000424"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(60238..60870)
                     /locus_tag="ACL72M_000425"
     CDS             complement(60238..60870)
                     /locus_tag="ACL72M_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0715611.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(60884..61879)
                     /locus_tag="ACL72M_000426"
     CDS             complement(60884..61879)
                     /locus_tag="ACL72M_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0715612.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(61876..62574)
                     /gene="liaF"
                     /locus_tag="ACL72M_000427"
     CDS             complement(61876..62574)
                     /gene="liaF"
                     /locus_tag="ACL72M_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGS0715613.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(62651..63661)
                     /gene="fni"
                     /locus_tag="ACL72M_000428"
     CDS             complement(62651..63661)
                     /gene="fni"
                     /locus_tag="ACL72M_000428"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGS0715614.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(63645..64652)
                     /locus_tag="ACL72M_000429"
     CDS             complement(63645..64652)
                     /locus_tag="ACL72M_000429"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGS0715615.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDILIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSFEEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(64639..65592)
                     /gene="mvaD"
                     /locus_tag="ACL72M_000430"
     CDS             complement(64639..65592)
                     /gene="mvaD"
                     /locus_tag="ACL72M_000430"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGS0715616.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEYLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(65574..66452)
                     /gene="mvk"
                     /locus_tag="ACL72M_000431"
     CDS             complement(65574..66452)
                     /gene="mvk"
                     /locus_tag="ACL72M_000431"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGS0715617.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITETCVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(66574..66798)
                     /locus_tag="ACL72M_000432"
                     /pseudo
     CDS             complement(66574..66798)
                     /locus_tag="ACL72M_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            67514..68389
                     /locus_tag="ACL72M_000433"
     CDS             67514..68389
                     /locus_tag="ACL72M_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGS0715618.1"
                     /translation="MYPPELDSKILSIIKKAVTIRTTHTYEYQYSLLFGDAGYLWLLL
                     HLFSISKNQYYLQLANVTAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLK
                     IFIHNSIGEIYHYFLQRDTAKESILDYSFAHGYCGIAYALFAYSKVLEPSMFYNDLHT
                     FHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLCMYDCDGNKDIISKYQEFVFN
                     HHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILACSERDDHGLLMFQGDSGKAD
                     LFDFGIGSMGYIGVY"
     gene            68432..69664
                     /locus_tag="ACL72M_000434"
     CDS             68432..69664
                     /locus_tag="ACL72M_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0715619.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(69782..70780)
                     /gene="cbpJ"
                     /locus_tag="ACL72M_000435"
     CDS             complement(69782..70780)
                     /gene="cbpJ"
                     /locus_tag="ACL72M_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HGS0715620.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(70798..71820)
                     /gene="cbpC"
                     /locus_tag="ACL72M_000436"
     CDS             complement(70798..71820)
                     /gene="cbpC"
                     /locus_tag="ACL72M_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGS0715621.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDPSNGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            complement(71918..72607)
                     /locus_tag="ACL72M_000437"
     CDS             complement(71918..72607)
                     /locus_tag="ACL72M_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0715622.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGIGYTMQE"
     gene            complement(72619..74043)
                     /gene="gndA"
                     /locus_tag="ACL72M_000438"
     CDS             complement(72619..74043)
                     /gene="gndA"
                     /locus_tag="ACL72M_000438"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGS0715623.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPYLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(74119..75513)
                     /gene="mapZ"
                     /locus_tag="ACL72M_000439"
     CDS             complement(74119..75513)
                     /gene="mapZ"
                     /locus_tag="ACL72M_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGS0715624.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLGKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(75526..76683)
                     /locus_tag="ACL72M_000440"
     CDS             complement(75526..76683)
                     /locus_tag="ACL72M_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGS0715625.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREMRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(76768..77148)
                     /gene="rnpB"
                     /locus_tag="ACL72M_000441"
     ncRNA           complement(76768..77148)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL72M_000441"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(77169..77498)
                     /gene="gpsB"
                     /locus_tag="ACL72M_000442"
     CDS             complement(77169..77498)
                     /gene="gpsB"
                     /locus_tag="ACL72M_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGS0715626.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(77568..78095)
                     /locus_tag="ACL72M_000443"
     CDS             complement(77568..78095)
                     /locus_tag="ACL72M_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGS0715627.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            78161..78757
                     /gene="recU"
                     /locus_tag="ACL72M_000444"
     CDS             78161..78757
                     /gene="recU"
                     /locus_tag="ACL72M_000444"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGS0715628.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            78754..80913
                     /gene="pbp1a"
                     /locus_tag="ACL72M_000445"
     CDS             78754..80913
                     /gene="pbp1a"
                     /locus_tag="ACL72M_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGS0715629.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(81080..86383)
                     /locus_tag="ACL72M_000446"
     CDS             complement(81080..86383)
                     /locus_tag="ACL72M_000446"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGS0715630.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDERDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KQALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEITVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASVTVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(86684..88666)
                     /locus_tag="ACL72M_000447"
     CDS             complement(86684..88666)
                     /locus_tag="ACL72M_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0715631.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKVLDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(88844..89623)
                     /locus_tag="ACL72M_000448"
     CDS             complement(88844..89623)
                     /locus_tag="ACL72M_000448"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS0715632.1"
                     /translation="MLGILYIFYSIIHFCIQKVAGASVRVPTMIFNLLNIYKFPLGVS
                     WYLYTLWSILIVYGLLSVVFKNRKSLLLVSVFAYIFTLFIQTDIFIVQRTLVWGICFF
                     LGSVLSEIHFDKINLKKFLFFFVLFDFIYMFAWFLFYEVGSKKDYVSYINPGLWGIAF
                     IVCVLVAFAIFPKMEKNFPKTFLYFTKYGKDSLGIYILHAPICSMIRILMLKVGINSV
                     FLHVVVGIVLGWYLSILATYILKKIPFLNIVLLPQKYIKLK"
     gene            complement(89529..>89752)
                     /locus_tag="ACL72M_000449"
     CDS             complement(89529..>89752)
                     /locus_tag="ACL72M_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715633.1"
                     /translation="AEDKAYNHALSKDRSKVENILAKVKTFKMFSTTYRNHRKRFGYF
                     RHTIYFLFNYSLLYSKGCGCLCPSTHYDI"
BASE COUNT        26496 a        20234 c        16399 g        26623 t
ORIGIN      
        1 cgctacccta atcctcagaa aaggattgag gcaggatttg ataagctgat agaaattaag
       61 cgattgaccg cttctaaaat tcaggatatc ctctcagtcg cacctcgttc tatcgaaaca
      121 acatctcctg ctcgtgaatt cgaaatcatc gaaatcatca aacattacaa gaggctcatt
      181 gacaaggcgg aaacatgtgt caatgacttg atggctgagt tcaactcagt catcacgacg
      241 gttactggga ttgggggtcg tttaggggcg gtcattttag ccgagattcg aaatattcat
      301 gcctttgata atcctgctca attacaagct ttcgctggac tggattcttc tatttatcag
      361 tcaggtcaga ttgatttagc tggaagaatg atcaaacggg gttcccctca tctgcggtgg
      421 gcactcatac aagctgccaa agtatgcgct cgcttttcac ctgcttttaa ggcctatctt
      481 aagactaagt tagaacaagg aaaacattac aatgtagcca tcatccacct tgcaaaaaaa
      541 cttatccgaa ccctgtttta tatcctaaaa aagagctgcc atttgacgaa caaaaagtga
      601 tgtaatttct gaaattaaca caggattacc tttgaaaaaa tggacttttt caagggcttt
      661 ttgccgtgct ctaaaatcat cgccaaatca tcaaattgaa ataagaaata gtttagataa
      721 aactattgac ttttcttata gtttgtcttt cttctatctt ccattatatc atactttttc
      781 agtctatggt agctctcttt aaaaggctcc gatactgccg ccacctccgc ctccagagaa
      841 gccaccgcca gaacttccac ttccagaaga tacggagtag gtacttgctg tatttgcgac
      901 actagcataa tggctcattt gcgcgcttga atgataaaac atactgtgcc agccataagc
      961 tacatagaga ttgatatctg gattttcaac ttgaatctga tgaaccttca tcaaatgact
     1021 aaccttgtcc gcatagccaa ataaggttgc atagaccaag agacgattcc aaacaacaat
     1081 actttccaat tcagccttat ccagtcgtgc aatctcacgt aacatatttt caaaactggt
     1141 ccagagatag tagacctcag ctcccgcttc atttagaaca ccatcacgat tatctagtcg
     1201 aagcttccaa taatagaaaa cagacaaaac taaccctaga aaaccaagta ttggcaaagg
     1261 gaggtaaaga tagccatgaa cgtctaaact gtacaagaac aaaccaaatc cgataaatag
     1321 gggcaagata gtcaagacac ccatacccac ttgcaaagtc ttttccaaac cagttaaagg
     1381 acgatagtaa tctgggagcc cccagaagga aactcgtttt ctcactcctt cttgcatctg
     1441 gttcaatacc tcttcaaaag aagatttgag ttgaagccct cttgcttgaa tccgtttttc
     1501 atcagaaact ttggctctac gataaagact atcagatacc ttgtaatccg caaaaaaatt
     1561 ggaaagagtg gcttcttttt tgcctgaaaa ggctagattt agacagtctc tctcaaatct
     1621 tgacaaacca tcttctttca ccaatctcaa gccaactgca tctccttctg aaataataga
     1681 gacattccca cggtctatca catctagcaa ggtagcttga ataagttggt caaaagtgaa
     1741 tttgccagcc cccttgacca agggactcac ttcctccaag gaggtcgagt agactgcttc
     1801 tgataaaacc ataggctcta attccattgg tggttcatag agacgatgat ttttggcata
     1861 tttgactgaa ggagtggtct ttcttctata aataaaatag aagcagacac tcaataacaa
     1921 ggagatagaa agtatcgaag ggaggaccca agtaacgagt tgtttactct gatctttttc
     1981 tctaacaatc gagtcttcta tcttattaaa ctcttctaaa cgattccctt tcaagccctg
     2041 atccctagcg ctagcaaaat cggtccgaga ccaataggca tgcaactcaa ctccacgctt
     2101 agccggaaga ttgtctaaac ggatagtata atcaaggtta ctcttttcaa tcgttccctc
     2161 tctaaaaagt ttccctgtat ggaaaaagag tttctcagcc cccttgtctc cccttacatg
     2221 aaattcaaac ttttcaatag actctgaact atctgtcaga ggttgccaat ttaattcagc
     2281 gatatcatca taaaggaaaa gtaaattttt taagttccag acgaggtcaa cttcaactat
     2341 gtcgccctcc tgacctggat tatagactct cacagtataa ccatccgctt cttctgttac
     2401 ttcgctagtc acatctgcta gttctgcacc gtttttcgca gcctgaacct ttggatgagg
     2461 gtcaatgtca aacccgctag gcatcttacc agcacgtcca agtcccacga tttggccctt
     2521 aaagtcctcc tcaaactggt aaactatctt ctgtctaaac tctgccgtat tatctgcatg
     2581 aatatacaaa tccccttgat aagagtttat cttgaaatca atggcaaaaa cagagagtgg
     2641 aagaaggcaa aacaagccta acaccagtaa gaaaaaagtt tttttcatca actaagcccc
     2701 ctttttatct ttcttatcat tatagcatct tttcgtaagt aaaggcttac ttatgttgaa
     2761 aaattacgca tttttcgata aaataggaga cagttatttt ttaatagatc agaataggag
     2821 aaatcatgag aaaaatatac ctatctattt tcacaagtct cttgctgatg ctaggacttg
     2881 tcaatgttgc tcaagccgat gaatatttac gcatcgggat ggaagcagca tatgctccct
     2941 ttaactggac ccaggatgat gatagcaacg gagctgtcaa aatcgatggg accaatcagt
     3001 atgccaacgg atacgatgtt caaatcgcca agaaaatcgc taaggactta ggtaaagaac
     3061 ctttggttgt taaaaccaag tgggaaggtc tagtccctgc ccttacttct ggtaagattg
     3121 acatgattat cgcaggtatg agtccaactg cagaacgcaa acaagaaatt gccttttcga
     3181 gcagttacta cactagcgaa ccagttttgc ttgtcaaaaa agattctgcc tacgcaagtg
     3241 ctaaatcttt ggatgacttt aatggtgcga aaatcacttc tcaacaaggt gtctacctct
     3301 acgacttgat tgcacaaatc ccaggtgcta aaaaagaaac agccatggga gacttcgctc
     3361 aaatgcgcca agctcttgag gctggtgtca ttgatgctta tgtttctgaa cgtccagaag
     3421 cactgactgc tgaagctgcg aactctaagt tcaagatgat tcaagtagaa cctggtttca
     3481 aaactgggga agaagataca gctatcgcta tcgggcttcg taaaaatgac aatcgtatta
     3541 gccaaatcaa tgccagcatt gaaaccattt caaaagatga ccaagttgcc ttgatggatc
     3601 gtatgatcaa ggaacaacct gccgaagcta caacaactga agagactagc agtagtttct
     3661 ttagccaagt cgctaaaatt ctttctgaaa actggcaaca actcttgcgt ggtgctggta
     3721 tcactctttt aatctctatc gtcggaacca tcataggtct cattattgga cttgccattg
     3781 gtgtcttccg tactgctcct ctctctgaaa acaaagccat ttatggcctt caaaaactag
     3841 tcggctgggt tctcaatgtc tacattgaaa ttttccgtgg tacgccaatg attgttcaat
     3901 cgatggttat ctactatgga actgcccaag ctttcgggat caaccttgac cgtacactgg
     3961 ctgctatctt catcgtttca atcaataccg gtgcctacat gactgaaatc gtccgtggtg
     4021 gtatcctagc agttgacaag ggacaatttg aagctgcgac tgctcttggt atgacccata
     4081 accagaccat gcgtaagatt gtcctacctc aggtagtccg taacatccta cctgcaactg
     4141 gtaatgaatt tgtcatcaat atcaaagata catctgtatt gaacgttatc tctgttgtcg
     4201 aactttattt ctcaggaaat accgtggcaa cacaaaccta tcaatacttc cagacattta
     4261 caatcatcgc cgtgatttac tttgtcctca ccttcaccgt aacacgtatc ctacgattta
     4321 tcgagcgccg aatggacatg gatacctata ctacaggtgc taaccaaatg caaacggagg
     4381 atttgaaata atgacacaag caatccttga aattaaacac ctcaaaaaat cctatggaca
     4441 aaacgaagtg ctaaaagaca tttcactcac tgtccacaag ggagaggtca tctctatcat
     4501 cggaagctct ggaagcggaa aatcgacctt cctacgctcc attaacctac ttgaaacacc
     4561 aactgatgga caaatccttt atcatggaca aaacgtcctc gaaaaaggct atgacctcac
     4621 gcaataccgt gaaaagttgg ggatggtttt ccaatccttt aacctctttg aaaatctcaa
     4681 tgttcttgaa aacacaatcg tcgctcagac aactgtccta aaacgcgaac gcacagaagc
     4741 tgaaaagatt gccaaagaaa acctggaaaa ggtcggcatg ggagaacgct actggcaagc
     4801 caaaccaaaa caactctcag gtggtcaaaa acaacgtgtg gccatcgctc gtgccctctc
     4861 catgaatccg gacgctattc tctttgatga accaacatca gctctcgatc cagaaatggt
     4921 tggagaagtc ctcaaaatca tgcaggacct ggctcaggaa ggcttgacca tgattgtcgt
     4981 aacccatgaa atggaatttg cccgtgatgt ctctcaccgt gttatcttta tggataaggg
     5041 cgtgatcgct gaagaaggta aaccagaaga cctcttcacc aatcctaaag aagaccgaac
     5101 aaaagagttc cttcaacgct atctcaaata aaaagaaaag gctgcatcaa ccgtgcagtc
     5161 tttttgctgt cctcaaaatg aaaaggcaga ttctctatct ctactacttg aaggtcaaga
     5221 atccgccgtt atccaaagat taatcttcaa atttttcata atttttttca tagaaatcaa
     5281 ttaagcctag ggctgtttca aatgaaatat tttttacttt tgcacgaccc tgcgccagag
     5341 caatgataga catttcacgc gcattcgttt ctttagagat acggtagcct gtgattttct
     5401 tatcacgaac ccagccaaca actgattcta ctttttcaaa gtttgactta gccatgtttt
     5461 tctcctattt tcttctttat aatatttaat tgtatacgtt tttactactt ttgtcaataa
     5521 aaaaaacata tattcaacga aaataattag ttcagaattt tcttacttcc tttttaaatc
     5581 cgataatata taggttttgc tagcctctac accataaata tttgctaata aaactactgt
     5641 attattaccc tcttaaggtg cgaaattatt caagttctta aaaaatgctt ctctatttcc
     5701 gtaagatagc ttatttcttc gatttaagaa ctgaagatga tagttctaac ctttagaaat
     5761 ccaagccttc actagctcaa aaactcctat ctttcttcct caataaatca tctgagagat
     5821 aggtatttct tatatccttc aaattcatca ctcctttgga tattgaggtg ctagcctaga
     5881 agcagacacc cgattatcta aaccatcctt aatagagatg acaagacaga taagctcagt
     5941 taattactta tatatctttt taatatggta tatttgtcaa caaaaagaaa tcaaatcata
     6001 ccttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaagt tgctcaaaac
     6061 actgttttga ggttgcagat agagctaacg tggtttgaag agattttcga agagtattaa
     6121 agacagtgtg actatgcttg tcaatagata ggaaatcaaa atgaaggatg gaaatctgag
     6181 ccaaacatca taagtgctat aatgaacaga agtaagaatt gcacgataag ttttctaaaa
     6241 ccataggaat cgtccccttt cttcatcttc attatagcat atatacatca gttgtacaaa
     6301 taatatgata tttttttatt agtcctcaga caagcatatt ataaagcgtt tcattaccat
     6361 ttaagttaat ataagctgga tcaaaacctt ccattctacg aatcaaacct gcataatcat
     6421 gcttatctgc taaagcgatc ccaatcaata ctgggcctgt tcccttgcta gctcgtttga
     6481 tatactcaaa acgtgtgata tcatcatttg gccccaggat atcatttaca aactcacgca
     6541 aagctcctgg acgttgtggg aaattgacca caaaataatg tttgatacca tcataaatca
     6601 aggcacgctc ttccatttct ggcatacggt tgatatcatt atttcctcca gaaatgatac
     6661 aacaaatggt tttcccctta atatattcag ctaaaacctc taaagaggcg atactagctg
     6721 ctccagcagg ttctgcgact atcccttgct tagagtaaag gtcaatcaag gtttcagaaa
     6781 tcaatccctc atcgacacct accaaagttt gaatatgttg acgagttgct tcataggtca
     6841 actgacctac cttttgcaca gcaatcccat ccgcaaattt atcaatttcc ttgagtttga
     6901 ctggacctcc agcctcaaag gcagctttca tggaacgcgc tccattcgcc tctactccga
     6961 taacctcaat ctctggactt gtttccttga tataggtaga aaccccggca atgagaccgc
     7021 caccaccaac aggaaccaag acagcatcaa aatcaatcga ttcttttcga gcttcttcta
     7081 aaatctcata agcaactgtt ccttgacctg cttgaacatg agcatcatca aaaggatcaa
     7141 taaaggtacg attttcagag actgtaaatt cttgagctgc tttggctgag gcatcaaagg
     7201 tatctccaac tagtttaata gttacaaaat ccccaccaaa aaagcgaacc tgaccaatct
     7261 tttgttgtgg cgtagtaatg ggcataaaga tagtagcagg aattttcatt tcattacaag
     7321 tataggctac tccctgcgca tgatttcccg cagaagcgca aactacccca cgttcacgtt
     7381 cttccttgct gagctgggaa atggcataat aggcaccacg aattttaaag gagcgaacac
     7441 gctgggcatt ttcttttttc aaataaatct tagcaccata cttctccgat aaataatgat
     7501 cgtaatccag tggagtattc acaaccacac cgttcaagac cttgtgagcc ttgattatat
     7561 cttttgaact taacatataa aacctctttt tctataaaaa acagtcacta atgactgttt
     7621 tttagttatt catctccgaa aatttcagta acactttcat ggtatttatg agccatacga
     7681 atcgaaaact ctttaggaag ttcataacga tttgtggaaa tccaatcata taaccattct
     7741 accaaacttt cttcactatc attacgatgg aagataaaat agtttaaaat ttctttatat
     7801 tctacatcat tcaaatccaa cgtgtctaca aattgactac gaggaacaaa attagaatct
     7861 aattttctta gttgatctgt caattctccc aattgtaaat ccaactgaaa aaatagtttt
     7921 tgcagttgcc tatcagtttc atcacatcct gtcttgatag aaaacaaatt ggtaatattc
     7981 atatgatttc aacccctaaa taagtacatc taatatccca cgaatagctg aagctaaagt
     8041 tttcgcagtc cagtcattta aacccgattc tttcaatcca gatgcaataa tttgctctat
     8101 ttgatataaa ccgccatcta tcgtctcatt tattctgcga agaggacctt caatatagga
     8161 taaagcttct ccgaatctaa cagctgattt aggtcctaat gatttaccaa ctatatttgt
     8221 taatattttt tatttctcaa aatccatttc gctatataac gagcagattt agtcgcacca
     8281 gctctctcaa acggagaatg aatttcaaga ccttcttctc tagctatttg tgccaatttg
     8341 aagaattgtt caaaggtcat atgcaaccta ccatcttcaa aattagcatc atcataaatg
     8401 ttaattacag cattttcatc atacgaccaa tctgctttat tttggtctgc tagcactatt
     8461 accgacggtg taattacatt atacaactag aaccaataat aacgatgcaa tttttctcat
     8521 aatctttttc ataaaatcat ctccagcgct atatatttct aattagttat agattttgaa
     8581 tgcatcatcg tcgtttttac caacgaatgg cattgcttta cgcaattctg caccaacttt
     8641 ttcaatttca aggttagctg cttgttcacg gtaagcagtc aattttggac gtccagcttt
     8701 atagtcattt acaaagtcat ttgcaaattt accattttgg atgtctgcca agacagcctt
     8761 catattttct ttaacttgtt cagtgattac acgtggacct gatacatagt caccgtattc
     8821 agcagtgttt gaaatagatt gacgcatttt cttgaatcca ccttcgtaga tcaagtcaac
     8881 gatcaatttc atttcgtgaa gaacttcaaa gtaagccaat tctggagcgt aacctgcttc
     8941 tgtcaagact tcgaaacctg cttcgataag ggcagtcaaa ccaccacaaa gtacagcttg
     9001 ttcaccaaac aaatcttctt cagtttcttc tttgtaagtt gtttcaagaa gacctacacg
     9061 agccgctcca acacctttac accagtccat agcaatgttt ttagcatttc ctgttgcatc
     9121 ttggtatact gcataaagag ctggaacacc aaatccttct tcgtaagtac gacgtaccaa
     9181 gtgtcctggt cctttaggag cacacatgaa gacatctaca tccgcaggaa ctttgataaa
     9241 ttcaaagtgg atgttgaaac catgggcaaa tccaactgcg tttccagctt ccaagtttgg
     9301 agcgatttct gcttcgtaca attcttgttg aatttcgtct ggcgccaaga tcatgataac
     9361 atcagccaac ttagtagctt ctgctactgt gtaagtatca aatccatctt cttttgcttt
     9421 atcaaaagat ttacctggac gtacaccgat aataacgtca cgacctgaat cacgcaagtt
     9481 ttgagcatgc gcatgccctt gtgaaccata accgataacg gcgatttttt taccgtcaag
     9541 tgctgctact ttaacatctt tttcatattc catttgaact gtcatagctt ttctctcttt
     9601 tctattattt attgcctttt aagctggttt aacaaattta agttggattt ttaatcgcgg
     9661 gtaaatccag ttgcacccgt tcgagcaata ttgcgaatac cgtatgggcg aatgactcgc
     9721 aatagggctt cgctcttttc tgcatttccc gtcatctgaa tggtaatcga gcttggcgct
     9781 acgtctacca ctgttgcacg gaaaggttga ataatcgcta aaatctcagc tctcttctca
     9841 gctggcgctg acatcttaac caaaatcacc tcgcgctcca aatgaggctt gtctgtaata
     9901 tctcgaatgc gaatcacatc aatctgacga ttgagctgtt tgatgatttg ctccacttca
     9961 tcatgagaag caacatcaat aataatagtg atacgcgata cattcggatc ttctgttgct
    10021 ccaacagaga tgctttcaat attaacctga cgacgagata ggacacctgt aaagcgattg
    10081 aggactcctg aacgattttg tagttttgct gttaacattc tacgcatgga actgcacccc
    10141 caacatctca tgattactct taccagccgg taccattggt aacacctgtt ccttacgaga
    10201 aatatctacc tcaattagca taggaacatc ctcagtgatg acttcaaggt cttgagccaa
    10261 ggtctcagga ttgtcaaact tatagttttt aataccataa gcctgcgcca tcaattggaa
    10321 atcaggaagg gtatcaaaga ccgactctga tgttctgcct tcatagaagg attcctgcca
    10381 ctggcgaacc attccgagtg aatgattgtt cagcataacc accttgattg gcaccttgta
    10441 aatattcaaa atagccaact cctggttggt catttggaaa ccaccatccc caacaaacaa
    10501 gactacttcc ttatctgggt tagcaatttt agcaccgatt gctgctggaa ttccaaagcc
    10561 cattgttccc aaaccacctg aagtcactaa ctgacgttca ttttggtagg gataatactg
    10621 agctgtccac atttggtgtt gaccaacgtc tgttaccaca atggcatctc cattcgtcaa
    10681 ttcaccaatt cgttcaataa ctgcttgcgg ttgaaccaca cgctctttct tgtcatacga
    10741 acgaacacga ttcttgtctt tagtgacttt ctcaatccac ttttcagtat tgttgtgaac
    10801 tgttggttct gctagcaaca tttgcaaggc cttcttagca tctccaacta caggaatgtc
    10861 tgcactgata atcttgccaa tctcagctgg gtcaatatca atgtgggcaa ccttagcatt
    10921 cttagcgaaa gtcttaggat tccccgtcaa acggtcatcg aaacgagaac caatactaat
    10981 cataaagtcc gcttccgtca tggcaatatt tgctgcgaat gacccgtgca tgcctcccat
    11041 tccaagaaag agtgggtgac tcgttgcaat cgttccttgt cccaaaagac tggttaccac
    11101 tggaatttga tagcgttctg caaattcatt tagttccgta gcagcctcag cataactaat
    11161 tccaccacca gctaacaaga ctggcttttt agccttggac aattgcttca agattttctt
    11221 gatttgcata tcattcggct caagagtcgg ctgataactt ggtaaattca cttctggtga
    11281 ataaatgaag tctgtttcta aagcagatat gtcttttggt aggtcaatta caactggccc
    11341 tggacggcct gtagttgcga tatggacagc ttccgtaatg atacgcggaa tatcagctgt
    11401 ctcacgaact tggtaattgt acttagtgat tggcatggta attcctacga tgtctgcctc
    11461 ctgaaaggca tccttcccaa tccctgctcg cgccacctga cctgtaaaga ccaaaagggg
    11521 aacgctatcg ctcatagcat ccgcaatccc tgtaatggca tttgttgctc ctggtccact
    11581 agtgacgacg gcaacaccca actttccagt tgatttggca tagccttcag cttcatgcaa
    11641 acaaccttgc tcatggcgcc ctagaatgtg gcgaatgcct ttaaaattat atatcgcatc
    11701 ataaaaaggc aaaaccgcac caccaggata accaaagatg gtatcaactc ctaaatcacg
    11761 aagtgtttcc aaaactaggt ccgaccccgt cttaggagat tctaaactga ttttctccat
    11821 tattcccctt tctttcctct taaaaataac ttgttactat cataccattt tttcaaaatt
    11881 tttcaagata aaagaagaaa ttttctgaat tttctatttt aacgtttatt tatgaatgtt
    11941 atttttgttt ttattaaaaa gataccgatt tcatttacta aaaagaaaaa agaactgatt
    12001 tctcagtcct tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac
    12061 cttggtgaat ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat
    12121 tggcaagttc ttcgcttccg tcttcaccga catagaaggt tacgatttca ctgtcttcat
    12181 ccaacatatg tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa
    12241 tttttccatc caccatacct aaattatcgt tttcatggat ttctaagcca tcgatcgttg
    12301 tatcacgcac ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac
    12361 gctcttggtt ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt
    12421 gaggaagagt gcgagcctct accactaccg ctggttgctc caaaacttct gccgcagatt
    12481 gagctgccat gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattaacct
    12541 gttcaacagc cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa
    12601 cataatccac gccttgagaa cagaagatat ctgctagacc tttaccagcc accacagcaa
    12661 tcaaagcata ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct
    12721 gtgcttcgtg ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga
    12781 gaccttcttg cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat
    12841 catcgttaac aacgaggaga gaatctccaa gctcatccaa gtagttacgg aattcatcgt
    12901 agtcaaaatc tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt
    12961 aaccaaacgt gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat
    13021 tgatcatctc actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc
    13081 cagtaagggc tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca
    13141 caacgccaac ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag
    13201 caccttccaa ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct
    13261 tagcaccgat agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca
    13321 ctgccttata ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta
    13381 actcgtcttt atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc
    13441 ctgagttccc acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa
    13501 ctgtagaagc tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat
    13561 ttgtcccagt atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt
    13621 gcttattcaa gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt
    13681 ttgacacggt tattctccta caactttgat attttgaatg tagacattta cagtctgagc
    13741 agtaattcca agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac
    13801 ttcactaatc tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc
    13861 ttcggctgcc tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa
    13921 attatctttg agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc
    13981 tccacctacg acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt
    14041 aatttttaca gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag
    14101 cccaagtgta aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt
    14161 tatacccaca ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg
    14221 ttcaacttta cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc
    14281 gataagaaca gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc
    14341 gtgtgaacgg ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat
    14401 tgtgttttcc tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat
    14461 gttatcacac tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa
    14521 tcaggtcttg cgtgacattt tctgctctcc acatgccatt gttgattaac agaacaccag
    14581 aattaaaatt atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt
    14641 ccaaatccca cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta
    14701 cacgagactc gcttacatac tttggaataa aatacctaaa aaaagccgca tatgaaagtc
    14761 cctcaaaggg gagacgataa cctttcagaa tactactgtc aatctgaaca ttcacaatct
    14821 cactattcaa agtctctagt cttttttcca tcaattggaa ccattctcgc ggaaggtcat
    14881 cattaaaaac ataaaactta agattataat gatgaacaca aagagatttt attgttgttt
    14941 caactttatc catataagca ttatctgcac ctaagacaat cgcttttttc tcttctttca
    15001 ctctttatct tatttctttt tattcccatc atattattcc catcatatgt ttctacgtaa
    15061 ccattatttt cgcctattcg ttcgtaaaac cataccagtg gagattttag atgaagtccc
    15121 attacggttt acaattttta cattacgaca cggagtttta caaatcgatt tcatttgcca
    15181 aacgtagtta gtgaggcagt tagctagttc gccaaatagc gactagcgtc caacaatttg
    15241 gaactttagc tccaattgtt ggtactgagt cacatcttct cctctaactc tacgtctgga
    15301 tacttgtccg caaaccagcg gagggcaaag tcattttcaa agagaaagac tggttggtca
    15361 aaacggtctt tggctaagat attgcgactt gacgacatcc gttcatccaa gtcctcaggc
    15421 ttgatccaac gaacggtctt tttacccatt gggctcatga ccacttccgc attgtattcg
    15481 ccttccatac ggtgtttaaa gacttcaaac tggagttgac caacagctcc cagcatgtac
    15541 tcacctgttt ggtaattctt ataaagctga acggctcctt cttgcaccaa ttgctcaatc
    15601 cccttgtgga aggatttttg cttcataaca ttcttggcag aaactttcat gaaaatttca
    15661 ggagtaaagg ttggcagtgg ttcaaattca aacttgtttt ttccaaccgt caaggtatcc
    15721 ccaacctgat aagtaccggt atcgtaaacc ccgataatat cacctgccac ggcattgatc
    15781 acattctcac gactttccgc cataaactgg gtaacattag atagtttagc ccccttacca
    15841 gtacgaggga gattgacact catgccgcgc tcaaattcgc ctgatacgat acggacaaag
    15901 gcaatacggt cacggtgacg aggatccatg ttggcttgga ttttaaagac aaagcctgag
    15961 aaatccttgt cataaggatc cacaatttca ccgtctgttt tcttgtgacc atgtggttct
    16021 ggagcaaact tgaggaagat ttcaaggaag gtctgcacac caaagtttgt cagggctgaa
    16081 ccgaaaaaga caggcgtcaa ttctccagcc agaatagctt cctctgaaaa ctcattccca
    16141 gcttcattta aaagctcaat gtcatccttg acttgctcgt agaaaggatt gctaccaaag
    16201 agtttgtccc cgtcttctag actggcaaaa cgctcatccc ctttgtaaag ctctaaacgt
    16261 tggttataga ggtcatacaa gccctcaaag gctttcccca tcccgatagg ccagttcata
    16321 gggtagctag caatgcccaa gatttcttcc aattcttgca agagatccaa aggctcacga
    16381 ccgtcacggt ccagcttgtt cataaaggta aaaactggaa tgccacgatg tttcacaacc
    16441 tcaaacaatt tcttggtttg agcctcgatc cccttggcag agtccacgac catgaccgca
    16501 gcatccaccg ccatcaaggt acgataggta tcttctgaga agtcctcgtg ccctggcgtg
    16561 tctaagatat tcacgcgctt gccgtcgtag tcaaattgca taacagatga agtaacagaa
    16621 atcccacgtt gcttctcgat atccatccag tcagatttag caaaagtccc tgttttcttc
    16681 ccttttaccg taccagcctc acgaatctca cccccaaagt agagtaactg ctcagtgatg
    16741 gttgttttcc ccgcgtccgg gtgggagata atggcaaagg tacgacgttt cttaatttct
    16801 tcttgaatat tcataagttc tctttctttg attctctatt tttcttgttt caatagctga
    16861 gaatgatttt tacattggat tttaccattc ctttcaatac tccattatat cggattttag
    16921 catttttttc aatttctatc tcttttcact tccccctccc ttatttatag gaaaatatgg
    16981 taaaatagaa cagactaaaa atcatcattt cacgaaagga tgcaagatga aaattacgca
    17041 agaagaggta acacacgttg ccaatctttc aaaattaaga ttctctgaag aagaaactgc
    17101 tgcctttgcg accaccttgt ctaagattgt tgacatggtt gaattgctgg gcgaagttga
    17161 cacaactggt gtcgcaccta ctacgactat ggctgaccgc aagactgtac tccgccctga
    17221 tgtggccgaa gaaggaacag accgtgatcg cttgtttaaa aacgtacctg aacaagacaa
    17281 ctactatatc aaggtgccag ctatcctaga cgatggagga gatgcctgat gacttttaac
    17341 aataaaacta ttgaagagtt gcacaatctc cttgtctcta aggaaatttc tgcaacagaa
    17401 ttgacccaag caacacttga aaatatcaag tctcgtgagg aagccctcaa ttcatttgtc
    17461 accatcgctg aggagcaagc tcttgttcaa gctaaagcca ttgatgaagc tggaattgat
    17521 gctgacaatg tcctttcagg aattccactt gctgttaagg ataacatctc tacagacggt
    17581 attctcacaa ctgctgcctc aaaaatgctc tacaactatg agccaatctt tgatgcgaca
    17641 gctgttgcca atgcaaaaac caagggcatg attgtcgttg gaaagaccaa catggacgaa
    17701 tttgctatgg gtggttcagg tgaaacttca cactacggag caactaaaaa cgcttggaac
    17761 cacagcaagg ttcctggtgg gtcatcaagt ggttctgccg cagctgtagc ctcaggacaa
    17821 gttcgcttgt cacttggttc tgatactggt ggttccatcc gccaacctgc tgccttcaac
    17881 ggaatcgttg gtctcaaacc aacctacgga acagtttcac gtttcggtct cattgccttt
    17941 ggtagctcat tagaccagat tggacctttt gctcctactg ttaaggaaaa tgccctcttg
    18001 ctcaacgcta ttgccagcga agatgctaaa gactctactt ctgctcctgt ccgcatcgcc
    18061 gactttactt caaaaatcgg ccaagacatc aagggtatga aaatcgcttt gcctaaggaa
    18121 tacctaggcg aaggaattga tccagaggtt aaggaaacaa tcttaaacgc ggccaaacac
    18181 tttgaaaaat tgggtgctat cgtcgaagaa gtcagccttc ctcactctaa atacggtgtt
    18241 gccgtttatt acatcatcgc ttcatcagaa gcttcatcaa acttgcaacg cttcgacggt
    18301 atccgttacg gctatcgcgc agaagatgca accaaccttg atgaaatcta tgtaaacagc
    18361 cgaagccaag gttttggtga agaggtaaaa cgtcgtatca tgctgggtac tttcagtctt
    18421 tcatcaggtt actatgatgc ctactacaaa aaggctggtc aagtccgtac cctcatcatt
    18481 caagatttcg aaaaagtctt cgcggattac gatttgattt tgggtccaac tgctccaagt
    18541 gttgcctatg acttggattc tctcaaccat gacccagttg ccatgtactt agccgaccta
    18601 ttgaccatac ctgtaaactt ggcaggactg cctggaattt cgattcctgc tggattctct
    18661 caaggtctac ctgtcggact ccaattgatt ggtcccaagt actctgagga aaccatttac
    18721 caagctgctg ctgcttttga agcaacaaca gactaccaca aacaacaacc cgtgattttt
    18781 ggaggtgaca actaatgaac tttgaaacag tcatcggact tgaagtccac gtagagctca
    18841 acaccaattc aaaaatcttc tcacctactt ctgcccactt tggaaatgac caaaatgcca
    18901 acactaacgt gattgactgg tctttcccag gagttctacc agttctcaat aaaggggttg
    18961 ttgatgccgg tatcaaggct gctcttgccc tcaacatgga catccacaaa aagatgcact
    19021 ttgaccgcaa gaactacttc tatcctgata accccaaagc ctaccaaatt tctcagtttg
    19081 atgaaccaat cggatataat ggctggattg aagtcaaact agaagacggt acgaccaaga
    19141 aaatcggtat cgaacgtgcc cacctagagg aagacgctgg taaaaacacc catggtacag
    19201 atggctactc ttatgttgac ctcaaccgcc aaggggttcc cttgattgag attgtatctg
    19261 aggcagatat gcgttctcct gaagaagcct atgcttatct gacagccctc aaggaagtta
    19321 tccagtacgc tggcatttct gacgttaaga tggaggaagg ttcgatgcgt gtggatgcca
    19381 acatctccct tcgtccttat ggtcaagaga aattcggtac caagactgaa ttgaagaacc
    19441 tcaactcctt ctcaaacgtt cgtaaaggtc ttgaatacga agtccaacgc caggctgaaa
    19501 ttcttcgctc aggtggtcaa atccgccaag aaacacgccg ttacgatgaa gcgaataaag
    19561 caaccatcct catgcgtgtc aaggaagggg ctgctgacta ccgctacttc ccagaaccag
    19621 acctacccct ctttgaaatt tctgacgagt ggattgagga aatgcggact gagttgccag
    19681 agtttccaaa agaacgtcgt gcgcgttatg tatctgacct tggtttatca gactacgatg
    19741 ctagtcagtt gactgctaat aaagtcactt ctgacttctt tgaaaaagct gttgccctag
    19801 gtggtgatgc caaacaagtc tctaactggc tccaagggga agtcgctcag ttcttgaatg
    19861 ctgaaggtaa aacactggaa caaatcgaat tgacaccaga aaacttggtt gaaatgattg
    19921 ccatcatcga agacggtact atttcatcta agattgccaa gaaagtcttt gtccatctag
    19981 ctaaaaatgg cggtggcgcg cgtgaatacg tggaaaaagc aggtatggtt caaatttcag
    20041 atccagctat cttgatccca atcatccacc aagtctttgc cgataacgaa gctgctgttg
    20101 ccgacttcaa gtcaggcaaa cgtaacgccg acaaagcctt tacaggattc cttatgaagg
    20161 caaccaaagg ccaagccaac ccacaagttg cccttaaact acttgcacag gaattggcga
    20221 agttgaaaga aaactagaca gaacaaaacc agccctaagg ttggtttttt cttctctacc
    20281 aactcccaat aactattttg gctttatttc cagagtattt tatggtaaaa tgaagagtaa
    20341 taatatttat taaagaggta aaaacatgat tgaagcaagt aaattaaaag ctggtatgac
    20401 ctttgaaaca gctgacggca aattgattcg cgttttggaa gctagtcacc acaaaccagg
    20461 taaaggaaac acgatcatgc gtatgaaatt gcgtgatgtc cgtactggtt ctacatttga
    20521 cacaagctac cgtccagagg aaaaatttga acaagctatt atcgagactg tcccagctca
    20581 atacttgtac aaaatggatg acacagcata cttcatgaat acagaaactt atgaccaata
    20641 cgaaatccct gtagtcaatg ttgaaaacga attgctttac atccttgaaa actctgatgt
    20701 gaaaatccaa ttctacggaa ctgaagtgat cggtgtcacc gttcctacta ctgttgagtt
    20761 gacagttgct gaaactcaac catctatcaa aggtgctact gttacaggtt ctggtaaacc
    20821 agcaacgatg gaaactggac ttgtcgtaaa cgttccagac ttcatcgaag caggacaaaa
    20881 actcgttatc aacactgcag aaggaactta cgtttctcgt gcctaatctc tagaaagagg
    20941 tcattctatg ggaattgaag aacaacttgg cgaaatcgtt atcgccccac gtgtacttga
    21001 aaaaatcatt gctatcgcta ctgcaaaggt agagggtgtt cactcttttt caaacagatc
    21061 agtgtctgat accctttcaa aactttcact cggccgtggc atttatctta aaaacgtgga
    21121 cgaagaactc acagcagata tctatctcta ccttgagtac ggagtaaaag ttcctaaggt
    21181 agcggttgct atccagaaag ctgtcaaaga tgccgtccgt aatatggctg atgtagaact
    21241 cgctgctatc aatattcacg ttgcaggtat cgtcccagat aaaacaccaa aaccagaatt
    21301 gaaagatcta tttgacgagg acttcctcaa tgactagtcc actattagaa tctagacgcc
    21361 aactccgtaa atgcgctttt caagctctca tgagccttga gttcggtacg gatgtcgaaa
    21421 ctgcttgtcg tttcgcctat actcatgatc gtgaagatac ggctgtacaa cttccagcct
    21481 ttttgataga cctcgtttct ggtgttcaag ctaaaaagga agaactagat aagcaaatca
    21541 ctcagcattt aaaagcaggt tggaccattg aacgcttaac gctcgtggag agaaacctcc
    21601 ttcgcttggg agtctttgaa atcacttcat ttgacactcc tcagctggtt gctgttaatg
    21661 aagctatcga gcttgcaaag gacttctccg atcaaaaatc tgcccgtttt atcaatggac
    21721 tgctcagcca gtttgtaaca gaagaacaat aaaaagaaaa agtgtttgat atctatcaaa
    21781 cactttttct ttgcctccca ctatctaaaa aaatgataat agatataatt gtaaacaaaa
    21841 atccagatag gttttgcatg attgagaaag ttaaaaaaac tatggcagag aatcgttaat
    21901 ctcagattgt cggtagaacg ataaacaagg gcaaaaaaga aaccaatcag actataatat
    21961 aataaactaa ttggatctct gtgagatagt atcaaatgac taagcccaaa gataaggcct
    22021 gataagatga catctaaata atacttggac tagggaaaga aggtattcat aaaataccct
    22081 ctatcaagag tctcctcaaa aacaggaccg atgattacag gcaggacaaa agataagata
    22141 gtcgataaaa aggttggttg tccatttgaa agaaccacgg taaaatactc atcatgaata
    22201 ttcctatgat taatcaaatg agcatagcgt gcccaaaaat taccgagaat ctgataaacc
    22261 acataagttg caaataagga gaagacaaat gaccagttcc agctcttttt cttttttaac
    22321 ctccaaatta atagaaaagg aaacttccca ctaatcccac tgttaaaata agagaataga
    22381 catcagctcc taaccctaaa atgatcgtca catacaatcc aattgtttgt ggtaaatagg
    22441 tagatagtaa aataataagc aaaaatattc caaattgtct tagtttcttt gtgtttctca
    22501 tcgtactttt ttgaaagatt accctgttcg gaagccgtac ttccaagcat ctatataaga
    22561 attaagtgcc ccttgcctca tatagggagc aaattctcta taatataacc atctactata
    22621 tccatcttcc caaacagcaa gaccacctga agtttgctcc aagtcctcag ttgaaataac
    22681 tgtaaatgtt tctgtacctg tcattgcaag taccttctta aaatagattg ttgtaggctc
    22741 acatttatag tatatttctt tttttgtcta ttttatagtc tatctcctca actggcaatt
    22801 tttcgacctg aattgcattt ttccataaaa aatgagacct ttctagtctc atttagtcat
    22861 tcttagtatt ttctaaatcg ttgatagcgt tcttccagca actcttctag cggtttttgt
    22921 gaaagtctag ccagctccgt ttggagttct tttttgacac tcttaattag ttctttacta
    22981 gaaagtccta cttcagaaat caccttatcc accacgtcca tttctaacag ttcatgcgaa
    23041 gtgattttca tcagttctgc tgcttccatg gcgcgagtac cgtccttcca taaaatggaa
    23101 gcaaagcctt ctggactgag aatggcatag atagaatttt ccagcatcca gacacggtcc
    23161 gcgacagcta gagccagagc cccgcctgaa ccaccttcac cgataataat ggcgataata
    23221 ggaactttca ggtcactcat ttccatgaga ttgcgagcga tagcttcccc ttgaccacgt
    23281 tcttccgctc cgacaccagg ataagcacct gctgtattga taaaggtcac aactggacgg
    23341 ccaaatttct cagcctgttt catcaaccgc agtgcctttc ggtagccttc tggatgtggt
    23401 tggccaaaat tccgtttgag gttgtcttgc aaactcttgc ctttttggat accaaccact
    23461 gttacagctt ggtctccaag ccaaccaata ccaccaacaa ctgcaccatc atcacgaaaa
    23521 gaacggtcac catgtaattg gataaattca tcaaaaatgc ctgtcgcaaa gtccaaggtt
    23581 gtcaagcgac tctgctcacg cgcttctctg actatttttg caatattcat ctaggactcc
    23641 ctccatgcaa tctgactagg ctagcaatcg tatctggtaa gtctcttctt ttgacaatag
    23701 catccacaaa gccatgttct aataggaatt ctgccttttg gaaatcctca ggcaagcttt
    23761 cacgaaccgt attttcaatc acacgacgcc cagcaaaacc aaccaagctc tgtggttcag
    23821 ccagaatgat atcgccttcc atagcgaaag aagctgtcac accaccagtc gttggatctg
    23881 tcaaaatggt caggtaaaag agaccagcat ttgaatggcg tttaaccgct gcagagatct
    23941 tagccatctg catgagactc atgattcctt cctgcatacg ggctccacca gaggctgtga
    24001 ataggacaac tggcaatttt tcgacagtcg catactcaaa caaacgagtg attttttcac
    24061 ctacaaccgt acccatagaa gccatgataa aattagaatc cataatccca agagccacag
    24121 tctgaccttt aataagagca gttcctgtca caacggcttc atgcagacct gttttttcac
    24181 gcatagatgc cagtttcttt tggtaaccag ggaaatgcaa gggatccttg ctttcaatcc
    24241 ctgtaaacaa ttctttgaag gttcccatat caatcgtcaa agccaagcgt tcttgggcag
    24301 aaatacgaaa ggtatagcta cagtgcggac agatacgttc acttcccaga tccttctgat
    24361 agatggtatg cttacagcct ggacactggg aaaataattc atctggaacc tctggcttag
    24421 cttgaggttt ttccctaacc gaacgattgg gattgattcg aatatactta tcttttttac
    24481 taaatagagc cattgattcc ccttttcggt ttaaactctt aaagtcattt tattcttttt
    24541 cttgatattt aggtaagaag gtttccatca agaaggaagt atcataatcc ccagcaatga
    24601 cattgcgatc tgaaatgaga tcaagctgga aatctgcatt ggtctgcact ccttcaatct
    24661 ctaattcata gagggcacgt tgcattttca tcaaggcgtc aaaacgattt tcgccgtgta
    24721 ctatgatttt ggcaatcata ctatcataat aaggcggaat ggtataacct ggataaactg
    24781 ctgaatccac gcgcaagcca actccaccac ttggcagata gagattagta atcttacctg
    24841 gacttggagc aaagttaaag gctgggtttt ctgcattgat acgacactcg atggcatgac
    24901 cgcgtaggac aatatcttct tgcttaacag acaaaggctg acctgccgca atgcaaatct
    24961 gttccttaac gatatcaaca cctgaaacaa actctgttac tggatgttct acctgaacac
    25021 gagtattcat ctccatgaaa tagaaatttc tacttgcttc atcaagaaga aattcaatgg
    25081 ttcctgcatt ctcatagcca acaaactctg ccgctcgaac agcagcagca cctatttcat
    25141 gacgcagcgt ttttccgatt gcaatcgagg gactttcttc caaaaccttt tggttattcc
    25201 tttgaagaga acaatcccgt tcacccaagt gaatcacatg tccatgctca tcacctagga
    25261 tttgaacctc aatgtgccga gctggataga taacccgttc tatgtacatg gcaccattgc
    25321 cataattggc cttggcctca ctagaggcag tttcaaaggc agaaacgagg tcatctggtt
    25381 tttcaacctt acgaatccct ttaccacctc cacctgctga agccttgagc ataacaggat
    25441 agccaatttt ttcagcaaca atcaaagctt cttcagagtt atgcacttct ccatctgaac
    25501 ctggtataac aggcacacct gctttaatca tctgagcacg cgcattgatc ttatccccca
    25561 tcatatccat aacatgacca gatggaccga taaacttgat acctacttct tcacacatgg
    25621 tcgcaaattt ggaattttca ctgagaaatc caaaaccagg gtgaatagct tctgcctcag
    25681 tcaagactgc agctgataga actgcattaa tattgagata agactctgtt gccttgccag
    25741 gaccaataca aactgcttca tctgccaaaa gcgtatgaag agcttcctta tcagcagttg
    25801 aataaaccgc taccgtcgca atccccaatt cacgtgccgc acggataata cgaaccgcaa
    25861 tttcaccacg attggcaatt aaaatttttc gaaacatgga gaacctcctt agttcccaat
    25921 tgcaaaagta aggataccac tggctgcaag cttgccatcc acttcagcct ttgcttcaac
    25981 cacagctatg gtgccacgac gttttacaaa agtcgctgtc ataaccaatt ggtcgcctgg
    26041 tacaacttgc ttcttgaact taaccttgtc cataccagcg taaaagacca gttttccttt
    26101 attttcaggt tttgataact ccaacacacc agcagtttgc gccaaggctt ccataatcag
    26161 aacacctggc ataactgggt attgaggaaa gtggccgtta aagaaaggtt cgttaatggt
    26221 cacatttttg atagcaacaa tggtatcctc gctcacttcc aagacacggt ccactagaag
    26281 cataggataa cggtggggaa gagcttcttt gattccttga atatcgatca tttgatacgt
    26341 accaatcctt taccaaactc aaccatttct tcgttagaga cgagaatttc cgttaccaca
    26401 ccatccttag gagctgggat ttcattcatg actttcatgg cttcgataat taccaatgtt
    26461 tgaccttttt tgacactatc accaactgta acgaaggcag gtttatctgg tccagcagcc
    26521 aagtaaacca ctccaacaag tggactctct acaagatttc cctcagtagc cacacttgct
    26581 tcagctggag ctggaacttc ttctgctaca gtctctgctg gagcagatgt aggagctact
    26641 ggactcggtg ttgctagaac gggtgctgga gcgacttgag ttgcaacttc aggcacaggt
    26701 cttgcttcat tcttgctaaa ctgcaactca tccgtcccat ttttataaga aaattctctc
    26761 aaacttgact ggtcaaattg agtcatcaag tctttaatat cgtttaaatt catacttatc
    26821 tattctccca acgtttgaaa gcaagaactg cattgtggcc tccaaaacca aaagtatttg
    26881 aaatagcgta tggaatttct ttctccaaac cttgtccata aacgacatta gcttcgatat
    26941 aatctgatac ttcacttgtc ccagctgtca ttggtacaaa gttatgacgc atagcttcga
    27001 tggtgacgat agcttctact gcacccgcag cccccagcaa atgtcctgta aaagacttgg
    27061 ttgatgatac aggtacttcc ttaccaagaa cagctacgat agcaccactt tctccttttt
    27121 cattggcagg agttgacgtt ccgtgagcat taacataggc tacttgctct ggagaaatct
    27181 cagcttcttc caaggctagt ttgatggcct tgatagctcc ctgaccttct ggatgtggag
    27241 aagtcatgtg gtaggcatca caagtatttc cgtaaccaac cacttcagcc aggatagtag
    27301 ctccacgttt ttcagcgtgt tcaagacttt ctagaaccaa catccctgaa ccttcaccca
    27361 taacaaaccc attgcgatcc ttatcaaatg ggatcgaagc acgagttgga tcctctgtag
    27421 tagagagagc tgttaaggct tggaaaccag cgatggcaaa aggtgtgata gaagcttctg
    27481 ttcctcccac caacatcaca tcttggaaac caaacttaat ggagcggaag gcatccccaa
    27541 tcgcatcatt tgatgaagag caggcagtat tgatagattt acaaacaccg tttgcaccaa
    27601 aacgcatggc tacattccca gaagccatat ttggtaaagc ttttggaaga gtcattggtt
    27661 tgacacgttt gggtcctttt tcatgaaggc gaagtacctg atcttcaatt tccttgattc
    27721 caccaatacc agatgcaacg ataacaccaa aacgatccct attaagagcc tctacatcaa
    27781 gattggcatg gtttacagcc tcttgggctg catacaaggc atataaagaa tagttatcaa
    27841 aacggttggt atcttttttt acaaagtatt tatcgaacgg aaaatcttgg atttctgccg
    27901 cattatgcac atcaaagtca ctatgatcaa attttgtaat gccaccaatg ccgattttcc
    27961 cagttgctaa actattccaa aattcttctg gtgtatttcc gattggagat gttactccat
    28021 aacctgttac cactactcga tttagtttca ttcttttcac ctctagcttt cgctacatac
    28081 ttaagccacc atcaatggca atcacttgac cagttagata atcttggcct gctaaaaata
    28141 ctgtcaaatc tgcaacctgc tctgcctgcc caaattcttt catcggaatc tgagctagtg
    28201 tagcttcctt aatcttatct gataagatag ctgtcatatc agactcaatc attcctggag
    28261 caatcacatt gactcgtata ttccgactag cgacctcgcg tgccacagac ttggtaaagc
    28321 caatcaagcc agccttagaa gcagcatagt tagcttgacc aatattcccc atcaaaccaa
    28381 caacactaga catattaatg atagcacctt ctctggcttt catcatcggt ttcaagactg
    28441 attgtgtcat attaaaggca ccagtcagat tgaccttgag cactttttca aaatctgctt
    28501 ctgtcatctt gagcataaga gtatcttggg taatccctgc attgttgacc aaaacatcta
    28561 ctgaacccag ttctgcaata gcttgatcaa tcatacgctt agcgtctgca aaatctgata
    28621 catctcctga aatgggaacc accttgatac catagtttga aaactcagcg agcaattctt
    28681 ctgagattgc cccacgactg tttaagacaa tgttggctcc tgcttgagca aacttgtggg
    28741 cgatggcaag accaattcca cgactcgaac ctgtaataaa gatattttta tgttctagtt
    28801 tcattttttt cctttcaaaa cttctactta ttttagtcta tttttttaaa agtgctacta
    28861 aactcgcttg atcttccaca tgagctaagt gagtagtttg atcaattttt ttaacaaaac
    28921 ctgacaagac tttccccggt ccaatctcga taaagttgct tatgcctgct tcttgcatga
    28981 ccccaatact ttcatagaaa cgaacgggtt ccttgacctg acgcgtcaag agctgagcaa
    29041 tgtcctcttt ttgcatcaca gcagcttctg tattgccgac taggggacaa gtaaaatctg
    29101 aaaaacttac ctgagccaga gtttcagcta gtttctggct agcaggttca aggagagagg
    29161 tgtgaaaggg acctgacacc ttaagaggaa tcaagcgttt ggcacctgct tcttgcaaaa
    29221 gttcaaccgc tcgatcaact gcaaccactt ctccagcaat gacgatttgt gcaggtgtgt
    29281 tatagttggc tggagtaacc actccaagtt cagaagcttt ttgacaggct tcttcaatga
    29341 cctctactgg cgtattgaga actgctacca tcttgccaga gtcagcagga gccgcttctt
    29401 ccatataggc tccacgctta gctaccaagg caaccgcatc ttcaaaatcc aaggcgccgc
    29461 ttgccaccaa ggcagagtat tctccaagag acaaaccagc aaccatatca ggctgatagc
    29521 ccttttcttg caataaacgg tagatagcaa ccgaagtcgc tagaatggct ggttgcgtat
    29581 agcgggtctg attgagtttg tcttcttccg tatcgatgag ataacgcaaa tcataaccta
    29641 gcacctgact cgctcgatca atcgtttctt taacaatcgg atactgatca tagaaatccc
    29701 gtcccatccc tagatactgg gcaccttgac cagcaaataa aaaggctgtt ttagtcattt
    29761 cttacaactc ctgtccagcg agaggcttct tcttgaattt tcttagcggc tccgtaatac
    29821 aaatctttta ggatttcttc agctgtttct tctttagaaa caagccctgc gatttgacct
    29881 gccatgacag agccaccctc cacatcaccg tgaacaactg ctttggctag ggcacctgct
    29941 cccatttgtt caaagatttc taaatcagga tcttcctgct taaaggcatc tttttcagcc
    30001 agttcaaaat ctctagtcaa ctgattttta atagcacgaa cagcatgacc aaagtgctga
    30061 gctgaaatcg tagtgtcaat atcccttgct tttaaaattt tctccttgta gtttggatgg
    30121 gcattcgact cttttgcaac tacaaaccgt gtccccacct gtacagcctc tgcacctagc
    30181 ataaagccag ccgcagcacc ttcaccatcc gcaattcctc ctgcagcaat aacaggaata
    30241 gatacagctg tggctacctg tcgcaccaag gtcatggttg ttaatttacc gatatgcccc
    30301 ccagcttcca ttccttctgc aataacagcg tctgcaccga ttttttccat gcgtttagct
    30361 aaagcgacac taggaacgac aggaataacg attatcccag cttcatggaa acgttccata
    30421 tacttgcttg gatttcctgc tcctgttgtg acaactttaa caccttcttc aataacgaga
    30481 tccacgatat cttccacaaa gggagataag agcatgatgt tgaccccaaa gggtttatca
    30541 gtcaatgatt tgattttatc aatattggcc ttgacaactt ctttcggggc atttccccca
    30601 ccgataattc ctaatcctcc agccttggaa acagcccctg ccaaatcacc atcagcaacc
    30661 caggccatcc ctccttggaa aataggatag tcaatcttca ataattctgt aatacgcgtt
    30721 ttcatagtgc ctccaacctt ccttgcttac gtaatagttc gatttcacca taatttgaca
    30781 gtcaaactat tacctaaaca agagggagtg ggtttctccc tactccttct actaatattc
    30841 tgcttatttt gcttgctctt caacgtaagc aaccaagtca ccaactgttt tcaagtcatt
    30901 ttctgcttcg atttggatat caaaagcatc ttcgatttct gagattactt ggaacaagtc
    30961 caatgaatct gcgtccaaat catcaaaagt tgattcaagt gttacttctg atgcgtcttt
    31021 tccaagttct tcaacgataa tttcttgtac tttttcaaat actgccatga taggactcct
    31081 ttaaaataaa tagttttttt ataacaatgt gttcaccaca tgattaccta aattgtaaga
    31141 atgagcgtgc cccaggtcaa acctccaccg aagcctgata gaagaacagt ctggctacca
    31201 tctaaaggga tgagaccttg ttctacacac tctgaaagta aaatcgggat actggctgca
    31261 ctggtattgc catattccat catattggct ggaagtttgg ctcggtcaac accaattttt
    31321 ctagccatct tatccaaaat acggtcattg gcttgatgaa gtagcagata atccaagtct
    31381 gtcacctcta taggagattc atcaatagtc tgcttgatag acttggctac atctcgaatg
    31441 gcaaaatcaa agactgtgcg tccatccatc ttcaaaaacg aatctgcact ttcttgatct
    31501 gaaaatggag aatgcaaacc tgaatgccca taagttaaac actcgctgcg acttccatcg
    31561 ctattgagac tctcagctaa gaaatgctct tgctcgctag cttctaacaa gacaccacca
    31621 gcaccatctc caaacaacac agctgttgat cgatccgacc aatcgactgc cttagagagg
    31681 gtttcactac caatcaccaa gcctttttga aagcgaccag aagcgataaa cttttcagca
    31741 gttgaaagag caaatacaaa tccactgcaa gccgcggtta agtcaaaagc aaaggcttta
    31801 ttagcaccaa tattagcttg aacacgagca gctgtagagg gcatcatcga atctggagta
    31861 atggtagcta ggatgataaa atccagttct tctcctgtta ttccagcttt tgccatcagt
    31921 ttcttagcaa cctctgtagc caaatcactg gtagattctg ttcttgaaat atgcctttgt
    31981 cgtattcccg ttcgacttga aatccactca tcattggtat ccataatctg agccaagtcg
    32041 tgatttgtaa ccacttgctc tggcacataa tgagcaacct gacttatttt tgcaaaagcc
    32101 attatttcaa atcctccaaa aattggtaaa gattagtcaa gcctttaccc atgacagcaa
    32161 tttcttcctc gctcatgcca tcaataattt tttctaccat ggccttgtgg aagcgtttat
    32221 gcagtctatg aatcaagcga cccttctttg tcaaatgcag atgcaccaca cgacgatcct
    32281 gttctgaccg aactcgctca atgtagccct tacgctctaa attgttcaaa cttgtcgtaa
    32341 cagttccaag agttaccatt aactcttttg acacttgact tggagtcaca tctggagcct
    32401 taccgatgac atcaattgta tgcatttctt tgatggagat atccttaaaa cgactacctc
    32461 tcaagttcac ttcctcaatt acaaggacat tgttaaatat agatgttaaa tattcattga
    32521 ttcgttggta gtccattttt catatccctc cttcttcaaa aaacttttac aatcaaaaca
    32581 tttgacagaa agaattatat caaaattcaa agaatgatgc aagtattttt tattttcctg
    32641 taaatttagg tcttcttctc tccgaatgag ctcgcactcc ttctttgaaa tcctctgttt
    32701 gagctaagga tttctgtagg ttcagttcta aagtagcgta accctgccag tctttaaatt
    32761 ggctctccca aaccaacttc ttaatggcag cataggaatt acttgaagca cgtcttaatt
    32821 ttttaagaag ctgttctctc gtcttttcaa gtttttcagc ttcagaaacg cggtaaacca
    32881 acccccattc tagggctttt tctgccgtta aagcctctcc tgtcatagct aattgagcag
    32941 cacgcgtcac accgatactg cggctcaaga gatgaattcc ccctgcatct ggagccaaac
    33001 caacaccaac aaaggcttgg ataaacttag ccttatccgt cgccaaacag aaatctgccg
    33061 caacagccat attcgctgcg gcacctgcaa cagcaccgtc aacttccatt aaaacaggtt
    33121 tggctatttg cttgatttta taagaaatcg tattgaccaa ctctgcgatt tttgtcaatg
    33181 atggaatatc atcctcatcc actgcccgct tcatctctac caaatctccc ccaactgaga
    33241 agacctttcc attggcattg attaagataa aatgcacagc tggattttct tctgccaaag
    33301 tcagagcttc taaaatctcc tcacacatgg gaatatgaaa accatttgcg acctcaggac
    33361 ggttcaaggt aaggattgcc aagtcctctt caagctgata aataatgtgt tccatcaggg
    33421 ctccttttta ttttataagc agtttatact cttcgaaaat ctcttcaaac cgcgtcagct
    33481 tccatctgca acctcaaaac agtattttga gctgacttcg tcagtcttat ttacaacctc
    33541 aaagcagtgc tttgagcagt ctgcggctag cttcctagtt tgctctttga tttcattgag
    33601 tgttaaatta tttcactgtc aaagtatatc ttttttagga gcagaaagca agaaaaaatc
    33661 gactgaaagt gtctcagccg ataagaaagg ctcgctttag gctagaaagc atcttatttt
    33721 cttcattgaa aaaagccttt ctttctgcta taatcgtata aaatacttac tttaggagtt
    33781 cttatgaaag ttgttaaatt tggaggtagt tctcttgcct ctgctagtca attagaaaaa
    33841 gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt
    33901 aaacgcaatg ctgaagatac taaggttacg gatgccctga ttaaatacta ccgcgactat
    33961 gttgcgggta acgatattag caagagccaa agctggatta tcgaccgcta tgctgctatg
    34021 gttagtgaat tgggactaaa accagctgtg ctagaaaaaa tttctaaaag cattcacgcc
    34081 ttggccactc ttcctattga agaaaatgaa tttctctacg atactttcct agcagccggt
    34141 gaaaataaca atgccaaatt gattgctgcc tactttaacc aaaatggtat cgatgcacgc
    34201 tatatgcacc ctagagaagc tgggattgtg gtcacaagtg aacctggtca cgctcgcatc
    34261 attccatcaa gttatgacaa gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt
    34321 cctggtttct ttggtgtcac taaggaaaat caaatctgta ctttctcacg tggaggttct
    34381 gatattacag gttctatcat tgctgctggt gtcaaagccg acctctatga aaactttacg
    34441 gacgttgatg gtatctttgc agcccaccct ggtattatcc accaaccaca ctcgattcct
    34501 gagttgacct accgtgaaat gcgcgagttg gcctatgcag gcttctcagt ccttcatgac
    34561 gaggctcttc ttcctgccta ccgtggaaaa attcctctgg ttatcaagaa taccaacaac
    34621 cctgaccatc caggtactcg tatcgttcta aaacacagta atgatgaatt tccagttgtg
    34681 ggaattgctg gtgactcagg ctttgtcagc attaacatgt cgaaatacct catgaaccgt
    34741 gaggttggat ttggccgcaa ggttctgcaa atcctggaag aacttaacat cggttgggaa
    34801 catatgccaa caggtatcga cgatctttct atcattctcc gttctcgcca actaactccc
    34861 atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa
    34921 atcgaacacg acctttctat cattatgatt gttggtgaaa aaatgaagag ccacatcgga
    34981 gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa tcaacatcca gatgatgtct
    35041 caaggttcta gtgaagtttc tattatgttt gttgtcaata aagaccaaga gaaagcagca
    35101 attaaagccc tctacaatgc cttttttgga gaaagtaagg aagactaagc atggcccaat
    35161 cacttaacaa aacagtactc ctcagtacga caggcacttc ctacctctct atcgctggga
    35221 aagttgggaa attccttgtc ggagatcagg ctttggaatt ttacccagat gtcaatgtcg
    35281 aacaatttat ccagattcct tggagccata tcaatcagat tggagccaat gtcactggac
    35341 gcaaaatcag ccgccacttc gaagtcttta cagacaaagg aaaattcctc tttgcttcaa
    35401 aagactcagg tgccattctc aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca
    35461 aacttccgac cctgattcag acaattagcc aaaaatttaa aaatctattt gcaaaaaagt
    35521 agaaacttta gtataatcat agcaacggat aagtaggtta tcttcttctt tcagaaagtc
    35581 tgcgggtact gcgagcagat aggggggata ggtgaaattc taccgttagt aacaattaca
    35641 tacacaatca agtgcacacc tgtgaagttg gatggaaccg tggccctgcc actccaacgt
    35701 tttgtcaggc gtgctttttt cataaaggag ttcttatgtt agatatcaaa cgtattcgta
    35761 cagattttga agctgtcgca gaaaaattag ctacacgtgg tgtagaggct gctgtcttga
    35821 atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca
    35881 aagcagaacg taacacagtt tctgctgaga ttgcccaagc taagcgcaac aaggaaaata
    35941 cagatgacaa gattgctgcc atgcaaaatc tatctgctga ggttaaagcc ttggatgctg
    36001 aattggcaga aatcgatgct aaattgacag aatttacaac gactcttcca aatatcccag
    36061 ctgacagcgt tcctgttggg actgacgaag acgacaatgt ggaagttcgc cgttggggta
    36121 ctccacgcga gtttgacttc gaacctaaag ctcactggga tctcggtgaa gaccttggta
    36181 tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc
    36241 tcggtgctcg tttggaacgt gctatctaca actttatgtt ggatgaacat ggaaaagaag
    36301 gctatactga agtcatcaca ccttacatag tcaaccatga ttctatgttt ggtactggtc
    36361 agtatccaaa atttaaggaa gatacttttg aactcagcga taccaacttt gtcttgattc
    36421 caactgctga agttcctctg acaaactact accgtgatga aatcttagac ggcaaagatc
    36481 ttccaatcta cttcactgcc atgagtccgt cattccgttc tgaggctggt tctgccggtc
    36541 gtgatacgcg tggcttgatc cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg
    36601 ccaaaccaga agaatcttac gaagaattgg aaaaaatgac agccaacgct gaaaacattc
    36661 ttcaaaaact caaccttcca taccgtgtcg ttgctctctc tactggagat atgggcttct
    36721 cagctgcgaa gacttacgac ttggaagtgt ggattccagc acaaaacaat taccgtgaaa
    36781 tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg
    36841 atgaagcaga tggcaaggtg aaactccttc ataccttgaa cggttctgga cttgcagttg
    36901 gacgtacagt ggctgcaatt cttgaaaatt accaaaatga agatggttct gtgaccatcc
    36961 cagaagcact tcgtccatac atgggtggag ctgaagtcat caaaccataa aaaataaggt
    37021 ttagctattt ctagctagac cttttttcgt aaccaaatca gataagcacc tagtacaaag
    37081 aataaaatag ttaggcatat aatggtttca gccaatacca ggtaatccag aaatggaagt
    37141 ttcaaaattc cctgagccat cttgagcgag gtcgctgtga taatggttgg gaaggtgagg
    37201 gctgagaagg ctggttgaaa accttgtttt aaaatgttgg gcagacgagt taaaacaaag
    37261 aaaaagaagg attgagaagc caaaatcatg acaatcaaga cccaagtcgg caggctggtt
    37321 cctcctactc gaactagaga agccaagagt agagagaaag gagcacagta gattccttct
    37381 tgtccaagca aggctagtgg gagtggatgt ttctttaaat cgctataaat aaggggatag
    37441 agatagaagg tcaagagaaa accaaaactc aaggtcgcat aggcaatttc gataatacct
    37501 accagaggat aggtcaaggc agccactgct atccccacat agagaaccgt ccaacttgga
    37561 gtggcatgaa ccctccgccc tgaacaagca aacttgatgg taaaaccagc aatcaaggtc
    37621 aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat
    37681 acgcgaaaga cataggtcga taaaatcatc ccagccatag gaaaggttgc cattcctgac
    37741 aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc aattaaagag atgcagaatt
    37801 agaaagtaaa tccataaaac caaaccagtc agactaaaaa gatgggatag aaccggcaac
    37861 gtatctaaaa taagatttcc agctcctgcc aaacctagca aacaacctga aaatactaag
    37921 gggagttttt tcatcctaac ctccaataat catgttagtt tcagtataac ataaaagcgc
    37981 ttaaatgagg atttaaaaaa acgaagtccg cttatttcag acttcatttt actcagatat
    38041 gaattaggca taaggttgca attctggatt aattggtgta ttagctaagt tgttggcata
    38101 gttacagagg attgctaggc tgacaccaaa aaccacatcc aaggcatttt gttgagtgta
    38161 gccagcttct aaaaactcag acaaggcttc atctcctaca cgacccttgg tattgataac
    38221 tgccaaggta aacttagcta gggtatccaa tttaggatct gtttcaattg gagtacgatt
    38281 gcgaagagct tgaatcaagt catcattcat ctggatttgt ttgatggaaa aggctgtgtg
    38341 acctgcgaca cagaaggcac aaccattggt cacggctgcc gtgatttgca ccacttcacg
    38401 ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag acaatttggt aggcttctaa
    38461 aacagtcggg gcattggcca agagaccgat taggttggga atatagccat tgttgtcttt
    38521 ttctactgtt tcaagaattt ctttcacttc tgctggtgct gactctactg tatggatagt
    38581 aaatgttgtc ataagatacc tcttttctta ttattgacac taatattatt ggaaaatctt
    38641 ataaaatcct gattcctaag tttatctaag ataaagcttt attctctcat aagattttcg
    38701 ttgttatatt agtttatcac acttccaatc acttgcataa tatatattat atatcaggct
    38761 gataaaaatt atttataggc aaaaaaatca cacgagctgt gtgattccat tatttgtcaa
    38821 aatacttttt agtttcagca ataacgactg gcgacaagac caagagggca atcaagtttg
    38881 gcagagccat caaggcgtta acgatatctg cgataatcca gaccatatcc aactcgataa
    38941 atcctcctaa caagaccatg agcacaaaaa acacacggta gagccagata aagcgagccc
    39001 caaagaggaa ctcaaaacag cgttctccgt aatagttcca acctagaatc gttgtaaagg
    39061 taaaaagtac aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga
    39121 aagctgactg agtcaaggca accccattca agtcaccact ccaaactcca gttaccaaga
    39181 tggtcaaacc agttagagta caaatgatga gggtatcaat aaaggttcct gtcatggaaa
    39241 tcaaaccttg ctctactggt tcatttgtct tggcagctgc agctgcaata ggagcagaac
    39301 ccagaccaga ttcgtttgag aacacaccac gcgccacacc attttgaata gccatccgaa
    39361 cgctagcacc agcaaatcca cctaccgcag caaggggact aaaagctgag gtaaagacta
    39421 aagcgattgt gccagggatt tttccgatat taaagaaaat aactgtaaga gttcctaaga
    39481 tataaatgag ggccataaaa ggaacaacag tagttgaaac cttagaaata gacttgagtc
    39541 caccaaagac tgcaatcgct acaaagacag acaagacgag agctgtgatg gctggcgaaa
    39601 tcgtcgttgt attttggata gattctgtaa tcgagttgac ttgggtgaag gttccgattc
    39661 ccaagagagc aaccaatact cctgctactg caaacaaaac agcaagtggt cgccactttt
    39721 ctcccatccc tagaaggata tagtgcatgg gacctcccgc tactgcacca tggtcgtcct
    39781 tggtgcggta tttgatggcc aagagtcctt ccgcatactt ggtagccatt ccaaagaaag
    39841 ccgccatcca catccaaaat agagctcctg gtccaccaac cttgatagcc gtcgcaactc
    39901 ctatgatatt tcctgttcca acagttgatg ccaaggctgt acacagagct gcaaaactgg
    39961 atacatcacc atgtccctta tcctggataa aaataagctg aaaggccttg ggcagacgca
    40021 aaacctgcaa gagtcctagc cgcatggtta ggtaaatccc tgttccgacc aataaaatca
    40081 agaggggcgg tccccaagca aaagcatcga ttgatttaag caattctaac attttcttct
    40141 cctatcgttt caaccccaaa agaaagagca catgcaagat acatgtactc tggaatgctt
    40201 agataaatgc taaaaagcgg tctatcctag ctctgtcctt ttacctgaga gtttgagcag
    40261 ttgcctgcct tgccccttcg gtgcctttac ggtctctcca gagttccgtc catttacagt
    40321 catggaaaat caaacgattc cccacttcta ttaaacttca ttcggtgttg gtatttaatt
    40381 gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg tttattagta aaaattagtt
    40441 caacagtttt tactttataa agtccagaat actgctatcc tttaaaagtg acaatagtcg
    40501 caccactgcc tccagcattt tgtggggcat agccgaaact cttgacatgt ttgtttcttt
    40561 gcaagtattt ggtaactcct tcacggatga ctcctgttcc gataccatgg atgatatcaa
    40621 cttgagccat attgttaagc aaggcttggt cgatgaaggt atctagctca ttcatggctt
    40681 cttcatagcg cttgcctcga agatccagtc tagcttgagg tcctcgccca gaagttcgtt
    40741 tcacaacatt gacctgtttc ttcttgactg gtttttcttg ctgggcttga acaagatcaa
    40801 actctttctc ttccaaggtc atcttaatca agccaatttg ggcttcccag cggccgtcct
    40861 tgagttgact ggtcaaggta ccacgctgac cataactgag aaccacgata tcatctccca
    40921 cctttggagc tcgttttttc ttggcctttt gaaggacctt gtttttagac aagtccactt
    40981 tttcaggagc caattttttc aacttggcct tggcttcaat gatttcgtgg ggcttgagtt
    41041 gggatttact gtggagattt ttgagaatct ggtcactttc acttagggcc atatccacaa
    41101 tctcagcagc ctgttcacgc gccttgttaa gctcggtttc cttttcacga ttaagctcgt
    41161 tgtagagttt ttttagcgca cggttcatct tgagattttc ttgctccacc tcacggatat
    41221 tgtccaagcg tttgcggctt tccagcgtct gctcttctaa ttgctcaatg atacgattga
    41281 cgtcattgtc ctgatcgatc tgctgactgg catctcctac gataacttca gataggccta
    41341 gacgtttggc aatttcaaag gcattacttc ggccaggaac accctgcata aagcgatagg
    41401 tcgggcgaag agttgcagta tcaaactcca tactggcatt ttgcacaaag gctgtctcaa
    41461 taccgtaggc cttgagttct ggatagtggg tcgtcgccat ggtcttgatt tgacgcaggc
    41521 gaaggtcctc cagaatagcc atggcaaggg ctgctccctc ttggggatca gtaccagccc
    41581 ccaactcatc caaaagtaag agtgaatgtt ggttgacctt gccaagaata tccacgatat
    41641 tggtcatatg gctagagaag gtagacaagc tctgctcaat agactgctca tctccaatat
    41701 cagcaaagat ttcttcaaaa ataccaacac gacttccctt gtctgctaaa atcggcaatc
    41761 ctgactgggc catgacctgt gtcaagccca gagttttaag catgatggtc ttcccacctg
    41821 tattgggacc tgtaatgaca atagctgtta aatcttgacc aaaatagaca tcatttgcga
    41881 cggcattttt gaccaaagga tggcagacat ggagcagttg aatctcttga ttttctgaca
    41941 gctgaggcac gactgcttgt ctttcttgaa taaatcgaac cttggcacga atcaagtcca
    42001 gatgaccgat aatccaagcg tcattagcaa tctcagccgc atgagggcgg acacgctcag
    42061 aaatttcttg gagaatgcga agcatttcat agcgctcatc tgctcgcaga ctagcaattt
    42121 cttcgctcag tttgactacc tcacgtggtt cgatatagac ggtgtttcca ctagcagaaa
    42181 tatcatgaac gacacctgca atcttattgc ggtaggtgtt tttgactggt aaaacctgac
    42241 ggccatttct gctagcaaca attccttccg tcaacatctg ccctttttgc ttgagcaagt
    42301 cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat ttttcgacgg attcgcgcca
    42361 attcttcact ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga agatttcctt
    42421 gtaattgcgg aaaatcatgt aatttctcaa accaaagggc taattcttcc aagctgacat
    42481 tttccagatt ggcgtaaaaa ctttgaagtt ctcggctggc aagaagcacg cgtttcaaga
    42541 gtaggaactc ctcgatattg agatccgctc ccatctccaa cctcttgcag actcctgcaa
    42601 tttccttagt tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc tgcatttctt
    42661 tcatctcagc aaaagcctgt ttgattttat ctgctttggc agtcggagcc agctgtctca
    42721 attgctccaa gccctgctcg gtcaacaaat gaggctcaaa caaggccttg accttatcga
    42781 actctaatgt ttctaatatt ttcttattca tctttatttc cttgtctttg aatgtctagg
    42841 tgtggtagct ttttacattc tgatagattc gagtcaaatc tgtaaacaaa gggctaggaa
    42901 aactcctgcc ctttttatcc gattaaattt gtcacccaga tttgtttgag ccaactggtt
    42961 gttatcggta tgctctggat gatgtgtttt gcgacgatac tcttttcaag aggattttgt
    43021 ataactgcca tagggatggt cgccaagatt gtcaaggcca tttgcaagac aaataaggtc
    43081 accaacatgg acaagatacc tgctgaaact tggaacaact taccacccag ttttttgcta
    43141 ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc tatagacaat cccaaataca
    43201 agcaagtagc cgatacctgc ataaaagacc ttatccagct gaaagagttg atccgatggg
    43261 aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag ggagcaataa atggaattgc
    43321 tctccaagcc ccttataaaa ctggccagcc ataaaagccg atgccatggc tgaaatcagg
    43381 taataaacct gtaagagcag gcctctccga tagccgatat aaaatcccca aaccaagacc
    43441 aatagaagaa ggaatgaaat cataaggaat cctcaatctt gctctgttct tgcttacaag
    43501 tcacaagctt gtgacggagt tcttctagct cttgctcctt atcgtcaaat tcaatctcac
    43561 ggctgagctg agttgataaa cagttgactg ccaacaaaag agcgattgtt tcatcatctg
    43621 cgctaggcat ttgttcttta attgcttggt atttttctgt cgcaacctta gcgatttcct
    43681 ccataaaaag gttatcatgt tcgcttgtca aggttaacgt ttttttcccg aatgtaaatt
    43741 tgaatcgatt tagatttgcc ataaaattca cctcacgata ttataccaaa attcgctaat
    43801 tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa tagaaactat ggcaagtatc
    43861 acactcacac caagcgaaaa ggatattcag gcttttcttg aacactatca aaccagtctg
    43921 gctcctagca agaatcccta tatccgctac tttttgaaac tacctcaagc aacggtttct
    43981 atctatactt ctggaaaaat cttgcttcag ggtgaagggg ctgaaaaata cgccagtttc
    44041 tttggctatc aagctgtaga gcaaaccagc ggacaaaatc ttcctttaat tgggacagat
    44101 gaggtgggaa atggttccta ctttggtggg cttgcagttg tggctgcctt tgtcacacct
    44161 gaccagcacg actttttacg aaaactcggt gtgggggatt ctaagactct gaccgaccaa
    44221 aagatccgtc agattgctcc tattctcaag gaaaaaattc agcaccaggc actccttctc
    44281 tcacccagca agtacaacga ggtcatcgga gaccgctaca atgctgtttc ggttaaggtt
    44341 gccctccata atcaggctat ctatctcctc cttcaaaaag gtgttcagcc tgagaaaatt
    44401 gtgattgatg cctttaccag tgctaaaaat tatgacaagt acttggcaca agaggccaat
    44461 cgtttcagca atcctatcag cttagaagaa aaggctgagg gcaaatactt ggctgtcgca
    44521 gtttcttctg tcattgcgcg tgatctcttt ctggaaaatc ttgaaaatct gggacgagaa
    44581 ctgggttatc agctcccaag tggagctgga acagcttctg acaaggtggc tagccagatt
    44641 ttgcaagcct atggtatgca gggactcagc ttctgcgcca aattgcactt taaaaacact
    44701 gaaaaagcga aaaaacgctt agaaaggtaa gttatgaatt catttaaaaa tttcttaaaa
    44761 gagtggggat tgttcctcct aattctgtca ttactagctt taagtcgtat ctttttttgg
    44821 agcaatgttc gcgtagaagg acattccatg gatccgaccc tagcggatgg cgaaattctc
    44881 ttcgttgtaa aacaccttcc tattgaccgt tttgatatcg tggtggccca tgaggaagat
    44941 ggcaataagg acatcgtcaa gcgcgtgatt ggaatgcctg gcgacaccat tcgttacgaa
    45001 aatgataaac tctacatcaa tgacaaagaa acggacgagc cttatctagc agactatatc
    45061 aaacgcttca aggatgacaa actccaaagc acttactcag gcaagggctt tgaaggaaat
    45121 aaaggaactt tctttagaag tatcgctcaa aaagcccaag ccttcacagt tgatgtcaac
    45181 tacaacacca actttagctt tactgttcca gaaggagaat accttctcct cggagatgac
    45241 cgcttggttt cgagcgacag ccgccacgta ggtaccttca aagcaaaaga tatcacaggg
    45301 gaagctaaat tccgcttctg gccaatcacc cgtatcggaa cattttaaga aacctaagag
    45361 gccgagaatc accaatctca gcctcttctt ctatcgtgag aagtgattgt ttattgacaa
    45421 atactcaatg aaaatcaaag aacaaactag gaagctagcc gtaggctgct taaaacagtg
    45481 ttttgaggtt gcagatggaa gctgacgtgg tttgaagata ttttcgaaga gtataaaata
    45541 aaaacaatcc caactctcac ctattcatgc aaaggaattt tatggaagtt tatttttcag
    45601 gaaccattga acggattatt tttgaaaatc ccagcaattt ttatcgcatc ctcctcctag
    45661 aaatcgacga tacggacgca gaggattttg atgactttga aatcattgtc acaggaacca
    45721 tggctgatgt aattgagggc gaagactata ctttttgggg gcaaattgtc cagcactcca
    45781 agtatggaga acaactgcaa atcagtcgtt atgatcgcgc aaaaccaact agtaagggct
    45841 tggtcaagta cttttcaagt agccatttca aggggattgg tctcaagaca gctcagaaaa
    45901 tcgtggatac ctatggcgaa aataccattg acgaaatttt gcaacaccca gaaaagttag
    45961 aaggcatcgc aggactctct gccaaaaatc gcgaggcttt cgtctccact ctccgtctca
    46021 actacggtac ggagatggtt ttggccaaac tagccaacta cggcattccc aacaaactag
    46081 cctttcagat tcaagacttt tacaaggaag aaacccttga tgtggttgaa aattatccct
    46141 accaactggt tgaggatatc aagggtttgg gctttaccat tgctgaccaa ctagctgagg
    46201 aactaggcat cgaaagtcag gctcctgaac gcttccgcgc cggtctagtt cacagtcttt
    46261 ttcaggcctg tatggaaaca ggagacacct atgttgaagc acgggatttg ctggaacaaa
    46321 cccttactct ccttgagtct tcccgtcccg tggaactaga ccccagccaa gttgcccaag
    46381 agctctccta cctgatcgaa gaagacaagg ttcagcagat tgataccaag atctttgaca
    46441 acagcctctt tttcgctgag gaaggcatcc gcagtcactt ggttcgtatc cttgaaaaag
    46501 gaaaacagaa gagtcatgat ttagaaacca ttcaaaaaca tatcactact atcgaggaag
    46561 agctgggaat tgagtatgat aacattcaaa aacaggctat ctgtgacgct atccagaaca
    46621 aggtctttat cctgacaggt gggcctggta ctggtaagac aactgttatc aatggaatca
    46681 tcgctgttta tgccctttta gaaggacttg acttcaggaa gaaaaacaat ctgcccattc
    46741 ttcttgctgc tccaactgga cgagccgctc gccgcatgaa tgaattgaca ggtttgccta
    46801 gcgcgaccat acaccgccac ttgggaatga caggtgacga tgataccagt catctggaag
    46861 attacctaga tgctgacttt atcatcgtgg atgaattctc tatggtggat acttggctgg
    46921 ccaatcaact cttctccaat atctcttcta acagtaagat cctcatcgtg ggtgacagtg
    46981 atcagctacc ttctgtcagt cctggacagg ttctagcgga tctgcttcat attcctttga
    47041 ttcctcagac tcgcttggaa aaaatttatc gacaaagcga agaatcaacc atcgtcaccc
    47101 tagctagtca gattcgacag ggcatcttgc cagctgattt cacccaaaaa aaagctgacc
    47161 gttcctactt tgaaattgct agtggccata ttcctgccac tattgaaaaa atcttaggtg
    47221 ccgccctcag aaatagtatt cctgcccgtg atatccaagt tctggctcct atgtaccgag
    47281 ggacggcagg gattgatgct atcaatcagc tcatgcaaga cctgctcaat cccccacaaa
    47341 aagatcaact cagttttgaa gctcctcagt gccactatcg taagggagac aaggtcattc
    47401 atttggttaa cgatgctgaa atcaatgtct ttaatgggga tttaggagct atcacagacc
    47461 tgattcctgg taaatacacc gaatcgaaac aagacgagat tgtcattgat tttgatggta
    47521 atgaagtctc ttacccccgt aacgaatggt acaagattcg cttggcctat gccatgagta
    47581 ttcataagtc tcagggaagt gagttcccag ttgtcatcct accgattact agtgctagcc
    47641 gacgtatgct ggagcgaaat ctcatctaca cagccattac acgtgccaaa agcaaactca
    47701 tcttactagg cgaattacaa gccttcgact atgctaccca acacatcgga actgcccgaa
    47761 aaacctatct gattgaacgc ttcagtgatc tactggagaa tgttgaagaa aagcaacaag
    47821 ctgtctctga aacagtcaca tcaagtgcct ctgaacaatc ctacatccta accgaagaaa
    47881 actgggacag cattccagcc atgattggga ttacagacac agacctcaaa gagatttttg
    47941 gaaaatagtg catcagaaaa accaccaatt caggtgggtt ttctgtttat taagattatt
    48001 ttactgttgc tgtgcttgtg atcaattcaa cagctttttt gatagtgata tcatgtttca
    48061 acatgtcagc tgaaagcaag ttttgaactt gtgcaacttc catgttgtag tctgctgcca
    48121 attgctcaac ttctttttgg atttcttctt ctgaagcatc aaatccttca gctttggcaa
    48181 ctgcttcgat aacaaggtta gtcttagtac gtgactcagc ttctgcttgg tattggttgt
    48241 gaaggtcttc ttgagtagtt ccagtgattt ggaagtacat gtcagggttg atcccttgac
    48301 gttgcaaatt cccaaggaat tcatttactg aacggtgaac ttcttcatgg atcatttctt
    48361 ctggaagttc tacgatttca gcattttcta cagctgtatc aattgctgca ccttcaactg
    48421 catctttgta agcttcttct ttagcagcag ccaattcttt gcggtatttt tctttcaagt
    48481 cagcaagtgt ttcaacttct tcatcaatgt cttttgcaag ttcatcgtca agagctggaa
    48541 cttctttagc ttttacttcg tggatagttg tcacgaattt agcttcttta cctgcaaggt
    48601 cttctgcttg gtagtcttct gggaatgtta cgataacatc aacggtttcg ccagctgagt
    48661 gacctaccaa ttggtcttcg aaaccaggga tgaattgacc tgaaccaagt ccaagtgaga
    48721 agttttcacc ttttccaccg tcaaattcaa caccgtcgat agaaccaacg aagtcgatca
    48781 caacagtgtc gccgttttca gcagcagctt ccttgataac caattcagcc aggttgttgc
    48841 gttcgcgttc gatacgctct tcgacatcag cgtcagttac ttctttttct acatcaactg
    48901 atacttcaag gtttttgtag tcacccaatt ttacttcagg ttttgtaacg acttcagcag
    48961 tgataaccca gtcttgacct ttttccattg aagttacgtc aatttttggt tgggcaacca
    49021 cttcaagacc agcttctttt acagctgctt cataagcgtt tggcaaaaga gcgttcataa
    49081 cgtcttggta aagtgattct tcaccaaatt tttggtcgaa gataggacgt ggaaggtgac
    49141 ctttacggaa acctggaaca ttaagagatt tcttcactga cttgaagaca cggtccaatt
    49201 ctggtttgat ttggtcttga gagatagtga aagtcaagac accacggttt gtttctttgt
    49261 tttcaaatga tacagacatt ctgtcatttc tccttaaaat tttttaaata cagtctatta
    49321 taacattttc tataaataaa atctagacta atgcagccaa ttatagacaa caagcctttt
    49381 tcctaactaa aacactcata aagtatagac aattttagac tactttggat atcttttggt
    49441 tagtcatttt ccaaaactaa tttatctaat ttttcagtta tatagtagat tgaaactaga
    49501 atagtacacc tctacttcta aaacattttt agaaatcgat ttgactgtcc tgatcgattt
    49561 gtcctgttct tgtttcattt tactatatag atcacattcg aaagaattcg ttccaaaatt
    49621 gcttggttcg ttcttctctt ggacgactaa agaattgatg ggcattattt ttttcaacaa
    49681 ttttcccact gtccataaaa ataacatgat gggctacatc tctagcaaaa cctatctcat
    49741 aaagctgatc aaaaactcaa tctgaggaga aaatccaata agactttcca taataaagga
    49801 catcctatca agatttttga acacccgata ggctgccttt ttccgatttt gaagactttt
    49861 tgtccagctt cttttacctt ataaataaca acaaaaatca aagacaagct agaaagatta
    49921 ccgcagataa ctcaaacagt gttttgaggt tgcagataag actgacggag tcagctcaaa
    49981 gcactgcttt gaggttgtag atagaactga cgaagtcagc tcaaaatact gttttgaggt
    50041 tgcagatgga tgctaacctg atttgaagag attttcgaaa aagattaaat atactctaca
    50101 atttgctcaa tcaattcttg gtcgtctaaa cctgtaactt gtataacaac atctttgact
    50161 gattgtttag ccaacaattc acctaatcga atactttctt catcatttac atcgcgatag
    50221 tcaaaggcat agccaactgt tttaagtagg tttttatatg acaaactgag ttctttcaat
    50281 tcacgtatcg gccggatgaa tcgttcatta tagcctaatt ttcggattgg agtacgagct
    50341 acgcgactaa cctcgtccac tatgaaaggg ttttcgaatc gttctataat gactttgtga
    50401 taattctcca attctttttt atcaaagttc catttggcaa tcaagagact ccgaatttca
    50461 gctaatacag attcaatccg agatttgata ttaggatttt gaagagcttc caaaattgtc
    50521 ttggcaccat aatgcgcacc aatgtaagct gaagttgcat gtccagaatt gactgaaaaa
    50581 agttttcgct caataaaggg ttctaaatct tcttcataat gcacatcttc tagacgtaaa
    50641 tctggatttt taagacgctt ggtttccacg acccattcat taaagggctc gaccataaca
    50701 aaaagggaat cttcgtgact ttgtgttgga acaatcctgt ctactgcagc atttggaaaa
    50761 cctatgtagt tatcagcaaa tgtcaaacct tccggactta aatatttctt gacttcttga
    50821 taaagaaatt gagacccgcc aatcatattt tcacaggcca taacatccaa tgcctgtgta
    50881 tttcctgcaa ctcggcgagc ttcgattcct ttggctagaa gttcagcgat aaaagggagt
    50941 atattaggtc cgattgcagt agtaataata tccgtctttt gaatcgcttc aatgacttgc
    51001 tcaggatgtt ctttgctatt aattccagcc acattagtta cttctatacg agactgtcct
    51061 ttctgtgcaa tttcaatttc atacttgccc ttttcattta gagcatgaat tatctgatta
    51121 ttgacatcca caaaatcaat atggaaatca tttttaaata gaatttcacc tataaaacca
    51181 cgaccgatat taccggcacc aaaatgaaca gaatgtttca ttcaatttct ccttttccta
    51241 tttgagggac atatatacta gatgacaaat gacgaaattc aattattcaa cagcatcaaa
    51301 taagcgcaat acttcctctt ttgactgagc atctgctagt ttaagaacat tatctacatc
    51361 tgcacagaag atagaaattt tctgaataat ttctaagtgt tcattaccaa taccagcaat
    51421 accaaaaaga accgttgcca cttgagggtt agatacattc ccaaaatcaa cccctctagg
    51481 gacttgaacg actgtaatac cagacttgag gacatcattt tttgctgcat ctgttccatg
    51541 cggtatggcg ataaagttac ccatgtaaac agatagctct ttatctcgct caatcatggc
    51601 ttcaatatag tcttcattaa catatccacc ctcataaaga acttgcccac aataacaaat
    51661 agcttcctcc ttgttagaaa attgtttatt aagcttaatc aaatgttttt caagtttcat
    51721 attagttctc caatttctta attttttcgt taaaaatagt atttagcatc tgataaataa
    51781 tggattgatt tcccgtcttg taaatctctg tataaagatg attttcaata atcgactgac
    51841 tgatagctgt cattaaatct ctcgcttcct cgctagcttc tttagacatt agcattagca
    51901 gacacctttt gacctcttct tcctctcgtt tcattgacaa tgcggagata ggtagtttga
    51961 gttcaaacat agtaaaacta tttgttgtta ctttgctaga ctgactatgt aaaagcacca
    52021 gaccagtatt aggaatagcc ataggactat tctggaagtg agataacaat tttcttgtta
    52081 ggtaatctct gtcactcaca ttcttctgat attggatgat ttgttctacc gtgtgctcaa
    52141 atgattgatt attctccaat tgaaccaact cgaattgact caaaagctga ctactagata
    52201 ttaaataatc ttgcaagtca taacttttct ctggagcgat agcatcacgc gcgacaattg
    52261 tacgatgtgc ctgtacatac tgaagtcgtt cctgtaattc aagcaattct ttgacggttg
    52321 gaaaactaga aattacatcg atttcctgat tagtcagcgg cttggtagat aaaatataat
    52381 catactgact gagatcaata ctgtggtaat ctactagaga ctgaatatct atcaactcta
    52441 caaaaggagc aacactctta attttactga ctaataaatc tctagtgacc cgacgttcat
    52501 ccgttaaaag caaaacacgg actggataaa tctctggact acggcctaag ctagagataa
    52561 aatgtagggc aatcatgcca tactcatact ctgtatgaag atatttcgga aaaatatcat
    52621 tcactaaaag actgatgact gtataaagaa atttattcct ttcaactaaa atctggacag
    52681 attctggcaa attttcaccc tgaaaaagga tagggacgcc taaactgagc cgaatatgat
    52741 ggaaaagaaa attgaataaa accttgtcct taaaaaagtc aatcttggta tacatggaaa
    52801 ccgtatcaat cagatttgaa atattgtaga aaaattcacc atcaaatttc tccgtaaaga
    52861 gcggattgtc ctgacgttta atgattaatt catccaagat gctcgcaaaa tagataattt
    52921 cctgaatact ataaaattgt gcagtctgct tagagtaagt ttgaaaaatt ttttgagaaa
    52981 tttccaaagc ctgcttacta gtattaggtg aattttcaat gttttgctcc tgacctataa
    53041 gagataacaa gatcgcaaaa aacatcttca tcctagcatc catatctgga aaacctgaca
    53101 gttgcttatt aacaatctga ctggccagcc tagttctatc tgcttctaaa atatcaaagc
    53161 tcccaaaatt accggttgaa aaatctgcta ctgagataca gtttgtcagt aaaatagcca
    53221 aaaatcttct cttaccaact gaatcaccag aaatccgata acctttttgt cgttcaattt
    53281 tcagatcaaa gtctaaaaga cgcttatcaa tatctgaaat atcctgaata atagttacat
    53341 tactgacttt cgtgcactct tgcaatgctt cattggtgac aaaaccgctc tcagtcagaa
    53401 ggcgataggt aatcaactct tgtctttctt ggggactata ctcaactaac acttcaagtt
    53461 ctgtcggcaa atcatccaac tctccagtca aaatatagta tttcccatgc ttcattattt
    53521 cgattccata ttgctccatg ctatctgtca aatctgataa agttcgataa attgttctag
    53581 atgaaacctg taagatttca gtcatatctt gcattgaaag cttccctaca tgtaggaaag
    53641 ccttcaataa ttgttcttct cgtttggtta atagcattcg taatttagaa acctctagtt
    53701 ctatttgtac attctagcag ccattttgtc atattctggt gttgttacta aactatccac
    53761 aataagaaat tgagaattcg gtgctgcttg ctgcacttct gcctgtaaag aaatagttgt
    53821 tacaatcatt atgtttttag aattaaattc acctaattct gaaattttgg cagtagaaac
    53881 tggaatacga atattcttgt ttctaaagat agcccgaatc gtttcacagc ccatagttgc
    53941 agttccctgt gctttaccat aagcaactac tacagcatca atatggttaa ggtcaatttc
    54001 ctgactatct actggtgctg aagttggtat atctccttca atttctgcta ttggagaagc
    54061 tcctgttaat gaagctacaa tttcatcata acgaggggac gctaagaaat tatcaacaga
    54121 aacatgaata gcacttggac tcttgtcttt agctcttggt gtcagttctt cctgagtaac
    54181 aattaatgtt tttggtgtat caagcaaatt tgagattgcc tgattagata ctggaatctc
    54241 tagacctgct tttttaacct tatctcgaag aatactagct cccatagcag agcttcccat
    54301 accagcatcg caggcgaaaa tgattttttc cactgagtct gtcgaaacaa ctgcatcaac
    54361 agaagttgat actaactgac ctttagactg agccttagct gcttgggtag ccgcctgagc
    54421 agcttcgagc gaatcctcag ttgacttgtc tgcatgaaga ataagggctg ctacaaggaa
    54481 agaaacaact gctgctacta aaacacctag aagaacattt agatggggcc aaacaccttt
    54541 tggcgccgta gccataatcg caataataga acctggtgaa gctggagatt taagaccagc
    54601 gtctaagagt tgaaaagtaa aagttccaga gatacctcct gccatagcag ctaaaaatag
    54661 agtaggcttc atcataacat aaggaaagta aatttcatga atccctccga agaaatgaat
    54721 aaccattgcc ccccaagaag aagatttagc agaaccttta ccgaatacag cataagctaa
    54781 tagaattccc aggcctggtc caggattagc ttccaatagg aagagaattg acttaccagc
    54841 ttgagctacc tgttctactc ccagaggagt aaaaatgcca tgattgaggg cattattgag
    54901 gaaaaggact ttagccggtt cgatgataat attagccata ggaaggaggc gagcattgac
    54961 aatagcctca acaccattcc caacagctcc agtaagagtc gatacgactg gaccgattgc
    55021 gtagaaagcc aaaagcaata atgcaaaacc aacgagacca gctgagaagt tattaactaa
    55081 catttcaaat ccgggacgaa ttttttcttg gaacttctca tcaaatttct tgatagtcca
    55141 tcctcccagt gggcccatta ccatagctcc gataaacata ggaacactag aacctgtgat
    55201 tgcaccaaca gtagcaatag ctcctacaac ggcaccacgt tggccatgga tcatatatcc
    55261 acctgtgtaa ccaatcagga ttggcaataa atacgttaac ataggaccaa caacagtagc
    55321 taactgttca tttggcagat agccatcagc gataaagagg gcagtcaata ctccccaagc
    55381 aataaatgct ccaatattgg gcataaccat atttgaaagc gatgtcccta gtttttgaac
    55441 cctgactttc aatgatactt tttcttccat tagatcatcc tccttttctt aaaactagta
    55501 tatacaaagt taaaaacctt taaaactaaa gttttgtcac agattttgtg tcaaaacatt
    55561 acttttgacg aggctgggca aaaaggctta aaaattataa aacgcatcat atcaggtgta
    55621 catgaactac accccaaaag ttagacagaa aaaatctaac ttttggggtg tttttattat
    55681 gaaactaact tatgatgata aagttcagat ctatgaactt agaaaacaag gatatagctt
    55741 agagaagctt tcaaataaat ttgggataag caattctaat attaggtaca tgattaaatt
    55801 gattgatcgt tacggaatag agttcgtcaa aaaaggaaaa aatcgttact attctcctga
    55861 tttaaaacaa gaaatgagta ataaagtctg acatgaaggc tggactaaag atagagtttc
    55921 tcttgaatac ggtctcccaa gtcgtacgat acttcttaac tggctagcac aatacaggaa
    55981 aaacgggtat actattgttg agaaaacaag agggagagta cctaaaatgg gacgtaagcc
    56041 aaaaacgaga cctgaagaga ggacagaatt agaacgtctt caagcagaaa atgagtacct
    56101 gagagcggag aatgccatcc taaaaaagtt aagagaactc cgattgaagg aggagaaaga
    56161 agaaagacag aaattgttca agaattaatg actgaatttt cgttagctct tcttctaaaa
    56221 gtcattaaac tagctcgttc gacctactac tatcacttga aacagctaga taaaccagat
    56281 aaggactaag agcttaaagc tgaaattcaa tccattttta tcgaacacaa gggaaattat
    56341 acttatcgcc gggttcattt agaactaaga aatcgtggtt atctggtaaa tcataaaaga
    56401 attcaaggct tgatgaaagt actcaattta caagctaaaa cgcgacagaa acgaaaatat
    56461 tcttctcata aaagacgttg gcaagaaggc agagaatctc attcaacgcc aatttgaagg
    56521 ctctaaaaca atggaaaagt gctacacaga tgtgacagaa tttgccattc cagcaagtac
    56581 tcaaaagctt tacttatcac cagttttaga tggctttaat agcgaaatta tcgcctataa
    56641 tctttcaact tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga
    56701 gaagcactac aagaatacga ttctccatag tgaccaaggc tggcaatacc aacacgattc
    56761 ttatcatcgg ttcctagaga gtaagggaat tcaagcatcc atgtcacgta agggaaacag
    56821 cccagacaat agtatgatgg agtccttctt tgggattctg aaatcggaaa tgttttacgg
    56881 ttatgagaag tcgtttcagt cgcttaagca attggaacaa gccattatag actatattga
    56941 ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagccctg tgcaatacag
    57001 aactaaatcc ttcggataaa ttaattgtct aactgtttga gggcagtaca gaaaaacctt
    57061 gatactatgc gttttttgat tgtgaagact tttatccacc tattatacaa agttaagtat
    57121 ccatcacagt ttacaattag ccttcattac ttaacccatt caccattata gtttaagtag
    57181 taaccaccta ctgtggtatt aacagctaaa gcacctgaat cataggcata gtaccagtta
    57241 ccattgactt ggaaccagcc tgttttcata tctccattac ttgcatttag atagtaccaa
    57301 gtcgaacctt cctgatacca accagttgcc atagctcctg atgaacggag atagtaccat
    57361 ttgttcccaa ggttttgcca accagttttc atatcgccat tttcagcatc taaatagtac
    57421 caagttgaac catcttgata ccagccagtt gccatagctc ctgatgaacg gagatagtac
    57481 catttattac caagatgttg ccaacctgtt tgcatgatgc cagttgctgg atctagatag
    57541 taccatggag ctgcttttag cttctcttca tcataggtaa gagggtaatc cttaacccaa
    57601 ccacgtgcta gctctccaac cgtcaatctg ttgatgcgag aatcaaagcc accatccttc
    57661 tgcaaataat accagtcccc atcatcataa acccaaccag tttttaaagt atgataacta
    57721 cgctgatctt caaaataata gactcgtttc tctgctgggc tatcatattc ttccccatga
    57781 tgtttgttgg tatttgtagc agtttttgct tctaacactt gcttgccaac aaattcttgt
    57841 agtaccccat cttgaccaaa gtaaaaccaa tctggtctaa aagcaatctc ttgtcttgga
    57901 gaaggaccaa tcgtaacccc cttgtgtgga gcaggtatat attgccagcc gacaaccatc
    57961 tctccggata aaggatcaaa ataatagtat ttcccatcta tcactctcca gtaggtttct
    58021 tttagatccc cctttttgta gtaggttcta ccattttctt ggacaaactg ccatccttca
    58081 gaatcatctg caaatactgt actggtccct agcaaaccga agaaaaatgt ggctagtgcg
    58141 acttgcatca tttttttcaa aagcttcatt ttatatatcc tccaacatta aatccactca
    58201 ccagatgaag cgaagttata aactttacca tcgatagttt ggctacctgt aaccattgct
    58261 ccatttgaat tgagataata ccattttcca tttacttttt gccaatctgt aagcatctta
    58321 ccggaactgt ctaaataata ccaagtatca tttatctcct gccaacccgt ttgtttatca
    58381 tgttgtctat aatggtacca actaccattt attttcttcc atccttcaag agagtaacct
    58441 ttaagaaccg aataaataaa tggcaaattt cgttcattta atttaactgc actgttaatt
    58501 tgattagctc catctcctaa agtatgcact cctactacac ggtgactagc atcataaact
    58561 gtagatccac tagacccctc taaagtatca acttggtaat ccaagaacat gccatcatca
    58621 cttaaaactt gttttttatc tgtatacatt tgatgaactt taaaattata tgatggatag
    58681 cctgtgatag tcacagttat tcctgtcaaa tttttttgac tagtaggaag acccaaagtc
    58741 cctaattttg caccaatggg ctcttctaga attaataaag ccaagtcata ttcccttgca
    58801 tccttagaat ttaaatttct aaattccttc aaataacgaa cttcctttac tttgatcttt
    58861 ccaaatggtt cttgacttgg actaacagcc ggaagaacat aaatatcatc cgcttctttc
    58921 ccatagtcat gtctgtagta gctgtgagcc gctgtaatta acacattatc tttaataaaa
    58981 ttcgcacttc ccctcccttc tacattcatt ccatcggcta ctccataata cttagataaa
    59041 accatagctg aagtcgaata cggatactgt aaagtattat caattttaat caaatcatca
    59101 ttaccgataa tacttctgat tgcttttggt agtatgaacc atatgttggt gaaatctcag
    59161 ataatgaaga atcattagat cctggacctt tttctagtgt ctcacttacc tcatattctt
    59221 cacccgtact agaaataaca ctcaaagcag atactgtcga taactggcta gccaataaag
    59281 tactcgcaat aattgaaata cccaattttt tataaacagt tttcttcatt attgtatcct
    59341 cctaatgtaa ttatagcgta ctattctaaa tttcttaatc tactatagaa tcaagaaatc
    59401 taccaccttc tttaaatacc ctccattatc acataaacag gtaaactttt caattaatga
    59461 ctgcgctttt caatcacgct agaggtactt acttgcttct ttgatactaa gttcagccat
    59521 tctttccttg tttttctcaa taaagcatgt tacccaagtg ggattcgttt tggagtagtc
    59581 tcgcagagtc cagccaatgg ctttattgat aaaaaattct gtttggttca agttatgaag
    59641 gagaatcttt tccattaatt gagtattggt cttctctttt cttaacaact ggttgtcaat
    59701 agcgacacgt ctcagccaga tattatctga taggctccat tttatactca atgaaaatca
    59761 aagagcaaac taggaagcta gccgcagatt gctcaaaaca ctgttttgag gttgcagata
    59821 gagctgacgt ggtttgaaga gattttcgaa gaatattaag attatttctt ctagttcagg
    59881 atgtttatac accaaactcc ctactactcg atctaggata tctaccgtgt cccaccagga
    59941 ttttgtcacg actaactgct ctagcttagg caaatcggtt tcctttagat aagactgcat
    60001 tgctttcaaa tagttagcag ccacatattg gtattttcta ggctcctttt cccagcaagt
    60061 gtctgcaaaa tcccaatcga taatctttgt ttttttcgct tctggaaaat atttttatag
    60121 agtttatttc tttcaaccta gaaaagaaaa ttgatggcac atataggctt ccatgggcct
    60181 tgctttttta gagtcttttg ctgcttctag ctcctcaagt aaatctgcta aactcatcta
    60241 aaactcctca tgccccacca aatggtgctg aaaggcatag acagccgcct gggtacgatc
    60301 gctaacttca agtttggcaa gaatgttgga cacgtgggtc ttgaccgtct tgagagagat
    60361 aaagaggtca tctgcgatgc gctgattttc gtagcccttg gcgatgagtt ggagaacatc
    60421 tcgctcacgc gcagtcaatt cttcatgaag ttccatatga ttgcggtggt attcaacctt
    60481 cttgctaacc tcttgctcaa tggccagctc gccagcagct accttactga cggcatgaag
    60541 caattcatct gcactagaag tcttgagcat atagcctttg gcaccagcat ctaagactgg
    60601 catgattttt tcattgtcca aataagaggt cacaatcaaa atcttggctt caggccattc
    60661 tttaaggatt gctaaggtcg cgtcaatccc attcatctca ggcatgacaa tatccatgac
    60721 aatgacatct ggacgcagtt ccaaggccaa gtcaatccct tgagacccgt tggacgcctc
    60781 acccacaact tctacatcgt cttggaggtc aaagtagctt ttcaagccca atcggaccat
    60841 ttcatggtca tctactagta aaattttcat ctttactcct ttatcattcc ttatctaaca
    60901 ggggaatacg gatatcaacc gccagccctt gcttgggagc tgtcaagagt tgaactgttc
    60961 cagccatatc ttcaacccgc tccttgatat ttcgcagtcc ataactcaag tcgtctaagc
    61021 tccctaactg gaaaccaatc ccattgtcca ccaccttcag ttgcaattca acatctgtct
    61081 gatagaggta gacatctagg caagatgcct gggcatggcg gagggtattg ctaatcaact
    61141 cttgcaggat acggaagata tgctcctcga ttttcttagg caatttcgtc atattctgct
    61201 tgagactaac cctaagatca ctcttgtcct caagctcttt taagagaatc tgaatccctt
    61261 ctatcaagct cttctgctcc agttcaactg gtcgcaaatg caagagcaaa acccgcaaat
    61321 ccttctgggc tgtttctaaa atagctgtga cactctgcaa ctggatctgc atcttttctc
    61381 tatccaattt caaagcctgc tgactgatac ccgataaaat catgtgggcc gcaaacaact
    61441 cctgactgac tgtatcgtgc aaatcccgag caattcgctt ccgttccttc tcgatgattt
    61501 cctcttcctg agcaaggctc tgattttcag ctttttgaag agcttctgtc aaaaggttaa
    61561 gtttacctga taaggacttg aaactggcat ccaaatctgg atctgcaacc tgaaccactt
    61621 cttgccctgc caataaacgc ttgagattag cctgcatttt tcttagagaa agctcttcga
    61681 tccctcgcca aaacagggct aagagacagg ttatggacat gctgaaaacc aacaataaaa
    61741 agacaaattt ttctgttttt tcgacatcgt gcaaaaagat agaccagtca aaatcaagta
    61801 tttccagcaa gctgtgggag aaaaaaaaga caaacaggaa ggaggtgaga gcaataatga
    61861 cataggcttg ttttttcatc ctctaaccac ctccacatca ccaatcatag tggtcaagaa
    61921 aatcttgaca ctcttgttac tcttgagata gtcttttgtt tcttgatgat agtgttcatt
    61981 gcggagggct cgcttgggct ggttgaaaaa agtcaaatcc ccatagagac agttaacgct
    62041 gagactgact tccacatcta caggtacgat gattttggtc gttcctacca tctttctgag
    62101 gataatgaca ttgtcatgat tggttaagat gaccctctcc agatgaatag tgtccttgcc
    62161 catgaagcga aagagattga tatcatcgaa ttggcaagtc tggtagcttg aaaaatgatg
    62221 aagatttcca aaccaacgat ttttctcctt cttaaccgtc acgacctctt caaaaaccaa
    62281 attggtctgc tctttttcct ggttcatcat cgggtaaaga agaaagaggc tatagataac
    62341 cgcaacaaaa atagctagaa tcacaaaagg attgagcata acgatgaaaa agaagagaat
    62401 ggttgccgct actaaaagaa gattatttcc ctctttacca gtgtagtagc gaatcaaaag
    62461 caaaaagagg aatagtatca gcagaaaacg cgaaaaatgc tctgatacca tcaaaatcag
    62521 agctcctgtc agaagacagg cttcgataaa taaaaagatt ttaaattttc tcataggttc
    62581 atcctctccc ttctatttta tcacaattca aaaaagtcac ctcagtctga ggatggaaaa
    62641 aaggcgctgg ttacgccttt ttcatctgat cctttgcttc ttttaatttt ccataaagaa
    62701 gatagtctac tttttgtaga tctgctatgg tggcacagtt aagggaacac ataatcaagc
    62761 gtaggtctgc tttccagcct tggacaatgc caatcacttc ttcaactgtg taggtttcaa
    62821 ccaattccag aacggttcgt gacaatccca cagacttagc accaaaaacc aagcacttaa
    62881 tcatatccag cggattccga acccctccac taaccaagag ttcgacctta tctttccatt
    62941 cttgggcatt gagaagggcc tgcatggtag actgacccca ttgattgagg taatcacgct
    63001 ggccactacg acggttttcg atataggcaa agctggtgcc accacgaccc gataggtcca
    63061 ctgtacgaac accgaattca taggctcttt cgattgtctt ggcatccatt ccaaagccca
    63121 cttccttgag gacaatagga acgggaattt gctcgctata atctgctaga tgcgattgcc
    63181 agcttctaaa cttcctttct ccctcgggca tgagtaattc ctgcatgaca ttgacatgca
    63241 cttgcaatag aacaggattc atctcttcta cagtctgaag tcctaactcg acaggcttgt
    63301 ccaatccaat attggttcca aggaggagat tgggatgact agacttgaca gaaaaagaat
    63361 catccgttgg atttttgagg gctgcgctat aagaacccgt tacaaataaa ataccacagg
    63421 attccgccac ctgagccagc ttttgattga tttctcttcc cttattactt ccaccagtca
    63481 tggcattgat ataaaaagga aagtcccact ttcgaccagc aaactctgtc gaaagatcga
    63541 tttcatccag attgtaaaga ggcaaggaag aatgaatcag ctccacctca tcaaagctat
    63601 tataggaact tttctgctca agggcataga ggatatgctc gtccttacga tttgtcgtca
    63661 tgtcctatcc tttcttgata taagagctca atccccagat cggcccaacg attttttaag
    63721 gttttggttg attgcgcatc aaaactcagg gcgatgccac agtcaccacc accagcacca
    63781 ctactcttgg caacggcctg caaatcttga ctggcttctt tcaactgtct aagcaaaggc
    63841 gtgtaaatat ctgtactcaa gccttctaaa agcttgctgg ctacttctac ttgctcgata
    63901 atcttttctg atttcccctg ttccaaggct tcctcaaaag aaaccaccgt ttcttttgag
    63961 gaagttaaaa aattttgatt gatattttgc ttgatttgct ggaccatgtg actcgataca
    64021 gccacttcct tggtccatcc cactaagaaa tcacattcta aagttggttt cacttgtgaa
    64081 attgaaaagc cccaatcacg ctccagaact gtcgccaagt tttcttcttc taaccaagca
    64141 gccaccttct ggcgatcaaa tgactggtag agaaccaaat cctctgccac aatacaggca
    64201 aggtcgccca tggaaccatt gtctcctcgc ttgagcaaga cagcgctagt cagcttgaac
    64261 aagagctcct gatcaacaga aacatcatac agagccagta aagccttgac aaccaagaca
    64321 acgacgctgc cactagaacc tagaccaaac tttttccctt ctcgttccat tttgccacag
    64381 atttctagag aaaaaggtct taaattctga ccacgaacag cgaggaagtc tcccatcaaa
    64441 gcaatcgttt cttgaatcaa gctgtagtca ggattaggcc ttaagtccac tgcgaaatca
    64501 aacatatctg aatagatacg gtagctgtca gaaaaagcaa tctcagccct catatagatg
    64561 agaatatcct ttatcaaagc taactgccct ggctctaaaa tagcatattc acctgcccaa
    64621 tagagttttc cgcaagtttt aacagcaatc atcttgactc aaatcctttg tttttgacac
    64681 aatcaagcga taacgctgac cgaaaatttc tgacaaatac tccaagtctt tctcctgaca
    64741 gaagacctta acattgggac cagcatccat ggtaaagtag caggcctctc ctttctcacg
    64801 aagctggcga acaaagtcca tagcctcata agaggcatcc gtcagataag aaaaggctgg
    64861 actagcagtc tttgtcgtag catgcatagc cagggcattt ttctccgtta attctccaat
    64921 cttggcaaaa tcattttcct tgagataaat cagcatatcc tgatagtcct tctcagactg
    64981 acgaacccag tcgtcgaaag tcgtcgaggt ttccacacaa agtttcatcc cgtcacggct
    65041 agagattggt tttttcttgt cctctagcac caacataatc atagctagtt tcaagtctgt
    65101 ctctacaggg taaatttctc cactatcctt atcccaggct cctagtggtc cataaaaact
    65161 ccgagaagaa gagcctgagg caaatttggc ttcctgtgcc aactgacttc tatccaatcc
    65221 aagcttgaaa taagcattac aagccttgac cagggcggac aaaccactag aacttgagga
    65281 caggcccgct gccgtaggca tattgttttg agtatcgata cggacaaagc cctcaccagc
    65341 tggacgataa cggtcaataa tcttactcat cttggcatgc tcgacctcat tttgtagctg
    65401 accattgatg taaaattcgt cagctgttac attggctggt aaaggcgaca aggtcgtctc
    65461 tgtatacata ttttccaaag ttagagaaat actgctagta gcaggcacca tctctttttc
    65521 ttttttcttt ccccaatatt tgataatagc aatatttgcg taggaacgta ctgttacagg
    65581 ctctctatcc atgtctgaac agctcctttc tcttctaatc tttctgctag ttcttgtgcg
    65641 tgtgtcaaat tggttaccaa ggctatgata caacctccta gcccaccacc gctcatcttg
    65701 gcacccagag caccatggct aagagtcgtt tcaaccaaaa agtctgcctc agggctactg
    65761 actccaattt cttttaaatg taaatgcgct tgactgagga tttgtcccag tccttcagca
    65821 tctttttgtg aaatcgcaac ttctgcttgc tgggttaatt ctcccaaggc atgcaaaaac
    65881 ggtagggcat ccttgccctt attttgaacc acttggatgg cttcacgagt atgaccataa
    65941 acacccgtat cggcaatcac caaataggcg gataaatcca tctcaagttc tgtaaatcct
    66001 acgttcttga taaagcgaat aggttggtca ctgagacagg tcttagcatc caaaccacta
    66061 ggattcatat gagcaatcat ctcagctcga ttgaccaaga tttctagtac atcatgaggc
    66121 agatcagcct gatagtagtc aaataccgca cgaatggccg ctatgctgat agccgctgac
    66181 gaacccatcc cccgtttctc agggatagcc gagtcaatct cacaacgaac gcaggtttct
    66241 gtgatatcca aatactccag tgaagcataa accgccatgg acaaggtatc ctcctcataa
    66301 aggcgccaag gactctctgc aggaactacc ttacaggtca cctccacctc caaaagaggc
    66361 agggaaatgg caggataacc gtaaacgacc gcatgttccc ctattaaaat tatcttacta
    66421 tgtgcctgac cgacaccaac tttttttgtc attttttcct tttactagac gaaaaaacgt
    66481 cttatttttc atacaagtat taattctttc ctatctattt tattatattt tcacaaaaaa
    66541 agcgattgtt tccattcaca atcgcttctt tcattattga acccattcgc cattataatt
    66601 gacaaaatag ccatctacgg tcgtattcac tgccaaggca cctgagctat aagcgtagta
    66661 ccatctgcca ttgacctgga accaacctgt cgtcatagaa cgacgaaaga aactccatac
    66721 cattaagtaa agaggaaagt cgtgagggag catgcgccat tgacaacctg ttttagtgac
    66781 gtacaaagtc tcattaacaa gtactcgttt cggtcattta taggtgcggt gtttggagaa
    66841 atagggttca atcttagccc attcttgatc gtttaaatca gtatcatata ctttgcgtgt
    66901 cataactcta gtttaacatt ttttgtgaat acaggttcta aataatcgac cacgaaaatt
    66961 tcttaagtgg aaaacgcctt atgaagtatg ctacgggaaa gttatgcact taatttgaca
    67021 attcaagatg taaaaatata tactatagta gattgaaact agaatagtac acctctactt
    67081 ctaaaatatt gttagaaatc gatttgactg tcctgatcga tttatcctgt tattatctca
    67141 ttttactata atatttgata agttatccta aaagtattat tatgttgttg tgttatagat
    67201 tgattgaatc taactaaagg atcctattca attactagaa ctatcacata ctcaaggtca
    67261 gctcacagat gagcaactat tttggttaca atgtctacta aatttaagtc aaacaaataa
    67321 tttagtcaaa attaaaaaaa tagaggaaca taaatatgat tacaaaacag aatgtaatag
    67381 tgttctacaa tttttactag ataaaactgt aaattctgaa ggaaggatca cttcttcaac
    67441 agaatttgga aatttcgtaa gtaatttatc attccaacac ggaatagctg gactactgtt
    67501 tcctctaaat aaattgtacc ccccagaact ggattctaaa atactctcta tcatcaagaa
    67561 ggcagtgaca attagaacga cacacacata tgaatatcaa tactcactgc tatttggtga
    67621 tgcaggctat ctatggttac tcctacattt attttctatc agtaaaaatc aatactatct
    67681 acaattagca aacgtcaccg ctaaaaaatt aatagagaat tatgatactc tagaggaaat
    67741 agactttgca ttgggaaaat ctggtgtcct attatcatta ataaaatact atcaatttac
    67801 caatgacaat actcttaaaa ttttcatcca caatagtata ggggaaattt atcattattt
    67861 cctacaaaga gatacagcca aagaaagcat tttagactat agctttgctc atggatattg
    67921 tggaattgca tatgctttat ttgcctattc taaagtctta gaaccttcta tgttctataa
    67981 tgatctccat acattccata ctgaattaaa aaaattatta gaaaaagtta cttctaatac
    68041 tgaaaattta ggaaatttac aactttcttg gtgcaaagga atttccggaa taatcttata
    68101 tctttgtatg tacgattgtg acggaaacaa agatattatt agtaaatatc aagaatttgt
    68161 ttttaaccat catctaaaaa tgatgacagg atattgccac ggaataacta gcttactaca
    68221 aaccactgtc tacaatcaaa acaaattact gatgaaaaaa atccaacagg taattttagc
    68281 atgttctgaa cgagatgatc acggtttact tatgtttcaa ggagatagtg gtaaagcaga
    68341 tttgtttgac ttcggaatag gaagcatggg gtatattggt gtctattaaa taataaattc
    68401 ccattcgatg tgcagacata aggagaaaag tatgaaatta ttttggacaa acaacatata
    68461 tagacagttg ctgctaaaca gctgtttttc atcattcggc gacagtattt tctacctcgc
    68521 cattatcaat tatgtggctc agtacaattt cgctccgcta gcgattttac tgatttccat
    68581 ttcagagatg gttcccctac tatcgcaact ctttctcggg attctaggag attttcaaga
    68641 aaatagagtc aaacacgcac tctggattgc caaaatcaaa atcctgctct acgctatttt
    68701 gacagtattt ctcgtcttgt cgcccttttc attagtttca gtcattatga ttgtcatcat
    68761 caacctcatc tctgacacct tgagctacct gtctgcctac atgatgaacg ccctctacat
    68821 cagtgtaatt aaggacgacc tgcatgatgc catggggttc aggcagtctc tgatgagggt
    68881 tgtccgtatt gtcgccaatc tggctggcgc attccttatc aatgttataa gtattcaaac
    68941 tatttccctt atcaacactc tgacttttgt cattgccttt ttgggcctgt atgttattcg
    69001 acataccttg tatgaggttg aaaaaagaat tgaaatgtca catacagcac tgagttttaa
    69061 gaaatatttt caacatctta aacagtcgct ggctgtgctc ctgaggttaa aagataccgt
    69121 catactactg tttctgacga ccagtatgat tgccatcttg gatgtgtccc ctcggctgat
    69181 tgccctccgc ttcatccaac agacactagc acaactgagc attgggcaac tcctcgccct
    69241 gctctccatc atcatgtctt gtggagctat ccttggcaat atgaccagca gtaatctatt
    69301 taaaaatatc cgtttcacgc acctcttggt tttctgtgag atttccctat tgactctaat
    69361 aactagtatc ctttgtcaag cctatatcgt aattttcatg accagtttca tcagttctac
    69421 gattatcggc attctcagcc ctcgcctaca agcagctgtc tttgcccata tccccagtga
    69481 caagatgggg acggtgggct ctgctctgag cacagtggac attctcgccc cgtccctgct
    69541 ctccctatta gccctatcca tagcatcggg cgtttcggtg cagttagcat tgatattttt
    69601 gtatcttatt ttaattgctc ttatcttttg tcaatggtta gtcaagttca acactcataa
    69661 ctaacgaaaa agcatgtgta gatttcacat gcttttaatc tccccaatcg tcaggtcaag
    69721 tacaacaaag tcacttcttt gattaagcga gtgttctaat ataattataa gcgccctgtc
    69781 attaccgaac ccattcgcca ttatagttga cagaatagcc atctacggtc gtattcactg
    69841 ccaaagcacc tgagctataa gcatagtacc agttgccatt gacctggaac caacctgtct
    69901 tcatgtctcc attacctgca tttaggtagt accaagttga accatcttga taccaaccag
    69961 ttgccatagc tcctgatgaa cggagatagt accatttgtt cccaaggttt tgccaacctg
    70021 ttttcatatc gccatttggg tggtctaaat aataccaagt ggtaccttcc tgataccagc
    70081 cagtggccat tgctcctgag gaacggaggt agtaccactt attacctaga tattgccaac
    70141 ctgtttgcat aataccagtt gttggatcta ggtagtacca agtcgaatca tcgtttatcc
    70201 accccgcacg tctttcacca ccaaggtagt tttctccatt aatttccgtc ttagctagat
    70261 aataccagtt agactgatca taaagccaac ctgtctctaa agaatgattt tgattaaagt
    70321 aatagttcgt ataataacgc ttctcttctt tatcttctga atcttcacgt ttttccccgt
    70381 actttcttcc aacactgtct ttagttttaa tctctaatgt tttccaacca acaaactctt
    70441 gtagcactcc atttttatcg aagtagtacc actctgactt tggaaaacct tctaatctga
    70501 taccatttgg gtaaggacca attgtactac ctttagatgg aaacgggata tattgccagc
    70561 cgacaaccat ctctccagat agagaatcaa aataatagta cttaccatca atcactcgcc
    70621 agtaggtttc tttgaggtcc ccctttttgt agtaggttct tccgttttct tggacaaact
    70681 gccatccttc agaatcatct gcaaatactg tactggtccc tagcaaacca aagaaaaata
    70741 ctgtcagtcc aacttgcata gtttttttca aaattttcat ctatataccc tccaatatta
    70801 aatccactca ccagatgagg cgaaattata aactttacca tcgatagttt ggctacctgt
    70861 aaccattgct ccatttgaat tgagataata ccattttcca tttacttttg tccaacctat
    70921 tttcatatct ccattagaag gatctaaata gtaccaagtt gaaccatctt gataccagcc
    70981 agttaccata gctcctgatg aacggaggta gtaccacttg ttaccaaggt attgccatcc
    71041 tgttttcata tcaccatttt tattatctaa gtaataccat ttgcctcgta catatttcca
    71101 acctgttgcc atagaaccag aggagccaaa ataataccat tttccgttta ctttttgcca
    71161 atctgtaagc atcttacctg aagcatctag gtagtaccat ggagcaggtt tgcttctatc
    71221 aatgtcaata gtaacatgaa aatcttgagt ccaaccctta gcaacttcac caattggtag
    71281 tggattgtaa gaatcatcgc caaaatttcc tagcttattt aaataatacc aatgaccctc
    71341 ttcataaatc cagcctgtct ttacagcata attattatca aaataataag ttctcttttc
    71401 agcagataga ggatattgtt caccgtatac ttttcctgta ttttcagacg tttttgcctc
    71461 tagtacttgt ttatctgttt gttctagcaa agcaccatct tgtccaaaat agtaccactt
    71521 ctcctgaagg ccaatttcat taactggttg gttatcgaat aaattatcac gataacctgt
    71581 tccaggaatt tctaagtatt gccaaccgac aaccatctct ccaatatcac caaaatagta
    71641 agttttaccg tctattttat gccaatagat tgctttatga tcatctttta cataatattt
    71701 tctattatcc ttatcaacaa atcggccacc tgtggtattc gcaaataccg tatttgtagc
    71761 tagcaaacca aagaaaaaga ctgctagtag aacttgcatc atttttttca aaagtttcat
    71821 ctatatatcc tcctaaaacg attgtagcaa agacccgact gcatgtcaat atataaaaac
    71881 tcctcaaaaa agcagttaca caactgcaac tgcttttcta ttcttgcatg gtatatccaa
    71941 taccacgcac agttttaatg tagctttttt gtcctttaac atcaagcttg ctccgtagat
    72001 agcggatata gacatctacg atatttgtct cggtcgcact ttcatacttc caaacacttt
    72061 ccaacaattg ctcacgagtc aatactttct tgcttcccat aagtgtcgcc aaaaggtcat
    72121 actcacggcg ggtcagagca atcatctctt caccacgata aaccgtgtga tgttcaacat
    72181 ctatcctaag attgcggtag gtccttggaa ctttcatcag actgcagtgt tgatcaatga
    72241 agtcccgacc tcggaagatc gccgaaatac gcgctaccag attttcgata aggactggct
    72301 tatagatgta tgaaactgca aaacgctgaa caacttccag ctcttcttgc aagtcttccc
    72361 aatgatctaa aatcatgatg actgaggcag gtttagttcg gctcaatttt tctgcaaaat
    72421 cctgagccat catatctccc agattaacgt tcaataacat caaatcatag tctgtctgaa
    72481 gagccatgga gagggctttt tgcccctcct ctaccagatc aacccgatac tgctctttct
    72541 ggagttccaa acttaaaaaa tgagctagat ttcgttcttt ctcaagtaat aaaatccgtt
    72601 tccccatggc tgacctactt atttttcgtc ataccaagag tagtggaagg ttccttcttt
    72661 gtctttacgt tggtaagtgt gagcaccaaa gtagtcacgt tgtgcttgga tcaagttagc
    72721 tggaaggtca gctgaacggt agctatcaaa gtaagtaata gctgctgaga aagttggcac
    72781 tggcacacca gcttgaaccg caagagctac gatatcacgc actgcttgtt gatacttagc
    72841 agtaacatcc aagaagtatt catccaaaag aaggttggca aggtctgcat cacggttgta
    72901 agcatctgta atcttttgca agaaacgaga acggatgata cagccatcac gccagataga
    72961 tgcgatatct gcaaatggca agttccagtt gttttcttta gaggctacac gtaattgagc
    73021 aaatccttgt gcgtatgaaa tgatttttga aaagtaaagg gcttgacgga tcttttcaat
    73081 caattcagcc ttgtctcctt caaagttgaa ggcagctggt tttggaagca ccttgctagc
    73141 atgtacacgt tcttctttgt aagttgaaat gtagcgtgca aacactgact cagtaatcag
    73201 tgacaatggt acaccaaggt caagagatga ttggctagtc catttaccag ttcccttgtt
    73261 acctgcagca tcaaggatgt agtctacgat tggtccatct tggccttcat cgtctttacg
    73321 gctcaaaata tcagctgtga tttcgatcaa atagctgtct aattcaccct tgttccactc
    73381 agtaaagatt tcagccatat cctctgcaga aaggcctagc aagtgttgca tcaagtcata
    73441 gctttctgcg atcaattgca tatcaccgta ctcaatacca ttgtgaacca ttttcacata
    73501 gtgaccagct ccatcagggc cgatgtaagt cacacatggt ttgccatctt ctggtgcttt
    73561 agctgagatt tcttcaagaa catccgcaac caattcgtag gcctcttttt gtccaccagg
    73621 catgatagaa ggaccttcaa gggcaccttt ttcaccacca gaaaccccag taccgataaa
    73681 gttgatacct gagtttgcca attcttcatt acgacggatg gtatctttgt agaaagtatt
    73741 tccaccgtca atcaagatat cacccttgtc aaggtatgga agaagggctt ggatagtagc
    73801 atctgtacca ggtccagctt gaaccatcag catgatacga cgaggttttt cgattgagtt
    73861 tacaaaactt tcaacgtcat agcttggtac aaagttcttt tcaggatggc aagcaatcac
    73921 atcttccgtt ttttctttac tacggttgta gatagcaact gtgtaaccac gtgattcaat
    73981 attaagggca aggttacgac ccattacggc catacctaca acaccaaagt tagcttttgt
    74041 catttgacac tcctcttgtt tcatttgttt tattttatca tttttacttt tgaaaagaaa
    74101 gaattttgta acgactgctt agtaatccaa gtcatccgca tgaccagcgc catttccgac
    74161 aaagtagcct gtcttacagt taagggtaaa gagataggtt ccatctggct tgtagaggtt
    74221 gtaataacca ttgccgttaa cgatattgac acgttcaagg atatattggt ctccagtgat
    74281 atagccacgt gaacgtgaag ttgctagaat ttgttccaag acaccatccg caaaatccca
    74341 ggcagagtta ttactatcat caatagcaga ctgattatag gcaacacgac tggcacttct
    74401 ttgaacagca acccctgcac tcgagagacc catattgact tcactgcgac tacttctagt
    74461 ctcatttgaa ctacttggtt ttggctcact agtcgtattt gagcttgctt gactagagct
    74521 tgagctgcta gtttgacttg aacttgagct agaagtactt gtttgctggc tcttaccaag
    74581 actgatagcc ttacctagca ctttatcaag ctccgtattc ccagttttaa tatctgtaaa
    74641 tttagcatcc gatttggctt tggcattggt atccaacaca ccatccacaa tagctggttt
    74701 ttcaaattgt gcattgacat cttgaatggc cttaatttgc gttactagac tatcatattt
    74761 agatttggca agcgtatgtt cacgactacc ttccagctta tcaagtaaag tcttgagttg
    74821 actcagttta tcaaactggc tatttttcaa agccgtttta ttgctatctg tgtaaaaggc
    74881 gtcataaagt gtattaaaat catccacatc cgattgattg gctgtagttg attgagaagt
    74941 ttcaatttcc ttagtcgaac gagccacttg acggtagaca taataagcac tgacacaaat
    75001 aattactgat acaagcgcca aaacggtcaa aataaagcct tttttacttt tcttttctga
    75061 gtcctcttga tccagacgag aaaggttttg ctcctcttcc acttcttcag tcatttctgt
    75121 tggattttca tcatctagca atagaggatc caagccttgc tcctcatcgt ccagaggcaa
    75181 gggtagtaag atgtcttcag aagatggaac ttcctccgaa gaagcttctg acttctctac
    75241 agcctcacgc atctcttgaa ttaaatcatc cagactctga gtttcaacga actcctcttt
    75301 tttgtattga cgagtcgcaa acttatccgc ctcaatttca tctctgtgtt gcttaacata
    75361 cttgtccaaa atggaatcct caggcaagac tcctgcttcc acttcttcat ttttacgaat
    75421 agcttgacca actgttagct cttttgcttc atcaaaatca aattgcggtt cttgaccttc
    75481 ttttttatga cgatttcgtc tttttttact catgagtatc cctttctatt ttacctcttg
    75541 ccgtttgaca cgctgaccaa aatattgata tagatccact ttcaaggttc cgttgtataa
    75601 cttacgcttc ttatctgctt ggctaccata cttgctttca aaagcttcat cactagtcag
    75661 gataaatttg ctccaagttt tcagcggtgc aaatacttgc cccatctcag catagagctt
    75721 ggtcacccct gcatcatctg acaaacgttc accataaggc ggattggaaa tgattactcc
    75781 attgatttta tcggaacata aatcctgcac gcgcatctgc ttaaaagtaa tgtctcctgc
    75841 aacaccagct acctgagcat tggccttagc aatttccacc atgcgagcat caatatcaca
    75901 gcccatgata tccagctcaa gctcacggtc tactttttta gccgcttctg tgcgcacttc
    75961 ttgaatcaag cgatcgctga tccagttcca ttcctcaaat gcaaaagaac gacgaagacc
    76021 tggcgccatc tttctagcaa tcataactgc ctcaatacag aaagtccccg aaccacaggt
    76081 cggatcaatc aaaggcttgt ctggatacca gttagaaagt tgtaaaatgg ctgctgccat
    76141 attttccttg ataggagcgc cacctttttc ggtacgataa ccacgtttaa agaggctaga
    76201 cccggtcgta tcaatcatga cagttgccac atctttgaga atagagacct caatcttaaa
    76261 ctctggacca ttctccatca gaggaacccc ttctgggcga gcatagtgtt tctgcaattt
    76321 cttgacaaca gctttcttag aaatagcctg aacactgggc tcattgtgaa gtttggactt
    76381 aacacattta gcttttgaaa tcgggaaccg agctccaagt ggtaaataat tttcccaatc
    76441 taaagcgaaa actccctgaa atagctcttc aaaagtctta gctgggaacg ttcctacgat
    76501 aattttgata cgatctgctg cccgaagcca aaggttggtt tcgataatag ctctcacgtc
    76561 tccttgaaaa cgaacacgtc cattttcaac ctgacaatcg tagcccaact ctcgcatttc
    76621 acgaccaacg acagcctcaa gccctgctgc cacagttgca attaaattaa attctttttt
    76681 catgttacag tcttgcaaga cctttctata tgtccacttt aaaaaatgag gttgagaaaa
    76741 tttctcagcc ccaacctata tgcaattttc tataagccat gttttgttcc agaagtgact
    76801 aggaccactt ccttcgataa tcatctgtct accactaaca gctctagctg atagcagtca
    76861 gaatactacg ttcgtttccg cgtactccat gccccgacca aaatttgggt tgctagcttg
    76921 aggggtttac cgcgttccac tctctctgtt tccagaaaga ctccgtcact gtggcacttt
    76981 caagcctact ctggcctatc caaggactta gccatttcaa ctgccgtaac gatttctcgt
    77041 ccctaggctt atggtttcgc ctagcacaaa cactacaggc atcacagcct gtgctagcat
    77101 ggactttcct catgagaagc aattctcctc acgcgattat ccaaaaattg cacatctcaa
    77161 ataactactt aaaaatctga gttatctaaa atttgtttac caaaaacttc tttttccaat
    77221 ctattcaggc gtttcaaaat atcaaaattc gtcatagaac ttgtaattgc cgcttcaagg
    77281 ggttctgctt gaactggtga aggtttcggt ttacgagtta attcttcctt caaatccgca
    77341 atttcctgac gaagtgactt gaccaaggca gcataggttt catagtcctt gatgacatcg
    77401 tctaaaaact cgtcaacttc tactttatta tagccacgga cttcacgtcc aaactcttgt
    77461 tcaaaaatat ctttcgctga aaaaataata cttgccatgt ctctctccat tctcgcttgc
    77521 tagtattatt atataaaaaa aggcaaacaa aaatcaaggt caaagcttca attttcggaa
    77581 aaattttcag caagttcatt taattcatca aatgttaatc tctttataaa atagtcctct
    77641 tgatttttca tcttttggta aaaataagct agttttgttt cattttcttc atcataaaaa
    77701 agataggaac tagtcgtgtt ttccagcaaa aactgctggt aatctcttaa ctgccccttg
    77761 tgttcatagc gaggataggc atatttgaca aagtctacct gcttaaagcg actcagtttc
    77821 atctgattgc cttcattcca attttcccca tgggtttcaa aagcaaaaat ggtggccaac
    77881 tggaaaccgt attcagtttt catctcctga gcaacctcta aaacccaata ttcaaaaccc
    77941 aaactccctg taaacacaag ccaagacacc ccatctgctg ccatagcctc taaatcttta
    78001 cgtatcgctt ttttaatcaa tttaagacga ggatccttat cagaaaataa acccaaatca
    78061 aaagcagaat agcctaaaac caaagctgta gccattttta accctttctg tgcaaattat
    78121 ggtataataa agtgatgtta ttgtaccaat aaggagaatt atggtcaact atccacataa
    78181 agtttcatca caaaaaagac aaacatctct ttctcaaccc aaaaatttcg caaatcgagg
    78241 aatgtctttt gaaaagatga tcaatgctac caacgactac tatttgtctc agggcttggc
    78301 tgttatacat aagaaaccaa ctcctattca aatcgtacaa gtggactatc cacaacgaag
    78361 tcgtgccaag attgttgaag cctattttcg acaagcttca acgacggact attctggcgt
    78421 ttataatgga tattacatcg actttgaagt caaggaaaca aaacaaaaac gtgcgattcc
    78481 gatgaaaaat tttcatccac atcagattca gcatatggaa caagtccttg cccaacaagg
    78541 aatctgcttt gtccttcttc acttttcttc tcagcaagaa acctacttat tgccggcatt
    78601 cgatttgatt cgcttctatc atcaagataa gggacaaaaa tcaatgccac ttgaatatat
    78661 tcgagaatat ggatatgaaa tcaaggctgg tgccttccct caaattcctt atctcaatgt
    78721 tatcaaagaa catttattag gtggtaaaac aagatgaaca aaccaacgat tctgcgccta
    78781 atcaagtatc tgagcattag cttcttaagc ttggttatcg cagccattgt cttaggcgga
    78841 ggagtttttt tctactacgt tagcaaggct cctagcctat ccgagagtaa actagttgca
    78901 acaacttcta gtaaaatcta cgacaataaa aatcaactca ttgctgactt gggttctgaa
    78961 cgccgcgtca atgcccaagc taatgatatt cccacagatt tggttaaggc aatcgtttct
    79021 atcgaagacc atcgcttctt cgaccacagg gggattgata ccatccgtat cctaggagct
    79081 ttcttgcgca atctgcaaag caattccctc caaggtggat caactctcac ccaacagttg
    79141 attaagttga cttacttttc aacttcgact tccgaccaga ctatttctcg taaggctcag
    79201 gaagcttggt tagcgattca gttagaacaa aaagcaacca agcaagaaat cttgacctac
    79261 tatataaata aggtctacat gtctaatggg aactatggaa tgcagacagc agctcaaaac
    79321 tactatggta aagacctcaa taatttaagt ttacctcagt tagccttgct ggctggaatg
    79381 cctcaggcac caaaccaata tgacccctat tcacatccag aagcagccca agaccgccga
    79441 aacttggtct tatctgaaat gaaaaatcaa ggctacatct ctgctgaaca gtatgagaaa
    79501 gcagtcaata caccaattac tgatggacta caaagtctca aatcagcaag taattaccct
    79561 gcttacatgg ataattacct caaggaagtc atcaatcaag ttgaagaaga aacaggctat
    79621 aacctgctca caactgggat ggatgtctac acaaatgtag accaagaagc tcaaaaacat
    79681 ctgtgggata tttacaatac agacgaatac gttgcctatc cagacgatga attgcaagtc
    79741 gcttctacca ttgttgatgt ttctaacggt aaagtcattg cccagctagg agcacgccat
    79801 cagtcaagta atgtttcctt cggaattaac caagcagtag aaacaaaccg cgactgggga
    79861 tcaactatga aaccgatcac agactatgct cctgccttgg agtacggtat ctacgattca
    79921 actgctacta tcgttcacga tgagccctat aactaccctg ggacaaatac ccctgtttat
    79981 aactgggata ggggctactt tggcaacatc accttgcaat acgccctgca acaatcgcga
    80041 aacgtcccag ccgtggaaac tctaaacaag gtcggactca accgcgccaa gactttccta
    80101 aatggtctcg gaatcgacta cccaagtatt cactactcaa atgccatttc aagtaacaca
    80161 accgaatcag acaaaaaata tggagcaagt agtgaaaaga tggctgctgc ttacgctgcc
    80221 tttgcaaatg gtggaactta ctataaacca atgtatatcc ataaagtcgt ctttagtgat
    80281 gggagtgaaa aagagttctc taatgtcgga actcgtgcca tgaaggaaac gacagcctat
    80341 atgatgaccg acatgatgaa aacagtcttg agttatggaa ctggacgaaa tgcctatctt
    80401 gcttggctcc ctcaggctgg taaaacagga acctctaact atacagacga ggaaattgaa
    80461 aaccacatca agacctctca atttgtagca cctgatgaac tatttgctgg ctatacgcgt
    80521 aaatattcaa tggctgtatg gacaggctat tctaaccgtc tgacaccact tgtaggcaat
    80581 ggccttacgg tcgctgccaa agtttaccgc tctatgatga cctatctgtc tgaaggaagc
    80641 aatccagagg attggaatat accagagggg ctctacagaa atggagaatt cgtatttaaa
    80701 aatggtgctc gttctacgtg gaactcacct gctccacaac aacccccatc aactgaaagt
    80761 tcaagctcat catcagatag ttcaacttca cagtctagct caaccactcc aagcacaaat
    80821 aatagtacga ctaccaatcc taacaataat acgcaacaat caaatacaac ccctgatcaa
    80881 caaaatcaga atcctcaacc agcacaacca taacatttat cacccagatt tttctgggtg
    80941 attttgtcat agcactattg tatttatgtg cttaacaaaa gcctgagaag acatcttctc
    81001 aggctttttc tgtactataa acctcattgg aaaagataga gactgcttcc gtaatcttgt
    81061 taagaggttt tactaaatac tagtctttct tcgtttttac tacaaagaga gcagataggg
    81121 ctagactaac acttgctagg aagagggctg tgtcagattg actctcacct gttgctggca
    81181 agatttgttc aggtgtttct ggtctatcta tttcttgctt ataatctggc gtcttacctt
    81241 gattggaaac taaagagcta agtttaaact caggtttctc tacagttgga gcatctggtt
    81301 tcgtagcaga atcttttaat tggttgagat aatctgcaaa gtattccacc attctttccg
    81361 tcaagagatg gttatccgtc gcatatttca tgcttgcctg aacgctagct acttcctctt
    81421 gattgtcttt gtctgttaat ttctgagcct tagccaaagc tgcttcatag cctgacaagt
    81481 caagaggtgt ttctgctacc tgtggacgag taaagataag ttccgctgca gattggtatt
    81541 tatcgccacc atctccgtaa gtcttagtac ctgtaaggac aattttctta gccttaattg
    81601 tcttaccaaa atcaatgtct tttggcttat tgttatctgg ccaatcagtt gcagtaaagg
    81661 tatgctcctt gccagactca tctgtcacaa caagtttcac atcacgcaag ttaccatttg
    81721 aacctgatcc acgtggaaca taacgaagtc cagtgatttc agttggttct ttcaagacca
    81781 tggttgcagg cttgcctaca tctccaccat tccaagatgt atgccataga ctagacacat
    81841 tgccatcaaa ggcatttgca agaccttctt gagcctgagc aggagctgta agacttgcaa
    81901 agtcatctgc taccaaagcc gttttcttct gaaccaaagc attcttcaaa gcttcaatct
    81961 tggcaatctc tgcacgcgct tcttccacac tgatatcatc atcggcctga ctgaggttaa
    82021 agaccgcctc tttcaaagca tccatagact ctttggtgta gttagtcatg gcaaccgttg
    82081 gcaagtagtt cttcagagca ttttctgtca acatcttacc tgttagggta atttcttcga
    82141 tttgaagatt atccatcatg aagtcgttat aaccacggaa gttggcattt ccaccagaat
    82201 caccacgagt attacttgca tttccagttg agtagatacc tacccaagta tcgcctgttt
    82261 ctgcacctgt cacaaggaag gttgccttct tggctttctt agaatctgtc caagtatttg
    82321 gcaattcatg catttccaag ttgcttgctt gagtaccacg acgacctgac tggaattctc
    82381 ccttaccgac tacaaaagca taggtattgt ctgatcctgc ttcgtattca aaggttacac
    82441 ggtaggtctt acctgcttca aaacggaagt tttgtgggat ggtttggtaa accaagttac
    82501 gacggctcac tagtccattt gtcttgagtg accaatttcc ttcgataaca tcatcgactt
    82561 tcttaccatt ccaaccacgt tgtgtatatg gattgtgttt ttcagacaag tgagtgcggt
    82621 tatcttcaac accttcgaca ccacccacta caaatgggaa gataccctga gcaacatttt
    82681 caaagtcttg cttgaaggtg cctttacctg tatcatgctt gtctccgtac atgcttgaat
    82741 tgttttcaaa ggtacgaatt tcatcaaagt aagttgcttg atcaccagct tcacgactca
    82801 atgtcagagt aacatttgat acgtccgatc cagttgtaaa gaaggcgtac atgttttgga
    82861 agtaacttgt atcgtcaact gtagcattgt tacgacgtgt attgtgggcg taggctttta
    82921 catagttgag ggcgagagac ttattggtat aagtagtcac ttctttttca ccagtattta
    82981 cagtgacgct cgccttggca ttactacggt tatcgacacc gacataaacg gcatacttgg
    83041 tatttggttt caagccagtt aatttctgag tgagactaac tttttctttg tttccttgaa
    83101 tacgaagcat atcgtttgcc ccttgagact tgacaatttc tgccttagaa gcatcgcctg
    83161 aaatggtcca atgtttcaag gtaccactgt taaatccttg gtcatagatg tgcatgcctt
    83221 cgctccatga catttcagga ttggtttgtt tcgaacgata gagaacgtat ggttgatttg
    83281 ctagaagatc tagagtaatt ttaccatctt ttacagttag ttcttgctct tctgtcttac
    83341 cttggtcagt tagcttgtaa aggtaaacct tgctctttgc ccaatcgctt ggaagggtcc
    83401 aagttgttgc accggcctgc gtattgaagt agtacatctt ttccttatca gtagaaagtt
    83461 tcttaccatt tgcatcccag ttccaaggag tcaagtaagc tgaaccatct tggatgacac
    83521 gtccgttgag cgttactgta cgttcgcgat attgtggact attgacatca tttgacttac
    83581 gagttacaac tactttatta ttgtcagcat ctaccaattc cactcgcatt tctggagtcc
    83641 atttataggt gctaccgtta tcggtcatag tcaccggtgt accattttcc catttgctta
    83701 cagtgaagtg ttggaaatac ttggtcatga cgtcatgggc aaataagttg gttacatagc
    83761 cattgtagtc acttcttcct tgccagcctt caaagtcttt catgctgtag ccacctagca
    83821 gtggatagtt ggctgcacca ccataacttc tgtagtcccc aacccaagca tctttttggt
    83881 ggttacggat aaagcgggtg atggcactgt tgataccttt attggtgtag ccaccgtagg
    83941 tcaagtcagc tgcccagtga tggaaggtag agtcgtactc accaccatgg ccccactcga
    84001 tcgcaaagcg ccagccttgt ttgttaattt ctttagcaag aacgtgggta gcccaggcac
    84061 cgttatcacc tgattgacca ttaccccaaa cgtccacata gataaagtcg agaccgtcac
    84121 caagtttttt cttcaaatct tcccaacgtg ccaaacgacc atgagctagg tcataggcag
    84181 catcaatgtt gataccttga tctagccagt tccaaccata gctatagctt ccatctggat
    84241 tcttacggag aattttttca ttgaagtatt tagactcagg ataagtttct gaagcgttaa
    84301 cgtggatacc tagatgagct ccatatttct tagccttctc aattagggtc ttgaagtctt
    84361 cgacaccacc gatacgctta ccaatatcag catagttcaa gtgaccagag tcatggcctt
    84421 cgctaccata tcctttaagg agaacacctt gcccaagacc atctgtgtgg agattgattt
    84481 tcttgatacc atccaaggtc ataaggaatg ggttttgtgc ttgagaacca aagttcatcg
    84541 cgatacggta agctgtgata tccttaactt tttcccaacc ttgaggattg ttcataatgc
    84601 tacgataagc aatggcacca tcttgccaat caactttctt gtctgcattg gcatcttcag
    84661 tgataacaac cttagcactt ggaagttcct tcgtgtattc tgggaaaaca atgcccttat
    84721 aagctttttc ccattgccat tcagagctat ggattcctac atagttggca tttccgactg
    84781 tttctttata agctgtcaaa cgagtccagt cattcgaacc accaccatag ctattttgag
    84841 agttactcca aacaccagca gcaagcttat ctgtagaaac aaatccatac atgtaaccct
    84901 tagccaaatc cttcattgga ttggttacat cgatatgatc atctccgctg acatgcgtat
    84961 tgtttgacat ggttgcccca tcaaacttag caccagtttg atcactagaa acagagacta
    85021 aagcattgcc gaggaaacta atagaagaaa gtagttttct ttcgtcatca atcttttgac
    85081 ctggagtgac ttgattgtgg ttgacaatct tggtcacatc aaagtgcaat tgattgtcca
    85141 caacttgcaa gcgtactgtt atttccgcat tgattaagtg agcatcatcg cgaatcttca
    85201 tcaagtactc tgctgttgtc tcattgattt tcttataagt gacttcaggg gtgattcggt
    85261 ggttattgat aaagacttgg ttgaactgtt gcacctgtcc tggcaaagta tgtccattca
    85321 agctgtattc cttgacacga gggaaggctt ggtcaatcac tgctttgagg accttagact
    85381 gaatcgtgtc ataagtcacc ttgctatcat caacttcagg acctgtttct ttttcagcag
    85441 gggtatcctc tgtttttacc ccctcttggt tatccgtttt aacgctaaca actgttcgct
    85501 catcgtcata agagcccgcc ttgagaagaa tcttcttctc atttttaaga tggtcattga
    85561 ccgcagctgg tagagtcact gtgtcaaaga gattgacatc gttattgctg gcatttagct
    85621 gaccgtctga cttgagagtg atagagagac ggtttgttga tcctgtttca ggagcagcaa
    85681 cacgactacc tctataccaa gtgctagttg ttggagattt atactcccag aaccagccat
    85741 ccttgtcata accgacaaaa acattattat tggtatcttt aaatttcaag aagacaccaa
    85801 agcgtgattt gcccttttca gaatcttctt tgaaggttaa atcaacagtt gcatttccat
    85861 tggcatcaac ggtcaagccc ttcttttcaa acagggcttg tttgcctgcg ttatcatttt
    85921 gagcagttga ggatagttgg ttgtagcgga cacctttttc ttctcggata gtgactgttc
    85981 cttgttgttc ttttttctct accgtttgcc attcaggggt taccgtctta ggtgtttcag
    86041 gtttagcagc tgcaggttta tcctcttttg gtttttcttc agccggtttt tctttttcaa
    86101 gtgctaatag ttcttcttct gtcttaggtc catctgtaac ttctggagaa ccttggtctt
    86161 ctcccacctt aggcgcttca aaatcacgct catcattctc ttttgctgtt gcaagagcag
    86221 tagctaaatc agctggtaaa ttcgccgtag aaccagactg cacgctatct gcaagaaccg
    86281 gacttgtccc aaagaatgca gctccaatca taacagaagc aacacctaat gaaaatttcc
    86341 gaatactata tttacaacgt ttttcaaata atcctttatt cataaacttc taaatccttt
    86401 catttttggg caagcgttta catttccttt ttaaaaaata ctccttcctc tgaaagtgca
    86461 atgcttaacc ctgataaata aaaaataatt atacttttaa tataacaaat aataactgat
    86521 aaagcaatag gaaacaagta aaattaacaa aaattttctc tattctgaca aaaagaggct
    86581 ccaacttttg ggggtcagta catttagaat ctttctttac aaatgtaaaa aaggattcag
    86641 cattcaagag aaatactaaa tcctttctta tattttgcaa cagttatttc acatgttttg
    86701 cgagatcttc ttgagccttt ttattagact cttctttttc tttcatccat ttttcctgag
    86761 ctttttggta ttcatctaca gtgactgcct tgtcttgaag ttccaagtat ttatataaga
    86821 ttggttcact tgtaccttta tttcctgaca atgcaaatgg tattgtaaat ggtaccatct
    86881 tagacaagat tgggcgccct gtacgagatg tagttggaat aatcaaagca ctatctgtca
    86941 accaagcttg ggctgcagcg tatttatcat agcgtttagc aacatctgta gcctcatcac
    87001 cagcctcagt aaccaatttt tcgtagtcat atagacctac ttttttagca gctacattat
    87061 cttcccctga gtcaaaccct aaatatgttt tagtactttc tcctacagat ggtttgatga
    87121 tatcaaggta agttgatgga tcggcaaagt ctggacccca accgacatta tctgataaat
    87181 cccagtcttc gccagcagca ttttcagcaa aatatgtaat attgtttact tcgtcttttt
    87241 gtagttgttg gatatcaata atgacattat cagctcctaa agttgcttcc aaggattgtt
    87301 tcatagattg gacgcgctga acttttgtag ttgctgtctg gtcaactggc atatccaaat
    87361 gaattgggaa tgtcacacct tctgcttgta aggctgattt agctttagca aattcagcct
    87421 tggctttttc tggattgtaa agaccatcct gagaatctgc aagattaaca tccttccatt
    87481 catccccata agtgaccaat ttctctttga ccatatcgcc aaagttttta ccatctgctt
    87541 gaacaaatgt tggtggcaca aagagattac gcaagatttt acttgctcca gtttgtccat
    87601 tcaactgaga ggcataggct gtacgatcaa aaccaaaggc aatagcctga cggaaatcct
    87661 tgtttaagag agccttttta gtcgatgcct tttgttcgtc gctggtctta gatgtgtatt
    87721 tataggactg acggtcaata tttgtaccaa ctagatacgt aatagagtct tgttgagtat
    87781 agacaatatt gtccttcata ctcttctcaa gctctgcgaa acttgcactt gttggataga
    87841 gacgagctgc tgtaaggcta ccatctttaa agttttctgc aggtttgctg gtatcttgac
    87901 catcccagaa tgacaattta actttgtcaa tatgcacatt gtccttatcc cagtagttcg
    87961 gatttttcgc aaattcaaca gaagatttgg tcacaatgga tttcaacaaa taaggaccgt
    88021 tatacaagag actacttgga tccgtagctt tggcaaaatc atcccctttt gaattcaaaa
    88081 actcttcatt aactggcgca agcacaccca tggttgtctt agaattccag aagctttctg
    88141 gtttgttcaa agtgtactga actgtctgtt catccagaac cttaattcct acttgtgaga
    88201 aatctttgat ttcccctttt acataggcat ccaacccttt gattgattct tgaacaaggt
    88261 aaagagcatc tgatttttta tcagcagcat attttagtcc tgttacaaag tcttgagctt
    88321 tgactgccgc gtattcttcc ccttcagaag tataccattt tgcatcctta cggatagtat
    88381 aagtgtaagt caatccatcc ttggatacag accaatcctc agccatagac ggcacaaagt
    88441 tcccgtagcg atcattttct agcaaaccat caaccacgtt actggtaata tttgctgtcg
    88501 cagccttagc agttgtcaaa tagttgaggt tatcagggtc tgtctcataa atgtatgaga
    88561 atgtcttctc acctttagtg cttgaacctg atccagagca tgcagctaaa gtagtcgccg
    88621 ccaataatgt cacgcccgca agggcaaata gttttgaact tttcatcatt ttctccttta
    88681 aaactttctc tccattataa actcttttca gaaagatgtc aacagaattt tcagaatttt
    88741 tgtgttaatt tggtatattc tgaaaagaca aaaaaagaga agacagtgat tgtcctctcc
    88801 agatgttagt tgacaaagag ccacattata aatctaaaat aatttatttt aatttaatat
    88861 acttttgtgg taataaaaca atattcaaaa atggaatttt tttcaatata taagttgcta
    88921 gtatggataa ataccagcct agcacaatcc caacaacaac gtgaagaaaa actgagttta
    88981 ttcccacttt caacattaga atccgaatca tgctacaaat tggtgcatga agaatataga
    89041 tccctaaact atctttcccg tatttagtga aatataggaa agttttagga aaatttttct
    89101 ccattttagg aaaaatcgca aaagcaacta atacacagac aataaaagca atcccccaca
    89161 aacctgggtt aatatagctt acataatcct tcttagaccc tacttcataa aacaagaacc
    89221 aagcgaacat ataaataaaa tcaaataaca caaagaaaaa aagaaatttt ttcaaattaa
    89281 ttttatcaaa gtgaatttca ctcaatacac tgccaagaaa gaaacaaatc ccccaaacca
    89341 acgtccgttg cacaataaaa atatcagttt gaataaatag tgtgaaaata taggcaaaaa
    89401 cactaactaa caaaagggac ttacgatttt tgaaaacaac agatagtaaa ccataaacta
    89461 tcaatatcga ccataacgta tatagatacc atgaaactcc cagaggaaat ttatagatat
    89521 tcaataggtt aaatatcata gtgggtactc ggacagaggc acccgcaacc ttttgaatac
    89581 aaaagtgaat aattgaataa aaaatatata gtatgcctaa aatatccgaa gcgtttacga
    89641 tgatttcgat aggttgttga aaacatttta aacgttttta ctttggcaag gatgttctca
    89701 accttgcttc tatccttaga cagtgcatgg ttataggctt tatcttcagc ta
//
LOCUS       DBERCW010000005        85897 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.005, whole genome shotgun sequence.
ACCESSION   DBERCW010000005 DBERCW010000000
VERSION     DBERCW010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 85897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.005"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            226..6660
                     /locus_tag="ACL72M_000450"
     CDS             226..6660
                     /locus_tag="ACL72M_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS0715634.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            7292..7768
                     /locus_tag="ACL72M_000451"
     CDS             7292..7768
                     /locus_tag="ACL72M_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0715635.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7806..8111
                     /locus_tag="ACL72M_000452"
     CDS             7806..8111
                     /locus_tag="ACL72M_000452"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0715636.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8159..9634
                     /locus_tag="ACL72M_000453"
     CDS             8159..9634
                     /locus_tag="ACL72M_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGS0715637.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9984..16685
                     /gene="bgaA"
                     /locus_tag="ACL72M_000454"
     CDS             9984..16685
                     /gene="bgaA"
                     /locus_tag="ACL72M_000454"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGS0715638.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(16933..17379)
                     /locus_tag="ACL72M_000455"
     CDS             complement(16933..17379)
                     /locus_tag="ACL72M_000455"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0715639.1"
                     /translation="MFDKEQKRGYKQSAKNLANWHYNDKEDSYIHPDGWCYRFHHIKY
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQDRQIFAQRKI
                     DVEPVFGQIKACLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(17544..17789)
                     /locus_tag="ACL72M_000456"
     CDS             complement(17544..17789)
                     /locus_tag="ACL72M_000456"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0715640.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEERHFYTS
                     YHAFGRPSYHPKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(18000..18359)
                     /locus_tag="ACL72M_000457"
     CDS             complement(18000..18359)
                     /locus_tag="ACL72M_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGS0715641.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            18451..19407
                     /locus_tag="ACL72M_000458"
                     /pseudo
     CDS             18451..19407
                     /locus_tag="ACL72M_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            19391..19948
                     /locus_tag="ACL72M_000459"
     CDS             19391..19948
                     /locus_tag="ACL72M_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0715642.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            19941..20195
                     /locus_tag="ACL72M_000460"
     CDS             19941..20195
                     /locus_tag="ACL72M_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715643.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            20207..22261
                     /locus_tag="ACL72M_000461"
     CDS             20207..22261
                     /locus_tag="ACL72M_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGS0715644.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            22440..23300
                     /locus_tag="ACL72M_000462"
     CDS             22440..23300
                     /locus_tag="ACL72M_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGS0715645.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            23511..24221
                     /gene="ccdA2"
                     /locus_tag="ACL72M_000463"
     CDS             23511..24221
                     /gene="ccdA2"
                     /locus_tag="ACL72M_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS0715646.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            24241..24807
                     /locus_tag="ACL72M_000464"
     CDS             24241..24807
                     /locus_tag="ACL72M_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGS0715647.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            24818..25930
                     /gene="msrB"
                     /locus_tag="ACL72M_000465"
     CDS             24818..25930
                     /gene="msrB"
                     /locus_tag="ACL72M_000465"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS0715648.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            26198..26935
                     /locus_tag="ACL72M_000466"
     CDS             26198..26935
                     /locus_tag="ACL72M_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0715649.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            26932..28623
                     /locus_tag="ACL72M_000467"
     CDS             26932..28623
                     /locus_tag="ACL72M_000467"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0715650.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            28739..29302
                     /locus_tag="ACL72M_000468"
     CDS             28739..29302
                     /locus_tag="ACL72M_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGS0715651.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            29324..34993
                     /locus_tag="ACL72M_000469"
     CDS             29324..34993
                     /locus_tag="ACL72M_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS0715652.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEALKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            35054..36775
                     /gene="pabB"
                     /locus_tag="ACL72M_000470"
     CDS             35054..36775
                     /gene="pabB"
                     /locus_tag="ACL72M_000470"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGS0715653.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            37306..38421
                     /locus_tag="ACL72M_000471"
     CDS             37306..38421
                     /locus_tag="ACL72M_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS0715654.1"
                     /translation="MSKGDFIDPKTQFKHQYRGESPVFRIRNRKYVELGTTDKKLDER
                     RDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSVNSNLLNSFGEKAKKVLIRSKL
                     INVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDLTDGEYKYVAYESQQYTDPQTT
                     LTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPKPDEKPKPSAPQQEKTKPTVQS
                     GWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYVQNAWVGNYYLKSGGYMAKSEW
                     IYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAKSEWVYDSNYKSYYYLTSEGSY
                     ARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK"
     gene            38508..39427
                     /locus_tag="ACL72M_000472"
                     /pseudo
     CDS             38508..39427
                     /locus_tag="ACL72M_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
     gene            39562..40521
                     /locus_tag="ACL72M_000473"
     CDS             39562..40521
                     /locus_tag="ACL72M_000473"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGS0715655.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            40618..41457
                     /locus_tag="ACL72M_000474"
     CDS             40618..41457
                     /locus_tag="ACL72M_000474"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGS0715656.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(41505..41675)
                     /locus_tag="ACL72M_000475"
     CDS             complement(41505..41675)
                     /locus_tag="ACL72M_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGS0715657.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            41796..42680
                     /gene="miaA"
                     /locus_tag="ACL72M_000476"
     CDS             41796..42680
                     /gene="miaA"
                     /locus_tag="ACL72M_000476"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGS0715658.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            42673..43911
                     /gene="hflX"
                     /locus_tag="ACL72M_000477"
     CDS             42673..43911
                     /gene="hflX"
                     /locus_tag="ACL72M_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGS0715659.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            43904..44527
                     /locus_tag="ACL72M_000478"
     CDS             43904..44527
                     /locus_tag="ACL72M_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGS0715660.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            44542..45471
                     /gene="rnz"
                     /locus_tag="ACL72M_000479"
     CDS             44542..45471
                     /gene="rnz"
                     /locus_tag="ACL72M_000479"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGS0715661.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            45492..46247
                     /locus_tag="ACL72M_000480"
     CDS             45492..46247
                     /locus_tag="ACL72M_000480"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS0715662.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(46301..47209)
                     /locus_tag="ACL72M_000481"
     CDS             complement(46301..47209)
                     /locus_tag="ACL72M_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS0715663.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            47273..47542
                     /locus_tag="ACL72M_000482"
     CDS             47273..47542
                     /locus_tag="ACL72M_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGS0715664.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            47542..47922
                     /locus_tag="ACL72M_000483"
     CDS             47542..47922
                     /locus_tag="ACL72M_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS0715665.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            48011..48238
                     /locus_tag="ACL72M_000484"
                     /pseudo
     CDS             48011..48238
                     /locus_tag="ACL72M_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(48278..49003)
                     /locus_tag="ACL72M_000485"
     CDS             complement(48278..49003)
                     /locus_tag="ACL72M_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGS0715666.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            49165..51006
                     /gene="typA"
                     /locus_tag="ACL72M_000486"
     CDS             49165..51006
                     /gene="typA"
                     /locus_tag="ACL72M_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGS0715667.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            51026..51280
                     /locus_tag="ACL72M_000487"
     CDS             51026..51280
                     /locus_tag="ACL72M_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGS0715668.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
     gene            51645..51944
                     /locus_tag="ACL72M_000488"
                     /pseudo
     CDS             51645..51944
                     /locus_tag="ACL72M_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            52027..54048
                     /locus_tag="ACL72M_000489"
                     /pseudo
     CDS             52027..54048
                     /locus_tag="ACL72M_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            54050..54691
                     /locus_tag="ACL72M_000490"
     CDS             54050..54691
                     /locus_tag="ACL72M_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715669.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            54795..56147
                     /gene="murD"
                     /locus_tag="ACL72M_000491"
     CDS             54795..56147
                     /gene="murD"
                     /locus_tag="ACL72M_000491"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGS0715670.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            56151..57209
                     /locus_tag="ACL72M_000492"
     CDS             56151..57209
                     /locus_tag="ACL72M_000492"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGS0715671.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            57219..58418
                     /gene="divIB"
                     /locus_tag="ACL72M_000493"
     CDS             57219..58418
                     /gene="divIB"
                     /locus_tag="ACL72M_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGS0715672.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            58651..59352
                     /gene="pyrF"
                     /locus_tag="ACL72M_000494"
     CDS             58651..59352
                     /gene="pyrF"
                     /locus_tag="ACL72M_000494"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGS0715673.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            59386..60018
                     /gene="pyrE"
                     /locus_tag="ACL72M_000495"
     CDS             59386..60018
                     /gene="pyrE"
                     /locus_tag="ACL72M_000495"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGS0715674.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            60302..60601
                     /locus_tag="ACL72M_000496"
     CDS             60302..60601
                     /locus_tag="ACL72M_000496"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715675.1"
                     /translation="MPRWGSDTTSELEKENASAGINNNDSTGGGKRLNTSIRSAYSGS
                     DITPVYSLGSGSRIVMYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWNPDSY"
     gene            60697..61461
                     /locus_tag="ACL72M_000497"
     CDS             60697..61461
                     /locus_tag="ACL72M_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715676.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            61461..62212
                     /locus_tag="ACL72M_000498"
                     /pseudo
     CDS             61461..62212
                     /locus_tag="ACL72M_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            62222..62920
                     /locus_tag="ACL72M_000499"
     CDS             62222..62920
                     /locus_tag="ACL72M_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715677.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            62917..63564
                     /locus_tag="ACL72M_000500"
     CDS             62917..63564
                     /locus_tag="ACL72M_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715678.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(63644..64505)
                     /locus_tag="ACL72M_000501"
                     /pseudo
     CDS             complement(63644..64505)
                     /locus_tag="ACL72M_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(64517..65275)
                     /locus_tag="ACL72M_000502"
     CDS             complement(64517..65275)
                     /locus_tag="ACL72M_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0715679.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(65276..65953)
                     /locus_tag="ACL72M_000503"
     CDS             complement(65276..65953)
                     /locus_tag="ACL72M_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0715680.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(65913..66581)
                     /locus_tag="ACL72M_000504"
     CDS             complement(65913..66581)
                     /locus_tag="ACL72M_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0715681.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            66807..66941
                     /locus_tag="ACL72M_000505"
                     /pseudo
     CDS             66807..66941
                     /locus_tag="ACL72M_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            67081..68571
                     /gene="lysS"
                     /locus_tag="ACL72M_000506"
     CDS             67081..68571
                     /gene="lysS"
                     /locus_tag="ACL72M_000506"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGS0715682.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            69196..70332
                     /gene="lctO"
                     /locus_tag="ACL72M_000507"
     CDS             69196..70332
                     /gene="lctO"
                     /locus_tag="ACL72M_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGS0715683.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLRLY"
     regulatory      70586..70674
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            70889..71557
                     /locus_tag="ACL72M_000508"
     CDS             70889..71557
                     /locus_tag="ACL72M_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGS0715684.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLIMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            71794..72576
                     /gene="thiM"
                     /locus_tag="ACL72M_000509"
     CDS             71794..72576
                     /gene="thiM"
                     /locus_tag="ACL72M_000509"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS0715685.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPE
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            72578..73207
                     /gene="thiE"
                     /locus_tag="ACL72M_000510"
     CDS             72578..73207
                     /gene="thiE"
                     /locus_tag="ACL72M_000510"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS0715686.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      73416..73504
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            73766..74326
                     /locus_tag="ACL72M_000511"
     CDS             73766..74326
                     /locus_tag="ACL72M_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0715687.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            74327..75712
                     /locus_tag="ACL72M_000512"
     CDS             74327..75712
                     /locus_tag="ACL72M_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0715688.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            75714..76364
                     /locus_tag="ACL72M_000513"
     CDS             75714..76364
                     /locus_tag="ACL72M_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGS0715689.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            76375..77067
                     /gene="tenA"
                     /locus_tag="ACL72M_000514"
     CDS             76375..77067
                     /gene="tenA"
                     /locus_tag="ACL72M_000514"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGS0715690.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            77072..77596
                     /gene="thiW"
                     /locus_tag="ACL72M_000515"
     CDS             77072..77596
                     /gene="thiW"
                     /locus_tag="ACL72M_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGS0715691.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            77596..78399
                     /locus_tag="ACL72M_000516"
     CDS             77596..78399
                     /locus_tag="ACL72M_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS0715692.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            78392..79024
                     /gene="thiE"
                     /locus_tag="ACL72M_000517"
     CDS             78392..79024
                     /gene="thiE"
                     /locus_tag="ACL72M_000517"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS0715693.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(79234..80025)
                     /gene="thiD"
                     /locus_tag="ACL72M_000518"
     CDS             complement(79234..80025)
                     /gene="thiD"
                     /locus_tag="ACL72M_000518"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS0715694.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(80109..80207)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            80391..80786
                     /locus_tag="ACL72M_000519"
     CDS             80391..80786
                     /locus_tag="ACL72M_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGS0715695.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            80797..81168
                     /locus_tag="ACL72M_000520"
     CDS             80797..81168
                     /locus_tag="ACL72M_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGS0715696.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            81178..83421
                     /locus_tag="ACL72M_000521"
     CDS             81178..83421
                     /locus_tag="ACL72M_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS0715697.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            83628..85403
                     /gene="spxB"
                     /locus_tag="ACL72M_000522"
     CDS             83628..85403
                     /gene="spxB"
                     /locus_tag="ACL72M_000522"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGS0715698.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            85514..85861
                     /locus_tag="ACL72M_000523"
     CDS             85514..85861
                     /locus_tag="ACL72M_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0715699.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
BASE COUNT        26812 a        15225 c        18659 g        25201 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 ttagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca gttattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 acatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgca gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctattcgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagact taaagaaact cattaaaaag
     4441 aaatttagag aagttgatga ttttacaagt gaaactggta agagaataga ggaatacgat
     4501 tataaatacg atgataaggg aaatattatt gcttatgacg atggtagtgc cttacaatat
     4561 gaaactgaaa aacttgacga aataaaatca aaaatttatg gcgttctaag cccatctaaa
     4621 gatggacact ttgaaattct tggaaagata agcaatgttt ctaaaaatgc caaggtatat
     4681 tatggaaata gctataaatc gatagaaatc aaagcgacta agtatgactc acattcaaaa
     4741 acgatgacat ttgatttata cgctaatatt aatgatattg tggatggatt agcttttgct
     4801 ggagatatgc ggttttttgt taaagatgat aatcgaataa aagctgaaac taaaattaga
     4861 atgcctgaaa aaaataagga aactaaagca gaatatccct atgtatcaag ttatgggaat
     4921 gtaatcgaat taggagaagg agatctttca aagaacaaac cagacaattt aactaaaatg
     4981 gaatctggta aaatctattc tgattcagaa aaacaacaat atctgttaaa ggataacatc
     5041 attctaagaa aaggctatgc actaaaagtg actacctata atcctggaaa aacggatatg
     5101 ttagaaggaa atggagtcta tagcaaggaa gatatagcaa aaatacaaaa ggccaatcct
     5161 aatctaagag tcctttcaga aacaacaatt tatgctgata gtagaaatgt tgaagatgga
     5221 agaagtaccc aagctgtatt aatgtcggct ttggacggct ttaacattat aaggtatcaa
     5281 gtgtttacat ttaaaatgaa cgataaaggg gaagctatcg ataaagacgg aaatcttgtg
     5341 acagattctt ctaaacttgt attatttggt aaggatgata aagaatacac tggagaggat
     5401 aagtccaatg tagaagctat aaaagaagat ggctccatgt tatttattga taccaaacca
     5461 gtaaaccttt caatggataa gaactacttt aatccatcta aatctaataa aatttatgta
     5521 cgaaatccag aattttattt aagaggtaag atttctgata agggtggttt taactgggaa
     5581 ttgagagtta atgaatcggt tgtagataat tatttaatct acggagattt acacattgat
     5641 aacactagag attttaatat taagctgaat gttaaagacg gtgacatcat ggactgggga
     5701 atgaaagact ataaagcaaa cggatttcca gataaggtaa cagatatgga tggaaatgtt
     5761 tatcttcaaa ctggctatag cgatttgaat gctaaagcag ttggagtcca ctatcagttt
     5821 ttatatgata atgttaaacc cgaagtaaac attgatccta agggaaatac tagtatcgaa
     5881 tatgctgatg gaaaatctgt agtctttaac atcaatgata aaagaaataa tggattcgat
     5941 ggtgagattc aagaacaaca tatttatgta aatggaaaag aatatacatc atttgatgat
     6001 attaaacaaa taacagacaa gacactaaac attaagattg ttgtaaaaga ttttgcaaga
     6061 aatacaaccg taaaagaatt cattttaaat aaagatacgg gagaggtaag tgaattaaaa
     6121 cctcataggg taactgtgac cattcaaaat ggaaaagaaa tgagttcaac gatagtgtcg
     6181 gaagaagatt ttattttacc tgtttataag ggtgaattag aaaaaggata ccaatttgat
     6241 ggttgggaaa tttctggttt cgaaggtaaa aaagacgctg gctatgttat taatctatca
     6301 aaagatacct ttataaaacc tgtattcaag aaaatagagg agaaaaagga ggaagaaaat
     6361 aaacctactt ttgatgtatc gaaaaagaaa gataacccac aagtaaacca tagtcaatta
     6421 aatgaaagtc acagaaaaga ggatttacaa agagaagatc attcacaaaa atctgattca
     6481 actaaggatg ttacagctac agttcttgat aaaaacaata tcagtagtaa atcaactact
     6541 aacaatccta ataagttgcc aaaaactgga acagcaagcg gagcccagac actattagct
     6601 gccggaataa tgtttatagt aggaattttt cttggattga agaaaaaaaa tcaagattaa
     6661 gacaaaagct atagaaaaaa atggtttatg tactgagatt agatagtgag gtgatgacat
     6721 agttttgtga aaacggccat ttataactca attatttagt ttacttcact tcactattga
     6781 tactatttgg agttattaac ggacttagtt tagataacta atgaattgat tgaaagggtt
     6841 agtattgaca atattggtca tattgattag aaaatagagt ctatcaaaat ttaaaggcta
     6901 atagaggtga tgagacaatt tcaaggaatt aagtagcgtt tggttgctta attccttttt
     6961 atttggaagg aagtttttcg taaccgccca ataacgaagt ctattggacg gttacgatat
     7021 gatcactgac ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg
     7081 ctagcttcct agtttactct ttgattttca ttgagtatta gaacagaaaa aatgcttgga
     7141 gtatttgttt gtgtgtttat ttttatataa caaactataa acaaaacaaa aatataaaaa
     7201 aagagacaaa aaagaacaaa aagtaattga caacggtttc atatagtgtt atacttatgg
     7261 cataaagtta atggaaagaa gggaaaaact tatggtatta gattatttct ttgacaaaaa
     7321 ccttgtgttt tgcttagaag cggataatca agaacatctc tttgatcagg ttgcaacttt
     7381 attggaagaa cgagaaattg taactccaac ttatcgtgaa gccttgatca cgcgtgaaaa
     7441 gtcatttcca actggtttag atatggaatt tctaggaaag gacttgccaa atgtagcgat
     7501 tcctcacaca gatattgttc ataatctagc tgagaaagtg gtggttgttc gattagaaaa
     7561 accagtaact tttcacaata tgattgcgcc aggtaaggaa gtagaagtat ctctactctt
     7621 ctttatcatt aacaattcaa gttcaagtca aacgaacatt ctggctcagt tgatggactt
     7681 tttcacagga aatggtcatc ttgaagacct atcaaaaatt tctgaaccag aaaaacttta
     7741 tgcttacatt gctgaagcaa ccgcttaatc ttgtctatta aaaaataaaa tcggaggaaa
     7801 tccaaatgat taaaattctt gctgcctgcg gtgcaggtgt taactcaagt caccaaatta
     7861 aaagtgctct agaagaagaa ctttcaaacc gtggttatga tgttcactgt gatgcagtca
     7921 tggtgaaaga tgtaaacgaa gaccttatga aaggttacga tatctttaca ccaatcgctg
     7981 caacagacct tggttttgaa ccaggtatcc cagttatcga agctgggcca atcttattcc
     8041 gtatcccagc aatgagcgct ccagtatttg acaatattga agcagctatt aaagaacatg
     8101 gattaagcta attctaattt gttaacattc atataacata aaaaagggag gaactgttat
     8161 ggatgcaatc tttgacctaa tcggaaaggt tttcaatccc atcttagaaa tgggtggacc
     8221 tgtcatcatg ttgatcattt tgacagtatt ggctttactt tttggagtga aattctccaa
     8281 agcgcttgaa ggtggtatca aacttgccat cgctcttaca ggtatcggtg ctatcatcgg
     8341 tatgctaaat ggtgctttct cagcatcact tgcaaaattc gttgaaaaca ctggtatcca
     8401 attgagtatt acagacgttg gttgggcacc actcgcaaca atcacttggg gttctgcttg
     8461 gacactatac ttcttgctca tcatgttgat tgtcaacgta gtgatgcttg ctatgaagaa
     8521 aaccgataca cttgatgtcg atatctttga tatctggcac ttgtctatca caggtctctt
     8581 gattaaatgg tatgctgata acaatggtgt gagtcaaggg gtttcactct ttattgctac
     8641 agcagctatc gtccttgtcg gtgtgttgaa aattatcaac tctgacttga tgaaacctac
     8701 atttgatgac cttcttaacg ccccaagttc atcaccaatg acatcaactc acatgaacta
     8761 catgatgaac ccagttatca tggttttgga taagattttt gaaaaattct tcccaggcct
     8821 tgataaatat gactttgatg ctgctaaatt gaacaagaaa atcggtttct ggggatctaa
     8881 attcttcatc ggtttcatcc ttggtatcgt tatcggtatt atgggaactc cacatccaat
     8941 tgcaggtgtt gcagatgcag ataaatggcg tcttgttatc aaaggatggt tgtctcttgg
     9001 tttgactgcc ggtgtatctt tggaactctt ctcacttatc ggttcatggt tcatcgcagc
     9061 cgtagaacca ctatcacaag gtattacaaa cgttgctact aaacgtcttc gaggacgtaa
     9121 attcaatatc ggtcttgact ggccattcat cgctggtcgt gctgaaatct gggcttgtgc
     9181 caacgtactt gcaccaatca tgttgattga agcagtgctt ctttcaaaag ttggaaatgg
     9241 tatcttgcca cttgcaggta tcatcgctat gggtgttact ccagctctct tggttgtaac
     9301 tcgtggtaaa ttgctccgta tgattatctt cggaacactc ttgttgccac tcttccttct
     9361 ttcaggtaca cttattgcac catttgcaac agaacttgct aaaggtgtag gtgccttccc
     9421 agaaggtgtg agccaaactc aattgattac tcactctact cttgaaggac caatcgaaaa
     9481 acttcttggt tggacaattg gtaacactac aactggtgat atcaaagcaa tccttggtgc
     9541 agtagtcttc cttgtattct atatcggtat ctttgcttgg tacagaaaac aaatgatcaa
     9601 acgtaacgaa gagtacgcag caaaagcaaa ataatgcgct cctataaaat ataaactcaa
     9661 tgaaaatcaa agagcaaact aggaaactag ccgcaggttg ctaaaaacac agttttgagg
     9721 ttgtagataa gactgacgaa gtcagctcaa aacatggttt tgaggttgta gatgaaactg
     9781 acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa gtcagtaatc
     9841 atatctacgg caaggcgacg ctgacgaagt ttgaattgga ttttcgcaga gtgtaaattg
     9901 ttgaaactag gttgtcatac catgtatacc acttgggctt tggtagtagc taactgcact
     9961 aaatataata taaggagggt tttatgggga aaggccattg gaatcggaaa agagtttata
    10021 gcattcgtaa gtttgctgtg ggagcttgct cagtaatgat tgggacttgt gcagttctat
    10081 taggaggaaa tatagctgga gaatctgtag tttatgcgga tgaaacactt attactcata
    10141 ctgctgagaa acctaaagag gaaaaaatga tagtagaaga aaaggctgat aaagctttgg
    10201 aaactaaaaa tgtagttgaa aggacagaac aaagtgaacc tagttcaact gaggctattg
    10261 catctgagaa gaaagaagat gaagccgtaa ctccaaaaga ggaaaaagtg tctgctaaac
    10321 cggaagaaaa agctccaagg atagaatcac aagcttcaag tcaagaaaaa ccgctcaagg
    10381 aagatgctaa agctgtaaca aatgaagaaa tgaatcaaat gattgaagac aggaaagtgg
    10441 attttaatca aaattggcac tttaaactca atgcaaattc taaggaagcc attaaacctg
    10501 atgcagacgt atctacgtgg aaaaaattag atttaccgta tgactggagt atctttaaca
    10561 atttcgatca tgaatctcct gcacaaaatg aaggtggaca actcaacggt ggggaagctt
    10621 ggtatcgcaa gactttcaaa ctagatgaaa aagacctcaa gaaaaatgtt cgccttactt
    10681 ttgatggcgt ctacatggat tctcaagttt atgtcaatgg tcagttagtg gggcattatc
    10741 caaatggtta taaccagttc tcatatgata tcaccaaata ccttcacaaa gatggtcgtg
    10801 agaatgtgat tgctgtccat gcagtcaaca aacagccaag tagccgttgg tattcaggaa
    10861 gtggtatcta tcgtgatgtg actttacaag tgacagataa ggtgcatgtt gagaaaaatg
    10921 ggacaactat tttaacacca aaacttgaag aacaacaaca tggcaaggtt gaaactcatg
    10981 tgaccagcaa aatcgtcaat acggacgaca aagaccatga acttgtagcc gaatatcaaa
    11041 tcgttgaacg aggtggtcat gctgtaacag gcttagttcg tacagcgagt cgtaccttaa
    11101 aagcacatga atcaacaagc ctagatgcga ttttagaagt tgaaagacca aaactctgga
    11161 ccgttttaaa tgacaaacct gccttgtacg aattgattac gcgtgtttac cgtgacggtc
    11221 aattggttga tgctaagaag gatttgtttg gttaccgtta ctatcactgg actccaaatg
    11281 aaggtttctc tttgaatggt gaacgtatta aattccatgg agtatccttg caccacgacc
    11341 atggggcgct tggagcagaa gaaaactata aagcagaata tcgccgtctc aaacaaatga
    11401 aggagatggg agttaactct atccgtacaa cccacaaccc tgctagtgag caaaccttgc
    11461 aaatcgcagc agaactaggt ttactcgttc aggaagaggc ctttgatacg tggtatggtg
    11521 gcaagaaacc ttatgactat ggacgtttct ttgaaaaaga tgccactcac ccagaagctc
    11581 gaaaaggtga aaaatggtct gattttgacc tacgtaccat ggtcgaaaga ggcaaaaaca
    11641 accctgctat cttcatgtgg tcaattggta atgaaatagg tgaagctaat ggtgatgccc
    11701 actctttagc aactgttaaa cgtttggtca aggttatcaa ggatgttgat aagactcgct
    11761 atgttaccat gggagcagat aaattccgtt tcggcaatgg tagcggaggg catgagaaaa
    11821 ttgctgatga actcgatgct gttggattta actattctga agataattac aaagccctta
    11881 gagctaagca tccaaaatgg ttgatttacg gttcagaaac atcatcagca acccgtacac
    11941 gaggaagtta ctatcgccct gaacgtgaat tgaaacatag caatggacct gagcgtaatt
    12001 atgaacagtc agattatgga aatgatcgtg tgggttgggg gaaaacagca accgcttcat
    12061 ggacttttga ccgtgacaac gctggctatg ctggacagtt tatctggaca ggtacggact
    12121 atattggtga acctacacca tggcacaacc aaaatcaaac tcctgttaag agctcttact
    12181 ttggtatcgt agatacagcc ggcattccaa aacatgactt ctatctctac caaagccaat
    12241 gggtttctgt taagaagaaa ccgatggtac accttcttcc tcactggaac tgggaaaaca
    12301 aagaattagc atccaaagta gctgactcag aaggtaagat tccagttcgt gcttattcga
    12361 atgcttctag tgtagaattg ttcttgaatg gaaaatctct tggtcttaag actttcaata
    12421 aaaaacaaac cagcgatggg cggacttacc aagaaggtgc aaatgctaat gaactttatc
    12481 ttgaatggaa agttgcctat caaccaggta ccttggaagc aattgctcgt gatgaatctg
    12541 gcaaggaaat tgctcgagat aagattacga ctgctggtaa gccagcggca gttcgtctta
    12601 ttaaggaaga ccatgcgatt gcagcagatg gaaaagactt gacttacatc tactatgaaa
    12661 ttgttgacag ccaggggaat gtggttccaa ctgctaataa tctggttcgc ttccaattgc
    12721 atggccaagg tcaactggtc ggtgtagata acggagaaca agccagccgt gaacgctata
    12781 aggcgcaagc agatggttct tggattcgta aagcatttaa tggtaaaggt gttgccattg
    12841 tcaaatcaac tgaacaagca gggaaattca cccttactgc tcactctgat ctcttgaaat
    12901 ctagtcaagt cactgtcttt actggtaaga aagaaggaca agaaaagact gttttgggga
    12961 cagaggtgcc aaaagtacag accattattg gagaggcacc tgaaatgcct accactgttc
    13021 cgtttctata cagtgatggt agtcgtgcag aacgtcctgt aacctggtct tcagtagatg
    13081 tgagcaagcc tggtattgta acggtgaaag gtatggctga cggacgagaa gtagaagctc
    13141 gtgtagaagt gattgctctt aaatcagagc taccagttgt gaaacgtatt gctccaaata
    13201 ctgacttgaa ttctgtagac aaatctgttt cctatgtttt gactgatgga agtgtacaag
    13261 agtacgaagt agatagctgg gagattacgg aagtagataa agccaaactt tcagtagctg
    13321 gatcacgtat tcaaatgact ggtcagttag ctggagaaac tattcatgca acccttgtgg
    13381 tagaagaagg aaatgctgca gcacctgtag tgccaactgt tactgttgga ggtgaagcag
    13441 taacaggtct tactagtcga caaccaatgc aatatcgtac tctatcttat ggtgcccaat
    13501 tgccagaagt cacagcaagt gctgaaaatg ctgatgtgac agttcttcaa gcaagcgcag
    13561 caaacggcat gcgtgcaagc atatttgttc agcctaaaga tggtggccct cttcaaacct
    13621 atgcaattca attcctagaa gaagcaccaa aaattgctca cttgagcttg caagtggaaa
    13681 aagctgacag tctcaaagaa gaccaaactg tcaaattgtc ggttcgagct cactatcaag
    13741 atggaacgca agctgtatta ccagctgata aagtaacctt ctctacaagt ggtgaagggg
    13801 aagtcgcaat tcgtaaagga atgcttgagt tgcataagcc aggagcagtc actctcaaag
    13861 cggaatatga gggagctaaa ggccaagttg aactcactat ccaagccaat actgagaaga
    13921 agattgcgca atctatccgt cctgtaaatg tagtcacaga tttgcatcaa aaacctactc
    13981 ttccaacaac agtaacggtt gagtatgaca aaggtttccc taaagctcac aaagtcactt
    14041 ggcaagctat tccgaaagaa aaactagact cctatcaaac atttgaagta ctaggtaaag
    14101 ttgaaggaat tgaccttgaa gcgcgtgcaa aagtctctgt agaaggtatc gtttcagttg
    14161 aagaagtcag tgtgacaact ccaatcgcag aagcaccaca attaccagaa agtgttcgga
    14221 catatgattc aaatggtcac gtttcatcag ctaaggttgc atgggatgcg attcgtccag
    14281 agcaatacgc taaggaaggt gtctttacag ttaatggtcg cttagaaggt actcaattaa
    14341 caactaaact tcatgttcgc gtatctgctc aaactgagca aggtgcaaac atttctgacc
    14401 aatggaccgg ttcagaattg ccacttgcct ttgcttcaga ctcaaatcca agcgacccag
    14461 tttcaaatgt taatgacaag ctcatttcct acaataacca accagccaat cgttggacaa
    14521 actggaatcg tactaatcca gaagcttcag tcggtgtcct attcggagat tcaggtattt
    14581 tgagcaaacg ttcagttgat aacttaagcg ttggcttcca tgaagaccat ggagttggtg
    14641 caccgaagtc ttatgtgatt gagtattatg ttggtaagac tgtcccaaca gctcctaaaa
    14701 accctagttt tgttggtaat gaggaccatg tctttaatga ttctgccaac tggaaaccag
    14761 ttactaatct aaaagcccct gctcaactca aggctggaga aatgaaccac tttagctttg
    14821 ataaagttga aacctatgct gttcgtattc gcatggtgag agcagacaac aaactaggaa
    14881 cgtctatcac agaggtacaa atctttgcga aacaagttgc ggcagccaag caaggacaaa
    14941 caagaatcca agttgacggt aaagacttag caaacttcaa ccctgatttg acagactact
    15001 accttgagtc tgtagatgga aaagttacgg cagtcacagc aagtgttagc aacaatggcc
    15061 tcgctaccgt cgttccaagc gttcgtgaag gtgagccggt tcgtgtcatc gcgaaagctg
    15121 aaaatggcga catcttagga gaataccgtc tgcacttcac taaggataag aacttacttt
    15181 ctcataaacc agttgctgcg gttaaacaag ctcgcttgct acaagtaggt caagcacttg
    15241 aattgccgac taaggttcca gtttacttca caggtaaaga cggctacgaa acaaaaaacc
    15301 tgacagttga atgggaagaa gttccagcgg aaaatctgat aaaagcaggt caatttaccg
    15361 ttcgaggcca tgtccttggt agtgatcttg ttgctgaggt cactgtacga gtgacagaca
    15421 aactaggcga agctctttca gataacccta actatgatga aaacagtaac caggcctttg
    15481 cttcagcaac caatgatatt gacaaaaact ctcatgaccg cgttgactat ctcaatgacg
    15541 gagatcattc agaaaatcgt cgttggacaa actggtctcc aacaccatct tctaatccag
    15601 aagtatcagc gggtgtgatc ttccgtgaaa atggtaagat tgtagaacgg actgttgctc
    15661 aagccaaact tcacttcttt gcagatagtg gtacggatgc accaactaaa ctcgttttag
    15721 aacgctatgt cggtccagag tttgaagtgc caacctacta ttcaaactac caagcctacg
    15781 acgcagacca tccattcaac aatccagaaa attgggaagc tgtgccttat cgtgcggata
    15841 aagacatcgc agctggtgat gaaatcaacg taacatttaa agctgtcaaa gccaaagcta
    15901 tgagatggcg tatggagcgt aaagcagata agagcggtgt tgcgatgatt gagatgacct
    15961 tccttgcacc aagtgaattg cctcaagaaa gcacgcaatc gaagattctt gtagatggaa
    16021 aagaacttgc tgatttcgct gaaaatcgtc aagactatca aattacctat aaaggtcaac
    16081 ggccaaaagt ctcagttgaa gaaaacaatc aagtagcttc aactgtggta gatagtggag
    16141 aagatagcct tccagtactt gttcgcctcg tttcagaaag tggaaaacaa gtcaaggaat
    16201 accgtatcca gttgactaag gaaaaaccag tttctgagaa gacagttgct gctgtacaag
    16261 aagatcttcc aaaactcgaa tttgttgaaa aagatttggc ctacaagaca gttgagaaaa
    16321 aagattcaac actgtatcta ggtgaaactc gtgtagaaca agaaggaaaa actggtaaag
    16381 aacgtatctt tacagcgatt aatcctgatg gaagtaagga agaaaaactc cgtgaagtgg
    16441 tagaagctcc gacagaccgc atcgtcttgg ttggaaccaa accagtagct caagaagcta
    16501 aaaaaccaca agtgtcagaa aaagcagata caaaaccaat tgattcaagt gaagctagtc
    16561 aaactaataa agcccagtta ccaaatacag gtagtgcggc aagccaagca gcagtagcag
    16621 caggtttagc tcttctaggt ttgagtgcag gattagtagt tactaaaggt aaaaaagaag
    16681 actagaaatt ttgatacctt ctttatcatt aaagaccaaa gaaaaactct tgtcctaaat
    16741 agaagataaa gagtctggaa caaaatagtt ctcaaccaca aaaaagctag atatttccaa
    16801 ttgcggaact ctagcttttt aattttgagt cgttctctta ttgtatagta gattgaaact
    16861 agagtagtac acttctactt ctaaaacatt gttagaaatc gatttgactg tccttatcga
    16921 tttgtcctgt tcttatttca tttcactatg ttttaggagg ttattggcca taagtaccaa
    16981 tcccatgtca attctcactt gacgcttgcc tctcagatta catctcttgt aacccaaaca
    17041 agcctttatc tgcccaaaga caggttctac atcaatcttg cgttgagcga aaatctgtct
    17101 atcttgggga gataaaagcg cctgacattc tttagctttc aagttttgat agcgttcgtt
    17161 catatacaat cccttttgag gggctgattc aggttcatca gcgtagtaaa ccttgatttc
    17221 ctgttgaaag tctgtctgtg ttttctggta cttgatatgg tgaaaacgat agcaccagcc
    17281 atcaggatgt atgtagctat cctccttgtc attatagtgc caattcgcta agtttttagc
    17341 tgactgttta taccctctct tttgttcctt atcaaacatg gcatatttaa tcagaagggg
    17401 agtgatttct tcttgaaaat agacttgtat ctgttcttga agtttggcgg agaatttctc
    17461 tgtcgttttc ttccacacaa aactatactt gttggcattg gattcaatct tagttccgtc
    17521 aataaacaaa caatctaagg tcactaactc ttccattttt caatttttcg accagagaaa
    17581 atcccttgtg aataggcaaa tagaagagta gatacaagca ttttagggtg ataagacggg
    17641 cgaccaaagg catgatagga ggtgtagaag tgacgttcct ccaaggtatt caccactttt
    17701 tcaatagtaa agacgagatg gtcttgtggt aagaaggaac tgatttctag tggtaaagtt
    17761 gtttgatttg tgttatagtg aatatgcatg ggatagcctt tctaaatggt ttattaagca
    17821 attctatttt accaagacta tcgtaaccat gcaaaaaagc aacggcaaat ccgttgcctt
    17881 ttttggatat aagagactat tgtcccagac tcttttcttt gtataaaatt gtatagtgtt
    17941 attgtctata ctattttgta gagaaagcaa aaatccctag aaaatgctta gggattcgac
    18001 tatttcatta agaacaattc aacaatcatc tctatataca tgataagggt taataaaaat
    18061 cctgtacgcc agaagaattt gatgaattta ggatagtaaa agctgcgttt ttttaaaagg
    18121 aagaaaaaga cgagaataat ggctaggaac gagagggcta gccccagtct agggaggaaa
    18181 ttatgggtaa aggttttagc tgtaatcaag taatactcaa ataccaagac tggaaaagcc
    18241 aaatccgcaa agtttcgtcc tagttttttt aatctaaaaa gtttggttag gataatgcag
    18301 acgactaagg tcagtatcaa taataaaata gatgctaatt tcattaaaat catacccata
    18361 ttgtatcata aaaaaaggct aatggaaacg agaaacagag gaatttatag gaaagtcagg
    18421 cttttgagat tgtgggtgat ttttgttata atgaaagtta taaaatctta tgataccttg
    18481 aatgattatt atcgaaaact ctttggagaa aagactttta aagtccctat tgatgcggga
    18541 tttgactgtc ccaatcgtga tggaactgtg gctcatggag gctgtacttt ttgtacggtt
    18601 tccggttctg gagatgccat tgtagcccca gatccgccta tccgtgagca attttataag
    18661 gaaattgact ttattcatcg taagtggcca gatgttcaga agtatctggt ttattttcaa
    18721 aattttacca acacccatga aaaggtggaa gttattcgag agcgttatga acaggctatc
    18781 aatgagccag gtgtggtagg aatcaatatt ggaacgcgcc cagactgttt accagacgaa
    18841 accatcgaat atttggctga gttatcggag tgcatgcatg tgacggttga attgggcttg
    18901 cagactactt atgaagcaac ctctgacctg attaaccgtg cgcattctta tgaattgtag
    18961 gtggaaacgg tcaagcgttt gagaaagtat ccaaaaattg agattgtttc ccatttgatc
    19021 aatggtttgc ctggtgaaac ccatgagatg atggttgaaa atgtccgccg ttgtgtcacg
    19081 gataacgata ttcaagggat taaactgcat ttgctccatc ttatgacaaa tactcgtatg
    19141 caacgagatt accatgaggg acgtttacaa ttgatgagtc aggacgaata tgtcagggtc
    19201 atctgtgacc aactggaaat tattcccaaa catatcgtca tccatcgaat tacaggagat
    19261 gcgcctaggg atatgctgat tggtcctatg tggagcctca ataaatggga agtcctcaac
    19321 agcattgaga tggagatgag acgtcgtgga agtgttcaag gatgcaaggc tgtaaaacag
    19381 gagtttgaaa atgaaaagac cacttgagat ggcacatgat tttttggctg aggtcgtgac
    19441 aaaagaggat gtcgtagtgg atgcgactat gggaaatggt catgacacgc tttttttagc
    19501 caagctagcc aagcaagtct atgcctttga tattcagaag caagccttgg aaaagaccca
    19561 agagcgtttg catcaggctg gcttgacaaa tgcccagtta atcttgcaag gccatgagac
    19621 actggaccag tttgtgacaa aagctaaggc agggattttt aatttgggct atttgccgtc
    19681 agctgataag tctgtcatca cccgaccgca gacaacgatt gaggcattag aaaagctatg
    19741 tggcttactt gtcaaaggtg gacgaattgc tattatgatt tactatggtc atgaaggagg
    19801 cgacctcgag agagatgctg tcttggattt tgtgatccag ttgaaccaac aagagtacac
    19861 agctgccatt taccgaactt taaaccaagt caacaacccg ccgtttttag tgatgattga
    19921 aaaattagag agatacagac atggataaac aatacctaca cgaaaagctg gatgccatgc
    19981 gccagaattt tgttgaatca acctaccacg aacgagcggt gggcgtgcta gaccaagcgc
    20041 atatgagcaa aaaaatgctt aaaatcaaga aaaaattagt tgctcttgaa atggaacggt
    20101 gccagagaaa aattgagcac aaagactgtt ccaagattga ccaaaaaatc aaagagcaga
    20161 aggagatatt tgaatcctgt tgtaaaaaag attaaggagg acgtgcgtgg aattactgat
    20221 ttacctcatc ctatttttac tggtcttgat tgtctcaagt acaaccaata agctcctacc
    20281 ctttttgcct ctccctttgg tgcagattct tttgggaatt gtgattggtc tctttttacc
    20341 caatactgac tttcacctta atacggagtt gtttttggca ctggttatcg gccccttgct
    20401 tttccgagag gctgaagaag cagatgttac ggctatttta aaacactggc gaatcattgt
    20461 ttatctcata tttccagtga tttttatctc gaccctgagt ttgggtggct tggcccatct
    20521 tctttggttc agccttccct tggcagcttg cttggctgtt ggggcagccc ttggtcctac
    20581 ggacttggtg gcctttgcct ctctttcgga gcgttttagc tttcctaagc gcgtgtccaa
    20641 tattcttaag ggcgaaggac tcttgaatga tgcttctggt ttggtggctt ttcaggtagc
    20701 tttgacagct tggacaactg gagctttttc tctggggcaa gctagcagtt cactcatctt
    20761 ttcaatccta ggcggttttt taattggatt tttaacagcc atgaccaacc gcttcctcca
    20821 taccttcttg ctaagtgtgc gtgcaacgga tattgccagt gaacttttat tagaattgag
    20881 tttgcctctt gtgaccttct ttctggcaga agaagttcat gtttcaggta ttattgccgt
    20941 cgtagttgct ggaattttaa aggcaagtcg tttcaagaaa atcacgctcc tcgaagccca
    21001 agtggatacg gtgaccgaga cggtctggca tacagtgacc tttatgctca acggttctgt
    21061 ctttgtgatt ttagggatgg agctggaaat gatagcagaa cctatcttga ccaatccaat
    21121 ctataatcct ctacttttat tgctatctct tatcgccctt acctttgtcc tctttgtcat
    21181 tcgttttatt atgatctatg gctattatgc ctatagaacc cgacgcctca agaaaaagct
    21241 aaataagtat atgaaggaca tgtttctctt gaccttttca ggtgttaagg gaacggtgtc
    21301 gattgctacg attctcttga taccaagtaa tctagaacag gagtatcctc tcttgctttt
    21361 ccttgttgca ggtgtgacgc ttgttagctt tttaacaggt ctcttggtct tgcctcatct
    21421 ttctgatgaa gaggaagaaa gcaaggatta tctcatgcat atcgccattt tgaatgaagt
    21481 aacgctagag ttggaaaaag agttggaaga caccagaaat aaactttccc tctatgcggc
    21541 tattgacaat tatcatggac gtattgaaaa tctcatttta agccaagaaa accaggatga
    21601 tcaagaagac tgggctgctt tgaaactctt gattcttagt attgaaagtg atggtttgga
    21661 acaggcctat gaagagggga atattagcaa tcgtgcttac cgagtttacc aacgttatct
    21721 gaaaaatata gaacaaggaa tcaatcgtaa acttgcctca agactgacct attattttct
    21781 tgtttccttg aggattttac gttttctcct tcatgaagtt tttactcttg gaaagacctt
    21841 ccgtagctgg aaggacaagg agcaaagccg tctccgtgct cttgattatg accaaattgc
    21901 agagctctat cttgccaata cagagatgat tattgaaagt ttggaaaacc tgaagggagt
    21961 ctacagacgc tctttgatta gttttatgca ggagtctcgt cttcgagaaa cagctattat
    22021 cagcagtggt gcctttgtcg aacgggttat caatcgtgtc aaacccaaca atatcgatga
    22081 aatgctgaga ggctattatc tggagcgcaa gttgattttc gaatacgaag aaaaacgatt
    22141 aattacaact aagtatgcca agaaattacg acaaaatgta aataacttag agaactattc
    22201 cttgaaggaa gctgccaata ccctgccgta tgatatggtg gaattggtaa gaagaaatta
    22261 gttaatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttggat tatatatgtg
    22321 actgacttcg tcagtttcat ctacaacctc aaagcagggc tttgagcaac ctgcggctag
    22381 cttcctagtt tgctctttga ttttcattga gtataagatt ataaatgaag gagtatgaca
    22441 tgaaaaagtg gtggaaagag ctgatagaca agcctttatt aaaagctttt ttgcattatt
    22501 atcaagcatc agatagtgag ttgaccagtg tcgcagtagc ctactattgg ttgatttcga
    22561 ttttccccct gcttttggtg gtggtcaata tcctccccta ttttcagatt cctgtgggag
    22621 aatttctgtg ctttatgaaa gacgttctgc ccccaagcct ctatgaaggt gtggaaaaaa
    22681 tagccagaga agttttgacg caaccttcaa caggtttatt gagtttttct gttttatcgg
    22741 cgttatggag tttttcaaaa tctatgaatt tcttgcaaaa agcttttaac aaggcttatg
    22801 gcgtcgaaaa gagtcgtgga cttatttccc atcagatgct aagtctccta gtcagttttg
    22861 gcttgcagct cctctttgcg tttgccttgt ttttgatctt atttggtcag atgattttgg
    22921 ctttacttgc tcattattgg acaaaagatg gcattatcta tcaggcttta caagggttgg
    22981 caggtcctct gatttacgcc ctcctctttg ctatcttggt catgctttat tattttcttc
    23041 ccaatatatc taacaggaaa attagctata ccctaccagg cagtgccttt gttctcttag
    23101 tgattttagg tttactaact ctgttctcta gttatctcaa ttactatgtc catcatttgg
    23161 tggatgtccg aattttaggt tccgttcttc ttgttgttat gatgttttgg tttatcttga
    23221 ttgctaaaat tgttatccta ggcgcggtta tcaatgccag tatgcagagt ttgagagatc
    23281 cggtctttaa aaaagactaa ctatttatcc attacaaaag cgcatagtat caaaacttta
    23341 tagaaccttg atactatgcg cttttgtgct ttgacagttt tttgtatagt ttttgtccaa
    23401 gatttctaaa tcatctgatt aaattcctat tttcccctat cattgtccct gttttttcga
    23461 aaatggaagg agtataataa atctatcaat aaaatgatag gaggaacttt atgggtcata
    23521 ttttcttttt tctaagtgtc tttttggcag ggattctatc cttcttttct ccttgtatct
    23581 tacctttgtt accggtctat acaggagtgt tactagatga taaggatggt gctcaggctt
    23641 ctagcggcaa attttcaatc tcagttacta gtttattacg aactctggcc tttatagcag
    23701 gaatttcctt tatatttatt ttgttgggct atggagctgg ttttttaggc gatttgcttt
    23761 atgcttcttg gttccaatat cttactgggg caattattat ccttcttggt ttgcaccaaa
    23821 tggagattct acactttaag gggctttata aggaaaagag gctacaactg caaggacagg
    23881 ggcaaaatgg taagggctat agtcaggcat ttttattggg cttgaccttt agttttgctt
    23941 ggacgccttg cgtggggccg gttctggggt ctgttttggc cttggcggct tcaggtggtt
    24001 caggagcttg gcagggagct ggtctcatgt tggtgtatac gctgggcttg gcgctaccat
    24061 tcttgcttct agctctgacc tctagttatg ttttgaaaca tttccgaaaa cttcatccct
    24121 atctcggaat cctcaaaaaa gtgggtggtt ttctcattat tgtgatggga ctcttggttc
    24181 tgtttggaaa tgcttcaatt ttaagtcaat tatttgaata aaatggaaag gaatatcaat
    24241 atgaaaaaat ggcaaacatg tgttcttgga gcaggttcgc tcctttgttt gacggcttgt
    24301 tcaggcaagt ccgtgactag tgaacaccaa acgaaagatg aaatgaagac ggagcagaca
    24361 gctagtaaaa caagcgcagc taaagggaaa gaggtggctg attttgaatt gatgggagta
    24421 gatggcaaga cctaccgttt atctgattac aagggcaaga aagtctatct caaattctgg
    24481 gcttcttggt gttccatctg tctggctagt cttccagata cggatgagat tgctaaagaa
    24541 gctggtgatg actatgtggt cttgacagta gtgtcaccag gacataaggg agagcaatct
    24601 gaagcggact ttaagaattg gtataaggga ttggattata aaaatctccc agtcctagtt
    24661 gacccatcag gcaaactttt ggaaacttat ggtgtccgtt cttacccaac ccaagccttt
    24721 atagacaaag aaggcaagct ggtcaaaaca catccaggat tcatggaaaa agatgcaatt
    24781 ttgcaaactt tgaaggaatt agcctaggag gtgtcttatg aatgataagt taaaaatctt
    24841 cttgttgcta ggagtatttt ttctagccat aaccggtttc tatgttctat tgatacgaaa
    24901 tgcagggcag acagatgcct cgcaaattga aaaggcggca gttagccaag gaggaaaagc
    24961 agtgaaaaaa acagaaatta gtgaagacgc agacttgcac gaaatttatc tagctggagg
    25021 ttgtttctgg ggagtggagg aatatttctc acgcgttccc ggggtgacgg atgccgtttc
    25081 aggctatgca aatggtagag gagaaacaac caagtacgaa ttaattaacc aaacaggtca
    25141 tgcagaaacc gtccatgtca cctatgatgc caagcaaatt tctctcaagg aaatcctgct
    25201 tcactatttc cgcattatca atccaaccag caaaaataaa caaggaaatg atgtggggac
    25261 ccagtaccgt actggtgttt attacacaga tgacaaggat ttggaagtga ttaaccaagt
    25321 ctttgatgag gtggctaaga aatacgatca acctctagca gttgaaaagg aaaacttgaa
    25381 gaattttgtg gtggctgagg attaccatca agactatctc aagaaaaatc caaatggtta
    25441 ctgccatatc aatgttaatc aggcggccta tcctgtcatt gatgccagca aatatccaaa
    25501 accaagtgat gaggaattga aaaagaccct gtcacctgag gagtatgcag ttacccagga
    25561 aaatcaaaca gaacgagctt tctcaaaccg ttactgggat aaatttgaat ccggtatcta
    25621 tgtggatata gcaactgggg aacctctctt ttcatcaaaa gacaaatttg agtctggttg
    25681 tggctggcct agttttaccc aacccatcag tccagatgtt gtcacctaca aggaagataa
    25741 gtcctacaat atgacgcgta tggaagtgcg gagccgagta ggagattctc accttgggca
    25801 tgtctttacg gatggtccac aggacaaggg cggcttacgt tactgtatca atagcctctc
    25861 tatccgcttt attcccaaag accaaatgga agaaaaaggc tacgcttatt tactagatta
    25921 tgttgattaa tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    25981 agggttactg acttcgtcag ttttatctac aacctcaaag ctatactttg agctgacttc
    26041 gtcagtttta tctacaacct caaagcggta ctttgagaaa cctgtggcta tcttcctagt
    26101 ttactttttg atttttattg agtataagag gtctttccta agcagttaga ggagaatttt
    26161 gctatactga tactagtaag tggtaaagga gcagagcatg acctacacaa tcttaatcgt
    26221 agaagatgaa tatctggtaa gacaaggttt gactaaactg gtcaatgtag cagcctacga
    26281 tatggaaatc atcggtcagg ctgaaaatgg aaggcaggct tgggaattga tccaaaagca
    26341 ggtgccagat atcattttaa ccgatatcaa catgcctcat ctaaatggca tccagttggc
    26401 cagtctggta cgagaaacct atcctcaggt tcatttggtc tttttaacag gttacgatga
    26461 ttttgattat gccttgtctg ctgtcaaact aggtgtggac gactacctgc tcaaaccctt
    26521 ttctcgtcag gatattgagg aaatgttggg gaaaatcaaa caaaaactag acaaggaaga
    26581 gaaagaagag cagttacaag atttattgac taataggttt gaaggaaaca tggcccagaa
    26641 aatccagtct catctggctg atagccaatt tagtttaaag tctttagcca gtgacttagg
    26701 ttttagtccg acctatctga gttccttgat taagaaagag ttgggcttgc cttttcagga
    26761 ttatctggtg agagaacgtg ttaaacaagc caagctcttg cttttaacta cagatctgaa
    26821 gatttatgag atcgcagaga aggttggttt tgaagatatg aactatttta cccaacgttt
    26881 taagcagatt gcaggtgtga cacctcgtca gtttaagaag ggagaagacc gatgaagcgt
    26941 tcttctcttt tagttagaat ggttatttcc atctttctgg tctttctcat tctcctagct
    27001 ctggttggaa ctttctacta tcaatcaagt tcttcagcca ttgaggccac cattgagggc
    27061 aacagccaaa cgaccatcag ccagactagc cactttattc agtcttatat caaaaaacta
    27121 gaaaccacct cgactggttt gacccagcag acggatgttc tggcctatgc tgagaatccc
    27181 agtcaagaca aggtcgaggg aatccgagat ttgtttttga ccatcttgaa gtcagataag
    27241 gacttgaaaa ctgttgtgct ggtgaccaaa tctggtcagg tcatttctac agatgacagt
    27301 gtgcagatga aaacttcctc tgatatgatg gctgaggatt ggtaccaaaa ggccattcat
    27361 cagggagcta tgcctgtttt gactccagct cgtaaatcag atagtcagtg ggtcatttct
    27421 gtcactcaag aacttgttga tgcaaaggga gccaatcttg gtgtgcttcg tttggatatt
    27481 tcttatgaaa ctctggaagc ctatctcaat caactccagt tggggcagca gggctttgcc
    27541 ttcattatca atgaaaacca tgaatttgtc taccatcctc aacacacagt ttatagttcg
    27601 tctagcaaaa tggaggctat gaaaccctac atcgatacag gtcagggtta tactcctggt
    27661 cacaaatcct acgtcagtca agagaagatt gcaggaactg attggacggt gcttggcgtg
    27721 tcatcattgg aaaagttaga ccaggttcgg agtcagctct tgtggacctt gcttggggcc
    27781 agtgtcacat ctcttcttgt ctgtctctgc ttagtgtggt tcagtcttaa acgctggatt
    27841 gctcctttga aggatttgag agaaaccatg ttggaaattg cttctggtgc tcaaaatctt
    27901 cgtgccaagg aagttggtgc ctatgaactg agagaagtaa ctcgccaatt taatgctatg
    27961 ttggatcaga ttgatcagtt gatggtagct attcgtagcc aggaagaaac gacccgtcag
    28021 taccaacttc aagccctttc gagccagatt aatccacatt tcctctataa cactttggac
    28081 accatcatct ggatggctga atttcatgat agtcagcgag tggtgcaggt gaccaagtcc
    28141 ttggcaacct atttccgctt ggcgctcaat caaggcaagg acttgatttg tctctctgac
    28201 gaaatcaatc atgtccgcca gtatctcttt atccagaaac aacgctatgg agataagctg
    28261 gaatacgaaa ttaatgaaaa tgttgccttt gataatttag tcttacccaa gctggtccta
    28321 caaccccttg tagaaaatgc tctttaccat ggcattaagg aaaaggaagg tcagggccat
    28381 attaaacttt ctgtccagaa acaggattcg ggattggtca tccgtattga ggatgatggc
    28441 gttggcttcc aagatgctgg tgatagtagt caaagtcaac tcaaacgtgg gggagttggt
    28501 cttcaaaatg tcgatcaacg gctcaaactt cattttggag ccaattacca tatgaagatt
    28561 gattctagac cccaaaaagg gacgaaagtt gaaatatata taaatagaat agaaactagc
    28621 taactcccag tcaattctgg gagttttatg cgtaattggg caaactttct aggttgtcta
    28681 tcttgctaaa aacaagaaaa aacggtatga tagaagagtg acaacagagg taacagagat
    28741 gaacgagaca cagattcaaa gagaaacacg tcaggtagtg gaagatgttt tagaaaagac
    28801 caatttgaag cagggggccc tttttgtttt aggtctatct tctagtgagg tgctaggtgg
    28861 tcatattggg aaagaatcca gtcaagagat tggtgagctg atagtggaga ctatcttgga
    28921 tattctaggt agtagaggta tccatttagc agttcaaggt tgtgagcatg tcaatcgggc
    28981 tctcgttgtt gaacgtcagg tggcagagca gtttggtctg gaaattgtca gtgtccatcc
    29041 tactcttcat gcaggaggtt cggggcagtt ggcagccttt aagtttatgc aggatccagt
    29101 tgaggttgaa tttatcaagg ctcatgctgg attggatatc ggagacactg caattggcat
    29161 gcatgtcaag catgttcagg ttccgattcg ccctattttg agagagattg gtcatgccca
    29221 tgtaacggca ctggctagtc gtccaaaatt aatcggaggt gcgcgtgcgc actatccgca
    29281 agatgctatt agaaagacct gagaatgaat aaaggagata aaagtgttta aaaaagaccg
    29341 tttttcaatt cgtaagatta agggagttgt aggctctgta tttcttggaa gccttttgat
    29401 ggctccttct gtagtggacg cagccaccta tcactatgta aataaagaga ttatttcaca
    29461 agaagctaaa gatttaattc agacaggaaa gcctgacagg aatgaagttg tatatggttt
    29521 ggtgtatcaa aaagatcagt tgcctcaaac agggacagaa gcatctgttt tgacagcttt
    29581 tggttatcta tcaggtgaca tcctcaaaac gcttggcttg gacactgttt tagaagaaac
    29641 ctcagcaaaa cctggagagg tgactgtagt cgaagttgag actcctcaat caacaacaaa
    29701 tcaggagcaa gctaggacag aaaaccaagt agtagagaca gaggaagctc taaaagaaga
    29761 agcacctaaa acagaagaaa gtccaaagga agaaccaaaa tcggagataa aacctactga
    29821 cgacaccctt cctaaagtag aagaggggaa agaagattca gcagaaccag ctccagttga
    29881 agaagtaggt ggagaagttg agtcaaaacc agaggaaaaa gtagcagtta agccagaaag
    29941 tcaaccatca gacaaaccaa cagaggaacc aaaagttgaa caagtaggtg aaccagtcga
    30001 gccaagtgaa gacgaacagg caccaacggc accagttgag ccagaaaagc aaccagaagc
    30061 tcctgaagaa gagaaggctg tagaggaaac accgaaacca gaagataaaa taaagggtat
    30121 tggtactaaa gaaccagttg ataaaagtga gttaaataat caaattgata aagctagttc
    30181 agtttctcct actgattatt ctacagcaag ttacaatgat cttggacctg ttttagaaac
    30241 tgcaaaaggt gtctatgctt cagagcctgt aaaacagcct gaggtaaata gtgagacaaa
    30301 taaacttaaa acggctattg acgctctaaa cgttgataaa actgaattaa acaatacgat
    30361 tgcagatgca aaaacaaagg taaaagaaca ttacagtgat agaagttggc aaaacctcca
    30421 aactggggtt acagaagctg aaaaagttgc agctaataca gatgctaaac aaagtgaagt
    30481 aaattctgag actgcaagtc ttaaaacagc aatttctaga ttaaatacag ataaagttga
    30541 actcgaaaat caacttaaga ttgcacaggg aaaaactgaa actgatttca gcatggaatc
    30601 ttggactgtt ttgagtacag ctaaaaataa agctcaggaa gtaaaagata acggaacagc
    30661 gacccaagaa caaataaacg aagcagagaa aagtttgaaa acagcccttg ctgacttatc
    30721 tgttgacaaa acagctttgg gaagcgctat cgatacagct actaagaaaa ataaagagaa
    30781 ttatacaaat caaacatggg cagagttgga aacagcgctt acagcagcaa aatctgtaaa
    30841 tactaacgag tctaaacaaa gcgacgttaa cgaagctgct gaaaaattaa ctgcaactat
    30901 ggaaaaattg gttgaattgt ctgaaaagcc acgtttgact ctatctattg aaaagagaga
    30961 catagatcga aaagctacgg tcacgtatac tttggaaaat ccagcaaata ctcaaataaa
    31021 atcaataact gcaactctga aaaaaggaga ggaagttgtt aaggattttg ttttaacaga
    31081 agaaaatctt aaaactaatc atttaactgc tttgtttgaa aagctagact actacaaaga
    31141 atacactcta tctacggata tggtatataa cagaggaaat gatgatgaga cggagagtat
    31201 ttcagaagaa ctaattcagc tgaatcttaa gaaactagaa ttgaaagata tccagacagt
    31261 ctctctgatg aaatttgaaa atggtcaaga aagtcaggtt acacacttgt ctgataaacc
    31321 gaccgatttg agtaaattat acttaaaagt tacatcatca acgtctaagg atgctgtgtt
    31381 agccgttagc tctatagaag aagagattat tgaaaataaa aaaatcttta aaattcatgc
    31441 agatacacca gaattagtag ttcgtaagaa agatggcagt ctttctaagg gatttgacta
    31501 ttacatggag agagttatcc ctcatgatgg tgatatttat tatgatttta aagacttgat
    31561 ttcagctatg acatctaatc ctacaggtac gtttatttta gggagagata tttcctcgcg
    31621 taatgtaaaa ccggatggaa atggaaaatc ttatatcaaa ggtgaattta aaggaaaact
    31681 acttggtaca aatgataatg ttagacactc gatctttgac ttagaatatc cattgtttga
    31741 tactataaaa tcaggagtcg tgaaagatat tgatttcaag catgtcaata tggtattccc
    31801 agatagcaat caaggagata acgtagcaac aattgcaaga gtaatcaaag ataagacaaa
    31861 aattgagaat gttaatgttg aaggttatct cgagggtcga gatcatgtag ctggtttagt
    31921 taataatctt gaaggtaatt ccgaaattga aaatgtatcc tttacaggaa agattaagtc
    31981 taaaggtggt aattctatta cagcaggtat tgcaggtaga aatatcttat ctcgtgttaa
    32041 acgtgcctat gtaaatgcag atatagaggt acatcgatca tctaattcta gcatgcttgt
    32101 tgcagtaaat ggaataaacg cagatgcaag tggtggttgg ggaacctggg gtagacttac
    32161 tgagtcagtt gctaaaggaa cattagaaac caagcaagga gggcaagctg gaggagcctc
    32221 ttctacagtc tggccttatg gagcaattga taatgttgtc agctatgcaa aagtgaccaa
    32281 agggaaagaa ttatttggat cagatggtga tttaaattat gattggttta tgaaaaaaat
    32341 tagtaatatt tttggtgttc aaggcatcag ctcaggcgat tcgggtagtg attctaaatt
    32401 tacgcgtatt tctgaggaag aagcaaatca aaaagttgct tcttataata ttacagctcc
    32461 caacttgatg agtgactcaa gtcttttggt agacagactc aatgaaagtt ggaaaaatac
    32521 tgatcaattt gaaagtatac aggattatca agcccaaaac caattaattt accagaactt
    32581 gactaaattt actccttatt acaataaaga atttattgtt catgaaggaa atgctctcac
    32641 tcctgaacag gaaatattga agactaagaa aatcaaatcg attgtagggt tgaaaggaac
    32701 agagttcgtt gtagatggca gtgatattga tactatcatg cttcattttg aggatggtag
    32761 tcagaagcga tataaggtaa cctctactgg taagttttcg ataactaatt taccggaata
    32821 tcaggttgaa gatttaaatg tggtgtatac atcagaacat atagtacatc cactagattc
    32881 gtcactgata aataaccttg ttgaagaatt gaaaaaagta gaattgtata cagagtctac
    32941 ttaccaagtt ctaggtattg ataaagataa tgctaacaaa ttgaatagaa ctaagagatt
    33001 attcttagat gagtcattag atgctgttaa aacacaattg cctacctttg taaaaacaat
    33061 gtttgaaaat gagtggttgc acatcaatgg agaatctagt ggagctgtcg ctgctttacg
    33121 acaaaaaatc atggataata agacggctat attgcttgct ttgacttata tcaatcgtta
    33181 ttatgatgtt aaattctcag actataatat taaaaaactg atgctcttta aaccaacttt
    33241 ccatggtgaa aagattgatc tattagatcg attaatccga ctaggatcat ctggagaaaa
    33301 tagattaaaa ggttcagaaa atgcagaaac gttcaagcag ttatttgcta gcgaaacgaa
    33361 gcagaaggat ttggtgactt atttagacta caatcgctct ttgttgacta attatcaaac
    33421 aacaggggaa tggtttaaag aaacgactaa ggattatatt caatttgagg aacgtccatc
    33481 cttagtagag gagattaaag atgccaaata tcgagtttac gataatttaa ccgcaccgta
    33541 ttatcaagga tatatcctac ctctcttaac gttgaagaat actcatttag caattttatc
    33601 gaactatagt actatgacat ttgtcagccg tgaaaaacgc cctaattgga aaaatgaaga
    33661 ttttgataag tgggtgaaat atgtagcaac tgctcataga aaccatgttg atacttggta
    33721 taagatttta cctgataata tcaaaggtaa aatggttaaa gagaatgtta ctgctgtttg
    33781 ggaaggattg agcatcccag gaagtgaatg ggtagaccag aatgctgtag atagaaaagg
    33841 aagagattac gccccagctc gagaattctt taatcttgta ggtggtccta tgggaggttg
    33901 gtatgcttac catggttatg gtgcgcatgc tggaggaaga aatcgggtta attatgaggt
    33961 gtttgatgta ttaagtgagt atggtatatc ggtctttact catgaattga ctcacgttaa
    34021 tgatacttgg atttacttag gagggtatgg tagacgtgaa aatatgggac ctgaagctta
    34081 tgctcaggga ttattccagt ctcctgttcc aggtcagccg ggttgggggg cgcttggtct
    34141 caatatggca tttgaaagaa aaaatgatgg tgatctaatt tataatgcct ccccaactca
    34201 atttgaaaat aggaaagagt tagatagtta tatgaaaaat tataacgata ctctcatgat
    34261 ggtggactac ttggaaggag atgcagttat ctctaaaggt aaagaagcta ttactaaatg
    34321 gtttaaaaaa gttgaaccta aggttgttag tcaaacagct cagtatgata cggttcgtca
    34381 gttgactgct gaagagaaag aaaaactttc tgtttctagt gttgatgatt tagttgatca
    34441 aggattaatg tcagacagag ctgtaggaaa taatacctat aatccagctg attttgaaac
    34501 aagttatatt gcgatagatt atatgactgg tatttatggt ggaggaaaga atagtgtagg
    34561 ttcaccaggt gccttgatgt ttaaacataa tactttccgt atgtggggct actatggttt
    34621 tgaagaaggt gttctaggat atgcttctaa taaatttaag caagcatcta gagatgaagg
    34681 tcatgctgga cttagtgata actttattat ttctaagatt tccaaagggg aatttttaac
    34741 tatggaagca tttaaaaagg gatattttaa gaaagtagta gaagagttaa aaactaaagg
    34801 tattcgtcct gttactatca atcaaaaaac atatagcacc tttgaagaat tgcaagaagg
    34861 atttaagcag gctgttgaaa gagatttgaa gaaaaatcag ttagatgaga gggaaacaag
    34921 aaacttcaaa ttccaagttt tcagacaact tcttcaacaa acagatagct ttaaaacttc
    34981 tatctttaga taatcgaaat ctctcatctg ctttgcggat gagggttttc ttattttatg
    35041 ctatacttaa agtatgcata gaaaaacagt gattgatttt aggactttgg gggagagata
    35101 tacctttacc cagcctatta aagagttgaa aacgagaaat gtagaagaag tggcagattt
    35161 gctggcacaa gtggaaagct accaagagca aggttattat gtggtggggt atgtcagcta
    35221 cgaggctgca cctgcttttg aggaaaaatt agcagttcac aaggatcccc tactgggaga
    35281 gtacctgctt tattttactg ttcatgatag cgtagaaact tcccctattc ctctgactta
    35341 tgaggatatt gatttgccct caaattggca ggaagtaacg tctgcagcag actatgaaaa
    35401 ggccattgcc caaattcacc atcatttacg gcagggagat acctatcagg tcaactacac
    35461 cgtccaactt aagcaaaagt taaatgccaa tccttttgcc atctacaatc gtatggtggt
    35521 agagcaggag gcgggctaca atgcctatgt ggaacatgac gagatggcag tgatttccat
    35581 gagcccagag ctcttttttg agcaaaatga tcgcgagttg acaacacgac caatgaaggg
    35641 gacgactcag cgtggggtaa ctgaccaaga agatcttgaa caggccagtt ggttggaaca
    35701 ggatcccaaa aatcgctctg aaaatatgat gattgtggac ctcttgcgca atgatatgaa
    35761 ccgtatttct gaagttggga gcgagcacgt ggagcgtctg tgtcaggtag agcagtattc
    35821 aactgtttgg cagatgactt cgaccatcaa gagtcagttg cgagaggatg tggaccttgt
    35881 tgaaatcttc cactcactct ttccttgtgg ttccataacg ggtgcaccga aaattgcgac
    35941 aatggagatt atcaaggact tggagcctca accgcgtgga gtctactgtg gaacgattgg
    36001 tctcttgctt ccaaatggac gacggatttt taatgtggcc attcgtacca ttcaacttca
    36061 caaaggtcaa gccatttatg gagttggcgg agggattact tgggatagca cttgggaatc
    36121 tgaataccgt gaagttcatc aaaaggcagc agttctctat cgtaaacaag ctcgcttcca
    36181 attaattaca actggaaaaa tcagccaaaa acaactgatg tttgaagaac aacatctgga
    36241 aaggctgaga aaagctagtc ggtattttgc ttatcctttt gacccagaaa ttttgagaca
    36301 aaagattgaa gcagagtgtc agacttgtga tgctaatcaa gattaccgct tgcgaatttc
    36361 tctcagcaag tctggagaga tagaattcag tcgtcaaatc ttaacacctc ttagtccaag
    36421 tttttgtcag gccaaacttt gtctgcaaga agcgaatttg aatcaatcct ttacctattt
    36481 taaaacgact tacagaccgc atttgagcat agaggaacaa gagaagattt accataatgg
    36541 aaaaggagaa cttcttgaaa cctctatcgg aaatttggtt ctgaaaatcg atgggaaact
    36601 ctacacaccg cctatccgac ttggaatctt gccaggaatt tatcaccagt atttactaga
    36661 aacaggacag gtagaagaga aagtcttgac cttggcagat tttgcccaag cagaagctat
    36721 ttacggctgt aatgcagtga gaggcttgta tgagttgcaa gtgataggat tgtgagtttt
    36781 agctattaat agtttttaat atatattaaa atatattggt gtttactttt gatgagatat
    36841 catatttgtg ttataatgta accgtaaaca atagaaattt aaaggagatt tttgatgaaa
    36901 tcaaaaatag ttttgggagc ttcgctagcg atcgcaacac ttagcttagt atctcttgtc
    36961 gagattgaag gactctcacc gtttttaata gagaatgtta gcgcaaatac tcattctgca
    37021 aataaagtta ttaatcataa agtaagtatt tacttagaaa atgctgatga aggtaaaggt
    37081 ctaactgtaa acttttcaac agacagtgtt agtccaaatt tatttgatga gttcgaaaaa
    37141 aagagtggaa ttacaataac tactatgtta gtgaatgcta agacaggtga agttgtagaa
    37201 aaaagattaa caccaagcgt ttttttacgt tccaatgatt taaccagtgg gaccatatct
    37261 tcgtttattt ttagtgaata tcctgatgga gaatataaat atgttgtgtc taaaggagac
    37321 tttatcgatc ctaagactca gtttaaacat cagtatagag gagaatctcc agtttttaga
    37381 atacgtaatc gaaaatatgt ggagttggga acaactgata aaaaattaga tgaaagacgt
    37441 gataatagcg tttataaaga tggggttgtt gaacacaagg taaatttaag tttaacaagt
    37501 tatcaaggag gtaatggagt tactgcaatt ttttcaactg atagtgttaa ctctaactta
    37561 cttaattctt ttggtgaaaa ggctaaaaaa gttttgatta ggtctaagtt aattaatgtt
    37621 aagactggcg aggttattga tgaaacgttt tctccaaaag taagtttaac ctctaaaatt
    37681 ttgaaaagtg gttctacagc agtattttat tttatagatt taactgatgg cgaatataaa
    37741 tatgttgcgt atgaaagcca gcaatatact gatcctcaaa caacattgac tcatcagtat
    37801 agaggagaat ctcctatttt tagtatcaaa gatggaaaat tttctggttt agtatctgcc
    37861 tcaaaaccag acgaaaaccc gaagccaacg ccaaaaccgg atgagaaacc aaaaccttca
    37921 gcaccacaac aggagaaaac aaaacctaca gttcagtctg gttgggtagg ttcatcttat
    37981 tatcaaaatg gtaaaaaagt cactagtaag tggatttttg ataaaaaata taattcatac
    38041 ttctatctag atgcatcagg aaattatgtt caaaacgctt gggtaggtaa ctattatctc
    38101 aaatcaggcg gatacatggc taaaagtgag tggatttatg ataagaacta tggttcatac
    38161 tactatctaa catcagaagg cagctacgct cgtaacactt ggtcaggcaa ttattatttg
    38221 aagtcaaatg gtaagatggc taaaagtgag tgggtatacg atagtaacta caaatcatat
    38281 tactacttga catcagaagg aagttatgct cgtaacactt gggtaggcaa ttactatctt
    38341 aaatcaaacg gtaaaatggc tgttaatgaa cgtacaccag atggttatcg tgtagatggt
    38401 tcaggtaaat gggttaaata agaaactaaa aaataggata ataggtaata tcagatgaat
    38461 aaaaaaaatt attttcatgt gctttagcat tttcaacgat tggaacattg tcaacgattg
    38521 ataaatcagg agttcttcct ttttcagcgc aaacggtgca ggctgacata caaacgctta
    38581 ccccaatggc aaaatattat attattcttc cgaaggatgc agaaatatat aaaacttgga
    38641 gaggtactgt caatattccc attattgatg ctacaaaaac tactccagaa ttatcttatt
    38701 tcaaagaaga tcatcgcaac tatatagcta atgagaataa gtctggtgcc aattacatag
    38761 agtggaaggg aacagtagaa gagtttaaag aggccattaa gaagttgact gataaaaaat
    38821 caactactgc aacaccaaaa aaggatgaaa agccaacacc aaaaccggat gagaagccaa
    38881 aaccaacacc tacagttcag tctggttggg taggttcatc ctattatcaa gatggtaaaa
    38941 aagtcattag taagtggatt tttgataaaa aatataattc atacttctat ctagatgcat
    39001 caggaaatta tgttcaaaac gcttgggtag gtaactatta tcttaaatca ggcggataca
    39061 tggctaaagg tgaatgggtt tatgatgcca cctatcaagc ttggtattat ttgacatcag
    39121 atggttctta tgcttacagt acatggcaag gaaattacta tctaaaatcg gatggtaaaa
    39181 tggctgtcaa tgaatgggtt gatggtggac gttattatgt tggcgctgac ggagtttgga
    39241 aggaaggtca agcaagtaca gcttcttcta gtaatgatag caatagtgaa tattctgctg
    39301 ctttaggaaa ggcaaaaagt tataattcgt tattccacat gtcaaaaaaa aacgtatgta
    39361 tagacaatta acttctgatt ttgataaatt ttcaaatgat gcagctcaat atgccattga
    39421 tcattagatg attaacagat actggtaggc gaaaaaattc cttataatcc atttacgcaa
    39481 acctttgcat aagtgaatgg attttgatat actagtactg taagcatttt caattactac
    39541 acaatgaaaa aggagaatat gatgagtcaa aagattattg ggattgacct tggtggaact
    39601 tctatcaaat ttgcaatctt aacaacagca ggagaaatcc aaggaaaatg gtcaatcaag
    39661 accaacattt tggatgaggg aagtcatatc gttgatgata tgattgagtc tattcaacat
    39721 cgtttggact tgcttggatt ggcagcagcg gacttccaag gcattggaat gggatcacca
    39781 ggtgtggttg accgtgacaa agggactgtt atcggtgcct acaacttgaa ctggaaaacc
    39841 cttcaaccaa tcaaacaaaa gattgaaaaa gctttgggca ttccattttt catcgataat
    39901 gatgccaacg tagcagctct tggtgagcgc tggatgggtg ctggagataa ccaaccagac
    39961 gttgtcttta tgacactcgg tactggtgtt ggtggcggta tcgtcgcaga aggcaaattg
    40021 cttcacggtg ttgctggtgc agcaggtgag cttggtcaca tcactgttga ctttgaccag
    40081 ccaatctcat gtacttgcgg taagaaaggc tgccttgaga cagttgcttc agcaacaggg
    40141 attgtcaact tgactcgtcg ctatgccgat gaatacgaag gcgatgcagc cttgaaacgc
    40201 ttgattgata atggagaaga agtaactgct aagactgtct ttgatctcgc aaaagaagga
    40261 gacgaccttg ctttgattgt ttaccgtaac ttctcacgtt acttgggaat cgcttgtgct
    40321 aacattggtt caatcctaaa cccatcaaca atcgtcatcg gtggtggtgt gtcagctgcg
    40381 ggagaattcc ttctacaagg tgttcaaaaa gtttacgatg aaaatagttt cccacaagta
    40441 cgcacatcta ctaaattagc tcttgcaact ctaggaaatg acgctggagt tatcggagca
    40501 gcatcacttg tattgcaata agataatgag agaggaaaat gctaacctag agttagtaat
    40561 gttcctcttt tattttttat gctatactag ttaggacaat gaatgaggtg agagtaaatg
    40621 acaaaagcag atacgatttt taaagagaat attgaatgca ttctaaagga aggtgttttc
    40681 tcagagcaag ctcgtcctaa gtacaaggat gggactgttg ctaattccaa gtatgtaact
    40741 ggtgcctttt ccgagtacga cttatctaaa ggagaatttc ctatcacaac cttgcgtccc
    40801 attgcaatca aatccgccat caaagaagtt ctctggattt accaagacca gtcaaatagc
    40861 ttagaagtgc ttaatgacaa gtacaatgtt cactactgga atgactggga agttggagac
    40921 acgggaacca ttggtgagcg ctatggtgcc gttgttaaga aacacgacat tatcaataag
    40981 cttctcaaac agttggaaac caatccttgg aatcgccgca atattatttc gctctgggat
    41041 taccaagctt tcgaagaaac agatgggctg ctcccgtgcg cctttcagac catgtttgat
    41101 gtccggcgtg ttgatgggga aatctatctg gatgcgacct tgacccagcg ctccaatgat
    41161 atgctggtgg cccaccacat caacgctatg cagtatgtgg ctttacagat gatgattgcc
    41221 aaacattttg gttggaaggt tgggaagttc ttctatttca tcaacaacct ccatatctat
    41281 gataatcaat ttgaacaagc tcaggaattg ctccgtcggg agccgtcaaa ctgccaacca
    41341 cgcttggttt taaatgttcc tgatgggact aatttctttg atatcaaagc agaagatttt
    41401 gagttggtgg attatgaccc tgttaagcca cagttgaagt ttgacctagc tatttaaaag
    41461 aatagaaaaa agaagttgag aataatccca acttcttttg tttcttaacg tgatacgcgg
    41521 cgacgagctg cttttttacg attttcttcg atgaaagctg ctttttgctc ttctggttcg
    41581 attactttct ttttaaatgc gtatactgca cctgcaacgg cagcgacagt tcctgcgaca
    41641 cctgttacaa gacctttagc gaatccttta gccatgagtc ttcctccttt atattctcaa
    41701 tcagccagcc tcctcaagag gtcacatttt tctgactgac ctttttgtgt tataataata
    41761 gtaacgaaaa aatgggaatt tttcaaggaa aaaagatgaa aacaaaaata attgtgattg
    41821 ttggaccgac tgctgttgga aagacggctc tagctattga agttgcaaag cgctttaatg
    41881 gcgaagtggt tagtggagat agccagcaag tctatcgagg acttgatatt gggacggcca
    41941 aggctagtcc agaagagcag gcagctgttc ctcatcattt aatcgatgtt agagagataa
    42001 ccgagtctta ctcggctttt gattttgttt cagaagctaa gatgactatt gaggatattc
    42061 agagccgtgg caagctagcc attatcgccg gtgggactgg actttatatc cagagcttgc
    42121 tagaaggtta ccacctaggt ggggagactc ctcatgagga gattttagct tatcgagcta
    42181 gtttggagcc atattcagat gaggaattag cccatttggt ggagcaagca ggccttgaga
    42241 ttccccagtt taatcgtcgt cgtgctatgc gtgccttaga aattgcccat tttggtcagg
    42301 atttggaaaa tcaagagatc ttgtatgaac cgctgattat ctgcttggat gatgaacgta
    42361 gtcaacttta tgagcgtatc aaccaccgag tggatttgat gtttgaggct gggcttttgg
    42421 atgaggccaa gtggctgttt gaccattccc ctaatgtaca ggctgctaaa ggaattggct
    42481 ataaggaact ctttccttat ttccgtggag agcagacctt tgaggaagct cgtgagagtc
    42541 ttaaacaggc gacccgtcgt tttgccaagc gtcagctgac ctggttccgt aatcgcatgc
    42601 aggtcacctt ttatcagatt ggagaatctg gtgtacaaga ccgcatttta agccagatag
    42661 aggagttttt agatgattga aacggagaaa aaagaggagc gagtcctgct gattggtgtg
    42721 gaattgcagg gtatggacag ttttgacctc tccatggaag aattggctag tttagcgaaa
    42781 acggcagggg cagtcgttgt agatagctac agacaaaaac gtgaaaaata tgattccaag
    42841 accttcgtcg gctctggtaa gttggaagag attgcgctta tggtggatgc agaagaaatc
    42901 actactgtca tcgtcaacaa tcgtctgacc ccaaggcaga atgtcaatct agaggaagtt
    42961 ctcggtgtta aggtcattga ccgtatgcag ttgattttgg atatctttgc catgcgggct
    43021 cgaagccatg aagggaagct ccaagtccac ctagcccaac tcaaatacct cttgcctcgc
    43081 ttggttggtc aggggattat gctcagccgt caggcagggg gaattggttc ccgtggtcct
    43141 ggtgaaagcc aactggagct gaaccgtcgt agcgttcgca atcaaatcac ggatatcgag
    43201 cgccagctta aggtggttga gaaaaatcgt gcgactgtca gagaaaaacg tttggagtct
    43261 agcactttta agattggttt gattggttat actaatgctg ggaaatcaac tatcatgaac
    43321 atcttgacca gtaagaccca gtatgaagca gatgagctct ttgcgactct ggatgcgaca
    43381 accaagagta ttcatctggg aggcaatctc caagtaactt tgacagatac cgttggcttt
    43441 atccaagatt tgccgacaga gttggtgtcc agtttcaagt caaccttgga agaaagcaag
    43501 catgtggacc ttctggttca tgttatcgat gctagcaatc cttaccacga ggagcatgaa
    43561 aaaacggttc tctccatcat gaaagacctg gacatggaag atattcctca cttgacgctt
    43621 tataataaag cggatttggt ggaggatttc acgcctaccc aaacgccata taccctcatt
    43681 tctgccaagt ctgaggacag tcgtgaaaac ttgcaagcat tattgctaga taagattaag
    43741 gaaatttttg aagcatttac cctgcgagtg cctttttcaa agtcctacaa gattcatgat
    43801 ttagagagtg ttgcaattct ggaagaacgt gattatcagg aagacggcga agtgattaca
    43861 ggctacattt ccgagaaaaa taaatggagg ttagaagaat tttatgactg atattaaaac
    43921 tttggctcta aagtatggag gttatacaag tctggacaag gtctatctgg atcagcttct
    43981 agctggtaaa acagatcagg agcagttaac acttattaca cctccgccaa gtgttgttaa
    44041 tgcctacttt gcagaactct atcagaaaaa gagtcctcag gctgcgacgg attattttgc
    44101 agaactcagt caggaactga atctttacaa tactgagcca agtttcaccc tagaaaataa
    44161 gccttttatt cggcttaatc tgtctggtaa atcctttggt ttttgttatg agagtgacgg
    44221 ccttggtcgg attttctttg aaaatgagga gaaaatctcg gatgacttgc tctttgaaat
    44281 tgcgcaaatt ttcccccatc aattagtctt tgaagagtct ggtaagattt acatgaagcc
    44341 tgtcgaggac gaggaagtta tcagcctaga aagtctcaca gctttgactg atttggaaag
    44401 attggctgat ggtcgaaaac gtctcaaagg ctacagccaa gaggatttat tgcaagaagc
    44461 tgctgctttt tctggcaaac gctatttccg atcggaaaac cgcacagcca tgttatatat
    44521 tgattaatta gaaagtatcg aatggatatt caatttttag gaacgggggc tggtcagccc
    44581 tctaaagccc gcaacgtttc aagtctcgcc ctgaaacttt tggatgagat taacgaagtt
    44641 tggctctttg actgtggaga aggtacgcaa aatcgcattc tggaaaccac aattcgacca
    44701 cgtaaggtca gcaaaatctt tattacccat ctgcatggag accacatttt tggtttgcca
    44761 ggtttccttt ctagccgtgc ctttcaggcc aatgaagagc agacagattt ggaaatctac
    44821 ggacctcaag gaatcaagtc atttgtctta accagccttc gtgtgtcagg ttctcgtctg
    44881 ccctaccgca ttcatttcca tgagtttgac caagattctc tgggtaaaat tcttgaaacc
    44941 gataaattca ctgtgtatgc agaggagctg gaccacacta ttttctgtgt tggctatcgt
    45001 gtcatgcaaa aggatctaga agggacgctg gatgctgaaa aactcaaggc tgctggtgtt
    45061 ccgttcggcc cgctttttgg taaaatcaaa aacggccagg atcttgtttt ggaagacgga
    45121 actgaaatca aggcagcaga ctatatctca gcgccacgtc caggtaagat tatcactatt
    45181 ttaggagaca ctcgaaaaac gggtgccagt gtgcgtctgg ctgtcaatgc agatgtccta
    45241 gttcatgagt ccacttatgg caagggtgat gaaaaaattg ctcgtaacca tggtcactca
    45301 actaatatgc aagctgcaca agtagcggta gaagcaggtg ccaaacgcct cctactcaac
    45361 catatcagtg cccgtttcct ctcaaaagat attagcaaac tcaagaaaga cgctgccaca
    45421 atttttgaaa atgtccatgt ggtcaaagac ttggaagaag tggaaatcta gcagtcacag
    45481 aaaggataag tatgcctact attctcatta ccggagctag cggtggtcta gctcaagaaa
    45541 tggtcaaact cctgcccaat gaccaactca tcttgcttgg tagaaataag gaaaaattag
    45601 cccaactcta cggaaattat tcccatgcag aattgattga aattgatatt accgacgatt
    45661 cagccctaga agctctggta actgatcttt atctccgcta tggcaagatt gatgtcttga
    45721 ttaacaacgc tggttacggg atttttgagg gatttgacca gattgctgat aaagatattc
    45781 accagatgtt tgaggtcaat acctttgccc tgatgaatct gtctcgtcac cttgcggctc
    45841 gtatgaagga aagcagcaaa gggcatatca tcaacatcgt cagcatggca ggtctaatag
    45901 ctactggcaa gtctagtctt tactcagcga ccaagtttgc ggctattggt ttttcaaatg
    45961 ctctgcgact cgaacttatg ccctatggag tctatgtgac aacagtcaat ccaggtccaa
    46021 tccgaacagg atttttcgac caagccgacc cagatggaac ttatcttaaa tcggttgacc
    46081 gcttcctgct agaaccagat gcagtggcta aaaagattgt caagattata ggaaaaaaca
    46141 aacgagaact caatctcccg attttgttga acctagctca taagttttat accctctttc
    46201 ctaagctagc tgataagttg gcaggggaaa cttttaatta taagtaaaaa gaaccaatgt
    46261 gcaggttgtt gctagcctac atattggttc ttatcatttc tcaactatca aactgaactt
    46321 cttctaggag atagtctata aagcgttcgc ccatcttaga taggctggtt ttctcatgct
    46381 ggatatagac cagctcgatc gggtcatcaa tatccagtgg gatagaaacg atattgtctc
    46441 cgtttaggtt gctgttcaaa atccctgtcg caatggtata accatccaaa ccaatcaaga
    46501 gattaaagag ggtggcacgg tcactgacca caatggattt cttgtggtgt tcttgagaaa
    46561 gaatctcttc tgaaaagtag aaggaattgt gcgtcccttg gtcatagctg aggtaaggga
    46621 aattctccaa atcagacagt ttcaccttgt ctttctttgc cagagggttg gtcttgctga
    46681 caaagatatg tggttgcgct gtgaagagat ggtgggctag caggtgattg tcatccagca
    46741 tcttggttaa aacatcacgg ttgtaactgt ttaagaagag gaccccgacc tcactgcgga
    46801 agttcttgac gtcgtcgata atctcccaag tccgagtttc acgaaggaag agttcgtatt
    46861 tctccatatc gcttttcttg agcaaagaga caaaggcatt gaccacaaag gcatagtgtt
    46921 gagacgaaac gctaaatagt tcgcggtggg cgacaggatt tttatagcgt tcctccagaa
    46981 gctgggtctg ctcgacaacc tgacgggcat aagagagaaa ctccatccca tcacgggtca
    47041 aggtgattcc cttgggattg cggataaaga tctcaatgcc catttcattt tccaaatctc
    47101 gcactgcatt ggagagactt ggctgagtga taaagagttg cttggctgcc tcattcatgg
    47161 agccagtttc gacgattttg ataatataat gtaattgttg aattctcatg tttttattgt
    47221 accatacttg ccttagaatc gctaaagaag ataggaaaat aaggagcatt gtgtgagtct
    47281 cttcttgaaa aaaacacaaa attttgctag aatgagtctt atgaaaacat tctatgatgt
    47341 gcagcaattc ctcaaacgat ttggtattat tgtttacatg ggaaaacgct tatatgatat
    47401 tgaactgatg aagttggaac tatctcggat ttacgatgca gggttgatgg ataaattaga
    47461 ctatctagag gcagaagcag ttcttcgcag agagcacaag gtagaattgg attatattga
    47521 gaaaaatgga gaaaagaact aatggttact tggattttgt gggcacttat actagcaatg
    47581 ttggcgtgga tgggctttaa ctatcttcgt attcgccgtg cggctaaaat tgtggacaat
    47641 gaggagtttg aagccttgat tcgtacgggt caattgattg atttgcgcga cccagcagaa
    47701 ttccacagaa aacatatcct tggtgcacgc aatattcctt caagtcagtt gaaaactagt
    47761 cttgcagccc ttcgtaaaga taaacctgtc cttctctacg agaaccaacg tgcgcaacga
    47821 gttacaaatg cagctcttta cttgaaaaaa caaggttttt ctgagattta tatcctttct
    47881 tatggcttgg attcttggaa agggaaagtg aagactagct aaccttattt ccaaattagt
    47941 cgaatgatag gatgaagcta ttgttttata gtataattaa tttgtataaa atttaaggag
    48001 ttcttagaac ataaaagaaa agaagaaaaa tccacttttt gtgggtatct tgtcgattat
    48061 tcttggtttg ttatttccaa ttgtaggcct gattttgggt atcataggat tggtcttggc
    48121 tatttcatac caaaaagagt cataattaga ctataaaata gaaaagattc ttaatatctt
    48181 aggaattgtg atttctgtag ttaactggat tgtagcaatc gccttaattt ttcggtaaat
    48241 aaaagaaaaa agctttagtt ttaaagcttt ttttgtttta tcgactcatc tctaaatagt
    48301 ttttaatgat ttgtaactct ttttggttca aagggcggta gttactttct gctaaatctg
    48361 ggttcaatgt gaagtcccca aattggattc tcttgaggat agtcacctta acaccaaccg
    48421 agaggaacat tttcttgatt tgatgaaatt ttccttctga aatggtgata gaggcttgac
    48481 tgatggaggg acttgcagat agaatctcta gttttgcggg tttacagaca gtaccatcta
    48541 aaaagacaat tcccttttga aaggcttgga tatggtcagg tgttagaagt ccattaacct
    48601 caacttgata agtcttatcg acatgatatt ggggatggag gagttggaag cccaagggac
    48661 cgttatcggt caagaggagg agtcccgttg tatctcggtc cagtcggcca acggcataga
    48721 gcttgtcaga ctggatgtca gatggaagca ggtccatgac ggtcggaagt tccttgtctt
    48781 tgttggctgt aacgacacca gcaggtttat gaagcataag ataggtgtgt tcatagcctt
    48841 gaatgattcg atcctgaaaa aggagttctt gtagtcctgt atcgatattt tgagctaggg
    48901 agcgggctgg gcaaccatcg actagaattt tccctctgag gagtgcttgc ttcatggcct
    48961 ttcggctgat tttttcttgg gctaataaat tatctaaacg catactgtgc ctatcttatc
    49021 ataagtcgct tgctttgaaa aggcttgacg tgaaaagaaa agcggagtga aaacatttac
    49081 acttgcttga gttatgttat ttatttgaaa ttatggtata atcgttcagt tagaaaataa
    49141 attttgaata ttatagagga aatcatgaca aaattaagag aagatatccg taacattgcg
    49201 attatcgccc acgttgacca cggtaaaaca accctggttg acgaattatt gaaacaatca
    49261 gaaacgcttg atgcacgtac tgaattggca gagcgtgcta tggactcaaa cgatatcgaa
    49321 aaagagcgtg gaatcaccat ccttgctaaa aatactgccg ttgcttacaa cggaactcgt
    49381 atcaacatta tggacacacc aggacacgcg gacttcggtg gagaagttga gcgtatcatg
    49441 aaaatggttg acggtgttgt cttggtcgta gatgcctatg aaggaaccat gccacaaact
    49501 cgtttcgtat tgaaaaaagc cttggaacaa gaccttgtcc caatcgtggt tgttaacaaa
    49561 atcgataagc catcagctcg tccagcagaa gtagtggatg aagtcttgga acttttcatc
    49621 gagcttggtg cagatgacga ccagcttgat ttcccagtgg tttatgcttc agcgatcaac
    49681 ggaacttctt cattgtcaga tgatccagct gaccaagaag cgactatggc accaatcttt
    49741 gacacgatta tcgaccatat cccagctcca gtagataact cagatgagcc tttgcagttc
    49801 caagtgtcac ttttggacta caatgacttc gttggacgta tcggtatcgg tcgtgtcttc
    49861 cgtggtacag ttaaggttgg ggaccaagtt accctttcta aacttgacgg tacaactaaa
    49921 aacttccgtg ttacaaaact cttcggtttc tttggtttgg aacgtcgtga aatccaagaa
    49981 gccaaagcgg gtgacttgat tgccgtttca ggtatggaag acatctttgt cggtgaaacc
    50041 atcactccga cagatgcagt agaagctctt ccaatcctac acatcgatga gccaactctt
    50101 caaatgactt tcttggtcaa caactcacca tttgctggta aagaaggtaa atgggtaact
    50161 tctcgtaagg tggaagaacg cttgcaggcg gaattgcaaa cagacgtttc ccttcgtgtt
    50221 gacccaactg attcaccaga taaatggact gtttcaggac gtggagaatt gcacttgtca
    50281 atccttatcg aaacaatgcg tcgtgagggc tatgaacttc aagtatctcg tccagaagtt
    50341 atcgtaaaag aaatcgacgg tgttaaatgt gaaccatttg aacgtgtaca aatcgacact
    50401 ccagaagaat accaagggtc tgttatccaa agcctttctg aacgtaaagg tgaaatgttg
    50461 gatatgattt caactggtaa tggtcaaact cgtttggtct tccttgttcc agcgcgtggt
    50521 ttgattggat actcaactga gttcttgtca atgactcgtg gttacggtat catgaaccat
    50581 accttcgacc aatacttgcc attgattcca ggggaaattg gtggacgtca ccgtggtgcc
    50641 cttgtttcta tcgatgctgg taaggctaca acttactcaa tcatgtctat cgaagaacgt
    50701 ggtacgatct ttgtcaaccc aggtactgag gtttatgaag gaatgatcat cggtgaaaac
    50761 tctcgtgaaa atgacttgac agttaacatc acgaaggcaa aacaaatgac caacgttcgt
    50821 tcagctacta aggaccaaac agctgttatc aagacgcctc gtatcttgac acttgaagag
    50881 tctcttgagt tcttgaacga cgatgagtac atggaagtaa cgcctgagtc tatccgtttg
    50941 cgtaaacaaa tccttaacaa agcagagcgt gagaaagcta acaagaagaa aaaatcagct
    51001 gaataagagc tagaaagaga gaaagatggt ctatttagtc ctaggaattt tactgctcct
    51061 actctatgta tttgcgacac cagaaagcat taaagggaca gtcaatatcg tcgctatggt
    51121 atgtatttta gtggcactct tgattttatt ggttctatct tttctgaaaa tttttcaatt
    51181 accaacagaa atattcctag caatagccat gttgctccta gcttacttta gtgttagaga
    51241 cattacactc atgccagtca aaaaaagtaa aagaagataa aaaagagagt tttggctctc
    51301 ttttttgcta ggaattttac aagattgcaa tttatttttg agttatcacc atctcttttg
    51361 tttggataat atgaatggga aaaacttgaa taaaattcgt taatggaatc tattttatat
    51421 ttggttagta ctggttgcat attattttga aataaaacta ctatataata ttattcatag
    51481 aggtaatata gtaaaatatc taaaaaattc gattttttcc ttgacaacaa ataataaaaa
    51541 tgttattctt atcacataag aaagcggttt caataaaaga gagaggagga tttattttgt
    51601 tgcattgttg ctcaaggtgt gatttttttg aaagaaaaaa taaaatgaaa acgaaaaaac
    51661 atagattact tgctctagct cttatttcaa gttttacatt attgggagct gcatcagctg
    51721 ctgtataata tccagatgga ggagtatgga catatggaga aggttcagga ggtggttagg
    51781 ctttttcaaa ttactatcat ggtaaaaaat atcattattc atccatcgtg agcagatggg
    51841 atggtcattc tgataaagga gaagctcctg ctggaaaaac ctcctatgca tggatttgga
    51901 ctaaatgggg agaacaagta gcattttact gtgattatga ctaatcgttc attgatttaa
    51961 atcgttcccc ttgtaagaaa ttacaggggg aattttgttt acaaggagtc taccaaggag
    52021 tctactatga agaaactatt catattatta tcaacttttt ttctcagctt cttccttgct
    52081 tggattattg tcttacgtgc gccacaatat ttatatgcaa gctatgattc cgtttcttta
    52141 cttcgtgtca aaaaagatac tcaggaaccg acgcgtgagg tatttgaaca ggaattggag
    52201 aattttgcaa actcagaaca gagtttaata gctagaagaa ttgtagagcc gagtaaggat
    52261 gggacgactc actttactta tgcaacttat ggtcagggaa ctttaccaaa agaattccaa
    52321 gaagctagcc aagaaagtcg tgaacgtagt gatccgctaa atagttatct ccttttgtca
    52381 ggctccttga cgaaagaaaa gcttgccgat aaattaggag atttgggtta taaagcaagt
    52441 gctgaccgaa agataccgcc ctattttctt gcttttcgaa tattactaaa tccccttatt
    52501 ttaattagtt tagcaatatt tggcttatct ttctttgctt tagtgattat cactcggatt
    52561 aaggaaatga gagcagcagg tataaaactc ttttctggtc agactctctt atccatcatg
    52621 gggcattctt tatctactga tatcaaatag ctccttctat cagccctcct ttccttccta
    52681 ggtgggggag tcgttctttt tagtcaaggt ttgttttatc ctatcttgtt agccacctat
    52741 ggttttggga ttagtttcta tctgttgttt ttattggcga tttcaatttt actaatgctt
    52801 ctttatctaa tgagtttgag ttacaaagca ttagttcccg ttattaaggg gagattaccc
    52861 cttaaacgcc tgatgatttt aaccctattg tgtcagttgg ttgctgtctt tacagtagga
    52921 tacgctgtta agacaggttt gacgtcttac caacgattga aagaacttga aatttcaaaa
    52981 caagcatggc aggatagagc agactattat caaatttctt ttggcttagg tgatagagga
    53041 aaagatacag aaaatcagag caagtggtat gcctttgcca aggaagcaat cgaagaggaa
    53101 caagctcttt atgtaaagga taatctgctc cattttgcca atccacaagg aaaaaatgaa
    53161 cagggagaga cactggatac ctatagtcca gatgctaata cgctctatgt tagtcccagt
    53221 tatttggaca aggaaaaggt cgtggtagat gctgagacca aacagaagtt agcccatctc
    53281 caaaaaggtg agtttatcct cttgctccca gaacatttgc gctctcgaga agcagaactt
    53341 aagaaagttt ttgaagaaag attgagttat tatggaaaat ctggtgagga ggcaagtgct
    53401 cctttggatt atgagatgaa agcgcacgtt agttatcttt caatgggaga aaagcggttt
    53461 gtttataata acggtgagaa tcccgtatct actcagtatt tgactgatcc gattttagtg
    53521 gtattcacgc cgacttctac aggtgatagt tttatatcct tatctagttg gtctatcaat
    53581 gctggaaaac aactctttat caaaggatat gagagtgggc tagaactctt gaagaaagct
    53641 ggaatttatg agcaagtatc ctatcttaaa gaaggaagaa gtgtttatct aactcgttat
    53701 aatgaagttc aaactgaaac agcaacttta atcttaggag ctattgtggg gatagctagt
    53761 tccttattac tattttattc tgtcaatctt ctatatttcg agcaattccg ccgagatatc
    53821 ttgattaaac gaatttcagg tttacgattt tttgaaacac atgctcagta tatggttagc
    53881 caatttgcca gttttgtatt tggtgctagt ctctttattt taagcagtcg agacttggtg
    53941 attggcttgc tcactttatt ggtctttcta gctagtgcag ttttgacgct ttaccgtcaa
    54001 gcgcagaaag aatctcgtgt ttctatgaca attatgaaag gaaaatagga tgattgaact
    54061 aaagaatata tctaaaaaat ttggaagccg tcagctattt tcagatacga atcttcattt
    54121 tgaaggtggg aaaatttatg ccttaatcgg tacaagtggc tgtggtaaga caacactctt
    54181 gaatatgatt ggacgattgg agccatatga caaagggcaa atcatctatg atggcacttc
    54241 tcttaaggac atcaagcctt ctgttttctt tagagattac ttaggatact tatttcaaga
    54301 ttttggctta attgaaagcc aaaccgtcaa agagaatctc aatctgggtt tagttggtaa
    54361 aaagttgaag gaaaaagaga aaatctcttt gatgaaacaa gctctaaact gtgtaaacct
    54421 ctcttatttg gatttgaagc aacctatatt tgagttatca ggaggagaag cacaacgtgt
    54481 tgcactagcg aagataattt taaaggatcc gcctttgatt cttgcagatg aaccaaccgc
    54541 ttccttagac cccaaaaatt ctgaggaatt actttccatc ctagaatctt taaaaaatcc
    54601 gaatcggacc attattattg cgacccacaa tcctctgatt tgggagcaag tggatcaggt
    54661 cattcgagtt accgatttat cacatagatg atatggtaag attcagttag aagaaagagt
    54721 cacaaacaca ctttgtggct tttttatttc cataaaaatg gtaaaatagt aggagtagaa
    54781 atggagttcg agacatgaaa gtaatagatc aatttaaaaa taagaaagtt cttgttttag
    54841 gtttggccaa gtctggtgaa tctgcggctc gtttgttgga caagttaggt gccattgtga
    54901 cagtaaatga tgggaaacca ttcgaggaca atccagctgc ccaatgtttg ctggaagaag
    54961 ggatcaaggt cattacaggt ggccatcctt tggaactctt ggatgaagag tttgccctca
    55021 tggtaaaaaa tccaggtatc ccctacagca atcccatgat tgaaaaggct ttggccaagg
    55081 gaattccagt cttgactgag gtggaattgg cttatttgat ttcagaagca ccgattattg
    55141 gtatcacagg atcgaacggt aagacaacca caacgactat gattggggaa gttttgactg
    55201 ctgctgggca acatggtctt ttatcaggga atatcggcta tcctgccagt caggttgctc
    55261 aaatagcatc agataaggac acgcttgtta tggaactttc ttctttccaa ctcatgggtg
    55321 ttcaagaatt ccatccagag attgcggtta ttaccaacct catgccaact catatcgatt
    55381 atcatggatt atttgaggaa tatgtagcag ccaagtggaa tatccagaac aagatgacag
    55441 cagctgattt ccttgtcttg aactttaatc aagacttggt aaaagacttg gcttccaaga
    55501 cagaagccac tgttgtacca ttttcaacac ttgaaaaggt tgatggagct tatctggaag
    55561 atggtcaact ctacttccgt ggtgaagtag tcatggcagc gaatgaaatc ggtgttccag
    55621 gtagccacaa tgtggaaaat gcccttgcga ctattgctgt agccaagctt cgtgatgtgg
    55681 acaatcaaac catcaaggaa actctttcag ccttcggtgg tgtcaaacac cgtctccagt
    55741 ttgtggatga catcaagggt gttaaattct ataacgacag taaatcaact aatatcttgg
    55801 ctactcaaaa agccttatca ggatttgaca acagcaaggt cgtcttgatt gcaggtggtt
    55861 tggaccgtgg caatgagttt gacgaattgg tgccagacat tactggactc aagaagatgg
    55921 tcatcctggg tcaatctgca gaacgtgtca aacgggcagc agacaaggct ggtgtcgctt
    55981 atgtggaggc gacagatatt gcagatgcga cccgcaaggc ctatgagctt gcgactcaag
    56041 gagatgtggt tcttcttagt cctgccaatg ccagctggga tatgtatgct aactttgaag
    56101 tacgtggcga cctctttatc gacacagtag cggagttaaa agaataaaat atgaaaaaaa
    56161 ttgtctttac aggtgggggg acggttggac acgttaccct caatcttttg ttaatgccca
    56221 agttcatcga agatggttgg gaagtccact atatcgggga caagcgtggt atcgaacacc
    56281 aagaaatcct taagtcaggt ttggatgtca ctttccactc cattgcgact gggaaattgc
    56341 gtcgctattt ctcttggcaa aatatgctgg acgtcttcaa agttggctgg ggaatcgtcc
    56401 aatcgctctt tatcatgttg cgacttcgtc cacagaccct tttttcaaag gggggctttg
    56461 tctcagtacc gcctgttatc gcagcgcgtg tgtcaggagt gcctgtcttt attcacgaat
    56521 ctgacctgtc tatgggcttg gccaataaaa tcgcctataa atttgcgact aagatgtatt
    56581 caacctttga gcaagcttcg agtttgtcta aggttgagca tgtgggagca gtgaccaagg
    56641 tttcagatca aaaaaatcca gaaccagatg aattggtgga tattcaaacc cactttaatc
    56701 ataaattgcc gactgtattg tttgttggcg gttctgcagg tgctcgtgtc tttaaccaat
    56761 tggtgacaga ccataagaaa gaactaacag agcgctacaa tattatcaat ctaactggag
    56821 attctagcct gaatgagttg agccaaaatc tttttcgtgt tgactatgtg accgatctct
    56881 atcaaccctt gttggaattg gctgatattg ttgtgacacg aggtggtgcc aatacgattt
    56941 ttgagctctt ggcgatagca aaattgcatg tcattgtgcc gcttggtcgt gaagctagtc
    57001 gtggtgacca gattgaaaat gcagcttact ttgtaaaaaa aggctatgca gaagaccttc
    57061 aagaaagcga tttgaccttg gatagtttgg aagagaagct ttctcactta ctaagtcaca
    57121 aggaagatta ccaagctaag atgaaagctt ctaaggaatt gaaatctcta gcagattttt
    57181 atcaattgtt gaaaaaagat ttatcataag gaaagtaaat gtcaaaagat aagaaaaatg
    57241 aggacaaaga aatcctcgaa gaattgaaag agttatcaga atggcagaaa cgaaaccaag
    57301 aatatctaaa aaagaaggct gaagaagaag cggctctagc tgaggagaag gaaaaggaaa
    57361 gacaagctcg gatgggagaa gaatctgaga agtcagagga caaacaggac caggagagtg
    57421 aaacagacca ggaagattca gaatcagcta aggaagagtc tgaagaaaaa gtagcatcct
    57481 cagaggatga caaagagaaa gaagagaaag aagaaccaga gtctaaagag aaggaggaac
    57541 aggataaaaa gcttgctaaa aaggctacaa aggaaaaacc agccaaagca aagattcctg
    57601 gtatccatat cttgcgagcc ttcacgattt tatttccaag tctgctttta ttgattgtct
    57661 ctgcctactt gctcagtcct tatgcgacca tgaaagatat tcgtgttgag ggaacggtgc
    57721 aaactacagc tgatgatatt cgacaggctt caggcattca ggattcggat tatacgatta
    57781 accttctgct agacaaggca aaatatgaaa agcagattaa gtctaactat tgggttgaat
    57841 cagctcaact tgtctatcaa tttccaacta agttcactat taaggtcaag gaatatgata
    57901 ttgtggccta ctatatttct ggtgaaaatc attatcctat tctttccagt ggtcagcttg
    57961 agactagttc tgtgagcctg aacagtttac cagaaactta tttatcagtt ctctttaatg
    58021 atagtgaaca aatcaaggtt tttgtctcag aacttgctca aattagccca gaactcaagg
    58081 cggctatcca aaaggtggaa ttagccccaa gcaaggtgac atccgattta attcgattga
    58141 ctatgaatga tttggacgaa gtcttggttc cgctttctga aatgagcaag aaactgcctt
    58201 attatagtaa gattaagcca caattgtcag aaccgagtgt gattgacatg gaagctggaa
    58261 tttacagtta cactgtggcg gataaattaa ttatggaagc tgaggaaaaa gccaaacaag
    58321 aggctaagga agctgagaaa aaacaagaag aagaacagaa aaaacaagag gaagagagca
    58381 atcgaaacca aacgacccag cgctcatcgc gtcgctaggt ttaccttttc tcttatagtt
    58441 ctttagtgac catgttttta cttgacaagt gctagtagaa ataatagaat agtaaaaaac
    58501 ctttaaagca gtccagagag gcagctaagg ttagacggtg aaagggtgga gactacccat
    58561 ttttcgtgga accttgctgt tggcaggttc cttttttcgt ggcttctgtt ggccagactc
    58621 tctcactagt aaaggtaaaa ggagaaacct atgcgagaac atcgtccagt cattgctctt
    58681 gattttccta gttttgaggc ggtcaaggaa tttttagctc ttttcccagc agaagaaagc
    58741 ctttatctca aggtagggat ggagctttat tacgcagcgg ggcctgagat tgtgtcctac
    58801 ttaaaaggtt tgggtcatag tgtctttttg gatctcaaac ttcatgacat tcctaataca
    58861 gtcaagtcag ccatgaaggt cttgtctcag cttggtgtcg atatgactaa tgtccatgcg
    58921 gctggtggtg tagagatgat gaaggcggcg cgtgaaggcc ttgggagtca agctaaattg
    58981 atcgctgtaa ctcagctcac atcaacgtca gaagctcaga tgcaggagtt tcaaaatatc
    59041 caaaccagtc tgcaagagtc tgtgattcac tatgccaaga agacagctga agctggcttg
    59101 gatggtgttg tttgctcggc tcaggaagta caagtcatca agcaggctac caatccagat
    59161 tttatctgtc tgacaccagg gattcgtcca gctggtgctg cagttggaga tcaaaaacga
    59221 gtcatgacac ctgctgatgc ctatcaaatc ggcagtgact atatcgtagt gggacgtccc
    59281 attacccaag ctgaggatcc tgttgcagct tatcatacca tcaaggatga atggacacag
    59341 gactggaatt aaagaactag attagaaaaa taaaaggaga ataccatgac acttgctaaa
    59401 gatatcgcta gccacctctt gaaaatccaa gccgtttacc tcaaaccaga ggaacccttc
    59461 acttgggcat ctggtatcaa gtcaccgatt tacactgata atcgtgtgac actagcctat
    59521 ccagaaactc gtaccctaat tgaaaatggt tttgtggaag ctatcaaaga agcctttcct
    59581 gaagtagaag tgattgcagg aactgcaaca gcagggattc cacacggagc cattattgct
    59641 gataagatgg acttgccttt tgcctacatc cgtagcaaac caaaagacca cggagctggt
    59701 aatcaaatcg aaggtcgcgt agctcaaggt caaaaaatgg tagtggttga agaccttatt
    59761 tcaacgggtg gttcagttct tgaagctgta gcagcagcca agcgagaagg agcagatgtg
    59821 cttggagttg tagcgatttt cagctaccaa ttgccaaaag cagataagaa ctttgcagat
    59881 gctggtgtta aacttgtgac gctttcaaac tatagcgagc ttatccatct agcccaagaa
    59941 gaaggttaca tcacgccaga gggccttgat cttctaaaac gctttaaaga agaccaagaa
    60001 aattggcaag aaggttaggt cagtaagata aagagagatg aggctaccga gcctctttta
    60061 tcattttatt taaaatatga caatatttta aataaaatga ttgacaacgc tttcttttgt
    60121 tgatataatg aaaatgtaat atgtatcaaa ttgatcaatc aactatcttg tttatcactt
    60181 cttaggagga cgatgtcatg aaaagaagaa aaatatattc cttttttgcg tagttacaat
    60241 tgcatctagt ttgtttctcc ttacagtttt agctagacag attggagatt atgatttaac
    60301 gttgccgcgt tggggttcgg atacaactag tgagcttgag aaagaaaacg cctctgctgg
    60361 aattaataat aatgacagca ctggtggcgg taaaaggtta aatacctcta ttcgtagcgc
    60421 ctatagtggg tcagatatta ccccggtata ttcattgggg tctggctcta ggattgtcat
    60481 gtactataat ggaggtggtg acaattatat tggttctggt actagattag ctatggcgcc
    60541 acaatttgga aatcatgtaa gaattcatac ttcaggttct tggaatccag attcttatta
    60601 acttacttgt cagagtaagc cttagagatg gttgattgtg ggtgtagcat gaaaaaagaa
    60661 tgctacaccc tatttttatt ataaggagga gtaaggatgg aatttttcat ttgtaatctt
    60721 gtacgagtcg ttcaatcacc tcgattttat atgtctttat ttttgaccct tctttgcatg
    60781 agtttaggaa atttccttgc tttcaatggt atttataaaa ttgaaggttt atcgattttt
    60841 tttgccgctt cttctattcg aggattttca ccgattagcc tagtagctgc acttatctgt
    60901 acactgccct attctagtca gataatagag gatgctgaga gtcattttct aacagcacaa
    60961 ttgtgtcgaa tttctaaaaa gaagtatctg gctattgtgg gtagtactgt aattatttct
    61021 tcttttctag tcttttttct cccctattta ttattattag gaattaatct tttagtgact
    61081 ccttatcagg aaatttatat tggagattat agtggtgcct taaaagaatt atttgattcc
    61141 aatcagtttc tctatagtct tgtaacgact ctctggtatg gagtttgggg cgctgtgttc
    61201 tctatttttg gactagctag tgctttgcta gtgaagaaaa aaataggagc tattttcatc
    61261 ccagttgcct atatgatggt tggtggtatt ttttgggcta ttttagggct atcttactta
    61321 gaacctgtga caacattagc tttgggatat cagaaagata tcagtctttc cttagttagt
    61381 gggcatcttg cttttatttt atttgttagt tgtttggttg tttatggtac attttttcta
    61441 cattcagagg actacgtata atgaaacaat ttgttcaatt ttacaaaaaa gattttttat
    61501 cagtattggt ttattttata ttactgctat cctgtgtttt atctagtaca gtatatttat
    61561 tgcgctgtcg ccaatattca atccatccaa atgtattaga atggatctta gttttacttc
    61621 aagatatgac gactggagta tattgctttc cgttcacata tatattgttc tttttttatt
    61681 tgatgaataa ctattttaat aggttggagt gtcgcattcg tctgaaatca attaagcact
    61741 ttaccagttt tagtttcaaa ttagcagctc ttagtacggg gatttggacg gcgactttat
    61801 ttttattgat ttttctaatt gcatttagta atggttttag cttctctttg gagataaagg
    61861 aggttgattt tttaagagaa ttttatggta taagtattgc aaacaatgct agtttcttta
    61921 taggattttt ttctcttata tagcatacta tttcttttta tccttactta ctattagcag
    61981 tttttcttgg tttaaaaaat caaacatgag cttagtattt ctgtttactt ttttatttgt
    62041 agaatcctta ttctggattt atcagttgga caatgggata attggattat tgccaatttt
    62101 tcagtatatg gtaaattcca atccgtatgc attgatttat tggcttacat tactatctat
    62161 cataattcca ttgactgtat tttctgttca tagaaactgg aggagagtgt aaaagttgga
    62221 aatgggaaag ttaagtagtc acatgtggag gttgaatcag ataatctata ccaagtactt
    62281 ttggggttat gttctttttt ggatattgat ttgtttagga ttatggtatt ggttagaagg
    62341 aaatgataga cttgttatag aaattttaaa agggcctaat ctgagtcaaa actctttttt
    62401 agtcttatct atatggttgc ttcattggtt tattattcat acattttttc tagcagttgt
    62461 atatcgtaga agagcatccg atttctttat ggaagtgatt cgattttctt ctattaagct
    62521 ctggattagg tatcagattt ggacctgttt tctttatgga ctcattttaa tcatggtaaa
    62581 agttctagtg attcaattta tgttacagtt accaaactgg gatataggag ttttgtttat
    62641 agttgattct ttgaatgctt gtgtgttagt cttgttttgc tttatgttat acgcactagg
    62701 agcgaatgta caaatgaact ttgcttgcgt tagtttcttt ttactcatga ttgtgtttgg
    62761 tggtctattt gtaggaaatc gaactaatta tctattttat attttgaatc gagggaatgg
    62821 agatatagga cgagatttat ttcttcagtt gctattttta gtctttcttt ttaaaagtat
    62881 tttctatttc actcgtcaaa agaggaggtt tatagaatga atgaaataat catattaaaa
    62941 aatattgagt tgaaattaaa aaaaacatgt gtttttcaaa accttaattt tagttgtaaa
    63001 cagggggaaa ttataggaat tactggtgcg aatggctcag ggaaaagtgt attgtttaaa
    63061 ttaatagctg gtttatatag tccgtcttat ggagaagtgt taatcaatgg ggaaaatatt
    63121 gttcctgaga gaaaaattcc agctaatttg ggagctttga ttgaagaacc tggttttata
    63181 aattattata gtggctttaa gaatttacaa tatttggcaa gcatacgagg agtagttggt
    63241 aatcaggaaa tcaatgatac actgaaaata gttggtctat atgagcaaaa agaccagaaa
    63301 gttaaaactt attcgctagg tatgaggaaa aagctaggga ttgctcaagc aattatggag
    63361 aatccctcta ttcttttact agatgaacct atgaatgcct tggataaatc aagtgtagaa
    63421 aatatgagaa cattgtttag aaagctctct agtgaaaaag ggacaacaat tttgattgct
    63481 agtcatagtg aagaggatat tcgtatctta tgtgataaag tatatgcaat agaagataaa
    63541 gtatgtacac tgtgttcaga ttgaacatct tagatagact caggatgtta taggtaaaat
    63601 cttaaaaagg gattggagct taaaatccag tcccttttaa gagttaatgg ccaccttcaa
    63661 caaccaggtc atctgcttta gcagcgtcac cgtaggttgg gtgaagtgtt ttttcatagg
    63721 ccttgtggaa gaagttttcc ttgcctaatt tttcaatatc tttattgatg aagtctagca
    63781 attcttggtt gcctttttga actgctgccg caatggtatc gggatcaccg agggaagtaa
    63841 ttcctacttc aaatccttta ttttcaagcg cccaagctag aacttccgta ttgtcagttg
    63901 aaaaggcatc tccacgtccg tcaagaagag cttggtaaga gtcactgtat tggtcgtatt
    63961 tttggagttt gatttctgga tgattctttt caaaataagt ctcagcagtc gttccttttg
    64021 tgacaattaa ggttttacct tcaagttgtt tgacgtctgt aatgagacca gtcttaggtg
    64081 atacgacacc cagagaaact ttcatatatg gaagggcaaa atcaacttgt ttcttacgtt
    64141 cgtcagttac tgtaaagtta gcaagagtaa tatctacctt gtttgaaatc aagtattccg
    64201 cacggttggc agcatcgact gaaatgtatt taaccttgac accaaggtct ttagctagtt
    64261 ggttccctag ttcaatatcg tagccttggt aagaaccatc attgtcaacg tagccaaacg
    64321 gttttttatc tccaaacacg gcgattcgca gttcaccgcc tttttttgat ttcatcgata
    64381 gtgcgagctt tggcagttgt ttttccagag gatgaaccag cgtttccacc tgagctacaa
    64441 gcagtgataa agataagggc aaaggcaagt gctaaaacag ttaagagtgg tttgaatagt
    64501 ttcataagaa tctcctttat agatatgagc caaattggct aaagtcaaag acgtttaaaa
    64561 attcctgggc tcgtttggtt tgcggattgg taaagaaggc ttgagctgtt ccttcttcag
    64621 cgattttccc ttggtcgagg aagataatcc ggtcagcaat ggcttgggca aactgcattt
    64681 cgtgggttac taaaatcatg gtacggcctt cttgggccaa atcattgata agttccagca
    64741 cctcacgcac catttctgga tccagcgaag cagtcacctc gtcaaaaagg atgatttctg
    64801 gatgcattag gagggcacgg acaattgcaa cacgttgctt ctgtccacca gataattgac
    64861 gggcaaagct atgttgttta tccagcaaac cgacacgatc tagtaattgc aaagcttctt
    64921 ccgttacttc tttcttgtcc cttccttgag ttttgatagg gcctaggatg aggttttgta
    64981 agacatccag atggggaaag agttcataac tttgaaagac catgccaatc ttttggcgaa
    65041 ctaggtgaaa atttttttta ttttcaacga tagactgacc atccagaaaa atatctccac
    65101 cttgaatact ttctaagccg ttgaggcaac gaaggagggt acttttccca caaccagatg
    65161 gccctaggat gacaacaact tccccttttt tgatttctag agaaagtcct tggaggatgg
    65221 gattgtctcc gaaggatttt tttagttcct tgatttctaa gatagtttca gacatttagt
    65281 ttctccaatg tttttctaag tgagtggata gtttggaaat agggtagcaa actgcgaaat
    65341 ataagactag aatggttcca taaatccaaa atgaagcagt tgggatggtc aggcgattgc
    65401 tatcgatgat ttgttgtcca actttggtca cttccacaac cccaatcaaa acaactaatg
    65461 aagtggtttt aatcatccga gtgacaagat tgatagcctg cggtagcagt cttctcaaga
    65521 cttgtgggat gatgatgtgg tagtaaagtt gaacattagt caagccgagt gcctgtccac
    65581 tttcaaactg atgtttaggg agagaagtga tagctccacg taccaagtct cccatttcag
    65641 ctgttcccca gagggtaaaa acgataatag ctgaagtctc acctgagata ttgatattaa
    65701 agtttcgagc caagccaaag taaacgatga agagtagcac cagctggggc atgatacgga
    65761 taaattccag atacaatcgt gttaaaaatc gtatgattct agaatgggag gtcatgatga
    65821 ttcccatgac tgttccgaac atcatggata agaggacaga caggatggat atcccaatcg
    65881 taacgcccaa tccctgtaag attctcagga gattatttcc ttgaaagagt acttggattc
    65941 ccgaatcctg catggcggag cctcctttct atccagctaa agaccagtga gatgggtagc
    66001 agcatgatca gataagcaac taccaacata gctagcgcaa tgtctgtctc atagtagaga
    66061 ccaatcaaat ccttggcgac gtacatgagg tcggccaaag ccactgctga gaaaacagag
    66121 gtttccttga taaggaaaat gacattggca ctaaaggagg ggagtgccac cgctgttgct
    66181 tgcggaagaa ccacatagta aaagacctgt agaggtgtca gaccaatagc gaggccaatc
    66241 tcctgctggg tttgactgat ggcttccagc ccgcttcgga aagattctgc catataggag
    66301 tctcctaaaa agacaagccc aagcgttgca cagacttctg aagataggac aatcccgatt
    66361 cggggaagac cgaagtagag aaagaagagt tgaatcaaaa ggggcgtatt acgtgacaat
    66421 tcaatgtagg ctgtcgctac ttgcgacaaa acaaggattc gataatgtcg gatgatacta
    66481 acgattaaac cgagcagaaa ggatcccaaa attccccaaa ctgcaatatg caaggtcaga
    66541 aagaatgcct tttgatatag tggtagatat tgttcaacaa tggatcaatc caaaaataga
    66601 acctcccatc tagaaataat acagttattg tagcacttaa aatcttcttt ggataatatc
    66661 tattttttat tgccgttata aggattttta tcatagacat aaaatttctg aaatttccaa
    66721 acaaaatatt ttaaaagttt tgaaaaagag ttaagatatt tttgtaatac acaaagtaaa
    66781 cgcttactta ttaaggagga cattttatgt catacaaaac aagcaatgca gaaggtcatg
    66841 tagatttcat caatacctat gatttggagc caatggcgca acaagttatt cctaaagcag
    66901 catttggcta tatcgctagt ggggcgggag atactttcac ttctttccag tgattttagc
    66961 gtcaggttct ttttagtttt taaagattat ccgtgaattt cttgcttatt tatgataaaa
    67021 tgggagtatc gcaaaaaatg actcatcgta ttcaattttg agtaaaacta ggaggatccc
    67081 atgtctacag aacatatgga agaactaaat gaccagcaga tcgttcgccg tgaaaaaatg
    67141 gctgcgctcc gcgaacaagg aatcgatcct ttcggaaaac gttttgaacg tactgcaaat
    67201 tcacaagaat taaaagataa atataccaac ctcgataaag aacaattaca cgataaaaac
    67261 gaaacagcta ctatcgcagg acgcttggta accaaacgtg gtaaaggaaa agttggtttt
    67321 gcccaccttc aagaccgcga aggccagatt cagatctacg ttcgtaagga tgctgtcggt
    67381 gaagaaaact acgaaatctt caaaaaagca gaccttggtg acttccttgg tgtcgaaggt
    67441 gaagtgatgc gtacggatat gggagaactc tctatcaagg caacccacat cacacacttg
    67501 tctaaggctc ttcgtcctct tcctgagaaa ttccatggtt tgacagacgt tgaaacaatt
    67561 taccgtaaac gttaccttga cttgatttct aatcgtgaaa gctttgaacg ctttgtcact
    67621 cgttcaaaaa tcatctctga aatccgtcgt taccttgacc aaaaaggatt ccttgaagtg
    67681 gaaacacctg ttcttcataa tgaagccggt ggtgctgctg cccgtccatt tatcacccac
    67741 cacaatgccc aaaacattga catggtgctt cgtatcgcga ctgagcttca cttaaaacgc
    67801 cttatcgtgg gtggtatgga acgtgtctat gaaattggcc gtatcttccg taacgaagga
    67861 atggacgcta ctcataaccc tgagttcact tctatcgaag tttaccaagc ttatgcagac
    67921 ttccaagaca tcatggactt gactgaaggc attatccaac acgctgctaa atcagtcaaa
    67981 ggtgatggcc cagtcaacta ccaaggtact gaaatcaaga ttaacgaacc atttaagcgt
    68041 gttcatatgg tggatgctat cagagaaatt actggtgtcg atttctggca agacatgact
    68101 ttggaagaag ctaaagctat cgctgctgag aagaaagttc cagttgagaa acactacact
    68161 gaggttggtc acatcatcaa tgccttcttt gaagagtttg ttgaagaaac tttaatccaa
    68221 ccaacctttg tctatggaca tccagtagct gtatctccac tcgctaagaa aaatcctgaa
    68281 gaccaacgct ttactgaccg tttcgagctc tttatcatga ctaaggagta cggtaatgcc
    68341 tttactgagt tgaacgaccc aatcgaccaa cttagccgtt ttgaagccca agctaaagcc
    68401 aaagaacttg gtgatgatga agcgacagga atcgactatg actacattga agctcttgaa
    68461 tacggtatgc caccaacagg tggtttggga atcggtatcg accgtctctg catgctcctc
    68521 actgatacaa caactatccg tgatgtattg ctcttcccaa caatgaaata aattcttatc
    68581 ctctggctct taccagggga ttttttgatt caaaaagaga ctgaatttaa ggagaaaatg
    68641 aagtgtagta tattgaagtt gaaatagtac actttgattt ctaagacatt gttagaaatt
    68701 ggtttaaatt ccctaagcaa tttgtgcatg ttttatttca ttttacgata gtacgctgaa
    68761 actgttcaaa aagtactaga aattgacttg gattccccaa ttgatttgtt cagattcact
    68821 ataaataaaa aattaataag tgggatagga agttagcgtc aactaggata gtatcttgct
    68881 taaacagtat atatgggact gatataagtc cataggtcct attagaggat gttctggtgt
    68941 cttattcact tgttttttta tagtattagt agatagaatc cgcaaataaa aaagtagttc
    69001 aaatgcctgg cagcaaaaaa tctcaacgat tcacttaata tagactaagg tttagagttt
    69061 aaggaaagta gggctagtat attgtatgaa aaaataagat ggtttttaag caaaactctt
    69121 gaaaatgatt gaaaaaagag ttattatagt tgtgtagtaa aaagcaaacg cttacttaat
    69181 caaggagggc attttatgtc atacaaaaca agcaatgcag aaggtcatgt agacttcatc
    69241 aatacctatg atttggagcc aatggcgcaa caagttattc ctaaagcagc atttggctat
    69301 atcgctagtg gggcggaaga tactttcact ttaagagaga atatccgcgc ctttaaccac
    69361 aaactcatcg ttcctcatac actttgcgat gttgaaaatc caagtacaga gattgaattt
    69421 gcaggtgaaa aactatcttc accaatcatt atggcgcctg ttgcggccca taaattagcg
    69481 aatgaacagg gggaagtggc gactgcgcgt ggtgtgcatg agtttggttc tctttataca
    69541 accagttctt actctactgt tgaccttcca gagatttctg aagcccttca agggacaccc
    69601 cattggttcc aattttactt tagtaaggat gacggtatca accgccacat catggatcgt
    69661 gtgaaggctg aaggttataa agcgattgtc ttgacggcag atgctactgt aggggggaat
    69721 cgtgaagtgg ataagcgtaa tggttttgtc ttcccagttg gcatgccgat tgttgaagaa
    69781 tacctgccag aaggtgctgg taaatcaatg gactttgttt acaaatcagc taaacaacgc
    69841 ttgtctccac gtgatgtaga atttatcgct gaatactcag gacttcctgt gtatgtcaag
    69901 ggaccacaat gccgtgagga cgttgaacgt tcgcttgctg caggagcttc tggtatctgg
    69961 gtaaccaacc acggtggtcg tcaaatcgac ggtggaccag ctgcctttga ctcgcttcaa
    70021 gaagtggcag aagcagttga taaacgtgtg ccaattgtct ttgactctgg tgttcgtcgt
    70081 ggtcaacatg tctttaaagc cttggcttca ggagcagact tggtagctat tggtcgcccg
    70141 gttatctatg gcttggctct cggcggtagt gttggtgtgc gtcaagtctt tgaacacttg
    70201 aatgcggaat tgaagacagt tatgcagttg tctggaactc agactattga agatgttaaa
    70261 cacttcaaac tccgtcacaa cccatacaac ccaactttcc cagttgaccc tcgtgactta
    70321 agattgtatt gataaaagag attgcctcca ctgaatgtgg aggtttttct tcgtgtattg
    70381 gaagaataaa tcgctatcga aaaccatagt aaaatggaat aaaaacagga caaatcaatc
    70441 aggacagtta aatcgatttt taacaatgtt ttagaagtag atgtgtacta ttctagtttc
    70501 aatctactat atataaagat atttttcggt caaatatctt gctagggctt tcattttttg
    70561 ctatactggt tcagtaatta aataatagag acatttgggg tgctttaagc tgagatgata
    70621 cccattgaac ctgatacagt taagactggc gaagggaaat gtgaaacgtt ttttcgtatg
    70681 acgaaatgaa cgatctaatc ttgtaagtca actctaattc ttgattgtaa ttggagtttt
    70741 ttgtttatat aaactggata ggcttgttta gttagctctc tgcaaatgct ctcgatgtgc
    70801 tttaaaagga tcaagtggaa ttacgatttt gcttgatatt tcttggtgtt ttattaatta
    70861 ctaacaagta aagagaggag aagtaaatat ggaaacacaa gactatgcat ttcagccagg
    70921 tttgactgtt ggagaattat taaaaagcag tcagaaggat tggcaggctg caatcaatca
    70981 tcgttttgtt aaggaacttt ttgcggggac aattgagaat aaggtcttaa aggactatct
    71041 gattcaagat tatcacttct ttgatgcctt cttatccatg ctgggtgcct gcgtagctca
    71101 cgcagataaa cttgaatcca agcttcgttt tgccaagcaa ctaggctttc ttgaagcaga
    71161 tgaagatggt tatttccaaa aggcttttaa agagttaaaa gtagcagaga atgactatct
    71221 agaagtgact ttgcaccctg taacaaaagc ctttcaggat ctaatgtatt cggcagtggc
    71281 ttcatcagac tatgcccatc ttttgattat gctggtcatt gcagaaggtc tctatttaga
    71341 ctggggttct aaagatttgg ctttacctga agtctatatt cattcggaat ggatcaatct
    71401 ccacagaggt cctttctttg cagagtgggt tcaatttctg gttgacgaac tcaatcgtgt
    71461 cggtaaaaat cgagaagatt tgacagaact tcagcaacgc tggaatcaag cagtcgcttt
    71521 agaattagct ttttttgata ttggttacga tgtctagaga aggctcatga tatttacaaa
    71581 tttgatgagg taagactctt cgaaaatctc ttcaaaccac gtcagttcta tccacaacct
    71641 caaaacagtg ttttgagcaa cctgcggtta gcctcctagt ttgctctttg attttcattg
    71701 agtataaatc attcaatgta aatgaaaaaa attctcaact aaagataaat cgaaattagt
    71761 agatcgtata aagtgaaaag gaaggatttc aatatgacaa gtttaaaatt attaaaagaa
    71821 aaagcacctt tggtcatttg catcaccaat gatgtagtaa aaaatttcac agcaaatgga
    71881 ttagtagcac tgggcgcctc accagccatg agtgagtttc cagaagattt agaggactta
    71941 ttaaagtatg ctggtggttt attaataaac ataggaacat tgacagatga aaattggaaa
    72001 ttataccaag ctgctctgaa aattgcagag aaatataatg tcccagcagt tttagatcct
    72061 gtagcctgtg gagcaggaga atatagaaaa aaagtagcag atgatttaat caacaattac
    72121 aaactagctg cgattagggg gaatgctgga gagattgcct ctttagtagg aatagatgtg
    72181 gcatctaaag gagtagatag tgcgggagta gataatattg acgagattgc tctagcagca
    72241 aatgagaagt tcaatattcc aatagtagta acaggtgaag tggatgctat tgcggtaaat
    72301 ggagaagtgg taacgattca taatggtagt gccatgatgc caaaagttat tggaactgga
    72361 tgtttattag gagctgtagt agcaagtttt atcggactgg aaaaaggtca agaattaaaa
    72421 tcattagaaa cagcaatgtt agtttacaat atcgctggag aaatggcaga aaaacgtcca
    72481 aatggacatc ttcctgggac atttaaagtt gaatttataa atgccttata cgagattaca
    72541 gatgaagatg taaaggaatt caaaagagtg aagtaagatg tttcataaag aattactaaa
    72601 actatatttt atttgtggaa cgactacttg ccaaggaaaa aatctatata cagtcgttga
    72661 ggaagcctta aaaggtggta taaccttatt tcaatttcga gaaaaaggtg agggtgcttt
    72721 agaaggctta gaaaaacttg agctagctat ccaaattaaa gaactttgta aaaaatacaa
    72781 tgttccattt atcgttaatg acgatataga tttagcaatg gaaattgacg ccgatggcgt
    72841 acatgtaggt caagatgata ttggtgttga tgaaattaga aaattgatgc cagataaaat
    72901 aattggtctt tctataagaa acgaagaaga atttcaacaa tcaaaagttg aatatgtaga
    72961 ttatgtaggt gttgggcctg tatttgatac ccagtcaaaa gatgatgctg gtggtgctat
    73021 aggttatgaa ggtcttgaat tgatgagaaa actattgcca caaatgcctt tagttgcaat
    73081 tggtgggata cagacgaaac atattaaaga cattataaag accaatatgg atggcgtttc
    73141 aatcatttcg gcaatatcgt atgcaaaaaa tatagaaaaa actgttcggg aaatgagtga
    73201 acaatagata tctatccttg gattctaagt aagtaggatt ttcctttttt aaaaagctat
    73261 gtccagattc agcttgaatg gctaattcat caaacaggtc atttgttttt tgcaaaagaa
    73321 agatctgctg tctttgtgag tgcaaggctg tatttccagt tcaatttctt gaactagtat
    73381 aaaatgtgtg ttataataat cacataatta aataataaag acatttgggg tgctttaggc
    73441 tgagatgata cccattgaac ctgatacagt taagactggc gaagggaaat gtgaaatgtt
    73501 tttttcgtat gtcgaaaaga actgtctaat cttgtaagct gaactctaat tcgtatctgt
    73561 aattagagtt ttttctttta cgaaactgga tgaagatgat atagtagatt gaaataagat
    73621 gcgaacaaat caattagaaa attcaaatta atttctagaa atattttagc attcttgtgt
    73681 actgttctaa attcagtctg ctatacaaag tatttaggtc ggtcttcttg agtgccccac
    73741 ttttctttaa aaaaaggagt tttttatgtt gaaaaaatgg cagttaaaag atgttatctt
    73801 gcttgctttc ttgtctatct tttttggtgg ggttttcgtt ggttcaggat atgtgtataa
    73861 tattctcagt ctactcttaa cacctcttgg tttgcaggcc tttgccaatg aaatcctctt
    73921 cggtctctgg tgtatggctg cgcccattgc tgccatcttt gttccgagag tcggaagtgc
    73981 aacgattgga gaagtgctag ctgcgcttgc tgaagtcctt tatggtagcc aatttggtct
    74041 aggagctctt ttgtctggct tggttcaagg tttgggaagt gaatttggtt ttatcgtaac
    74101 taagaatcgc tatgaaagtt ggctctctct aactgctaat agtattggga ttacgcttgt
    74161 tagctttgtc tatgaataca ttaagttagg ttactacgcc ttttcccttc cgtttgtcct
    74221 ttccttactt gtggtacgtt ttatttctgt ttatttcttc tgtaccatct tggttcgtgc
    74281 cattgtcaaa ctctatcatc agtttgcaac tggaggaaaa gcatagatgg gtctggaact
    74341 acgagcgatt cagtccccaa tcttctctga gccgtttgat tttacttttc atgcgcaagc
    74401 ctttaccttg ttagttggga gtagtgggtc tggaaaatcc agcctctttc aaatgattgc
    74461 ccaagtcagt tctcttccct atagtggtca agtcctgata gatgggagcg aggtcagtca
    74521 actttctatc atcgcacgtg tccagaaggt tggcattctc tttcaaaatc ccaatcatca
    74581 atttaccatg gagagcttgt ttgaggagct gattttcacc ttggagaata tcggctatca
    74641 ccttcaggaa attgattcta aaatagcaga ggttgtccag caatgtcgtt gcgaggcaat
    74701 cttacaccgt cccattcatc acctatcagg tggggaaaag caaaaagcag cgctggctgt
    74761 cctctttgcc atgaatccta gggtctatct cttggatgaa ccttttgctt ccattgaccg
    74821 caagagcaga atcgagatat tggagattct aaaagagttg gctcttgatg gaaagacagt
    74881 tattttgtgc gaccatgatt tatctgacta taaagcctat atcgaccata tggttgagct
    74941 aagagacgga aaactaaggg aagtgtttca aatcccttcc tatgagatga cacaggttgc
    75001 ttcaaaggaa gttgcttcta gcccggaact attccatatg gatagaacga cttgtgagtt
    75061 tggaaatcgc cccctctttt caattgctga tttcacattc tatcaaggga tttcctgtat
    75121 cctgggtgac aatggtgtcg ggaaatcaac cctctttcgg tctattcttc aatttcaaaa
    75181 gtataagggg cgcattgcat ggaagggttc ggtcctgaaa aagaaaaaga gtttgtatcg
    75241 tgatctgact ggtgttgttc aggaagctga gaagcagttt atccgagtca gtctgcgaga
    75301 ggagcttcaa ttagatggac ctgattctga aagaaatcag cggatttttc aagctttacg
    75361 atattttgat ttggagcagg cagtcgataa gagtccctat caattaagtg gtggtcagca
    75421 aaaaattctt cagctcctga ccatcttgac cagtaaggct tccgtgatct tgctagatga
    75481 accttttgca ggtttggatg atagagcctg ccattatttt tgcaagtgga ttgtggagga
    75541 gaggaatcaa ggaagaagtt ttctgctcat tagtcatcgt ttagaccctt tgatttctgt
    75601 ggttgattat tggattgaga tgactagtca gggtcttcgg catgtgaaag aagtgaccat
    75661 taccaaacca cttacatctc agagtagcaa tacccaaggg gaggtgagat agtatggtca
    75721 aagtagcaac ccagacaccg attatcagtc tcttcttgct gattttatcc ttggaaacat
    75781 ctttcattcc ttcgattgct ctgaatcttt cggtagtcgc attttgtatt ctctttatgc
    75841 tctattaccg tcgatttaaa atgttagctt ggatgatcat acttgccatt ttaccatctt
    75901 ttgccaacta ctgggcagtt cagttacacg gagatgcttc acaggcagtc atgcttggaa
    75961 cgagggcctt tgtgacagtt tgtatcggcc ttgtctttgt ttcctctatt tcactaaaag
    76021 agcttctctt gtacttggct caaaaggggc tatcacgctc ttggtcctat gccttgattg
    76081 tggtattcaa ttcttttcct ctcattcagc aagaaatcaa gtccctcaaa gaagcttgcc
    76141 tattacgtgg tcaagaacta catttttggt cgcccttgat ttacagtaag gttctgatga
    76201 cagtctttag gtggcgccat ctttacctga gagctctatc tgctcacgga tatgacgaac
    76261 atgcacagtt gaagaatagc tatcggactt tttatattcc taaaaaaaca aaattaatct
    76321 acctgctttt ctttttattg cttcaaacca gtctattttt ataaaggagt tattatggaa
    76381 tttacagata ttgcgatgga attatccaag aaagcttggc aggcttcctt tcatcatccc
    76441 tttattttac aattacaaga ggggaattta gaacctgcca ttttccgcta ttacctgatt
    76501 caggatgcct actatctgaa ggctttctca gaaatctatc atcttttggc tgataagact
    76561 tcaaaccaag agatgaaaag actcttgaaa caaaatgctc agggtttagt ggagggtgag
    76621 ttatttattc gccaacaatt tttcaaggaa ttggaaatca gcgaccagga aatggagcaa
    76681 catccaatcg ctccaacctg ttatcattac atttctcata tttataggca atttgcagaa
    76741 ccgaacttag ccatcgcttt tgcaagcttg cttccttgtc cttggttata ccatgatata
    76801 ggcaaatcac ttaatcttaa accatcacca aatcctctct atcaacaatg gattgaaact
    76861 tatattacgg atgagttaga gcaacagatc agagaggagg gagcactggt caatcagctc
    76921 tatcgagaaa gtgatgagac agataagcaa aaaatgctag atgccttcca catcagtgtt
    76981 catatggaag ccaagttttg ggagatggct taccaacacc agacatggaa gagcgattta
    77041 cagtctttag aaaaaggaga agaatagaaa catgagaaag caccaactac aagttcacaa
    77101 attgaccatt ttatctatga tgattgccct tgatgtagtc cttacaccta tctttcggat
    77161 tgagggaatg gcaccgatgt ccagtgtagt caatattcta gcgggaatca tgatgggacc
    77221 tgtttatgcc ttggctatgg ctacagtgac agcctttatc cgtatgacga ctcaagggat
    77281 tccgccttta gctctcacag gagcgacttt tggagccctt ctagcaggtc tcttttataa
    77341 gtacggtcga aaattttact tttctgcctt gggagaaatt gtgggaacag gtattattgg
    77401 ttctattgtt tcctatcctg ttatggtact ctttacagga tcagctgcta agcttagctg
    77461 gtttatctac acgcctcgat ttttcggagc aaccttgatt ggtacagcga tttcctttat
    77521 tgcctttcga tttttaatca agcaggaatt ctttaaaaaa gtgcagggat atttctttag
    77581 tgaaaggata gactgatgca ggaatttaca aatccctttc ctataggctc tagttccctc
    77641 attcactgta tgaccaatga gatttcttgt gagatgctgg caaatgggat tttggctctg
    77701 ggatgcaaac ctgtcatggc agatgatccc cgtgaggttc ttgattttac taagcaaagt
    77761 caggctctct tcatcaattt ggggcatttg tcagctgaga aggagaaagc aatccgtata
    77821 gcagcttctt atgcagctca agtttgtctc ccaatggtag tagatgcggt tggcgtaaca
    77881 gcttcatcca ttcgtaagag cttagtcaga gaccttttag actatagacc tacggtcctt
    77941 aaaggaaaca tgtcagaaat tcgaagtctt gttggattaa agcaccacgg cgttggggtc
    78001 gatgcgagtg ctaaagatca agaaacggag gatttgcttc aagtcttgaa agactggtgt
    78061 cagacctatc atggtatgtc tttcttagtc acaggtccca aggacctcgt cgtttcgaaa
    78121 aatcaggtcg ctgtactggg aaatggctgt gcagaattag actggataac agggacagga
    78181 gatttggttg gagccttaac agccgttttt ctcagccaag gaaagactgg ttttgaagct
    78241 tcttgcttag cagtctctta tctcaatatc gctgctgaga aaatagttgt tcaaggaatg
    78301 ggattggaag aatttcgtta ccaagtactc aatcagcttt cgctcctaag aagagatgaa
    78361 aattggctag ataccatcaa aggagaggtt tatgaataga gaagcactta gactatatct
    78421 ggtaaccaat cgctatcaag attccgtgga aagctttctt gcaaaagttg agacggcctg
    78481 ccgttcaggg gttaccatag tccaattgcg agaaaaaaat ctcacaacca atcaatatta
    78541 tcaactggca aaacaagtca aggaaataac agatgcttat caggtaccct tgataatcga
    78601 tgatcggttg gatgtttgtc ttgcggttga tgctgctggt ctgcatattg gagatgacga
    78661 actcccagtt tcggttgccc gacaagtctt gggtcctgaa aaaatcctcg gtgtcaccgc
    78721 taaaacggtt aaaagagctc tggaagcgga gaaatcaggt gcagattact tggggacagg
    78781 agccattttt ccgacaacca ccaaggaaaa tgcacccatc accctgattt caaccttgaa
    78841 aacaatttgc caaacggttg ccattccaat agttgctatt ggtggcttga cttcggagaa
    78901 tattgatcag cttatgggca ctggcatagc tggtgtagct gttgtacgtg atttgatgca
    78961 agcagaagat attgaggcaa aaacgcaagc ctttttaaca aagttgcatg acattctttc
    79021 ctaattaata ctcaatgaaa atcaaagagt aaactagaaa gctagtcgca ggttgctcaa
    79081 agtactgcct tgaggtttta gataagactg acgaagtcag ctcaaaacag tgttttgaag
    79141 ttgcagatgg aagctgacgt agtttgaaga gattttcgaa gagtataaaa actctctaat
    79201 tcccttaaag tgggaactag agagtttttt ttcttaatct ttaaaagttg tatggttgac
    79261 tggaccagaa ccatgaccga gttgaggggc atcttgaata gcttttgtga taaaggcctt
    79321 ggccttatca actgcctggt aaagactctt gcccttggct agttcagcag taatcactgc
    79381 agcaaaggta catccagtac catgggtgtg acaggtttga attcgtgggc tttcccagac
    79441 aaattgttca ttcttggtaa agaggaaatc tttagcacca cctttgagat gtccgccttt
    79501 gataaccaca gactgaggac caaattcttt taaaatcagg cgaccagcac gctgcatgtc
    79561 ttcggggtca tggattgaaa aaccaacaat ctcttctgct tcaggaagat ttggcgtaat
    79621 aatagttgct agaggtagta agtttgtttt gagatagtct ctagcacttg agtcaatcaa
    79681 ggcatctcca cttgtagcaa ccataacagg atcaaggaca tagggacaat ccagtttttt
    79741 aagatagggt tggatgattt ccatgatttc agtagtagcc aacattccag tttttacagc
    79801 ctgaggtgga atatcagaaa agacactctc caattgggct ttcaacattt gaggagaaac
    79861 gtgctcgatt agctgaacac ctctggtatt ttgagcgaca agactggtta caacagccat
    79921 tccatagaca tctctcgctt ggaatgactt taaatctgcc ataatgccag caccaccact
    79981 agggtcagtc cctgcaatgg tcaaagcaac gggtaaataa gtcatctaaa acctcccaac
    80041 caactgaagt ttgtattctt aagaacaagc tagtctgttt tagaaaggca atagaagact
    80101 gctagtcccc attatcattt ccacttccat cagctagcat tacctagatt gagtcagagg
    80161 gatctaacag tcgttaatct cagctttacg cacccctagt ggttgttttc ttttttcttt
    80221 agtatagcat atttttattg tttatatagt aatatttgac tgcaaatcgt ttttcaaatg
    80281 attaaaattc tatttttcga agaaaatatt atttctataa ttgacaaatg tagattttgg
    80341 gagtatactg ttgagtgtaa ttgacaaatg tagattttgg aggtatggta atgcagattt
    80401 cagatgcaga atggcaggtc atgaagatta tttggatgca gggggagcag accagtacag
    80461 atttgattag ggttttggca gagcggtttg actggtccaa gtccacggtt cagacacttt
    80521 tggctcgtct agttgagaaa gagtgtttga ctcggaaaaa agaaggcaag tcctttgttt
    80581 attcagcgct tttaactcta gaccaaagtc gggatttact tgtccaagat atcaaagaca
    80641 aggtttgttc ccgtaggatt aggaatttgt tggctgactt gattgtagaa tgtgaattta
    80701 ctcagactga cttggaagac ttggaagctg tgatttcaga gaagaaatca agtgctgtaa
    80761 cagaagtaag atgtaattgt atgtaaagga gacgtcatgt taaatagtat tgtaaccatt
    80821 atttgtattg cccttatcgc gtttatcttg ttttggtttt tcaaaaagcc tgaaaaatct
    80881 ggacaaaaag cccagcaaaa aaacggatac caagagattc gagtggaagt catgggaggc
    80941 tatactcctg agttgattgt cctcaagaaa tcagtgccag cccgcattgt ctttgaccgc
    81001 aaggatcctt caccatgtct ggatcaaatt gtttttccag attttggtgt acatgcgaac
    81061 ctgccaatgg gggaagagta tgtagtggaa atcacgcctg aacaggctgg agagtttagc
    81121 tttgcttgtg gtatgaacat gatgcacggc aagatgattg tagagtaggt ggagactatg
    81181 acagaaattg tgaaagcaag cttagaaaat ggcattcaaa aaatccgtat ccaagctgaa
    81241 aaaggctatc atccagccca tatccagctt caaaagggaa ttccagctga gattaccttt
    81301 catcgtgcta ctccttcaaa ctgttataag gaaattctgt ttgaagaaga aggtatcttg
    81361 gaaccaatcg gcgtagatga ggagaaagtc attcgtttta cacctcaaga attagggcga
    81421 catgaatttt cttgtggcat gaagatgcaa aagggaagct atacagtcgt tgagaagact
    81481 cgaaaatctc tatctctcct gcaacgtttt tggattacta gtatctgtac tgtgcctctt
    81541 gtgattctca tgattgggat gttggcaggt agcattagtc atcaagtcat gcattgggga
    81601 acctttctag caacaacgcc tattatgtta gttgcaggta agccatatat ccagagtgct
    81661 tgggccagtt ttaaaaagca caatgccaac atggatacct tggttgcgct gggaactcta
    81721 gtggcttatt tctatagcct agttgctctc tttgctggtc tccctgttta cttcgaaagt
    81781 gctggattta tcctcttttt cgttcttttg ggagcagttt ttgaggaaaa aatgagaaaa
    81841 aatacgtccc aagctgtgga gaaattactg gacttgcaag ctaaaaccgc agaagtcttg
    81901 agtgatgata gttatgtcca agttcctttg gaacaagtca aggtaggcga cctgattcga
    81961 gtgcgtcccg gtgaaaagat tgctgttgat ggtgtcgtag tagaaggtgt ctctagtatt
    82021 gacgaatcca tggtgacagg tgagagtctg cctgtggaca agacagttgg agatactgtc
    82081 attggctcaa ccatcaatca tagtggaacg cttgtcttta gagcagaaaa agttggctca
    82141 gagactgttt tggctcagat tgtggatttt gtgaagaaag ctcagacaag tcgtgcgccg
    82201 attcaggact tgacggataa gatttcaggg atttttgtcc cagtagttgt cattttagga
    82261 atcatgacct tttgggtttg gttcgtcttg ctcagggata gtgtggttgt gcttggagct
    82321 agctttgtgt cctctcttct ctacggagtg gcggttttga ttatcgcctg tccttgtgcc
    82381 ttgggacttg caacaccgac agcccttatg gtggggacag gacgtagtgc caagatgggg
    82441 gttctcctca aaaatggaac tgtcttacag gaaatccaga aagttcaaac ccttgtcttt
    82501 gataagaccg ggactttgac ggaagggaaa cctgtggtaa cagatgtcat cggcgacgaa
    82561 gtagaagtgt ttggattggc agcctccttg gaagatgctt ctcaacaccc actggctgag
    82621 gctatcgtta agcgagcgag tgaagctgga cttgagtttc aaactgttga aaattttcag
    82681 gccttgcacg ggaaaggtgt ttcagggcga atcaatggaa aacaagtttt acttggaaat
    82741 gctaaaatgc tggatggcat ggatatttct aatacttatc aagataaact agaagaacta
    82801 gaaaaagaag ctaagacagt tgtgttctta gctgttgaca atgaaatcaa aggcttgctt
    82861 gctttgcaag atattcctaa gaaaaatgct aagctagcca tcagtcagct aaaaaaacgt
    82921 ggtctcggga cagtcatgct gacaggagac aatgctggtg tggcgcgtgc tattgcagat
    82981 caaatcggaa ttgaagaggt cattgcaggc gtcttgccag aagaaaaagc ccatgaaatc
    83041 cataaactgc aacagtcagg taaagtagcc tttgttggtg atgggatcaa tgacgctcct
    83101 gcccttagtg tagcagatgt ggggattgct atgggagctg gaacagatat cgccatcgag
    83161 tcagcagatt tggtgttgac aaccaataat cttttaggag tggtgcgtgc cttcgacatg
    83221 agtaagaaaa cctttcatcg tattctgctc aatcttttct gggcttttat ctacaatgtt
    83281 gtcggaattc cgattgcagc aggagtcttt tcaggtgttg gactggctct caacccagaa
    83341 ttggcaggtc tagccatggc ctttagttct gtatctgttc tgaccagttc ccttctgtta
    83401 aattttagta aaatagacta aaagtaatga ctagattttt ttgttataaa acagaaatga
    83461 cgacactttc aaaactgtat tagaatagag aatagagagt tttgagcaga tttttagaaa
    83521 agtcagcata aatatgatac agtggaatag taaaaaattg gagaacgttt ccaattctat
    83581 gtaatcgtat tctccaagtc taaaaaaatt gaaggagagt tatcattatg actcaaggga
    83641 aaattactgc atctgcagca atgcttaacg tattgaaaac atggggcgta gatacaatct
    83701 acggtatccc atcaggaaca ctcagctcat tgatggacgc tttggctgaa gacaaagata
    83761 tccgcttctt acaagttcgc cacgaagaga caggtgctct tgcagcggtt atgcaagcta
    83821 aattcggcgg ctcaatcggg gttgcagttg gttcaggtgg tccaggtgcg actcacttga
    83881 ttaacggtgt ttacgatgca gctatggata acactccatt cctagcaatc cttggatcac
    83941 gtccagttaa cgaattgaac atggatgctt tccaagagct taaccaaaac ccaatgtaca
    84001 acggtatcgc tgtttacaac aaacgtgtag cttacgctga gcaattgcca aaagtaattg
    84061 acgaagcctg ccgtgctgca gtttctaaaa aaggtccagc tgttgttgaa attccagtaa
    84121 acttcggttt ccaagaaatc gacgaaaact catactacgg ttcaggttca tacgaacgct
    84181 cattcatcgc tcctgctttg aacgaagttg aaatcgacaa agctgttgaa atcttgaaca
    84241 atgctgaacg cccagttatc tatgctggat ttggtggtgt taaagctggt gaagtgatta
    84301 ctgaattgtc acgtaaaatc aaagcaccaa tcatcacaac tggtaaaaac tttgaagctt
    84361 tcgaatggaa ctatgaaggt ttgacaggtt ctgcttatcg tgttggttgg aaaccagcca
    84421 acgaagtggt ctttgaagca gacacagttc ttttccttgg ttcaaacttc ccatttgctg
    84481 aagtttacga agcattcaag aacactgaaa aattcatcca agttgatatc gacccttaca
    84541 aacttggtaa acgtcatgcc cttgacgctt caatccttgg tgatgctggt caagcagcta
    84601 aagctatcct tgacaaagta aacccagttg aatcaactcc atggtggcgt gcaaacgtta
    84661 agaacaacca aaactggcgt gattacatga acaaactcga aggtaaaact gagggtgaat
    84721 tgcaattgta tcaagtttac aatgcaatca acaaacatgc tgatcaagac gctatctact
    84781 caatcgacgt aggtaacact actcaaacat ctactcgtca ccttcacatg acacctaaga
    84841 acatgtggcg tacatctcca ctctttgcga caatgggtat tgcccttcct ggtggtatcg
    84901 ctgctaagaa agacaatcca gatcgccaag tatggaacat catgggtgac ggagcattca
    84961 acatgtgcta cccagacgtt atcacaaacg ttcaatacga ccttccagtt atcaaccttg
    85021 tcttctcaaa tgctgagtac ggcttcatca agaacaaata cgaagataca aacaaacact
    85081 tgtttggtgt agacttcaca aacgctgact acgctaaaat tgcggaagct caaggagctg
    85141 ttggattcac agttgaccgt atcgaagaca tcgatgcagt tgttgcagaa gctgttaaat
    85201 tgaacaaaga aggtaaaact gttgtcatcg atgctcgcat cactcaacac cgtccacttc
    85261 cagtagaagt acttgaattg gatccaaaac ttcactcaga agaagctatc aaagccttca
    85321 aggaaaaata cgaagcagaa gaactcgtac cattccgtct cttcttggaa gaagaaggat
    85381 tgcaatcacg cgcaattaaa taattcctct cgccgaaaat caaatatgaa acttgtagac
    85441 tttattcttt gattttcata gagcagaact ttaaaagatc ggagcaatcc ggtcttttta
    85501 tggaggagag taaatgaatt taaatcaatt agatattatc gtttcaaatg ttccccaagt
    85561 ctgtgctgac ttggagcata ttttggataa aaaggcagat tatgctgatg atggttttgc
    85621 tcagtttacg attggtagtc actgccttat gttgtcacaa aatcatttgg ttcctttgga
    85681 aaactttcag tcaggaatca ttattcatat cgaggttgag gatgtagacc agaactacaa
    85741 acggttgaac gagcttggta taaaggtttt acacggacca actgtaaccg attggggaac
    85801 agagtcctta ttagttcaag gacctgctgg tctagtgctt gatttttatc gtatgaaata
    85861 ggtcgcgtag tcatttgacg ttaaccttag ctatttt
//
LOCUS       DBERCW010000006        64708 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.006, whole genome shotgun sequence.
ACCESSION   DBERCW010000006 DBERCW010000000
VERSION     DBERCW010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 64708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.006"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(20..871)
                     /locus_tag="ACL72M_000524"
     CDS             complement(20..871)
                     /locus_tag="ACL72M_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGS0715700.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            1071..3128
                     /gene="pbp2b"
                     /locus_tag="ACL72M_000525"
     CDS             1071..3128
                     /gene="pbp2b"
                     /locus_tag="ACL72M_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGS0715701.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            3139..3735
                     /gene="recR"
                     /locus_tag="ACL72M_000526"
     CDS             3139..3735
                     /gene="recR"
                     /locus_tag="ACL72M_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGS0715702.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            3911..4954
                     /locus_tag="ACL72M_000527"
     CDS             3911..4954
                     /locus_tag="ACL72M_000527"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGS0715703.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            5038..6411
                     /gene="murF"
                     /locus_tag="ACL72M_000528"
     CDS             5038..6411
                     /gene="murF"
                     /locus_tag="ACL72M_000528"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGS0715704.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            6398..7009
                     /locus_tag="ACL72M_000529"
     CDS             6398..7009
                     /locus_tag="ACL72M_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGS0715705.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            7100..7804
                     /locus_tag="ACL72M_000530"
     CDS             7100..7804
                     /locus_tag="ACL72M_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGS0715706.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            8023..9396
                     /gene="ftsA"
                     /locus_tag="ACL72M_000531"
     CDS             8023..9396
                     /gene="ftsA"
                     /locus_tag="ACL72M_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGS0715707.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            9413..10672
                     /gene="ftsZ"
                     /locus_tag="ACL72M_000532"
     CDS             9413..10672
                     /gene="ftsZ"
                     /locus_tag="ACL72M_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGS0715708.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            10677..11348
                     /locus_tag="ACL72M_000533"
     CDS             10677..11348
                     /locus_tag="ACL72M_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGS0715709.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            11358..11897
                     /locus_tag="ACL72M_000534"
     CDS             11358..11897
                     /locus_tag="ACL72M_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGS0715710.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            11897..12160
                     /locus_tag="ACL72M_000535"
     CDS             11897..12160
                     /locus_tag="ACL72M_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGS0715711.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            12157..12942
                     /locus_tag="ACL72M_000536"
     CDS             12157..12942
                     /locus_tag="ACL72M_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGS0715712.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            12951..13739
                     /gene="divIVA"
                     /locus_tag="ACL72M_000537"
     CDS             12951..13739
                     /gene="divIVA"
                     /locus_tag="ACL72M_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGS0715713.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            14087..16879
                     /gene="ileS"
                     /locus_tag="ACL72M_000538"
     CDS             14087..16879
                     /gene="ileS"
                     /locus_tag="ACL72M_000538"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGS0715714.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            17282..17662
                     /locus_tag="ACL72M_000539"
     CDS             17282..17662
                     /locus_tag="ACL72M_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715715.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            17856..18146
                     /locus_tag="ACL72M_000540"
     CDS             17856..18146
                     /locus_tag="ACL72M_000540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715716.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            18197..18889
                     /locus_tag="ACL72M_000541"
     CDS             18197..18889
                     /locus_tag="ACL72M_000541"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGS0715717.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            18942..21353
                     /locus_tag="ACL72M_000542"
     CDS             18942..21353
                     /locus_tag="ACL72M_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS0715718.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAVRASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            21603..22304
                     /locus_tag="ACL72M_000543"
     CDS             21603..22304
                     /locus_tag="ACL72M_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715719.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANCDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            22306..25014
                     /locus_tag="ACL72M_000544"
     CDS             22306..25014
                     /locus_tag="ACL72M_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS0715720.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGIVVGETQIQFYWTYSLLALVLSWLASVLPVYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSETPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(25110..25601)
                     /gene="tpx"
                     /locus_tag="ACL72M_000545"
     CDS             complement(25110..25601)
                     /gene="tpx"
                     /locus_tag="ACL72M_000545"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGS0715721.1"
                     /translation="MVTFLGNPVSFTGKQLQGGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(25724..26653)
                     /gene="psaA"
                     /locus_tag="ACL72M_000546"
     CDS             complement(25724..26653)
                     /gene="psaA"
                     /locus_tag="ACL72M_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGS0715722.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(26685..27533)
                     /locus_tag="ACL72M_000547"
     CDS             complement(26685..27533)
                     /locus_tag="ACL72M_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGS0715723.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(27530..28252)
                     /locus_tag="ACL72M_000548"
     CDS             complement(27530..28252)
                     /locus_tag="ACL72M_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS0715724.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            28543..30435
                     /gene="pepO"
                     /locus_tag="ACL72M_000549"
     CDS             28543..30435
                     /gene="pepO"
                     /locus_tag="ACL72M_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGS0715725.1"
                     /translation="MTRYQDDFYDAINGKWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(30558..31187)
                     /locus_tag="ACL72M_000550"
     CDS             complement(30558..31187)
                     /locus_tag="ACL72M_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS0715726.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(31527..31769)
                     /locus_tag="ACL72M_000551"
     CDS             complement(31527..31769)
                     /locus_tag="ACL72M_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715727.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            32180..34402
                     /locus_tag="ACL72M_000552"
     CDS             32180..34402
                     /locus_tag="ACL72M_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015968 - stringent response [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HGS0715728.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            34432..34875
                     /gene="dtd"
                     /locus_tag="ACL72M_000553"
     CDS             34432..34875
                     /gene="dtd"
                     /locus_tag="ACL72M_000553"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGS0715729.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            35666..36049
                     /locus_tag="ACL72M_000554"
     CDS             35666..36049
                     /locus_tag="ACL72M_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715730.1"
                     /translation="MGKENVRMRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVR
                     EYVPKKERIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQ
                     AKRIHRAFCIRLCLRAQFLLSNNDS"
     gene            36457..36756
                     /locus_tag="ACL72M_000555"
     CDS             36457..36756
                     /locus_tag="ACL72M_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715731.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(36851..37288)
                     /locus_tag="ACL72M_000556"
     CDS             complement(36851..37288)
                     /locus_tag="ACL72M_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715732.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(37419..37940)
                     /locus_tag="ACL72M_000557"
     CDS             complement(37419..37940)
                     /locus_tag="ACL72M_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0034258 - nicotinamide riboside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HGS0715733.1"
                     /translation="MLSTRFTGKLSKWENYFGIVNTILSGAIDYILGNKAAIITYPVT
                     FLIYTFAIKKWKASQEGRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLA
                     YVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNA
                     IGALFVWNDEEVR"
     gene            complement(38264..38914)
                     /locus_tag="ACL72M_000558"
     CDS             complement(38264..38914)
                     /locus_tag="ACL72M_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGS0715734.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEILE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            39026..39868
                     /locus_tag="ACL72M_000559"
     CDS             39026..39868
                     /locus_tag="ACL72M_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0715735.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            39944..40381
                     /locus_tag="ACL72M_000560"
     CDS             39944..40381
                     /locus_tag="ACL72M_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGS0715736.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            40449..40751
                     /locus_tag="ACL72M_000561"
     CDS             40449..40751
                     /locus_tag="ACL72M_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715737.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(40842..41915)
                     /locus_tag="ACL72M_000562"
     CDS             complement(40842..41915)
                     /locus_tag="ACL72M_000562"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGS0715738.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            42071..42748
                     /locus_tag="ACL72M_000563"
     CDS             42071..42748
                     /locus_tag="ACL72M_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0715739.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            42741..43715
                     /locus_tag="ACL72M_000564"
     CDS             42741..43715
                     /locus_tag="ACL72M_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGS0715740.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(43764..45707)
                     /gene="thrS"
                     /locus_tag="ACL72M_000565"
     CDS             complement(43764..45707)
                     /gene="thrS"
                     /locus_tag="ACL72M_000565"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGS0715741.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(45765..46088)
                     /locus_tag="ACL72M_000566"
     CDS             complement(45765..46088)
                     /locus_tag="ACL72M_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGS0715742.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(46519..46719)
                     /locus_tag="ACL72M_000567"
     CDS             complement(46519..46719)
                     /locus_tag="ACL72M_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715743.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            46957..47586
                     /locus_tag="ACL72M_000568"
     CDS             46957..47586
                     /locus_tag="ACL72M_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS0715744.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            47727..47996
                     /gene="rpsO"
                     /locus_tag="ACL72M_000569"
     CDS             47727..47996
                     /gene="rpsO"
                     /locus_tag="ACL72M_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGS0715745.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            48811..49425
                     /locus_tag="ACL72M_000570"
     CDS             48811..49425
                     /locus_tag="ACL72M_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGS0715746.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(49717..50466)
                     /locus_tag="ACL72M_000571"
     CDS             complement(49717..50466)
                     /locus_tag="ACL72M_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGS0715747.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            50599..52935
                     /locus_tag="ACL72M_000572"
     CDS             50599..52935
                     /locus_tag="ACL72M_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS0715748.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLMETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDSIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            53037..53714
                     /locus_tag="ACL72M_000573"
     CDS             53037..53714
                     /locus_tag="ACL72M_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGS0715749.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            53701..54498
                     /locus_tag="ACL72M_000574"
     CDS             53701..54498
                     /locus_tag="ACL72M_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGS0715750.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            54515..55618
                     /locus_tag="ACL72M_000575"
     CDS             54515..55618
                     /locus_tag="ACL72M_000575"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS0715751.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDNLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            55688..55816
                     /locus_tag="ACL72M_000576"
     CDS             55688..55816
                     /locus_tag="ACL72M_000576"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715752.1"
                     /translation="MDRTDEVSSKHCFEVVDRTDEVSNHTHGKATLTWFELDFRRV"
     gene            55919..56938
                     /gene="galE"
                     /locus_tag="ACL72M_000577"
     CDS             55919..56938
                     /gene="galE"
                     /locus_tag="ACL72M_000577"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS0715753.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            56940..57893
                     /locus_tag="ACL72M_000578"
     CDS             56940..57893
                     /locus_tag="ACL72M_000578"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0715754.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(57955..58161)
                     /locus_tag="ACL72M_000579"
     CDS             complement(57955..58161)
                     /locus_tag="ACL72M_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGS0715755.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            58213..58689
                     /locus_tag="ACL72M_000580"
     CDS             58213..58689
                     /locus_tag="ACL72M_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGS0715756.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            58698..59369
                     /gene="cmk"
                     /locus_tag="ACL72M_000581"
     CDS             58698..59369
                     /gene="cmk"
                     /locus_tag="ACL72M_000581"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGS0715757.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEDLLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            59500..59838
                     /locus_tag="ACL72M_000582"
     CDS             59500..59838
                     /locus_tag="ACL72M_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGS0715758.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            59841..60470
                     /locus_tag="ACL72M_000583"
     CDS             59841..60470
                     /locus_tag="ACL72M_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGS0715759.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            60710..61861
                     /locus_tag="ACL72M_000584"
     CDS             60710..61861
                     /locus_tag="ACL72M_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0715760.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            62174..62923
                     /gene="truA"
                     /locus_tag="ACL72M_000585"
     CDS             62174..62923
                     /gene="truA"
                     /locus_tag="ACL72M_000585"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGS0715761.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            62913..63686
                     /locus_tag="ACL72M_000586"
     CDS             62913..63686
                     /locus_tag="ACL72M_000586"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS0715762.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            63664..64125
                     /locus_tag="ACL72M_000587"
     CDS             63664..64125
                     /locus_tag="ACL72M_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0715763.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            64352..64708
                     /locus_tag="ACL72M_000588"
                     /pseudo
     CDS             64352..64708
                     /locus_tag="ACL72M_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        19029 a        11943 c        14687 g        19049 t
ORIGIN      
        1 ctagtttggc tcagccaaac taggattttc ttacacgttt ttgtctacga tagccgttga
       61 gttttttatt ttcccagtag ctattaaaga ttttttcctt gctttcgcga ttgatttcca
      121 aaaagtaggc ataaatcaaa tcgataaaga agagcatagg aagttgagcg gatattcgtt
      181 ggatatagga gggttggctg tgggtggcta caagaacagt ctctgtatag gtctggctat
      241 ttttattggg aacacttgta aagagtacag tctttgcccc catctccttg gcatctaata
      301 gactatctaa aatagaagga gttgagcctg aaagtgagaa gcccagtact agacaatttt
      361 catccatgat gctggttgtc caggcaaagc cgtcttggtc tgtcaaagct tcgcagacca
      421 cacctaatcg cataaaacgt aatttcattt cacgggcgac gaggccagaa ctccctgttc
      481 caaagaagta gatacgctca gcatcttcga ttagctgggc aattcgttct agttggattt
      541 cgtcaatcaa gtcttgtgtt tgttccctca tattgctata acttctgagg actcgtttgg
      601 tcagtggact gtgcttggaa acttggttgg cttgattttc tgcctgatgt tggtattgga
      661 aaataaattc tcggtagcca gtaaagccac actttttagc aaagcgggtc aaagcagctt
      721 gagaaatatg taatttttgg gtgacttgtt gagaagataa atcatctgta atcgtttcag
      781 cttgcaaaaa atagcgagcg atttcttgct ctaggtctgt catttcttca aaatgtgaat
      841 caatgatagt tgcgatatct ggtttgtcca tagggaaagc tcctttacat gagtcatact
      901 ggaagactag atcagggaat agtcacactt cattataaca cataatataa ggatagataa
      961 ataaaaacgc atctctgttt taaaaacgaa aaaatcgaaa aagcttctct cttttccata
     1021 attttctact caaattgtgg tacaattaag agtaagattt taagttagaa atgagactga
     1081 tttgtatgag aaaatttaac agccattcga ttccgattcg gcttaattta ttgttttcaa
     1141 tcgtcatttt actctttatg accattattg gtcgtttgtt gtatatgcag gttttgaaca
     1201 aggattttta cgaaaaaaag ctagcctcag ctagtcagac caagattaca agcagttcag
     1261 cccgtgggga aatttatgat gctagtggaa aacctttggt agaaaatacg ttaaagcagg
     1321 ttgtttcctt tacgcgtagc aataaaatga cggctacaga cttaaaagaa acagctaaaa
     1381 agttactgac ttatgtgagc atcagttctc caaatttgac agaacgccag ctggcggatt
     1441 actatttggc tgatcctgaa atctataaaa aaatagtgga agctctccca agcgagaaac
     1501 gcttggattc agatggcaat cgtctatccg aatcagaact gtataacaat gcggtcgata
     1561 gtgtacaaac gagtcaacta aactatacag aggatgaaaa gaaagaaatc tatcttttta
     1621 gtcagttaaa tgctgttgga aactttgcga caggaaccat tgctacagat cctctaaatg
     1681 attctcaggt ggctgttatt gcctctattt caaaggagat gcctggcatt agtatttcta
     1741 cttcttggga tagaaaggtt ttggaaactt ccctttcttc tatagttggg agtgtatcca
     1801 gtgaaaaagc tggtctccca gcggaagaag cagaagccta tcttaaaaaa ggctattctc
     1861 taaatgatcg tgtaggaacc tcctatttgg aaaagcaata tgaagagacc ttacaaggaa
     1921 aacgctcggt aaaagaaatc catctggata aatatggcaa tatggaaagc gtggatacaa
     1981 ttgaggaagg tagtaaggga aacaatatca aactgaccat tgatttggct ttccaagata
     2041 gcgtggatgc tttactgaaa agttatttca attctgagct agaaaatggt ggagccaagt
     2101 attctgaagg tgtctatgca gtcgccctta acccaaaaac aggtgcggtt ttgtctatgt
     2161 cagggattaa acatgacttg aaaacgggag agttgacgcc tgattccttg ggaacggtaa
     2221 ccaatgtctt tgttccaggt tcggttgtca aggcggcgac catcagctca ggttgggaaa
     2281 atggagtctt gtcaggaaac cagaccttga cagaccagtc cattgtcttc caaggttcag
     2341 ctcccatcaa ttcttggtat actcaggctt acggttcatt ccctatcaca gcggtccaag
     2401 ctctggagta ttcatcaaat acctatatgg tccaaacagc cttaggtctt atggggcaaa
     2461 cctatcaacc caatatgttt gtcggcacca gcaatctaga gtctgctatg gagaaactgc
     2521 gttcaacctt tggcgaatat ggcttgggta ctgcgacagg aattgaccta ccagatgaat
     2581 ctactggatt tgttcccaaa gagtatagct ttgctaatta cattactaat gcctttgggc
     2641 agtttgataa ctatacgccg atgcagttgg ctcagtatgt agcaactatt gcaaataatg
     2701 gtgttcgtgt ggctcctcgt attgttgaag gcatttatgg taataatgat aagggaggac
     2761 tgggtgactt gattcagcaa ctgcaaccga cagagatgaa taaggtcaat atatccgact
     2821 ccgatatgag catcttgcac caaggttttt atcaggttgc ccatggtact agtggattga
     2881 caactggacg tgccttttca aatggtgcct tggtatccat tagcggaaaa acaggtacag
     2941 ccgaaagcta tgtggcagat ggtcagcaag caaccaatac caatgcggtg gcctatgccc
     3001 catctgataa tccccaaatc gctgtcgcag tggtctttcc tcataatacc aatctaacaa
     3061 atggtgtagg accttccatt gcgcgtgaca ttatcaatct gtatcaaaaa taccatccaa
     3121 tgaactagaa aggaaattat gctttatcca acacctattg ccaagttgat tgacagttat
     3181 tctaagttac caggtatcgg gattaagacg gctacgcgtc tggcctttta tacgattggg
     3241 atgtctgctg atgatgtcaa tgaatttgca aaaaatctcc tttctgctaa gagagaattg
     3301 acatattgtt ctatttgtgg acgtttgaca gacgacgatc cttgttctat ctgtactgat
     3361 tcgactcgtg accagacaac aattttagtt cttgaggata gtagagatgt ggcagccatg
     3421 gaaaatatcc aagaatacca tggactctat catgtcctgc atggcctcat ttctcctatg
     3481 aatggtatca gtccggacga tatcaatctt aagagcctta tgactcgtct tatggatagt
     3541 gaggtttcag aagtgattgt ggcgactaat gctacagcgg atggtgaagc gacctccatg
     3601 tatctttcac gtttgctcaa gccggctggt atcaaggtta cgcgtctagc acgaggtctc
     3661 gctgtgggag cggacattga gtatgcggac gaagtgacac tcttacgagc gattgaaaat
     3721 cggacagagt tgtaagtgta ggcaaattta cgaactccat tcatttataa aaaatcaaag
     3781 aggctgaaaa tcgttcctat cggcctcttt ttgtatagtg tgatgagtag aatcaggttc
     3841 aagttttaaa aaaccaagca aatatgatat actaaagagc gagtattcta gtagaattag
     3901 gacaaataat atgaaacaaa cgattattct tttatatggt ggacggagtg cggaacgcga
     3961 agtctctgtc ctttcagctg agagtgtcat gcgtgcggtc aattacgacc gtttcacagt
     4021 caagactttc tttatcagtc agtcaggtga ctctatcaaa acgcaggaat ttagtcatgc
     4081 tccggggcaa gaagaccgtc tcatgaccaa tgaaaccatt gattgggata agaaagttgc
     4141 accaagtgct atctacgaag aaggtgcagt ggtctttcca gtccttcacg ggccaatggg
     4201 agaagatggc tctgttcaag gattcttgga agttttgaaa atgccttacg ttggttgcaa
     4261 cattttgtca tcaagtcttg ccatggataa aatcacgact aagcgtgttc tggaatctgc
     4321 tggtattgcc caagttcctt atgtggctat cgttgaaggc gatgatgtga ctgctaaaat
     4381 agctgaagtg gaagaaaaat tggcttatcc agtcttcact aagccgtcaa acatggggtc
     4441 tagtgtcggt atttctaagt ctgaaaacca agaagaactc cgtcaagcct taaaacttgc
     4501 cttccgatat gacagccgtg tcttggttga gcaaggagtg aatgcccgtg aaattgaggt
     4561 tggcctcttg ggtaactacg atgtcaagag cacgctacct ggagaagttg tcaaggacgt
     4621 tgccttttat gactacgatg ccaagtatat tgataacaag gttactatgg atattcctgc
     4681 caaaatcagt gatgatgtgg tggctgtcat gcgtcaaaat gcagaaacag ccttccgtgc
     4741 cattggtggc cttggtctat ctcgttgcga tttcttctat acagataagg gagagatttt
     4801 tctcaacgag ctcaatacca tgccaggttt cacccagtgg tctatgtacc cactactttg
     4861 ggaaaatatg gggatcagct acccagaact aatcgagcgt ttggttgacc ttgccaagga
     4921 aagttttgac aagcgcgaag cgcatttgat ataaaatgaa agagagggta gaagccagaa
     4981 ccatcactgc aaggtgacta gagttctcgg acttcagccc tttttaaagg agtagaaatg
     5041 aaattaacaa tccatgaaat tgcccaagtt gttggagcca aaaatgatat cagtatcttt
     5101 gaggacactc agttagaaaa agctgagttt gatagtcgtt tgattggaac tggagattta
     5161 tttgtgccac ttaaaggtgc gcgtgatggc catgacttta ttgaaacagc ctttgaaaat
     5221 ggtgcagcag taaccttgtc tgagaaagag gtctcaaatc atccttacat tttagtagat
     5281 gatgttttga cagcctttca atccctagca tcctactatc ttgaaaaaac gactgttgat
     5341 gtctttgctg ttacaggttc aaatggcaag acaacgacta aggatatgtt ggcgcattta
     5401 ctgtcaacaa gatacaagac ctacaaaaca caaggcaatt acaataatga gattggcctt
     5461 ccttacacag ttcttcatat gcctgaagga acagaaaagt tggttttgga gatgggacag
     5521 gatcacttgg gagatattca tctcttgtct gaattggctc gtccaaaaac agccatcgtg
     5581 accttggttg gagaagctca tttggccttt ttcaaagatc gttctgagat tgctaaagga
     5641 aaaatgcaaa ttgcagacgg aatggcttca ggttccttgc ttttagcgcc ggctgaccct
     5701 atcgtagagg actatttgcc aattgataaa aaggtggttc gttttggtca aggagcagag
     5761 ctggaaatta ctgacttggt tgagcgtaag gacagtctga cctttaaggc taatttcttg
     5821 gaacaagccc ttgatttgcc agtaactggc aagtacaatg cgacaaatgc tatgattgca
     5881 tcctatgttg ccttgcaaga aggagtttca gaggagcaaa ttcgtttggc attccaacat
     5941 cttgaattga cgcgtaaccg taccgagtgg aagaaagcag ccaatggagc agatatcctg
     6001 tcagatgttt acaatgccaa tccaactgct atgaaactga ttttagagac tttctctgcc
     6061 attccagcca atgaaggtgg caagaaaatt gcagtgttgg cggatatgaa ggagcttggt
     6121 gaccagtctg ttcaacttca taatcagatg attttgagcc tctccccaga tgtgcttgat
     6181 atcgttattt tctatggaga agatattgct cagttggctc aattggccag tcaaatgttt
     6241 ccaatcggcc acgtttacta cttcaagaaa acagaagacc aggatcaatt tgaagaccta
     6301 gtcaagcagg ttaaggaaag ccttggagcc tatgaccaaa tcttgctaaa aggttctaac
     6361 tctatgaatc tagccaaatt ggtagaaagt ttagaaaatg aatgcaagtg attttgctaa
     6421 gtatcttcaa agaatgattg ctcttacaga tactggacta acctttacaa aggatccgtt
     6481 tgaccgtgag cgctacgaag acttgcgaag tctgttatct gaaatgttga atcaggtatc
     6541 agaccttgat gcagacgaag tggcagaact cttgaaaccg acctccgctt atgcgactcc
     6601 tttaatggac gtccgtgctt ggatagttga ggatgaaaaa atttgtctgg ttaggggaca
     6661 aggagagaat gattgggctt tgccaggtgg ctttggcgag gtcggttatt caccaactga
     6721 aaatattctc aaggaaattg aagaagaaac cggttttaaa gccaaagttg aacgactact
     6781 agctgttttt gataccaatc gtttccaact acagagcaaa caatatgcaa agtttgtttt
     6841 tgaatgtaag cttctcgatg gacaatttca agaaaatcaa gaaatcgctg accttcaatt
     6901 ttttgcaatt gaccaactgc cgaatttatc tgaaaaacgc attaccaagg agcaaataga
     6961 gcttctttgg caggtttatc aaggtcatag ggggcaatat cttgactaag aagatgatta
     7021 tcgtatttct aaatccattt ttaacaacta gcatggtata ataatatgca ggaaaatttt
     7081 gaattatgag gaagactaga tgaatttatg ggatattttc tttacgactc aggcaaccga
     7141 gccgcccaaa tttgaccttt tttggtatgt tagcctattt acgctcttag ccttaacctt
     7201 ttatacagcc catcgctatc gtgaaaataa ggtttaccaa cgatttttcc aaatcttgca
     7261 gactgttcag ttaatccttc tttatggttg gtactgggtc aatcatatgc cactgtcaga
     7321 aagcctaccc ttttaccatt gccgtatggc tatgtttgtg gtactcttgc ttcctggtca
     7381 atccaaatat aaacaatact ttgcattatt gggaacattt gggacattag cagcctttgt
     7441 ttatccagtg ccagatgctt acccttttcc acatatcacc attctatcct ttatctttgg
     7501 tcatttagca ctcttgggga actctctagt ttatctattg agacagtata atgcgcgatt
     7561 gctggatgtg aagggaattt ttctcatgac ctttgcccta aatgccttga tttttgtggt
     7621 caatttggtg acaggtggcg attacggatt tttgacaaaa ccgccattgg ttggggatca
     7681 cggtctagta gctaattatt tacttgtttc aattgtgctg gtagctacta tcagtttgac
     7741 taagaaaatc ttagaattct ttttagctca agaagcagaa aaaatgattg caaaggaagc
     7801 ttaacacaga gctttctttt ttgctcttag agagttttta caagcagctt ataaaataag
     7861 aatttctgaa tagacaaact caaaaaatgg ctgggaaatt taggaaaaaa gcaagcacga
     7921 ttaaattttt tgtgttataa tattttgtga atagctatgc ctatgtttag ctatggaata
     7981 atacgaagtg cgaaacttgg aagatagaga ggaagcgatg taatggctag agaaggcttt
     8041 tttacaggtc tagatattgg aacaagctct gtcaaggtgc ttgtggccga gcagagaaat
     8101 ggtgaattaa atgtaattgg cgtgagtaat gccaaaagta aaggtgtaaa ggatggaatt
     8161 attgttgata ttgatgcagc agcaactgct atcaagtcag ccatttccca agcggaagaa
     8221 aaggcaggca tttcgattaa atcagtgaat gtcggcttgc ctggtaatct tttgcaggta
     8281 gaaccaactc aggggatgat tccagtaaca tctgatacta aggaaattac ggatcaagat
     8341 gttgaaaatg ttgtcaaatc agctttgaca aagagtatga cacctgaccg tgaagtcatt
     8401 acctttattc ctgaagaatt tattgtggat ggtttccaag ggattcgtga cccacgtggc
     8461 atgatggggg ttcgccttga aatgcgtggt ttgctttata caggacctcg tactatcttg
     8521 cacaatttgc gtaagacggt tgagcgtgca ggtgttcagg ttgaaaatgt tatcatttca
     8581 ccactagcaa tggttcagtc tgttttgaac gaaggggaac gtgaatttgg tgctacagtg
     8641 attgatatgg gggcaggtca aacgactgtc gctacaatcc gtaatcaaga actccagttc
     8701 acacatattc tccaagaagg tggagattat gtaactaaag atatctccaa ggttttgaaa
     8761 acctctcgca aattagcgga aggcttaaaa ctgaattacg gggaagccta tccgcctctt
     8821 gcaagcaaag aaaccttcca agtagaggtt attggagaag tagaagcagt cgaagtgacg
     8881 gaagcctact tgtcagaaat tatttctgca cgaatcaagc acatccttga acaaatcaag
     8941 caagaattag atagaaggcg tctattggac ctccctggtg gtattgtctt aatcggtggg
     9001 aatgccattt taccaggtat ggttgagctt gctcaggaag tctttggcgt ccgtgtcaag
     9061 ctttatgttc caaatcaagt tggtatccgt aatccagcct ttgcgcatgt gattagttta
     9121 tcagaatttg cgggtcaatt aacagaagtt aatcttttgg ctcagggagc gataaaaggt
     9181 gagaatgact taagtcatca gccaattagt tttggtggga tgctgcaaaa aacagctcag
     9241 tttgtacaat caacgcctgt tcaaccagct cctgctccag aagtagagcc ggtggcgcct
     9301 acagaaccaa tggcggattt ccaacaagct tcacaaaata aaccgaaatt agcagatcgt
     9361 ttccgtggct tgatcggaag catgtttgac gaataaagag gaaaaataaa ttatgacatt
     9421 ttcatttgat acagctgctg ctcaaggggc agtgattaaa gtaattggtg tcggtggagg
     9481 tggtggcaat gccatcaacc gtatggtcga cgaaggtgtt acaggcgtag aatttatcgc
     9541 agcaaacaca gatgtacaag cattgagtag tacaaaagct gagactgtta ttcagttggg
     9601 acctaaattg actcgtggtt tgggtgcagg aggtcaacct gaggttggtc gtaaagccgc
     9661 tgaagaaagc gaagaaacac tgacggaagc tattagtggt gccgatatgg tcttcatcac
     9721 tgctggtatg ggaggaggct ctggaactgg agctgctcct gttattgctc gtatcgccaa
     9781 agatttaggt gcgcttacag ttggtgttgt aacacgtccc tttggttttg aaggaagtaa
     9841 gcgtggacaa tttgctgtag aaggaatcaa tcaacttcgt gagcatgtag acactctatt
     9901 gattatctca aacaacaatt tgcttgaaat tgttgataag aaaacaccgc ttttggaggc
     9961 tcttagcgaa gcggataacg ttcttcgtca aggtgttcaa gggattaccg atttgattac
    10021 caatccagga ttgattaacc ttgactttgc cgatgtgaaa acggtaatgg caaacaaagg
    10081 gaatgctctt atgggtattg gtatcggtag tggagaagaa cgtgtggtag aagcggcacg
    10141 taaggcaatc tattcaccac ttcttgaaac aactattgac ggtgctgagg atgttatcgt
    10201 caacgttact ggtggtcttg acttaacctt gattgaggca gaagaggctt cacaaattgt
    10261 gaaccaggca gcaggtcaag gagtgaacat ctggctcggt acttcaattg atgaaagtat
    10321 gcgtgatgaa attcgtgtaa cagttgtcgc aacgggtgtt cgtcaagacc gcgtagaaaa
    10381 ggttgtggct ccacaagcta gatctgctac taactaccgt gagacagtga aaccagctca
    10441 ttcacatggc tttgatcgtc attttgatat ggcagaaaca gttgaattgc caaaacaaaa
    10501 tccacgtcgt ttggaaccaa ctcaggcatc tgcttttggt gattgggatc ttcgccgtga
    10561 atcgattgtt cgtacaacag attcagtcgt ttctccagtc gagcgctttg aagccccaat
    10621 ttcacaagat gaagatgaat tggatacacc tccatttttc aaaaatcgtt aagtaaatga
    10681 atgtaaaaga aaatacagaa cttgtttttc gagaagttgc agaggctagt ctgagtgctc
    10741 atcgagagag tggttcggtc tctgtcattg cagttaccaa gtatgtagat gtaccgacag
    10801 cggaagcctt gcttccgcta ggtgttcatc atatcggtga aaatcgtgta gataagtttc
    10861 tggaaaaata tgaagcttta aaagatcgag atgtgacttg gcatttgatt ggtaccttgc
    10921 aaagacgtaa ggtgaaagat gtcattcaat acgttgatta tttccatgca ttggactcag
    10981 taaagctagc aggggaaatt caaaaaagaa gtgaccgagt catcaagtgt ttccttcaag
    11041 taaatatttc taaagaagaa agcaaacacg gtttttcgag agaggaactg ctggaaatct
    11101 tgccagagtt agccagacta gataagattg aatatgttgg tttaatgacg atggcacctt
    11161 ttgaggctag cagtgagcag ttgaaagaga ttttcaaggc ggcccaagat ttacaaagag
    11221 aaattcaaga gaaacaaatt ccaaatatgc ctatgaccga gttaagtatg ggaatgagtc
    11281 gtgattataa agaagcgatt caattcggtt ccacttttgt tcgtataggt acatcatttt
    11341 ttaagtagga gagaaccatg tctttaaaag atagattcga tagatttata gattatttta
    11401 cggaggatga ggattcaagt ctcccttatg aaaaaagaga tgagcctgtg tttactccag
    11461 taaattcttc acaggaaccg gctctcccaa tgaatcaacc ttcacagtcg gctggtacaa
    11521 aagagaacaa tatcaccaga cttcatgcaa gacaacagga attggcaaat cagagtcagc
    11581 gtgcaacgga taaggtcatt atagatgttc gttatcctag aaaatatgag gatgcaacag
    11641 aaattgttga tttattggca ggaaacgaaa gtatcttgat tgattttcag tatatgacag
    11701 aggtgcaggc tcgtcgttgt ttggactatt tggatggagc ttgtcatgtt ttagctggaa
    11761 atttgaaaaa ggtagcttct accatgtatt tgttgacacc agttaatgtt attgtaaatg
    11821 ttgaagatat ccgtttacca gatgaagatc aacagggtga gttcggtttt gatatgaagc
    11881 gaaatagagt acgataatga tttttttaat tcgtatgatt tataatgcag tggatattta
    11941 ctccctgatt ttggtagcct tcgctgtcat gtcttggttt ccaggtgcct acgaatccag
    12001 tttaggtcgt tggattgtag cgttggtgaa accagtactt gctcccttgc aacgcctgcc
    12061 tttacagata gcgggtcttg atttatctgt ttgggtcgcg attgttttgg ttcgattttt
    12121 aggagaaaac ctagtgcgtt ttctggcgat gataggatga ataaagggat ttatcagcat
    12181 ttctccatag aagatcgtcc atttcttgac aagggaatgg aatggataaa gaaggtagaa
    12241 gatagctatg ctcctttttt aactcctttt atcaatcctc atcaggagaa gctattaaag
    12301 attttggcca aaacctatgg tcttgcttgt agcagtagtg gggaattcgt ctcgagtgag
    12361 tatgttcgag ttttattata cccagattat ttccaaccag agttttcaga ttttgaaata
    12421 tctctccaag aaattgtgta ttccaataaa tttgaacatt taacgcatgc taagatttta
    12481 gggacagtca tcaatcaatt agggattgaa cggaaacttt ttggagatat cctagtagat
    12541 gaagaacggg cgcagattat gattaatcag cagtttcttc ttctctttca agatggacta
    12601 aagaaaattg gtcgtatacc tgtttcgctg gaggaacgtc ctttcaccga gaaaatagat
    12661 aagctagaac agtatcgaga actggattta tctgtgtcta gttttcgatt agatgttctt
    12721 ttatcaaatg ttttgaaact atctaggaat caagcaaacc agttgattga aaagaaactt
    12781 gtccaagtaa attatcatgt ggtagacaaa tcagattaca ctgttcaagt tggagacttg
    12841 attagtgtga gaaaatttgg tcgcttgaga ttacttcaag ataagggaca aacgaaaaaa
    12901 gagaagaaaa aaataaccgt ccagttatta ttaagtaagt gaggaataga atgccaatta
    12961 catcattaga aataaaggac aagacttttg gaactcgatt cagaggtttt gatccagaag
    13021 aagtcgatga atttttagat attgtggttc gtgattacga agatcttgtg cgtgcgaatc
    13081 atgataaaaa tttgcgtatt aagagtttag aagagcgttt gtcttacttt gatgaaataa
    13141 aagattcatt gagccagtct gtattgattg ctcaggatac agctgagaga gtgaaacagg
    13201 cggcgcatga acgttcaaac aatatcattc atcaagcaga gcaagatgcg caacgcttgt
    13261 tggaagaagc taaatataag gcaaacgaga ttcttcgtca agcaactgat aatgctaaga
    13321 aagtcgctgt tgaaacagaa gaattgaaga acaagagccg tgtcttccac caacgtctca
    13381 aatctacaat tgagagtcag ttggctattg ttgaatcttc agattgggaa gatattctcc
    13441 gtccaacagc tacttatctt caaactagtg atgaagcctt taaagaagtg gttagcgaag
    13501 tacttggaga accgattcca gctccaattg aagaagaacc aattgatatg acacgtcagt
    13561 tctctcaagc agaaatggaa gaattacaag ctcgtattga ggtagccgat aaagaattgt
    13621 ctgaatttga agctcagatt aaacaggaag tggaaactcc aactcctgta gtgagtcctc
    13681 aagttgaaga agagcctctg ctcatccagt tggcccaatg tatgaagaac cagaagtagc
    13741 tccagtgcat ccgacaggtc caacaccagc tacagaaact gttgattcag caccaggatt
    13801 tgaagcaccg caagaatccg ttacaatttt ataagaaacg atgtgagaac aatatcttat
    13861 ccttatattt ccagcgagca ggagatggtg tgagtcctgc attccctaac gataagatta
    13921 tcctctcaaa aactcaagtc tgaagctagt aagatttgac gtttcccacg ttacgggata
    13981 agagggagaa agactaaatc tttttccgaa taaaggtggt accacgattt tcgtcctttt
    14041 tggaagtcgt ggtttttaat ttgttattat ttataaagga gataccatga aactcaaaga
    14101 tacccttaat cttgggaaaa cagctttccc aatgcgtgca ggccttccga ccaaagagcc
    14161 agtttggcaa aaggaatggg aagatgcaaa actttaccaa cgtcgtcaag aactaaatga
    14221 agggaaaccg cattttgtct tgcatgatgg ccctccatac gcaaacggaa atatccacgt
    14281 tggacatgcc atgaatcata tctcaaaaga tatcatcatt cgttctaagt ctatgtcagg
    14341 ttttaacgca ccttatatcc caggttggga tactcatggt ctgccaatcg agcaagtttt
    14401 ggcaaagcaa ggtgtgaagc gcaaagaaat ggacttggtt gagtacttga aactctgtcg
    14461 tgagtacgct ctttctcaag tttataaaca acgtgatgat ttcaaacgct tggggatgtc
    14521 aggtgactgg gaaaatttat atgtgacttt aactccagac tatgaagcag cccaaatccg
    14581 tgtctttggt gagatggcta ataagggtta tatctaccgt ggtgccaagc cagtttactg
    14641 gtcatggtca tctgagtcag cccttgccga agcggaaatt gaataccatg atttggtttc
    14701 gacttcactt tattatgcca ataaggtaaa agatggcaaa ggtatcctag atacagatac
    14761 ttatatcgta gtctggacaa caactccatt taccatcaca gcttctcgtg gtttgactgt
    14821 tggtgcagat attgattacg ttttggttca acctgctagt gaaactcgta agtttgtcgt
    14881 tgctgcagaa ttgttgacta gcttgtctga gaaatttggc tgggctgatg ttcaagtgtt
    14941 ggcaacttac cgtggtcaag aactcaacca catcgtaaca gaacacccat gggatacagc
    15001 tgtagatgag ttggtaatcc ttggtgatca cgttaccact gactctggta caggtatcgt
    15061 ccatacagcc cctggttttg gtgaggacga ctacaatgtt ggtattgcta atggtcttga
    15121 agtcgcagtg actgttgacg aacgcggtat catgatggcg aatgctggtc ctgagtttga
    15181 aggtcagttc tacgacaagg ttgtaccaac tgttattgaa aaacttggta acctccttct
    15241 agcccaagaa gaaatctctc actcataccc atttgactgg cgtactaaga aaccaatcat
    15301 ctggcgtgca gttccacaat ggtttgcctc agtttcaaaa ttccgccaag aaatcttgga
    15361 tgctattgat aaagttaaat tccatacaga atggggtaaa gtacgtctat ataatatgat
    15421 tcgtgaccgt ggtgactggg ttatctctcg tcaacgtgct tggggtgttc cacttccaat
    15481 cttctatgca gaagacggta cagctatcat gacagctgag actattgaac atgtggcgca
    15541 actctttgaa gtacatggtt caagcatttg gtgggaacgt gatgccaaag acctcttacc
    15601 agaaggattt acacatccag gttctccaaa tggggagttc aagaaagaaa cagatattat
    15661 ggatgtatgg tttgactcag gttcatcatg gaatggtgtt ttggtaaatc gtccaaatct
    15721 gacttatcca gctgaccttt accttgaagg ttctgaccaa taccgtggtt ggttcaactc
    15781 atcactcatt acatctgttg ccaaccatgg cgtagcacct tacaaacaaa tcttgtcaca
    15841 aggttttacc cttgatggta aaggtgagaa gatgtctaaa tcacttggaa ataccattgc
    15901 tccaagtgat gttgaaaaac aatttggtgc agaaatcttg cgtctctggg taacaagtgt
    15961 tgactcaagc aatgacgtgc gtatctctat ggatattttg agccaagttt ctgaaactta
    16021 ccgtaagatt cgtaacactc ttcgtttctt gattgccaat acatctgact ttaacccagc
    16081 tcaagatgta gtcgcttacg atgaacttcg ttcagttgat aagtacatga ctattcgctt
    16141 taaccagctt gtcaagacca ttcgtgatgc ctatgcggac tttgaattct tgacaatcta
    16201 caaggccttg gtgaacttta tcaacgttga cttgtcagcc ttctaccttg attttgccaa
    16261 agatgttgtt tacattgaag gtgccaaatc attggaacgc cgtcaaatgc agactgtttt
    16321 ctatgacatt cttgtcaaaa tcaccaaact cttgacacca atccttcctc acactgcgga
    16381 agaaatctgg tcatatcttg agtttgaagc tgaagacttc gttcaattgt cagaattgcc
    16441 agaagctcaa acttttgcta atcaagaaga agtcttggat acatgggcag ccttcatgga
    16501 cttccgtgga caagctcaaa aagccttgga agaagctcgt aatgcaaaag ttatcgggaa
    16561 atcgcttgaa gcacacttga cagtttatcc aaatgaagtt gtgaaaactc tactcgaagc
    16621 agtaaacagc aatgtggctc aacttttgat cgtgtcagac ttgaccatcg cagaagggcc
    16681 agctccagaa gctgccctta gcttcgaaga tgtagccttc acagttgaac gcgctgcagg
    16741 tcaagtatgt gaccgttgcc gtcgtatcga cccaacaaca gcagaacgca gctaccaggc
    16801 agtcatctgt gaccactgtg caagcatcgt agaagaaaac tttgcggaag cagtcgcaga
    16861 aggatttgaa gagaaataag gttgaaaagt ctaggcaaaa ttcaatttga gaagaaaaga
    16921 caactaattt tatagtctat taaacgcatt gtatcacgtt tttgaatacc tgatatgatg
    16981 cgttttttat ttattttaaa aatttgcgag gtatgacttt ttatactcaa caagaatcaa
    17041 agagaaactt agcaagctaa cagtagtaag ataaaatagg aatttgatat tagggataag
    17101 attgctaaat agtgtaatat ttttacaata ataaatttat atagttattt ttggtttctg
    17161 aaaagtatta tattttattt catattatac aaatttttat tttataatat cagaaaatac
    17221 tttttttaaa agcaaatatg atacaatttt atttgaaaaa aataaaaaag gagattttat
    17281 tatgaaatta aaaacacttg ctttaattag tggtatcgtc ggtcttgtgg gaggaatttt
    17341 acttcttatt ggtccttttg tcttgttggg aacagcggta aacacagttg ctacaactct
    17401 taatggagga gctactgcag gggctttttc aggtgttgcc ttactcttga atgccttgaa
    17461 gattgcaaat cttgttcttg gtatcattgc tattgtttac tataaaggag ataatcgtgt
    17521 aggtgcagct ccgtctgtac taatgattgt ttttggtgga gttagtctca ttccattctt
    17581 aggatgggtt ggggggattc ttgttattat cggaggatct ctattccttg caacattgaa
    17641 gaaattcaaa tcagaagaat aaaaggtatt ttagcatgaa aagaacaaaa aagtttatcg
    17701 gtataggagt agctctatta tctctttttc ttctagttgc atgtggaaca taaagttcaa
    17761 aggatacttc aacaagtaat gatgagaaga cagtagcaac atccaatagt tcaaaagaaa
    17821 caatcacttt cgatacaccg gttgtaacag acgatgtgat tgaatcaata cgcacttatg
    17881 cagattatat agatctttat aaaaatattt ttgatgatta ttttactaaa gctgaggaag
    17941 gtttcaaagg cacagctatg gaaaataatg actcgtttac taaactaaaa gagtcaactc
    18001 aaaaattatt cgatgcgcag aaaaaaaggt taaataatga agatagaata gaaacaacta
    18061 aaaacaatgt gattgccaaa cattgtcaaa cagtcctttc ctttttggtt ttgactagct
    18121 tttttgtgaa aaattgtgta aaatagaata gataaacgag gggaaacctc ggaaaattta
    18181 aaggagaatc catctaatgg taaaattggt ttttgctcgc cacggtgagt ctgaatggaa
    18241 caaagctaac cttttcactg gttgggctga tgttgatttg tctgaaaaag gtacacaaca
    18301 agcgattgac gctggtaaat tgatcaaaga agctggtatc aaatttgacc aagcttacac
    18361 ttcagtattg aaacgtgcta tcaaaacaac taacttggct cttgaagctt ctgaccaatt
    18421 gtgggttcca gttgaaaaat catggcgctt gaacgaacgt cactacggtg gtttgactgg
    18481 taaaaataaa gctgaagctg ctgaacaatt tggtgatgag caagttcaca tctggcgtcg
    18541 ttcatacgat gtattgcctc caaatatgga ccgtgatgat gagcactcag ctcacacaga
    18601 ccgtcgttat gcttcacttg acgactcagt aatcccagat gctgaaaact tgaaagtgac
    18661 tttggaacgt gctcttccat tctgggaaga taaaatcgct ccagctctta aagatggtaa
    18721 aaacgtattc gtaggagctc acggtaactc aatccgtgcc cttgtaaaac acatcaaagg
    18781 tttgtcagat gacgagatca tggacgtgga aatccctaac ttcccaccat tggtattcga
    18841 attcgacgaa aaattgaacg tcgtttctga atactacctt ggaaaataaa aaattgtaag
    18901 tctagaattg atttctaggc tttttatgtt agtatggaag tatgataagg aataaaaaac
    18961 aagattatgt actggcctac aagcaaccag tttcaaccac ttacatgggt tgggaagaag
    19021 aagctttacc gataggcaat ggttctttag gagcaaaagt atttggcctt ataggggctg
    19081 aacggattca atttaatgaa aaaagtctct ggtctggagg tccacttcct gatagttcag
    19141 attatcaggg tggaaatctt caggatcagt atgttttttt agctgagatt cggcaggctt
    19201 tggagaagag agattacaat ctggctaagg aactggctga gcagcaccta attgggccaa
    19261 aaacgagtca atatgggacc tatctgtctt ttggggatat tcacattgag ttcagccagc
    19321 aaggtacgac tttgtctcag gtgacggact atcagagaca gctgaatatt agtaaggcac
    19381 ttgtgacgac ttcttatgtc tataagggaa cgcgatttga acgtgaagct tttgcgagtt
    19441 ttccagatga tctcttggtt cagcgtttta ctaaggaagg ggcggaaact ctagatttta
    19501 ctatagaact atccttgacc tgtgatttgg cttctgatgg aaagtatgag caggaaaaat
    19561 ctgattacaa ggagtgtaag ttggatatta ctgattctca tatcttgatg aagggaagag
    19621 ttaaggataa tgatctgcgg tttgctagtt atctagcttg ggaaacggat ggagatatta
    19681 gagtttggtc agatagggtt cagatatcag gagccagtta tgccaatctc ttcttggccg
    19741 ctaagacgga ttttgcccaa aatcctgcta gcaattatcg caagaaacta gatttagagc
    19801 aacaggtgat agacttggtg gacacagcta aagaaaaggg ctatacccaa ttgaaatcaa
    19861 ggcatatcga ggactaccaa gccttattcc agcgtgttca attggatttg gaagctaatg
    19921 ttgacgcatt cactacagat gatttgttaa aaaattataa gccacaagaa gggcaggctt
    19981 tggaggagct gttcttccag tatggacggt atttattgat tagttcgtcc agagactgcc
    20041 cagatgctct accagctaac ctacagggag tctggaatgc ggtcgacaat cctccttgga
    20101 attcggacta tcacttaaat gtcaatctgc agatgaatta ttggccagcc tatgttacca
    20161 atctcctaga gacggtcttt ccagtcatca actatgtaga tgatttgcgt gtctatggtc
    20221 gtctagcggc tgtaaagtat gcaggaatcg tctctcagaa aggtgaggag aatggttggt
    20281 tggttcatac tcaagcgact ccctttggtt ggacggcacc tggttgggat tactattggg
    20341 gttggtcacc agctgccaat gcgtggatga tgcaaaccgt ttatgaagcc tattcatttt
    20401 atagggacca agactatctc agggagaaaa tttatcccat gttgagggaa acggttcgtt
    20461 tttggaatgc ctttttacat aaggatcagc aggcgcagcg ttgggtgtct tctccgtctt
    20521 attccccaga acatgggccg atttcgattg gcaatactta tgaccaatct ctgatttggc
    20581 agttatttca tgattttatt caggctgctc aggaattggg actggatgag gacttgttga
    20641 ctgaggttaa ggagaagtct gatttactaa atcctttgca aatcactcaa tctggtcgaa
    20701 tcagggagtg gtatgaggag gaagagcagt attttcaaaa tgagaaagtg gaggcccagc
    20761 atcggcacgc ttcccatcta gtgggactct atcctggcaa tctctttagc tacaagggac
    20821 aagagtatat tgaagcggta cgtgctagcc tcaatgatcg tggagatggc ggcacaggct
    20881 ggtccaaggc taataagatc aatctctggg cgcgtttggg agatggcaat cgagcccata
    20941 aattattggc agagcagtta aagacatcca ccttgccaaa tctttggtgt agccatcctc
    21001 cttttcagat agatggtaat tttggtgcta ctagtggcat ggcagaaatg ttactccagt
    21061 ctcatgcagc ttatctggta cctctagctg ccctacctga tgcttggtca acaggttctg
    21121 tttcaggctt aatggcacgt ggacattttg aagtgagcat gagctgggaa gataaaaaac
    21181 tcttacagtt gaccatttta tcaaggagtg gaggagattt gcgagtttct tatccagata
    21241 ttgagaagag tgtgattaaa atgaatcaag aaaaaataaa agcgaaatgc atggggaaag
    21301 attgtatttc ggtggcaaca gcagaaggtg atcttgttca attttatttt taagaagatg
    21361 ttataaggca gtaatttgaa actgcctttt aataaggatt taagaatata agcagttttc
    21421 aactagttga aaaaacgtta taatgataat aggaagtaat actcaatgaa aatcaaagag
    21481 cacaaactag gaagctagcc gcaggttgct caaaacagtg ttttgaggtt gcagatggaa
    21541 gctgacgtgg tttgaagaga gattttcgag gagtataatt tgtttgatag agggtgggtc
    21601 tgatggctta tattgagatg aaacactgtt acaagcgtta tcaggttggg gacacggaga
    21661 ttgtggccaa ttgtgatgtg aattttgaga ttgaaaaggg ggagctggtt attatccttg
    21721 gtgcttcagg tgcaggcaag tcaacagttc ttaaccttct tgggggaatg gataccaatg
    21781 atgaagggga aatctggatt gatggtgtta atattgcgga ttatagttcc caccagcgca
    21841 ccaattaccg tagaaatgat gtggggtttg tttttcagtt ttataatcta gtttctaatc
    21901 tgacagctaa ggaaaatgtg gaactggctt ctgaaattgt gacagatgcc ttgaatcctg
    21961 atcaggtctt gacagatgta ggtctggctc atcgtctcaa taactttcca gcccagcttt
    22021 ctggagggga gcaacagcga gtctccattg cacgcgcggt agccaaaaat cctaaaattc
    22081 tcctttgtga tgaaccgact ggagccttgg attatcagac gggcaagcag gttttgaaaa
    22141 ttctccaaga catgtctcgt caaaagggag cgacggtgat catcgtgact cataatggag
    22201 ctttggcgcc cattgctgat cgcgtgattc aaatgcacga tgccagtgtc aaggatgtgg
    22261 tgctcaacca gcatcctcag gatattgaca gtttggagta ctagcatgat caagcgaaaa
    22321 acttattgga aggacttaat tcagtccttc acaggctcca aggggcgttt tttatccatc
    22381 ttgatcctga tgatgttggg atctctagcc ttagtaggcc tcaaagtaac cagtcccaac
    22441 atggaggcga cagctaatgc ttatttaaca actgctcaaa ccttggattt ggcagtcatg
    22501 tctaactatg gcttggatca agcagaccaa gaagaactaa aacagacgga gggcgcagag
    22561 gtcgagtttg gctatttgac agatgtgact atggataatg ggcaggatgc cattcggctg
    22621 tactccaaac cagagcgaat ttcaaccttt cagctaagaa agggacgact tcctcagtca
    22681 gacaaggaaa tcgctttggc cactcatttg caaggccaat acagcgtggg acaggagatt
    22741 agttttaaag aaaaagaaga gggtcattcc tctttaaaag accatactta taccattact
    22801 ggttttgtgg attcggctga aatcctctcc cagcgagata tgggctacgc aggaagtgga
    22861 agtgggactc tgacagccta tggggtgatt ttacctagtc agtttgatca gaaagtctac
    22921 aatatagctc gtttgaaata tcaagattta gcaggtttaa atgccttttc atcagcttat
    22981 gaagaaaaat ccaagcaaca tcaggaagac cttgaacaaa ctttatcaga taatggcaag
    23041 gtacgtctgc aacttttgaa aaaagaagga caagagtctc tagacaaggg gcaagagacc
    23101 cttgacaagg ctcagactaa tttgcaggaa ggcaagcgtc gtttagcagc tgctcaagct
    23161 cgtatacagg ctcaagaaag tcaactagcc ttgtttcctc aagttcagag agagcaggct
    23221 agtgctcaac ttacccaagc caagcaggaa ttgggcaagg aagaggacaa actaaagcaa
    23281 gctgaacaaa atctagccca agaaaaggaa aaattagaaa aacatcagca agtcttggac
    23341 gatttggcgg agccaaggta tcaggtctat aatcgtcaga ccatgccagg tggtcagggc
    23401 tatcttatgt atagcaatgc ttcatccagt attcgagcag tgggcaatat ctttcctgtg
    23461 gtactttatg ccgtagcatc catggtgacc tttacgacca tgactcgctt tgtagacgaa
    23521 gagcgaactc atgcagggat ttttaaggcc ttgggttacc gtagtaagga tattatcacc
    23581 aagtttctcc tttatggact agtagctggg actgtcggaa cggctctagg tagtatactt
    23641 ggtcattatt tgctagccag tgtaatttca agtgtcatta caaaaggcat agtggtggga
    23701 gaaacccaga ttcagttcta ttggacctat agcttactag ctcttgtctt gagttggttg
    23761 gcgagtgtgt taccagtcta tctggtggct tggagggaac ttcatgccga agcagcccag
    23821 cttctacttc ctaaacctcc tgtcaaagga gctaaaatct tattggagcg tatcggtttt
    23881 atctggcgtc gtctcagttt tactcataag gtaacagccc gcaacatctt tcgttataag
    23941 cagagaatgt tgatgacaat ctttggtgtg gcaggttctg tagctctgct ctttgcaggt
    24001 ttgggaatcc aatcttctgt agcaggagtt ccgtctaaac agtttcaaca aatccaacag
    24061 tatcagatgc ttgtctctga aactcctagt gcgaccaatc aggacaaggt agagctagca
    24121 gaagtgttga aagggcagga gatactagcc taccagaaaa tctattctaa aacgctagac
    24181 aaggatttca aaggcaaggc tggtcttcaa aacattactc ttatgatgat agagaaggaa
    24241 gatttgactc cctttatcca tcttcaacat catcagcagg agctgacatt aaaagatggc
    24301 atcgttatta cagctaaact cgcccagctg gcaggtgtca aggttgggca gactttagaa
    24361 attgaaggta aggaactaaa ggtcgctgct attactgaga actacgttgg tcactttatt
    24421 tatatgagtc aggctagcta tgagcaactt tacggacagc taccccaagc caacacttat
    24481 ctggtctcat taagggatac cagtgcaact agtatcgaaa gtcaggcggg cttgcttatg
    24541 aatcaatctg cggtgtccag cgttgtccaa aatgcttcag ccattcgact cttcgactct
    24601 atcgctagct cactcaatca gaccatgacc atcttggtca tcgtatcggt tctattagct
    24661 attgtcatcc tttacaatct gaccaatatc aacgtagctg agagaatccg tgaactctcc
    24721 actatcaagg ttctcggttt tcataataat gaagtcaccc tctacattta ccgtgagacg
    24781 attgtgctgt cccttgtggg aatcgtactt ggtctggtag ctggtttcta tttacaccaa
    24841 tttttgattc aaatgatttc gcctgcgact attctctttt atccgcaggt aggctgggaa
    24901 gtctatgtaa tcccagtggc agcagtaagc atcattttga ccttgcttgg tttcttcgtc
    24961 aattattatc tgagaaaggt tgatatgtta gaagccctga aatctgtaga gtaaggtagt
    25021 tatttttagc tgattgaact tctatttatt aatattcaaa aatcctccgt ttcaaagagc
    25081 agggaactct ttgtgacaga ggattttttc tatagggctt tagcagctgc aattgcggct
    25141 tcgaagtttg gctcagaatt gatattatcc acgtattcaa cgtagcgaat cgtattgtca
    25201 gtatcgagga caaagactgc gcgtgctaat aggtgccatt cgttgatcaa gagggcataa
    25261 tcgcgcccga aagaatggtc aaagtagtct gaaagcataa tggcattgtc aaggccttca
    25321 gcaccgcacc aacgtttttg agcaaaaggt aggtccattg aaacagtcaa tacgaccgtg
    25381 ttgtccagtc cagctaattc ttcattaaaa cgacgtgttt gagttgagca gatgcctgta
    25441 tcgatagaag gaacgacact caggactttt ttcttgccat caaaatcagc cagagatttt
    25501 ttagaaagat ctgttgtagt aagagaaaaa tcaagcgcct tgtcgccgcc ttgtagttgt
    25561 ttacctgtaa agctcacagg atttccgaga aaagttacca taggatactc caatcttttt
    25621 tcttccattg tatctgaaac agtcagaatt ttccaatgat ttgaccggaa atgtgggcat
    25681 agaaaaaacg ccagctcaca tgagaatgac gtttttcaga ggcttatttt gccaatcctt
    25741 cagcaatctt gtcaaggttg tatttcatca tgctgtagta gctgtcgcct tctttacctt
    25801 gttctgcgat agagtcagta aagatttgtg cgtagattgg gatgtttgtg tcttgagaaa
    25861 cagttttcat tggacggtca tccacacttg attctacaaa gagtgatgga acttttgttt
    25921 ggcgaagttt ttcaaccaag gtcttgattt gttcaggagt tccttcttct tcagtattga
    25981 tttcccagat gtaggcactt gggacaccat aggctttaga gaagtatttg aatgctcctt
    26041 cgctggttac aatgagtttc ttttcagcag ggatcttatt aaatttatcc ttactttctt
    26101 tatcaagttt gtctaactta tcagtatatt ctttgagatt tttttcatag aattctttat
    26161 tgttagggtc tttggcgctc aattgtttgg cgatattttt agcaaaaata ataccgtttt
    26221 caaggttaag ccaagcgtgt gggtcttctt ttcctttttc attttgacct tcaaggtaga
    26281 taacatcaac gccgtcgctg actgcgaagt agtctttgtt ttcagttttc ttggcatttt
    26341 ctaccaattt tgtaaaccaa gcattgccac ctgtttcaag gttgataccg ttatagaaaa
    26401 tcaaatcagc ctcagaagtt ttcttaacgt cttcaggaag tggttcgtat tcgtgtgggt
    26461 cttgcccaat cggaacgata ctatgaaggt caattttgtc accagcaata tttttagtaa
    26521 tatcagcgat gattgagttt gtagcaacaa cttttagttt ttgaccagaa gttgtatctt
    26581 tttttccgct agcacatgct acaagaatga ttgcagaaag aaagagaacg agtaatgtac
    26641 ctaatttttt cattagatcc tccaatttat tagggctttg ccccttattt taacaaatgt
    26701 ttatttttca gtttcaaata tcgttgtttg ggagcgataa agaagctaat gagaaagaaa
    26761 ctagcagctg taagcacgat actagaacct gccgcaacat taaaactata gccaataaag
    26821 agtcccaaaa ctgaagcagt agctccgaag gttgaggaaa ggaaaatcat gcttttcaga
    26881 ctattagcat acagataagc agttgcagct ggggtaatca gcatggctac aatcaggata
    26941 gttccgacac tttgcatggc tgtcacagac acgagagtca ggagtaccat gagaaggtag
    27001 tgatagaaat tgacaggcat tcccatggct ttagccaaga gttcatcaaa ggaagttatc
    27061 aagagttgct tgaagaaaat ccagattaac aagaggatgg ctgcccccac acccatagta
    27121 ataaacatat ccgtatcttg gacggccagg atattaccaa aaaggatatg gaaaaggtca
    27181 gttgaacttt tagcgacacc aatcaagatg ataccgaggg ctaagaaaga agaaaaggta
    27241 atgccgatgg cggtatcgct tttgataatc gagtttcctt tgatgtaggt aatgatgatg
    27301 gcagctagca atccaaagac aatggctccg ataaagaagt caaggcccaa gatgaaggag
    27361 agggctacac ctggtaagac agcatgtgaa atggcatctc ccatgagtga catcccgcgt
    27421 agaataatga aacatcccac agctccagct acaatcccga cgacaatagc tgttatcaag
    27481 gcattttgta ggaaatggaa tttttgcaat ccatcgataa attctgcaat cataggtcac
    27541 ctccattgaa aaagagttga ttaccgtaag cttcttttag attggtttcg gtaaaagttt
    27601 cttttgttgg accaaaggca atcacttctc gattgacaag taagacttga tcgaagtagt
    27661 ggggaatctt gctgaggtcg tggtgaacga tgagaaccgt cttcccagct tttttcaaat
    27721 ctctcagcgt attcatgatg atttcctcac tgacagagtc aatcccagca aagggttcat
    27781 ccaagaggat atagtcggct tcctgcacca aacatctggc aatcaagacc cgctggaatt
    27841 gacctccaga cagttgacta atttgacgtt cagcgtagtc agctaggccg acgatttcaa
    27901 gggcctcttg cactttcttc caatgtttag cctttaaact tcgaaagaga ggaatagagg
    27961 gaaatagtcc taacgagacg cattccttga ccttgatggg aaagttgtag tcgatattga
    28021 ttttttgttc gacataggca attcggtgta aggatttttt aacttccttg tcatcgagaa
    28081 atgcctgacc ttgatgtggg ataattccca gcataccttt taatagtgtt gatttcccag
    28141 cgccgtttgg accaatgatg ccggtaattg ttggtccatg gagcactagt gaaatatcct
    28201 taagtgccaa cgtttctttg taggagacac tgaggttttc gatacgtatc ataaacttgt
    28261 attcctcctg tctcttaata tacattaaaa aaaaaattaa gtcaagttaa tttttgaaaa
    28321 aattaaaata ataactgaaa aatagattct aaagataact ttcaggataa atttctaaat
    28381 tataaaacgc atagtatcaa gtgtaaaaaa cttggaatta tgcgttttat catggaaaga
    28441 ttttttataa tagctaaaaa ataatagtta aatggttatt aattgcattc cctagtgatt
    28501 tttgttaaga taaatgcaaa tacaaatgaa agcgagaaca agatgacacg ttatcaagat
    28561 gatttttatg atgctatcaa tggaaaatgg caacagacag ctgaaatccc agcagataag
    28621 tctcaaacag gaggttttgt tgatttagac caggaaattg aagacctgat gctggcgaca
    28681 acagacaagt ggttagcagg tgaagaagtg cctgaggatg ctatcttgga aaactttgtc
    28741 aaataccacc gcctagttcg tgattttgac aagagagaag ctgacggtat cacacctgtc
    28801 ttaccactcc ttaaagaatt ccaagaattg gaaacttttg cggattttac agctaaacta
    28861 gcagagtttg agcttgcagg aaaaccaaac ttccttcctt ttggtgtatc gccagacttt
    28921 atggatgcta gaatcaatgt tctatgggct agcgctccaa gcacaatctt gccagatacg
    28981 acctactatg cagaagaaca tcctcagcgc gaagagctct tgactctttg gaaagaaagc
    29041 agcgcaaatc tcctcaaggc ttatgatttc tctgatgaag aaattgaaga cttgctagaa
    29101 aaaagacttg aattggaccg ccgagttgcg gcagtggtgc tctctaatga agaaagttca
    29161 gaatatgcta aactctatca tccatattct tacgaagatt tcaagaaatt cgcgcctgcc
    29221 ctacctttgg atgacttctt caaagcagtt attgggcaat taccagacaa ggttattgta
    29281 gacgaggaac gtttctggca agcagcagag caattttaca gtgaggaagc ctggtctctc
    29341 cttaaagcaa ccttgatttt gagtgttgtc aatctttcaa ccagctattt aacagaggat
    29401 atccgtgttt tgtctggtgc ctacagccgt gccctttctg gagttccaga ggcaaaagat
    29461 aaggtcaaag cagcttatca tctagcacag gaacctttca agcaagccct ggggctttgg
    29521 tacgcccgtg agaagttctc tccagaagcc aaggcggatg tggagaaaaa agtggcaacc
    29581 atgattgatg tctataagga gcgtctgctt aagaatgact ggctcactcc agaaacctgt
    29641 aaacaggcta tcgtgaagct caatgtgatc aaaccttata ttggctatcc agaagaattg
    29701 cctgcacgtt acaaggataa ggtagtgaat gaaactgcca gtctttttga gaatgctcta
    29761 gcctttgcgc gtgtggaaat caagcacagt tggagtaagt ggaaccagcc tgtagactat
    29821 aaggaatggg gcatgcctgc tcatatggtc aatgcctact acaatcctca gaagaacctg
    29881 attgtctttc cagcggccat tttacaggcg cctttctatg acttgcatca gtcatcttct
    29941 gctaactacg gtggtattgg ggcagtgatt gcccatgaaa tttcccacgc ctttgatact
    30001 aacggggctt cctttgacga aaatggtagc ctcaaggatt ggtggacaga gagcgactat
    30061 gctgccttca aggagaaaac acaaaaagtc attgaccaat ttgatggaca ggattcttat
    30121 ggagcaacca ttaacggtaa attgactgta tcagaaaacg tggctgactt gggaggaatc
    30181 gcagcagcgc ttgaagcagc taagagagaa gcagacttct cagcagaaga gttcttctac
    30241 aacttcggtc gcatctggcg catgaaaggt cgaccagaat ttatgaaact tttggctagc
    30301 gtcgatgtgc acgcaccagc caaactccgt gtcaatgtgc aagtaccaaa cttcgacgat
    30361 ttctttacaa cctatgatgt caaagaagga gacggaatgt ggcgttcacc agaggagcgc
    30421 gtgattattt ggtaatacaa aaaatctagt catcagaaaa aaggcatcca atcacgtgtg
    30481 aaaaccttga taggatgcct tttgtaatag aaagatttgc tggatagttt acttaaattt
    30541 cgattgtcat catcttgcta gaaaaaggga ttgaaggcct tttcgtgagc gatagtagta
    30601 gctggaccat gtcctggata gacatcgtag tttggtaggg tgaagagttg ggtctggata
    30661 ctatgaagga gttgctccat gctaccagtc ggaaggtcgg tccgtccgat agtttcgcgg
    30721 aatagagcat ctcccgtcaa gactaggtga gcatcaggaa agactaggga aacaccaccg
    30781 atagagtgcc ctggggtcgg tagaacctta aaacgaaatt cctctagttg gtattcttcg
    30841 tgaaagacaa aggtgtgttc tgcaggtttt gtgaccacat ctgccatatc atcgtggcga
    30901 gggagaccgg agagattatc gacaggagtg tagagccagc tggcttcgct ctctgcgata
    30961 tagacaggag gattgccaaa cgtctcgcga accaagtcca gactcatgat atggtcataa
    31021 tgggcgtggg tcaagagaat agcacagatc ggtttgttga tcttctcgat tgtctgacga
    31081 atggcttccc aatgactacc aggatcgacg acgatgaggt gcttttcgcc ttctagataa
    31141 taggtatttt cataggcaac aggattcacg gttttatgga ttttcatact aactccaatc
    31201 tcaaagaatg tactaatact cttcgaaaat ctcttcaaac cgcgtcaact ttatctgcaa
    31261 cctcaaagca gtgctttgaa cagcctgcgg ctagctttct agtttgctct ttgattttca
    31321 ttgagtataa attaagtata gcacagttag ggagaatagg taaggattta aaatgaactt
    31381 aaaaaccagc atgactagat gaagacaggc tggttatcaa tttatcaata ttggaaaggt
    31441 gtcaattgcc cttcataggt tgcataaact ccgtcattag cttgtttgat agacgtgatg
    31501 tttagagtgc taccgtagtt ggcttctcat ttgtcgctat attcactata agttatccta
    31561 ctgggcaggt tctggtcgtt agcatagtat tgaacgagtt ttttatagct ttgctggctg
    31621 aataggaaca ggcagcaaac tcctaacatt aggagagcaa agatagaaat agcagttttt
    31681 tcataggtat tctccttata aactaaagga tagaagaaag tatcttgagg atttttatac
    31741 tcttcaaaaa tctcttcaaa ccgcgtcaac gtcgccttgc cgtatatatg tgactgactt
    31801 tgtcagtctt atctacaacc tcaaagcagt gctttgagca acctgtggct agtttcctag
    31861 tttgctcttt gattttcatt gagtattaat tccaaaatcc agtcaaggta ccagtgtatg
    31921 tgatacgagt tccaccgttt atctttcgta tcttcaatgg aattggggaa atcagaaagt
    31981 ctttgggtta caatatggtt tccgttcttc tatctctcct tctatcacct aagtttaaaa
    32041 tctaacttcg tagtatatta tgggccaata attcagaatt atcaagcaat tttgaattat
    32101 ttttttctta ttctgttcca atctagtttt catattctta aaaaagtgat aaaatggtag
    32161 gaagaattgg agagtagaga tgccgaaaga agtgaattta acaggcgaag aagttgtcgc
    32221 tttaaccaaa gaatatttaa cggaagagga tgttcatttt gtccataagg ccttggtcta
    32281 tgctgttgaa tgccacagtg gtcaatatcg caaatcaggc gagccttata tcattcaccc
    32341 tatccaagtg gcaggtattt tagctaagct aaagctggat gctgtaacag tagcttgtgg
    32401 attcttgcat gatgtggtgg aagatacaga tgcgaccttg gacgatttgg aaagagagtt
    32461 tggtcctgat gtgcgggtga ttgttgacgg agttaccaag cttggcaagg tcgagtacaa
    32521 atcgatcgag gagcaattag cggaaaatca tcgcaagatg ctcatggcca tgtctgagga
    32581 catccgcgtt attttggtca aactgtctga ccgcttgcac aatatgcgga ccctgaaaca
    32641 tcttcgaaaa gacaagcagg agcgtatttc caaagaaacc atggaaatct atgccccact
    32701 tgcccatcgt ttggggattt ccagtgtcaa atgggaatta gaagacttgt ctttccgtta
    32761 tctcaatcca acggagtttt acaagattac ccatatgatg aaggaaaagc gcagggagcg
    32821 tgaggccttg gtggatgagg tagtcacaaa attagaggag tatacgacag aacgtcactt
    32881 gaaagggaag atttatggtc gtcccaagca tatttactca attttccgca aaatgcagga
    32941 caagagaaaa cggtttgagg aaatctatga tctgattgct attcgttgta ttttagatac
    33001 ccaaagtgat gtttatgcca tgcttggtta cgtgcatgaa ttttggaaac cgatgccagg
    33061 tcgcttcaaa gactatattg ccaaccgcaa ggccaatggt tatcagtcta tccatacgac
    33121 tgtttatgga ccaaaagggc cgattgaatt ccagattcga accaaggaaa tgcacgaggt
    33181 ggctgagtac ggggttgcgg ctcactgggc ttataagaaa ggtataaagg ggcaagttaa
    33241 cagcaaggaa tcagctattg gaatgaactg gatcaaggag atgatggagc tccaagacca
    33301 ggctgatgat gctaaggaat ttgtggactc tgttaaggaa aactatttgg ctgaggagat
    33361 ttacgttttt accccagatg gagctgtccg ttcccttccc aaagattcag gaccgattga
    33421 ttttgcctac gaaatccata ccaaggtcgg tgaaaaagca actggtgcca aggtcaatgg
    33481 ccgcatggtt ccactgacaa ccaagttaaa gacaggggat caggttgaaa ttatcgccaa
    33541 cccgaactcc tttggaccta gccgtgactg gctcaatatg gtcaagacta gcaaggcgcg
    33601 caataagatt cgccagttct ttaaaaacca agataaggaa ttgtctgtca acaagggtcg
    33661 tgagatgctg atggctcagt tccaagaaaa tggctatgtg gcaaataaat ttatggacaa
    33721 gcgccacatg gatcaagttc tgcaaaagac cagttacaag acagaagact ccctctttgc
    33781 ggccattggt tttggggaaa tcggtgcgat taccgtcttt aaccgtctga ctgaaaagga
    33841 acgccgtgag gaagagcgtg ccaaggccaa ggctgaggca gaggagcttg tcaaaggtgg
    33901 cgaggtcaag gttgaaaata aagaaactct caaggtcaag catgaggggg gagtggttat
    33961 tgaaggtgct tctggtctcc tagtgcggat tgctaagtgt tgtaaccccg tgcctggtga
    34021 cgatattgtt ggctacatta ccaagggtcg tggtgtggct attcaccgtg tggactgtat
    34081 gaacctgcgt gcccaagaaa actacgagca acgtctcctt gatgtggaat gggaagacca
    34141 gtactctagc tcaaataagg agtatatggc ccatatcgat atctacggtc tcaaccgtac
    34201 aggactgttg aacgatgtac tgcaagttct ttcaaataca accaagaata tttcaacggt
    34261 caatgcccaa ccaaccaagg atatgaagtt tgctaatatc catgtgtcct tcggtattgc
    34321 caacctctct acactgacca cggttgtcga taaaattaag agtgtgccag aagtttactc
    34381 tgtcaaacgg accaacggct agttgtccta gctcttacta gaaaggctat tatgaaaatc
    34441 attatccaac gggttaaaaa agcccaagtg agtatagaag gccagattca gggaaaaatc
    34501 aatcagggac ttttattgct ggttggtgtt ggaccagagg accaagagga agatttggac
    34561 tatgctgtga gaaaactggt caatatgcgg attttttcag acgcagaagg caagatgaac
    34621 ctgtctgtca aagatattga aggagaaatc ctctccattt ctcagtttac cctctttgcg
    34681 gatactaaga aaggcaatcg tccagccttt acaggggcag ctaaacctga tatggcatca
    34741 gacttctatg atgctttcaa tcaaaaatta gcgcaagaag tgcccgttca gacaggtatc
    34801 tttggagcag atatgcaggt tgagctggtt aataacggac ctgttaccat tatcctagat
    34861 actaaaaaga gataagaaag accaagccca gtcggcttgg tctttctcat cgatcataaa
    34921 atactccaaa aagaaatcgg ttcttgatat gcttggggga agtctctttt caggctttgg
    34981 cagatgcgat aggaagggat gagatgtcct aggatgagga gagttccctg aaggaaaagt
    35041 ggaatatcac ttaaagacac caaggagaga atcatcaggc tatcccatag gaaaatttgt
    35101 aaagcaaaac gccagaatct cggtctaatc tgggaataga gttgactaaa gtggtcacaa
    35161 agttggtttg aaagataggt caatagcacg ggatgaaaga aaatgagcca accactataa
    35221 atcaaaatcc agtcccaagt aagcccccct tttaaatgtc aaaaatacca gcatgattcc
    35281 atcaatgaca aggagttgaa tggttttgat gaagatgatt tttttcatgc taaaacctcc
    35341 ttttccttag agacactccc ctacaggtat tttagaatgt atattgctta gatattcctt
    35401 attttattag ctttttaagg tattaaagta gttatataag tttatgaagg gtatcctatc
    35461 ctgcacggct aattttgagt tcgaaactga ggagtttata actcaaaatt tcgattaaat
    35521 cagcatttaa cgatagtatg tttgtcataa aatgataaat ttttagattg tggaattttt
    35581 ttcaacttaa ttcttgattt tttttctaaa ttgttatata cttaatttac gggataacag
    35641 aatcccgtca gaaaggggtg ataatatggg aaaagagaat gttagaatgc gtttagcgtc
    35701 tgaatccaga cagatattag ataagcttaa agatgatgtt tacaataaat taggctatga
    35761 agtaagctat tccagtattg ttagtcaagc tgttagagaa tacgttccta aaaaagaacg
    35821 tatagattgg ataaaattaa aagagacagc tatacctttt tcatcgttaa aacagagcaa
    35881 taattgggag taccagacat cacttatgtt agagaaagat gtattaatct tactgtctga
    35941 actacaaaat tttttcttag atgtcttcca agcgaaacgt atacataggg cattttgtat
    36001 acgtctatgt ttgagagcgc aatttttatt aagtaataat gattcttaat actatcaata
    36061 ttaatgcgga gtgtaatgct ccgcaaaaat aaaacctatt acgggataaa aacactactt
    36121 tatttaggat ggaaataaga acgtattttt tactaatatt gtttagaaag gagtttcttt
    36181 atgacaccag aagaacaaac tgctttggaa tacttttatg aggaactcga gagttacggt
    36241 gaagatgagc aaggagaggt ctttgatttg tatgataatt aaatcatctc catagtttct
    36301 gagaataatt gagaaactat actctaaatc ataggtttat gtaaagctag atatacacaa
    36361 aaggaggtac gaatgaagat gaaagctaga gcttcaccgt tgaattgatt ttgtttctag
    36421 aaaaaatcaa taattagaaa aatacgaggt aaaaaaatga atagaaatgt actaaatttt
    36481 ctgcgaacag aaagtgctga aagagttagt ctttatatag acaaggctaa tagattggag
    36541 ggcgatgtaa ctctactcgc acctagttct caagatttgg aagatattaa aaatgctatg
    36601 ttttccaatc ctaatctcga gctaaaagta gcgagactgg atgtgatgaa gaaaatagca
    36661 tatgcttcta caagaaatca ttatttaaca ggggctacga tttttgggga tatttcgaaa
    36721 ggaacataca attgtgatcc taaaagttat gtctaatata agggaggtta atccctcccc
    36781 ttgtttttga aaatcgaaag gaaaagtata aaaatgaaag ttaatgaata tttctggaga
    36841 acgagctgtc ttatactaaa aaagaagaaa tcgataaaat agtatacgtg ttagagatgt
    36901 gtttgtcgta aaagtctgga tagttttctc ttaggtagtc agctgtcata taataaaaag
    36961 tagaatggca agcagtgatg attggcataa gagatgaaaa acgctgagaa ctaatgaagg
    37021 ctaagagaac aaaaaataga aaatcaatgg tgagaacccc taaatagtag aagcgaatct
    37081 ttttattgat ttgaggataa atctcagcga attgatgttt gagtcggacg accaagagaa
    37141 atagcaggag tccttgagca aggaagaaaa ttaaaccaga gagcaagagc cactcaaaag
    37201 atgtctcgag tctagtgata aaaaatgcaa atagtagcaa atcaataact gcaattgcta
    37261 taaaatggat tctatagagt tttttcatga caagacctcc ctcttttatc taacttcatt
    37321 ctactctaaa agaatgggag ttacaactaa aatgataaaa atagcagagg ggagattctc
    37381 ttaagttggc tagtattctt tatttgagtt tccttctatt atctaacttc ttcatcattc
    37441 cagacaaata aagctccgat tgcattgagg atataaaaga tgtatttacc gatattggcg
    37501 aagtttcctt gaataccagc ttttgtcagc tgaacgaaat tgtaaatcaa ccaaaagccc
    37561 cactgagttg ttagttttaa tgcattcaaa gcattggcaa tgagggacag tgcaaaggca
    37621 atagttgtta cgtaggcaag gagattcatc ttgcccccat atccgatata gttggtcaca
    37681 aaggcaaaga ggaaggcgat gatggaaatg atgatggccg ccaattttac ctgtttttgg
    37741 ctcatttggt tgggtctgcc ttcttgcgaa gctttccatt tctttatagc aaaggtataa
    37801 atgaggaagg tgacgggata ggtaatgatg gccgccttat ttccaaggat ataatcaata
    37861 gcaccggaca aaatggtatt aacaatacca aagtaatttt cccatttgct taatttcccc
    37921 gtgaaacgag tggacaacat ggaaatccca acgttggtta cggaaatcaa tccaaagggt
    37981 acaagagctg tccatggtcc ccagtctaca aatttatcga ggcgtgagtt gaggtaacca
    38041 gatgcaatcg caatccaacg accaaagcaa ccccgaagag gtcaaactat ttagatgtag
    38101 caaaaatttt tagtgatttt ttcataggtt aaactacctt tctttttttc aaatattctc
    38161 ccattttttt tcaaatattc taccaccaaa tgaaagtaaa ataaaatgat agaaataaaa
    38221 ccctgaaaat aaaactttca gggttggtag gggacttgag aaattagttg attttctcga
    38281 catagagttg ttttgcaatg tccatattca cttgtaaatc ctcgtcgtta ctgaggatag
    38341 tgaaggtatt gctgaagcca tcaaactgct taacttggag ctggtcaccg atgtgaagtg
    38401 agtgcttgtc cagataatgg agaatgtcaa aactatcgtg catccgagtc aggcggtagg
    38461 cgccagcttc cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct
    38521 tggcaggaat agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc
    38581 tttccacgaa caggtcagag acagtgtgtt ccaagatctc agcttcctcg tgaatctggt
    38641 cacttgtata gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga
    38701 gctcagagac cagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta
    38761 ggatgagatt ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt
    38821 gcatgcgagc cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa
    38881 tacattttag atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta
    38941 tctagtatat caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg
    39001 caagagaaaa aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg
    39061 aaataccacc gccttggagg ctgttttggc agatgctcgg cagctaggag tggatgaata
    39121 ctggcttttg ggagatattc tcatgccagg gacagggcgt agaaggattt tggacttgtt
    39181 ggatcaacta ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg
    39241 tgtccgtaag gaattggata gtactcgccc tagtcaacgc tatctcttgc gccagtgcca
    39301 gtatgtttta gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca
    39361 aattcatcgt cagtttgggg atttgacagt gggaattagc catcatctgc ctgataagaa
    39421 ctgggggcga gagttgattc atactggcaa acaagaggaa tttgaccgct tggtgactca
    39481 tcctccctgt gatattgctg tttatggaca cattcaccag cagttgcttc gttacgggac
    39541 tggtgggcaa ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca
    39601 gctacggaag gacttgcggg cccagtatat gattttggag tttgatgaca agggcctggt
    39661 agatatggac ttccgacggg tagattacga tgtggcagct gaattgcagc tggctaaaga
    39721 cctgagactt ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac
    39781 tcatcatcag gaatttttga gagaattggc tcagaaagag ggttgcgatc gggagttaga
    39841 cgactggttg aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa
    39901 aagaagagta gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag
    39961 atttaccatt gcgactcata tgctgataat cattgccctc gaggggaaga aaagcaaggt
    40021 gaccagtgat tttctggctg ctagtgtcgg ggtcaatcct gtcattatca gaaagatctt
    40081 gtcccagttg aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagatat
    40141 tgtcaaggac cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg
    40201 taagacaggt caactcttca gtttccatga caatccgaat ccaaattgcc ctgtaggagc
    40261 tcatattcat gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga
    40321 acttggtcaa accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta
    40381 agagggataa atgccctctt ttttctttgg ataattatga taaaatgtag ctattaaagg
    40441 agtaagaaat gtatctcgtt ataggaattg tattagcctt tatagtgtca ttttggaagg
    40501 ataatagaag tttgtggaat ccagtattat ttttattatc cctcatttca agttattttt
    40561 atctatccta ccttttttat aaaaatggat acgagaatgt tcagttagct ttttatgtat
    40621 ttgcctttgt cttacttcct tttttgcttt ttctaagtgg catcttttta atctataatg
    40681 gggtcatttt gttgaagcga gagggacgtt ccaagcccca ttatctctca atgctctttg
    40741 atttttattg actattagat tctatttaaa aagacttaga atgcacatga aagtatgtat
    40801 tctaggtctt ttgttttgta tacatttaat tttcaagagt attatctatt tttccatgcc
    40861 tggtaacgag tatcaatcaa taactgggta aggcgaccca aggtttctct ttcttctgga
    40921 gtgagggatt gagcttggac aaagagatga tgaatgtatt caagcgcctt taaggaagcc
    40981 aagtcattga tagagctaat accagcctca agaatagtgc caaagaagag gtcgaagtag
    41041 agctgaagtt cttcgtcagg gactgtggcc acccattctt taaaggttgt gtctacttgc
    41101 tggctatcac tgttggtctt atccagttgg acgaagtgct tgtcctcaat ctgccaacta
    41161 aaggtatcgt gctgggcgat gccacccagg gcagtactct gaacgatgat ttggtgagca
    41221 ggaatttcca gcatcatacc gataatggaa ccttgtggaa tgaatatctt gcttctatcc
    41281 attatccttt gataacccgc agtctgtgtc aattcttgat ggagaccagg tgcatcaaat
    41341 gtataaactg ctgtgatctg attttgcaaa ctttgctcaa tttggctagc agcatagata
    41401 gcgagatttc ctcccttgga atgcccagct agaataacct tttgcttagg atgatgggca
    41461 aaaaagttct ttaaatagcg aagggcgtgc ttttgagcag gaatttcctt catataggtc
    41521 aggtggaaat cttccttcca gccaatgata ctgtcatctg tcccacgaaa gacaatcaga
    41581 taggtatcga ggctgacacg ataagtcata gccgcaaatt gcttttgcag ttcagggtcg
    41641 atgtcgttga taaaatggga gagtttgcaa tttttgaagc gcttgtgttg agccaattta
    41701 tctaataatt gaaggcgatt tttgctagta agcatggtgg gctctcttgg aacctgaggt
    41761 gctagatcta aaagacgttg aggaagtgtg gagaccagat tatcaaagga gaggtaggtg
    41821 atttctatta aggttagaat gtctaactca ttcaagggaa ggtcgtaata agaatcatat
    41881 gcgacatctt tcagatagtc aaaaatattg gccataagag ctcctttctt tttatttatc
    41941 ttagcaaatt tccctcaaat tagctagtag catagcctgt ttgcactggc taaaaacagg
    42001 ctatttcaaa ttcagtttca gaccatctag catggaaaaa tctgttataa taatggaaaa
    42061 ggagaagcgc atgcacaaga ttttattaat agaagatgat caggtcattc gtcaacagat
    42121 tgggaaaatg ctctctgaat ggggatttga agtggtcctg gtagaagact ttatggaagt
    42181 tttgagtcta tttgttcagt cggaacctca tctggtcctc atggatattg gtttgccctt
    42241 gtttaatggt tatcactggt gtcaggaaat ccgcaagatt tccaaggtac ctatcatgtt
    42301 tctttcttcg agagaccagg ctatggatat tgtcatggca atcaatatgg gggcggatga
    42361 ctttgtgacc aagccttttg accagcaggt tcttttagct aaggttcagg gcttgttgcg
    42421 tcgttcctat gagtttgggc gtgatgagag tttgctggaa tatgctggtg ttatcctcaa
    42481 taccaaatcc atggatttac attatcaagg gcaagtcttg aatttgacca agaatgaatt
    42541 ccagatttta cgcgtgttat ttgagcatgc aggcaacatc gtagcacgtg acgacctgat
    42601 gcgggaactt tggaacagtg actttttcat tgatgataat accctctctg tcaatgtggc
    42661 tcgtttgcgt aaaaagttgg aggagcaggg attggtagga tttatcgaga ccaagaaagg
    42721 aatagggtac ggattgaagc atgcttgatt ggaaacaatt ttttctagcc tatctgcgct
    42781 cccgtagtcg tctttttatc tatctgcttt ctttggcatt tcttgtctta ctctttcagt
    42841 ttttatttgc cagtctagga atttacttcc tctacttttt cttcttgtgt tgctttgtaa
    42901 ccatcttatt tttcacttgg gacatattgg tggaaatgca ggtctatcgc caggaacttc
    42961 tctatggaga gagggaagcc aagtctcctt tggaaatagc tttagcagaa aaattagaag
    43021 cgcgtgagat ggaactctat cagcagaggt caaaagcaga aagaaaactg acggatttgc
    43081 tggattacta taccttgtgg gtccatcaga taaagacccc cattgcagcc agtcaactct
    43141 tagttgcaga agtggtcgac cgccaactga agcagcagct agaacaggaa attttcaaaa
    43201 tcgactctta taccaaccta gttttacagt acctgcgttt agaaagtttc catgatgatt
    43261 tggtcttaaa gcaggttcaa attgaggact tggtcaagga aataattcgt aaatatgctc
    43321 ttttctttat tcaaaaaggc ttaaatgtca atctacatga ccttgataaa gaaatcgtga
    43381 cggataaaaa gtggctgcta gtggttattg agcaaatcat ctcaaacagt ctcaagtaca
    43441 ccaaggaagg tggtctggag atttatatgg atgaccaaga gctttgtatc aaagatacgg
    43501 gaatcgggat aaaaaacagt gatgtcctcc gagtatttga acgtggcttt tcaggataca
    43561 atggccgttt gacccagcag tcctctggac ttggccttta tctatctaag aaaatttctg
    43621 aagaactggg gcaccagatt cgtatcgagt ctgaggtcgg aaaaggaacg acagtgcgga
    43681 ttcagtttgc tcaagtgaac ttagtccttg agtaaaaata gatgagaaaa agcctccaga
    43741 ttggaggctt ttatgctaga ctcttatttc tcaacgcgtg atttgttggc gatatcagct
    43801 aggatagctt gaacaaaatt atcaactgag acagtttgtg tttctttttg gccgtagcga
    43861 cgaacgttga ctgtttcgtc ttccatttct ttgtctccaa caattaattg gtaaggaatc
    43921 ttgctggttt gtgaagcacg gatcttgaac tgcatttttt cattgcgctc atctacgtct
    43981 gcacggacac cgcggtcacg gagtttcttg gctacttccc aagcgtagtc cacgtgtttt
    44041 tcgttagata ctgggataag ggttacttgg tgtggtgcca gccatgttgg gaaggcaccc
    44101 ttgtagttct caatcaagat agctgtgaag cgttccatag ttgagataac cccacggtgg
    44161 atcatgactg gacggtgatc ttcgccatca gctccgatgt atttgaggtc gaagcgttct
    44221 ggcaacaaga aatcaagttg gatagtagaa agggtttctt cttttccaag ggcagtttta
    44281 atctggatat ccaattttgg tccgtagaag gccgcttcac cttcggcttc aaagtagtcc
    44341 acgcccattt catcaagagc tgcacgaagc atggtttggg cattttccca catctcatcg
    44401 ttatcaaagt acttatgagt atcttgaggg tcacgaagag agaggcggaa gcggtagtca
    44461 gtcaagttga agtcttcata aacatcgata atcaactgaa gggcacgttg gaattcttct
    44521 tggatttgtt ctggagtaac gaataggtga ccgtcgttga gtgacatttc acgtacacgt
    44581 tgaaggccag tgagggcacc agatttttcg taacggtgca tcataccgat ttcagcgata
    44641 cggattggca attcacggta agagtgaaca tggtgtttga aaacttggat gtggtgcgga
    44701 cagttcattg gacgaaggac aaattcttcc ccgtcaccca tgtccatggt tgggaacatg
    44761 tcttcttggt aatgatccca gtggccagaa gtcttgtaaa gctcaacaga agcaagtggt
    44821 ggagtgtaga cgtgttggta gccagaagcc aactctttgt ttacgatgta gcgttccaat
    44881 tcacgacgga tagtcgcacc atttggcaac cagaatggca aaccttgtcc cacttcttgt
    44941 gaaatcataa agaggtcaag ctctttacca agtttacggt ggtcacgttc cttagcttct
    45001 tcacgcattt gaaggtagtt tttcaagtct ttcttttcaa accaagctgt accgtagata
    45061 cgttgcatca tagcgttgtc gctgtttcca cgccagtacg caccagctac atggagaagg
    45121 tggaagattt ggatacgacc tgttgatgga acgtgaggtc cacggcagag gtctacatat
    45181 tcaccctgac gatagatagt caaaccgcct tcgtcttctg agtgttcttc aatcaattcc
    45241 aacttgtaag ggtcattttt gaagatttca cgtgcctcgt ctttagtcac ttcttcacga
    45301 atagatggga agttttcttt gacgattttt tgcatttctt cttcgatacg aggaaggtct
    45361 tcgttagaga tttgaccagc tgtgttgtca gtatcgtagt agaaaccatc ttcgatggct
    45421 ggaccaactc ccaagtgaat gtctgggaaa agacgacgag ctgcttgggc gaacaagtga
    45481 gctgctgagt ggcgcaagat tggaagggca tcttcgtgat caggtgtcac aatttcgatg
    45541 cttccatctt cagtgatagc gcgagtagtg tcgatgagtt tgccgttgaa tttaccagcc
    45601 aaggcttttt tagctaggga attgctgata gattgggcaa tttcaaaagt tgttacgcca
    45661 gattcgaatt cacgaacagc gccatctggg aaagtaatgt taatcatgat gttctccttt
    45721 tttattattt catagtttct aagcattgat tttttatcat cagactactt ccaagtccta
    45781 acgttcaatt gcttttcttt atcagagagg aagttttcca tttccgtcag aatgtctata
    45841 tccaaacgtt gagaaagttc taatagccac cagatatttt ctgaaagttt ttgttccagt
    45901 gtgtagggtg tttcatcata gtagcgtcct tgctttgtca tcaccagtcg ttggaaattt
    45961 ccaatatcat tagataaagc caaggggtct tcttctaccg tccacttgga atcatgatgc
    46021 ttaacttcca gttcgtgata agcttgtcgg attgcccaac tgcgctccac taattcttgc
    46081 aactccataa ttagtatcct aataaaaaaa tgcgacatcc tcgaaaggac gtcgcaacgt
    46141 ggttccacct tcatttatgt acctcaaaag agagggacac ctctgattgg ctctaacgtg
    46201 gccaccgttt tatgttttca taaaaaactc aagagtagta tcagtttaga cttcctatgc
    46261 gtttccagca accacgcact ctctagtaga aagggactaa gtgacttgtc tctatggatt
    46321 attatagcat gattgtgaga tttttcaagg attttgtgaa agttttttgt ttttcatttt
    46381 ttgtagaata tgcttgatgc taataccaga atccatgccc accagagcaa ctgtttcata
    46441 gattagcaag taaattagta taaactcacc aaaggttatg atagtaaagt aaaagagcag
    46501 tccgttacca actaaccatc aaagtgagaa acggaaacgg tagctataga gtaacgatac
    46561 aatcaagatt accagaggtg taaagaagag aagattgttt atatagagtt ccttgagtgt
    46621 aagggggtca gaaacaacta gtaagaacaa ctcataaagt ggccaataaa agaataatat
    46681 gaccagatag taggggagat gggaatagaa tctacgcatg ataatcacct cgttttaaaa
    46741 aaacagacaa cttagatctc ttgctatgat tattatagca tgtttaaaac aagaaagtaa
    46801 atttgttggc aaagaagatt tttttttcac tagaatcatg gttagttttc ttggtagaaa
    46861 tattttgata ataattaagc aaaactattg acattgatta ttaagagtgt cacaattgtt
    46921 gtaactaaaa taattacaat aagagaggta taaaaaatga aactagcagt tattgcagca
    46981 aatggacaag cggggaaagc aattgttgaa gaagtagtca aacgaggaca tgaagtaacg
    47041 gctattgttc gttctgaaaa caaaagtcaa tctgagtcta ttattaaaaa agatttattt
    47101 gagttgacaa aagatgatct tactggattt gatgctgtta tttcagcgtt tggtgcttat
    47161 acaccagata cgctaccgct ccacagcaaa tcaatcgaac tatttaatca gcttcttgct
    47221 ggaacacaga cacgttttct agttgtaggg ggagcaggaa gtctttatat agatgaaaca
    47281 aaaacgacac gacttttaga tacgtctgat tttcctgaag aatttaagtc actagcaaaa
    47341 gctcaagcgg atgaattgga tcttcttcgt acaaaaaata atctcaactg gacttttgtc
    47401 agtcctgctg tagattttat tcccgatggt gaaaaaacag gaaactacat tctagcagga
    47461 gaaattttta ctactaatga aaaaggaata agccagatta gttatgcaga ttatgctatt
    47521 ggattggtag atgaacttga aaaaggtcat catataaaag aacgtatctc tttacttgaa
    47581 aaataataac tatgagagta ttaatgtttg acagaaaatt taaatcttgg taaaataggg
    47641 attgtcgtaa agacaaataa cttcttcttg gttacaggca tgccaacctg tcactcggat
    47701 gaagccaaat aaaaaggaga aacatcatgg caatctcaaa agagaaaaaa aatgaaatca
    47761 ttgcacaata tgcacgtcac gaaggtgata caggttcagt agaggttcaa gttgctgtcc
    47821 ttacttggga aatcaaccac cttaacgaac acatcaaaca acacaaaaaa gaccacgcta
    47881 cttaccgtgg attgatgaaa aaaatcggtc gccgtcgtaa cttgcttgca tacttgcgta
    47941 aaaacgacgt taaccgttac cgtgagttga tcaactctct aggacttcgt cgctaattca
    48001 agatacaaag gccgtcaaaa acacaaagca aaaataggaa aattgacgaa gaaacttcag
    48061 tttctaggag attttatctt ttttgccaag tgcttaggcc gtgttcaatt gagcatatct
    48121 tgataataaa gctactctaa attgggtagc tttgttgcgt tgtcacctta cctcgctata
    48181 ctcaagtata atcttcggtt acggttccta gcactgtaag gtaaaataaa ctagcttttc
    48241 tcccttcggg gagatttttt tgtttcactg aaagtttcgt acgatcttca cctcgtcccc
    48301 tagtctataa acgatttatc tagcaagaat catgatgcta agggcgtcaa aaatccgtat
    48361 gaaaataggg aaatgacaca gtgttcgatg agcacaagga gtttcatctt tttcactagg
    48421 attttagccc gggctaaaat cagctctctg acttcagagg gcttttttat tgaggtttta
    48481 tcggtaacaa ttttggagac tacaaaaacc tcaaatggta tcagctaatt acaccataaa
    48541 ggtgcgcagt tactcggctt ttcaagccga gtagctgtat gcaagccccc tagaagagcc
    48601 cactctttac aaagtaaagt atagtatgtt atactttaca tggaagtagt cactgaattc
    48661 cagttagaaa ttactttgta actacgtttt gaggaggagt aaaatgcttt cctacgttcg
    48721 acattaccca ctagcgatag ctaaattaat gtgtctgtgc tctcctaaaa tctgctgatt
    48781 tattactgac taatacagga ggtttttttt atgggacaga caatcatatc tgctattggt
    48841 gtttatattt ccaccagtat cgattattta attattttaa ttattttatt tgcacagcta
    48901 tcacagaata aacagaaatg gcatatttat gcggggcaat atctaggcac aggcttactt
    48961 gtaggggcga gtttagttgc tgcttatgtc gttaatttcg tgcctgaaga atggatggtt
    49021 ggattgcttg gtttaatccc tatctattta gggattcgct ttgcaattgt tggagaagat
    49081 gcggaagaag aagaggaaga aattattgaa agattagaac aaagcaaggc aaatcaactg
    49141 ttttggacag ttacattgct gacaattgcg tctggcggag ataatttagg tatctatata
    49201 ccttattttg cttcgttaga ttggtcacag accctcgtgg ccttgcttgt gtttgtaatc
    49261 ggcataatta tcttttgcga gattagtcgg gtgttatcct ctattccgtt aatattcgag
    49321 acaattgaaa aatacgagcg aatcattgtg cccttagtat tcattctact tggactatac
    49381 atcatgtatg aaaatggcac gatagagact tttctgatcg tgtagatttt tttgtttcac
    49441 taggatttta gcccgagctc aaatcagctc tctgattttc agggggcttt ttcattgagt
    49501 ataaatggac aatcttaaag ttactctatt gtagagtggc ttttgatttg attaggagat
    49561 tcttataaat atagtaaaat gaaataagaa taggacaaat cgatcaggac agtcaaatcg
    49621 atttctaaaa atgttttaga agtagaggtg tactattcta gttccaatct actatataaa
    49681 tgaaaacctt agctgtttgg ccaaggttca tttcttctat gcaagttctt ctcttttctt
    49741 atctgggttc cagatgaagc ttgcgataaa gctaaagatg atggttagga tagcgaggat
    49801 aatagcaagg atgagggcag ggatgcggat aaaccaccag agtggatttg gttttttatc
    49861 attgtgccat tgtttcgttt cttcgtccag acgttggaat tctgtttgaa tacgattggc
    49921 gactgtttca atgccttcat cattcatttt cttgatatct gagatatcga ttggatttcc
    49981 aaagttcata tcgacacgtt cacggctaat caagcccttc aaagtcatgg gaccggtgta
    50041 ggtaaccggc atgatacgga ccttggccat tttggcaatc agtgctgcgc cccccttgac
    50101 atcgtttgag tggcggctac cacttggaaa catgatgaga gagcggtcac tttttttgag
    50161 aacgttgata ggatatttga tggctgaggc gctgggattt tcacggtcga tgggaaaggc
    50221 gccacacata cgaatccacc aaccaaagat acggttggta aagagttctt tttttgccat
    50281 aaagatgaac tgttttggct tggtcgcaaa ggccatataa acaggatccc accaggtacg
    50341 gtgaggcgca actaaaatat aattttcatc ttgattagga attttatcag tattatgata
    50401 gtgagcattg ccattgatgg accataagag caatacaact aatccacgca aataagtata
    50461 aaacatgcga tctccttcga ttgttttctt gttattatta taccttatca aaggagggct
    50521 ggcaaacttt tcccttgact agatacatat ttaggatgaa attagaattc tgttaaaaaa
    50581 aatgatataa tagaatttat ggataaaaat aagattatgg gattaaccca aagagaagtc
    50641 aaggaaagac aggctgaggg tttggtcaat gactttaccg catcagccag taccagcact
    50701 tggcaaatcg ttaaacgaaa tgtctttacc ctttttaacg ctttgaactt tgccattgct
    50761 ttggctcttg cctttgtgca ggcttggagc aatctggtct tctttgctgt tatctgcttt
    50821 aacgcttttt ctgggattgt gaccgagcta cgagccaaac acatggtgga caagctcaat
    50881 ctcatgacca aggaaaaggt caaaaccatc cgtgatggtc aggaagttgc tcttaatcct
    50941 gaagaattag tgctaggaga tgtcattcgt ttgtctgcag gagagcagat tcctagtgat
    51001 gccttggttt tggaaggctt tgcggaagtc aatgaagcca tgttaacggg agaaagtgat
    51061 ttggtgcaaa aggaagttga cggcttactt ttgtcaggaa gtttcctagc cagtgggtca
    51121 gttttatctc aagttcacca tgtcggtgca gacaactatg ctgccaaact catgcttgag
    51181 gctaagaccg ttaaacccat caactcccgt atcatgaaat cgctggacaa gttggctggt
    51241 tttactggga agattatcat tccctttggt ctggctctct tgctggaagc cttgctttta
    51301 aaaggcctgc ctctcaagtc atccgttgta aactcgtcga cagctctttt gggaatgttg
    51361 cctaagggaa ttgccctttt gaccattact tcgctcttga ctgcagtgat taagttgggc
    51421 ttgaaaaagg tcttggtgca ggagatgtac tctgttgaga ccttggcgcg cgtggatatg
    51481 ctctgtctgg acaagacggg taccatcacc caaggaaaga tgcaggtgga ggctgttctt
    51541 ccgttgatgg aaacgtatgg tgaagaggct attgccagca tcttgactag ctacatggcc
    51601 catagtgagg ataagaatcc aactgcccaa gccattcgcc agcgttttgt gggagatgtt
    51661 gcttatccta tgatttccaa tcttcccttc tcgagcgacc gcaagtgggg ggctatggag
    51721 ttagaaggtt tggggacagt tttcttaggg gcgcctgaga tgttgctgga ttctgaagtc
    51781 ccagaagcca gggaggcctt ggagagagga tcacgtgtct tggtcttagc tctcagtcag
    51841 gagaaattag accatcacaa accacagaaa ccatctgata ttcaggctct agccttgctg
    51901 gaaatcttgg actccattcg agagggagca gcagagacgc tggactatct ccgttctcag
    51961 gaggtaggac tcaagattat ctctggtgac aatccagtta cggtgtccag cattgcccag
    52021 aaggctggtt ttgcggacta tcacaactat gtagattgct caaaaatcac cgatgaggaa
    52081 ttgatggcca tggcggagga gacagctatt ttcggacgtg tttcccctca tcaaaagaaa
    52141 ctcatcatcc aaacgttgaa aaaagcgggt catacaacgg ctatgacagg ggacggggtt
    52201 aatgatatct tggcccttcg tgaggcggat tgttctatcg tgatggcgga gggggatcca
    52261 gcaacccgtc agattgccaa tctggttctc ttgaactcag actttaatga tgttcctgag
    52321 attctcttcg agggtcgtcg cgtggtcaat aacattgccc acatcgcccc gattttcttg
    52381 ataaagacca tctattcctt cctgttagca gtcatctgta ttgccagtgc tttactaggt
    52441 cggtcagagt ggattttgat tttccccttc attccgatcc agattaccat gattgaccag
    52501 tttgtggaag gtttcccacc attcgttctg acttttgagc gaaatatcaa acctgttgag
    52561 cagaatttcc tcagaaaatc catgcttcgt gccctaccaa gcgctctcat ggtcgtcttt
    52621 agcgtcctgt ttgtgaaaat atttgggagt agccaaggtt ggtctgagtt agaaatctca
    52681 actctcctct attatctctt ggggtcaatt ggtttcttat ccgtatttag agcctgcatg
    52741 ccatttaccc tatggcgtgt cctcttgatt gtttggtcag taggaggttt cctagccaca
    52801 gctctcttcc caagaatcca aaaactgctt gaaatttcaa ccttaacagg acaaacatta
    52861 cctgtttatg gtgtcatgat gttggtcttt accgtgattt tcatcctgac cagtcgctat
    52921 caagccagaa aataaagaaa ggctgcaatc tgtggattgc agttttttta ggtacaagat
    52981 tgccagtcga aatgtggtat aataagaggt aatagagttt tggaaagtga gagaagatga
    53041 tttcaaagag attagaattg gtagcttcct ttgtgtcaca gggggctatt ttactagatg
    53101 tgggaagtga ccatgcttat ctgcctatcg agttggttga gagaggccaa atcaaaagcg
    53161 ctattgcagg tgaggtggtg gaaggtccct atcagtctgc ggttaaaaat gttgaggctc
    53221 acggcctaaa ggagaaaatc caagtccgtt tagccaatgg cttggcagct tttgaagaga
    53281 ctgaccaagt gtctgtcatt accattgctg gcatgggtgg tcgtttgatt gctaggattt
    53341 tagaagaagg tttggggaag ttagctaatg tagagcgttt gatcctccag cccaataatc
    53401 gtgaagacga cttgcgtatc tggctacagg atcatggatt ccagattgta gcagaaagca
    53461 ttttagaaga agctggaaag ttttatgaga ttttggtggt ggaagcagga caaatgaagc
    53521 tatcagccag tgatgttcgc tttggtccct tcttgtccaa agaagtcagt ccagtatttg
    53581 tccaaaaatg gcaaaaagaa gctgagaagc tagagttcgc cctcggacaa atcccagaaa
    53641 aaaatctgga agaacgtcaa gttctagtag ataagattca agctatcaag gaggtgctcc
    53701 atgttagcaa gtgaagtgat ccaagcttat gaagcctttt gccctcagga attttctatg
    53761 gagggagaca gccgtggtct gcaaattggc actttagaca agggtatcca aagggtcatg
    53821 gttgccctcg atattcgtga agagacggtg gcagaggcta ttgaaaaggg tgtggacttg
    53881 attatcgtca agcacgcgcc tatctttcgt cctatcaagg acttgcttgc cagccgtccg
    53941 caaaatcaga tttacatcga cctgattaag catgatatcg cagtttatgt cagccatacc
    54001 aatattgata tcgttgaaaa tgggctcaat gactggtttt gtcagatgct aggaatcgag
    54061 gagacgactt atctgcagga aacaggtcca gaacgtggaa ttggacgtat tgggaatatt
    54121 cagcctcaga cattttggga attggcccaa caggtcaagc aagtctttga cctagatagc
    54181 cttcgaatgg tgcattatca agagaatgat ttgcagaagc ctatttcaag agtagcaatt
    54241 tgtggtggaa gcgggcagtc tttctataag gatgctttgg caaagggggc agatgtctat
    54301 atcactggtg atatctacta ccatactgct caggatatgc tgtctgatgg cttgttagca
    54361 ttggatccag gtcactatat cgaagtgctt tttgtggaaa aaatcgcagc actccttact
    54421 caatggaaag agaaaaaagg ctgggaacta gagattttac ctagtcaagc atcgaccaat
    54481 cctttccgtc atatctagtt agaaagtgaa gacaatgaaa aaagttgcca ttattggagc
    54541 aggaattgtg ggagcaacag ctgcctacta cctctcgaga gaaagtgacc tagaggtgac
    54601 cgtttttgac catgagcaag gtcaagccac caaggccgca gcaggaatta tcagtccttg
    54661 gttttccaaa cgccgtaata aagcctggta caagatggcg cgcttggggg ctgattttta
    54721 tgtggattta ttagctgatt tagagaaatc aggacaagaa atcgactttt accagcgttc
    54781 gggagtcttt ctcttgaaaa aggatgaatc caagttggaa gaactctatc aactggctct
    54841 ccagcgcaga gaagaatctc ccctgatagg ccagttagcc attctggatc aagcatcagc
    54901 taatgaatta ttccctggct tgcagggatt cgacaacttg ctctatgctt ctggtggagc
    54961 gagagtagat ggccaactct tggtaactcg tctgctagaa gccagtcatg tcaagttggt
    55021 caaagaaaaa gtgactctga cactcttatc atcaggctac cagattggcg aagaggtgtt
    55081 tgatcaggtt attttggcaa cgggagcttg gttgggggac atgttagaac ctttaggtta
    55141 tgaagtggat gtccgtcctc aaaaaggaca actacgagat tatcagcttg cccaagacat
    55201 ggaagattac cctgttgtca tgccagaagg ggagtgggat ttgattccct ttgcaggtgg
    55261 gaaattatcc ttgggcgcta cccatgaaaa tgacatggga tttgatttga cggtagatga
    55321 acccttgctc caacaaatgg aggaggcggc cttgcctcat tacccagttt tagctagagt
    55381 gacttcaagg gctgagcgtg tgggaatccg tgcctatacc agtgatttct ctcccttctt
    55441 tgggcaggtg ccagaattgg caggtgtcta tgcagccagt ggactaggtt catcaggcct
    55501 cacaactggt cctatcattg gttaccatct agcccaactg atccaagaca aggagttgac
    55561 cttggaccct ctaaattacc caattgaaaa ctatgtcaaa cgagtaaaaa gcgaataata
    55621 ctcaatgaaa atcaaagaac aaactaggta actagccgcg ggttactcaa agcactgctt
    55681 tgaggttgtg gatagaactg acgaagtcag ctcaaaacac tgttttgagg ttgtggatag
    55741 aactgacgaa gtcagtaacc atacccatgg caaggcgacg ttgacgtggt ttgaattgga
    55801 ttttcgaaga gtataagcat tttactgaaa ttttatcagg tagtttagga tggcaaatga
    55861 cattccctgt caaaaatggt aaaataagaa aaaataatct gagaatcgag gaaaaaagat
    55921 gcaagaaaag attttggtaa ctggtggtgc cggttttatt ggaacccaca ctgttattga
    55981 attgatccaa gcaggccatc aagttgttgt ggtggataat cttgtcaata gcaatcgtaa
    56041 gagtttagaa gttgttgaaa gaatcacagg agttgagatt cctttctatg aggcagatat
    56101 tcgtgacaca gctaccctca gagatatttt caagcaggaa gaaccgactg gtgtcattca
    56161 ctttgctggt ttgaaggctg ttggcgaatc aacacgtatc cctcttgcct actatgacaa
    56221 caatatcgct ggaactgtca gccttttgaa agccatggaa gaaaacaact gtaaaaacat
    56281 catcttcagt tcttctgcga cagtttacgg ggatccgcac acagtgccca tcttggaaga
    56341 tttcccactt tcagtgacca acccatacgg tcgtactaag ctcatgctag aggaaatttt
    56401 gactgatatt tacaaagcag actcagaatg gaatgttgtc ttgcttcgtt actttaaccc
    56461 aatcggagcc catgagagtg gtgatttggg agaaaatcca aacggtattc caaacaatct
    56521 cttgccatat gtgactcaag tagccgttgg aaaattagag caagtgcaag tgtttggaga
    56581 cgattacgat acggaagatg gaacaggtgt tcgtgactat atccacgttg tcgatttggc
    56641 taagggtcac gttgcagctt tgaaaaaaat ccaaaaaggt tcaggactaa acgtttataa
    56701 ccttggaact ggtaaaggtt actcagttct tgaaattatc caaaacatgg aaaaagcggt
    56761 gggccgtcct attccttacc gcatcgtaga acgtcgccca ggtgatatcg ctgcctgcta
    56821 ctcagacccg gcaaaagcta aagcagaact cggttgggaa gcagaactcg acatcaccca
    56881 aatgtgtgaa gacgcatggc gttggcaaag caagcatcca aatggatttg aagactaaga
    56941 tgatgatttc aatcatcgtc ccttgtttaa acgaagagga agtacttcct cttttttatc
    57001 aggctctgga agctttactt ccagatttgg aaacagaaat cgagtatgtc tttgtcgatg
    57061 atggatcaag tgatgggacc ttggaactct taaaggccta tcgggagcaa aatccggcag
    57121 tccattatat ttctttctct cgaaattttg gcaaagaagc agccctttat gcaggcttgc
    57181 aatatgcgac aggagatttg gtggtggtga tggatgcaga cctccaagat cctcctagta
    57241 tgttgtttga gatgaaaaat gtactagaca aaaatgtaga cttggactgc gttgggacac
    57301 ggagaactag tcgggaggga gaacccttct ttcgcagttt ctgtgctgtt ctcttttatc
    57361 gcctcatgca aaaaatcagc ccagtagctc tgccgtcggg tgtccgtgat tttcgtatga
    57421 tgagaaggtc tgtagtcgat gccattttaa gcttgaccga gtccaatcgt ttttcaaagg
    57481 ggctcttcgc ctgggtgggt ttcaaaacct actatttgga ctatccaaat gtcgaaaggc
    57541 aggctggcaa gaccagttgg agttttaggc aactcttttt ttactccatt gaagggattg
    57601 ttaatttttc agatttccct ttgactatag cctttgtagc tggtctccta tcttgttttc
    57661 tttctctgct gatgaccttt tttgttgtgg ttcggaccct cattttgggc aatccgacat
    57721 ctggttggac ctctctgatg gctgttattc tctttcttgg aggcattcaa ctcttgacca
    57781 ttgggattct cggtaagtat atcagtaaga tttatttaga gactaaaaaa agaccacttt
    57841 atcttatcaa agaaaaaagt gaccttcctg attttacaga aaaaataaag tgaaaagact
    57901 ataattttac atggaaatgt gctaaactag agggagtgga ttatcgccat tgatttaggc
    57961 ttcctggttt ccaatcaggg cgcgagttgg gcaattttta acagcctcta agacatcctg
    58021 actaggagaa atttcttttt ccagttggtc agggtcatcg taaaaacgca cgattccatt
    58081 atcgtggtaa tcaaataaat cagaataagt ttggcaaagt ccacaggcga tacatcgttc
    58141 aggtataagt gtgattttca tgttcatatt tatattgtaa taagaaaagt aaaaaaaaac
    58201 aaggagtaag gtatggcaaa agaaccgtgg caagaagata tttatgatca agaagaatca
    58261 agagcagggc gtcggcatcg aaaccacgga ggggctgata ggatggctaa tcgtattttg
    58321 acgatcctag ctagtatttt ctttgtaatt gtggtggtga tggtcatcgt tctcatctat
    58381 ctatcatcgg gggggagtaa tcgcacagca gccttaaaag actttcatga ttctgatgca
    58441 agtgtagtac aaatctcatc ttcaagcagt tctcagcctg agcagagttc agagccagaa
    58501 tctacttcta gtagttcaga agaagctgct aatcctgaag gaacgattaa agttctcgca
    58561 ggagaagggg aagcagctat tgccgctcgt gcaggaatct ccattgctca gttagaggcc
    58621 ttgaatcctg ggcacatggc tacaggatct tggtttgcta atccaggtga tgttataaaa
    58681 ataaaatagg agccgatatg aaaacaattc aaattgctat tgatggtcct gcttccagcg
    58741 gtaagagtac ggtcgcaaag attattgcta aggattttgg gttcacctac cttgatacag
    58801 gagctatgta tcgtgcagcg acctatatgg ctcttaagaa ccaattagga gttgaagaag
    58861 tcgaagacct tctagccttg ttggaccagc atccaatcag ctttggacgt tcagaaactg
    58921 gagaccagct tgtttttgta ggagatgtgg atattaccca tcctatccgt gaaaatgaag
    58981 tgaccaatca tgtttctgct attgcagcaa ttcctgaagt gcgtgagaaa ctggtttctc
    59041 tccaacaaga aattgcccag caaggcggga ttgtcatgga tggtcgcgat attggaactg
    59101 ttgtattgcc acaagcagaa ttgaaaattt tcctagtagc ttctgttgat gagagagcag
    59161 agcgtcgtta caaggaaaat attgccaagg gaattgaaac agaccttgaa accctaaaaa
    59221 aggaaattgc tgcgcgtgac tacaaggata gtcatcgtga gacttctcct ctcaaacaag
    59281 cagaggatgc tgtctacctt gatacaactg gtttgaacat tcaagaagta gttgaaaaaa
    59341 tcaaagcaga agctgaaaaa agaatgtaaa tgtagaaaag ccgatagatt gatatcggtt
    59401 tttttctaaa tttgtcaaaa tgctgatttt agggtataat agttgctgtt cgagaaattt
    59461 tgattttcaa agaatagtga atgatgataa ggagaaacca tgaacaattt accaaattgt
    59521 ccaaaatgta actcagagta tgtctacgaa gacggtgccc tactggtttg cccagagtgt
    59581 gctcatgagt ggaatcctgc tgaagttgca gaagtagaag aaggtcttgt cgctatcgat
    59641 gccaacggaa ataaattgac tgatggtgat acagtaactc tcatcaagga cttgaaagta
    59701 aaaggtgcgc caaaagattt gaaacaaggg acgcgcgtga aaaatatccg catcgtagaa
    59761 ggcgatcaca atatcgactg taagattgat ggttttggtg ccatgaaact taaatcagag
    59821 tttgtgagga agatttaagc atgtcaaaac actataaact tgtattttat agccgtatct
    59881 tcttgtttct agcggctttt acgggagttt atcttgaaat tactaggcat ggtggttttg
    59941 ggatgcttct ctattacacg gttctgtcca acctcttggt aactattttt accctttatc
    60001 ttctaaaggt tatgagccgt gtaggtgaaa attggcaaag gccaagtctc ttgcgcttaa
    60061 aaggtggggt caccatgagt atcatgatta cctgtgtgat ttaccatttc ctcttggcgc
    60121 ccattgcgac taatttctat accctagaaa atttcctttg ccactatatc gttcccatct
    60181 ggtttttagc ggataccctc ttttttgaca aacagggtca atacaagatt tgggatccag
    60241 cagtgtggac cattttaccc tttctgtata tgatgtttgc tctttttaat ggcttggttc
    60301 taaaactcaa tattccaaat gccaaggata atcctttccc ttacttcttt ttgaatgtga
    60361 acaagggttg gaatgttgtg tttaagtggt gtctgattat ctttgttgcc tatatggtag
    60421 caggatttat tttctacttt atcaagcaaa tcaagagaaa gtcatcctaa tactcttcga
    60481 aaatctcttc aaaccacgtt agtttccatc tgcaacctca aaacactgtt ttgaacaacc
    60541 tgcggctagc tttctagttt gctctttgat tttcattgag tatgagatac aagggattca
    60601 ttttcgaatt taagaaggag tctacaaacc aatgaggctt cttcttttct tgcttatttg
    60661 ataactatca aaaaagtaga agattaagag aaatatagaa agagatttca tgaaacaatt
    60721 tttagaacgg gccagcattt tggctctctc cctcgttttg attacctcct tttccatttc
    60781 gagtgcccta ccagccatgt ttgactatta tcagggttat tctaaggaac aaattgagct
    60841 cttggtgagc ttgccttcct ttggaatcat gatgatgtta ctgctaaatg gtttcttaga
    60901 aaaaatattt cctgagcgct tacagattag tttgggcttg ctgattttat cattgagcgg
    60961 tacagctccc ttctggtacc aagcctatcc ctttgtcttt ggaacacggc ttctctttgg
    61021 tttgggtctt gggatgatca atgccaaggc catttctatt atcagtgaac gctaccaagg
    61081 aaaaaggcga attcagatgt tagggctacg cgcttctgca gaggtcgttg gagcttctct
    61141 cattaccttg gccgtcggtc agttgttggc ctttggttgg acagctatct ttctagccta
    61201 tagtgctgga tttttggtga tgccccttta tctgctcttt gtcccttatg gaaaatcaaa
    61261 gaaagaagtc aagaaaagag cgaaggaagc aagtcgttta actcgagaaa tgaaaggctt
    61321 gatttttacc ttagctatcg aagcggcagt tgtagtttgt accaatacag ctattaccat
    61381 ccgtattcca agtttgatgg tggaaagagg attgggggat gcccagttat ctagttttgt
    61441 tcttagtatc atgcagttga tcgggattgt ggctggggtg agtttttctt tcttgatttc
    61501 tatctttaaa gagaaactgc tcctctggtc tggtattacc tttggcttgg ggcaaatcgt
    61561 gattgccttg tcttcatcct tgtgggtggt agtagcagga agtgttctgg ctggatttgc
    61621 ctatagtgta gtcttgacga cggtctttca acttgtctct gaacgaattc cagctaaact
    61681 cctcaatcaa gcaacttcat ttgctgtatt aggctgtagt ttcggagcct ttacgacccc
    61741 atttgttcta ggtgcaattg gcttactaac tcacaatggg atgttggtct ttagtatctt
    61801 aggaggttgg ttgattgtaa tctctatctt tgtcatgtac ctacttcaga agagagctta
    61861 ggattgattc ctaagttttt cttttgatac tcaatgaaaa tcaaagagca tagttgattg
    61921 agtttggaat agtacgctgt agctgctaaa atatttctag aaattaattt gacttttcta
    61981 atagagttat tcatatctta tttcaatcta ctatagaaag ctagccgcag gttgctcaaa
    62041 atagtgtttt gaggttgcag atggaaactg acgtggtttg aagagatttt cgaagagtat
    62101 gagattttta tacccataca atatttgttt taggtccttg tttacagact aatttcttga
    62161 taaaatagag gttatgacga gatataaagc aactatttcc tatgatggtt atgcctttgc
    62221 tggctttcag cgccagtctc atgcgcgtag cgttcaggaa gaaattgaaa aaaccttgac
    62281 cagattaaat aaagggcaaa ccattactgt tcacggtgct ggtaggacag atagtggggt
    62341 tcatgccctg ggacaggtca ttcattttga cctgccttat cagatggatg aggagaaact
    62401 ccgttttgcc ttggataccc agtctcctga agatattgat gtgatttcga ttgagcttgt
    62461 ggcagatgat tttcattgcc gttatgccaa acatagcaag acctatgagt ttattgtgga
    62521 tagaggacgt cccaaaaatc ctatgcgccg tcactatgcc acccactttc cctacccact
    62581 cgatgtggaa cgaatgcaga ttgcaatcaa aaagctagag ggaacccatg attttaccgg
    62641 ttttacagcc tctgggacta gtgtagagga taaggttcgc accatcacag aagctagttt
    62701 aatagtcgat gagacaggac aatttttgac ctttaccttt tcaggaaatg gtttcttgta
    62761 taaacagatt cgcaatatgg tggggactct tctcaaaatc ggtaacaacc gcatgccagt
    62821 agagcagatt gatctcatct tggagaagaa ggacaggcaa cttgcaggtc ccactgcagc
    62881 accaaatggt ttgtatttaa aggagattcg ttatgaagaa taatcgtatt ttagcacttt
    62941 ctggaaatga tatttttagt ggtggtggac tgtcagctga tttggctacc tataccttga
    63001 acggcttgca tgggtttgta gcagtgactt gtttgacagc cttgacagaa aaaggatttg
    63061 aagtctttcc aactgatgat accatttttc aacatgaatt agatagctta cgtgatgtgg
    63121 aatttggggg aattaagatt ggtcttctcc ctactgtcag tgtggctgag aaggccttgg
    63181 actttatcaa acaacgccca ggagtacctg tggtgttgga tcctgtcttg gtctgcaagg
    63241 aaacgcatga tgtagctgtc agtgagctct gccaagagtt gattcgcttt ttcccttatg
    63301 tcagtgtgat tacgcctaat ctcccagaag cagaattatt atccggtcag gaaattaaaa
    63361 ccttggaaga catgaaaact gcagcgcaga aattgcatga tttaggagcg ccagcagtca
    63421 ttatcaaggg aggcaatcgt cttagtcagg acaaggctgt ggatgtcttt tatgatggac
    63481 agacctttac tatcctagaa aatccagtta tccaaggcca aaatgctggt gcaggttgta
    63541 cctttgcctc tagcattgcc agtcacttga ttaaaggtga taaacttttg ccagcagtag
    63601 aaagctctaa ggctttcgtt tatcgtgcta ttgcacaagc agatcagtat ggagtaagac
    63661 aatatgaagc aaacaaaaac aactaaaatc gcccttgtat ccctattaac cgccctttct
    63721 gtggttctag gttatttctt aaaaatccca acacctacag gaattctaac tcttttagat
    63781 gctggtgtct tctttgcggc cttttacttt ggtagtcgtg aaggagcggt agtcggagga
    63841 ctagcaagtt tcttgattga cctcttatca ggctaccctc agtggatgtt ctttagcttg
    63901 gtcaaccatg gcttgcaggg atttttcgca ggatttaaag gaaaaagtca gtggttaggc
    63961 cttattttag caactattgc catggtagga ggctacgcct tgggttctac tttgatgaat
    64021 ggctgggcag cagccctccc agaaattcta ccaaatttca tgcaaaatat ggtagggatg
    64081 attgtaggat ttattcttag tcaaagtatc aagaagatta agtaatactc ttcgaaaatc
    64141 tcttcaaacc acgtcagctt ccatctgcaa cctcaaaaca ctgttttgag cagcctgagg
    64201 ctagctttct agtttgcact ttgattttca ttgagtataa agaggttgag taaaaagtat
    64261 ttcaaataag aaaaacgcat agtatcaggt gttgaatgaa ctgcccccca aaagttagac
    64321 agaaaaaatc taacttttgg ggtgttttat tatgaaacta acttatgatg ataaagttca
    64381 gatctatgaa cttagaaaac aaggatatag cttagagaag ctttcaaata aatttgggat
    64441 aaacaattct aatcttaggt acatgattaa attgattgat cgttacggaa tagagttcgt
    64501 caaaaaaggg aaaaatcgtt actattctcc tgatttaaaa caagaaatga ttcataaagt
    64561 ctgacatgaa ggctagacta aagatagagt ttctcttgaa tacggtctcc caagtcgtac
    64621 gatacttctt aactggctag cacaatacag gaaaaacggg tatactattg ttgagaaaac
    64681 aagagggaga gtacctaaaa tgggacgt
//
LOCUS       DBERCW010000007        63405 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.007, whole genome shotgun sequence.
ACCESSION   DBERCW010000007 DBERCW010000000
VERSION     DBERCW010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 63405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.007"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..305)
                     /locus_tag="ACL72M_000589"
                     /pseudo
     CDS             complement(1..305)
                     /locus_tag="ACL72M_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389597.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            474..1016
                     /locus_tag="ACL72M_000590"
     CDS             474..1016
                     /locus_tag="ACL72M_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGS0715764.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            1016..1645
                     /gene="nth"
                     /locus_tag="ACL72M_000591"
     CDS             1016..1645
                     /gene="nth"
                     /locus_tag="ACL72M_000591"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGS0715765.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            1856..2377
                     /gene="pyrR"
                     /locus_tag="ACL72M_000592"
     CDS             1856..2377
                     /gene="pyrR"
                     /locus_tag="ACL72M_000592"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGS0715766.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            2396..3319
                     /locus_tag="ACL72M_000593"
     CDS             2396..3319
                     /locus_tag="ACL72M_000593"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGS0715767.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            3369..4448
                     /locus_tag="ACL72M_000594"
     CDS             3369..4448
                     /locus_tag="ACL72M_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGS0715768.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            4760..7936
                     /gene="carB"
                     /locus_tag="ACL72M_000595"
     CDS             4760..7936
                     /gene="carB"
                     /locus_tag="ACL72M_000595"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGS0715769.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(8211..9020)
                     /locus_tag="ACL72M_000596"
     CDS             complement(8211..9020)
                     /locus_tag="ACL72M_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0715770.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9022..9825)
                     /locus_tag="ACL72M_000597"
     CDS             complement(9022..9825)
                     /locus_tag="ACL72M_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0715771.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(9835..11322)
                     /gene="tacF"
                     /locus_tag="ACL72M_000598"
     CDS             complement(9835..11322)
                     /gene="tacF"
                     /locus_tag="ACL72M_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGS0715772.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            11658..12365
                     /locus_tag="ACL72M_000599"
     CDS             11658..12365
                     /locus_tag="ACL72M_000599"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGS0715773.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            12370..13392
                     /locus_tag="ACL72M_000600"
     CDS             12370..13392
                     /locus_tag="ACL72M_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGS0715774.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            13409..14278
                     /gene="licA"
                     /locus_tag="ACL72M_000601"
     CDS             13409..14278
                     /gene="licA"
                     /locus_tag="ACL72M_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGS0715775.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            14268..15146
                     /locus_tag="ACL72M_000602"
     CDS             14268..15146
                     /locus_tag="ACL72M_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0715776.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            15158..15847
                     /locus_tag="ACL72M_000603"
     CDS             15158..15847
                     /locus_tag="ACL72M_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGS0715777.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            15943..16791
                     /gene="dprA"
                     /locus_tag="ACL72M_000604"
     CDS             15943..16791
                     /gene="dprA"
                     /locus_tag="ACL72M_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGS0715778.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            17680..18723
                     /locus_tag="ACL72M_000605"
     CDS             17680..18723
                     /locus_tag="ACL72M_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGS0715779.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            18890..20977
                     /gene="topA"
                     /locus_tag="ACL72M_000606"
     CDS             18890..20977
                     /gene="topA"
                     /locus_tag="ACL72M_000606"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGS0715780.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            21083..21442
                     /locus_tag="ACL72M_000607"
     CDS             21083..21442
                     /locus_tag="ACL72M_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGS0715781.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            21535..22167
                     /locus_tag="ACL72M_000608"
     CDS             21535..22167
                     /locus_tag="ACL72M_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGS0715782.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            22211..22867
                     /locus_tag="ACL72M_000609"
     CDS             22211..22867
                     /locus_tag="ACL72M_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGS0715783.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            22937..23980
                     /locus_tag="ACL72M_000610"
                     /pseudo
     CDS             22937..23980
                     /locus_tag="ACL72M_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            23992..25029
                     /gene="leuB"
                     /locus_tag="ACL72M_000611"
                     /pseudo
     CDS             23992..25029
                     /gene="leuB"
                     /locus_tag="ACL72M_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            25026..25295
                     /locus_tag="ACL72M_000612"
     CDS             25026..25295
                     /locus_tag="ACL72M_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGS0715784.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            25299..25658
                     /gene="leuD"
                     /locus_tag="ACL72M_000613"
     CDS             25299..25658
                     /gene="leuD"
                     /locus_tag="ACL72M_000613"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGS0715785.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            25820..26443
                     /locus_tag="ACL72M_000614"
                     /pseudo
     CDS             25820..26443
                     /locus_tag="ACL72M_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            26609..28540
                     /locus_tag="ACL72M_000615"
     CDS             26609..28540
                     /locus_tag="ACL72M_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGS0715786.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSINSRQNLSVNYDSGVSGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            28527..29843
                     /locus_tag="ACL72M_000616"
     CDS             28527..29843
                     /locus_tag="ACL72M_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGS0715787.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFFHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            30018..31004
                     /locus_tag="ACL72M_000617"
     CDS             30018..31004
                     /locus_tag="ACL72M_000617"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGS0715788.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCVKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            31068..31139
                     /locus_tag="ACL72M_000618"
     tRNA            31068..31139
                     /locus_tag="ACL72M_000618"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31101..31103,aa:Arg,seq:ccg)
     gene            31322..32020
                     /gene="rnc"
                     /locus_tag="ACL72M_000619"
     CDS             31322..32020
                     /gene="rnc"
                     /locus_tag="ACL72M_000619"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGS0715789.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            32011..35550
                     /gene="smc"
                     /locus_tag="ACL72M_000620"
     CDS             32011..35550
                     /gene="smc"
                     /locus_tag="ACL72M_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGS0715790.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSHQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            35547..36341
                     /locus_tag="ACL72M_000621"
     CDS             35547..36341
                     /locus_tag="ACL72M_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0715791.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            36341..37159
                     /locus_tag="ACL72M_000622"
     CDS             36341..37159
                     /locus_tag="ACL72M_000622"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0715792.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            37163..38440
                     /gene="ftsY"
                     /locus_tag="ACL72M_000623"
     CDS             37163..38440
                     /gene="ftsY"
                     /locus_tag="ACL72M_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGS0715793.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(38486..39973)
                     /gene="zwf"
                     /locus_tag="ACL72M_000624"
     CDS             complement(38486..39973)
                     /gene="zwf"
                     /locus_tag="ACL72M_000624"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGS0715794.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWD
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(40122..40862)
                     /locus_tag="ACL72M_000625"
     CDS             complement(40122..40862)
                     /locus_tag="ACL72M_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0715795.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(40862..43027)
                     /locus_tag="ACL72M_000626"
     CDS             complement(40862..43027)
                     /locus_tag="ACL72M_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS0715796.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            43200..44153
                     /locus_tag="ACL72M_000627"
     CDS             43200..44153
                     /locus_tag="ACL72M_000627"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGS0715797.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLQQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSSLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            44230..46218
                     /gene="uvrB"
                     /locus_tag="ACL72M_000628"
     CDS             44230..46218
                     /gene="uvrB"
                     /locus_tag="ACL72M_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGS0715798.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            46228..46791
                     /locus_tag="ACL72M_000629"
     CDS             46228..46791
                     /locus_tag="ACL72M_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS0715799.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            46757..47245
                     /locus_tag="ACL72M_000630"
     CDS             46757..47245
                     /locus_tag="ACL72M_000630"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0715800.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            47319..47786
                     /locus_tag="ACL72M_000631"
     CDS             47319..47786
                     /locus_tag="ACL72M_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS0715801.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGSLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(47783..48298)
                     /locus_tag="ACL72M_000632"
     CDS             complement(47783..48298)
                     /locus_tag="ACL72M_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGS0715802.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(48310..48837)
                     /locus_tag="ACL72M_000633"
     CDS             complement(48310..48837)
                     /locus_tag="ACL72M_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0715803.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(49115..49678)
                     /locus_tag="ACL72M_000634"
     CDS             complement(49115..49678)
                     /locus_tag="ACL72M_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0715804.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(49662..50213)
                     /gene="coaC"
                     /locus_tag="ACL72M_000635"
     CDS             complement(49662..50213)
                     /gene="coaC"
                     /locus_tag="ACL72M_000635"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGS0715805.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(50225..50914)
                     /gene="coaB"
                     /locus_tag="ACL72M_000636"
     CDS             complement(50225..50914)
                     /gene="coaB"
                     /locus_tag="ACL72M_000636"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGS0715806.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            51144..52814
                     /locus_tag="ACL72M_000637"
     CDS             51144..52814
                     /locus_tag="ACL72M_000637"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGS0715807.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIYVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            53142..54317
                     /gene="mutY"
                     /locus_tag="ACL72M_000638"
     CDS             53142..54317
                     /gene="mutY"
                     /locus_tag="ACL72M_000638"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGS0715808.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            54372..55076
                     /gene="yycF"
                     /locus_tag="ACL72M_000639"
     CDS             54372..55076
                     /gene="yycF"
                     /locus_tag="ACL72M_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGS0715809.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            55069..56418
                     /gene="vicK"
                     /locus_tag="ACL72M_000640"
     CDS             55069..56418
                     /gene="vicK"
                     /locus_tag="ACL72M_000640"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGS0715810.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            56420..57229
                     /locus_tag="ACL72M_000641"
     CDS             56420..57229
                     /locus_tag="ACL72M_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS0715811.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            57320..57562
                     /gene="relB"
                     /locus_tag="ACL72M_000642"
     CDS             57320..57562
                     /gene="relB"
                     /locus_tag="ACL72M_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGS0715812.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            57564..57818
                     /locus_tag="ACL72M_000643"
     CDS             57564..57818
                     /locus_tag="ACL72M_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGS0715813.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            57865..58608
                     /locus_tag="ACL72M_000644"
                     /pseudo
     CDS             57865..58608
                     /locus_tag="ACL72M_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(58909..59895)
                     /locus_tag="ACL72M_000645"
     CDS             complement(58909..59895)
                     /locus_tag="ACL72M_000645"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGS0715814.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            60089..62557
                     /gene="gyrA"
                     /locus_tag="ACL72M_000646"
     CDS             60089..62557
                     /gene="gyrA"
                     /locus_tag="ACL72M_000646"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGS0715815.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            62557..63300
                     /gene="srtA"
                     /locus_tag="ACL72M_000647"
     CDS             62557..63300
                     /gene="srtA"
                     /locus_tag="ACL72M_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGS0715816.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT        19516 a        11279 c        13888 g        18722 t
ORIGIN      
        1 aacaggtcca tagagactta gtacgtgttt gacatactcg taatggattt tatcatagtt
       61 tcgccaagca gtgcgtgctt gattgtttag ttttaggcta cccagtccaa tcagaggact
      121 ggtgggttgg taaaatttct caagattaat taagatactg ttgttcaact tttctgtttt
      181 ttgagctctt gcatagtagt gtttagcagc tcttgtagtc gaatatcatc tgccgtaacc
      241 tgtttacagt tttggtagct tttatttaac ttggatagga gttgaatgag tttcttgtct
      301 tccatgtgag catcctcctt gatctgatgt actctttccc tatagtatag cactaaaaaa
      361 taaaactatc atagtaaata tgttaaaatt tgaattttaa ttacaaagtt tggtgtgctg
      421 atttgtagcc ttttcatggt ataatcaaga gagtaaatct ttatggagga agtatgaaat
      481 taaatattca agaaattcgt aagcagtctg aaggtttgaa ctttgaacaa acgttagatt
      541 tagttgatga cctgcgtgca cgtaatcaag aaattttaga tgtaaaagat atccttgcag
      601 ttgggaaagt acaatatgaa gaccgtatgt atttcttaga ttatcaacta tcttatacca
      661 ttgttcttgc ttcgagtcgc agtatggagc cagttgagtt agttgaatct tatccagtca
      721 cggaagtttt catggaaggc gcaactaacc agctagatca agaagtttta gatgatgact
      781 tggtcttgcc catcgaaaat ggggcgcttg accttgctga gagtgtatca gacaatatcc
      841 tgctaaacat tcctatcaag gtcttgacgg ctgaagaaga agctggtcaa ggatttgtct
      901 caggaaatga ctggcaaatc atgacagagg aagaatacca agctcaacaa gcagtaaaga
      961 aagaagaaaa cagtcctttt gctggcttac aaggactatt tgacggagat gaataatggt
     1021 cttgtcaaaa aaacgagcac gaaaggtgct agaagaaatc attgccctct tcccagatgc
     1081 caagcctagt cttgatttta ccaatcattt tgaactcctg gttgcggtca tgttatcagc
     1141 ccagacgaca gatgcagcgg taaataaggc cacaccaggt ctctttgttg cctttccaac
     1201 accccaagct atgtctgtag cgacagagag tgagattgct tcacatattt ctcgcttggg
     1261 attgtatcgg aataaagcta aattccttaa aaaatgtgcc caacagttac tagacgattt
     1321 tgatggtcaa gtccctcaga cacgtgaaga attggagagt ttggcaggtg ttggtcgcaa
     1381 gacagccaat gttgtcatga gtgtaggatt tgggattcca gcctttgcag tggatactca
     1441 tgtggagcgt atttgcaaac accacgatat tgtcaaaaaa tcagcgacgc cacttgaggt
     1501 ggaaaagcgg gtcatggata tcttgccgcc tgagcagtgg ttagctgccc atcaggccat
     1561 gatttatttt ggaagagcca tttgccatcc aaaaaatcca gagtgtgacc agtacccaca
     1621 attatatgat tttagcaatt tgtaagatgc tacattgaaa ctttttgctt gattttaagc
     1681 atgctttgtg ctatagtaaa tgataactaa atattccttt aaacctgtcc cgtgaggcag
     1741 gcaaggagcg cgataaagta gaagggtgaa gtctacactg tgtgcagtag ggctcgcttg
     1801 gctataaatt tcaagtctcc ttgtttaagg agacttttct ttttggaggt ttgtcatgaa
     1861 aacaaaagaa gttgtagacg aattgaccgt caaacgagcg attacgcgta ttacttatga
     1921 gattatcgaa cgcaacaaag atttgaataa gatcgtcttg gctggtatta aaactcgtgg
     1981 tgtctttatt gcccaccgaa tccaagaacg tttgaagcag ttagaaaatc tttcagttcc
     2041 tgttgtggaa ttggatacta aacctttccg tgatgatgtt aaaagtggag aagatacttc
     2101 tttggtttct gtcgatgtga cagaccgcga agttatcttg gtggatgatg tgctctatac
     2161 aggtcgtacc atccgtgctg ctattgataa tattgtcggt catggtcgtc ctgcgcgtgt
     2221 gagtttagca gttctagtcg atcgtggaca tagagaattg ccaatccgtc cagattacgt
     2281 tggaaaaaat atcccaacca gtcgttctga agaaatcatc gtagagatga cagaacttga
     2341 tgaccaagac agagttctga ttactgaaga agcttagaaa gttaaaggag tagccatgtc
     2401 agaaaatcaa caagcattga accatgtggt gtccatggaa gacctcactg tcgatcaagt
     2461 aatgaaattg atcaagcgag gaattgagtt taaaaatgga gcccagcttc cctatgaaga
     2521 ccatccgatt gtttccaatc tcttctttga ggattctaca cggacacata agtcctttga
     2581 agtcgcagag attaaacttg gattggaacg acttgacttt gatgtgaaga ctagttcggt
     2641 taataagggt gagacacttt atgacaccat tttgactctg tctgctttag gagtggatgt
     2701 ctgtgtgatt cgccatccag aggtcgacta ctatagagaa ttgattgcta gtccaacgat
     2761 tacgacttcc atcatcaatg gtggagatgg ttcgggccaa caccctagcc agagcttgct
     2821 tgatttgatg accatttatg aggaatttgg ccactttgag ggtcttaaag ttgctattgc
     2881 aggtgacttg gatcactcac gcgttgccaa atccaatatg cagattttga aacgcttggg
     2941 agctgaactc tttttcgctg gacctgagga atggagaagt caagagtttg cagactatgg
     3001 acagtttgta accattgatg aaatcattga tcaggttgat gtcatgatgt ttctccgtgt
     3061 gcaacacgaa cgccatgata gtggagctgt attttcaaaa gaagactacc atgcccaaca
     3121 tggcttgact caagaacgtt acgatcgttt gaaagaaaca gcaatcctca tgcacccagc
     3181 tccaatcaat cgtgatgtag aaatagcaga ccacttggtt gaagcaccaa aatcacggat
     3241 tgtccaacaa atgaccaatg gtgtctttgt tcgaatggca atcttagaat ccgtactagc
     3301 gagtagaaac gccaactaaa acacaagacg ttaaaagacg ccagtgagcg tccacgagag
     3361 gtgaaaatat gacaaaaaga attctagtat tagaagatgg cacagttttt gaaggcaagg
     3421 ccttcggagc agatattgat gtaacaggcg aaatcgtctt taatacaggg atgaccggct
     3481 accaagaatc cattacagac cagtcttata atggacaaat cttgaccttt acttatcctt
     3541 tggtaggaaa ttatggtatt aatcgtgatg attatgaatc cattattcca acttgtaagg
     3601 gagtcgttgt ttttgaagaa gcgcgtagag ctagcaactg gcgcaaccaa atgaccttgg
     3661 atgaattttt gaaagccaag aaaattccag ggatttcagg aattgatacg cgtgctctta
     3721 ccaagattat ccgtaagcat ggtactatgc gtgcaacctt gacccatgtt ggggacagta
     3781 tggaccatgt gacggaccag ctccaagcaa cagttttacc gacagacaat atcaaacagg
     3841 tttctactaa aacgtcttat ccagctccag gagttggttt gagcgtggtg ctagtggact
     3901 ttggtctcaa gcactcaatc ctacgtgaac tttctaaacg caactgtaac gtgacagttg
     3961 ttccttattc gacaacggct gaagaaattc tccatctcaa tcctgatgga gttatgttgt
     4021 caaatggtcc aggtaaccca gaagacgttc cacaagcact cgacatgatt cgcggtgtac
     4081 aaggaaaaat tccaatcttt ggtatttgta tgggacacca actctttgca atggcaaacg
     4141 gggctaagac ctataagatg aagtttggcc atcgtggatt caaccatgcg gtacgtgaaa
     4201 tcgcaacagg acgagtagac ttcaccagcc agaaccatgg ttatgcagtc agccgcgagg
     4261 atttgccaga gcacttgatt attacccacg aagaaatcaa tgacaagtca gtggaaggtg
     4321 tgcgccacag ataccaacct gctttctctg ttcaatacca cccagatgca gctcctgggc
     4381 cacacgacgc tagctaccta tttgacgagt ttatcgagat gatggaagtt tttaaacaat
     4441 caaactaaga acgagtaaaa gctcgtcgga gaatttatgt aactgaacac ggacggaaag
     4501 ctcagaattt agagaaacca acttggattg tcaatccttc cttgatttct taaaattcaa
     4561 tcgctttcta ttcgtccttt gtatcttatt taatgtcgcc ctgagaggcg acgaatagaa
     4621 aggagaagat acattgttcg cggaagtgaa cacgccctaa gaactgtgtg aaaaagataa
     4681 acatcgtctt gacgctgaag gcgtctgcgc cgagtttcct attttcactg tgttctttac
     4741 gggctttgta tcataaacta tgcctaaacg tactgatatt caaaaaatta tggtgattgg
     4801 ttctggtccg attattattg gtcaggctgc tgagtttgac tacgctggga cccaggcttg
     4861 cttgtcgttg aaagaggaag gttatgaggt tgttttggtt aactcaaatc ctgcaaccat
     4921 catgacggac aaggaaattg ctgacaaggt ttacattgaa ccgattacac ttgagtttgt
     4981 gacacgtatt cttcgtaagg aacgtccaga tgccttgcta ccaacactcg gtggtcagac
     5041 aggtctcaac atggccatgg aattatctaa aaatggtatc ctagacgagc ttggcgttga
     5101 acttctgggt accaaattat ctgccattga ccaagcggag gaccgtgacc tctttaaaca
     5161 attgatggaa gagcttgagc aacccattcc agaatctgaa attgttaaca cagtagaaga
     5221 agcagttgcc tttgcagcga caattggcta cccagtcatc gttcgtccag cctttaccct
     5281 tggtggtact ggtggtggta tgtgtgccaa cgaaaaagaa ttgcgtgaaa tcactgaaaa
     5341 tggtttgaaa ttgtcacctg ttacccaatg tttgattgag cgttcgattg ccggttttaa
     5401 ggaaattgaa tacgaagtga tgcgtgactc agctgacaat gccttggttg tttgtaacat
     5461 ggaaaacttt gacccagttg ggattcacac aggggattcc attgtatttg cccctgcgca
     5521 aaccatgtca gactatgaaa accaaatgct tcgtgatgcg agcttgagca ttattcgcgc
     5581 cctcaagatt gaaggtggat gtaatgttca gctagctctt gatcctaaca gcttcaagta
     5641 ttatgttatc gaagtaaacc ctcgtgtatc acgttcgtca gcccttgctt ctaaagcgac
     5701 aggatatccg attgctaagt tggctgccaa gattgcagta ggtttgacct tggatgaggt
     5761 tataaaccca gttacaggtt caacctatgc catgtttgaa ccagcccttg actacgtagt
     5821 tgctaagatt ccacgtttcc catttgacaa gtttgaaaag ggtgaacgcc gtctcggtac
     5881 acaaatgaag gcgactggag aagtcatggc aatcggtcgt aacatcgagg aatctcttct
     5941 caaggcctgc cgctcccttg aaattggggt gcaccacaat gaaatacctg aacttgcagc
     6001 agtttctgat gatgccttga ttgaaaaggt tgtcaaagcc caagatgacc gtctcttcta
     6061 cgtatcagaa gccattcgtc gtggctacac acctgaagaa attgcagagc ttacaaaaat
     6121 tgatatcttc tatcttgata aactcttgca tatctttgaa attgagcaag aattgggtgc
     6181 tcatccacaa gatctagaag ttttgaaaac agccaaactt aatggtttct cagaccgtaa
     6241 gattgctgaa ctctggggaa cgactgatga tcaagttcgc caacttcgct tggaaaacaa
     6301 gattgttcca gtttataaga tggtagatac ttgtgcggca gagttcgact ctgaaacgcc
     6361 atatttctat tcaacctatg gttgggaaaa tgaatctatc agatctgata aagaatctgt
     6421 acttgtccta ggttcaggtc caatccgtat cggtcaaggg gttgagtttg actacgcaac
     6481 cgttcactct gttaaggcta tccaggcagc tggttatgaa gctatcatca tgaactcaaa
     6541 cccagagacc gtttcaacag acttctctgt atcagataag ctttactttg agccattgac
     6601 attcgaagat gttatgaacg tcattgactt ggaacaacca aagggagtta tcgttcagtt
     6661 tggtggtcaa acagccatca accttgcgga gccattggca aaagcaggtg tgaccatcct
     6721 tggtacacag gttgctgacc tagaccgtgc cgaagaccgt gacctcttcg agcaagctct
     6781 caaagaattg gatattccac agccaccagg acaaacggct accaatgaag aagaagcagc
     6841 tcttgcagct cgtaagattg gcttcccagt tcttgtccgc ccatcttatg tacttggtgg
     6901 acgtgccatg gaaatcgttg aaaacgaaga agaccttcgt tcttacatgc gaactgctgt
     6961 taaggctagt ccagatcacc cagttcttgt cgactcttat atcgttgggc aagagtgcga
     7021 agttgatgcc atttcagatg gtaaagatgt gctcattcct ggtatcatgg agcatatcga
     7081 acgtgctggt gtccactcag gtgactcaat ggctgtttac ccaccacaaa ccttgtcgca
     7141 aaaggttcag gagaccatcg cagactacac caaacgctta gcaatcggtc ttcactgcct
     7201 tggaatgatg aacatccagt ttgttatcaa ggatgaaaaa gtctacgtta ttgaggtcaa
     7261 tccacgtgcc agccgtactg ttccattcct atctaaggta accaatattc ctatggctca
     7321 agtagcgacc aagctcattc ttggtcaaag tttatcagaa cttggctacc aaaatggact
     7381 ttaccctgaa agcacccgtg ttcatatcaa ggcacctgtc ttctccttta ccaaactagc
     7441 taaggtagac agcttgctcg gtcctgaaat gaagtcaaca ggtgaagtta tgggttctga
     7501 tgctactttg gaaaaagctc tctataaagc ctttgaagct tcttatctac acttgccaac
     7561 ttttggtaat gtcgtcttta ccatcgctga tgatgccaaa gaagaagcct tgaacttggc
     7621 tcgtcgtttc caaaacattg gttatggaat ccttgcgaca gaagggacag cagccttctt
     7681 tgctagtcat ggcttgcaag cccaacctgt tggtaagatt ggtgatgacg ataaggatat
     7741 cccaagtttt gtacgcaaag gaagaattca agctatcatt aacacagtag gaacaaaacg
     7801 aactgctgac gaagatggtg agcaaattcg tcgttcagcc attgaacacg gggtgcccct
     7861 cttcacagcg ctagatacag ctaatgccat gcttaaggta cttgaaagtc gtagctttgt
     7921 tacagaagcg atttaaatag aaaaataaga tatagcagac tgaatttaga acagtacaca
     7981 ggaatactaa aatatttcta taaattaatt tgaattttct aattgatttg ttcgcatctt
     8041 atttcaatct actatagaaa aaagtcttta aaattataaa acgcatcata tcaaggtttt
     8101 tcaaaaacct tgatatgatg cgttttattg tgggaatatg tatttcattt tctactaaaa
     8161 ttatgttttt gaataacctc tatcttagta gtttgtataa tccccctcaa tcagtttttg
     8221 cgataagctt taatgctatg actataccac tcttgcattt cttttgatgg tggtgtcata
     8281 taatcgccat acatctgggt taaaaattgg tcatattttt tgggaacagg caacatacgg
     8341 ccctcaaact cagttaaaat cagttcttta aaggtatcaa ctgggaagat ttctttcatc
     8401 ccttccttac cgatcccaac tcctccttca tattgaggaa tgttggttac agcatttttg
     8461 actagttgat caattttctt gtaaaagtag cgaggattga caaatcggag agcgtaccag
     8521 ctacataatc taagaaaatc ttttagtttg ctatcaccgt gaactgctcg tgattttttg
     8581 atataagcta gttgacgaag agccacatac ttatagctct tgtcgacaat gctcaagtct
     8641 gtaaatcgat caattgggaa gacatcgatg aaaaggctgg tatcatgacg cttgtactta
     8701 acatggtctt ctataacagt agaagtgtcc aaaatcgatg cgaaattatg gaagtaccaa
     8761 gaagatgtat cgtaggaaag aaccttgtag cgagggtgat tttcttcttc aataatcttc
     8821 agtaaacgct cataatcctc acgataaagg gaaatatcaa tatcatcatc ccaaggaatc
     8881 atacctttgt ggcggatggc tccaagcatg gttccataac tgagaaaata aggaatatca
     8941 tgtttcttac aagtctcatc aatatagtcc agcagggcta gttgaatttc tttaatttct
     9001 tttttttcta aatattgcat cctaatcctc caatttataa gcgtgaaatt catgactgta
     9061 gaagcgtttt tcttctggtg gtagggtcat ataatctcca taaaattgtg tcaaaatagt
     9121 atcaaatttt tcaggtgcag gaaggcttaa attctcaaag ggtaaatcga ttgttttatc
     9181 aaaggtacca cttgggaaga cttccttttc cttaaatttt gaagggataa aagccatata
     9241 ctgcccattt tcacgactat atttttgaat ttctttctcg attttatttg caaaataacg
     9301 aggagaaact ggtcgaagga gcaaccaaaa ggctgttcgt atccaatctt ttaaaaggct
     9361 atccttatag acaatatttt tatgtttact gaaagacagc agtttgaagc tttccagttt
     9421 ataacaagta tcaatgacct taggatcatc aaagcgatcc atagggaaaa tatcgataaa
     9481 gataccagac tcataggttt ttgtatttcg agtatcaata attttagtcg tactgtcggt
     9541 tatcttgata aagttgttaa agtagttctt atcagtttct aaggatagga gttcatactt
     9601 gcttttttcc ttttgaaaaa tgttaataaa tcgttggtag tcttctctag gcatggataa
     9661 atcaatatcg tcgtcccaag ggataaagcc ctcatgtcga accgccccaa tcagagtacc
     9721 gtagttaata atatagttga tattgtgctt tttacagaga gtatcaatat aatccaaaat
     9781 ttctaattca atttgtttgg catcttcaac ggttagttgt ttcattttaa actcctatga
     9841 ttttttaaat ttatttttta aggctagaac atggtttaaa aattcataga aaatgctatc
     9901 ttttgtgaag acaagtagac taatataaga gatagctgat agcaagataa tcaaaccagt
     9961 attaatcaaa aatggcaaat taatgaccat atccacagga tacacgaaat taatcaggaa
    10021 ataaattgct acaaaggaaa gtgaaaagag agagtatcga acagtatagc taaagatatg
    10081 tcccaagtgg atgagttgtt ttctatggat gaaaatgata tagaaaacaa gtagagaagc
    10141 ctctgataac atagttgtca gtaagtagta ttcgggagcc acgatacggt tgaaaaagag
    10201 gagactattc aagcccaaat tgagtagccc agcaaagact gtataaactg tgatacgttt
    10261 ttcatagcca ttggtaaaga gaatttggga accaagaatg gtatctaagg ccaggataat
    10321 cgtacgaaaa gcgaagagag aggtcaagat gccgcctccg atatattttt cactaccgta
    10381 aagtaggatg gcatttggtc ctaaaaccat gagtccaaaa ctcagtggaa tgataaagaa
    10441 gttaaagatt cgactacctc tattaaccag agaaacatag gcttctttgt ctcctttccc
    10501 cagatagtaa ctgagacgag gcacactcac tccaattgca cctgttacaa ccccagctat
    10561 aacggtcaca attcgctgag ctatggtata gtaactaacg ttgacatcaa tccctgtttt
    10621 aacgaggaag aggcgatcta aaaaagtgaa gagcatattg gcattggcaa agactaacat
    10681 ggctgtcaga gggagaaaga gtggtttaaa atcacttagg tgaatcttaa caagtttgat
    10741 gtctctttta atccaaaaat aactaatcag gtagttaatc agcgtcgata aactcatcac
    10801 aagtgtatag acaacaatat cgtgttcatt tttaacaaat aagaaaatag agaccagcat
    10861 caggatacgg atgaaggcag ttttgtaaaa gagaaaactg taattttcca gagcttcatt
    10921 gacccattcg attgaaaaaa tctgggcaat gagttgaatc cccataacaa ggtagacctt
    10981 tttgatgatt ggattatcag taaagaagag aggataggct aggatataga cagcagtggt
    11041 caaaatcgta caagcgatgc acaaataaaa aagactagaa aaggttctgt taagatcttt
    11101 tttgttatcc ttgacattac tgatagccct taaaccgtag ttatagacac cataagttgc
    11161 aaagggcaag aaaaatgaca aaatagtgtc gactgagttg aagtaaccat agtcagttcg
    11221 gtccaagaca cgcgcgacat aggttccagt taggatggga aaaataatat tcaagacacg
    11281 aattcccatg taagatagag catttaattt tatacttttc attcaattta cctcgttttt
    11341 cattatatca taaagttagc taataagaaa tgaagggcag taagccaagc aatcactttg
    11401 aagtttcaaa tcttaaattt taagttttct ttaaggaaag tatattattc tgaaggactc
    11461 taaaatttcg cagtcattta ttagtaattg ctacagaatt cctagtcatt actagaaatg
    11521 gactagtttc tttgaataat agaactgcat aattctccta ttctagaagg ggaggaccag
    11581 tatttctttt atgataggac tagattgtgg tataatagag agaataagtt tttttagtaa
    11641 gacaaaggag aaaatagatg atttatgcag gaattcttgc cggtggaact ggcacacgca
    11701 tggggatcag taacttgcca aaacaatttt tagagctagg tgatcgacct attttgattc
    11761 atacaattga aaaatttgtc ttggagccaa gtattgaaaa aattgtagtt ggtgttcatg
    11821 gagactgggt ttctcatgca gaagatcttg tagataaata tcttcctctt tataaggaac
    11881 gtatcatcat tacaaagggt ggtgctgacc gcaatacaag tattaagaaa atcattgaag
    11941 ccattgatgc ttatcgtccg cttactccag aggatatcgt tgttacccac gattctgttc
    12001 gtccatttat tacacttcgc atgattcagg acaatatcca acttgcccaa aatcatgacg
    12061 cagtggacac agtggtagaa gcagttgata ctatcgttga aagtaccaat ggtcaattta
    12121 ttacagatat tccaaatcgt gctcaccttt atcaaggaca aacacctcaa acattccgtt
    12181 gcaaggactt catggacctt tatggatctc tttctgatga agagaaggaa atcttgacag
    12241 atgcatgtaa aatctttgtg atcaaaggaa aagatgtggc cttggccaaa ggtgaatact
    12301 caaatctgaa gattacaacc gtaacagatt tgaagattgc aaaaagtatg attgagaaag
    12361 actagtaaaa tgattaatca aatttatcaa ctaactaagc ctaagtttat caatgtcaaa
    12421 tatcaggaag aggctattga ccaagagaat catatcctta tccgtcccaa ctacatggct
    12481 gtctgtcatg cggatcagcg ttactatcag ggaaaacgtg atcccaagat tttgaataaa
    12541 aagcttccaa tggcaatgat tcacgagtca tgtggaaccg tcatttctga cccgaccgga
    12601 acctacgagg ttggtcaaaa agttgtcatg attcccaatc agtctcctat gcagagtgat
    12661 gaagaattct atgaaaacta catgacaggg acccatttct tgtctagtgg atttgatggc
    12721 tttatgagag agtttgtttc tctccctaaa gatcgtgtgg tggcttatga tgctattgaa
    12781 gatacggttg cagccattac agagtttgtc agtgtgggca tgcacgctat gaatcgtcta
    12841 ttgactcttg ctcatagcaa gcgggagcgg atcgccgtta ttggagatgg aagtttagct
    12901 tttgtggttg ccaatattat caactatact ttgccagaat cagagattgt ggttattggt
    12961 cgtcattggg aaaagttgga actcttctca tttgccaaag aatgctatat tacggataat
    13021 attcctgaag agttggcctt tgaccatgct tttgaatgtt gtggtggtga tggtactgga
    13081 ccagctatta atgacttgat tcgctacatt cgtcctcagg gaacgattct catgatggga
    13141 gttagcgaat ataaagtcaa tctcaatact cgcgatgcct tagaaaaggg cttgattttg
    13201 gttgggtcat ctcgttctgg tcgcattgat tttaaaaatg ctatccaaat gatggaagtc
    13261 aagaaatttg ccaatcgtct taaaaatatc ctttatctag aagaacctgt aagagaaatt
    13321 aaagatattc atcgtgtctt tgcaaccgat ttaaacacag cctttaaaac agtgtttaag
    13381 tgggaagtat aagtactgga ggttaattgt ggagaaaatc attaaagaaa aaatttcttc
    13441 cttacttagt caagaagagg aagtcctcag tgttgaacaa ctgggtggaa tgaccaatca
    13501 aaactatttg gccaaaacaa caaataagca atacattgtt aaattctttg gtaaagggac
    13561 agaaaagctt atcaatcgac aagatgaaaa gtacaatctt gaactactaa aggatttagg
    13621 cttagatgta aaaaattatc tttttgatat tgaagctggt atcaaagtaa atgagtatat
    13681 cgaatctgcg attacgcttg attcaacgtc aatcaagacc aagttcgaca aaattgctcc
    13741 aatattacaa actattcata cgtctgctaa ggaattaaga ggagaatttg ctccttttga
    13801 agaaatcaaa aaatacgaat ccttgattga agaacaaatt ccttatgcca actatgaatc
    13861 tgttagaaat gcagtcttct ccttagagaa aagactggct gacttaggtg ttgacagaaa
    13921 atcttgtcat atcgatttgg tgcctgaaaa ctttatcgaa tcacctcaag gacgacttta
    13981 tttgattgac tgggaatatt catcaatgaa tgatccaatg tgggatttgg ctgccctctt
    14041 tttagagtct gaattcactt cccaagagga agaaactttc ttatctcact atgagagtga
    14101 ccaaacaccg gtttctcatg aaaagattgc tatttataaa attttacaag atactatttg
    14161 gagtctatgg actgtctata aggaagagca aggtgaagat tttggtgact atggtgtgaa
    14221 tcgttaccaa agagctgtta aaggtttggc ttcttatgga ggttcagatg aaaagtaaaa
    14281 acggagttcc ttttggcctt ctctcaggta ttttctgggg cttgggtcta acggttagtg
    14341 cttatatctt ttcgattttt acagatttgt caccctttgt ggtggctgca gctcatgatt
    14401 ttttgagcat ctttatctta ctagcttttc tcttggtaaa agaagggaaa gttcgcctct
    14461 caattttctt aaatattcgc aatgtcagtg ttatcatcgg agccttgcta gcaggcccta
    14521 tcggtatgca ggccaatctt tatgcagtta agtatatcgg aagttcttta gcttcatctg
    14581 tatcggctat ttaccctgcg atttcagttc tattggcttt cttctttttg aagcacaaga
    14641 tttcgaaaaa tactgtattt gggattgtct tgattattgg agggattatt gctcagacct
    14701 ataaggttga acaggttaat tctttctaca ttgggattct ttgtgctttg gtttgtgcta
    14761 ttgcatgggg aagtgagagt gttcttagct cttttgccat ggaaagtgaa ttgagtgaaa
    14821 tcgaagccct cttaatccgt caagtaactt cgttcttgtc ctatcttgtg attgtgctct
    14881 tctctcatca gtcatttact gcagtagcca atggacaatt gctaggtctc atgattgttt
    14941 ttgcagcctt tgatatgatt tcctacttgg cttattatat cgctatcaat cgcttgcaac
    15001 cagccaaggc tacaggcttg aacgtgagct atgtagtatg gacggtcttg tttgcagttg
    15061 ttttcttggg tgcaccgcta gatatgctga ccattatgac gtcacttgtc gtcattgctg
    15121 gagtttatat tattattaaa gaataaagga gattcgtgtg aaagccatta tcttagcagc
    15181 gggattggga actcgcttgc gtcctatgac tgaaaatacc cctaaagcct tggttcaggt
    15241 taatcaaaaa cctttgattg agtaccaaat tgagtttctc aaagaaaaag gaatcaatga
    15301 catcatcatc attgttggtt atcttaaaga acaattcgat tacttgaaag agaaatacgg
    15361 tgttcgtctc gttttcaatg ataaatacgc tgactacaat aacttttact ctctctatct
    15421 tgtaaaagaa gaattggcca acagctatgt tattgatgct gacaattatc tctttaaaaa
    15481 tatgttccgc aatgatttga cacgttcgac ttattttagt gtttatcgtg aagattgtac
    15541 caacgaatgg ttcttggttt atggagatga ctacaaggtt caagacatta ttgttgatag
    15601 caaggcaggt cgcatcctta gtggtgtatc cttctgggat gctccaactg cagaaaagat
    15661 tgtcagcttt atcgacaagg cttatgtaag tggtgaattt gttgatctct attgggacaa
    15721 tatggttaag gataatatca aagagctaga tgtctatgtt gaagaattag aaggcaatag
    15781 catttatgag atcgatagtg tccaagacta tcgtaaatta gaagaaattc ttaaaaacga
    15841 aaattaaaga ttccaacatc tgacaaaata gtcggatgtt ttttgatttt ttacgaactt
    15901 ttacgaatag atagatgagt agaaaaagaa atggagttat ttatgaaaat cacaaactat
    15961 gaaatctata agttaaaaaa atcaggtttg accaatcaac agattttgaa agtgctagaa
    16021 tacggtgaaa atgttgatca ggagcttttg ttgggtgata ttgcagatat ctcaggttgc
    16081 cgtaatccag ccgtttttat ggaacgttat tttcagatag acgatgcgca tttgtcgaaa
    16141 gagtttcaaa aatttccatc tttctctatt ttagatgact gttatccttg ggatttgagt
    16201 gaaatatatg atgcgcctgt acttttattt tacaagggaa atcttgacct cctgaaattc
    16261 ccgaaggtag cggtcgtggg cagtcgtgct tgtagcaaac agggagctaa gtcagttgaa
    16321 aaagtcattc aaggcttgga aaatgaactg gttattgtca gtggtctggc caagggcatt
    16381 gacacagcag ctcatatggc agctcttcag aatggcggaa aaaccattgc agtgattgga
    16441 acaggactgg atgtgtttta tcctaaagcc aataaacgct tgcaagacta catcggcaat
    16501 gaccatctgg ttctaagtga atatggacct ggtgaacaac ctctgaaatt tcattttcct
    16561 gcccgtaatc gcatcattgc tggactttgt cgtggtgtga ttgtagcaga ggctaagatg
    16621 cgttcaggta gtctcattac gtgtgagcga gcaatggaag aaggacgcga tgtctttgct
    16681 attcctggta gcattttaga tggactatca gacggttgcc atcatttgat tcaagaagga
    16741 gcaaaattag tcaccagtgg gcaagatgtt cttgcggaat ttgaatttta aaaatgacct
    16801 aagctagaat tctaagaaaa aatcaatttt aagagaaaat gaacccaaca tttccataat
    16861 aaaacgcata ttagcaagtt tttaacactt gataatatgc gttttttcta agtggattag
    16921 tagagtagag gatttttctc atataatact cttcgaaaat ctcttcaaac tacgtcagct
    16981 tccatctgca acctcaaaac agtattttga gctgacttcg tcagtcttat ctacaacctc
    17041 aaagcagtgc tttgagcaac ctgtggctag cttcctagtt tgcgctttga ttttcattga
    17101 gtataaggga aagtatagtg aattgaaata agatgtgaac aactctatca ggaaagtcaa
    17161 attgatttat agaaatattt tagcagccaa ggtgcactgt tatagattca atacactata
    17221 atttagtgta attgagaaag gagaaatgat tgtgattgat gttggctagg ttatgttcaa
    17281 tgattcctac cgtctcaaat cttgtcagta aggaaaaata aattcttcaa aagtagagat
    17341 tacaaggctt gtttaagaaa gaattcaaag accttgacaa ataaaaataa aatggttatt
    17401 ataaaaaatg gtctgaaata gatgatgata cttttcgaaa atctcttcaa actacgtcag
    17461 ctcagctttg ccttgctgtg ttttgagcaa gctacggtta gcttccgagt ttgattttca
    17521 tttactagaa atgaaactga tgagagatat cagtagacat ttgagtcagg atattatgga
    17581 aaatgataaa aagagctcgt gagattggca tatcagacta ctaaagtatt gagtttgtta
    17641 ggattttagc gactagttag ctgggaaagg aagatatttg tgacaaataa taaactgtat
    17701 tcgttgatag aatttagaaa taaaatatat gaagaattag aactttccag aagtgattta
    17761 gcgattttac tatgtgccat gcttatcgcc tctatcggat taaatatgga ttcgactccc
    17821 gtgattattg gagccatgtt aatctctcct ttgatgacac ctattctggg agtggggctc
    17881 tctctagcta tatttgattt taaattgtta agaaaatctt ttaaaatatt agctattcaa
    17941 attcttgcca gtctaatagc ttcaacactt tatttttatc tttctcccat ttcgtatgct
    18001 agttcggaga ttgttgctag aacctctccg actatttggg atgttctcat tgcttttgta
    18061 ggagggatag caggtattat tggtgctagg aaaaaagaga ccaataatat tgttcctggt
    18121 gttgctattg caaccgcctt gatgcctcct ctttgtacag taggttatgc tattgcttct
    18181 gctaatctaa aatttatcat aggctcctct tacctattcc tcatcaattg tagctttatt
    18241 gtcattgcga cttatatagg tgttaggttg atgatggtta agaaacatta ttttaaagat
    18301 aatgaagaag actctaaaat gcgtaggatt ttgcttctag ttgctgtttt gctgatgatt
    18361 ccgagtttca tctctgcaac gactttagtg agagaaacgt tgaaaaaaga gtcccttaag
    18421 aaatttatat cagagcagtt tcaggggtat aatattttga aaaaaaccta ttctaaaaag
    18481 actcataccc taaagctaac catttcagga aattatttga cagaagaaga actcgatatg
    18541 atttcaagta agagaggtga ctatggttta agtgatgttt ctgttcaagt ttcacaattg
    18601 tctgattcag aacaacttag taaggaagag ctggtggagt atttcttcca gtatatcaag
    18661 gataaggaag caaaagaaaa ggagaaagcc aataaatttg atacagagtc tgaggagcaa
    18721 taatttcttg agaatagctg gtttctctcg tgagtcttct atgtatatca aaggaagact
    18781 gaggttttaa gtataaaact tttcttctat tatagtagct aagtcttgac agggttcaaa
    18841 aaatggttta cactttataa agtttattac tttgaaaagg tgtgatactg tggctacggc
    18901 aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc atcgtggagt cgcctgctaa
    18961 ggccaagacg attgaaaaat atctaggcag aaactacaag gttttagcca gtgtcgggca
    19021 tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt gaaaataatt atgaaccgca
    19081 atatattaat atccgaggaa aaggccctct tatcaatgac ttgaaaaaag aagctaaaaa
    19141 agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa ggagaagcga tttcttggca
    19201 tttggcccat attctcaact tggatgaaaa tgatgccaac cgtgtggtct tcaatgaaat
    19261 caccaaggat gcagtcaaaa atgcttttaa agaacctcgt aagatcgata tggacttggt
    19321 cgatgcccaa caagctcgtc ggatcttgga tcgcttggta gggtattcga tttcgcctat
    19381 tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc gttcagtcca ttgcccttaa
    19441 actcatcatt gaccgtgaaa atgaaatcaa tgccttccag ccagaagaat actggacagt
    19501 tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct tccttctatg gagtagatgg
    19561 taaaaagatg aaactgacca gcaataacga agtcaaggaa gtcttgtctc gtctgacgag
    19621 taaagacttt tcagtagatc aggtggataa gaaagagcgc aagcgcaatg ctcctttacc
    19681 ctataccact tcatctatgc agatggatgc tgccaataaa atcaatttcc gtactcgaaa
    19741 aaccatgatg gttgcccaac agctctatga aggaattaat atcggttctg gtgttcaagg
    19801 tttgattacc tatatgcgta ccgattcgac tcgtatcagt cctgtagcgc aaaatgaggc
    19861 ggcaagcttc attacggatc gttttggtag caagtattct aagcacggta gcaaggtcaa
    19921 aaacgcatca ggtgctcagg atgcccatga ggctattcgt ccgtcaagtg tctttaatac
    19981 accagaaagc atcgctaagt atctggacaa ggatcagctt aagctatata cccttatctg
    20041 gaatcgtttt gtggctagcc agatgacagc ggccgttttt gataccatgg ctgttaaatt
    20101 gtctcaaaaa ggggttcaat ttgctgccaa tggtagtcag gttaagtttg atggttatct
    20161 tgccatttat aatgattctg acaagaataa gatgttaccg gacatggttg ttggagatgt
    20221 ggtcaaacag gtcaatagca aaccagagca acatttcacc caaccgcctg cccgttattc
    20281 tgaagcaaca ctgattaaaa ccttagagga aaatggggtt ggacgtccat caacctatgc
    20341 gccaaccatt gaaaccattc agaaacgtta ttatgttcgc ctggcagcca aacgttttga
    20401 accgacagag ttgggagaaa ttgtcaataa gctcatcgtt gaatatttcc cagatatcgt
    20461 aaacgtgacc ttcacagctg aaatggaagg taaactggat gatgtcgaag ttggaaaaga
    20521 gcagtggcga cgggtcattg atgcctttta caaaccattc tctaaagaag ttgccaaggc
    20581 tgaagaagaa atggaaaaaa tccagattaa ggatgaacca gctggatttg actgtgaagt
    20641 gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt aaattctacg cttgtagcaa
    20701 tttcccagat tgccgtcata cccaagcaat cgtgaaagag attggtgttg agtgtccaag
    20761 ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt aatcgcctct tctatggttg
    20821 caatcgctat ccagaatgtg aatttacctc ttgggacaag cctgttggtc gtgactgtcc
    20881 aaaatgtggc aacttcctca tggagaaaaa agtccgtggt ggtggcaagc aggttgtttg
    20941 tagcaaaggc gactacgagg aagaaaagat taaataagag gaggggcccg aaagtaaatt
    21001 tcaggctcct tttggttaga acttgacaaa atacatcatt ttatgcgaaa ctagaagaag
    21061 attattttaa ctaggagaag ttatgcgtct tatctatctg ataattggtt ttttatcact
    21121 ggccttggct attgttgggg ttgttttacc cttgttgcct acaacacctt tccttttgtt
    21181 gtctattgct tgtttctcca gaagttccaa gcgattcgaa gactggcttt atcataccaa
    21241 gctctatcaa acatatgtag ctgattttcg cgagactaag tctattacgc gtgaacgaaa
    21301 gaaaaaaatc atcgtatcca tttacatttt gatggggatt tctatttatt ttgcccctct
    21361 cttaccagtc aaaatcggtc tgggtgcttt gaccatcttt atcacttatt atctcttcaa
    21421 ggtcattcca gacaaagaat agttaaaaca gtagttattt accttgataa aattgaaagc
    21481 atattcataa caatatgata taataaattt gaagtaatat tcaaggagaa tcaaatgatt
    21541 tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag cgatgcaggc tggagctcgt
    21601 cggattgaac tctgtgataa tctagcagtt ggtgggacaa cacctagcta tggagtgact
    21661 aaggcagcgg ttgaactggc agctaactac gatacaacca tcatgaccat gattcggcca
    21721 cgtggtggtg actttgtcta taatgaccta gaaattgcta tcatgctaga agacatttgt
    21781 ttgactgctc aggctggaag tcaaggggtt gtatttggag ctttaactgc tgataaaaag
    21841 ttggataagc ctaatctgga aaagttaatt gctgcatcaa aaggaatgga aattgtcttt
    21901 cacatggcct ttgatgaact aagtgatgaa gatcaaccgg aagctattga ctggctcagt
    21961 caagccggtg tcactcgtat cctaactcgt gctggtgtgt ctggcgactc cttagaaaaa
    22021 cgttttgttc actatcacag aattttggag tacgctaaag gtaaaattga aattctacca
    22081 ggtgggggga ttgaccttga caaccgtcaa acctttattg accaggtggg ggtaacacaa
    22141 ttgcatggta ctaaggttgt tttttaaaaa atagaaagga actgctagcc ttgggtagca
    22201 gttttcactt atgtttgaaa tttttaaatc ctatcaattt aatcaagaaa aggctcatga
    22261 ttatggtttt atagaaaata gcgaagtctg gacatatagt tgccagattt tgcaaggtga
    22321 ctttgtcatg actgtgtcca tcactgctga taatgtgaac tttcaagtct ttgaccaaga
    22381 gactggtgac ctctatcctc acgttcatat ggaaagcatg aggggaagtt ttgtcggaaa
    22441 tgtccgtgag gcttgtctgg agattcttta ccagattcgg aaggcttgtt ttgatgtgca
    22501 agattttatc tgtcatcaga ctaagcgtat catgactcaa gttcaggaaa agtatggaaa
    22561 ccagttggag tatctgtggg aaaaatcgcc tgatacagct gtattgcgcc atgaaggcaa
    22621 tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat aagctggaaa agggcagaga
    22681 aggacaagtg gaagcagtca acctcaagca tgaccaagta gctaatttgc tttcacaaaa
    22741 ggggatttat ccagccttcc atatgagcaa gcgctactgg attagtgtgt cccttgatga
    22801 tactttatca gatgaagaag tactggaatt gatagaaaaa agttggaact taacctctaa
    22861 aaaatgaaat attttaataa ttttcatgaa ctttcaatta gctaaatatt ctttactgaa
    22921 gaaattttta gaaaatatag gatttaccac actagaggaa tatggtgcca tcttcaaata
    22981 cctgattgag aatgtcaaga cggatcgtca gatcatctgt tcgcctcact gtcatgatga
    23041 cctcggaatg gcagtggcaa atagccttgc tgctgtcaag aatggtgcag gacgtgttga
    23101 agggactatc aatggtatta gggagcgagc tgaaaatgct gctttggaag aaattgcagt
    23161 ggctctcaat attcgccaag attactacca agtagaaacc agtattgtcc taaatgagac
    23221 catcaatacg tcagaaatgg tttctcgctt ctctggtatt ccagttccta aaaacaaagc
    23281 cgtcgttggt ggcaatacct tctcccacga atctggtatt caccaagatg gagtccttaa
    23341 aaatcctctc acttatgaga tcatcacacc tgaattggtt ggtgttaaga ttccgcttgg
    23401 aaaattatct ggtcgccatg cttttgttga gaaactgaga gaattggccc tagattttac
    23461 agaagaggat atcaaaccac tctttgctaa gttcaaggca ctggccgata agaagtaaga
    23521 aatcacagat gcagatcctc gagctttggt agctggaacc atggttgaaa atccagaagg
    23581 cttccacttt gatgatttac aacttcaaac tcatgcagat aatgacattg aagcgctcgt
    23641 tagcctagcc aatatggatg gtgagaaagt cgaatttaat gcgacagggc aaggttccgt
    23701 tgaagcaatc tttaacgcta tcgataagtt ctttaaccaa tctgttcgtt tggtgtccta
    23761 cactatcaat gcggtaacag atggaatcga tgcccaggat cgggttttgg tcactgttga
    23821 aaacagagat acagaaacca tctttaatgc agcagggctt gattttgatg tgttgaaggc
    23881 ttctgctatt gcctatataa acgctaatac ctttgttcaa aaagagaatg caggtgagat
    23941 gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa aggagaaggc tatggcaaag
    24001 aaaatagtag ctctagtagg agacggaatt ggcccagaaa tcatgtaggc tggtttagaa
    24061 gttctggagg ctctagctga aaaaacaggt tttgactatg agattgacag acgaccgttc
    24121 ggaggtgcag atattgatgc agcaggacct cccttacctg atgaaaccct taaggcaagt
    24181 agggaagcag atgctatcct actagcagct atcggtagtc ctcagtatga tggagcagcg
    24241 gttcgccctg aacaaggcct gatggctctc cgtaaggaac tcaatcttta cgctaatatt
    24301 cgtcctgtaa aaatctttga cagtctcaag tatttgtcac cactcaaacc ggaacgaatt
    24361 tctggtgtag actttgtcgt ggtgcgtgaa ttgacaggcg agatttactt tggagatcat
    24421 attcttgaag agcgcaaagc gcgtgatatc aacgactata gctatgagga agtggagcgg
    24481 attattcgca aagcctttga aattgcaaga aatcgcagaa aaatcgttac tagtatcgat
    24541 aagcaaaatg ttctagcgac ctcaaaactc tggcggaaag tagctgagga agtcgcacag
    24601 gatttcccag atgtaacctt ggaacaccag ctggtagact cagctgctat gcttatgatt
    24661 accaatcctg ctaagtttga tgttattgta acggagaatc tttttggaga tattttatct
    24721 gatgaatcaa gcgtcttatc tggtacactt gaggttatgc catcagccag tcattctgaa
    24781 aatggaccaa gtctctatga acctattcac ggttcagcac ctgatattgc aggtcaagga
    24841 attgccaatc ctacttccat gattttatca gttgccatga tgttgagaga tagtttcgga
    24901 cgttatgagg atgcagagcg tatcaaacat gctgttgaga caagtctggc ggcaggaatt
    24961 ttaacgagag atataggagg tcaggcttca acaaaggaaa tgacggaagc tattattgca
    25021 aggttatgaa gttagacgaa aaaattactc tagtcctttt gatttggaat gtcatcattt
    25081 tcttgattta tggcattgac aaattcaagg caagaagaag aacttggcgc atccaagaga
    25141 aaatcttact cattttagcc cttacttgtg gtggttttgg ggcctggtta gctggaatca
    25201 cttttcacca caagactcga aaatggtact ttaaaacagt ttggtttctt gggatggtga
    25261 ccacactagt agccttatat tttatttgga ggtaatggat ggcagggtct tcgagggaac
    25321 acgctgcttg ggttctagcg gactatggtt ttaaggtcgt gattgcagga tctttcggtg
    25381 acattcatta caataatgaa ctcaataatg gcctgttgcc aatcgttcag cctagagagg
    25441 ttagagagaa actagcccag ctaaaaccaa ccgaccaggt aactgtggac ttggaacaac
    25501 aaaaaatcat ctcaccagtt gaagaattca ccttcgagat agatagcgag tggaaacata
    25561 aactcctaaa tagtttggat gatatcggta ttaccttgca gtatgaagag ttgattgctg
    25621 cttatgaaaa acaacgacca gcctactggc aggattagaa aaaatagaaa aggaaatata
    25681 gtaaactgaa ataagatgta aacaaatgaa ttagagctta acatccattt ccagcaattt
    25741 tttagaaact acagtggact attctggatt caacacatta taaaattatg acaaaacaca
    25801 ttcacaagaa ggctacgaca ttttaaaagg tgagggcgga tgtatcgttt gccctactaa
    25861 agttggttac attatcatga ccagcaacaa ggcaggactt gagcgtaagt tcgcagccaa
    25921 agaacgtaag cgtaacaaac caggtgttgt tctctgcggt agcatggatg aacttcgcgc
    25981 tttagcgcaa ctcaacccag aaattgaagc attctactaa aaacattgga tgaagatatt
    26041 cttcttggtt gtatccttcc ttggaaacca gaagcctttg aaaaactcaa agcatacggg
    26101 aatggccgtg aagaacttat gactgatgta cgtggtacta gctgttttgt tatcaagttt
    26161 ggaaaagcag gtgaacaatt ggctgccaag ctttgggaag aaggtaaaat ggtctacgcc
    26221 tcatatgctt caatgacaaa acgattgaaa ctcgctatga gagcaaggtg taatggtgtc
    26281 tatggtcgat aaggacggca aactcatccc agaacaagga ggagcacgtt caacttcacc
    26341 agcaccagtt gtgatccgta aagggcttga cattgataaa atcatgatgc acctgtcaga
    26401 tacttttaac tcatgggact accgtcaggt tgagtattat taagataaaa aaagaagtct
    26461 agtgttatga gatattaaag ctcctaacac tggacttttt gtttagaatt tcttttcttt
    26521 ttctatagga tatggtattc tatgtagaaa atatatgtta ataagtaatg ccaatattta
    26581 aacatcatta gtaaaaggag ttagattgat gaataaaaga aaagttagtt tagaagattt
    26641 ttataaatgg tatagtctaa ataaagaaga gttattaaat aaggcaactg ttggtgaaaa
    26701 gtttaatgat aaattaaaag aagagtttct ccaggaatgg cctttggata ggattttaac
    26761 aatgtcaatc gatgaatatg taataggaaa gggacagcaa aataagtctt tatgctacgc
    26821 tcttgagaag ggaaaataca aaaatctatt tcttggaatt tctggtggct cagcttcaaa
    26881 atttggtatt tattggaata aaaaaacaaa caaatataaa gatcaagcta ataatgagat
    26941 ttcagagttg gatcagcgat tttcaaaatt aaaatcagat ttgtatgaaa ttatcaaaga
    27001 aggtattcgt tttaactttg aaaatcctat ttttgatatg aaaagatcaa caaatgaatt
    27061 tattggtcgt tctgctatgg tgacaaaatt actttgtatc tatactgagg gagatccttt
    27121 ctttggtgta aatattaata gtcagaaaga attttggaac cactttgttt ctcagacaaa
    27181 tcaaggtgga ccttatctgc aaaatcataa aataattgaa ctagtgtcca aaacttatcc
    27241 tgagttggag ccatcgaaat taggaactat gctttttgag tattctaagc tttttatgga
    27301 aaataaggaa gacaatagta caatggattc atcaaacaat tttcgtcatc aattaactca
    27361 atctctatta aagtctccaa acctcatcct ccgtggtgct cctggcacag gaaagactta
    27421 tcttgctaaa gaaattgcca aagaattaac ggatggcaac gaagaccaaa tcggatttgt
    27481 acaatttcac ccatcctatg attatacgga ttttgtagaa ggtttaagac cagtatcaaa
    27541 tggggatgga gctattgagt ttaggctaca ggacggtatt tttaaagatt tttgtcagaa
    27601 agcaaaagaa acccaattga ttggaggaca agataatttt gatgaggctt gggattctta
    27661 cttagaatat ataaatgttg ctgaagaaaa agaatatata acaaaaacat cttacttatc
    27721 tattaatagt agacaaaatt tgtcagtaaa ttatgatagt ggtgtttcag gatggtcact
    27781 acctagcaaa tatgtttacg agttgtataa agataaaaat tataataagc aagaatacta
    27841 caaaagtggt ggaaaaactg tcctagaaac attgagaaag agatttggtt tgaaagacta
    27901 tgtttcccca acagaaattg atactgataa gaaattcgtc ttcatcatcg atgaaatcaa
    27961 tcgtggggag atttctaaga tttttggcga actctttttc tctatcgacc ctggctatcg
    28021 tggtgaaaaa ggaagtgttt ctacccaata tgcaaatcta cacgaaactg atgaaaagtt
    28081 ctatatcccc gaaaatgttt acatcatcgg aactatgaat gatattgatc gttcagtgga
    28141 tacctttgat tttgctatgc gtcgtcgttt tcgttttgtt gaagttactg ccgagggtca
    28201 agttggcatg ttggataaag agctgaatat ccatgcagaa gaagcaaaaa ttcgtctaag
    28261 aaacttgaac gctgctatcg aaaatgttca ggaattaaac agtcattatc atattggacc
    28321 aagttatttt cttaagttga aggatgtaga ttttgactat gaattactct ggtctgatta
    28381 tattaagcct ctcctagaag actacttgcg aggttcttat gatgaggttg aaactttgga
    28441 aactttgaaa aaagcatttg aactgacaaa taatgagcaa aaagatcagg cagtagctga
    28501 tgacaatgaa ggtgatgaaa acgatgatgc ggattactga taatcaacac aagattatta
    28561 aagaaaaatt tgttgaagaa tatcctaaac taagcaatct tcttttagac agaaccttgg
    28621 aaagtctatc ccaagatgaa cgtattttca tttttccaaa tgatttgact catactcctg
    28681 atttggataa ggaccaaaag atttttgaaa cagtcaatca gaaaatcaag acagggaacg
    28741 tgattggttt tcttggatat ggtcaggaaa gattaacgat ttcctcacga ttttctgatg
    28801 agagtaatga ccattttttg cattatctct taaacaaggt tctttatatc aatctcacta
    28861 gtttagatgt tgctttgtct cgtgaagaga ggctttatca acttttgatg tatctcttcc
    28921 ccaagtatct acaagctgct attcgaaaag gtctttataa ggaatatcat cgattttttc
    28981 ataacgacag taatgttaag ggagtgattg atgtaagaag ccatctcaag aaaaatcttc
    29041 ctttcacggg aaatattgcc tacgcaacga gagagttcac ctatgataat cccctcatgc
    29101 agttggtccg tcacactatt gaatacatta agaatcagaa aagcattggt caaggggtac
    29161 tagataatct ctcaactagt cgtgaaaacg tatctgaaat cgtgcgtgta acgccctctt
    29221 ataaactagc tgatcgtgct aagattactc ggagaaatca atctaaacct atacgtcatg
    29281 catactttca cgagtacaga aacttacaag aactttgtct gatgatccta aaccaagaaa
    29341 agcacggttt agggtatcaa gatcaaaaaa tctatggtat tctctttgat gttgcctggc
    29401 tttgggaaga gtatgtttac accttgttgc caaaaggttt tgtacatccc agaaataagg
    29461 ataagacgga tggaatttca gtattttctg ttgggaaacg aaaagtatat ccagattttt
    29521 atgacagaga acgaaagatt gttctagatg caaaatataa aaaactggaa ttgactgaaa
    29581 aaggaatcaa ccgtgaggac ttattccagc tgatttccta ttcttatatt ttaaaagctg
    29641 agaaggctgg actgattttt cctagtatgg agcagtcagt aaatagtgaa ataggaaaag
    29701 tagctggcta tggagctcaa ttgaagaagt ggtctattcg aatccctcag aatgcctcat
    29761 cctatagtgc attttgtaaa atgatggaaa attcagaaga aaattttaaa gcgattattg
    29821 atgaagaagt ggggagaaaa taatttcccc tctttctttt atttttaaca caagtaaaac
    29881 ccgaacgata tattttaatt cataaaaaaa attgacaaaa actgtacttt ggtttataat
    29941 aaattaagga aacgtcggaa aaggcgtagt gatgcgagag cataggtagg tcattacaaa
    30001 agaaacgaga catcgatatg ttaaatgaat ttccaatttt tgattacgaa gatattcaat
    30061 tgattccaaa taaatgtgtc attaaaagcc gtgcagaagc ggatacaagt gtcactttag
    30121 gaaatcacac ctttaaacta cctgttgtgc cagcgaatat gcagacgatt ttggatgaaa
    30181 atgtagcaga gcaactggct aaaggtggtt acttctacat tatgcaccgt tttgatgagg
    30241 caggacgcat tccttttatt aaacgaatgc acaatcaagg gctcattgct tccatatctg
    30301 tcggtgttaa ggactatgag tatgatttcg ttagacagct caagactgat gctcctgagt
    30361 atatcactat tgatattgct catggtcatg cggatagcgt gatttctatg attcaacaca
    30421 tcaagaaaga attgccagat acctttgtca ttgctggaaa tgtgggaaca ccagaagctg
    30481 tgcgtgaatt ggaaaatgct ggtgcggatg ctactaaggt cggaatcggt cctggtaagg
    30541 tttgtatcac caaggttaag actggttttg gtacaggtgg ttggcagttg gctgctctac
    30601 gctggtgtgt caaggctgcg cgtaaaccga ttatcgctga tggaggaatt cgtactcacg
    30661 gtgatattgc caagtctatc cgcttcggtg ctagcatgat catgattggt tccctctttg
    30721 caggacatat tgaaagtcca gggaaaacga ttgaagtcga tggtgaacag ttcaaagaat
    30781 attatggttc agcctcacaa tatcaaaaag gtgcttacaa aaatgtggaa ggcaaacgta
    30841 tcttgcttcc tgctaaaggt catctgcaag acactttaac tgagatggaa caagaccttc
    30901 aaagtgctat ttcttatgca ggtggacgtc aggttgctga ccttaaacac gttgattatg
    30961 tgatcgtgaa aaactccatc tggaatgggg atgcttccca ctaagacggg gtctttgact
    31021 aaaaaacttg ttattagagc aaatttctgt tataataaaa caagtttcca cccttagtgt
    31081 aatggatatc acgtaagatt ccggttcttg agatgggggt tcgattccct cagggtggat
    31141 gtaaacattc taaaaagcct ttaatagggc ttttttcttt acactgctct aaatttaccg
    31201 ctaaaactga gaatctctgt ctaaagaatt tccaaatgct ttccagtccc gttttagagt
    31261 gactcagggg gctttttttg atataataaa aaggactgtt atcagttaga aagaggttgg
    31321 tatgaaagaa ttacaaactg tactaaagaa ccattttgca atcgaattta cagacaaaaa
    31381 gttactggaa actgccttta ctcatacgag ttatgccaat gagcaccgcc tcttaaaaat
    31441 ttcacataat gaacgcttgg aatttttagg agacgctgtt ctacagttat tgatttcaga
    31501 atatctgtat aaaaaatatc ctaaaaagcc tgaaggtgac ctatcaaaac tccgtgctat
    31561 gattgtccgt gaggagagtt tagctggttt tgcgcgtgat tgccagtttg accagtttat
    31621 caagttgggt aaaggggaag aaaaatctgg tggtcgcaat cgtgacacca ttcttggtga
    31681 tgcctttgaa gcctttcttg gtgcccttct tttggataag gatgtggcca aggtcaagga
    31741 atttatctat caagtcatga ttcctaaggt tgaagcaggc gaatttgaga tgattacaga
    31801 ctataaaacc catctccaag agttacttca ggtcaatggt gatgtggcta ttcgttatca
    31861 ggtgatttct gaaacagggc ctgctcacga taaggtcttt gatgtagaag ttcttgttga
    31921 aggtaagagt atcggtcaag gccaaggtcg ttctaagaaa ttagcagagc aggaagctgc
    31981 caaaaatgcc gttgagaagg ggctggattc atgtatttaa aggaaatcga aattcagggg
    32041 ttcaagtctt ttgctgataa gaccaaggtc gtttttgacc aaggtgtgac ggcagttgtt
    32101 ggaccaaatg gatctggaaa gtccaatatt acagaaagtc tgcgttgggc tttgggggag
    32161 tctagtgtca agagtctccg tgggggcaag atgccggatg tcatctttgc tggaacagaa
    32221 agtcgcaaac cgctcaatta tgcttctgta gttgtgactc tggataatca tgacggattt
    32281 atcaaggatg caggtcaaga aatcagggtg gaacgccata tctatcgtag tggagatagc
    32341 gaatacaaga ttgacggcaa gaaagtccgt ctgcgtgata ttcatgacct cttcttggat
    32401 actggattgg gacgagattc cttctctatt atttcccaag ggaaggttga ggagattttt
    32461 aattccaagc ctgaggaacg acgagctatt tttgaagaag ctgctggagt tttaaaatac
    32521 aagactcgca gaaaagaaac cgagagtaaa ctgcagcaaa ctcaggataa tctggaccgc
    32581 ttagaggaca ttatctacga gttggataat caaatcaagc ctcttgagaa gcaagctgag
    32641 aatgcccgta agtttttaga cttggaagga caacgtaagg ctatttattt agacgttctg
    32701 gttgctcaaa tcaaggaaaa taaggctgaa ctagagtcga cagaagaaga gttggctcag
    32761 gttcaagaac tcttgatgag ttattaccaa aagcgtgaaa aattagaaga agaaaatcaa
    32821 actcttaaaa agcaacgcca agatttacag gctgaaatgg ccaaagacca aggcagtttg
    32881 atggatttga ccagtctgat tagtgactta gagagaaaat tagccctatc gaaactggaa
    32941 tctgagcaag tagccctcaa tcaacaggaa gcacaagccc gtttggctac tttggaggat
    33001 aagagaagtt cactcagcca agaaaaatct gataaagaaa gctctttagc cctcttggaa
    33061 gaaaatctag tccaaaataa tcaaaaactc aatcgattag aggctgaatt gctagctttt
    33121 tcagatgatc ctgatcagat gattgagctc ttacgtgaac gctttgtggc ccttttacaa
    33181 gaagaagcag atgtctcaaa ccaactgacc cgtattgaga atgagttgga aaatagtcat
    33241 cagctttctc aaaaacaagc agatcaacta gaaaagctga aagaacagtt ggctacagct
    33301 aaagagaagg ctggtcagca aaaggctgag cttgaaactg ccaaggagca ggttcagaaa
    33361 ttattggccg actatcaagt ctgtgctaag gagcaagagg agcagaaaac ttcctatcaa
    33421 gctcaacaaa gtcaactctt tgaccgtctg gatagtctca aaaacaagca ggctagagcg
    33481 caaagtttgg aaaatatcct gagaaatcat agtaactttt atgcaggtgt taagagtgtt
    33541 ctccaagaga aagatcgtct aggtgggatt attggagcag ttagtgagca cctgaccttt
    33601 gatatgcatt atcaaactgc cctagaaatt gcgcttggag cgagtagtca gcacattatt
    33661 gtagaagatg agaatgcggc aaccaaagcc attgatttac tcaaacgaaa cagatctggt
    33721 cgtgcaacct tccttccttt gaccactatc aaggctcgta cgatttctag tcagaaccaa
    33781 gatactattg ctgcaagtcc aggatttctg ggcatggcag atgagctggt tactttcgat
    33841 actagactgg aagccatttt caagaatttg ctagctacaa cggccatttt tgataccgtg
    33901 gagcatgcgc gtgcagcagc gcgccaggtt cgttatcagg ttcgtatggt gacattggac
    33961 ggaacagagc tgcgcacagg tggttcttat gcaggtggag ctaatcgcca gaataacagt
    34021 attttcatca agccagaact ggagcaatta caaaaagaaa ttgctgaaga agaagcaagt
    34081 ttgcgttcag atgaagtgag tttgaagaac ttgcaagatg agctagctag attgacagaa
    34141 agattagaag ccatcaaatc tcagggagag caggctcgta ttcaggagca aggcttgtcc
    34201 ctcgcctatc agcagaccag tcagcaagtt gaagagctag aaactctttg gaaactccaa
    34261 gaagaggaat taaatcgtct ttctgaggga gaatggcaag cggataagga aaaatgccaa
    34321 gagcgcctta ctacaatcac tagtgaaaag aataatctgg aagctgagat tgaagagatt
    34381 aagtctaata aaaacgccat ccaagaacgt tatcaaaact tgcaggaaga gctagctcaa
    34441 gctcgtctac ttaagacaga actgcaaggg caaaaacgtt atgaagttgc tgatattgaa
    34501 cgcttaggta aggaactaga taatcttgat attgagcaag aagaaattca gcgccttctt
    34561 caagaaaagg ttgacaatct tgagaaagtt gatacggatt tgctcagtca acaggctgat
    34621 gaagccaaaa ctcaaaaaac aaatctccaa caaggtttga ttcgcaagca gtttgagttg
    34681 gatgatattg agggtcaact ggatgatatt gctagtcatt tggatcaggc tcgccagcag
    34741 aatgaagagt ggattcgcaa gcaaactcgt gctgaagcca agaaagaaaa ggttagcgag
    34801 cgcttgcgcc atctacaaaa tcaattaaca gaccagtacc agattagcta tactgaagca
    34861 ctagaaaaag cgcatgagtt ggaaaatctc aatctggcag agcaagaggt gcaggattta
    34921 gagaaggcta ttcgctcact gggacctgtc aatttagacg ctattgaaca gtacgaagaa
    34981 gttcacaacc gtctggattt cctaaatagc caacgtgatg atattttgtc tgcgaaaaac
    35041 ctgcttcttg aaaccatcac agagatgaat gatgaggtca aggaacgctt taaatcaacc
    35101 tttgaggcca ttcgtgagtc ctttaaagtg accttcaagc agatgtttgg tggaggtcag
    35161 gcagacttga tattgactga gggcgacctt ttaacagctg gtgtggagat ttctgttcaa
    35221 cctccaggta agaaaatcca gtcgcttaac ctcatgagtg gtggtgaaaa agctctatcg
    35281 gctcttgcct tgcttttctc cattattcgt gtcaagacca ttccttttgt catcttggat
    35341 gaggtagagg ctgcgctaga cgaagccaat gttaaacgtt tcggggatta tctcaaccgc
    35401 tttgataagg acagtcaatt tattgtcgta acccaccgta aggggaccat ggcagcggcc
    35461 gattctatct atggagtgac catgcaagaa tcgggtgttt caaagattgt ttcagttaag
    35521 ttaaaagatt tagaaagtat tgaaggatga caattaaact agtagcaacg gatatggacg
    35581 gaaccttcct agatgggaat ggacgctttg atatggatcg tctcaagtct ctcttggctt
    35641 cctacaagga aaaagggatt tactttgcgg tggcttcggg tcggggattt ctgtctctgg
    35701 aaaaattatt tgctggtgtt cgtgatgaca ttattttcat cgcggaaaat ggcagtttgg
    35761 tagagtatca aggtcaggac ttgtatgaag cgactatgtc tcgtgacttt tatctggcaa
    35821 cttttgaaaa gctgaaaacg tcaccttatg tagatatcaa taaactgctc ttgacgggta
    35881 agaagggttc atatgttcta gatacggttg atgagaccta tttgaaagtg agtcagcatt
    35941 ataatgaaaa tatccaaaaa gtagcgagtt tggaagatat cacagatgac attttcaaat
    36001 ttacaaccaa cttcacagaa gaaacgctgg aagctggtga agcttgggtc aatgataatg
    36061 tccctggtgt caaggctatg acaactggct ttgaatctat tgatattgtt ctggactatg
    36121 tcgataaggg tgtagctatt gttgaattag ctaaaaaact tggtatcaca atggatcagg
    36181 tcatggcttt tggagacaat cttaatgact tacatatgat gcaggttgtg ggacatcctg
    36241 tagctcctga aaatgcacga cctgaaattt tagaattagc aaagactgtg attggtcacc
    36301 ataaggaacg gtcggttata gcttatatgg agggcttata atggcagata taaaattgat
    36361 tgcattggac ttggacggga ccttgctgac tactgataaa aggctgacgg atcgtaccaa
    36421 ggaaaccttg aaagctgcgc gtgatcgtgg tatcaaggtc gtattgacaa ctggtcgtcc
    36481 cttaaaagcc atggatttct ttctccatga gttagggact gacggtcagg aagatgagta
    36541 taccattact tttaatggtg gattagttca gaaaaataca ggagaaatcc ttgataaaac
    36601 agtcttttca tatgatgatg tggcacgttt gtatgaagaa acagagaaat tatcactgcc
    36661 tctcgatgcc atctcagaag gaacagttta tcaaatccaa tcggaccaag aaagtcttta
    36721 tgccaaattc aatccagctt tgacctttgt tccagtggac tttgaagact tatctagtca
    36781 aatgacctac aacaaatgcg tgactgcctt tgctcaagaa cccttggatg cagccattca
    36841 gaagatttct ccagaattgt ttgaccaata tgaaatcttt aaatcacgtg aaatgttgct
    36901 agaatggtca ccaaagaatg ttcataaagc aacaggtttg gcaaaactaa tcagccatct
    36961 tggaatcgac caaagtcaag tgatggcttg tggtgacgag gccaatgacc tctctatgat
    37021 tgaatgggca ggtcttggtg ttgctatgca aaacgctgtt cctgaagtaa aggcagccgc
    37081 aaatgtagtg acgccgatga ccaacgatga ggaagctgtc gcctgggcta tcgaagaata
    37141 tgtgctaaag gagaactaag atatgggatt gtttgaccgt ctattcggaa aaaaagaaga
    37201 acctaaaatc gaagaagttg taaaagaagc tctggaaaat cttgatttgt ctgaagatgt
    37261 tgatcctacc ttcacagaag ttgaggaagt ttctcaggaa gaagcagagg ttgaaattgt
    37321 tgaacaagct gtgttccaag aagaggaaat ccaagacaca gttgaagaaa gtctggattt
    37381 agagccagtt atagaagttt ctcaaaaaga agtcaaagaa tttccacact cagaagaagg
    37441 gaatactgag tttctagaga ctgtagaaga aaataattct gaaattcttg aagcagaaag
    37501 gcctcaaaca gaagaaactg ttcaggaaaa atatgaccgc agtcttaaga aaactcgcac
    37561 aggtttcggt gcccgcttga atgccttctt tgctaacttc cgctctgttg acgaagaatt
    37621 tttcgaggaa ctggaagaac tgttgattat gagtgatgtt ggtgtccaag tcgcttctaa
    37681 cttaacggag gaactacgtt acgaagccaa gcttgaaaat gccaagaaac ctgatgcact
    37741 tcgtcgtgtc atcattgaga aattggttga gctttatgaa aaggatggta gctacgatga
    37801 aagcatccac ttccaagata acttgacagt tatgctcttt gttggtgtga atggtgttgg
    37861 gaaaacaact tctatcggaa aactagctca ccgctacaaa cgagctggta agaaggtcat
    37921 gctggttgca gcagatacct tccgtgcggg tgcagtagct cagctagctg aatggggccg
    37981 acgagtagat gttccagtag taactggacc tgaaaaagct gatccagcca gcgtggtctt
    38041 tgatggtatg gaacgtgccg tggctgaagg tatcgatatt ctcatgattg atactgctgg
    38101 tcgtctgcaa aataaggata accttatggc tgagttggaa aagattggtc gtattatcaa
    38161 acgtgttgtg ccagaagcac cacatgaaac cttcttggca cttgatgcat caacaggtca
    38221 aaatgcccta gtacaggcca aagaattttc gaaaatcaca cctttaacgg gaattgtttt
    38281 gactaagatt gatggaactg ctcgaggagg tgtggttcta gccattcgtg aagaactcaa
    38341 tattcctgta aaattgattg gttttggtga aaaaatcgat gatattggag agtttaactc
    38401 agaaaacttc atgaaaggtc tcttggaagg tttaatctaa tcagaagcaa aaatcctgca
    38461 aggcataaac ttgcaggaaa tttttttatt ctaagcgacc atcttgacga taggcgatat
    38521 ctggttgcca agtccatttg gcaccgaatt tttcaagtag gtcaaagctg gcttgaggtc
    38581 ccatgcttcc agctttatag tcatgaagtg gggcaccatt ttcatcccag agctcttcaa
    38641 tacggtcaat caacttccat gatgcaccaa cttcatccca gtggctaaag ttagttgagt
    38701 tgttatttag gacatcataa atcaatttct cgtatggttc tggagaagca ccagttgcag
    38761 tcgcatctgt acggtaatca agtgagttag gagccaagtt aaattcttct cctacttgct
    38821 tcccatttag gctaagagag aagccttctg ttggttgaat atagatggtc aaaatatttg
    38881 gagcaagtgg ttctccaaag atagaatcca tttgtttaaa gacgatgttg acatgagttc
    38941 ctttttcagt cagtcgttta cctgtacgga aaaagaaagg aacactacgg aatcgatcgc
    39001 tgtctacaaa gaaggcacca gatgtaaagg tttcagttgt tgattctgga ttcacatttg
    39061 gctcgctacg ataagagatg tatttcatgc catcaatctt accagagcgg tattgcccac
    39121 ggataaagtg ttctttgagt tcttcatcag ttggatgata gaggttttta aagaccttaa
    39181 tcttttcagc acgaatctcg tcttttgtga agcttgctgg tttgtccatg gcgaggagcg
    39241 aaagaagttg tagagtgtgg ttttggacca tgtcacggag ggcaccggat tggtcatagt
    39301 agccaccacg ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca ttgtcgataa
    39361 aatccttgtt ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca aagatgcttt
    39421 ggatcatttc cttaccaaga taatggtcga tacggaaaat ttgttcttcg tcaaatgttg
    39481 ctaggagttc gtcattcaac ttgcttgcag ttgcgtaatc tgtaccaaat ggtttttcaa
    39541 cgatcaagcg ctcaaaacct ttgccatcga caatgttttc agatttgagg tgtttggcaa
    39601 tggttccaaa gaactgaggt gccatagaca agaagaagag cttattgtgt tcagcttggt
    39661 atttttcatt aagctcagct tgtaattgac gcaaagcaat ataatgttcc gaatcattga
    39721 catcatggct ttgatagtag aagtggctag caaattcttg ggcttgctcg gtactatctg
    39781 ccaaatcaag gatggactcg acaactacag attcaaaata ttccttactc caaggtctac
    39841 gggcagttcc aataacggca aagtgcttgg aaagattgcc ggatttatat agtctaaaaa
    39901 gggaagggta gagcttgcgt ttagccaggt ctccactcgc accgaaaatt gtaacaataa
    39961 ccttagatga catctagcta cctaatttct atttttattc ctagtcttgc taggtatgag
    40021 gaaacctcat ttcataaact taattctaac ataattttcc gaaaaatcaa aaattccaat
    40081 acgaagtaga aaaactgcaa ggaaatcctt acagtttgag tttagacgtt taagacctta
    40141 tctaagaact ctttcagacg agggtgttgt gggttatcaa agatttggtc aggtgttccg
    40201 tcttcaagga actcgccatc tgcagtaaag ataacgcggt tggcaacctg acgagcaaat
    40261 cccatctcat gggttacgat aatcatggtc ataccttgct cagccaattc cttcataacg
    40321 ttaagtacgt ctccaaccat ctcagggtca agggcagaag ttggttcatc gaagagcatg
    40381 atgtctggat tcattgctag gccacgagcg atggccacac gttgtttttg accacctgat
    40441 aggctatctg gattggcatt agctttatct gctagtccaa ccttttcaag caactccatt
    40501 cccaattcct cagcttcttc cttagtcatc aacttgtgct caataggagc aaaggtgatg
    40561 ttgtccaata cagacatatg agggaagagg ttgaagtgtt ggaataccat gccgatattt
    40621 tcacggacgt ggtcaacatt ggttgttttt tcagttaaat catagccgtt cacagtgatg
    40681 tgaccgctag tgacttcttc taaaagattg aggctacgga ggaaagttga cttaccagaa
    40741 cctgaaggac cgatgataca aacaacatct ccttcataga acttagtcgt aattcctttt
    40801 aggacttcat tttttccata gtgcttgtgt aaatcattta catcaatttt taattttgcc
    40861 attaacgaat cctcttttct aagcgtttcg ctagtctagt caaaagtgtg ataattacaa
    40921 gatagaagat agcaaggatt gcatacatct tgaaactttg gtagttacga gcaatgataa
    40981 tcttaccagt ttggaagagt tcaaccaaac cgatagcaga tacgatagtt gtatctttaa
    41041 gagcgataac gaattggttg acaaagtttg gcaacatcaa tttagttgct tgtggcaaga
    41101 taatcttacg catggttttt ccataagaga tacccaagct tcggctggct tccatttggc
    41161 caactggaac ggcctgaata ccaccacgaa cgatttcagc gatataagca gccgcattga
    41221 gtgagagggc aatggttcca gctacaaagt cgttaattgg gctttgttgg cctgtgatag
    41281 actcgatgaa gtttggaatt ccccagaaga tgaaggctgc aagaatcatc aatggaatac
    41341 cacgaataac gtcaacgaaa atctcagaga tgacgcgaag agatttgtat gggctaacgc
    41401 taaacatacc gaagataatt ccgatgacaa tggcaatagc aaatgagata agagctagag
    41461 caagagtgat accaagaccg ctaaggagtt gtttgtagtt gttttgaagc aagccccaga
    41521 gcgttgtttc gtcaacagta cttgttgaag cagttgaaga ttcgctagct aggtatttgt
    41581 caagaatctt ttggaattca ccgtttgctt taaggtttgc aagtccgttg ttgaacattt
    41641 caatcagttc tggatttgct ccttttttaa cggcaaaggc tgtttcaccg attggagttc
    41701 cagagattgg agttttcaat ttttgacctt ggctgataga atatttgaga acaggttcat
    41761 catccataac ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa gaaccatcag
    41821 caaaggtttt gattttgtaa ccgtatttgc tttgattttc tgttaggaag gtttgagaag
    41881 cagttccgtt tttaacaccg actgtctttc cttttagatc ttcataagaa gcaatattgc
    41941 ttgattcttt gacaccaaga atggtattag cagtgtagta tgattctgag aagtcaaaag
    42001 ttgccttacg agcatctgtg acagacatcc cagcaatgat accatcggct tgaccagctt
    42061 ggacagcact gatagcagca tcaaaaccag ggttggtgat ttcaatttca aaaccttggt
    42121 ctttagcgat tgccttaatc aattccatat caataccagt gtattggttg cttgaatttt
    42181 ggaaaacaaa aggtgcaaaa gaagaatcgc tggcaatgat atatttagcc ttaacaggaa
    42241 tagcttttaa tcctgcgaga gtagttgtag ttggcactgc tgaagatgat gaagcagtcc
    42301 atttcttgat aattttatca agactaccat cttttttcat ttcagccaag gcttggttaa
    42361 attcagtaac caggtgctcg tatttacttc cttttttcac accgaaagca aaacttccta
    42421 cagcttcacc atccatttca atatggagat cttgaccttg gttaatggca tattcgataa
    42481 caggtttgtc atccatcatg gcatcgatgg caccagcact caagctgttg ttcattaaat
    42541 caccagtgtc aaatgtttta atagtaaagc cgtatttatc tttgattgtt tcaaggaaac
    42601 gttgagcggc agttccgttt ttaacaccaa cggttttgcc agttaattgg tcgtacttgc
    42661 taattttgtg tgactttgta gtagcaatga caacttttgt atcatagtaa gtatcagaca
    42721 tggtgaagac tttttcacgt tctttagtct ttgtcatccc tgccatgata gcgtcggctt
    42781 gcccagcttg aaccgcattg actgctgcgt caaatccagg ataggacatc tgaatgttcc
    42841 agcctttaat ctcagcgact ttgttaataa tgtcaacatc aattccttta taagtttgat
    42901 ctgaatcttt aaactcaaaa ggtgcatagg cggtatcaga aacaatctta atcgtttctg
    42961 ctttggcaat acctaatgag aaaattggga ataaaattag caaaaatgct agaaattttt
    43021 tcttcatttt tagtctcctt ttccgaatat tctctcatta tatcagaaaa agtaaaaaaa
    43081 ggcaaattgt tatatttttc gtgtcagaaa atataacatt gatttttcct tttctttctt
    43141 gaattgctat taaaaagtgc tataataata gtatatatag aagaaaagag gacggggata
    43201 tgaagaacaa aagaatattt aaagacttcc aagcttcaaa aatgagttta aacatttaca
    43261 caagcccctt gttagccttt gtttttgtct tcataggaga gtttgtggct tttactttgt
    43321 atggtattgg cttgttagct ctcatcggac ttgctagaaa ttttggagag gctggtcaaa
    43381 atcttgcaag ctacttgcag accttgcaac agagcttgac ggataaaaca agtgactttc
    43441 gtttaatttt aggattactg gcctttggtt ttattcttaa cactgtgttc agatggacaa
    43501 gaaaagttga gaaaagacct attcgaacct tgggatttta tagagagaat ttcctcagca
    43561 atcttctgaa aggatttagt ctaggcttgg cactttttct tctgaccttg ttaggtttag
    43621 tggtcttagg tcaatatcgt ttggaatcca ttcacttgaa tccttattct cttgcctttg
    43681 tcgtctttac tatcccattt tggattttac aggggacagc agaagaagtg gtggcccgtg
    43741 cttggctact tcctcaattg gcctcaagaa ccaatctaaa actagctatt cttatatcta
    43801 gcctgttctt taccctgctt catatgggca attctagcct cacccctcta tctctagtaa
    43861 atctcttttt attcggagtt gccatggctc tttatcttct caaaactgat acagtttggg
    43921 gtgttgcagg tattcatggt gcttggaatt ttgctcaggg taatctcttt gggattttag
    43981 ttagtggtca accgtcagga acgtctctga tgaccttttt accacaaggc aatcaagatt
    44041 ggctatcagg tggttctttt ggcatagaag gttccattat gacaagtctg gtattactac
    44101 tgctgattgt ctatcttgct aataaattaa agaaagaaaa tgaaaggatg tgacttcggt
    44161 ccgtcctttt cttcgtgaaa atactataag tatgctaaaa taggaatagc acatggagag
    44221 aggattctta tgatcaatca cattacagat aatcaattta aactagtatc aaaatatcaa
    44281 ccatcaggag atcaacccca agctatcgag cagttggtgg ataacattga ggggggagaa
    44341 aaagctcaga ttctgatggg ggcgactgga acagggaaga cctatactat gagtcaggtc
    44401 atttctaaag tcaataaacc aactctggtt attgcccaca ataaaactct ggctggtcag
    44461 ctctatgggg agtttaagga atttttccct gaaaatgcag ttgagtattt cgtatcctac
    44521 tatgattatt accagccaga ggcctatgtc ccttctagcg atacctatat tgagaaggat
    44581 agttctgtca atgacgagat tgacaagctt cgccactcag ctacctcagc ccttttggag
    44641 cgtaatgatg ttattgtcgt ggcctcagtc tcttgtatct atggtttggg ttcgcccaag
    44701 gaatacgctg atagtgtcgt tagtctccgt cctggtctag agatttctcg tgataaactc
    44761 ttgaatgact tggtcgatat tcagtttgaa cgtaatgata ttgatttcca acgcggaaga
    44821 tttcgtgttc gtggggatgt ggtagagatt ttcccagctt cccgagatga acatgccttt
    44881 cgagtagaat tttttggaga cgaaattgac cgtattcgtg aagttgaggc tctgacaggt
    44941 caggtgttgg gagaagtgga tcatttagcg attttcccag cgacacactt tgtgaccaat
    45001 gacgaccaca tggaagttgc cattgcaaag attcaggccg agttggagga gcagttagct
    45061 gtctttgaaa aggaaggtaa actgcttgaa gcccagcgtt tgaaacagcg gacagagtat
    45121 gatatcgaaa tgttgcgtga gatgggctat accaatgggg ttgaaaatta ttctcgccac
    45181 atggatggac ggagcgaagg agagcctcct tatacgcttc tcgacttctt cccagatgat
    45241 ttcttgatta tgattgacga gagtcatatg accatagggc aaatcaaggg catgtacaat
    45301 ggagaccgtt cgcgtaaaga aatgctggtt aattatggtt tccgtttgcc gtctgctttg
    45361 gacaatcgtc ctctccgtcg ggaggagttt gagagtcacg ttcatcagat tgtttacgtt
    45421 tcagcgacac ctggtgacta tgaaaatgaa cagaccgaga cagtgattga gcaaatcatt
    45481 cgtccaacgg gactcttgga tccagaggtg gaagtccgtc cgactatggg acagattgat
    45541 gacctcttgg gtgaaatcaa tgcccgcgtt gaaaaaaatg agcgtacctt tatcacaact
    45601 ttgaccaaga aaatggcaga ggacttgacc gactacttca aggaaatggg tatcaaggtc
    45661 aagtacatgc actcggatat caagaccttg gaacggacgg agattatccg tgacctgcgc
    45721 ttgggtgtct ttgatgtctt ggtcggaatt aacctgctcc gtgaaggaat tgacgttcct
    45781 gaagtgagcc tcgtagctat tctcgatgct gacaaggaag gtttccttcg caacgaacgt
    45841 ggactcatcc agactattgg acgtgctgct cgtaacagtg aaggccatgt catcatgtat
    45901 gcagacacgg ttacccagtc tatgcaacgt gctatcgatg aaactgcccg ccgtcggaaa
    45961 attcagatgg cctataatga agagcatggt atcgtaccac agacaatcaa gaaagaaatc
    46021 cgtgacctga ttgccgtgac caaggcagtt gctaaggaag aggacaagga agtcgacatc
    46081 aatagcctca acaaacaaga gcgtaaagaa ctcgtcaaga aactagaaaa acaaatgcaa
    46141 gaagccgtcg aagtgcttga ctttgaactg gcggctcaga tccgtgatat gatgttggaa
    46201 gtcaaggcct tggattaggg gaatagtatg atttatttaa gaaagttaaa gagagaagat
    46261 ttgatgtctt tatgggaaat ggcttattca caacttaatc cagtttggaa acagtatgat
    46321 gctccctatt atgatgatta tcagtatttt tcaaatttta aagaattcga actacaaaaa
    46381 tcagaatcca ttttaagcaa ctcaaatcgc cttggtattt ttgttgatga taaactagtt
    46441 gggactgttt cgcgttattg ggtatgtaaa caaacaagat ggatggaatt gggaattggt
    46501 atttatgata aaaaattctg gaacactggt attgggaaag ttgctatgtt gcagtggata
    46561 gataggacgt ttcaggatta cttggagttg gagcatctgg gtttgacaac ttggtcaggg
    46621 aatcttggta tgatgaaact tgctgaaaaa ttaagaatga aaaaagaagc tcatattcca
    46681 aaagttcgtt attatcaagg taaatatttt gatagtatta aatatggtat tttgagagaa
    46741 gactgggaga aaataaatga cggttattat caaatcaatg gaaactccta aagagataga
    46801 aggtaaatcc cttgttcact ggcaaatgtg gagagaggct tatgatgacc ttttgcctgc
    46861 agaatttcag gagacaatga cattagaaag atgtcgactc tttagtcaaa agtatccaga
    46921 aaatacattg attgcgatag gtgatctgaa ggtagttggt tttatcagtt atggtaactt
    46981 tcgtgatgag actatgcaag ctggtgaaat tattgcttta tatgttttaa aagactatta
    47041 tggaaaaggt atcgcacaaa agttaatgaa agcagctttg actgctctta atcatttttc
    47101 tgaaattttc ttatgggtat tgaaagataa caagcgcgcc attgctttct atcaaaaaat
    47161 gggttttact tttgatggac aagaaaaaat acttgaactt ggaaagccta taaaggaaaa
    47221 acgaatggtg ttctattcta aataatttta aaaaagtaaa agataatatc tctggtagta
    47281 agtctgaaaa tttaataaat tagaaagcga gtaaatttat gtcccgttcc caattaacaa
    47341 ttttaacaaa tatctgtctg attgaagacc tcgaaactca gcgcgtggtg atgcagtatc
    47401 gcgcccctga aaacaatcgc tggtctggtt atgcctttcc tggaggtcat gtagaaaatg
    47461 atgaggcttt tgcggagtct gtcattcgtg aaatctacga agaaacaggg ttgactatcc
    47521 aaaatcctca acttgtcggc attaaaaatt ggccactaga tacaggtggg cgctatattg
    47581 tcatttgtta taaggcgact gagttctctg gtagccttcg gtcttcagat gaaggagaag
    47641 tttcttgggt gcaaaaagac cagattccaa acttggatct ggcctatgat atgctaccat
    47701 tgatggaaat gatggaagct cccgacaagt cagagttttt ctaccctcgc cgtacagaag
    47761 acgattggga aaagaaaatc ttctagtctt ttactaaata acctagctga tccaaggcct
    47821 cctcgatata gtggaggtct tgttgtgttt cggcttcgac taggtggtaa tggatgccat
    47881 ctgtcaattc agatagaggt ctaaagtcag aatgctcgac ttgttctaga aaatgttgca
    47941 catctctgcg acaagacagt ttaagcaagg tttcaatttc tccataaacg ggatggtcaa
    48001 tcaaggtatt ctggacatgc ccaccattat cgacaatagc aaggagttcc tgaccgattt
    48061 cttcaacttc atgtttcact ttgaaaagtt tgtgaacata aggattggta tcaatttgct
    48121 tatagatgta gccacgattg gtggatagga taggagcgcc atcggctctc aaaattgcaa
    48181 tatcctgcac aatgacctga cgtgtgacat gaaaatgttc cgccaaactt tggccattaa
    48241 gggctttagg agcttctttc aagagttgga gcagggcttg tttgcgatct tttgtcatag
    48301 cttttccttt taacggcgtt ttcgaagcac tttatagaca gctagtgcta atgtatagtc
    48361 taccatacta tggataattg tgccaaatcc aactagtaca aatagaacat agaacatatt
    48421 ttctacattg gtacccgaag ttgcgtaaaa aaggacacag gctaatactt cagcaagggc
    48481 atgaacaaca gccaaaacaa aattgaaaac ccaggaagat tttggtttat ctagggtatc
    48541 ggggaatttt tgtaggtaaa gagctcctaa agcaccaaaa gatatatggg aaaaagcccg
    48601 aaaaacgata accatgggat agccagccat caaaaatcca aaactagagg ctaggatgac
    48661 aaaaactgcc atcaagggcg acaagaacat ggctataaaa atagcgatgt ggctccccaa
    48721 agtataggaa gcaggtggaa tgacaatctt gaaaggcata acaattggaa tcaaaatcgc
    48781 aatagccgtt aaaagggctg tcattgtcat aaattgtgtc tttttccgtg tattcacaag
    48841 aatctccttt ttaactgcat atacactagt atggtacaat aaaccagaca ataaagcaag
    48901 aatttacttg ggtttataga tcatttttta gttaaaagtt atagtagatg gaaactagaa
    48961 tagtccacct ctacttctaa aacattgtta gcgatttgac tgtcctgatc gatttgtcct
    49021 gttcttattt cgttttacta tagtaaagat ttcattaaaa agaaactgta tagagcaaaa
    49081 tctccacctt caggtttgaa agcggagatt gtttttattt tttcaaggtt tgtagtcgtg
    49141 gaacaatggc tagggttaga attgcagaaa tgaccaattc agcaattgaa tttgttgaga
    49201 taacggttgc cagaagaagt tggatatttc cattataaac atttccaaat aggaagaaga
    49261 ttcctccaag gacaaagata gtatttgtca aggaaccaag ggctccagct aaaatcagac
    49321 cagtcttgtt tttcatcagt ttatagacta agtaaggagt taaaccaatc aaaatacgtg
    49381 ggacgatggc aatgatagct gagtagatgt ttccgtttgg tacgaaggga gagaagaggt
    49441 agcttgtcgg tagaatcgta atcgtgttaa ccgtcaagct aagtaatccc atcaaaaatc
    49501 caagtgtaac cccaactcgt ggaccataaa taatgctggc aataatgaca ggaatatgaa
    49561 caatggtcgg tttgattgga aatggaaaaa ggttaaagat aagtgagctc agaaagtgta
    49621 tcacgagcat ggtagcaaaa aagatagcaa tgggtgcaat attagagcgt tttttcatcg
    49681 atagtttcct ttattctttc taaaataatt gtgaggtcag ctaaagctcc tcgtccgtgg
    49741 tctccacaag ctagtaggga ttccttagga gcaatcagct gatagccgta ggtttctaat
    49801 gttttcagat tattctgagt tactggatgg tcatacattt ttgtattcat agcaggagct
    49861 attagtttgg gaatatgact tggtagggct agagctgtac tggttaccat gttgtccgca
    49921 aatccgtgag ctagttttgc aatagtgtta gcagttgcag gtaccacgat aaataaatct
    49981 gctttttttc caagttcgat atgattgacc tgatcaggat agggttcctt catgacatcc
    50041 aagtggacag gattctgtga gagtacctgt agtgtcaaag gttggataaa ctctgtagca
    50101 gcctgagtca ttaagacagt gacttgatgg ccttgttttt ttagagaact gactaaatct
    50161 gccgacttat aagaggcgat tgaacccgtt acagccaaga gaatgtttgc catagttttc
    50221 ctttctaaga atgataggct tgaatttttt caaggaggag ttctgcaatt tcttctttag
    50281 tctggactgt ttgaagctga tttttctcaa caaatatagc tcggtgctga tctgctgaaa
    50341 tttgagtcag gtcattcgcg atgattaaat ctgcttgatt cttgataaga ctttttcgtg
    50401 caatgtcaac cagatgatct tcggtaacat caaccagcag tttgaaacca atcagatgaa
    50461 tagtgggatt ccattccttg actagggata tgattttggg tgtcttttta aggaacaaaa
    50521 cctgaacctc atcagttgaa gaaatcttgg cctgatgatt ctgcttgctt aaaaattctt
    50581 ttagattgga gctagcctga acttcctcaa gccctgtcat ataaacagga gtgtagtcag
    50641 aaacagccat tgagtggatc aagacctgat aatcctgaac acgttcttgc atttctatta
    50701 gaaggtcctt ggtattggta atttctcgaa tacttaggtt aggatgaggc tctggcttca
    50761 gagctcgttt tgtcgtaatt aaacaaactt catgccctgc agaaagcaaa gtctctgtga
    50821 taattttccc caagtgacct gtagaatggt tagtgataga gcggacgcta tcgatagctt
    50881 cactggtacc gcccgatgta actaaaattt tcatagcact attgtacaca aaaataagcg
    50941 gtaagtaaaa tgaaagtgat aaatttttgg taaaaacgaa gatttactat agtttcaaac
    51001 tataaagcca tataaaattt aagaaaggac tctaaaagcc ttaaaaacag agatatttac
    51061 gaacgtttag agagttttag gatgttaaaa atcttgtttt gtgatataat gaattatcat
    51121 ataagaggtt agaggaattt tgaatgaaaa cagatattga aatcgcacag agtattgagt
    51181 tgaagccaat tgttgatgtt gtagagaaac ttggtatttc ttatgacgat ttggagttgt
    51241 acggaaagta caaggctaaa ctcagctttg ataaaattcg tgcagttgag agcaatccag
    51301 tcggtaaatt gatcttggtt actgccatca acccaacacc tgcaggtgaa ggaaagtcga
    51361 cgcttaccat tggtcttgcg gatgccttga acaagattgg caagaaaacc atgattgcta
    51421 tccgcgaacc gtctcttggt ccagtcatgg ggatcaaggg tggtgctgct ggtggtgggt
    51481 atgcacaagt tctgccaatg gaagacatca acctccactt tactggagat atgcatgcta
    51541 ttacaactgc caacaatgcc ctttctgcct tgattgacaa ccacttgcac caagggaatg
    51601 agctggaaat tgatcaacgt cgtatcctct ggaaacgcgt tgtggacttg aacgaccgtg
    51661 cgctccgcca tgtgactgtt ggtcttggtg gtcctctaaa cggtattcca cgtgaggatg
    51721 gttttgatat tacagttgct tcagaaatca tggcaattct ttgcttggca acggacatcg
    51781 aggacttgaa acgtcgtttg gcgaatatcg ttattggtta tcgctatgac cgtacgcctg
    51841 tttctgtagg tgatttgcag gttgagggtg ccttggcttt gattttgaag gatgctatta
    51901 agccaaactt ggttcagaca atttacggta cacctgcctt tgtacacggt ggtccatttg
    51961 ccaatatcgc tcatggctgt aactctgttt tggcgacgac aacagccctt cacttggctg
    52021 attacactgt tactgaagct ggttttggtg cggaccttgg tgctgagaaa ttccttgata
    52081 tcaagacacc aaacttgcca acatctccag atgcagttgt cattgtcgca acccttcgtg
    52141 cccttaagat gaatggtggt gtggctaaag acgctctgac tgaagaaaat gtagaggcag
    52201 ttcgtgcagg ttttgctaac ttgaaacgcc acgttgaaaa tatccgtaag ttcggtattc
    52261 cagcagttgt agctattaac gaatttgtat ctgatacaga agctgaaatt gcagtcttaa
    52321 aagaactctg tgcctcaatc tatgtaccag ttgaattggc tagtgtctgg gctgatggag
    52381 cagaaggtgg agtagcactt gccgaaacag ttgttaagac aattgctgaa aatccagcta
    52441 actataaacg tttgtacgat aatgcccttt ctgtccaaga aaagattgaa aaaattgtca
    52501 ctgaaatcta tcgtggtagc aaagtgaact ttgagaagaa agctcaaaca caaattgctc
    52561 aaatcgttca aaacggttgg gacaaattgc caatctgtat ggctaaaact caatacagtt
    52621 tctcagacaa tccaaatgcg cttggagcac cagaaaactt tgaaattacc attcgtgaat
    52681 tggtaccaaa attaggtgca ggcttcatcg ttgccttaac tggtgatgtt atgaccatgc
    52741 caggtcttcc aaaacgtcca gcagctctca acatggatgt tgaaagcgat ggaactgtac
    52801 taggcttgtt ctagtggatt gaaattgact ttaagtgagt ttggaaataa tatccaagct
    52861 cattttttct cagactgcaa gcagttcatc aataagattt atactcttcg aaaatctctt
    52921 caaactacgt cagcttcacc ttgccgtagg tatatgatac tgactctgtc agttctatcc
    52981 acaacctcaa aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
    53041 ttcattgagt ataagtagat agaaaagtta tatactatct attgaaaata ttataaatca
    53101 gatacaaaga caggtgaaac cttctgtgtt atactagaga tatgttagat ttgaaagaat
    53161 acggtatcgt catgtggccg gaggagaaag tcatttcttt ccgtgagaaa cttctcgctt
    53221 ggtatgatga aaacaaaaga gatttgcctt ggaggagaag taaaaatcct tatcacatct
    53281 gggtatctga aatcatgctt cagcagacca gggtggatac agttatccct tactacgaaa
    53341 gattcctgga ctggtttcca actgtcgaaa gtctggcaac tgcgcctgag gagagtttac
    53401 tgaaagcttg ggagggcttg ggctattatt ctcgagttcg caatatgcag gctgcagccc
    53461 agcagattat gactgacttt ggtggccaat ttccaaatac ctatgaagga atttccagct
    53521 tgaaagggat tggaccttac acagcaggag ccatttccag tattgctttt aacttgcctg
    53581 agccagctgt agatggtaat gtcatgcggg tcttggcgcg tctgtttgaa gtcaaccacg
    53641 atattgggat tccaagtaat cgaaaaattt ttcaggcaat gatggagatc ttgattaatc
    53701 cggatcgtcc gggtgatttt aatcaagcct tgatggactt agggtctgat attgagtctc
    53761 ctgtaaatcc cagacctgaa gaaagcccag tcaaggactt tagtgcggca tatcagaatg
    53821 gaaccatgga ccgttatcca attaaatctc ctaagaaaaa gccggttcct atttatctta
    53881 aagccttagt tgtgaaaaat tctcaaggac aatttttact tgaaaaaaat gaaagcgaaa
    53941 agctcttggc aggtttttgg catttcccct ttatagaagt tgataacttt tcgcaagaag
    54001 agcagtttga cctctttcat caggttgcgg aagaaagtgt gaactttggc cccagtccag
    54061 aagagagttt ccagcaggac tatgacctag atgttgattg gcttgatgtt tgttttgata
    54121 cagtccagca tgtttttagt catcgaaaat ggcatgtaca gattgtagca ggtcaggtga
    54181 gtgacttcca tgatttttca gatagggaag ttcgttggct ttcaccagaa gaattcaaga
    54241 attacccact tgccaaaccc caacaaaaaa tctggcaggc ttatgcacaa gccaacttag
    54301 acagtagcca agactagcta ttgtgtcttc tgactatttt ttggtataat agtagagaaa
    54361 aaggtgaaca tatgaaaaaa atactaattg tagatgatga gaaaccaatc tcggatatta
    54421 tcaagtttaa tatgaccaag gaaggttacg aagttgtaac tgcttttaat ggtcgtgaag
    54481 cgctagagca atttgaagca gagcaaccag atattattat tctggatttg atgcttccag
    54541 aaattgatgg tttagaagtt gctaagacca ttcgtaagac aagcagtgtg cccattctta
    54601 tgctttcagc caaagatagt gaatttgata aggttatcgg tttggaactt ggggcagatg
    54661 actatgtaac gaaacccttc tccaatcgtg agttgcaggc gcgtgttaaa gctcttctgc
    54721 gtcgttctca acctatgcca gtagatggtc aggaagcaga tagtaaacct caacctatcc
    54781 aaattgggga tttagaaatt gttccagacg cctacgtggc taaaaaatat ggcgaagaac
    54841 tagacttaac ccatcgtgaa tttgagcttt tgtatcattt agcatcgcat acaggtcaag
    54901 tcatcacgcg cgaacacttg cttgagactg tctggggtta tgactatttt ggtgatgtcc
    54961 gtacagttga tgtgactgta cgacgtctgc gtgagaagat tgaagatacg cccagccgac
    55021 cagagtatat cttgacgcgc cgtggtgtag ggtattacat gagaaataat gcttgattta
    55081 ctgaaacaaa ccatttttac cagagatttt atctttatcc tgattttgtt aggtttcatc
    55141 cttgttgtga ccctcttatt actggaaaat agacgtgata atattcagtt gaagcaaatc
    55201 aatcaaaagg ttaaagattt gattgcagga gattattcca aggttcttga tatgcaaggt
    55261 gggtctgaaa tcaccaatat taccaataat ttgaatgact tgtcggaggt tattcgtctc
    55321 actcaggaaa atctagaaca agagagtaag aggctaaata gtattctgtt ttatatgaca
    55381 gatggggttc ttgcgaccaa ccgtcggggt cagattatca tgattaacga tacagccaag
    55441 aagcaactgg ggttggttaa ggaagatgtt ctgaatagaa gcattttgga attgctcaag
    55501 atagaagaaa actatgaatt gcgtgatttg attacccaaa gtccagaatt gttgctagat
    55561 tcccaagata tcaatggcga atatttgaac cttcgagttc gctttgcctt gatacgtcga
    55621 gagtctggct ttatttcagg tttggtggct gttttgcatg atacgacgga gcaggagaag
    55681 gaagaacgcg aacgaagact ctttgtttcc aatgttagcc atgagttacg gactcctctg
    55741 actagcgtaa aatcctatct tgaagccttg gatgaggggg ctttgtgtga aactgtagca
    55801 ccagacttta tcaaggtttc tcttgatgag accaaccgta tgatgcgcat ggtgacggat
    55861 ctcctccatc tttcacgtat tgataatgct accagtcacc tagatgtgga actgattaac
    55921 ttcactgctt ttattacctt tatcctcaat cgttttgaca agatgaaagg acaggaaaag
    55981 gagaaaaaat atgagttggt gagagattat cccatcaatt ctatctggat ggaaattgat
    56041 acagataaga tgacgcaggt tgtcgacaat attttaaata atgctattaa gtattcgcca
    56101 gatgggggta aaatcactgt cagaatgaag acaactgaag accagatgat tttatccatt
    56161 tctgaccacg gtttggggat tcctaagcag gatttaccac gtatctttga ccgtttctat
    56221 cgtgtggatc gtgctagaag tcgtgcacaa ggtggtacag gtctaggact gtctatcgct
    56281 aaagaaatta tcaaacaaca taagggcttt atttgggcca agagtgaata cggcaagggt
    56341 tcaaccttta ccattgtgct cccttatgat aaggatgcag tgaaagaaga agtatgggag
    56401 gatgaagtag aagactagaa tgagtgaaat aggctttaaa tacagtattt tagcgtcggg
    56461 ttccagtgga aattcttttt atctggaaac ctcaaaaaag aagcttttag tagatgcagg
    56521 cttgtctggc aagaaaatta ccagtctgct agctgaaatt aaccgtaagc cagaagacct
    56581 ggatgccatc ttgattaccc atgagcattc agatcatatc catggagtag gcgttttggc
    56641 tcgcaagtat ggtatggatc tttatgccaa tgaaaagacc tggcaagcta tggaaaatag
    56701 taaatatctt ggcaaggtgg attcttcgca aaagcatatt tttgaaatgg gtaaaaccaa
    56761 aacctttgga gatatcgaca tcgagagttt tggtgtaagc catgatgcag tcgcaccgca
    56821 gttctatcgc tttatgaagg atgataagag ttttgtcctt ttgacagata caggttatgt
    56881 cagtgaccgt atggcgggca ttgtcgaaaa tgcggatggc tatcttatcg aggccaacca
    56941 tgatgtagag attttgcgat caggttctta cgcttggcga ctcaaacaac gaatcctatc
    57001 tgaccttggt cacctttcta acgaggacgg tgctgaagct atgattcgga cgctaggaaa
    57061 tcgtactaag aagatttacc ttgggcattt atctaaggaa aataatatca aggaactggc
    57121 tcatatgacc atggtcaatc agctggctca agctgatctg ggagtcggag tagactttaa
    57181 ggtttatgat acctcaccag ataccgcaac accattgaca gagatataga aagaacgctg
    57241 agaaggtgtt ctttttatat tgactgaaca cctaaaaagt aatacaatgg tgttaccatt
    57301 aaaaaaggga gcacaaaaga tgactactat tacattaaaa gtttctgaag ctgataaaac
    57361 atttatgaaa gcaatggcta agtttgaagg agtttccctt tcggaactta ttcgcaccaa
    57421 aactcttgaa gccctagaag atgaatacga tgctcgtgtg gcagatttag cctatcaaga
    57481 gtatttagaa gacttggaaa aaggagttga acccattact tgggaagaaa tgatgcatga
    57541 tttaggcttg aaggatgaat aatttgtata aattagttcc aacaagacgt tttatcaagc
    57601 aattgaaaaa attggaccgt tatacgcaga agctaattac aaactattta caaaccaatg
    57661 ttttggaagg tccaagacga cacggaaagg ctttggttgg taatcgcgtt ggtcaatggc
    57721 gctatagaat tggtaattat cgagttatcg tacaaattgt agatgatgaa ttagtcgttg
    57781 ctactctaga agttggtcat cggagagata tttattgaat taaagctgag taataacaat
    57841 atagaaagta aggagagtaa aaatttgaag aaaaaatggt tatttgcaga ttattatgat
    57901 acaacaatta ttttacttgc tttaatctct gttattctgg tattacttgg atttgctgag
    57961 atgactgatt tggacaatcc gccttatagt attattgatt tagtaatctg gggtgttttt
    58021 gtaattgatt atagttggcg cttttttatt actaaaagaa aatggcgctt tattcttgaa
    58081 aatatttttg atttattgac cattctccct ttaaatgcta tttttacagt gtttcgatta
    58141 ggacgtatct tccgcttagc aaggctgaca aaattactga aactgactcg tttacttaga
    58201 ataattggac ttacaggtaa actagaaaga aaaattagta gattcttacg aacaaatgga
    58261 ttgatttata tcttgtatgt taatatcttt attgttctag tagggagttc gattttatcc
    58321 gttgttgaag aaaaatcctt ctcagatagt ctttggtggg ctcttgtgac agtaactact
    58381 gttggttatg gtgatattgt tccagtttcc ctttttggga aatggctagc agttttactg
    58441 atgcttgtcg gtattggaac aatagggatg ctaacaagtg ctttgacgaa cttttttgta
    58501 aaggataatc cagatgaaca gataaaactt gataaactca aagacgaatt atcgagctaa
    58561 agaatattaa tagagaaaca atctgaaaaa atcgaagaac tacattgaat gataaaagac
    58621 ttagttgaaa aaatatcata aaggtgagac aaaataaaac ttgattcgag gagaaatcaa
    58681 gtaagttttg acacaataga acgcatatta tcaggtataa aaacttgata ctatgcgttt
    58741 tatagagaaa taaaataaaa tctgaacaaa tcaattagga atttaaagca ttttataaca
    58801 acgttttaga gtaatggggt gctatttcaa cttcaaccta ctataataca gaaaaaaata
    58861 cagaaaaaaa caactccctg atgattcaag gagttgtcta tagttaaatt agtttttaga
    58921 agcttcttgg aattctggat ttttccatgc ttcgtcaata atagcttgca attctttagc
    58981 agatgcttgc attttttgag tttctgcatc gttcaatgga atgtttactg gacgaacgat
    59041 accatgtgca ccaacaacag ctggttgacc gataaagaca ttctcaactc cgtattgacc
    59101 ttcttggaat actgaaagtg gaagtactgc gttttcatcg tcaaggattg ctttagtgat
    59161 acgagcaagg gctactgcga taccgtagta tgttgcacct tttttgttga tgattgtgta
    59221 ggctgcatca cgaacacctt cgaacaattc aatcaattca gcttcttgaa cattttgagt
    59281 gtctttaagg aattcttcaa ggtttacacc agcgatgtta gcgtgtgacc aaacagcgaa
    59341 ctcagagtca ccgtgttcac ccatgatgta ggcgtgcact gaacgagcat ccacatccaa
    59401 tttttcagca agtgcttgac ggaaacgagc tgagtcaagt gaagtacctg aaccgataac
    59461 gcgttcttta gggaaaccag agaatttcca agttgagtaa gtcaaaacgt caactgggtt
    59521 agcagcaaca aggaagatac ctttgaaacc agattcaaca acttgagtta cgattgattt
    59581 gttgatagca aggtttttac ctacaaggtc aagacgagtt tcacctggtt tttgaggtgc
    59641 acctgcagtg atcacaacaa ggtcagcgtc tgcacagtca gagtattgag ctgcatagat
    59701 ttttttaggt gaagtgaagg caagggcgtg actaaggtca agcgcatcac caacagcttt
    59761 ttcatgcaat tgtggaattt cgataattcc aagctcttgt gcaattcctt ggttaacaag
    59821 tgcaaaagcg taagatgaac ctacagcacc atcaccgaca aggataactt ttttgtgttg
    59881 tttagttgaa gtcattgttt taaacatctc cttaatttta ttaggggatt ttccctagac
    59941 aacttcattc tatcactttt aaaaaacttt gtcacgaata tgccttatag ttctcgatgt
    60001 aaacgtttta gtggtttaga ggctgaaata gatgggaatt tatggtataa tgttgttact
    60061 tactaattgt gaaatgaggc atttattaat gcaggataaa aatttagtga atgtcaatct
    60121 gacaaaggag atgaaggcaa gttttatcga ctacgccatg agtgttatcg tagcgcgagc
    60181 tcttcctgat gttcgagatg gcttaaaacc tgttcaccgt cgcattctct acggaatgaa
    60241 tgaattgggt gtgaccccag acaaacccca taaaaaatct gctcgtatta caggggatgt
    60301 catgggtaaa tatcacccac acggggattc ctctatttat gaagccatgg tccgtatggc
    60361 tcaatggtgg agctaccgtt acatgcttgt agatggtcat gggaattttg gttccatgga
    60421 tggagatagt gctgccgctc aacgttatac cgaggcacgt atgagcaaga ttgctctgga
    60481 aatgcttcgt gatatcaaca aaaatacagt tgatttcgtt gataactatg atgccaatga
    60541 acgggaaccc ttggtcttgc cagcgcgttt tccaaacctt ttggttaatg gagcaactgg
    60601 tatcgcggtt gggatggcaa ccaatattcc acctcataat ctgggtgaaa ccattgatgc
    60661 agtgaagttg gtcatggata atcctgaagt gactaccaag gacttgatgg aagtcttgcc
    60721 tggaccagat tttccaactg gtgctcttgt catggggaaa tcaggtatcc ataaggctta
    60781 tgaaacaggt aaaggttcga ttgtcctacg ttctcgtaca gagattgaaa cgactaagac
    60841 tggtcgtgag cgtatcgttg taacagaatt tccttacatg gtcaataaaa ccaaggtgca
    60901 tgagcatatt gttcgcttgg ttcaggaaaa acgcattgag ggtatcacag cagtacgtga
    60961 tgagtcaaac cgtgaaggtg ttcgatttgt tattgaagtc aagcgcgacg cctcagccaa
    61021 tgttattctc aataacctct tcaaaatgac ccaaatgcaa accaattttg gattcaatat
    61081 gctcgctatc caaaatggta taccgaaaat tttgtctctt cgtcagattt tggatgctta
    61141 tattgagcac caaaaagaag tggttgttcg tcgtacacgt tttgataagg aaaaagcgga
    61201 agcgcgcgct catatcttag aaggtctctt gattgcgcta gaccatatcg acgaagtgat
    61261 tcgtatcatc cgtgctagtg aaacggatgc ggaagctcaa gctgagttga tgagcaagtt
    61321 taagctttct gaacgtcaaa gtcaagctat ccttgatatg cgtcttcgtc gtttgacagg
    61381 tttggaacgc gataagattc aatctgagta tgatgacctc ttggctctga ttgcggattt
    61441 agcagatatt cttgctaagc ctgaacgtgt ttctcaaatt atcaaagacg aattggatga
    61501 agttaaacgt aaattttctg ataaacgccg tacagagttg atggttggac agatcttgag
    61561 tctcgaggat gaggacttga ttgaagaatc ggatgtcttg attacccttt ctaacagagg
    61621 ctacattaag cgtttggatc aggacgagtt cactgctcaa aaacgtgggg gtcgtggtgt
    61681 ccaaggaacg ggagtgaaag atgatgactt tgttcgtgag ttagtgtcaa ctagcaccca
    61741 tgatcatctg ctcttcttca caaacaaggg acgtgtctat cgtcttaaag gttatgaaat
    61801 tcctgagtat ggtcggactg ccaaagggct accagtagtc aatctcttga aattggatga
    61861 agatgaaagt attcagacgg ttatcaatgt tgagtctgat cgcagtgatg atgcttatct
    61921 cttctttaca acccgtcacg gtattgtgaa gagaactagt gttaaggagt ttgccaatat
    61981 tcgtcaaaat ggtctcaaag cgctgaattt aaaggatgaa gatgagttaa tcaatgtctt
    62041 gttgacagaa ggagatatgg atattatcat tggtaccaag tttggttatg cagttcgctt
    62101 taatcaatca gccgttcgtg gtatgagccg tatcgccact ggtgtgaaag gtgttaacct
    62161 tcgtgaagga gacacagttg ttggtgccag cttgattact gatcaagatg aggttcttat
    62221 tatcacagaa aaaggatatg gtaagcgtac agtcgctact gaatacccaa caaaaggtcg
    62281 tggtggtaag ggaatgcaga cagctaaaat taccgaaaaa aatggcttgc tggccggtct
    62341 tatgactgtt caaggggatg aggatttgat gattatcact gatacaggtg tcatgattcg
    62401 aaccaatctt gccaatattt cacaaacagg acgtgcaact atgggagtta aagtaatgcg
    62461 cctggatcaa gatgctcaga tagtgacttt cacaacggtt gcggtggcag aaaaagaaga
    62521 agttgggaca gaaaacgaaa cagaaggtga agcataatgt ctcaaaaaaa taataaaaag
    62581 aaaaacaagc gaaaaaatct gctgacaaat atcctagcag gatttctgat attactgtca
    62641 ctggctttga tttttaatac tcaaattcga aatattttca tagtctggaa taccaataag
    62701 tatcaagtta gccaggtatc aaaagaaaaa ttagaagaaa atcaggatac agaaggcaat
    62761 tttgactttg attctgtcaa agctatctct tcggaagctg ttctaacttc tcaatgggat
    62821 gctcaaaaat taccagttat tgggggaatt gcaattcctg aattggaaat gaatttgccg
    62881 atttttaaag gacttgataa tgttaatctc ttctacggag ctggtacaat gaaacgcgag
    62941 caagtaatgg gagaaggaaa ttatagtcta gctagtcacc atatctttgg tgttgataat
    63001 gctaataaaa tgttattttc tcctttagat aatgctaaaa atggcatgaa gatttatcta
    63061 accgataaaa ataaagttta tacttatgaa atacgtgaag tcaaacgtgt gacaccggat
    63121 cgtgttgatg aagttgatga tagagatggg gtcaatgaaa tcacattagt aacctgtgaa
    63181 gaccttgctg ctacagaacg tattattgtc aaaggtgatt tgaaagaaac aaaagattat
    63241 tcacaaacat ctgatgaaat tctaacagct ttcaatcaac catataaaca attttattaa
    63301 tacaaatcag tgaaatcatg gatttcactg attttttaag attttcataa aaatatagta
    63361 aaatgaaata agaataggac gaatcgttca ggacagtcaa atcga
//
LOCUS       DBERCW010000008        61753 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.008, whole genome shotgun sequence.
ACCESSION   DBERCW010000008 DBERCW010000000
VERSION     DBERCW010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 61753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61753
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.008"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(779..1039)
                     /locus_tag="ACL72M_000648"
     CDS             complement(779..1039)
                     /locus_tag="ACL72M_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715817.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(1098..1649)
                     /locus_tag="ACL72M_000649"
     CDS             complement(1098..1649)
                     /locus_tag="ACL72M_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715818.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNIFVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1639..2634)
                     /locus_tag="ACL72M_000650"
     CDS             complement(1639..2634)
                     /locus_tag="ACL72M_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715819.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(3042..3467)
                     /locus_tag="ACL72M_000651"
     CDS             complement(3042..3467)
                     /locus_tag="ACL72M_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715820.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3611..3955)
                     /locus_tag="ACL72M_000652"
     CDS             complement(3611..3955)
                     /locus_tag="ACL72M_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGS0715821.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKK"
     gene            complement(4001..4207)
                     /locus_tag="ACL72M_000653"
     CDS             complement(4001..4207)
                     /locus_tag="ACL72M_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715822.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(4194..4355)
                     /locus_tag="ACL72M_000654"
     CDS             complement(4194..4355)
                     /locus_tag="ACL72M_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0715823.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4714..5670)
                     /gene="lytA"
                     /locus_tag="ACL72M_000655"
     CDS             complement(4714..5670)
                     /gene="lytA"
                     /locus_tag="ACL72M_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGS0715824.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(6046..7416)
                     /locus_tag="ACL72M_000656"
     CDS             complement(6046..7416)
                     /locus_tag="ACL72M_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS0715825.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(7723..8889)
                     /gene="recA"
                     /locus_tag="ACL72M_000657"
     CDS             complement(7723..8889)
                     /gene="recA"
                     /locus_tag="ACL72M_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGS0715826.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(8944..10200)
                     /locus_tag="ACL72M_000658"
     CDS             complement(8944..10200)
                     /locus_tag="ACL72M_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGS0715827.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(10285..11301)
                     /locus_tag="ACL72M_000659"
     CDS             complement(10285..11301)
                     /locus_tag="ACL72M_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGS0715828.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(11309..11827)
                     /locus_tag="ACL72M_000660"
     CDS             complement(11309..11827)
                     /locus_tag="ACL72M_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS0715829.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGELFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(11817..12260)
                     /gene="tsaE"
                     /locus_tag="ACL72M_000661"
     CDS             complement(11817..12260)
                     /gene="tsaE"
                     /locus_tag="ACL72M_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGS0715830.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(12346..12966)
                     /locus_tag="ACL72M_000662"
     CDS             complement(12346..12966)
                     /locus_tag="ACL72M_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715831.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTVFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(13349..14212)
                     /locus_tag="ACL72M_000663"
     CDS             complement(13349..14212)
                     /locus_tag="ACL72M_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0715832.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            14404..14526
                     /locus_tag="ACL72M_000664"
                     /pseudo
     CDS             14404..14526
                     /locus_tag="ACL72M_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
     gene            14677..14901
                     /gene="pneA1"
                     /locus_tag="ACL72M_000665"
     CDS             14677..14901
                     /gene="pneA1"
                     /locus_tag="ACL72M_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HGS0715833.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            14908..15096
                     /gene="pneA2"
                     /locus_tag="ACL72M_000666"
     CDS             14908..15096
                     /gene="pneA2"
                     /locus_tag="ACL72M_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HGS0715834.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            15331..18201
                     /gene="lanM"
                     /locus_tag="ACL72M_000667"
     CDS             15331..18201
                     /gene="lanM"
                     /locus_tag="ACL72M_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="HGS0715835.1"
                     /translation="MSIISEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAK
                     NSEWYKFAEGSFEIFRKHPQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKN
                     GNIFSSLVFYLEDLIYPWIVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENI
                     LNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGD
                     THSQGKTVLILFFDDAKIVYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDH
                     SYEEFIDYLPLEQKKKLPEYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFET
                     MLQQPLFDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNG
                     QVLINLNTDKVKFDIGKIDFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNK
                     TEEFKMLLKANLYGLKTRVLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKF
                     SNQGIVASECEQMRLLDIPIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNN
                     LENLEKQLDIIEIYFPSFDQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVIN
                     NIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNK
                     MLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFA
                     SVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYS
                     FGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQS
                     VPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIV
                     QTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLLEI"
     gene            18551..19255
                     /locus_tag="ACL72M_000668"
     CDS             18551..19255
                     /locus_tag="ACL72M_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGS0715836.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            19236..20165
                     /locus_tag="ACL72M_000669"
     CDS             19236..20165
                     /locus_tag="ACL72M_000669"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HGS0715837.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            20162..22270
                     /locus_tag="ACL72M_000670"
     CDS             20162..22270
                     /locus_tag="ACL72M_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGS0715838.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            22294..24033
                     /locus_tag="ACL72M_000671"
     CDS             22294..24033
                     /locus_tag="ACL72M_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS0715839.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            24084..24851
                     /locus_tag="ACL72M_000672"
     CDS             24084..24851
                     /locus_tag="ACL72M_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGS0715840.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            24853..25485
                     /locus_tag="ACL72M_000673"
     CDS             24853..25485
                     /locus_tag="ACL72M_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715841.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(26414..26827)
                     /gene="ndk"
                     /locus_tag="ACL72M_000674"
     CDS             complement(26414..26827)
                     /gene="ndk"
                     /locus_tag="ACL72M_000674"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGS0715842.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(26938..30615)
                     /gene="rpoC"
                     /locus_tag="ACL72M_000675"
     CDS             complement(26938..30615)
                     /gene="rpoC"
                     /locus_tag="ACL72M_000675"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGS0715843.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(30648..34259)
                     /gene="rpoB"
                     /locus_tag="ACL72M_000676"
     CDS             complement(30648..34259)
                     /gene="rpoB"
                     /locus_tag="ACL72M_000676"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS0715844.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            34675..34745
                     /locus_tag="ACL72M_000677"
     tRNA            34675..34745
                     /locus_tag="ACL72M_000677"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34707..34709,aa:Cys,seq:gca)
     gene            complement(34943..36274)
                     /locus_tag="ACL72M_000678"
     CDS             complement(34943..36274)
                     /locus_tag="ACL72M_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGS0715845.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRIAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(36503..37327)
                     /gene="endA"
                     /locus_tag="ACL72M_000679"
     CDS             complement(36503..37327)
                     /gene="endA"
                     /locus_tag="ACL72M_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGS0715846.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(37366..37554)
                     /locus_tag="ACL72M_000680"
     CDS             complement(37366..37554)
                     /locus_tag="ACL72M_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS0715847.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(37547..38830)
                     /gene="murA"
                     /locus_tag="ACL72M_000681"
     CDS             complement(37547..38830)
                     /gene="murA"
                     /locus_tag="ACL72M_000681"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS0715848.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(38854..39084)
                     /locus_tag="ACL72M_000682"
     CDS             complement(38854..39084)
                     /locus_tag="ACL72M_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGS0715849.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(39142..40179)
                     /locus_tag="ACL72M_000683"
     CDS             complement(39142..40179)
                     /locus_tag="ACL72M_000683"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGS0715850.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(40163..40651)
                     /gene="coaD"
                     /locus_tag="ACL72M_000684"
     CDS             complement(40163..40651)
                     /gene="coaD"
                     /locus_tag="ACL72M_000684"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGS0715851.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGRDIACYVPESILEEIRNEK
                     KD"
     gene            complement(40641..41180)
                     /gene="rsmD"
                     /locus_tag="ACL72M_000685"
     CDS             complement(40641..41180)
                     /gene="rsmD"
                     /locus_tag="ACL72M_000685"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGS0715852.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(41245..42237)
                     /gene="asnA"
                     /locus_tag="ACL72M_000686"
     CDS             complement(41245..42237)
                     /gene="asnA"
                     /locus_tag="ACL72M_000686"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGS0715853.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(42350..43033)
                     /locus_tag="ACL72M_000687"
     CDS             complement(42350..43033)
                     /locus_tag="ACL72M_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGS0715854.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(43089..43829)
                     /locus_tag="ACL72M_000688"
     CDS             complement(43089..43829)
                     /locus_tag="ACL72M_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGS0715855.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            43863..44141
                     /locus_tag="ACL72M_000689"
     CDS             43863..44141
                     /locus_tag="ACL72M_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGS0715856.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            44219..45145
                     /gene="yidC"
                     /locus_tag="ACL72M_000690"
     CDS             44219..45145
                     /gene="yidC"
                     /locus_tag="ACL72M_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS0715857.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(45220..46014)
                     /gene="pflA"
                     /locus_tag="ACL72M_000691"
     CDS             complement(45220..46014)
                     /gene="pflA"
                     /locus_tag="ACL72M_000691"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGS0715858.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(46140..47390)
                     /locus_tag="ACL72M_000692"
     CDS             complement(46140..47390)
                     /locus_tag="ACL72M_000692"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGS0715859.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(47457..48284)
                     /gene="purR"
                     /locus_tag="ACL72M_000693"
     CDS             complement(47457..48284)
                     /gene="purR"
                     /locus_tag="ACL72M_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGS0715860.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(48551..49492)
                     /locus_tag="ACL72M_000694"
     CDS             complement(48551..49492)
                     /locus_tag="ACL72M_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGS0715861.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(49482..50738)
                     /gene="rmuC"
                     /locus_tag="ACL72M_000695"
     CDS             complement(49482..50738)
                     /gene="rmuC"
                     /locus_tag="ACL72M_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGS0715862.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(50740..51402)
                     /locus_tag="ACL72M_000696"
     CDS             complement(50740..51402)
                     /locus_tag="ACL72M_000696"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGS0715863.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(51365..52021)
                     /gene="rpe"
                     /locus_tag="ACL72M_000697"
     CDS             complement(51365..52021)
                     /gene="rpe"
                     /locus_tag="ACL72M_000697"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGS0715864.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(52032..52910)
                     /gene="rsgA"
                     /locus_tag="ACL72M_000698"
     CDS             complement(52032..52910)
                     /gene="rsgA"
                     /locus_tag="ACL72M_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGS0715865.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(52912..53784)
                     /gene="rsmA"
                     /locus_tag="ACL72M_000699"
     CDS             complement(52912..53784)
                     /gene="rsmA"
                     /locus_tag="ACL72M_000699"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGS0715866.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALAEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(54035..54328)
                     /locus_tag="ACL72M_000700"
     CDS             complement(54035..54328)
                     /locus_tag="ACL72M_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715867.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(54321..54962)
                     /locus_tag="ACL72M_000701"
     CDS             complement(54321..54962)
                     /locus_tag="ACL72M_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715868.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(54964..56994)
                     /locus_tag="ACL72M_000702"
     CDS             complement(54964..56994)
                     /locus_tag="ACL72M_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS0715869.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     LGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(57071..57367)
                     /locus_tag="ACL72M_000703"
     CDS             complement(57071..57367)
                     /locus_tag="ACL72M_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS0715870.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(57687..58586)
                     /locus_tag="ACL72M_000704"
     CDS             complement(57687..58586)
                     /locus_tag="ACL72M_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0715871.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(58658..59218)
                     /gene="rnmV"
                     /locus_tag="ACL72M_000705"
     CDS             complement(58658..59218)
                     /gene="rnmV"
                     /locus_tag="ACL72M_000705"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGS0715872.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(59218..59991)
                     /locus_tag="ACL72M_000706"
     CDS             complement(59218..59991)
                     /locus_tag="ACL72M_000706"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGS0715873.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(60296..61189)
                     /locus_tag="ACL72M_000707"
     CDS             complement(60296..61189)
                     /locus_tag="ACL72M_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HGS0715874.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATLEY
                     KLETIPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(61473..61607)
                     /gene="rpmH"
                     /locus_tag="ACL72M_000708"
     CDS             complement(61473..61607)
                     /gene="rpmH"
                     /locus_tag="ACL72M_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGS0715875.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        18687 a        12893 c        11212 g        18961 t
ORIGIN      
        1 aactaggatt ctagttttgc aggaagtcta ttatatatat gcacagacat atgaaatctt
       61 tttgatacag ccttcttttt acatagagag acagcagtta tgatatattt atccattcac
      121 aaaatcttct gtaccaatac tacaataatt ggtacatttt gattacacaa tcgtttcaaa
      181 aaatatgatg gaagactgag tattttatag taattccctt cctatcaact agatcaacca
      241 gttgagtgtt gaatgttgaa acaccctagc ctcagcaaag gactatgatc agcatttcct
      301 agccaatagg acgctccaaa tcacctattc taagtccatc actagcttgg tcagtaagat
      361 acagactgca aggcaagact gacgtggttg atgagatttt ggaagagtat tacaatcata
      421 gattcaccag tagacttgac cgcagattta actatagtag attgaaacta gaatagtaca
      481 cttctgcttc taaaacattg ttagaaatcg atttgactgt cctgatcaat ttgtcctgtt
      541 ctcgtttcat tttactatac taaaaaacca cctgaaacaa atcaagtgac tagaggataa
      601 aaacaaagac tgggcaaaaa gttttgaaaa gcaaaaaacg cataatatca ggtcttgaaa
      661 aaccttgcta ctatacgttt gattgtggga agattgactt cattttctcc tgaaattgaa
      721 gttttttcta gtttccaggt atagacgaat tcaatatagc catctcgcta caattatttt
      781 aaccatcgaa aaaatttttc agaatttcaa aaatttcatt ttgatccaat gaaatgtcat
      841 tattttgaag aatagttgac ttcacaggct ctaattctat cacaaagcgg tgcatgtctg
      901 cttttaccgc actacttgat gttatagccg ataacttttc atctcctagc aaggaagctg
      961 tcaaacgggt aaggtcattc aaatgctttt taatggactt acttaaacct tgagcacctg
     1021 tggcagagcg ctccctcata tccagccaag ctttagcctt aaaaataatt aatactcaat
     1081 gaaaatcaaa gagcaaacta ggaagctagt tgcaggctgc tcaaaacact gttttgaggt
     1141 tgtagatgga agctgacgtg gtttgaagag attttcgaag agtatagacc acaattactc
     1201 aataccgaat acccctgaat ggtttctttt acatgcacaa atatattata ataatcttca
     1261 tccaataata aggctgataa actagcatct tggtcaaaat ataagggaat ttctcgaccg
     1321 tccttcttta atggatattc tggtaagata ctaaatagtt caatcataga aggaaactca
     1381 gaattagttg ttgtaaatcg aaaaagctgc gctttctcat ctttctgact tccttgatac
     1441 tctcccaatt ctaaaaaatg attcaaggta gtataaaatt ccttattttt tacttcatca
     1501 atgatgacca tatcataatc ttttgttgtg cgacttttaa atccttgcga atccaatacg
     1561 atagaggtag cagttccccc aatcagaaca taatagttct gaaaatccgc aaacatttct
     1621 tgaaaaataa ctttcgtatt agctggcatc atcttctccc agatactgta atatcatatt
     1681 ttctagtgct tcactctctt cctctatacg tgggtcatca tcatctttta aggtcaaata
     1741 aagagaaatc ggatctacaa attgtttatc atgattattt ttaaaatcat tccaaaactc
     1801 agatacaaaa ggacgatatt tccatatctc tagcatcttt ccttttaaaa tatgctgaga
     1861 aagtggcaag gataactgat tgaattttct ctgccatatg acatagctag tattttcatc
     1921 cgtttcagct aaaaaagttg aatgcgacaa agcataagca ccaccatata gaaggttaga
     1981 aacagatttt atctgcttta tatcgccatc tggcaataaa atccgttttt tgatgggatt
     2041 aaataaacat gacacggatt ttaagaataa ttctttcttt gacaccgtat atgtgtaaag
     2101 cttattttgc ttgtttaacc aatataaagc tttaaaagtc ctcaaacacc tataaattgt
     2161 tgagtttgga agtccagtga cttgtgaaag caaatcaaca tctactactt tttgaccttt
     2221 tgtcaataaa aaggcaatcc acgttaattg ttcgctaggt gttaattcct tagggacttc
     2281 agtatcattc gcattgagta ctagtcccaa tggagggaag aagaggtttc ccttaaagtc
     2341 tacaaacgga actctagctt gaagtaattg ctttttttca ctgtctgata acttcgaaaa
     2401 caccaaaaca acatccatat tggctttttc acccatagtg cgagcctgag taacaaatga
     2461 actcaaactc ccccttctct tttctttaat caataaaaat gattccttat gaaaagtcat
     2521 ttgagtatac tcaaaccttt ttacaaaact gattggtaaa gtcaaagtca gttcctcaat
     2581 actgacatca acataaaagg attgaaaaat tgacattatc tttttgacat tcatgttttt
     2641 tccttattct atcattttta ttatatttta tcattcggta taataaaata taagtttttt
     2701 gataaaataa ccaaaaacta ctccctatcc cctctcacat taccctacat atcgtttgac
     2761 atgcgactga tagttcagga aaacttcaag gagaactttt ctctcatcca ctatgcagga
     2821 cttactattt cacttctact cctataggct caatttgaca cttttctttt tcgaattgct
     2881 catatgcctc ctgaatagtg agttcgattt atccaaattt atttttgtct attttgatga
     2941 atacttccac gaagatagtc tgaaaatgaa tttgcaccaa ttttccttct ctttttaagc
     3001 atattattcc agatatgatt gccctcttgt tcagtaataa attacgcttt aaacgcttca
     3061 atcagtatat ctcctgttgt catatgttct aaagaaaatt cttctacata tgatttaaca
     3121 tctcttaggt tattacttcc taatatccca ttatgctttt tcgctaagga aatagaagcc
     3181 gcttctccct taccaataat cttgttacta tcatgatttc ttgttaaatc tctatataat
     3241 gcgtattctt cagttccaat gtctatgctc acaatctcag ctgaaccctt agctaccaac
     3301 tgatctatcc tagattttaa atggggaatt gtaggtatat tgatttcatc atacacctct
     3361 tgtggaataa caattttacc cgaatagagc ttttctaaaa gatgttcagt accaacccat
     3421 aaaaatactg aaatacaatc tgcatcaata aatacacgac tagtcaaacg acaactcccc
     3481 cctcttcatc tagcccatat acaatatcat atctgaaagc atctagtaac agttcctcat
     3541 acttcccttg cgaaattctg ttattttcta aaagttgttc agttgaatta acatattatc
     3601 ctaatatcat ttacttttta ctttctgaca aaggacgata taaacttgta tcatagccta
     3661 atcttgaagc tgtctctata acactaatat ccatattttt aatttcttct gcatcaaggt
     3721 atccatcatt cctcaatcta tataacataa ctttatgact gataccataa aactgaccca
     3781 attttataat atcttctact tcaagatgag ttctattggc attttctcta atttcctcaa
     3841 ccatcctata cagtgaagat gggaaaatta aaaaataaga agcaaactga tccgcttttc
     3901 tttcagtttc atctccttca ccaatcaaga taagactgac tgaactcttc ttcacctcat
     3961 cataataaag atgatacagt tcatgtgcta aagaaaatct ttaccttcct aatgacatgt
     4021 ctgaattgac tgcaatgaga ctgaactgag ttcctttata acagactccg ctaatattct
     4081 ttccgagtcc ataaaatacc agcgtcaaat tttctatctt ttgtaccaat ttaaaaatat
     4141 ctatcggcga ttcaccatca gctcccaact tttttctaag atttgaagct ttattactta
     4201 aatccattcg tgatattcct ttcacctttt tccattttgg caatcatgct ttgattcaaa
     4261 gacaaatact cagcaatctt atcttgagta agatttgaag atattctaag ttcttttatt
     4321 ctttttccaa catcacatac atttatcaca tacatttatc atattcatac acctctcata
     4381 aaaagaatag cacacttttg tcataatttt ttaaataaaa aaattatgac aaaacaagga
     4441 agcaatttat tgatgctgct taaaaatcta aaattgatga gttcctatca aaaatcgtat
     4501 cttcaacctc aaaacagtac ttaaagctat ccgactcggt ttacattgtc aaatttagat
     4561 tttatttgag cataactttc tagtttgctt tctgattttt gtttaatata gtagcaaaca
     4621 ttgaaggaaa tatctccaca aaaaaacgca tactattaag ctttttcaag acctaataat
     4681 atgcgctgtt ctgatttgaa agacattcca ttattatttt actgtaatca agccatctgg
     4741 ctctactgtg aattctggct tgtctgccag tgttccgtct ggtttgaggt agtaccagcc
     4801 tgttccgtcc gctgactgga taaaggcatt tgataccatg gcgccttctt tagcgtctaa
     4861 gtagtaccaa gtgtccttgt acttgaccca gcctgtcttc atggcacctt cttcgttgaa
     4921 atagtaccac ttatcagcga ttttcttcca gcctgtagcc atttcgcctg agttgtcgaa
     4981 ccagtaccag ttgccgtctg tgtgcttcct ccagcggtct gcaagcatat agcctgaact
     5041 gtcaaagtag taccaagtgc cattgatttt ctcaaacttg tcttttggat aagagccgtc
     5101 tgaatgtacg taccagtagc cagtgtcatt cttctgccag cctgtttcaa tcgtcaagcc
     5161 gttctcaata tcatacttaa actgctcacg gctaatgccc cattttgcca agtaagggta
     5221 tggatccaca tggtctgagt ggttgtttgg ttggttattc gtgcaatact cgtgcgtttt
     5281 aattccagct aaactccctg tatcaagcgt tttcggcaaa cctgcttcat ctgctagatt
     5341 gcgtaagagt tcgatataaa ggcggtagtc cgtcatgaac tcttctttag ttgaatggct
     5401 ttcaatcagt tcaaccgctg cataggtttc agcattccaa ccgcccccaa cgtcccaggc
     5461 accattatca acaggtccta cctgcatgat gcaaccgttc ccaacaatgt gcgagaaaaa
     5521 acctaattct gggtctttcc gccagtgata atccgcttca ttctgtacgg ttgaatgcgg
     5581 attcccagtt gagtgtgcgt gtacttgcct atatggttgc acgccgactt gaggcaaatc
     5641 tgttcttaat ttactcacat taatttccat attctactcc ttatcaatta aaacaactca
     5701 ttttttacaa tccagaacca gaaactcctt tatttctacc ttacaaagaa gacaatctta
     5761 gtcacgatta ggcttgtaga tagaacctca aaacgcacta ttttgacact gtaaatagga
     5821 ctgacaaggt ctgcattcta tctacaataa caccccagac taaaaagctt ttcaaaagta
     5881 tatttttaca gtctctatat gtccttttca taaatactat actttattat atcatataaa
     5941 agaagtcaaa agtctgttaa actattttca acaccaaact aaagaagaga acacaagttt
     6001 tttcgatgtt cactagagga aatggatttt attcagtaaa tccaactagg attgcacttt
     6061 ggttgccaaa attgcctttc cttcttttat caagggatga cggaatagtg agaagtacag
     6121 ttgaactgtc atggcaaccc agataagagg ttcacaaagg ataacaccct tatatcctgc
     6181 ccaaggaata atcaaaacca caaaaacgat ttttccgatt agttcaataa agctagaaac
     6241 tagaggaagg atcttctgcc ccaagccctg caagcaattg cgataaatca acaagaggct
     6301 caaaatggga taaaaggctg aactgatttg cagatagaga cttccatttt ctatcaagta
     6361 accatctgtc gaactagcca agaaggaaac caaggctgga ctggcaaaaa agaggaaaat
     6421 acaaacaaaa actgcccagg atatacttaa acgactgccg attcgaagac cttgaacaat
     6481 gcggtcaggt cgcttagctc ctagattctg agaagcaaag gtcgtcattg atgcagaaat
     6541 agcggtcata ggaagaaggg caaaggtcat aatgcgtcga gctgccgtct gggcactaat
     6601 aatcactgca ccaaatgtat taacagaaaa ctgtaaaatc acactgccga tagatacaat
     6661 tgaactcatc aagcccatag ccaaaccttg ctccaagaga tccgcgtaca agcttttgtc
     6721 ccatttgaaa tgtttaaact gtggcaagag ttctggcaca cttttacgaa tataataaaa
     6781 gcagagaacc gctgataaac cttgcgaaat aatggtagca agtcctgcgg attgaactcc
     6841 cagatgcaat tgcgtaataa aatagagatc cagaaccaca ttaaccaagg cagagaaaat
     6901 cagaaatccc agggctgcta gactgtcacc aatagaccgc aacaagcctg caaaaagatt
     6961 ataagcaaag ctgacaccta cacaggtcac aatcatagaa atatattgat aagattgagg
     7021 aagaatttct gcaggagtat ctaagtattg caagagagga tacaagccaa gaaagcccag
     7081 caacataact agaatgctca aaagagcacc taaaatccag gtggctgcta ctgcttcctt
     7141 gattttagtg aaattccgag ccccataata acgagcaatg acaatcccca tgccattgcc
     7201 aacaccaagt gtaaagccta caatcaggtc aaaaatcgct gtcgtcgctc ctactgcagc
     7261 caaggattct tgaccaagaa atcgtccaac aatcaagaca tcagcagtgt tatagagctg
     7321 ttgaaaaata tttgatagca agattggaaa ggtgaagctt aagagcgagg gaagaatcgg
     7381 accatgtatc aggtccactg ttcgtttttt attcataaag ctattatatc agctttccag
     7441 aggagcgaca agaaacagca aacttatata tagcggaatg aaataaggac agtcaaatcg
     7501 atttttaaca atgttttaga agtagatgtg tactattcta gtttcgatct attatagttg
     7561 gttgagtttg gaatagtacg ctgtagctgc taaaacattt ctagaaatta atttgacttt
     7621 cctaataaag ttgttcatat cttatttcaa gctactatat ataatctaaa aacttgaatc
     7681 aaaaatcgaa aaagtagcgg atttctccac tgctttaaca gcttattctt caatttcgat
     7741 ttcaagttca tcgcctaagt caagcggaac ttcttcattc actgcttctt ctttctttgg
     7801 ctcatctttt ttgttttcag tatcttgttc tgaaacttct tctccatcaa tcaagccaaa
     7861 tttagaacgg acttgcttat caatttcatc aaagatttct gggtgctctg ccaagtattt
     7921 cttagcattc tcagaacctt gcccaatttt ttcatctttg taagaatacc aagcccctgc
     7981 ttttttgata atatccaaat cgcttgcaat cttcaaaagc tcaccagtct tagaaattcc
     8041 ttctccgtac ataatttcaa ctacggcttc cttaaacggt ggagctacct tattttttac
     8101 aaccttaatc ttagtttctt taccgacatt ggtttctttt tgatcaccag ttcccttaat
     8161 ttgtgtatta ccacgaacat ccaagcggac tgaagcatag aatttcaaag cacgtccgcc
     8221 cggtgttgtt tctggatttc caaacatcac tccaactttt tcacgcaatt ggttgataaa
     8281 aatggcaatt gttttggttt tattgataga ggcgccaagt ttacgcatgg cctggctcat
     8341 catacgagcc tgcaaaccaa catggctatc tccgatatct ccatcaattt ccgcacgagg
     8401 aacaagggca gcaactgagt cgactacgac aagatcaact gcacctgagt caatcaattt
     8461 tcccgcaatc tcaagacctt gctctcctga gtctggttga gacaagagca attcgtcaat
     8521 attgacacca agggccgcag cataagctgg atcaagggca tgttccgcat cgataaaggc
     8581 agcaatccca ccttcttttt gcgcttgtgc aactgcatga agggcaaccg ttgtcttacc
     8641 agatgactct gggccataga tttcgatgat acgtccctta ggataaccac ctgagccaag
     8701 ggcaatgtca agagctaaag aacctgagct catcacttgc accttttgct ccgcacgttc
     8761 acccaaacgc atgattgatc ctttaccaaa gtctttctca atcaatttaa gagcatcatt
     8821 caaggccttt tcacgttctg ccccaaattt ttttgaaatt tcttctaatt tttttggttt
     8881 tttcgccatt ctattctcct acattctaat gatcctcaga cctatctact attatatcaa
     8941 aagttagtca cttaataaag ccttgcgaac taggttaaag gcatgcataa ccgcaatatg
     9001 acgtacatct gctcggcttc tgcctccaat attaaccttg ataacctcag ttccttgctc
     9061 ttgcgccaag cctatgaaga ctgtcccaac tgggtgtcct tctaggctat ctggtcctgc
     9121 cactccggtc aaactaattc caaaatcaga ctgggtcttg cttcgtgcct gctcagccat
     9181 cttctgagct gtaaattcag acaccacacc atgttcttcc aaattcttgg caggaatatc
     9241 caacatcctt gatttttcct ccaagctata ggtcacaaaa ccacccttaa atatacttga
     9301 agctccagaa aaattcgcca cggtagcttg gaaaagacct gccgttaaac tctctgcagc
     9361 cgcgatggtt ttcccttgcc ttttcagttc ttctaccaca atgctggcta aactagtttc
     9421 ttccccataa ccatagcaaa agtctcgtaa agaaattcct tcgaaagtct ggcagtccaa
     9481 gatttgattt tccaagatat ccagcgcttg attcgcctct tcttgactgc tagcctttgt
     9541 tgacagacgt agagtgactt ctcctgtctt ggcataaggg gccaaggtag gatcgatctg
     9601 attatcaatt aaatcagcca aaatcgtaac caactggctc tcgccaatcc caaagaaacg
     9661 aagaactcgg gaatacagct tgctccctgt catcaacttg ggtagaagtt ggtttaagac
     9721 catgggtttc aattcacttg gcggacctgg aaggacgaca taggtcactc cgtctacttc
     9781 taattttcct ccaacagcca gtcctgtttc gtttggcagt ggaatcgctc cttctacaat
     9841 ttgagcttgt ctttcgttat tcggtgttcg ggcatagtct ggtcgcaggg caaaaaagat
     9901 atccaacttc tcctgagcct gaggatcaaa gactaatgct ttccctaaaa atttagctag
     9961 ggtttgtttg gttaggtcgt cctcagttgg ccccaaaccg cctgtcaaaa tcaccagact
    10021 gctacgttga ctggcaatct caagcaaaga caagagacga acttcattgt ctcctacagc
    10081 cgtctgaaaa tatacatcta ccccaatctc agctagtttt tccgacaaaa actgggcatt
    10141 ggtgttgaca atctgtcctg tcaaaatctc tgttccaaca gcaatgattt ctgctttcat
    10201 gtttcctcct acctatctat tcgtattttt ttgaaaaaat cgcaggaatt ttcctacgat
    10261 tgattttttt atttgtatca aaagttaatt atcttcatca ccaacaggtg ctctgccaaa
    10321 taaatcttca aataaaaccg cattggtttc aagctgagta acttcttctt gtcccaaaga
    10381 acgtcggagt atattttgca tttccaacat atgtgctctc gaaacaatct ggtaagaaac
    10441 accttgaagt atctctcctt caccctgcaa ctgctgagtt tcaatggttt taaatgaatc
    10501 tttatagcct agcaagttag ggatactttt tgcagacaaa tcaatattgg tctgcatatt
    10561 gtcactcaaa gcttttagaa tctcttgata atgaccaacg ctatttaaac tgagagcttt
    10621 ttccatgact ttttgaataa cttcacgttg acgtttttga cgaccataat ccccctcagg
    10681 atcttggtaa cgcattcgtg catagactag ggcttcttct cccccaatat gttgctcccc
    10741 aacaccgata gaaatagtat taaattcttc ttggtcactg atagaaattg ggaaacctag
    10801 gatattattg actgtaatac ctcctactgc atccactagt ttttgcaacc ctctcatatt
    10861 gaccatcaca tagcgatcaa tatggatatt catcattttt tgaatggttt ctatagcaag
    10921 ctctgctcca ccatctgcat atgctgagtt cagtttcgct tcatgagcct gaccattccc
    10981 tgattcaatg cgcgtcagaa tatcccgctc taaactcatc attgttgttt ttttcgtttt
    11041 aggattcact gtcatcaaga tcatgctatc acttctaccg acccaagttt cagttcgttc
    11101 aacatttccg gtgtccactc ccattaacag aatggttaga ggttcagtcg cttcaataac
    11161 cttggtttct tcaccgattt ttttataggt tttagctaag gtttctgtcc cttgttgata
    11221 aatagtataa gcaaaaacac ctactcctac tacagttaca gaaagtaaag ctagcaccat
    11281 tccaataatt tttttaacca tatttctact aacctatcag tttacccatc aagtaaacat
    11341 cgataaattt cccttcttct atatatgccc cacgctcttg gctaccttca atgacaaagc
    11401 catgcttttg ataaagatgg actgctgctt gattacgagt ttggacagtc agttggagac
    11461 gacgcagaat gccacttgct tgtgcccact ctatcgcttc ttctagcaac aaacttccca
    11521 agccattatt ccaatatctt tttccaatca caatgaagag ttctccaata tgacggactc
    11581 tcttacgctg gtcagctgta atatttacaa taccagcaat tttgccattt aagaatgcaa
    11641 gtaaggttat ctgattgtcc gaactagctt gcttgttgag gaatatttcc atctcctcac
    11701 tagtcaagag aataccatct ccgtctaggc tggtaaagtc tgtctccaaa ctcacacgat
    11761 ttaaaaaggc cactaattca gctgcatctt tgggctctgc ttccctaatg agcaattcat
    11821 actccatatt gaagctcctc taacaatttc tcagcacgca aaccctttgc ctgaaaattt
    11881 aaacggcgtc catctgcttc ttttagaatt tccaattcta aataagcatc tggcaaggca
    11941 tctcctaaga gattgcccca ctcaataaca gtcacgccgc caccaaagat aaactcatcc
    12001 aagtcgatag aatcagcatc tccttcaata cgataaacat ctaggtgata aagtggaagt
    12061 cgaccttcat actctctcac gatagtatag gtgggacttt taatcatttg agaaatctgt
    12121 aatccttttg caagtccttt agtaaaggtc gttttacctg cacccagttc tccagttaag
    12181 attaaaacat cattctttgc taatagatgg cccaaacgct cccctaaggc ttgcaactct
    12241 tcttcatttt ttgtgtacat actcttatta taccaaaaac ttttcttttg tgtctatttt
    12301 cctactaaac ttatcatcat aacatccata aaaaacaggc tttctctaaa agaaaatgag
    12361 cgtaacaatg accaatacaa gatctcggaa aatatgacca taaaaggaaa cttccttctt
    12421 aaccgaattt gggacaagat aggctgcaaa aaacaagccc agtccaatat aaatcagaag
    12481 tgagacaatg gtcattggat ttcttaagaa aagaagtgtt gctaaaatag tcaccaacac
    12541 tgtctttttt ctgtctagca tagcaagaaa atcgcgcacg tattttttca agggtaaaaa
    12601 aatcagcaaa tctagcccaa ataggaaaaa gaaggatggc aataaaaagt caactaattc
    12661 ttgctgcagc gtatttttga tgaacaagtt atctgacaaa acaagaacag ctcctaacaa
    12721 attaattaag agtaacatac tgtaaaaaag cttcacagac ttcttactgg ctaggacact
    12781 atggacttct tgcttacggg tataaagata atttactcca gcacagattc ctgaaacgaa
    12841 aaccatgctt ccgatgaaaa aaactgtact ttgtttaaag gacaagatgc attccttcca
    12901 taggaaacag ctactcaaac tgatttgaat taaagctaac aaaaataaga ttctcattga
    12961 tttcatcttc tctctccctt cctaccaatc attatactag gagaaaagag agaactgttt
    13021 ctaatcttct caaatgtctc tttaagacgc taaacaaaca ctagagacta atactcaatg
    13081 aaaatcaaag atcaaactag gtagctagcc acaggttgct caaaacactg ttttgagatt
    13141 gcagatagag ctgacgtgat ttgaagagat tttcgaagaa tataaatttg aaatcatgaa
    13201 aatccgtcaa acgggtggtt gttttgtctc gcacctcacg gagcgagacg gactcagagt
    13261 cacataatta taaggctgat agtattaatc taactatcag ccttacaggt tatttaacgt
    13321 ttcagaaaaa ctataatgtc aagattaact aaacagtatc taattccttc aaataatttt
    13381 ctatcttcat caacattaaa ggattgttat aaatcttaca taactctctt gcttctatat
    13441 aataattttt gacttgttct ctgtctagaa atttggctcc agcatttcct acaagaataa
    13501 gtagaggagc caattggtag cttgtctgtc tttgtttaca gagttcaatc gtttcaagag
    13561 cttcttggat ggcttcatta tatttttcct ttgatactag gtagtgagcg tagttgtaac
    13621 gaactctgat gtagccaaat aaaaactctt gatggtccaa attttttgtc tgatacaact
    13681 ctattaaatg agagtagttt gcctcatatt cttgttcacg acccactaag gaatagaaat
    13741 tagatagagt attcaacgcc tttaaataaa tcagagtatt tgaagagact tttaataata
    13801 tattttccaa tgacgaaatt gcctcacact tactgtcata ttgatagaag tcaattatag
    13861 atttaatcca ttcaaggtaa gttcggtctt ctaatgttag aaaagtgctt cgttctacct
    13921 ctattttata aagatattct aaatcgtcat aatttctgtc atctaatagg cgagcagata
    13981 gatgtttgaa attagagagg ttagacttaa cttcgatttg ttcattgaaa aagtaatcca
    14041 aagggacttc aagtcgttga gagagtttga ataacaagtc tgcggaggga ataaaatgac
    14101 ctctttcaat tttactaatc tggctttgtt cacaaattcc ttctgcaaga gtttgttggg
    14161 agagtctcaa ctcttttctt ttcaatctga atttctctgc gagtgtattc attaaagata
    14221 ataaaccttc ctatttgctt aatttcatta taaagttttt agttcaaaat agcaagttaa
    14281 aggaataaat aattctttat ggtaataaac aaaaaaaaaa gttaaaaatt acataaaaat
    14341 acttgactaa ataaaatata tctgttagaa taaaaacaag gaaaaagaaa ggggtttcat
    14401 tgcatgagaa aaaaacgtgg aattaaaaaa ttagttacat ttgcattgct aggtgttttt
    14461 atgtttagta atacaattcc ttaccaacag tttattcaga agaataaaca attggagatt
    14521 cgagtgtaat cgcaaaagaa gtccaatggt cttgatgttg ggaaggctga ttaaaacccg
    14581 atattttgca cgagaatgag agaattataa tttatctgaa aaaacgaaaa atatagagca
    14641 acttatttaa ctttttataa ggaggagtta ttacttatga ccaactttaa ttcaaacgaa
    14701 aaattttgtg gaaaaagttt aaaatcattg tctgctgatg aaatgagttt aatttatggt
    14761 gcatctgatg gtgcagagcc acgttggacg cctactccta ttattttgaa atcagctgca
    14821 gctagctcga aagtatgcat tagtgcagct gtttctggta ttggggggct agttagctac
    14881 aataatgatt gtttggggta aattaaaatg aaaaatgatt ttgtaatcgg aaagagtttg
    14941 aaagaattat ctcttgaaga aatgcaattg gtttatggtg gcacagatgg tgctgaccct
    15001 agatcaacaa ttatatgttc tgctacatta agttttattg catcatattt ggggtcagct
    15061 cagactcgtt gtggcaaaga caacaagaaa aaataaaata ttcaatttta aaaataaaag
    15121 ttgctcttta ttttcctctc tcgtaactaa taattttgag agaggttttt ttttaaaaca
    15181 atagtaagtc gtataggttt gaggtaagta aatgaaatat aaaattaaaa atgtgcataa
    15241 aacattgttt attaaggaaa gatatcaaat attatctgaa cgaaatgata attccttaaa
    15301 taacttttca gaaataattg gcgttctaca atgtcaatta tttctgaaaa aacttttgaa
    15361 gaaatgttga aattaaataa ttacaataaa aaaatatttt ctaacactgt gaactatgat
    15421 tataccgagg aacagataag actatattca gaatatgcca aaaattcgga atggtataaa
    15481 tttgcggagg gttcatttga aatatttaga aaacatcccc aaagaattaa ttttaagaaa
    15541 gatttttcta gaattttgga accctttatt attaatttgc ttaaattaat caataattat
    15601 ctagagaata aagaatacga gtggattgac aagaatggaa atattttttc ctctctagta
    15661 ttttatttag aagatttaat ctatccttgg attgttaaac ctttggtttt agagataaat
    15721 tcattgcgtg aaaaaggttt acttgaaggg gaatcggagc agcaacggta caaatatttt
    15781 ataacattgt ttgacaagga agagaatata ttaaattttt ataacaaata tcccgtttta
    15841 ctgaggcaaa tatcggagtc ttgtcttcgg ttctatactt attttataga aattttatca
    15901 aatttagaaa atgattttag tgtgctagaa gaagaattag ggctaagggg gaaattaaat
    15961 gatataaaat ttggaaaggg tgatacacac agccaaggaa aaactgtttt gatactcttc
    16021 tttgatgacg cgaaaattgt ttacaagcct aaaaatttaa taatcaataa ctcactaaat
    16081 actattgctg agtatatccg aaaggttgat gaaaaaatta ggataagaat acctcgaact
    16141 attgcttatt cggatcacag ctatgaagaa tttattgatt atctacctct agagcaaaag
    16201 aaaaaattac ctgaatatta ttataatttt ggtgtgcttt tagcatttat atatttattt
    16261 aatgggagtg atatacattt tgaaaattta atttcctatg gagatatgcc tgtaataata
    16321 gactttgaaa caatgttaca gcaacctcta tttgatgata aaactggtca gagtttgctg
    16381 gataccctgt ttcacagggt gactcgaact ttgcttcttc caacagaggg agtaaaaagg
    16441 gaggatggtc ttgatgttga gatgagtgct cttacaggaa attttaagaa ggatgctttt
    16501 aatggtcaag ttttaattaa tttaaatact gataaggtaa agtttgatat tgggaaaatt
    16561 gattttgaag gtgggaaaaa cctgcctgtt cgggatggtg atatagaatt tgataagtat
    16621 ataaaagatt tcaaaaaagg ttttagggat ttttatctga tatttgaaga gttaaataaa
    16681 acagaagaat ttaaaatgct attaaaagca aacttgtatg gtttaaagac aagggtactt
    16741 tttagagaca caaatagcta tgcttcagta ctatcttttt tatatcatcc tgatttttat
    16801 gaagaaatgt tagatagaga aaaagcattg gaaaatctct ggagcaataa gttttctaat
    16861 caaggtattg tagcaagcga atgtgaacaa atgaggttat tagatattcc gattttttat
    16921 acagatacaa atatcaatga aatctacgat gattttggaa atcattttat ttccctacat
    16981 caattttctg gatatgacta ttttatgaaa tatttaccta ataataattt ggaaaattta
    17041 gaaaagcaac ttgatatcat tgaaatttat tttccaagct ttgatcagcg aaaaaaagga
    17101 tataaattaa acttatctaa tagaaaaaaa ctcccaaatg aaagtttagt tactattctg
    17161 cataatgaag tagaaaatat tgcagactct ttggttatta ataatattta tgacgaatat
    17221 ccaatttgga gtatacctgt taattttaaa ggttctaaat ggtgtcttga acaaacgggt
    17281 aatgatatgt ataggggtag agctggaata ttactgttta tgtactatgt aaaattattg
    17341 aaagataaat catcatatac tcaactgtac aataaaatgt tatctgcaat tccgccatct
    17401 gtttctttat ctaagaccac atttggttta actggggata taggatattt cattgttcta
    17461 tccattatag aggattacga tacaaatact ctcgcatgct taaattatat aaagagtgtt
    17521 ttaactgagc ttgaaaagac tgattttgca agtgtttcaa acaagtctga ctatattaat
    17581 ggtcttctac ctttaattaa tacactggta agatattata ggagaggaat agagaaggaa
    17641 cgtgttctaa ggctagtatt aagtttaggt gatacgctat ataatgatgt aagcgagaga
    17701 gataatagta attttggata tagttttggc catggactat caggtgtaat ttttacatta
    17761 aaaaatattt ataaagtgac aagacttaaa aaatataaag aattaatttt acaactagtt
    17821 cctagggaga aaatcaaaat tcattctttg aagtggtgta gtggagaatt tgggacatta
    17881 gttaatcatc cccaaagtgt tccagaggga attgtagcta gtttagataa tgatacattt
    17941 tgccatggaa gtatggccat aataaatttt tacatcgact acatgaaaga aatggatact
    18001 agtatggaat tggagtcttt attgtgtagt gttgtaatga ataaatcaaa agaaggagag
    18061 tatcgtatcg tccaaacaag caatttccca gatttttctt tgtatacagg tgtgactggt
    18121 attgcttata cttttttaag gtatatcgca ctgaatcaga atgacaaaaa gatagttatc
    18181 ccctcattac ttgaaatcta gcttaattta tagttttgtt tctaaaatag aggtgtccac
    18241 tcattaagca atataaaaat accaagattg actagtttaa tatgtaattc tataaaatat
    18301 ttttaatagt gtagcttttc gttgagataa taatataata aagaaaagtt ctattctaat
    18361 tgctaaacgg cttgaggtat atgctactgt tatagaaatg attttaaact aaaatcaaaa
    18421 ttactccaaa aatagtattg attttggttt aatacaaaac atatgtaata atgtgagtca
    18481 acaaaagtct gtttttgtac catactatct tgaaaaatct actaaattca aattgagagg
    18541 atgaattaaa atgaataaaa tatttatata tgcaggagtg cgaaatcata actctaagac
    18601 tttagagtat actaagagac tttcaagtat catttctagt agaaataatg ttgatatatc
    18661 tttcaggaca cctttcaatt cagagctaga aatatctaat tctgattcag aagagttgtt
    18721 taagaaagga attgataggc aaagtaatgc tgatgatgga ggtgttataa aaaaagagtt
    18781 attagagtct gatattataa ttatctcttc tcctgtatat ttacaaaacg tatctgtgga
    18841 cacaaaaaac tttattgaaa ggattggggg gtggagccat ctttttcgat tagctggaaa
    18901 gtttgttgta acattagatg ttgctgagag taacggctct gataatgtgt cagaatatct
    18961 tagagatata ttttcatata tgggaggaca gatattacac caagtttcaa ttaccaattc
    19021 actcaaagat attgcagagg ctcagttgat ggaggcaact tataaaattg aagatgtact
    19081 tgaagggaaa attaagtaca aaacaacgga ttatcaagaa agagcttacc agacattaaa
    19141 attaatttta gaaaattatg attccgaaca ttttgagaag atgtattggg agaaaaaacg
    19201 cctttttgaa gctaatagtt tagaggaatg gtattatgtt gaaaatatta aataactctg
    19261 tcatatattt atgtttgatt ccgttattgt tcctattatt gataattttt ccaaatgatt
    19321 cattaatcta ttattttcga ttgattttaa tttcgttaat atcaattaca ttacatgaac
    19381 taggtcattt tttagtggga agatgtttat cttataaact agagatgctt gctactccct
    19441 ttttcttcta tttcagaaaa aaaatatatt tcaaatttcc agtgttatta gcattcggtt
    19501 attgtcaaat gagtaataga aacattacta atgaaaaaaa tagtgatagg aatttggtgt
    19561 tctacttctt tgggggaggt ggagctaacc taattgtcgc aatattagca cttttgggat
    19621 ttgtgccgta cgcatcagaa ttttttattt tgaatataat tctttttcta gttacggtat
    19681 gtttaccaat tgatggaaca gatggcaatg ctattagaga gatagttttg tattcaaaag
    19741 attcaaaaac atatcagaga ttctttgcga acagtctcta taataatcct tatataacaa
    19801 tcgacgattt tgcaaaatta acctctaaag aaaaatcttt tttttcaaaa tttgaaaaat
    19861 gtttgataaa cctttacttt gaagtgaaag gtgaagggtc agcatttaca attgctaatc
    19921 atgaagtttt tgattcaaat attcaggaaa atattatcca tgagtactat aaattactac
    19981 ataaatcttc tgattggatt attccacaga acttatcttt agaagaagtt gtttttacct
    20041 tgtcaaacta tatttactcg aaaaataata aatatttaga aaagattaag tatctaaaga
    20101 aattagtaga ttttagacaa gaagaaatta tcgactttat tttgaacaag gaggaagtat
    20161 tgtgaaaatt ccaatgatat atcaaatgga aaattcagaa tgtggattag catgctgtgc
    20221 catgatattg aactatttta aatatgagat ttctttaaat gaactacgtg aaatctaccc
    20281 atcatccaga tctggatatt ctctcctatc tataagtaaa gttttaggag attttaatat
    20341 aagttctcat gcttttaaag cttcggtaag agatttaaaa ccgctcagtt tcccactcat
    20401 ttgcttctgg gagagttctc attttattat tcttgaaaaa attagtaaaa acaagtttta
    20461 tattttagat cctgcaaaag gcaggcagag aatgtcaata agtgaatttg aaaggcatta
    20521 ttcaaatatc attttaacat ttaaaaagtt agatagcttt atgtctcgta aagataataa
    20581 gaagtcgcct gttttaaagt atttttttaa gtataggaat aagctaggga ttttattttt
    20641 tgtaacagca ttattgtatg taatacaatc attagtacct atagctaata gatacataat
    20701 tgacacgaat ttcaaggacg attcgtattc gtctagaatg ttatttacta tattatttat
    20761 atttactgtt tcattctcac taatgtattt attaagacag atatatgttg catccttaaa
    20821 atatataatg gataaagaga ttagctatga ttttatgaaa catttgatat atttacctta
    20881 cagtttttat gaaaaacgta ctttagggga tatacttttt agagctaact ctattgttta
    20941 tataagagaa atactatcaa ataattttat agcagctata cttgatttgt taatgattgt
    21001 ggtttatgct gtggttttat ttagcttttc taagtacatg gtaatctttt taatatcact
    21061 aagtctagct ctatctattg taatgtatcc aatcataaaa atctcaaaaa atttaattga
    21121 taaaaatata aaagaaaagg ttaatgttca aaatattact tccgaagtaa tttctaaaaa
    21181 tagtgatatt aagctaactg gagaagagga attttggatt aacaaatggg ataattttaa
    21241 tacaaaacag ctcatcatag gtcgaaaact tgatatacat ttatcaattg ttagtagtat
    21301 aacgaatgtt ttacaaatta ttctccctgt tttgaccctt attgtaggtg taaatataaa
    21361 aacattcgaa caattgacgt taggacaaat tgtagcaata agtacagtct caccatactt
    21421 tatttctcct ataatttctt taagtgataa ctatatacaa ttaatgttat taaagggata
    21481 ttttttaaga atagaggatg tgtttaatac taaatccgaa ttaattccag aaagagtcag
    21541 tcaagatata aaatttgata aaaaaataga attaaaagat atttggtata aatatggatt
    21601 atttgatgat tatgttttga aaggaataaa tgttactatt aaaaaaggag aaactgttgc
    21661 tattgttgga gaatcaggtt caggtaagag tacattagct aaaattttat taggtttatt
    21721 agaacctaat attggttcaa tagaagttga tggagtagaa aaagaagaaa ttggtcaaac
    21781 attgtataga aagatttttg gagcagtgtt acaaaattca accctaagtt atggtacctt
    21841 aagagagaat ttgacatttg gacactttgt ttcagatgaa gaattaatga caaatctaaa
    21901 ttcaattggt cttagcaatg tagttaaatc tttacctctt ggattagaga caatcatcgc
    21961 tgaagaaggt aataactttt ctggagggca gcagcaaatg atacttttag ctcgttgtct
    22021 tttgtcgaaa ccttcggtag ttgttttgga cgaagcaaca agtagtttag ataatttatc
    22081 tcaacaaatt acaacttctt acttaagtga aatcggtacc actaagattt taattgccca
    22141 tcgactagat actatcaagt ctgcagataa gatcttagta atgcataatg gtgaaattgt
    22201 agagattggg acccatagag aacttcttga actaggaggc atttataagc aattgtattc
    22261 aaataattag tttttgatta aaagggtaaa tttatgaaga ttatgaaaaa aaaatattgg
    22321 actttagcga tattattctt ttgtttgttc aataattctg ttactgctca agaaatacct
    22381 aaaaatcttg atggcaatat aactcacact cagactagcg aaagtttttc tgaatctgat
    22441 gaaaaacagg ttgactattc taataaaaat caagaagaag tagaccaaaa taaatttcgt
    22501 attcaaatcg ataagacaga attatttgta acaacagata aacatttaga aaaaaactgt
    22561 tgtaaattgg aacttgaacc acaaataaat aacgatattg ttaactctga aagtaataat
    22621 ttactaggcg aagataattt agataataaa attaaggaaa atgtttctca tctagataat
    22681 agaggaggaa atatagagca tgacaaagat aacttagaat cgtcgattgt aagaaaatat
    22741 gaatgggata tagataaagt tactggtgga ggcgaaagtt ataaattata ttctaaaagt
    22801 aattctaaag tttcaattgc tattttagat tcaggagtcg atttacaaaa tactggatta
    22861 ctgaaaaatc tttcaaatca ctcaaaaaac tatgtcccca ataaaggata tttaggaaaa
    22921 gaggagggag aggaaggaat aatatcagat attcaagata gattaggtca tggtacggct
    22981 gttgtagctc aaattgtagg ggatgacaat attaatggag taaatcctca cgttaatatt
    23041 aacgtctata gaatatttgg taagtcgtca gctagtccag attggattgt aaaagcaatt
    23101 tttgatgctg tagatgatgg caatgatatt atcaatctta gtactggaca atatttaatg
    23161 attgatggag aatatgagga cggaacaaat gattttgaaa catttttgaa gtataaaaag
    23221 gctattgatt acgcgaatca aaaaggagta attatagtag ctgcattagg gaatgactcc
    23281 ctaaatgtat caaatcagtc agatttattg aaacttatta gttcacgcaa aaaagtaaga
    23341 aaaccaggat tagtagttga tgttccaagt tatttctcat ctacaatttc ggtcggaggc
    23401 atagatcgct taggtaattt atcagatttt agcaataaag gggattctga tgcaatatat
    23461 gcgcctgcag gctcaacatt atctctttca gaattaggac ttaataactt tattaatgca
    23521 gaaaaatata aagaagattg gattttttcg gcaacactag gaggatatac gtatctttat
    23581 ggaaactcat ttgctgctcc taaagtttct ggtgcgattg caatgattat tgataaatac
    23641 aaattaaaag atcagcccta taattatatg tttgtaaaaa aaattctgga agaaacatta
    23701 ccagtaaaaa atggtataaa agtgttaaat ataccaaacg tattgagata tgatttgaat
    23761 atgttacaat tagaatataa aaatgaacaa agttgggata gtttcataga taatgttaat
    23821 ttaattgagt tggaagagag aattcaaact actattggaa ttaaacaaat aaacacacac
    23881 aatattatta ctattgcccg agaagggtac tctcaaaatt atttacctaa cacttcagaa
    23941 aatacatata attcattaca agtcagttta gttggagtat tactactttt tataagtatg
    24001 gtaaatattt tatgggctaa aaaaagtaaa tgaaaataaa atttggagcc ctctgaaaaa
    24061 gtaagtccta cagttcaact aaaatgagtc aaaagatgaa tcaccttgat gtaggggagt
    24121 ttgtcttatt gctgcctgaa cacctccgtt cagaggaaga acattataaa tctgtttttg
    24181 aagacgactt aaccagtcgc atatctagtc aagatgaacg acagcaaatg actgctacgg
    24241 taggttattt agaatcaggt caggatcgtt ttgtgtataa tacgacccct atttcttacc
    24301 agcagttttt gaaagatcca atcatcattg ttataacacc ccaatcaact ggtccacagt
    24361 ccattttgtt ttggatagac gcagtacaga actacgttct ctttaatcaa ttgtctgatg
    24421 cccaggagct tatccagaga caaggcattg aaaattgggt ctcagaaatg caaacaggtt
    24481 accacaacta catcacatta ttggataata tccagaggga acgttgggta atgctagcag
    24541 gagctgtgct tgggattgca acttcaatct tgttgtttaa cactatgaat aggctctact
    24601 ttgaagaatt tagacgtgcc atttttatca aacgcattgc aggtctcagg ttcttagaaa
    24661 tccatcgcac ttatctcttt gctcaactgg gtgtgttttt actgggattt gttgcgagtg
    24721 tatttcttca ggtagagata ggagttgctt tcttagtctt gttactcttt actggtctat
    24781 ctcttttaca gttacatgtc caaatgcaga aagaaaacaa gatgtccatg cttgttttga
    24841 agggaggtta atatgattga acttaaacag gtgagtaaat cttttggaga acgagagtta
    24901 ttttcgaatc tttcaatgac atttgaggct ggaaaagtct atgccttaat tggttcaagt
    24961 ggtagcggaa aaacaacctt gatgaacatg attgggaaat tagaacctta tgatgggacg
    25021 attttttacc gaggtaaaga cttggccaat tataaatcaa gtgatttttt ccgtcacgaa
    25081 ttgggctacc tcttccagaa ctttggctta attgaaaacc aaagtattga agaaaacctt
    25141 aagctaggtc tcattggtca aaagttgagt cggtcggaac agcggttgag gcagaagcag
    25201 gctttagaac aggtcggcct ggtttatctt gacctagata agcgcatctt tgagttatcg
    25261 ggcggagaat cgcaacgggt tgccttggca aaaattatct taaagaatcc accctttatt
    25321 ctggcagatg agccaacagc ttcaatagac ccagcaacct ctcagttgat tatggagatt
    25381 ttgctatctc ttcgagatga taataggcta atcattatcg caacacataa tccggcaatt
    25441 tgggagatgg ctgatgaagt gttcacgatg gatcatctga aataaaaatc cttgttttta
    25501 attgcacgat gagttactga aatattatca tgaatcaaga attggagtta atttagaatt
    25561 gtactttatt aatattgagg taactttttc ttgataaagg aagaaataat ggagaggaag
    25621 ttagaatgaa aaaattcgac aattatatta ttgagaagcc ttgcgattct aattcagata
    25681 aactgcaaaa aatcttaata attgaaagtt tggtagatga tattttgcaa ttttctctca
    25741 gaatcaataa tagtgtagga gagattttcc tcctacaacc gttttaaaag aaaactatct
    25801 ttattccatg ttattttgag gaagatattg tgaaagtcaa agatgatgat aaagttgagt
    25861 ggaatttgtt agaatttcaa aaatttagag catttttggc ttagtaatct gtgttgaagg
    25921 ctcaaaacct atggtaaaaa agtagctttg aaaacgtatt gcctccaaag atttagttaa
    25981 ataatgattt aacacaaaaa gaaattattg aagttctgga aagatgttgt ttcagtattg
    26041 agaaaaggtg ggaaaaactt gcgattttca cagagaaagg aagaaaaagt atagaaatat
    26101 agtcaattga aacaagaaca ggataaaaga accttttgtg ccatattttt ctcctttcgc
    26161 tttacaattg gattgaacac ctttattgta tcgcgtttgg agtttttttg gtataacctt
    26221 cgacgcacac ccgcatagcg ggtgtttttt ttgtctcgca cctaacggag cgagacaaac
    26281 taatagtcac ttaatcaaaa aacgcaccat atcaaaaact aaaaagtttg atatcatgcg
    26341 tcatgtctta aactaattga ctatactttc tattcaaatg agcttttaac caattgattg
    26401 agccaatcca ctcttaaaac caaagagcaa tttctcgctt agctgactct tctgaatctg
    26461 aaccatgtac aacattttgg ataatctcat tttctccagc agcttttgca aaatcacctc
    26521 gaatagtgcc tggtaaagct tcttctggac gagttgcacc catcatggtc cgccaagttt
    26581 cgattacttt gggaccagaa atgacaccca caagaactgg acctgaagtc atgaattcac
    26641 gaatcggtgg gtaaaaactc tgaccaacca agtcctgata gtgctggtca atcaactctt
    26701 ctgaaacctg tgaacgaaac tccaattttt cgattgtaaa tccacgttgt tcgatgcgct
    26761 ttaacacttc acccactagc cctcttttta caccatctgg tttgatgata aagaatgttt
    26821 gttccatacc cgtctccttt gtcagcttct ttcttttatt ttaccacatt tcgtggaaaa
    26881 atggagaaag ttttcagaag agagaatgag agaaccctcg ggttctctca ttctctctta
    26941 ttctactgtt tcttccacag tttcaacggc agtatccaca actacttctg ttgtttcttc
    27001 atttccttct tcctctactg gaggattaag gtattcttct tcgttgacag catgtggttc
    27061 aaggttacgg taacgggcca taccagtacc agctgggatg atcttaccga tgataacatt
    27121 ttctttaagt ccaaggagat ggtctttctt accacggata gctgcgtcag taaggacacg
    27181 agttgtttcc tggaaggaag ccgctgacaa gaaactgttt gtttcaagtg aggctttggt
    27241 aattcccata aggactgggc gacctgtcgc tggaactcca cctgcgataa ggacatcttt
    27301 gttggcatct gtaaagtcat tgatatccat gagggtaccc atgagaagat ctgtatcacc
    27361 tggatccatg acacggactt tacggatcat ttgacgaacc attacctcga tgtgtttgtc
    27421 accgatttct accccttggc tacggtaaac tttttgtact tcaccgagaa ggtacgtttc
    27481 aactgacaag acatcacgaa ctgcaaggag acgttttggt tggatagaac cttctgtcag
    27541 agcagcacca cgcgctactt ggcccccaac ttcgacacgc atacgagctg taaatggaac
    27601 gacatattca ccttcgccag tttcaccctt aacaaagact ttcttggtac gagttgatgc
    27661 atcttcttcg atagcagtaa cttgtccttt aacctctgta ataaccgctt cccctttagg
    27721 attgcgggct tcaaagattt cttggacacg aggaagaccc tgagtgatat cggtatttga
    27781 ggcaacccca cctgtgtgga aggtacgcat tgtaagctgt gtaccaggtt ccccgataga
    27841 ttgggcagcg attgtaccaa ctgcttcacc aacttcaacc gcatcaccag tcgccaagtt
    27901 gataccgtaa cagtgacggc agacaccgtg acgagtgtta catgtaaata cagaacggat
    27961 agtcacttct tccacaccag cattgacaat ttcacgcgcc ttgtcttctg taatcaattc
    28021 atttggacca ataatcactg caccagtttc tggatgttta acagttttct tagtgtaacg
    28081 accgttgaga cgctcttcga gagactcgat catctctttt ccttctgcga tagaacggat
    28141 caagagacca cggtcagttc cacagtcgtc ctcacggatg ataacgtctt gggcaacgtc
    28201 gaccaaacga cgagtcaagt aacctgagtc ggctgtctta agggccgtat cggtcatacc
    28261 tttacgagca ccgtgagttg agaagaacat ttccaatacc gacaaacctt cgcggaagtt
    28321 tgaaaggatt ggcaattcca tgatacgtcc attcggagca gccatcagac cacgcatacc
    28381 ggcaagctgt gagaagtttg agatgttacc acgggctcca gagtccatca tcataacgat
    28441 tgggttctta ggatcttgat tagcaatcaa gcgtttctca agtttttcac gggcagcacg
    28501 ccattcagct gtaacagcat tgtaacgctc gtcgtctgtg atcataccac gacggaattg
    28561 tttggtgatt tgttcgacac gtttgtgtga ttcttcaatg atttcagcct tgtcatcaac
    28621 gactgggata tcggcaatac ccactgtcaa tcctgcaaga gttgagtggt ggtaaccgag
    28681 gttcttcatg cggtcaagta gggcagaagt ttctgtcgta cggaaacgtt tgaagatttc
    28741 agcgatgata tttccgaggt ttttcttctt gaatggaggg ttgagctcaa gattgctgat
    28801 agcttccttg atagctccac caagtggcaa gaagtattta gctggaacac cttctgtcaa
    28861 gttggcattg tttggttctt gcaagtatgg tagcccctct ggcatgatat cgttgaagag
    28921 aattttacca actgttgtaa gcaagacctt atgtctttgc tcttctgtcc aaggcttgtt
    28981 gaggctgtct gttgcgatac caacacgtga gtggaggtga acataaccat tgcggtaagc
    29041 cataaccgct tcgtcacggt ctttgaagac cattccttca ccttcgcgac cagcttcttc
    29101 catggtcaag tagtagttac ccaaaaccat gtcctgagat ggagtaacta ccggtttccc
    29161 atctttcggg ttcaagatgt gctcagcagc tagcatgagg atacgagctt ctgcttgtgc
    29221 ttcttctgaa agtggtacgt ggatggccat ttggtccccg tcaaagtcag cattgtaggc
    29281 ttcacagaca agtgggtgca agcgaagagc cttaccatca atcaagactg gctcgaaggc
    29341 ttggataccc aaacggtgaa gggtcggtgc gcggttcaaa agcactgggt gttctttaat
    29401 cacttcttca aggatatccc agatacgctc atctccgcgt tccaccaagc gtttagctgc
    29461 tttgacgttt tgcacgatat cacgggcaac gatttcacgc atgacaaatg gtttaaagag
    29521 ttcaatcgcc atttcacgtg gcacaccaca ttggtacatc ttaagagttg gaccaacggc
    29581 gataacggaa cgtcctgaga agtcaacacg tttaccgagc aagttttgac ggaagcgtcc
    29641 ttgtttacct ttaagcatgt ggctcaatga tttcaatgga cggctacctg gtcctgtgat
    29701 tggacgacca cgacgaccat tgtcaatcaa agcgtcaact gcttcttgaa gcatacgctt
    29761 ctcattttga acgatgatac ctggtgcatt taactcaagc aaacgagcca aacggttgtt
    29821 acggttgata acacggcggt aaaggtcatt caagtcagat gaggcaaaac ggccaccatc
    29881 caactgcaac attggacgaa gatctggtgg gataaccgga aggatgttaa gaatcatcca
    29941 ttcaggtttg tttccagact tgtaaaaggc atccaaaaca tccaaacgac ggatggcttt
    30001 gacacgtttt tgtccagtag cagttttcaa ttcttctttg agttcagcaa tttctttttc
    30061 aagatctact tgcttcaaaa ggtcttggat ggcttccgca cccatcttag caacaaatga
    30121 accataacca tattcgcgca agcgctctcg gtattcgcgc tctgtcatga tagacttgtg
    30181 ctcaagtggt gtatccttag gatcaatcac cacataagcc gcaaagtaga taacttcctc
    30241 gagggcacga gggctcatat caagggtcaa gcccatacgg cttggaatcc ccttgaagta
    30301 ccagatgtga gatacaggag ctttcaattc gatatgtccc atacgctcac gacgaacttt
    30361 cgtacgcgtt acttcaaccc cacagcggtc acaaacaatt cctctgtaac gaatgcgttt
    30421 gtacttacca caagcacatt cccagtcttt tgtaggacca aagatcactt catcaaagag
    30481 tccttcacgt tctggtttca aggtacgata attgattgtt tcaggttttt tgacttctcc
    30541 ataagaccat gaacggactt tacttggaga agctagggtg atttgcatac ttttaaaacg
    30601 atttacatca accactattt cttccctttc tattctaagt gaactgctta ttcttgttca
    30661 gcagcttctt ctgttgcttc cgcttttgtt gctttctcag cttcttcagc ttcaaaggct
    30721 gctttagcct cttgggctgc tttttcgcgg gctttttcaa ggtcatctac gtggatgaca
    30781 tcttcgtcca ttccttcatc caagtcgcga agttccactt cttggtcatc ttcgtctagg
    30841 acacgcatgt caagaccaag agattgcaat tctttgacaa gaactcggaa ggattctgga
    30901 acacctggtt ttggaattgg tttgcctttt gtaatagctt cataggcttt caaacgtccg
    30961 ttgatatcgt ccgacttgta agtcaagatt tcttgaagga catttgacgc accgtaggct
    31021 tcaagagccc aaacctccat ctcaccgaaa cgttgtccac caaactgagc cttacctccg
    31081 agtggttgtt gggtaacagt tgagtatggt ccgactgaac gcgcgtgcaa tttatcatca
    31141 accatgtggt ggagtttgat catgtacatg actccgacag aaacacggtt atcaaacggt
    31201 tcaccagtac gtccatcgta aaggatcgtt ttggcatcgc tatccatacc tgcttcttta
    31261 acagttgacc aaagatcttc agaacttgct ccatcaaaga ctggtgtagc gatgtgaata
    31321 ccaagagtac gagctgccat accaaggtga agctccataa cctgaccgat attcatacgt
    31381 gatggtaccc caagtgggtt caacatgatg tcgactggag ttccgtctgg aaggtaaggc
    31441 atgtcttcta caggaacgat acgagagaca acccctttgt ttccgtgacg tccggccatt
    31501 ttatctccga ccttaatctt acgtttttga gcgatgtaaa cacgaaccaa catgttaaca
    31561 cctgattgca actcatctcc atttacacgt gtaaagatct taacatcacg aacgacacca
    31621 tcggcaccgt gtggtacacg aagagaagta tcacgcactt cacgagactt gtctccaaag
    31681 atagcgtgca agagacgttc ttcagctgaa agatctttct cacccttagg tgttacttta
    31741 cctacaagaa tatcaccttc tttaacctca gcaccaatac ggataatccc catttcgtca
    31801 aggtctttga gggcatcttc accaacgttt ggaatttcgc gagtgatttc ttcaggccca
    31861 agctttgtat cgcgcgtttc tgattcgtat tcttcaaggt gaacagatgt gtagacatcg
    31921 tccttcacca agcgttcgct catgataacg gcatcctcga agttgtaacc ttcccaagtc
    31981 atgtaggcaa cgattgggtt ttgtccaagc gccatttctc cattttccat agaaggtccg
    32041 tcagcgatga aatcgccttt ttcaacgaca tcaccaactt ttacgagagt gcgttggttg
    32101 taagcagtac ctgagtttga acgacggaat ttttggatgt ggtaaacatc caatgaacca
    32161 tcttcacgac gaacttctac cttgtcagca tctgcgtaag taactttacc atcatactga
    32221 gcaatcacag ccgcaccaga atcgtgggct gcttggtatt ccataccagt accaacgtaa
    32281 ggtgcctgag gattaatcag tggcacagcc tgacgttgca tattggctcc catgagggca
    32341 cggttggagt catcgttttc caagaaagga atacatgctg tcgcaacggc aactacctgt
    32401 tttggtgaaa cgtccatgta gtcaacaata ttagctggat actcttggtt gaccccttgg
    32461 tgacgtccca tgacaatctt ctcagcaaag gttccatctt cattcagacg agagttagcc
    32521 tgagctacag tatattcatc ttcttcatca gctgtcaacc aaacaatttc gttcgtgaca
    32581 acacctgttt cacggtcaac cttacggtat ggtgtttgaa caaaaccata tttgttcaag
    32641 tgtccgtaag atgacaagtt attgatcaaa ccgatgttag gtccttcagg tgtctcgatt
    32701 ggacacatac gaccatagtg agtgtagtgc acgtcacgca cttcatatcc agcacggtca
    32761 cgagtcaaac caccaggtcc taaggctgac aaacggcgtt tgtgagacaa ctcagaaagc
    32821 gggttgtgtt ggtccatgaa ctgtgacaac tgtgatgaac caaagaattc tttaactgca
    32881 gctgttacag gacgaatatt gataatttgt tgtggtgtca agacttcatt gtcctgaaca
    32941 gacatacgtt cacggacatt acgttccata cgagaaagtc ccaaacgtac ttggttggca
    33001 agcaattcac caaccgcacg gatacgacga tttccaaggt ggtcgatatc atctacacgg
    33061 ccaagtcctt cagccaagtt gaggaagtag ctcatctcag caaggatatc tgcaggagtc
    33121 accgtacgaa ccttgtcatc tgggttagca ttaccaatga tcgttacgac gcgatctgga
    33181 tcagttggag caataacctt gaatttttga agaacaacag gctcagtcac aacggctgca
    33241 tcgtttggga tgtagacaat cttgttcaag tcgccatcca aatggctttc aatgctttca
    33301 atcacgctac gagtcataat cgtaccagct tctaccaaga tttctccagt ttcagggtct
    33361 accaatggct ctgcaatggt ttggttgagt aaacgtgttt taacattgag ttttttattg
    33421 attttgtaac gaccaactgc tgccaagtca taacgacgtg ggtcaaagaa gcgagctaca
    33481 agcaagctac gtgagctttc agccgtctta ggctcacctg gacgaaggcg ttcgtaaatt
    33541 tctttcaagg cttcgtctgt acgagagtcc attggattct tgtggatatc tttttcaaca
    33601 gtgttgcgaa ccaattcgct gtcaccaaag atatcaaaga tttcatcatc acctgagaaa
    33661 ccaagagcac gaaccaaggt tgtaaatgga atcttacgag tacggtcgat acgagtgtag
    33721 gtgatatctt ttgagtcgct ttcaagttcc aaccaagctc cacggttagg gataacagtt
    33781 gaaccatagc ccaccttacc atttttgtct actttgtcgt taaagtaaac acctggtgag
    33841 cggaccaact gagaaacgat aatacgttca ccaccattga tgatgaaagt acccatttct
    33901 gtcatgattg ggaaatcacc aaagaaaact tcttgggtct tgatttcgct tgtttcttta
    33961 ttgatcaaac ggaaggttac aaaaattggt gctgagtagc tagcatcgtg gatacgagct
    34021 tcttctagcg tatattttgg ttccttgatt tcatatccaa caaattccaa ctccattgtg
    34081 tctgtgaagt ttgaaattgg caatacatct tcaaacactt ccttaagacc gtggtctagg
    34141 aaagctttga atgagtcagt ttgaatttca atcaaatttg gtaagtcaag aacttctttg
    34201 attcttgaaa aactacgacg ggtacgatgt ttcccgtatt gaacgtcatg tcctgccaag
    34261 atgattctcc tttgtaaata agttccaagc cttgtcaatc aggcttttct aatcgtcata
    34321 tggttgtaaa ccccttatca ccgtgtcctc ttgacgaatt ttcagaatct ttaagcctct
    34381 gttacaaatg ctcaaaatct tgaaaaaaag cacaaaaaga gcagctaaat ctgacttttt
    34441 cagaagattt aactgctgtg agccttgtct ggacaatatt tcagacaaaa cctacgacaa
    34501 atgattaccc atattatacc ctatttagct agatttttca aggggtttta gtaggttttt
    34561 ggtaaatttt ttcccataga aaacttggca tcacattcga atcacgctat ggtacaaaaa
    34621 actgaaaaaa ctattgactg aaaatcattt tcaaggtata ataataaacg ttaaggcggt
    34681 atagccaagt ggtaaggcac ggctctgcaa aagcttgatc gtcggttcaa atccgtctac
    34741 cgccttctat aacttgattt atcaggtttc aaatgaacag aaagcccaat ttgaagggct
    34801 ttttttattt tccctcgaat aaatacgtat aactttaaaa acttttggag cgagtttgtg
    34861 gcagagttct ttccatggca taattccctt ttgaaatcaa ttgaaaaaag cttcgtcacg
    34921 cctggtgaca aaagcctcta gtttattctg tttcttcttc tatttcgact tctgtgattt
    34981 ggacttttac cttggtaaca cgtccattct tcactttatc attggttaag ataaactgtt
    35041 tgttttggct aaccaattca tagctgagtt tctcagtcgt tggaatagtt cccactcctg
    35101 tcaaataata accagcgatg gtatcaacgt catcactttc cagttcaaca tcaaagtaat
    35161 tattgaaatc attgagggtc atagttcctt gaacaatgta ggtatcctcg ccaatctgat
    35221 gaacatctat tgctgctttg tccgtttcat catcaatttc accaacaatt tcctctaaga
    35281 ggtcttccaa agtcaccaaa ccagccatac caccgtattc atccagcaag attgccattt
    35341 gtctttgggt atttcgcagt tcttttagca agtcatccac aaaaatagtt tcaggtacaa
    35401 aaagtggatc ttgcaaaatt ctcttccaaa caatattgtc aaaaccgtcc acaaagcctg
    35461 ccttaaggag actcttggtg tgaatgattc caattacatt gtccttatcc ccatcataaa
    35521 ccgggatacg agaataattt tgttttaaaa tactttggat aatggcttga ctatcatcct
    35581 gaatatccac cataaaggca tccgttcgag gaaccataac ctctcgtgcc atcagttcat
    35641 cgagcgaaaa gacaccttgt agcatctcaa tctcatcagc atccaatgtt tcttcactat
    35701 ttgtcagcat ataggcaatt tcatcacggg tcatcttttc atccgcatca tcgaatgaca
    35761 taggagtcaa atggctcaag aaattggtcg aagcagctaa aagccaaaca aaaggactga
    35821 ctagttttcc gatcccaatg ataaccggcg ctatacgaat tgccaaggca tcctttagat
    35881 taagagcgat tctcttagga tataattccc caaaaacgat ggaaatatag gtcaaaaatg
    35941 ccaaggatag aaaagttgcc acggcttgtg ctgtttcgcc attcccaagc caagaggcaa
    36001 tcacacgtcc tagagtatta gttaaactcg cccctgataa gattgtaatc agggtgattc
    36061 ctacctgaat ggttgataaa aagtggttag gattttctag taccttcagc aggcggatgt
    36121 agcgtctgtc tccttcttcc gccttttgtt caactcgggc acgattaaga gaaaccatgg
    36181 ccatttctgt ggctgagaaa aaggcattta ataccgtcaa gataaacaat aaaacaaatt
    36241 gtagcaacaa attctgacta cttgggtctt ccatagttct tctcctaaaa tagtatctta
    36301 tcctttatta tatcacaaaa tttaatccaa tacatattat tttttcttac cgtaacttct
    36361 caaagtaact tccatctctc tcccaaaact ggaagttagt tttagaagtt gctatttttt
    36421 cttagtacct gttctagccc tgcttaaact agtaaaaaga actcctacat ccataagtga
    36481 cataggagtt taggcttatc ttttactgag ttacagttac ttctccagtt cggtaatcca
    36541 gttgaagtcc cttttgaaca ttgggaacta gaacattgaa ttccaattct ccatccgaag
    36601 acttggcttc aatctgtgaa gctgagggaa ctaaatcctc gtttgaagcg tagtaaaggg
    36661 ttacacggta acggacacgc ttgttttggt ccaaggcttt acgcaccttg ctttcatagt
    36721 agttttgacc agtcgaatac tcggcttgtg cctgatttgc ccaggctgtc tgaacagcaa
    36781 tgtttttagg attgcttgtt gaggcatcaa aaccatccaa accaccgatt aaggcatagc
    36841 ctaacaaatg acctctatcg actgcatggg tataagagcc ctttagattc ttgacctgat
    36901 gccaacctgg aggagtccaa gaagttgaac cattcccagt ttctttacga ttcttgtact
    36961 gacgagtggc cttagacaag agggcattag ctacggttgg aacagtttcc ttgcccactg
    37021 tctttgtttt attgtcagcg tagggcttac ttgaaacctt ggcatctaga tttgttttat
    37081 taccattgac gataaaagca cctgagccat tccactccag actccccttt atttgactct
    37141 tgactgcgtc tgttaagaca ctctctgcca atgcttgact aggagcttca gacgcttgtt
    37201 ttttctgact aagattggtt ttgggactat taggtgccga cggcatctgc ttgatataat
    37261 agctccctgt agacaaaagc aataacacta gcagtccgat tagtgtctgt cttgtttttt
    37321 tgttcatatt tctccttatc tttagaaaaa ggctggttct ccagcctaat ttcctgtaaa
    37381 tttatgaatc aattcctgcc attttgctgg agacaggata gcccatggat cttgaccctt
    37441 gcccaagatt ccataaccta ccattaaacc gattcctaga gccagagtac ctaaaatcag
    37501 tactatgatg actaaaagta aacgcttgac tacgtagctt gatttcttat tcatcttcat
    37561 cacttgcctc aatccgctga atcttagcac ctagctgcgc caacttctca tggaaaccgt
    37621 agtaacctct atccaagtga accaatttac cgaccacagt ttctccctgt gctaccaaac
    37681 ctgtcaaaat caaggctgca ctggcacgaa ggtcagttga aagaacttct gctccctgca
    37741 aaggctgtcc accaacaata cgagctgtat cacggataat ctcagaatgc aagcccatgc
    37801 ggcgcatctc ttctaggtgt tggaaacgat tttcgaaaac tgtctccacc atggttgatt
    37861 cgccttttgc aactgtcatc aaggctgtaa attgagcctg catatctgtt ggaaatcctg
    37921 ggtggggcaa ggttttcaca tgaacagctt ttagattttc tagttgagaa cgaacacgaa
    37981 ttccttcgtc ttcttcaatt acttcaacac ccatttcaag taacttggca atcaagggac
    38041 ggttgtgctc ccagacagcg tctcgaatca agacatcacc accagtcatg gcagcagcta
    38101 ccataaaggt tcctgcttcg atacggtctt ggactacatt gtgagtcgta ccatgaagtt
    38161 tctcaacacc agtaatggtt atagtctctg taccagcacc tttgaccttg gctcccattt
    38221 cattaaggag aatggctaag tcaacaatct caggctcacg cgcagcattc tcaatcactg
    38281 tcaccccatc agccagagtc gctgccatca tcaagttctg cgttgcacca acacttggaa
    38341 agtccatata gatatgagcg ccatgcaagc gttctgcctt ggcttcgatg taaccagctg
    38401 tctgactaat cttaaccccc atagcttcca gacctttcaa atgaagatca ataggacggc
    38461 taccaatcgt acaaccacct ggcatggata ccttggcatg acccacacgg gcaaggattg
    38521 gccctaatac aacgatggag gcgcgcatct tgctgacata cttgtaaggg gcttcctcag
    38581 tgatgtcgcc agtagcatcc accttgacaa gatgagcttc ctcatcaaag tcaaccttgg
    38641 cattcaaacc accaactacc tgattcataa taaagacatc cgacaaaatc ggaacattct
    38701 gcaagacggt ctttccttca cttgctagaa tagtcgctgc caacaagggt aagactgcat
    38761 tttttgctcc ctcgatcgtc acgcttccta ccagacgatt atcgccacct tgaaccacaa
    38821 ttttatccat actcgtttcc tttactcttg atttcataat aatcctctaa gcgcttcttg
    38881 ccacaaatga tacaggctaa taaagaaaga actcaggatg tagcctatga caatgctaaa
    38941 aaaggctact aataaacgaa cttttcttgt attctcatct gtcactttta aaaccttctc
    39001 ccatctaaca agatccttta aaaggtaaaa actcacataa ataaagagca tatgactact
    39061 tagagtgaat aataattgaa ccatttgact attataccat cttctctgtt tgtgcgctag
    39121 tttggaaact tcactcaaaa attagggatt gtttttcaag taatcaatcg catcttgtag
    39181 ggttttaacg ggcacgattt tcatatccgt cttgattgtt ttagccgctt ctagggctgt
    39241 ttggtagttg tttttcgcgt ccggatgcgc cttttgttct tcttcgctaa cagggttatc
    39301 aggagcaaag aaaatagcag cacctgccct agccgaagct acaaccttct tatcaatacc
    39361 tccaatgtct cccacattac catcgcggtc aatggtacct gtaccggcaa caatacgacc
    39421 attacgaaga tctgggtgag ctatttgagt atagatagct agactaaaca tgagaccagc
    39481 acttggaccg ccaataccag ctgttgaaaa gctaattggg acattgctga ttacctctgt
    39541 acggtcaatc aagccgattc caattccatt tttgccattt tccaaggtga taatctttcc
    39601 ttctgcagac ttggtttgcc catcctcttc ataggtgacc ttgacggaat cccctaattt
    39661 ttgagaactg acgtaatcaa tcaagtcttt ggaactatca aaggtctgat cattgactgc
    39721 tgtgactgta tcagagatat tgagaatccc tttaaaggtt gaattatccg tcacattcaa
    39781 aacataaact ccaaagtact tgagttcgat atccttacca gctgttttta gtccttgata
    39841 cttggccata ttttgcgatg tttgcatgta gaattgattg attcgcataa attcaacatc
    39901 ggaagaacca cctgtagtct cctgagcact acgaatatct gtaaaaggtg tcaaccaagc
    39961 ataaatcata tgagctaaag tggcatgttg aacaccaacc gtaacgaatt gataggcacc
    40021 agcttcctta tcttctgtgt catttatttt aaggacttgg cgaatatctt ccgaaccacc
    40081 tggaacctct atataataag gcaagggcac tacaaatgcc aagaaagtca caatcaaggc
    40141 cgcaatgacg tataagggcc atctaatctt ttttttcatt tcttatttcc tccaaaatac
    40201 tctcgggaac atagcaggca atatcccgac caaacttcaa aagctctcta acgcctgatg
    40261 aactgatata gagatgttca ggtcgactat gtaaataaat agtctctata tcagaagaca
    40321 gctgatgatt gtagtaatca aaactggctt catattgcaa atccgacgca ttcctcaaac
    40381 cacgcactag acaagtagca cccaatcttt ttgcaacatc gaccaccaat tcatcatgag
    40441 aagccacgac ttcaacattt tccaaatgtc ccaaagcctt ttctagcccc cgtttacgat
    40501 tttcaagagg gagaaatcct tgtttgtggg gattaaaaaa aatacccaca taaagcttat
    40561 caaaaagtct gctcgcccgt tcaatgatat ccagatgccc atttgtcatc ggatcaaatg
    40621 agcctgtgaa taagccaatc ttatctgaca tagactgtca ccttactaat tccataaatc
    40681 ttttccttcc agatacccag acaggcaatt tcttctggaa gttcaacggc tttatccgtc
    40741 tcgcacacaa ccataacatc ttcagaaaaa agctctctct cagccatttt ttcaatatct
    40801 gctacgattt gttccttggc atagggaggg tctaagaaaa cgaggtcaaa ttccccagat
    40861 acctgttcca atgccctttc tgcatccatc tttaggagtt gaaattttcc aacttccttg
    40921 gtcatctgga tattttcagc cacgatggtc tgagccttac ggtctcgctc caccaaaaca
    40981 gcactggaca tgccacgcga tactgcttcg atagataaac caccactacc tgcataaagg
    41041 tccaagactc gtcccacttc aaagtaggga ccaatcatgt taaaaatggc tcccctaacc
    41101 ttatccgaag taggtcttgt cgtcttgcct tctagtgtct tgaggggacg tcccccatag
    41161 attcctgata cgattttcat actgtttatt ataccaaatt atagacaaaa agagaaagaa
    41221 aaccgaacct tgcggttcga ttctctacaa aatattttcg taagtatcgc ggacttcttg
    41281 aggccaaaca cttgtttgca cttctccgat gtgtctcttg cgaagtagga acatggccat
    41341 acgagattgt ccaattcctc caccgattgt caatgggaat agaccattca acaaagactt
    41401 gtgccattcc aattccaagc ggtcttcatc acctgtaatt tccacctgac gtctaagagt
    41461 ttcttcatct acacgaattc ccatagaaga caactcaaag gctccaccta aagactcatt
    41521 ccagacaaga atatcaccat ttagaccctt gtagccattc tcagactcgc ttgtccagtc
    41581 atcatagtct ggtgcacgtc catcgtgcgg tttaccatct ggcaactcgc caccgatacc
    41641 aatcaaaaag acggctccaa attctttaca aatcgcattt tcacgttctt tcggtgtcaa
    41701 gtctgggtag cgttctacca attcttctgt atggataaag gtgatttgtt ttggcaagat
    41761 agactcgatg tcatagcggg cttcaacagc tagctcagtc aggcgaatag ccttataaat
    41821 cttctcaact gtttctttta gataaacgat gttacgctta ccatttggga taaccttctc
    41881 ccagtcccac tggtcaacat aaacagagtg ggttgcatcc aaggaatcct catctggacg
    41941 aagggctttc atgtggacaa agagaccctc tccttcacca aagccaaaac gagccaaggt
    42001 gtggcgtttc catttagcaa gtgagtgcac cacttcataa gtagcatcag ggatttggag
    42061 aaccttgacc gatactggat tttccacacc agacaggttg tcctgcattc cgtcaccgac
    42121 cttactcaag ataggacctt gaacttcgac aacttctagc ttatctttca aatactgggt
    42181 aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg ataaaacttt tcttcataga
    42241 caactcctca aaaatttaat aaacgtatta tacacctatt tccaagaaaa gaaaagagaa
    42301 aatttaaaaa aaaatcagtg tcactcaaaa cactgatttc atagaccttt tagtcattgc
    42361 gaccaaagat acgtagaata cttaggaaaa gattgataaa atcaagatag atgctgagag
    42421 ccattgacac cacccagcct gtcgctacac gaccttgtga ttgttcatag gcgaggcgaa
    42481 tcttttggtt atcccaagca atcaaccctg aaaaaaccaa aaccatggct acgctaatca
    42541 tataatcaaa gaagccacta gccaagaaaa tattgactac catagcaatc agtaaaccaa
    42601 tgagagctgc catcattgct cgaccaatcc cactcaagtc tttcttggta aaaataccaa
    42661 ctgccgccat gacaaagaag agaagggcgc tcgatacaaa ggcagataaa actgtacccg
    42721 gagtatagaa agccaccaca aaactaaggg taaagccgtt taaaacggag taaagtaaaa
    42781 atactggaag agcagctgga ctatttcttg aagccatgct actggcaacg aaaaccaaag
    42841 ccaactccgc aaaagtagca atggtcaacc agagacgccc ctgcatcaaa aagtaaacca
    42901 actgagactg aaagaccgtc aacataaggc ctgataccaa agcagatagt ccgattccca
    42961 gaccaacaaa ggcataaacc ttagcgtaaa attgattgag acctgcacgg tcatgtataa
    43021 tagtgtgatt catccatttc tccttttctg tgaacatctt tccttgatta taacaaaaaa
    43081 agttaaaatt agcttaaatg gaagattaaa ataccggctg caaccgcaac attcaaactc
    43141 tcggcctgcc ccttcatgct aatatggacc aactggtctg cactttcagc cataagggga
    43201 ctaattcctt gaccctcatt tcccataact agtacaaaat tttctataga aggcagttct
    43261 ctgtaatcaa cagaatcttt agatagggtt gttgctagca ctgggatagc taccttttta
    43321 gtttcgtcaa gaagcgcttg actagtcatc cggtaaatgg gcagatggaa atgactacct
    43381 tgcatggaac gtagggtttt gagactgtag atgtctgccg acttatctga aacaatcact
    43441 cctgtaaaac ctgctgcatc cgcagttcga atgatagttc ctacattacc aggatcttgc
    43501 acatcttcca aaaacaagaa cttgccctga ctcaaatcag cttgtcctac ttcttctttt
    43561 tgaaccacgg caacaattcc ctgtggagtc tgagaatccg ccaaatctag caaaatatcc
    43621 tctgacaccc agacagtttg cgaaaaagta gctaactgat ctcgataatt ttctagggca
    43681 aagattttct caatcgtcac tccagcttgg acagcttctt caaacaagtg ccagccttca
    43741 atcaagtagg cagacttgcg gtattttttt tggcgtaatt tcttggcatt ttttaccaca
    43801 gaattggctt ttgaggttat aatagtcata gaaatattat aacacaatca aaggggtttg
    43861 gtatgcaaaa ggttagaatg attgcccaag gtagggtaca gggagtcggc tttcgttggg
    43921 gtgtttacag cttggcactt gaaattggtg gcatcacagg tcgagtatgg aataacgacg
    43981 atggcacagt ggaaatctta gcccaagcag actcatctgc tatcatggca aaatttatcc
    44041 aagaaatccg aaaaggaccg acaccttttt caaaagtaag ctacttagat gtcaaactaa
    44101 gcaactttcc tccctactct gactttaaaa tcgcaaatta ggtctccaga actattgtat
    44161 attttgtaaa aaaacagtag aatagaaagg tataattttt aaagaaggaa taaaaacagt
    44221 gaaatctatt aaacgttttg cactctcagc tatgggagcg gctatgttgc ttgtcttgac
    44281 tggttgtgtc aatgtcgata aaaccacagg tcagccaaca ggatttattt ggaataccat
    44341 cggagcccct atggctgaag ctatcaagta cttcgctact gataaaggtc taggctttgg
    44401 tgtcgctatc atcatcgtaa ccattatcgt gcgcttgatt atcttgccac ttggtatcta
    44461 ccaatcatgg aaggcaacgc ttcactctga aaagatgaac gccctcaagc acgtccttga
    44521 gccacaccaa acgcgtctca aagaagcgac tactcaagaa gaaaaactcg aagcccaaca
    44581 agctctcttt gctgctcaaa aagagcacgg tatcagcatg tttggcggtg taggatgttt
    44641 ccctatcctc cttcaaatgc ctttcttctc tgctatctac tttgctgccc aacatactga
    44701 aggggttgct caagcaagct acctaggcat tcctctaggt tctccaagta tgattttggt
    44761 tgcctgtgct ggtgtccttt actatcttca atcgctcctt tcacttcacg gagtagaaga
    44821 tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg agcccactca tgatcgtcgt
    44881 cttctccctc ttctcaccag ctagtgtcac actttactgg gttgtcggtg gtttcatgat
    44941 gattctccaa cagtttatcg tcaactatat cgttcgtcca aaacttcgca aaaaagtccg
    45001 tgaagaacta gccaagaacc caccaaaagc aagtgctttc tctaaaccaa gtggacgaaa
    45061 agacgttacc cctgaacaac caactgctat cacaagcaag aaaaaacaca aaaatcgcaa
    45121 cgctggaaaa caacgttcga gataagaaga aaaaggctta gctgatttgc taagtctttt
    45181 tgcaaatcaa aagcccgatg tttccatcag gcttcttttc tatccatgta cacgtttcat
    45241 ataatcttga taactttcgg tatccatgag ttttttagcg ttcttgacgc gatctgctgt
    45301 tggtggtttg actccttcga gggaatatgg aattccaagt tcacgccact tgaactcacc
    45361 catggtgtga taaggtagaa tttcaaactt atcaacattt ttgagggtct tgacgaactt
    45421 accaagttca atcaagtcat catctctgtc tgtcaatcct ggaactagca cgtggcgaat
    45481 ccagacaggt tttccaatat ctgatagata ctgggcacaa gccaagatat ttttattggt
    45541 ttgtctagtg acaatcttgt gctgttcttc gttgatttcc ttgatatcca aaagaaccaa
    45601 gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa cgtggtttat tacggaaagg
    45661 aagagcacag gtatccaagg tacagtggat tccttgttcc ttagccttgg tgaagagagc
    45721 aatcaggaaa tcaatctgca agagagcttc tcctccactg actgtaatcc cacccttatt
    45781 tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca tcatctaccg tccgttcacg
    45841 tgacttattg gactccatag cccaagtgtc tgggttgtgg caatactggc aacgcatgtg
    45901 acagccctgc aaaaagacaa taaagcgaat accaggccca tctactgacc caaagctttc
    45961 tgtcgaatgc accattcctg tcacttgtcc ataatcaatt gtttcttcag acatatcgtt
    46021 accttccttg aaaacgtttt atagttttat tatatcacga cttgaaggaa aaacaagatt
    46081 tttgcctatt ttttagaaag caatctgttt ttcaatttca ttttcaatct attatcagat
    46141 tattcttcaa aatcgaagcc atataaggtt gcaaaatagt cctcagggcg ctctgcacgg
    46201 cggatttgac gggctttacc ttcttcggta tagaggattt ccgcagaacg taatttggca
    46261 ttatactggt agcccattga aaatccgtgg gcacctgtat catgaattac cagcaaatca
    46321 ccgatttctg tatgaggcag ttcgcgattg actgcaaatt tatcattgtt ttcacagagt
    46381 gaaccaacca catctaccgc ttcagctggt ccatctggat gggtcacgtt gctaatatga
    46441 tggtaagctc cgtacatagc tggacgcatg aggttgactg ctgaggcatc cacacctaga
    46501 taggtacggt aggtttcctt cttatgagtc actcttgtga ctagagcacc gtgaggtgcc
    46561 agcataaaac gacccaattc ggtgaaaatc ttgacctgac caagacctgc tgacgtaaga
    46621 acttcttcat acaccttacg aactccctca ccaatcaagg cgatatcgtt cggctcctgg
    46681 tctggacgat aattaacacc aataccgcca gaaagattga taaagtctag ccaaatgccc
    46741 aacttttcct tgatttcaac agccagttca aagagctgac gagccaactc tggataatag
    46801 agatgggtca cggtattgga cgctaggaag gagtgaatcc caaaagtctt ggctcctttt
    46861 tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg tcatgccaaa cttagcctcc
    46921 ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc ctccaggatt ataacgacaa
    46981 gagatgattt ctggaatgcc tgctactctc tccagatgtt caatatcttc aaaggcatcc
    47041 aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt ccttgtctgg cgtgttgttg
    47101 gaagagaaca taatctcaga acccagaaag tccagtttat ggctcatcaa aagctctaca
    47161 taactagagc agtccacacc acaaccttct tcttggagaa ttttcaaaat agctggagtt
    47221 ggagtagcct taactgcaaa atattcctta aagcccttgt tccacgaaaa agcttggttg
    47281 acggctcttg ccttctcacg aatccccttc tcatcataca agtgaaaggg agtcgggaac
    47341 tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg gtgttttcat aagcttcctt
    47401 ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa cctttagttc tatctcttat
    47461 ttatcttcgt caaagatatt gccaacctca acatcgatgg cttggttctt gacatcaata
    47521 ttagttacct tcaagagtga cttgtagtca aactgctttt cacgttcttc ttgggcattg
    47581 tccgcaaaga ccgctacacc tgccagttct gagtcgaact cgcgcaagag actaatcata
    47641 ccgttgaccg ttccgccacc tttcaagaag tcatccacaa tcaagacacg gctacctgcc
    47701 ttaagactac gttttgaaag gaacattttc tcgatacggt caccacttga acctgaaaca
    47761 tagttgacgc taacagttga accttcggta attttcaggt cacggcgcac aatgacaaaa
    47821 gagacattga ggacattggc aactgcattt gcaagtggca cacccttagt tgctacggtc
    47881 ataaccgcgt caattttttg gtccataaag cttttggcaa taatacgacc aatatttttc
    47941 aagatggctg gtgtgctaag caaatcagac agatagatat aaccacctgg caagatacgg
    48001 tcactttctg acaacttggt acgcaagtct tcaaccattt ccttagcatc ctgactcgaa
    48061 atagacggtg tgaagatgac acctccgcca gccccagtca ctgtctggat atgaccgatt
    48121 tcaatttcct caaaggcgcg tttgataatg acgatatctt ctgagatgga tgatttagca
    48181 gactcatact tttcagcaaa agtattgaga ctagttagtt tataaggatt attaatcaaa
    48241 tagttggaaa tgacaaccat ccgatcactt cttcttaatt tcatttctat ttcctattcc
    48301 atttttattc aaaaaatcaa aaagcaaact agaaagctgg tcgctggtgg ttcaaaacac
    48361 tgttttgaga ttgtcaatag aactgacaaa ccctgtaata tacctgcata tatacatacg
    48421 acaaggcgat actaccctag tttgaagaga ttttcgaaga gtattcattt ttgtctttta
    48481 cttattatac catattcaca taaaaaaacg aacattctta tcctaaaaaa tgctcatttt
    48541 tcttaaatta ttaatctaaa tctggtttat agaaggaacg attatccata gcgaagattt
    48601 tattggtcat ctctccttta tccaccaaag caagagctgt tgacatcatc atcatgcttg
    48661 catccagatt gtcaatcata tggataatct ctgcttccat aatgcgtgga cggactgggc
    48721 ttccatactc aagcaagccg tggtgactga ggatgacatg acgaagcaaa acgacttctt
    48781 ccttggtatc atcgatgccg agttccataa ctgtcttggt aatttcgcta tcaatgagag
    48841 cgatatgtcc aagaagatta cctcgcactg tgtactctgt ctggtctggc cccgtcaact
    48901 cgatgacctt agctaagtca tgcaacataa tccccgcata gagcaggctc ttattgagct
    48961 gaggataaac ttcgctaata gcgtctgcca aacgcaccat ggtcgccgta tgataggcca
    49021 agcccgtttc aaaggcatgg tggttggtct tggcagctgg ataggagtag aattccttat
    49081 catacttggt gtagagattt cggacaatcc gttgccagac aggattttca attttgaaaa
    49141 tcatttgcga catgtagtca cgaatttcct tgacatcaac tggtgacttg accttgaaat
    49201 cggctgggtc attgggttca ccagcttgag gcaggcggag agtaatttga ttgacttgag
    49261 gggtattgtt ataaacttct cggcgtcctt tcatgtggac aaccttacct gcggtaaagg
    49321 cctcaatgtt atgaggttgg gcatcccaga gcttcccatc aatctcgcca ctatcatctt
    49381 ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg cctcaggtca gctgatttga
    49441 ttaggtaaaa gccttcaaat agctcatctt ttttcatgtg actaatcttc atattcttcc
    49501 tcattttctt gaaaatggag tagatcaagc gcaggctcgc cttctgacaa ctcaatgtga
    49561 cggagcgtcc gctcgatagc tatggtacga cggtttaata attcatcaat attgccagag
    49621 gcatgttgga gatgtttttg tgccttgacc agaataccac caaacttgcc aaactcggtc
    49681 ttgacactgg caagagtctt gctgatatgg tcggcactct tttggatatt aagggtcttg
    49741 aaaccaactg atagggagtt aagaagggct gatagggtac ttggtcctgc aacgataatc
    49801 tgttcttccc gtctcaaatc atcaaagaag accggattgc gcacaatctc tgaataaaga
    49861 ccttctgtcg gaacaaacaa aactccaaaa ttggtcgtcc gaggcggtgc tatgtacttg
    49921 ctcttgatat ccttggcaaa gcgcttgacg cttgctagga gtgacttacg acagcgttca
    49981 atctcatcct tgtcacctgt ctcataggct tcttccaagc ggtaataatc tgccagtgga
    50041 aacttagagt caattggcag atagacgtat tcttggtcgc cttgtccggg taacttgatg
    50101 gcatactcca ctcgttcact agagttttca accgttgcgt attctcgttc gtactgggca
    50161 ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt ctcccagaat ccctcgcgtc
    50221 ttggttccag agagaacctt gttaagagct ccgacatcac gggcaactgt ctgcatttct
    50281 ccaaggccac gattgacaga ctccagttgt ttagaaactg tctcaaagga agcctgtaag
    50341 cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct ggcgcatttg ttccaaacgt
    50401 tgctcatttg attcctgcaa ggcttggaga cgttggtctg tcttgtctct agtttggagg
    50461 agattatctg tcatttcttg acggacttgg gtcagacctt ggtgcaattc aatccgcact
    50521 tcttgcaaac ggtcgctgac aaccacttcc aaatcttttt ggtctaactg gctggcttgt
    50581 ctggcttggt caaagcggta atccaactgg tctgacaaat gatctgcctg atcctccaag
    50641 ctcttactta agtgtttctc ctgcctatcc tgcctttgcc aaatcagaaa gagaccagct
    50701 aggttggcaa ttaataatag aataagtaaa ctttccatcc tacctcctgt ccttgctatg
    50761 cagtacgacc acataaccat ctgggcaagt taccgacact tccctatcta tatattcgtt
    50821 agaagcgtac acttttttaa agaaaaaatt ttcctctgtc aactcatact tggctccaag
    50881 aatagtcagc tggctatccc gaactggcat aaaggctaga tagtcgtagt ctgaacgagg
    50941 ttctagctga ctggtccctt ctggacaata agtaatcaag ttttgcccat cctcaatttc
    51001 tatttgatgc atatagggtg ccaacttagg attgctaggc agaaagacat tggccaacat
    51061 atggtcaata cggccaccca aggcaccgaa aatagtaacc tgagcctgag gatttttctc
    51121 aaagatggtt aagagagcca attccaaatc ggtatcatct ttttctggtc gggcttggac
    51181 aaaatgctgg gcacgttttt gaatcacctg tcgctcttct tcggtcacag aatcaaaatc
    51241 cccaactgct agagcaagaa gcaagtcttc ttccaagacc cagagcgagc ctcgatccac
    51301 cccaacaaaa gcatcaaaat ctgtccgata atgaccgcgg tctccgcctg caaaaacggc
    51361 aaccctagtc cagttgtttt ctgagagttt gtactcgctc attgacatct cccttaaaga
    51421 cataggaacc tgctacaaaa acggtcgcac cagcttcttt ggcttgggca atagtttggt
    51481 catcaatccc accatccact tcgatttcaa agttcaaacc tttttcctca cgaagagcaa
    51541 ccaactcacg aaccttatcc atggtttctg gcagaaaggc ttgcccacca aaacctggat
    51601 taaccgtcat gactaaaact tggtcaacta gatgaaggac gtgcttgatg gcttcaactg
    51661 atgtgccagg attgataacg actgaaggct taactccgag tgaacgaatt ttttggaggg
    51721 cgccatgaat atgaggcgtt gcttctacat ggatactgat gatgtctgca cctgcacgcg
    51781 caaaatcttc cagatgatgc tcagggtttg acaccatcaa gtggcaatcg aaaaccatct
    51841 tactatgagg acgaaggctc tcgaccacac ctgcaccaaa actgatttgc ggtacaaaat
    51901 gactgtccat gatatcgata tgggcatatt ctgccccagt tgcttctaga cgtttgattt
    51961 cacgttcaaa gttggcataa tctgctgcca gaattgacgg agcaatcttg tattgagaca
    52021 taggtttctc cttattttgg aatttttttg ctgacttttt tataggtttc tctacgattt
    52081 tcaatttcac taaggaattg caggtaattg tcaaaacgga aggttgcaat aacaccctct
    52141 tcaacagctg gtttgacggc acaagacggc tcatgggtat gggtacaagt acggaactta
    52201 caatctcggc taacagtagc aatctctgga aaggcctgat tgaggtcttc agcccttgat
    52261 acttcatagt ccagagatga aaagcctggt gtatctgcga ttttaccccc gttgagattg
    52321 taaaaactaa cagctcgagt ggtatggcga ccgcgaccta gactgtctga aatttctccc
    52381 gtttcaagat tgaggtctgg tgcgatttta ttgagaagag ttgacttccc aacacctgtc
    52441 tgccccataa agaccgtaac cttgcctgtt aacaaagaca ggagttcctc tttactggtc
    52501 acaaagtcat agccgatgtc accataggtc tgctggtaaa aatccagttc tcccctatct
    52561 tccaacaaat ccattttgga aatatagaca atgggatgga tgcccttgtg ctccaaaaga
    52621 accaagaaac gatccagcaa attgctgtta aaatcaggtt ccttgacgga catgattact
    52681 acagcttgat cgatattgac aataggcgga cgaaccagac tgtttttccg ttcgtgaatt
    52741 ttgaggatat agccttctga attttcctcg gcagagaaat ctacccagtc cccaacataa
    52801 ggggtatggc cttttttacg gaaattccca cgcgcgcgtg tttgataaac ctggccatca
    52861 ctctccacat agtagaaacc tgccaaggct ttaatgattt gtccctgcat cttagagtcc
    52921 ttgcccttta agtgcgtctg ctagaccggc aaattctgcc aagctgagag cttccccacg
    52981 cacacttggt gacaagcctg cctggtccaa agccttggtc agcttgtcct tgacctcttc
    53041 agtcttacca aagtaacctg tcaagttatt ccacaaggtc ttgcggcgat gggtaaaact
    53101 agccttggaa accttaaaga aaaagttctc atcttctact gctacggctg gctctggacg
    53161 acgcaccatt ttcaagatgg ctgaatccac atttggcgct ggcacaaaga ccgtacgagg
    53221 cacgataaag gcaaccttgg ctgtcatgta atactgcacg gcgatagaca agctaccgta
    53281 agccttggtg ttaggctggg ctgaaatgcg gtccgctact tctttctgca tcatgaccac
    53341 aaactcacaa aaaggaatgc cactctcaat caagtgcatg agaataggcg tcgtgatgta
    53401 gtaaggcaaa ttagccacta ccttgattgg caggttagga tttttaaaat tttggatatg
    53461 ttgcgccaaa tcaaccttga gaatatcttc gttaactacg gtcacattat caaaatcacg
    53521 cagagtatct gccaaaattg gcatcaaacg gtggtcaatc tcaaaagcca tgacttgggc
    53581 tgcacgctca gccaaaaatt ctgccaaggc accaatacct ggcccgattt cgatgacatt
    53641 gacctgatca tcaatttcag ccgtatccac aattttttga aggatattgg tatccgtcaa
    53701 gaaattttgc ccaaaggact ttttaaaggt aaaaccgtga cgctccaaca ctgccttggt
    53761 cacgctataa tctgcaattc tcatctattc tcttttctat tatctgttac tactattgta
    53821 acacattccc cttgtatttt gggaatgaaa atcataccaa aaaactatct ttcctcatga
    53881 agaaagatag tcttggaaat ctttaaagag ggacttagtg cttctctcga aacatacgtt
    53941 catactcttc gaaaatctct tcaaaccacg tcagcttcac cttgccgtac tcaagtacag
    54001 cctgcggcta gcttcctagt ttgctctttg attttcattg agtatcaaaa aaatcagctt
    54061 cttgataact tcgattttcg ggtagggtca aatccacatc ctcctccaca tcatccactg
    54121 tcagttcaac cgtctgaggt aaatttttca aacgataatg cttttgcctt tgcccttcaa
    54181 tactagcaaa atcaagcaaa tagccatgca ctcggatttg aaccaaaagg agatgattgg
    54241 tcatattttc catgatgagg atatcttcta aaccacctct ggcactagga taatcagata
    54301 ccctgcgaat acggattttt tcacacatga gcaagtttcc tcatatcaat gatttcatca
    54361 gccttattcc agactagggg attatgggtc gcaatgatga taattcgatt ttcatctttc
    54421 aaatccacca agagattcat aacctcctct gaattttcag gatcaagagc tgctgttggt
    54481 tcatctgcca aaatcaaggg tggatttttc aaaatagtct tagcaagggc aactcgttgg
    54541 gcctctcccc cagataaagt ataaattttt tgttctaaat ccaaataccc tagattaact
    54601 ttttctaaag cccccacttg cctttccaaa cgttctactt ttgagatttt ctgaccaaca
    54661 aaacccaaat ccaaattttc tttgattgat tggttttcta agaggccgaa attttgaaag
    54721 agatagccca tctggtctcg aaaatactca cgagtaggaa tggtttttaa atctttcccc
    54781 tgatagagaa cccttccacc atctatcttt tctagctttc ccaagatatt cagcagcgtc
    54841 gtctttccgc ttccactctt tccgattaag gcataaacct tgcccttctc cagcttgaga
    54901 ttcaaaccag agaaaatcgc gcggtcatta aatttctttt ccaatccttg aatatcaatc
    54961 atcttatttt cctttcaata ctgccatgct accagcttct tcttttttat cctgccttac
    55021 taaaatcaag agggcgttaa gcgtaaacaa agctacaact agagcgctaa tcaaaccatc
    55081 tcttgtcaaa atactagata ggactaggcc aagcaagaga actcctcctt gcgccagtaa
    55141 atacttgcca tgaagctcat agattgtcat accagcaaga cgtttaatca taagttcccg
    55201 tctgaactgc tcaaaataga gaagattcat ggaatcaaat aacaagatag ccgtagacag
    55261 ggtcaaaatc gtcccaataa ggagagagta aaactccacc cgtttgtcat ttagtacctt
    55321 ggcaaaaaat agctggcttt ttaccaagta agaaaccttg tgatacagac cttgctcttt
    55381 tagagctgtg atgctgtctc catatcgatc tagtttcaag gcactattag ccgtagttcc
    55441 ccacaacatc cctgcaacag gtcttgttcc agtcgcttgc ggcgttagaa ctacaataat
    55501 cggatctttt aggtactggc gtgttgtctt gtacccatca ttatagagga aacgttcctg
    55561 tcctgtttct gtaaaagcta gccttacctg tgggaggtag tgtttctgac tcgtcacttc
    55621 tacactttca gatgaaaagt tttgcaggta atctgtaaac aatccttggt agtaggcaga
    55681 ctgctctcgc aagctctcag gcaagatcag cccaaactct ccctcagaca agttttgcat
    55741 cttgtccata aactctgaag aaacggtaat cttttcttct atcagatagc gcggcgagac
    55801 atagataaca ttccctaacg gtgtgtagtc actgagacga ttgccatcta ggtccacttc
    55861 tgctccatct gagaaattgt caacattgct cataatataa aaagagtctg tattggctaa
    55921 ccgttcttca gtaaatgtct gccactcacg attatcctta cgcgttcctt cttcatcggc
    55981 aaatgcacta gaccaaccaa aggatagacg gtaacggtct gaggactggc tccatttatt
    56041 gctagctctc tccatttcct gcatttcacg gtagtggggt aggagagctg tcgcactcga
    56101 tccgaccacc aatacagcta agagttgccc caccatcatc aatgtcatca tacgtttgag
    56161 agggagtttc cctttcaata gatccaccag actattttcc tgtaaaccaa gtagatagac
    56221 gacacttagt aaggtagaaa tccctgccaa ggtcaatcca taaagtagaa gagcaatgat
    56281 gaccagttgt accgttgcca taaacaaggc accttgatac cagagaatcc ccaatcccaa
    56341 aagactggat accagcactg agcagataag ctgtctcaca tcttctaaca ctggtctgag
    56401 agcaactcca aacaagctct caccagctat taagcgaatc cctgcctgac gaagggattt
    56461 gatccgataa atcagggtca gactcataaa ggtcagcaga aaaatagcta aactcagtag
    56521 caccataggg gtggccgcca atagtaagac tatcgaaaat ggatcttctc cattcgaaac
    56581 aaagccttga taaccaagct ctttcaaggt ggtctgtaag ctcactccat ccaaacttcc
    56641 tgacacaatc aagtaagacc ctaataaatc actcgtttct gcactctcct tggaggaaat
    56701 ggtcagacct tctggaagct ctccctcacc ataagtggca taggtaaaga gtgtttctcc
    56761 agcttcattt ggctcaacga ttcgacgggc gatgagacta ttatgctcta ccgccaagtg
    56821 actcaaagcc tctgtcacct cttcgcgact agctactggt tgatttatca tcattcctgt
    56881 cacatcaaca gaaggatagt taccaaataa aatctcttct cgatggtcaa cggaagttat
    56941 caccatataa agcgatacca ataccattga aatcaaaata aataaacgtt tcatcatttc
    57001 ctccaaaaag ttacttggtc acttagtgag aaggtgacca agtaaagcta aacaataggg
    57061 ctataccatt ctaaacatta tagtagaatg caactttctc tccccaagaa gtacgaatcc
    57121 atgcacgaga agtccctcca gcaccagcat atcccttgtc agatgaacca gtttttctgc
    57181 taacaactgt tgaactatgg tattttgaag ggtgatagta gtttgagtaa gcaccaccgt
    57241 tacctgaacc ataagtccaa acaccacctt ctgggtattg aacggctgca gaggcaactg
    57301 atacacctcc acctaatgtt gctgcaatgc tcgctacaag agctaacttt ttaactgttt
    57361 gtttcatatt gatactcctc tatttttgat tacaagattg ttgagttact tgctcctctt
    57421 tccattatca acgttgatac tattatatta ccaaatgata ttctaaaatt atttgttttt
    57481 ctctaaattg tcaaaatagc accctgaaat gaacttttat agtcattata ctccatcttt
    57541 atcacactat caaggacatc aatgtcctta aaatctaact atttcatatt atttttagct
    57601 tatatctaaa aaaacagttc taaagacgaa ctttagaact gttttgatac gaggacaagg
    57661 acatttttgt cactgattca ctatgtttat aaatattttt tgacatcctc ttgccattcc
    57721 tctgtcaatt tctttactag aaatccatct ccaattagct tcgcaaatgt tttagaagac
    57781 tgataaaatg attcagctaa actaaaatct ctttctactc ttaatgcttg cttccacaaa
    57841 aacataaata caagaggttt cttttgataa tcttgagttt tatccataat ttcttgtaaa
    57901 cacgatagat aatcattaaa acaatcagtt actcctacct tttcaagaca acacattcct
    57961 gaaataagag tatctctaat tataaagaag ttttctaatt tagttacctt tttctgttcc
    58021 aaaagaaaga gcattagctt ttcgatttga tttataaatt tggcaagatc ttttctaatg
    58081 agcatttgat aaaaaaacaa acgaatcaac aacatatcat ttgttgaata aacttctttt
    58141 tctatgatct gagacatatg ttcctcaagt attaactctg catattcagg ccttctagtt
    58201 ctagaagtat ccaaacacgc ctgcaatact tcacatgcta attgttcttc tttaggaaga
    58261 ttatcaaagt atgttttata aatctcttcc aaacacgctt ctttcttatc atactcctct
    58321 tctttaccat agattggttc acgtaaaatc tggtatttca attctaaata agcagaagga
    58381 agagctgaaa aatccggcat aaggctataa actggaactc ctagccggcg agcaatatag
    58441 gctaacttgg gcaaactcgg ttgcgaagct ccactttcaa ttcgcgacag ttgacgaact
    58501 gtcagttctt gctcatctcc acaaaaatct ggacgactaa ttcctttttc tatccgaatc
    58561 tctttaattt tttgaccaat taacatcaga cgcctcctct tctacctgct tcgaaaaata
    58621 ctgtgaaact taaaaaattg taacggctac atctttccta ctcataagat ttcatagctt
    58681 cttccacttc tgccaaagta accccaaaca actctaggcg tttgaggagt tgcttgccat
    58741 tagaatagcc gattcggaga gtctctccga gatattctct acgcttacgg ctgtctgccc
    58801 ctgctagaaa accaaggcga atcaagtcgc tacgactaat gtcaaactga ctctcatgtt
    58861 caaattgttc tgtcacctga gctagagccg ttttcaggtc ttcatagctg gcatgctcaa
    58921 ttcccagaga acgccccttg gtcttggact tgggaacagc ttcatctcgc ttgagaaagg
    58981 catgctgaac tgttggaatg gccgtcataa tcatgcgccg aatccgctcc ccattaaaat
    59041 ctgggtctgt aaagacaatg actccatgac gttggtgtag acgctgaatt cgctctatat
    59101 cctgatcatt gatggcagaa cctcgtgtct cataggtctc cacatcgaaa taacgcttga
    59161 gattgaccgt atcatagcga ccttcaacca cgataacttg agaaattttc tctttcatta
    59221 cttgctgtcc aatccaaaaa ttcgttctgc atttgcagtc gttgctaccg ccagctcttc
    59281 tgtcgtcata ccacgcaagt cagcgataaa gtcgaccaca tagcgagtat aggctgtttt
    59341 attttcacga ccacgcttgg gtacaggtgc taagtaaggc gcatctgttt ccaccaacat
    59401 cttgtccaaa ggtaactctt tagctgcttc ttggaggtca gttgccttct tgaaagtcac
    59461 cactcctgag aaggaaatgg tcataccaag atccacaaac ttctctgccc actcaagcgt
    59521 ccctgaaaat gaatgcatga taccaccacg aggaccaacg ccctcactct tgataatctc
    59581 ataggtatct tccagcgcat cacgggtatg gacaacaaaa ggcaaatcca agtccttaga
    59641 tagctgaatc tgacggcgaa aaacctgctc ctgcacctct ttgggcgctg tcatccaatg
    59701 gtagtctaag ccaatttcac ctaaagccac aaccttggaa tgttttaact tatccaacaa
    59761 gtaagcctca acttcctctg tataagtacc agcttctgta ggatgccaac caatagtcgc
    59821 atagagctgc tcatactcat ctaccaactc caaggcacgc tcaatcgtcg gtttatcaaa
    59881 accaacaata ttcatctgta tcacacccat ctcagcagcc aaggcaattt cttctgcctc
    59941 acgacctgca aattcttcta cattcaagtg tgtatgtgta tcaaaaatca tctcttctaa
    60001 cctcgttttc tatcttctat tataccaaaa aagaggaggg gcacctaatt tttcggtttc
    60061 ccctcctctc ttcaatagag agctattctg ctatcttttc tatccgatat tgcccatctc
    60121 ctattccaca gttagagaca gaagagattg gctacattga tagaatattc ctattcagct
    60181 aaagtatgtg attatcttgg gttctcactt ttctcaccca tcactaggat tgatgacttc
    60241 tcaaaatccc ccttataatc taactttaag tagagaatag aattttctag ctgttctatt
    60301 ttctacgtct agtctttctt cctagcaaag caaaaccact tgttgccacc actagaccaa
    60361 gactagcaag tgctgcactt gatgctgaac ctgtgttagg taattgtttg ccagcaggtg
    60421 actggtaggt aacatcttgc attgttcctg cagttgcttg cggtgcactt gttgtcttag
    60481 gagcagcatt aggagccact ggtctcttag gaactgtaac catggcaatg gcttgcactc
    60541 caatcgtttc tgcttccttc acatcttcca tagttttcgc attttcaatc tctttgagag
    60601 ctgcttgttt ttctgcttcc actcttgcta aaagttctgc tttttcttta tcagaaagcg
    60661 gtgcgccttt gatttcatcc tgcttatcct tggctgcttt ttcaatggca tttttagctg
    60721 attctttttc agtagctaat tgcttagaag cttgtgattg agctgagttt tgtgaacctg
    60781 tgtgagctga tccacccgcc tggctaccac cgccttcatt cgcattagca tctgagcttc
    60841 cagtattgcc tcccttatct ccacctggta tagtttctag cttatactct agtgtagctt
    60901 cttgagttac agattcacct ttcgcagatt gttgaactgt atcttttcct agaatcgtca
    60961 ctactgaacc atctgggaat gtgattgttg ctgtaccatc tccagctaca ttgattgtcg
    61021 ctccgtctaa tgctgaacca tttgcttgta aaatagcaac cttaactttt tcttcatctg
    61081 ttaaatgagt tatatctttt acatctactc tttgagcagg tgctttaaca gttgattttt
    61141 cagcagtcgg tttagtgcta tcttgtgctt ttggatcttg tgctaccaat tgatttcctg
    61201 gaattgtaat agctgaacca tctttaaaga cgattgttgc tgtaccatct ccacctactt
    61261 caactttata gtaaaataaa ataataacag gacaaatcga tcaggacagt caaatcgatt
    61321 tctaacaatg ttttagaaac agaggtgtac tattctagtt tcaatctact ataacatcgc
    61381 ttccgaatcc atttgcatct actgaacttt tttacaaaaa taaaaatcag tagactcgag
    61441 ttcctactga tttttgatag aattcgtttg gattatgcag ccaaaacttt gcgtccttta
    61501 cgacgacgag ctgccaatac gcgacgacca tttttagttg acatacggtt acggaatccg
    61561 tgtttacgcg cacgacgaag tttacttggt tgataagtac gtttcacgat gaatacctcc
    61621 tcatagattt tgtattcgtt tagccggcta taaagtgatc agttactaaa catactttac
    61681 tattctatct gattctttca cttttgtcaa tagctctagg caaatgtttc cagctttttc
    61741 gaatgcaagc cct
//
LOCUS       DBERCW010000009        58510 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.009, whole genome shotgun sequence.
ACCESSION   DBERCW010000009 DBERCW010000000
VERSION     DBERCW010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 58510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.009"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(68..1048)
                     /gene="dusB"
                     /locus_tag="ACL72M_000709"
     CDS             complement(68..1048)
                     /gene="dusB"
                     /locus_tag="ACL72M_000709"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGS0715876.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1035..1907)
                     /gene="hslO"
                     /locus_tag="ACL72M_000710"
     CDS             complement(1035..1907)
                     /gene="hslO"
                     /locus_tag="ACL72M_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGS0715877.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2072..3499
                     /locus_tag="ACL72M_000711"
     CDS             2072..3499
                     /locus_tag="ACL72M_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0715878.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            3658..5166
                     /gene="glpK"
                     /locus_tag="ACL72M_000712"
     CDS             3658..5166
                     /gene="glpK"
                     /locus_tag="ACL72M_000712"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGS0715879.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNFVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5208..7034
                     /gene="glpO"
                     /locus_tag="ACL72M_000713"
     CDS             5208..7034
                     /gene="glpO"
                     /locus_tag="ACL72M_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGS0715880.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7104..7808
                     /locus_tag="ACL72M_000714"
     CDS             7104..7808
                     /locus_tag="ACL72M_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS0715881.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8105..8308
                     /locus_tag="ACL72M_000715"
     CDS             8105..8308
                     /locus_tag="ACL72M_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715882.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8395..9003)
                     /locus_tag="ACL72M_000716"
     CDS             complement(8395..9003)
                     /locus_tag="ACL72M_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715883.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            9135..9326
                     /locus_tag="ACL72M_000717"
     CDS             9135..9326
                     /locus_tag="ACL72M_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715884.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNK"
     gene            10137..11414
                     /gene="ltrA"
                     /locus_tag="ACL72M_000718"
     CDS             10137..11414
                     /gene="ltrA"
                     /locus_tag="ACL72M_000718"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGS0715885.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGISTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVVSEAAAKRMMYSVSRFIEKRLGLKANMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            11870..13048
                     /locus_tag="ACL72M_000719"
     CDS             11870..13048
                     /locus_tag="ACL72M_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
                     /protein_id="HGS0715886.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13362..13493
                     /locus_tag="ACL72M_000720"
     CDS             13362..13493
                     /locus_tag="ACL72M_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGS0715887.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13514..15064
                     /gene="dltA"
                     /locus_tag="ACL72M_000721"
     CDS             13514..15064
                     /gene="dltA"
                     /locus_tag="ACL72M_000721"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGS0715888.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNAHIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFENLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15061..16305
                     /gene="dltB"
                     /locus_tag="ACL72M_000722"
     CDS             15061..16305
                     /gene="dltB"
                     /locus_tag="ACL72M_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGS0715889.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16319..16558
                     /gene="dltC"
                     /locus_tag="ACL72M_000723"
     CDS             16319..16558
                     /gene="dltC"
                     /locus_tag="ACL72M_000723"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGS0715890.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16551..17819
                     /gene="dltD"
                     /locus_tag="ACL72M_000724"
     CDS             16551..17819
                     /gene="dltD"
                     /locus_tag="ACL72M_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGS0715891.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLQQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            17974..18414
                     /gene="adcR"
                     /locus_tag="ACL72M_000725"
     CDS             17974..18414
                     /gene="adcR"
                     /locus_tag="ACL72M_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGS0715892.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18414..19118
                     /locus_tag="ACL72M_000726"
     CDS             18414..19118
                     /locus_tag="ACL72M_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS0715893.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19111..19917
                     /locus_tag="ACL72M_000727"
     CDS             19111..19917
                     /locus_tag="ACL72M_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGS0715894.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAVVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            19927..21432
                     /gene="adcA"
                     /locus_tag="ACL72M_000728"
     CDS             19927..21432
                     /gene="adcA"
                     /locus_tag="ACL72M_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGS0715895.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYTEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22603..23376)
                     /locus_tag="ACL72M_000729"
     CDS             complement(22603..23376)
                     /locus_tag="ACL72M_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0715896.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            23552..24955
                     /locus_tag="ACL72M_000730"
     CDS             23552..24955
                     /locus_tag="ACL72M_000730"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGS0715897.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25070..25708
                     /locus_tag="ACL72M_000731"
     CDS             25070..25708
                     /locus_tag="ACL72M_000731"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGS0715898.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            25720..26160
                     /locus_tag="ACL72M_000732"
     CDS             25720..26160
                     /locus_tag="ACL72M_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGS0715899.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26153..26584
                     /locus_tag="ACL72M_000733"
     CDS             26153..26584
                     /locus_tag="ACL72M_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0715900.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26575..27045
                     /locus_tag="ACL72M_000734"
     CDS             26575..27045
                     /locus_tag="ACL72M_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0715901.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27070..27843
                     /locus_tag="ACL72M_000735"
     CDS             27070..27843
                     /locus_tag="ACL72M_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS0715902.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            27840..28640
                     /locus_tag="ACL72M_000736"
     CDS             27840..28640
                     /locus_tag="ACL72M_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0715903.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28699..30993
                     /locus_tag="ACL72M_000737"
     CDS             28699..30993
                     /locus_tag="ACL72M_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS0715904.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELCIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31003..34119
                     /locus_tag="ACL72M_000738"
     CDS             31003..34119
                     /locus_tag="ACL72M_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGS0715905.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34176..35942
                     /locus_tag="ACL72M_000739"
     CDS             34176..35942
                     /locus_tag="ACL72M_000739"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGS0715906.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36088..37239
                     /locus_tag="ACL72M_000740"
     CDS             36088..37239
                     /locus_tag="ACL72M_000740"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGS0715907.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37384..38268
                     /locus_tag="ACL72M_000741"
     CDS             37384..38268
                     /locus_tag="ACL72M_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS0715908.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            38667..38918
                     /locus_tag="ACL72M_000742"
     CDS             38667..38918
                     /locus_tag="ACL72M_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGS0715909.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            38906..39196
                     /locus_tag="ACL72M_000743"
     CDS             38906..39196
                     /locus_tag="ACL72M_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS0715910.1"
                     /translation="MGALGYYEGFVPYVSNQYQNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(39400..39507)
                     /locus_tag="ACL72M_000744"
                     /pseudo
     CDS             complement(39400..39507)
                     /locus_tag="ACL72M_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(39601..40932)
                     /locus_tag="ACL72M_000745"
     CDS             complement(39601..40932)
                     /locus_tag="ACL72M_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGS0715911.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(40954..42465)
                     /locus_tag="ACL72M_000746"
     CDS             complement(40954..42465)
                     /locus_tag="ACL72M_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGS0715912.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(42676..43623)
                     /gene="arcC"
                     /locus_tag="ACL72M_000747"
     CDS             complement(42676..43623)
                     /gene="arcC"
                     /locus_tag="ACL72M_000747"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGS0715913.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(43788..44804)
                     /gene="argF"
                     /locus_tag="ACL72M_000748"
     CDS             complement(43788..44804)
                     /gene="argF"
                     /locus_tag="ACL72M_000748"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGS0715914.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(44862..46091)
                     /gene="arcA"
                     /locus_tag="ACL72M_000749"
     CDS             complement(44862..46091)
                     /gene="arcA"
                     /locus_tag="ACL72M_000749"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGS0715915.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            46847..48526
                     /locus_tag="ACL72M_000750"
     CDS             46847..48526
                     /locus_tag="ACL72M_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004560 - alpha-L-fucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGS0715916.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQQVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLYFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48566..50650)
                     /locus_tag="ACL72M_000751"
     CDS             complement(48566..50650)
                     /locus_tag="ACL72M_000751"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGS0715917.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKILVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            50821..52101
                     /locus_tag="ACL72M_000752"
     CDS             50821..52101
                     /locus_tag="ACL72M_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGS0715918.1"
                     /translation="MIYPKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52192..54837
                     /locus_tag="ACL72M_000753"
     CDS             52192..54837
                     /locus_tag="ACL72M_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGS0715919.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            54921..55790
                     /locus_tag="ACL72M_000754"
     CDS             54921..55790
                     /locus_tag="ACL72M_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS0715920.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLYRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            55784..57664
                     /locus_tag="ACL72M_000755"
     CDS             55784..57664
                     /locus_tag="ACL72M_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGS0715921.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVMGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            58078..58404
                     /locus_tag="ACL72M_000756"
     CDS             58078..58404
                     /locus_tag="ACL72M_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715922.1"
                     /translation="MILWGFDFANDHAHAFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
BASE COUNT        17674 a        10721 c        12868 g        17247 t
ORIGIN      
        1 tttttttgat gaggaaagaa tggcggcact caagagactc tttaagagag ttacgggttt
       61 taaactatta agccttctcc aattgcaaga gagcttcaat ctctgccagg gtgctagctt
      121 gcgaaatggc tccacggagt ttggcagcgc cagatgttcc acggaggtag tgaggagcga
      181 ggccacggaa ttcacgaact gcgacgtttt ctcctttgag gttaatcaat cgtttcaagt
      241 gttcgtaggc gatcttcatc ttgtcttcaa aggtcaaatc aggtaggatt tctcctgttt
      301 caaagtaatg gttgatttgg ttgaagaggt aaggatttcc catggcagct cggccaatca
      361 tgactgcgtc agcaccaact tcttcgatgc gttgcttggc ttcttggaca gtacggatat
      421 caccgttggc gatgaatgga atcttggtta gagcttgggc aaccttgtac agggtctcaa
      481 ggtctgcgtg gccagtatac atttgttcac gggtacggcc atgcatggcg agggcagaaa
      541 cacctgcagc ctcagcagcg agggcatttt ctactgccag agatgggtcc gcccagccgg
      601 tacgcatttt gacagtaagt gggatatcaa ggacagactg gaccttgttg atgatagagt
      661 agatcttgtc aggatccttg agccacatag ctccagcttc gttcttcacg attttgttga
      721 cagggcagcc catgttgata tcgacgatat cggtcttggt gttttcttgg atgaattctg
      781 ctgcgcgtgc taggctgtct tcatcgctac caaaaagttg gatagagaca gggttttcgc
      841 cctcatcgat atgaagcatg tgcagggttt tttcgttgtt gtattggatt cccttgtcag
      901 agaccatttc cattacaacg agtccagctc cgagctcttt tgcgatggta cgaaaggctg
      961 agttggtcac gccagccata ggcgctaaaa cggtacgatt gggaatctca acattgccaa
     1021 tcataaaagg tgtattaaga tttgtcacga atgagttcct ccaggtcctt ttcatcaaag
     1081 ttgtaagtag tttggcagaa ttgacaagtg atttctaccc cgtggtcttc ctctttcatt
     1141 tcctgtaagt ctgagcttgg aaggctggca agagcgttca taaagcgttc atggctacag
     1201 tcacattgga aacggatttc ttcttcagaa agacgcttgt aggcttcgtc cccgtagata
     1261 gccttgagga gggcttcgat atggtcgtcg ctttcgagaa gagtagagat agctggcatt
     1321 tcttggatgc gtttttcaaa gcgagcaatc tcttctttct tggctcctgg caagacttga
     1381 actaggaaac cacctgcaac cttgaccttg tcttcctcgt ccaaaaggac attgaggccg
     1441 accgctgaag gcgtttgttg gctttcagta aggtaaaagg caaggtcttc accgatttct
     1501 ccagagatga ggggagttat agagttgtaa ggatttccag caccgtagtc tgtgataacg
     1561 aggaattgac catttccaac aaaaggtccg actaggactt caccagtcgc agtctttttg
     1621 atgtcaacac caggattttg aacatagcct ttgacgttcc ccttggtatc agcgacggtg
     1681 ataatagcac ctagagagct agagcccaac accttaactg taagtttggt atttcctttt
     1741 tcattggctg cgagaatctg gctggcgata agagttcgac caagcgctac agttgagcta
     1801 gcttgggttt gatgtttttc ttgagcagtg cggacggttt ccgtgctatc aaggacaaaa
     1861 gcacgaaagg ctccgctttc tgatatagtt ttaataattt tatccatagc tactatttta
     1921 gcataaaaat gcccaaaggg ggagccgtgt gtttactgat tttcaggata atggaccagg
     1981 aaatcagcat gaaaataaaa agagaaacag attattttag catttgtaag atttatgcta
     2041 tgcttaaggt agaaaatgaa aggggtaaca aatgtattta ggagatttga tggagaaagc
     2101 cgagtgtggt caattttcaa tcctttcctt tctattacaa gagtctcaga cgaccgtcaa
     2161 ggctgtaatg gaagaaacag gattttcaaa agcaacccta accaaatatg tcaccctgct
     2221 caatgacaag gctttggata gtggcttaga gctggctatt cactcagaag atgaaaatct
     2281 gcgtctgtct atcggtgcag ctaccaaggg gagagatatt cggagcttgt ttttggagag
     2341 tgctgttaaa taccagattt tggtttatct tctctaccac caacagtttt tagcccatca
     2401 gctggctcaa gaattggtga ttagcgaggc tacgcttggt cgtcacttgg ctggtttaaa
     2461 tcagattttg tcagaatttg atttatccat ccaaaatgga cgttggcgag gtccagagca
     2521 tcagattcgc tatttctatt tctgtctttt ccgaaaggtc tggtcgagtc aggaatggga
     2581 aggtcacatg cagaaaccag agagaaaaca ggagattgcc aatttagagg aaatctgcgg
     2641 tgcaagtttg tctgtggggc agaaattgga cttggttctc tgggctcaca tcagtcaaca
     2701 acgtcttcgg gtcaatgctt gtcagtttca agtcatagaa gagaaaatgc gagggtattt
     2761 tgacaatatt ttctaccttc gtttgctgag aaaggttccg tccttttttg ctgggcaaca
     2821 tattccacta ggagttgagg atggtgagat gatgatattc ttctcttttc tcctatctca
     2881 tcgcattctt cctcttcata ctatggagta tattcttggt tttggagggc agttggcaga
     2941 tttactgacg caattgattc aagaaatgaa gaaggaggaa ctattggggg attatacaga
     3001 ggaccatgtc acctatgaac tcagtcagct ttgtgctcaa gtctatctct ataagggcta
     3061 tattttacag gatcgctaca agtaccagtt agagaatcgt catccatatt tactgatgga
     3121 acatgatttt aaagagacag cagaggagat ttttcatgct ctacctgctt ttcaacaggg
     3181 gacagattta gataagaaga ttctctggga atggctccag ttaatcgaat atatggctga
     3241 aaacggtggc cagcatatgc ggattggtct ggatttgaca tctggttttc ttgtcttttc
     3301 aaggatggca gccattttga aacggtattt ggaatacaat cgttttatta ccattgaagc
     3361 ctatgaccct agtcggcatt atgatttgct ggttaccaat aacccgattc ataagaagga
     3421 acagacacca gtctattatt taaaaaatga cttggatatg gaggatttgg tagcgattcg
     3481 ccagttatta ttcacttaaa aggcttggtt aatccaggtc ttttttgtga aattcacaca
     3541 atctcctcac atttttttaa aaattaaaaa aagttgataa acaagaaagc gctttatttt
     3601 gtatactagt aagtgtaaag aggaaacacc tcaagatctt tatcaggagg acagtacatg
     3661 tcacaagaaa aatacatcat ggccattgac cagggaacta caagttctcg tgccatcatt
     3721 ttcaacaaaa aaggggaaaa ggttagctcg agtcaaaaag agtttaccca gattttccct
     3781 caggcaggtt gggttgagca caatgccaat gaaatttgga actttgttca gtcagttatt
     3841 gcgggtgctt tcatcgaaag tggtgtcaag ccaaatcaaa tcgaggcaat cgggattacc
     3901 aaccaacgtg aaacaacggt tgtctgggat aagaaaacag gacttcctat ctacaatgct
     3961 atcgtttggc agtcacgcca gacagcacct ttggctgagc aactaaaaag ccaaggttat
     4021 gtggaaaaat tccatgaaaa gactggtttg attattgatg cttacttctc tgctaccaag
     4081 gttcgttgga ttttggatca tgtagaaggt gctcaagagc gagcagaaaa aggggaattg
     4141 ctctttggta ctatcgatac ttggttggtt tggaaattga ctgacggtgc ggctcacgtg
     4201 actgactact caaatgcagc tcgtaccatg ctttataaca ttaaagaact caaatgggat
     4261 gatgagattt tggaaatcct taacattccg aaggctatac ttccagaagt tcgttctaac
     4321 tccgaaatct acggcaagac agctccattc catttctacg gtggagaggt gccaatctca
     4381 ggtatggctg gggaccaaca agcagccctc tttggacagt tggcttttga gccaggtatg
     4441 gttaagaata cttatggaac aggctctttc atcatcatga atactgggga agagatgcag
     4501 ttgtctgaaa acaacctctt gacaaccatt ggttacggaa tcaacggtaa ggtttattat
     4561 gccttggaag gttctatctt catcgcagga agtgctattc agtggcttcg tgacggtctt
     4621 cgcatggttg aaaattcacc agaatctgaa aaatacgctc gtgattctca caacaacgat
     4681 gaagtttatg tcgttccagc ctttacaggt ctaggcgctc catactggaa ccaaaatgct
     4741 cgtggttccg tctttggttt gactcgtgga acaagcaaag aagactttat caaggcgact
     4801 ttgcaatcta ttgcttatca agtgcgtgat atcatcgaca ccatgcaagt ggatactcag
     4861 accgccattc aagtactgaa ggtggatggt ggtgcagcca tgaacaactt cctcatgcag
     4921 ttccaggcgg atattttagg cattgacatt gcacgtgcta aaaacttgga aacaacagct
     4981 ctaggagcgg ccttcctagc aggtttgtca gtagggtact ggaaagactt ggacgagttg
     5041 aaactcttga acgagacagg agaactcttt gagccatcta tgaacgaatc tcgcaaggaa
     5101 caactctaca agggctggaa gaaggctgtg aaagcaactc aagtctttgc ggaagtagac
     5161 gactaatact ggcagaataa agcgatttat ttagaaagtg tgtaaatatg gaattttcaa
     5221 aaaaaacacg tgaattgtca attaaaaaaa tgcaggaacg caccctggac ctcttgatta
     5281 tcggtggagg aatcacagga gctggtgtag ccttgcaggc ggcagctagc ggtcttgaga
     5341 ctggtttgat tgaaatgcaa gactttgcag aaggaacatc tagtcgttca acaaaattgg
     5401 ttcacggagg tcttcgctac ctcaaacaat tcgacgtaga agtggtctca gatacggttt
     5461 ctgaacgtgc agtggttcaa caaatcgctc cacacattcc aaaaccagat ccaatgctct
     5521 taccagttta cgatgaagat ggagcaacct ttagcctctt ccgtcttaaa gtagccatgg
     5581 acttgtacga cctcttggca ggtgttagca acacaccaac tgcgaacaag gttttgagca
     5641 agaaagaagt cttggaacgc cagccaaact tgaagaagga aggcttggta ggaggtggag
     5701 tgtatcttga cttccgtaac aacgatgcgc gtctcgtgat tgaaaacatc aaacgtgcca
     5761 accaagacgg tgccctcatt gccaaccacg tgaaggcaga aggcttcctc tttgacgaaa
     5821 gtggcaagat tacaggtgtt gtagctcgtg atctcttgac agatcaagta tttgaaatca
     5881 aggcccgtct ggttattaat acaacaggtc cttggagtga taaagtacgt aatttgtcta
     5941 ataagggaac gcaattctca caaatgcgcc caactaaggg agttcacttg gtagtggatt
     6001 caagcaaaat caaggtttca cagccagttt acttcgacac aggtttgggt gacggtcgta
     6061 tggtctttgt tctcccacgt gaaaacaaga cttactttgg tacaactgat acagactaca
     6121 caggtgattt ggagcatcca aaagtaactc aagaagatgt agattatcta cttggcattg
     6181 tcaacaaccg ctttccagaa tccaacatca ccattgatga tatcgaaagc agctgggcag
     6241 gtcttcgtcc attgattgca gggaacagtg cctctgacta taatggtgga aataacggta
     6301 ccatcagtga tgaaagcttt gacaacttga ttgcgactgt tgaatcttat ctctccaaag
     6361 aaaaaacacg tgaagatgtt gagtctgctg tcagcaagct tgaaagtagc acatctgaga
     6421 aatatttgga tccatctgca gtttctcgtg ggtctagctt ggaccgtgat gacaatggtc
     6481 ttttgactct tgctggcggt aaaatcacag actaccgtaa gatggctgaa ggagctatgg
     6541 agcgcgtggt tgacatcctc aaagcagaat ttgaccgtag ctttaaattg atcaattcta
     6601 aaacttaccc tgtttcaggt ggagaattga acccagcaaa tgtggattca gaaatcgaag
     6661 cctttgcgca acttggagta tcacgtggtt tggatagcaa ggaagctcac tatctggcaa
     6721 atctttacgg ttcaaatgca ccgaaggtct ttgcacttgc tcacagcttg gaacaagcgc
     6781 caggactcag cttggcagat accttgtccc ttcactatgc aatgcgcaac gagttggctc
     6841 ttagcccagt tgacttcctt cttcgtcgta ccaaccatat gctctttatg cgtgatagct
     6901 tggatagcat cgttgagcca gttttggatg aaatgggacg attctatgac tggacagaag
     6961 aagaaaaagc aacttaccgt gctgatgtcg aagcagctct cgctaacaac gatttagcag
     7021 aattaaaaaa ttaagaaaaa ataaaagagg tggagggcag cattccttgt cgcccgtccc
     7081 ttctttttaa tggagacaga aagatgatga atgaattatt tggagaattt ctagggactt
     7141 taatcctgat tcttctagga aatggtgttg ttgcaggtgt ggttcttcct aaaaccaaga
     7201 gcaatagctc aggttggatt gtgattacta tgggttgggg gattgcagtt gcggttgcag
     7261 tctttgtatc tggcaagctc agtccagctc atttaaatcc agctgtgaca gttggtgtag
     7321 ctttaaaagg tgacttgcct tgggcttccg ttttgcctta tatcttagcc cagttcgcag
     7381 gggccatgtt gggtcagatt ttggtttggt tgcaattcaa acctcactat gaggcagaag
     7441 aaaatgcagg caatatcctg gcaaccttca gtactggacc agccatcaag gatactgtat
     7501 caaacttgat tagcgaaatc cttggaacct ttgttttggt gttgacaatc tttgctttgg
     7561 gtctttacga ttttcaggca ggtatcggaa cctttgcagt gggaactttg attgtcggta
     7621 tcggtctatc actaggtggg acaacaggtt atgccttgaa cccagctcgt gaccttggac
     7681 ctcgtatcat gcacagcatc ttgccaattc caaacaaggg agacggagac tggtcttacg
     7741 cttggattcc tgttgtaggc cctgttatcg gagcagcctt ggcagtgctt gtattctcac
     7801 ttttctagtt tatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta
     7861 ctcaagtaca gcttgcggct agcttcctag tttgctcttt gattttcatt gagtattaga
     7921 aaacaattat gttgatagag cttgggcaag agcccaattt cagcaaaaaa tgaagtaaat
     7981 cttctcataa taaaacgcat catatcaagc acgaaaattc cacgaggtca actacagtca
     8041 gaaagctgaa caacaagcca aaacgcccaa aaaaggcggc aaaaagcaag cacctgcaag
     8101 caacgtgccg aaatggtcaa atcctgatta tgtcaacgaa ttagacccaa aaatcgttga
     8161 tatgctagta gaatttcaca agtcacaagg cactttggaa actcccgagg cgcaagcaga
     8221 aatcgcccaa aaacgtgaag aaatcgagca aaggagagct gagcttgagg ataaaaaaca
     8281 agagcttttg aaccgcttga acaaatagag tttcgcaagt attatgctta caaattactt
     8341 gagcaattaa ctaaaatata aaccctgcct agatataaag gcagggttta tattttagaa
     8401 attcacgtag gttgttacgg tttttacata cccagtatag tttgagtttc tatagtattc
     8461 agtgataaac ttccattttc tttgagcaac atggatataa gtacttgtta tgtagtatgg
     8521 atatgggctt tgtgaatcca agtaagactg ataagcttgt ataccaaaat atgctccacc
     8581 aattattgca ccccatggac cccccaataa agcacctatc ctaccaatca tataactgat
     8641 tccagcacca gtcatgaagt tagcgaatgt gttagcttgt ttattcccat gtattgtgtt
     8701 gacgtaattc caaacattag gatcgtatga tctaaaagat atatttaggt cgatttcatt
     8761 cttttgataa gccatataaa atgccccatt gatatagacg ccgtcagcac gtcgttcaat
     8821 agtgtctaca cttccatctg gattgacaac ctcaagaact tcatcgctta aaatatttac
     8881 ttgcgtatct ccgaaccgca ctgatgagcc attctcaaac tgagcctcac cagatacaac
     8941 tttagagttt gccgataagc tatcatcagc aaaaacaaca agcgacgggg aaatgctaga
     9001 catacagaaa acagacataa ctagcaaaca catgcattta aacatcttag acataacgga
     9061 aactcttttg tatttttgat ttttttcaac ttttattata caataaaacc aaataaaaag
     9121 aaagcggtaa caatatgctt aatgcgaaaa ttttttatat atttttatgt ttgatcgtta
     9181 tcgaaactac aggcttgttg ttgttgaaaa gaggtctcga aatgggttat ttagacacag
     9241 aagctattat cctcgcagtt ttttcatttg ctttttacaa cctatgttca ttcgcttggg
     9301 tctgctctac aataaaaaat aaatagacgt attttcaaaa aaaaaaaaat gaatatttat
     9361 attagcaaaa tgacgattta aatcgtcgtt tttttgtagt acgacgggca tgtcgtatat
     9421 ctgaggtgta agtcctcggt gggcacctgc taccggtgaa cccaatagcg attcccaagc
     9481 ctgactatcg tgaggtagcg gattaaaacg gtctggggat agaccgtttt aagtctgacg
     9541 caggaaataa gaatcgtcag aggaagggat agcgaaatcg tggctctacg aacaggaacg
     9601 tgatagtaag gcgtatatag cggataagga ggcttcaaac tctaaagtcc aaaaaggtag
     9661 tcgtaaccta tatgtgtaaa tcacgagagt aattgaattc ggactaaggt ttgtgtgaaa
     9721 aagataaatc tttctagagt ctaaagactc tgcgtcagat ttcctatttt cactgtaacc
     9781 ttttaacgtc ctcatatctt gtataaacga ggaaagatgt acgacttatc ccgtgaggtt
     9841 tcatgagcgc tgaaagcgta gtaacaacga atcatgagaa gtcagccgag cccatagtag
     9901 tgaggaaact tctgtagtgg aagtggagcg aaggggtgaa tactcaaaca gtctggggag
     9961 agactgtttg aggtctgtcg ctagaaagag aaaacgacag atcgaagtaa tcctacttca
    10021 cttgtgtctg taaaatgagt ggtctgatag aactggactt tgacacgtaa tgactagatg
    10081 aaggttcacc aatataagat gtccctcagg caccaaaaca agaaaggaat acgcacatgt
    10141 caaaactgct agataagata ttatcacgcg aaaatatgct ggaagcctac aatcaagtaa
    10201 aatccaataa aggctcagct gggattgatg gaatgactat cgaagagatg gataattatc
    10261 tcagacaaaa ctggcgcttg actaaggaac tgataaaaca gagaaaatat aagcctcaac
    10321 cagttcttaa agttgagata cctaaaccag acggaggcat ccgtcaacta ggaatctcaa
    10381 cagttatgga tagaatgatt caacaggcca ttgtccaagt catgagcccc atttgtgaac
    10441 cccatttctc agatacgagt tatggtttca gaccaaatag gtcatgtgaa aaagccatca
    10501 tgaagctctt agaatactta aatgacggct atgagtggat agtggatata gacctagaga
    10561 aatttttcga tacagttcct caagatagat tgatgtcctt agtacataac attatcgaag
    10621 acggagatac ggaatccttg attcgtaagt atcttcattc aggtgttatc attaatggtc
    10681 aacgttataa aacactagtt ggtacaccac agggaggaaa tttatctcct ctcttatcca
    10741 atatcatgct taatgaattg gacaaggaat tagaaaagag gggacttcga tttgtgcgct
    10801 acgcagatga ttgtgtgatt acggtcgtaa gcgaggcagc cgctaagcgt atgatgtatt
    10861 cagtcagtcg ttttattgaa aaacggctag gtttgaaagc aaacatgacc aagactaaga
    10921 ttaccagacc aagagagttg aaatatctag gttttgggtt ctggaaatca tcagatggtt
    10981 ggaaaagtcg tccacatcaa gatagtgttc ggagatttaa gcttaaattg aagaaactaa
    11041 cacagaggaa atggagtata gacctaacaa gacgtattga gcaactgaat ttgtctattc
    11101 gaggatggat aaactatttc tcattgggaa atatgaaaag tatagtcgcc agcatagatg
    11161 agcgcttgcg tactcgccta cgagtgatta tctggaagca atggaagaag aaatcgagac
    11221 gattatgggg attgcttaag ttaggggttc ctaaatggat agcagataag gtatctggct
    11281 ggggcgacca ttatcaatta gtagctcaga agtcggtact taaacgtgct atatcaaaac
    11341 cagtcctgga aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa cgacatgcgt
    11401 taaaagttag ttgaaccgct gtatgccgaa cggcacgtac ggtggtgtga gaggggctag
    11461 agattatccc ctactcgatt aactcccctg aaatttattt taattatgca aatttcacgt
    11521 atttttgatg ctgagacgac gatcctggga acttttcaga tatttttttg actatctaaa
    11581 tctatcatta gaaaagctta gagcgccaaa ggatttgagc gtttttctga tttttaagac
    11641 tttttccagt ctctttttcg attgaagatg taattattct actaactaac taacttctta
    11701 gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata aaggcaatag
    11761 tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat gctaaaatat
    11821 taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca tgtctaattc
    11881 atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt tctttagagt
    11941 aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat cactagttcc
    12001 tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg ttactaaaag
    12061 gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat tattggcgat
    12121 actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct atctatttgt
    12181 tgttgcaatt tccatactag atggttttgc agcacctgtt tcctatgcta ttgtgccacg
    12241 ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg aagctgttca
    12301 attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt tacctaccac
    12361 gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc ttcctaacgc
    12421 tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag gttggaagtt
    12481 agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg aaattttttc
    12541 aaatacgatt tgggtttctt ccattatact tgtttttgta acggagttat taaataaaac
    12601 ggaaagttac tggggatatt ctaatacagc atactctatt ggtattataa ttagtggctt
    12661 aattgctttt aggctatctg aaaagttcct tgctgctaaa tgggaaagta ttctttttcc
    12721 tcttgtagct atggcaatag tgacactgac tattctatat tttccaaacg cacagatgtt
    12781 tttattattt tcagctttag ttggtatgtt atcgcaacta aaagaagttc ctgaaagtgt
    12841 atttcttcag gaaacagtag aggaaaatca tttagttaat gtctattccg ttcttgaagt
    12901 gatttctaca ttagcatttt cagtatttgt tttgctaatg agctatatta ctgagagttt
    12961 tggtattagc atcagttttt ggctatcagc catttgtctg atgatagaag ctattttaat
    13021 ttatatcaga cgagattatt ttaaatgaga gagtggttaa aaagtcttta aaaatcagaa
    13081 aagcgcatag tatcaggtgt tgaaaaaact tgatattgtg tgttttatta tgggaagatt
    13141 tacttcattg tctcctgaaa tggagttttg aagcaggatc actctatttg aaaatataca
    13201 tagaaaaact gtataatcct taaaataagc tgaaatctat tggaaacata cggtaaacaa
    13261 ttgaaaagat actatataaa gtggtacaat ggtagaaaaa taagctagta agaatcactc
    13321 ttattttagc gaaaaattac agaaatgaat ggtttttctt gatgaaacag agaaaagaat
    13381 tgtacctctt tcttggtcgg acagccttgt attttcttat ctttctaggg ctgctttact
    13441 tctttagcta tcttggtcag ggtcaaggaa gctttatcta taatgaattt taacttgaag
    13501 gagaatccct attgtgtcaa ataaaccaat agcagatatg attgaaacca ttgagcattt
    13561 tgctcagaca cagcctagct atcctgtcta taatgttttg gggcaggaac acacttatgg
    13621 cgatttaaag gctgattcgg atagtttggc tgcagtcatt gaccaactag gcttgcctga
    13681 gaagtctcct gtggttgttt ttggtggcca agaatatgaa atgttggcaa cctttgtagc
    13741 gctgactaag tcaggtcatg cctacattcc aattgatagc cattcggcct tggagcgagt
    13801 ttcagctatt ttagaagtag cagagccaag cttgattatt gccatttcag cctttccctt
    13861 ggagcaggtt tctacaccaa tgataaatct agctcaggtt caagaagcct ttgcccaagg
    13921 gaataactat gaaatcacgc atccagtcaa gggagatgat aattactaca ttatctttac
    13981 ttctggtacg actggtaagc ctaagggagt gcagatttca catgataatc tcctcagctt
    14041 tacaaactgg atgattacgg ataaggaatt tgcgacaccg agtcgtccgc aaatgctggc
    14101 acagccacct tattcttttg acttgtctgt catgtattgg gcaccgacct tggcacttgg
    14161 tggtacgctt ttcactcttc cttcagtcat cactcaggac tttaagcaac tctttgcggc
    14221 tatcttttca ttgccaatcg ctatctggac atcaacacca tcctttgcag atatggccat
    14281 gttgtctgaa tacttcaaca gtgagaaaat gcctggaatc actcatttct actttgatgg
    14341 tgaagaattg acggtcaaaa cagctcaaaa actgcgcgag cgtttcccaa atgcccatat
    14401 catcaatgct tacggcccaa cagaagcgac agtagctctg tcagcagttg ccgtgacaga
    14461 cgagatgtta gcgactctca aacgcctacc aatcggctat accaaggctg attctccaac
    14521 ctttatcatt gacgaggaag gaaataaact gccaaatggt gagcagggag aaatcattgt
    14581 ttctgggcca gctgtttcaa aaggttatat gaacaatcct gaaaaaacag cagaagcctt
    14641 ctttgagttt gaaaatctgc cagcctatca cacaggcgat gtgggaacca tgacagatga
    14701 gggcttgctt ctctacggcg gacgcatgga cttccagatt aagttcaacg gttaccgcat
    14761 tgagttagaa gatgtctctc aaaacctcaa caagtctcgc tttatcgaat ctgctgtcgc
    14821 agtaccgcgc tataacaagg accacaaggt acaaaatcta ttggcttatg tcatcttaaa
    14881 agacggtgtt cgtgagcagt ttgagcgaga tatcgatatt accaaggcca tcaaggaaga
    14941 cctgacagac atcatgatgt cctacatgat gccatctaaa ttcctttacc gagacagttt
    15001 gccactaact ccaaatggaa agattgacat caaaggattg attaacgagg tgaataagag
    15061 atgatggagt tttttcaaca gcttcctcat ttagagccat atggtaatcc tcagtatttt
    15121 gtttatgtga ttgctgcaac cttgcccatc tttataggcc tctttttcaa gaaacgcttt
    15181 gcctggtatg aagtgttggt aagtctcttc tttattgtca ccatgttggt gggtggaaag
    15241 accaatcaac tagctgcctt gggtatttac ctttgctggg aaatattgct cctgcttttc
    15301 tacaagcatt atcgaaaaag caaggatggc aagtgggtct tctacttagt tagttttctg
    15361 tccctacttc cgattatctt tgtcaaggtg caaccagcta tcaatggaac gcagtctttg
    15421 cttgggttct tgggaatttc ttacctgacc tttcgttcgg ttgggattat catcgagctg
    15481 agagatggag tgattaagga ttttaccctc tgggaattcc tccgtttcct tctcttcatg
    15541 ccaactttct cgagtggtcc aatcgatcgc tttaagcgat ttaatgaaaa ttatcagacc
    15601 attcctgagc gagatgagtt gatggatatg ctggatgaat ctgtccgcta tatcatgcgg
    15661 ggctttttgt ataagtttat cctagctcat gttttaggag agaccttact acctcctctg
    15721 aagaatttag ccttgcagtc aggtggcttc tttaatctct atgccttggc agttatgtat
    15781 acttttggtc tggagctctt ctttgacttt gcaggttatt ctatgtttgc tttggccatc
    15841 tcaaacttga tgggaatccg tagccctatc aactttaaca agcccttttt atcaagggat
    15901 ttaaaggagt tttggaatcg ctggcatatg agtctgtcct tctggttccg tgactttgtc
    15961 tttatgcgaa tggtgatggt gttaaccaga aagaaagtct ttaaaaatcg taatgtaacc
    16021 tcaagcatgg cctacattgt aaatatgctg attatgggat tttggcatgg cgtgacctgg
    16081 tactatatcg cctatggact ctttcatgga ctaggtttgg tcatcaatga tgcctgggtt
    16141 cgcaagaaaa aaacgctcaa taaggaacgg aaaaaagcag ggaaggctgc cctacctgag
    16201 aatcgctgga ttcagttgct tggcatggtt gtcactttcc atgttgtcat gttgtcattc
    16261 ttaatctttt ctggattctt gaataatcta tggtttaaaa aataaaagga aataaaatat
    16321 ggatatcaaa tcagaagtta tcgaaattat tgatgagttg tttatggaag atgtttctga
    16381 catgatggat gaagatcttt ttgatgcagg tgtcttggat agtatgggaa cggttgagtt
    16441 gattgtggag attgagaacc gttttgacat tcgtgtccct gtaacagagt ttggtcgtga
    16501 cgactggaat acagctaata aaattatagc tggtattgtg gagctacaaa atgcttaaac
    16561 gcttatggat gatcttcgga ccggtcttga tcgctggttt gttggttttt ctgctcattt
    16621 tcttttatcc tactgagatg catcataatc taggagctga aaagcgttca gcagtggcta
    16681 ctactatcga tagttttaag gagcgaagtc aaaaagtcag agcactatct gatccaaatg
    16741 tgcgttttgt tcccttcttt ggctctagtg aatggcttcg ttttgacggt gctcatcctg
    16801 cggtattagc tgagaaatac aatcgttcct accgtcctta tcttttagga caggggggag
    16861 ctgcatcgct taaccaatat tttggaatgc aacagatgtt acaacagctg gagaataaac
    16921 aagttgtgta tgttatctca cctcagtggt tcagtaaaaa tggctatgat ccagcagcct
    16981 tccagcagta ttttaatgga gaccagttga ctagttttct gaaacatcaa tctggggatc
    17041 aggctagtca atatgcagcg actcgcttac tgcaacagtt cccaaacgta gctatgaagg
    17101 acctggttca gaagttggca agtaaagaag aattgtcgac agcagacaat gaaatgattg
    17161 aattattggc tcgttttaat gaacgccagg cctccttttt tggtcagttt tcggttagag
    17221 gctatgttaa ctacgataag catgtagcta agtatttaaa aatcttgcca gaccagtttt
    17281 cttatcaagc aatagaagat gttgtcaaag cagatgctga aaaaaatact tccaataatg
    17341 agatgggaat ggaaaattat ttctataatg agcagatcaa gaaggatttg aagaaattaa
    17401 aggattctca gaaaagcttt acctatctca agtcgccaga gtataatgac ttgcagttgg
    17461 ttttaacaca gttttctaaa tctaaggtaa acccgatttt tatcattcca cctgttaata
    17521 aaaaatggat ggactatgct ggtctacgag aggatatgta ccaacaaacg gtgcagaaga
    17581 ttcgctacca gttagaaagt caaggtttta ccaatatagc agatttttct aaggacggcg
    17641 gggagccttt ctttatgaag gacaccattc accttggttg gttgggttgg ttggcttttg
    17701 acaaggcagt tgatcctttc ctatccaatc ccacaccagc tccgacttac catctgaatg
    17761 agcgcttttt cagcaaagat tgggcgactt atgatggaga tgtcaaagaa tttcaataga
    17821 taatataata tagaagagtt caagaatgaa actagttttc acgttttttc ttgactcttt
    17881 ttttgcttgt gatataatta actggtaaac aaaatgtcaa agaatagtat ttttctctta
    17941 aaaaagagaa gtctaaaagg aaaggagtca gatatgagac agctagcaaa ggatatcaat
    18001 gcttttttga atgaggtgat tttgcaggcg gaaaatcagc atgaaatcct aataggtcat
    18061 tgcactagcg aggtggccct gaccaatact caggagcata tccttatgct cttgtcagag
    18121 gaatctttaa caaattcaga attggctcgt cgtctcaatg tcagtcaggc ggcagttacc
    18181 aaggccatta agtctttggt caaggaaggg atgttggaaa catctaaaga ttctaaagat
    18241 gcgcgtgtga ttttttatca gttgactgac ttggctcgtc caatcgctga ggagcaccac
    18301 catcaccatg agcatacact tttaacctat gaacaagtgg cgactcagtt tactccaaat
    18361 gaacaaaaag tgattcagcg gtttttgact gctttagtag gagaaatcaa ataatgagat
    18421 atattacggt agaggatttg tccttctatt atgataagga gcctgttctt gaacatatca
    18481 attattgtgt tgatagtggg gaatttgtta ccttgactgg ggaaaatgga gcggctaaga
    18541 cgacgctcat caaggctagt cttggaattc tgcaaccacg cattggaaag gtggctattt
    18601 caaagacaaa tacgcaaggt aagaaattga gaatagccta tcttcctcaa caaattgcca
    18661 gttttaatgc tggttttcca agtacggtct atgaatttgt caagtcgggt cgctatccga
    18721 gaaaaggctg gttccgtcgt ttgaatgctc atgatgagga gcatatcaag gctagtctgg
    18781 actcagttgg catgtgggaa catcgagaca aacgcttggg gtctctatct gggggacaaa
    18841 agcagcgagc ggtaattgcg cgtatgtttg cttctgaccc tgatgtgttt atcctagacg
    18901 agccgacaac ggggatggat gcaggaagta aaaatgaatt ttacgaactc atgcaccaca
    18961 gcgcccatca tcatggcaag gctgttttga tgattaccca tgaccctgaa gaagttaagg
    19021 attatgcgga tcgcaatatt catctagtcc gtaaccaaga ctcgccatgg cgttgtttca
    19081 atgttcatga gaatggccag gaggtgggcc atgcttagtt tattatctta cgactttata
    19141 cagcgcgcct ttttggcggt tattgctatg agtcttttct caccggtatt gggaaccttc
    19201 ctcatcttgc gtcgtcagag tttgatgagt gataccctta gccacgtctc actttcaggt
    19261 gtagcctttg gtctggtttt ggggatttct ccaactgttt ctactattgc cattgtcttg
    19321 attgcggcgg tctttctgga gtatctccgt acggtttaca agagctttat ggaaatcggg
    19381 acagctatcc tcatgtcaac aggtctggct gtttctctga ttgtcatgag caagggtaaa
    19441 agctcgagtt caatgagttt ggaccaatat ctctttggtt cgatcgtgac tatcagtgaa
    19501 gaacaggtca tttccctctt tgtcattgcg gtggttgttt tgattttgac ctttctcttt
    19561 cttcgtccta tgtatatctt aacttttgac gaagatacgg cctttgtgga tggcttgcca
    19621 gttcgtacca tgtccattct ttttaacatg gtgacagggg tggctattgc ccttatgatt
    19681 cctgcagcag gagctcttct ggtatcgacc attatggtct tgccagctag tattgccctg
    19741 cgtctgggga aaaactttaa atcggttatg ctgcttgcca gtgcgattgg ctttttggga
    19801 atggtagcag gactttacat ttcctactat gcagaaacac ctgcaagtgc aagtattacc
    19861 attatttttg taactgtctt tatactaatc agtttagtaa gacgttttat caaataggag
    19921 acgaacgtga aaaaaattag cttattacta gccagtctat gtgccttgtt tttagtggct
    19981 tgttccaatc aaaaacaggc agatggtaaa ctcaatatcg tgacaacctt ttaccctgtc
    20041 tatgaattta ccaagcaagt cgcaggagat acggctaatg tagaactcct aatcggtgct
    20101 gggacagaac ctcatgaata cgaaccatct gccaaggcag ttgccaaaat ccaagatgca
    20161 gataccttcg tttatgaaaa tgaaaacatg gaaacatggg tacctaaatt gctagatacc
    20221 ttggataaga aaaaagtgaa aaccatcaag gcgacaggcg atatgttgct cttgccaggt
    20281 ggcgaggaag aagagggaga ccatgaccat ggagaagaag gtcatcacca tgagtttgac
    20341 ccccatgttt ggttatcacc agttcgtgcc attaaactag tagagcacat ccgcgacagc
    20401 ttgtcagcag attatcctga taaaaaagag acctttgaga agaatgcagc tgcctatatc
    20461 gaaaaattgc aagccttgga taaggcttac acagaaggct tgtctcaagc aaaacaaaag
    20521 agctttgtga ctcaacacgc agcctttaac tatcttgcct tggactatgg actcaaacaa
    20581 gtcgcaatct caggcctttc tccagatgca gagccatcag ctgctcgctt ggcagaattg
    20641 acagagtatg tcaagaaaaa taaaatcgcc tatatctatt ttgaagaaaa tgcctcacaa
    20701 gcccttgcta acacactttc aaaagaagca ggtgtcaaaa ctgatgtcct caatccttta
    20761 gaaagtctga cagaagagga caccaaggct ggagaaaact acatttccgt gatggagaaa
    20821 aacctcaagg ctttgaaaca aacaacagac caagaaggcc cagcaatcga acctgaaaag
    20881 gcagaggata ccaagacagt ccaaaatggt tacttcgagg atgcagctgt caaggaccgc
    20941 accttgagtg actatgcagg taactggcaa tcagtttatc ctttccttga agacggcacg
    21001 tttgaccaag tctttgacta caaggctaag ttgactggta agatgaccca ggctgagtac
    21061 aaggcttact atacaaaagg ctatcagaca gatgtgacta agattaacat tactgataat
    21121 actatggaat ttgttcaagg tggacaaagc aagaaataca cttacaagta tgtcggtaag
    21181 aaaattttga cttacaagaa aggcaatcgt ggcgtgcgtt tcctctttga agccacagat
    21241 gctgacgctg gacaattcaa atatgttcag tttagtgacc acaatgttgc cccagttaag
    21301 gcagaacatt tccatatctt ttttggaggt acaagccaag aagctctatt tgaagaaatg
    21361 gataattggc caacctacta cccagataac ctatctggcc aagaaatcgc ccaagaaatg
    21421 ttggcgcatt gatgagaaat cgactagttc ataagagcta gtcggttttt tgatactaga
    21481 tggctaactt cattatagac ctttcagaac taagggaacc tgaaaaaata aataaaactc
    21541 ttgaaatatc tggacttata tgctagaatg tagttagtgt ataaggttca ttagaacacc
    21601 aaagccccta actagtgcca tagttaaggg cttttttgac gtatcttagc gatttaatgg
    21661 gtgtttatag gctagtcagt cggtctactt cttaccatct agccatttgc agacgaaata
    21721 caagataatt ccagctataa catctgctat aatagtaaga gcaagctctg gtataaggct
    21781 cattagtttc acctcctctc acgaacccat aggaacgtaa tcggtaaccg atgacaaaag
    21841 tattatatca cactaaattt agatcatcaa cctcacttaa tgcttgaact attgtagatt
    21901 atatgctaaa atgtagttaa ttgataaggt tcattagaac accaaagccc ctaactatgg
    21961 ccgtagttaa gggctttttt gacgtatctt agcgatttaa cgggtgttta taggctagtc
    22021 actcggtcta cttcttacta tctagccatc tgcagacgaa atacaagata attccagcta
    22081 taacatccgc tataatagta agagcgagct ctatgataag gctcattagt ttcacctcct
    22141 ctcacgaacc cataggaacg taatcggtaa ccgatgacaa aaatagtata ccacaataca
    22201 tttagatcat caaggtcact taattcttga aatatagggt ttaggcgaca aagtctttaa
    22261 aatcagaaaa acgcataata tcaggtgtgc aaaaacttga tactatgcgt tttattgtgg
    22321 gaaggtttac tccattttct cctgaaattg agtttttgtc cagcctctgt ttttagggtt
    22381 gctgagaaaa taatgtcatg tggtgaatat ttgtaaatca gtcagcagac agaacgaata
    22441 ctcttcgaaa atctcttcac atcatgtcag cttcgtcttt ccgtatatat gtgactgact
    22501 tcatcagttc tatctacaac ctcaaaacag tgtttcgagc tgactttatc agttttcaaa
    22561 tctgtacttt gagcaagctg agactagctt cctatttgat tttcattgaa tatcagaaac
    22621 ccattctcca tcaaataatt cgactgcgtc taataatttt tgatctggca cggtgtctga
    22681 aataaaggtt gtgtatttgg agaggggatt aattttaaaa aatccagtct tgtaaaattt
    22741 agaactatca atcagtaaga tggtttcatg ggctttgtca ataatattct tttttgaaat
    22801 agcttggctg agagaagctt cataaacata ttggtcatca atacctcttg ctgaacaaaa
    22861 tgctaaatcg atattaaaat gatctaataa agaattttcc ttatcatagt tgaccacgga
    22921 acaggattga tgtttgacct cgccagatgt gataaagatt ttggagctat ctttaacagt
    22981 ttcagatagg gtttgtgcag tatgtaaacc atttgtaaaa ataatcaaat tatcaagttc
    23041 agaaagatag ggacaaagtt cgtagacagt agtactggaa tccagataaa cacacatacc
    23101 agaccgaata aagtctttag cgagactagc gattagtctt ttttgcctag tactttctcc
    23161 ttcccgtatt tgatgagaaa gttcaattgt gttcatagag gacagggtca cgtatccgtg
    23221 ctttcttttg ataagacctt gattttctaa gaaaattaaa tcacgacgta aggtacttgt
    23281 gctggagaaa gtgatttctg ccagctcttt tacggcaatt ctttttttct ttttaataat
    23341 ttcaatcaat tcaagtacac gttcatcttt tatcataagc tcctcctaat ttatcatttc
    23401 aactatatta tagcacaaat tggaggaatt tgaattattt ttatgaatat tgggttaaca
    23461 tttgaacatt attcaagtaa gcgttcacat attgaaaaaa taaaatgtgg ggattataat
    23521 aaagttaatc aaggacgaag agagaagaaa aatggaagcg gttttagcaa tagatttagg
    23581 tgcgacttct ggaagagcaa tcgttggtta cctttctgaa aataaactag taatggaaga
    23641 aataaatcgc ttttctaatc tacctattag agtaaaaggg catttatctt gggatattga
    23701 ctttctacta gctaaaattc ttgaaagtat ccgcttggct aatactagtt acaagatttt
    23761 atctatcggt attgacacat ggggagttga ttttggactg attgataatg aaggtaagct
    23821 gttatcacaa cctgttcatt atcgtgatga aagaacaaag ggagtgttaa aggaaatatc
    23881 tgaaatgact gaattagaaa aactgtattc agagacagga aatcagatta tggagataaa
    23941 taccttgttt caactcttta aggcacgtca agaatctcct gactctttct ataagaccaa
    24001 taagattctt ttaatgccag atttgtttaa ttatctcttg acaggtaagt ttgctacaga
    24061 aaaaagcatt gcttcaacaa ctcaattatt tgatcctagg agtcaaaatt ggaatcagaa
    24121 tatcttaaaa ctatttgaat tggattcatc tttacttcct gaaattgttt cagagggaaa
    24181 tgttcttgga aggataaaaa aggagtatgg tttaggcgat attcctgttg tgaatgtttg
    24241 tagtcatgat acagcaagtg cgattgtctc agtacctaag acagaaggta gtttatttat
    24301 ttcatcaggt acttggtctt tggttggagt ggaacttact tcaccgattc ttactaccga
    24361 atccttcagt tatggattta caaatgaagt cggtaaagat ggagagatta catttctgaa
    24421 gaattgtaca gggttgtgga tcatagagga actaagacgt tcatttgaac gaagagggaa
    24481 agcctattct tttgatgata ttaggacaat ggtggagaaa gaaaaagaaa atcttcctct
    24541 gattgatact gaatcaactg aatttgcaac agaatctgat atgcacaaga ctttgacaga
    24601 atatctagct tatcatcatg aaactagaga gtggacagat ggacaactat ttaagattgt
    24661 ttatgaaagc ctagctgaaa cgtataggaa agcgatagag ttactagaag aactaactca
    24721 taaggtttat aagaggatat atgtgattgg aggaggtgct agagccagtt actttaacca
    24781 aatgattgct gatagaactg gtaaagaggt tcttacaggt tcgactgagg gtacagctgt
    24841 ggggaatatt gttgtgcagc tcatagctat gggacaatta aaagggatgg aagaagctca
    24901 ccatgttatt gaggagtttc tacaattaga gagttattac tcccaaaaga attaaaaaga
    24961 ttgagagttt gtaaatttgc ctccctcccc cttcttaagt tttgtacaag aaggggggat
    25021 aattggtgaa ttgaaaaata tttagtgttt tgatatgagg aggacaagaa tgtcagatgt
    25081 aaaacaagaa ttaattaagt atggcaagaa gctagtagaa acagatttga cgaaaggaac
    25141 aggtgggaat ctcagtgttt tcgatcgtga aaaacaattg atggcaatta ccccgtcggg
    25201 tattgatttc tttgaaatca aagaatccga tattgtagtg atggatatta atggaaatgt
    25261 tgtagaggga gaacgcttgc catctagcga atggtatatg catttgattc aatatcaaac
    25321 tcgtgatgat atcgatgcaa ttatccatgc tcatacaact tatgcaacag tattagcttg
    25381 tctcagagaa ccacttccgg ctagtcatta tatgattgca gtggcaggga aagatgttcg
    25441 ggtagctgag tatgcaacat atggtacgaa agaattggct gtgaatgcag ctaaagcaat
    25501 ggaaggtcgt agagcagttt tactagcgaa tcatggaatt ttagcaggtg cacaaaattt
    25561 attgaatgca tttaatattg ttgaagaagt tgaatattgt gcaaaaattt attgtttagc
    25621 taagaatttt ggagagccag tagttcttcc tgatgaggag atggatttaa tggcagaaaa
    25681 atttaaaaca tacggtcaga gaaaataggg aggatattaa tgttaaaaca tataccgaaa
    25741 aatatttctc cagatttatt gaagacttta atggaaatgg gacatggaga tgaaatagta
    25801 ttagctgacg cgaattatcc ttctgcctca tgtgcaaata agctaattcg ttgtgatggc
    25861 gtaaatattc cagaattatt agattccatt ctgtatttaa tgccattaga tagttacgtc
    25921 gatagttcaa ttcagtttat gaacgttgtt tcgggtgatg atattcctaa gatatggggt
    25981 acctatagac agatgattga aggtcatggt acagatctta aaacgattac ttatcttaga
    26041 agagaagact tttatgaacg tagtaagaaa gcttatgcta ttgttgctac aggagaaact
    26101 tcactttatg ctaatattat ccttaagaaa ggagtagttg ttgaaagaga aaatgtttaa
    26161 tagaggaatt ttagttgcca gtcatggtaa ttttgctagc ggagctctca tgaccgcaga
    26221 aatgtttgtt ggtgagacaa caaatgatag agttaggaca ttaggtttga tgcctggaga
    26281 gaatattgta gagtttgaac attattttaa aaatcaagta aatgaactgt tagactcaaa
    26341 tcaagaggtt atcgttttga ctgacttgat tggaggaagt cctaataatg tggctttgtc
    26401 acggttttta aatttggatt cagttgatat tgtaacaggg tttaatatcc ctctcctagt
    26461 ggaattaata tcaagttatg attcaaaaat caatttagaa gaaattgttc aaaatgctca
    26521 aaatagtttg tttaatgtta aacaacaact taacgtagag gaggaagagg atttatgtct
    26581 atagagtttg ttcgtattga tgaccgtctg gtacatggtc aagttgtcac tacgtggcta
    26641 aaaaagtatg atattgagca agttatcatt gttaatgatc gcatctcaga agataaaaca
    26701 cgacaatcta ttttaaagat ttctgcaccg gtaggtttaa aaattgtttt ctttagtgta
    26761 aaacggtttg tggaagtttt aaactctgtg ccaataaaaa agagaacaat gctgatatat
    26821 acaaatccaa aagatgtgta tgattctatt gaaggaaatt taaaattgga gtacctcaat
    26881 gtaggacaga tgagtaaaac ggaggaaaat gaaaaggtaa cgggaggtgt agctctaggt
    26941 gaagaagaca aatattattt taagaaaata gttgataagg gaacgagagt tgaaattcaa
    27001 atggttccta atgataaagt tacaatgttg gaaaaatttt tataaaaata atttaaggag
    27061 gtacagtata tgctattcac acaagcatta ctggtgacat tagttgggat tattgccact
    27121 attgactata atggaccgtt atttatgatt caccgtccgt tagttacaag tgcaatggtt
    27181 ggcttagtct taggagattt cacccaaggt gttcttattg gttcagctct tgaattaact
    27241 tggctcggtg taacaggtat tggaggttac actccaccag atactatttc aggtgcgatt
    27301 attggtactg catttggtat tttgtctggt caaggagaaa ctgctggtat cgctatagca
    27361 gttccaattg cagttgctac tcaacagttg gatgttcttg caaaaacttt agatgtttat
    27421 tttgtgaaaa aagctgataa tgatgctaaa aacggagatt attcaaagat cggtttttat
    27481 cattattcaa gtttggtttt aatcacttta tttaaaattg taccaatttt cctagctatt
    27541 atgcttggag gggaatatgt ggcagacttg tttgctaagg ttccaccaat cgttatgcag
    27601 ggacttaact ctgcaggtgc tttactacct tcaattggtt ttggtatgct tttaaatatg
    27661 atgctcaaga aaaatatgtg ggtattcttg ttgattggat tcatttgttc tgtgtatgga
    27721 ggaatgtcaa ccattgggat ctcactagtt ggtattgcgg tagcatactt ctacgatatg
    27781 attggaagta aaccacaaga aacaacttca agtagtgatg ttgaggagga tcttgatcta
    27841 tgatgaataa taaagtaact aaagttgaac ttaaaaaagt tttcaaacga agttttatgt
    27901 atggttcttc atggaactat gagagaatgc agaacctagg ttttctatat acaattcttc
    27961 cagtattgaa aaaactatac ccagacaaag attcagcttc tcctgcaatg aaacgtcacc
    28021 ttgagttttt caatactcat caaacagcgg caccatttat tcttggagtt acttccgcta
    28081 tggaagaaca agaaggaaat gaaggtgcag cttcaattac tggtattaaa gttggcttga
    28141 tggggccact ggctggtcta ggagatagtt tgttctggct gacactagtt cctatctgtt
    28201 ttagtattgg tgcgtcttat tctaaagacg gcggtgcttt aggtatcttt atcgccttaa
    28261 tattgtttaa tattattaat attcctgtta aatatttcgg tttgaaatat gggtatacta
    28321 agggttctag tcttatccaa gaaaataata caaaaggaac attgaatcgc gttacgagta
    28381 tggcgacagc attagggcta gtactagtgg gtggtttgat tccatcaatg gttggtatta
    28441 attttggatt agaatttaag cagggggaac ttgttatttc tgttcaagaa atgattacaa
    28501 aattaattcc aggatttatc cctatggctt tgactttatt aatgtgtaaa ttaattagaa
    28561 aaggaaagaa tccggttgta ctaatcttta gtgttatggc tattggagtt atcctagttg
    28621 ttttaggaat tttgaagtag tagaaagtgt ggaggtggta tttgggatat cacctccatt
    28681 ttggaagaga ggtaaagagt gaaattatgg tataagaaag ctgccgcaaa ttggaatgaa
    28741 gccttgccga ttgggaacgg tcatttaggt ggtatgattt atggttcagc tacaaaagaa
    28801 tgtattcaac taaacgatga gactatttgg tatagaggaa agtcagatag aaataatcca
    28861 gactcactat tgcatcttaa aaaaattcgg gaatatcttt tagatggaga aattcagaaa
    28921 gccgaagaat tgataaagtt aacaatgttt gctaccccaa gagatcaaag ccactatgaa
    28981 ttacttgggg aactttgcat tgagcatata gatattcagt cttgtgctct ttcattgtat
    29041 gaaagagagc tagatttaga tacagctatt tctaatgttg tgtttgagcc taatagttgt
    29101 aatttacaaa taaaaagaga atattttacg agttttaata agaatatttt atgttgccgt
    29161 atagtgtcat cagttcaaaa cacattaaat ttaaacatta atttgggtag aaataaacgg
    29221 tttaatgacg aagtatctaa actggattca agtacaattt taatgtcggc ctctgctgga
    29281 ggtagaaaag gtgttcagtt taaagtagta tgtcattcta aggttacgga tggtgaagta
    29341 agtgtattgg gagagacaat agttattcgg aatgctacag aggtatttct ttatctcaaa
    29401 tcaatgacgg attattgggg aaatatagat atttcttctc ttcagggaga atttagtagt
    29461 attgattact ttacagaaaa agatgaacat gtaaaaaaat atcaggagca atttaataga
    29521 gttgatttta aactagacta tagtaaaggt tgtcttagca ttccaacgaa tctacttctt
    29581 gaaaacacta aaaagtatag taactacttg actaacttgt tatttcatta tggaagatat
    29641 ctgttaatat cgtctagtca accgaatggt ttacctgcca atcttcaagg aatatggtgt
    29701 gatgaattaa atccaatttg gggttctaaa tatacgatta atattaatac tcaaatgaat
    29761 tattggatgg taggtccatg tgatttacca gaagtagaat atccattatt tgatatgctc
    29821 gaaagaatga gagaaccggg aagactaacc gctaagaaaa tgtatggagc tagaggtttt
    29881 acagcacatc ataatacgga tggttttggc gatacggctc cccaatctca tgccatgggg
    29941 gctgcaattt gggtattaac tattccatgg ttatgtactc atatttggga acactattta
    30001 tatttccaag atgagcgtat tcttacggaa cattttgaaa tgataaaaga agcatttctt
    30061 ttctttgaag attatttatt tgaggtggat ggctacttga tgacaggtcc aagtgtctca
    30121 ccggaaaata aatatcgctt aaaaaatggt attgaaggaa atgcttgtct atcatctaca
    30181 attgataatc aaattctaag atatttttgt gattcatgca ttggcattgc aaaacaatta
    30241 ggagacaatt cggattttat tagtcgtgtg aaggagttaa aaaagaaatt acctagaaca
    30301 aaaataggta gtaatgggca aatacaagaa tggctagagg attatgaaga agtagagcct
    30361 ggtcatagac acatttcacc tctatttggg ctttatcctt ataatgagat tgatattcat
    30421 aaaactccgg aattagcaga agcagctaaa atcactatca ataggagatt atcaaacgct
    30481 aactttttat cttcacagga tagggagcaa gcgattaata attggttagt aagtggtttg
    30541 catgctagta cacaaacagg ttggagtgct gcatggctga ttcatttttt tgcgagacta
    30601 tatcaaggtg aacctgctta taaccagatt aatggtttgt taaataatgc gactcttggc
    30661 aatttatttc ttgaccatcc accatttcaa attgatggta atttaggttt ggtgagtgga
    30721 atttgtgaat tattagtaca gagccatcat aattggttat cactaattcc agctttacct
    30781 tctgcttggt cagaaggaga agtgaaaggt ttcagagtaa gaggaggata taaggtatcg
    30841 tttgcttgga aaaatgggga tataacattc ctaaaattgg aaggaggaaa caaagatcaa
    30901 aaagtaagag taagaatata tggcaaaaat actgatgtac aaaatattga attggtattt
    30961 aattcagaaa aaattattga gttaaatttt taggtataag tcatgaataa agaaaaaata
    31021 aaaagaaaat taatcacaat attgtttgta tgtattggga tgttatgttt tggattgtta
    31081 gcaggagtta aggctgataa tcgtgttcaa atgagaacga cgattaataa tgaatcgcca
    31141 ttgttgcttt ctccgttgta tggcaatgat aatggtaacg gattatggtg ggggaacaca
    31201 ttgaagggag catgggaagc tattcctgaa gatgtaaagc catatgcagc gattgaactt
    31261 catcctgcaa aagtctgtaa accaacaagt tgtattccac gagatacgaa agaattgaga
    31321 gaatggtatg tcaagatgtt ggaggaagct caaagtctaa acattccagt tttcttggtt
    31381 attatgtcgg ctggagagcg taatacagtt cctccagagt ggttagatga acaattccaa
    31441 aagtatagtg tgttaaaagg tgttttaaat attgagaatt attggattta caataaccag
    31501 ttagctccgc atagtgctaa atatttggaa gtttgtgcca aatatggagc gcattttatc
    31561 tggcatgatc atgaaaaatg gttctgggaa actattatga atgatccgac attctttgaa
    31621 gcgagtcaaa aatatcataa aaatttggtg ttggcaacta aaaatacgcc aataagagat
    31681 gatgcgggta cagattctat cgttagtgga ttttggttga gtggcttatg tgataactgg
    31741 ggctcatcaa cagatacatg gaaatggtgg gaaaaacatt atacaaacac atttgaaact
    31801 ggaagagcta gggatatgag atcctatgca tcggaaccag aatcaatgat tgctatggaa
    31861 atgatgaatg tatatactgg gggaggcaca gtttataatt ttgaatgtgc cgcgtataca
    31921 tttatgacaa atgatgtacc aactccagca tttactaaag gtattattcc tttctttaga
    31981 catgctatac aaaatccagc tccaagtaag gaagaagttg taaatagaac aaaagctgta
    32041 ttttggaatg gagaaggtag gattagttca ttaaacggat tttatcaagg actttattcg
    32101 aatgatgaaa caatgccttt atataataat gggagatatc atattcttcc tgtaatacat
    32161 gagaaaattg ataaggaaaa gatttcatct atattcccta atgcaaaaat tttgactaaa
    32221 aatagtgagg aattgtctag taaagtcaac tatttaaact cgctttatcc aaaactttat
    32281 gaaggagatg ggtatgctca gcgtgtaggt aattcctggt atatttataa tagtaatgct
    32341 aatatcaata aaaatcagca agtaatgttg cctatgtata ctaataatac aaagtcgtta
    32401 tcgttagatt tgacgccaca tacttacgct gttgttaaag aaaatccaaa taatttacat
    32461 attttattga acaattacag gacagataag acagctatgt gggcattatc aggaaatttt
    32521 gatgcatcaa aaagttggaa gaaagaagaa ttagagttag cgaactggat aagcaaaaat
    32581 tattccatca atcctgtaga taatgacttt aggacaacaa cacttacatt aaaagggcat
    32641 actggtcata aacctcagat aaatataagt ggcgataaaa atcattatac ttatacagaa
    32701 aattgggatg agaataccca tgtttatacc attacggtta atcataatgg aatggtagag
    32761 atgtctataa atactgaagg gacaggccca gtcccttttc caacaccaga taaatttaat
    32821 gatggtaatt tgaatatagc atatgcaaaa ccaacaacac aaagttctgt agattacaat
    32881 ggagacccta atagagctgt ggatggtaac agaaatggta attttaactc tggttcggta
    32941 acacacacta gggcagataa tccctcttgg tgggaagtcg atttgaaaaa aatggataaa
    33001 gttgggcttg ttaaaattta taatcgcaca gatgctgaga ctcaacgtct atctaatttt
    33061 gatgtgattc tatatgacaa taatagaaac gaagttgcta agaaacatgt taataatttg
    33121 tcgggtgaat ctgttagtct agatttcaaa gaaaaaggag caaggtatat taaagttaaa
    33181 ttactaacga gtggagtgcc tttgagttta gcagaagtag aggtttttag agaatcagat
    33241 ggtaagcaat ctgaagagga tatagataaa ataacagaag ataaagtagt ctctacaaat
    33301 aaggtagcta ctcaaagttc aaccaattat gagggtgtag ctgctttagc agttgatggt
    33361 aataaagatg gagattacgg acatcattcg gtgactcata ctaaggcaga ttctaacgct
    33421 tggtggcagg tcgatctggg agaagagttt acggtttcta aagttgatat ttataataga
    33481 acagatgccg aacctcagcg tttatctaat tttgatgtta tttttctatc ttcatcagga
    33541 gaagaagttt ttagaagaca ttttgataaa gtagttgatg gtttgttatc tttaaaagta
    33601 ccttctgtag gggctaagct agtcaaaata gaattaaaat cagcagctat tccgttaagt
    33661 ttagcggaag ttgaagtcta tggttcaaag agaactccga agaaactttc taatattgca
    33721 ttaaccaaag aaactcgaca gagttcaacg gattacaatg gtttttctcg tctagcagtt
    33781 gatggaaata aaaacggaga ttatggtcat cattcagtga ctcataccaa aggagattct
    33841 ccttcatggt gggagataga tttagcacaa accgaagaat tagaaaagtt aattatttat
    33901 aatagaacag atgctgaaat tcagagatta tcaaattttg atattattat atatgattca
    33961 aataatcatg aagtttttaa acaacatatt gacagtttag aaagcaataa tctatccata
    34021 gacttaaaag ggctgaaggg aaaaaaggtt agaatttctt tgagaaacgc aggaattcct
    34081 ttaagtttgg cagaggtaga ggtttatact tataagtaat tttaaaaatt atcatcggta
    34141 gtatgaaaga aacagaaaaa taagaggaaa atagtatgat tcaacatcca cgtattggta
    34201 ttcgtccgac tattgatggt cgtcgtcaag gtgtacgcga atcacttgaa gtacaaacaa
    34261 tgaacatggc taaaagtgtg gcagatttga tttcaagcac attgaaatat ccagatgggg
    34321 aacctgtgga atgtgtgatt tctccatcta ccattggtcg tgttccagag gctgcagctt
    34381 cccatgagtt gtttaaaaaa tcaaatgttt gcgcaacaat tacagttaca ccatgctggt
    34441 gttatggtag tgaaactatg gatatgtctc cagatattcc tcatgctatt tggggattta
    34501 atgggacaga acgcccagga gctgtctatc ttgcagctgt actagcttca catgctcaaa
    34561 aagggattcc agcctttggg atttatggta gagatgttca ggaagctaat gatacagata
    34621 ttccagaaga tgtcaaagaa aaacttttac gttatgcgcg tgcagctctt gcaactggct
    34681 tgatgagaga cactgcttac ctatcaatgg gtagtgtttc gatggggatt ggtggttcta
    34741 ttgtaaatcc ggatttcttc caagaatact taggaatgcg aaatgaatcg gtagatatga
    34801 cggagttcac acgccgtatg gaccgtggta tttacgaccc tgaagagttt gaacgtgcta
    34861 tggtttgggt aaaagaacat atcaaagaag gagttgaccg aaatcgtgag gatttgattc
    34921 tttctaaaga agagaaagaa aaacaatggg aatttgttat taagatgttc atgattggac
    34981 gtgacttaat ggttggtaac ccaagacttg ctgaacttgg ttttgaggaa gaagcagttg
    35041 gtcaccatgc tttagtagct ggtttccaag gtcaacgtca gtggacagac cattttccaa
    35101 atggagattt tatggaaact ttcctcaata ctcagtttga ctggaatggt attcgaaaac
    35161 catttgtatt tgcgacagag aatgattcac taaatggtgt gtctatgctc tttaattatc
    35221 tactaacaaa tactccacaa atctttgctg atgtgcgtac ttattggagt ccagaggctg
    35281 ttgaacgtgt aacaggatat actttagagg gtcgtgctgc agctggcttc ttacatctaa
    35341 tcaactctgg ttcttgtaca ttggatggta caggtcaagc tactcgagat ggcaaacctg
    35401 ttatgaaacc attctgggag ttggatgaaa gtgaagtaca ggctatgctt gaaaatacag
    35461 acttcccacc agcaaaccgc gagtacttcc gtggaggagg attctcaact cgtttcttga
    35521 cgaaggggga tatgccagta acaatggtac gtctcaatct tctaaaaggg gttggtccag
    35581 tgctacaaat tgcagaaggt tacacacttg aacttcctga agatgttcac catactttag
    35641 ataatcgtac agattcagga tggccaacta cttggtttgc tccacgtttg acaggaaaag
    35701 gtgctttcaa gtctgtctat gacgtcatga ataattgggg agctaatcac ggagccataa
    35761 catatggaca cattggagca gacttgatta ccttggcttc tatgttgaga attcctgtca
    35821 atatgcataa tgtacctgag gaagatatct ttagacctaa aaattggtcc ttatttggaa
    35881 cagaagatct agaatcagca gactatcgtg catgtcagtt gttgggacca ctacataaat
    35941 aaaacttgtt tatataggag gtgaacttac gtccctccta tccttttaaa aagatttgtt
    36001 aaacaattca caaataattg aaaacgaata caaaaagtaa tataatgatg ttaaatagat
    36061 agcgcggagg cgcaggagga aaattatatg gctatatttt atgttccggc agtcaacctt
    36121 attggaaaag gtgttgtaaa tgaagtgggt ccttatatca aggaacttgg ctataaaaag
    36181 gcacttttgg tgacagataa gtacatcgaa ggcagtgata ttttacctaa gactttaaaa
    36241 ccactggata cagaaggaat cgaatatgtc atctttagcg atgtagagcc aaaccctact
    36301 tgtaaaaatg tcacagatgg ggtagctgct ttgcaagaac atggctgtga ctttatcatc
    36361 agtcttggcg ggggttctcc acaggatgca gctagttgta tttctatcat ggctacaaat
    36421 ggtggaaaac cacaggatta tgaagggctt cataagtctg ctaaaaaagg tttgccagtt
    36481 gtggctatca atacaacggc aggtacatca gcagaaatta ccattaacta tgtgattact
    36541 gatgaagaac gcaaggttaa gatggtaatg gttgacaaga atagccttgc cttgatttct
    36601 gtcaatgacc ctgaactcat gctttccaaa cctaaaggcc tgactgctgc tactggtatg
    36661 gatgctctga ctcatgctgt tgaagctttg gtaacacctg gtgcttatga tgtaaccaag
    36721 aaactgtcta ttggtgctat tgagcttatc aaggaatatc ttcctcgtgc tgtagaaaat
    36781 ggacatgata ttgaagcgcg tgaaggtatg gtcaatgcca tcttccttgg tggtatgagc
    36841 tttaataatg ctggtcttgg ctatgttcac tcaatggctc accaactcgg tgcagtatat
    36901 aatttgccac atggcgtgtg ctgtgccatg ttgctaccag ttatagaacg tgaaaatgct
    36961 aaacgtgtac cagaagcttt ccgcaatgtt gccaaagcct tgggacttca tgtagaaggt
    37021 aaatcagatc aagaatgtgc cgattatgcg attgctgaga ttgagaagct ttctgagaca
    37081 gtaggtattc ctaagaaact gactgaactt ggtattgaag aaaaagattt cgactttgaa
    37141 tacctttcta agaatgcctt gattgatgcc tgcgcaccag gaaatccatt tatgccaacc
    37201 ttagaagaaa cgattgcctt ttataaagag ttattttagc aagagattgg acgacaatag
    37261 gacaattcac ctctaattat tgacatttca ggaaaaatcg cagtaaaaac ggcacagcct
    37321 tctttaaatg tgctataata ctagaaaaat acttgtggag gttccattat ggcaatattt
    37381 ttcatgattt ttctgattgt ttgtgtgctc ctattggtga tagtcacact gagtacagtt
    37441 tatgtggttc gtcagcagtc ggtggcgatt attgaacgct ttgggaaata ccaaaaggtt
    37501 gctaatagcg gtattcatat tcgcttgcct tttgggattg actcgattgc agcacggatt
    37561 cagttgcgct tgttgcaaag tgatattgtg gttgagacta agaccaagga caatgtgttc
    37621 gttatgatga atgtagcgac tcagtaccgt gtcaacgagc agagcgtgac agatgcttac
    37681 tataaactca tacgtccaga atctcagatt aaatcttata tcgaagatgc tcttcgctct
    37741 tctgttccaa aattaacctt ggatgaattg tttgagaaaa aagatgagat tgcccttgag
    37801 gttcaacacc aagtagcaga agaaatgacc acttacggct acattatcgt gaaaaccttg
    37861 attaccaagg tcgaaccaga tgcagaagtt aagcaatcta tgaatgaaat caatgcggcg
    37921 caacgtaagc gggtcgcagc acaagaattg gcggaagctg acaagattaa aattgtcact
    37981 gcagctgaag ccgaagcaga aaaagaccgc cttcatggtg tggggattgc ccaacaacgt
    38041 aaggcgattg tggatggatt ggcagagtct atcaccgaac tcaaggaagc caatgttggc
    38101 atgacagaag aacaaatcat gtctatcctc ttgaccaacc agtatttgga taccttgaat
    38161 acctttgcct ctaaaggaaa tcaaaccatc tttttaccaa atactccaaa tggtgtggat
    38221 gatatccgta cacaaatctt gtcagccctt cgcgctgaga agaaataata gactaatact
    38281 cttcgaaaat ctcttcaaac tacgtcagcg tcgtcttgcc gtatagatgt tactgacttc
    38341 gtcagttcta tctgcaacct caaaacagtg ttttgagctg acttcgtcag tcttatctac
    38401 tacctcaaaa cggtgttttg agcaacctgt agctagtttc ctagtttgct ctttgatttt
    38461 cattgagtat aaagagcttg gcaacaggct ctttttgtat tgcgtttatt aagaaaaaca
    38521 aaaaacatcg atatacattt aactaaaaat tattgtatgt tatctccctt aattaggaat
    38581 gataagggaa taactagaaa gatttgtgaa tacaaactat ttctgatata caaaatatac
    38641 agtaataatg aatgatggga gatgggatga aagaatttca atttgagaga aagcagcgtt
    38701 tttctttgag gaaatatgca ataggagctt gttcggtctt gctaggaacg agtttatttt
    38761 ttgctggtat gggtgctcag cctgtacagg atacagaaac gagttcagca ctaatttcaa
    38821 gtcattattt ggatgagcag gatttatctg aaaagctgaa atctgagttg caatggtttg
    38881 aattagaaaa caagcttttg aacttatggg agcattaggt tactatgaag gatttgttcc
    38941 ttatgtttca aatcaatacc aaaaccaagc tgaagaagaa tacaaaccgc tatctgataa
    39001 atatattttc gaaaaaatct taggaaaaac atatgcagcc ttcaaaaaag atcaaattaa
    39061 tgagcgtgtc gagaaattag gtaagttaaa acctattaca ataaattaca acggaaaatc
    39121 agaagtaatt gatagtaaag aaaaattaca agagcttatg aataaagccg ttaaagacga
    39181 agtggctcaa atatagtaaa atgaaataag aacaggacaa atcgatcagg acagtcaaat
    39241 cgatttctaa aaatgtttta gaagtagagg tgtactattc tagtttcaat atactataaa
    39301 atcaggcaat accacggcta aaaagtttga gtttatcgaa ataccagtgc aaaaactgaa
    39361 aaaagcaatt tataaagctc atctcaaaga ttcagatgac tttagaccag aaacatccac
    39421 accaaatctt tttgaaagct gtttgaagct ttgtccttgc tttcttagtt catagatctg
    39481 aactttatct tcataactca atttcataat aaaacacccc aaaagttaga tttattctgt
    39541 ctaacttttg gggtgcagtt cattaatcgg tcgatttttt ttgtagaaac agttgcctga
    39601 ttaagttgca agtcgataga cggcttcggc ataaatatcc atagcacggt acaaatcttc
    39661 tagaacggca cattcatttg cctgatgttc tgtctgcttc gctcctggga ataaggcgcc
    39721 gaaggctaca caatttggca tggtgcgagc aaaagtggca ccaccggatg aaatagcagg
    39781 actgttatcg ccagtctttt cttggtagat ttgcatcagt gtgctaacga gtttactgtc
    39841 ttttgcgacg tatagaggcg ctagatagtc aaactcttcg tagcggagtt ggtagttttg
    39901 tgcacatctt gtaagcaact ctactagttc ttccttgtca gctaagacag gagtccgaat
    39961 gtcaatacgg atttcagaac gttcatgatt gatcatgaga cctgcgacat taaaggatag
    40021 gtgaccagaa ggttcatctg ctatatcacc aaagatttgt cttcctgtgc cgtcttgacc
    40081 tgcttgtgtt gcaagaaaac tgagagcagg gtgttcttgg agaggagcaa gaatggtagc
    40141 tagtcggatg acagcattga taccttgact agcatcctta gcatgctttg gcactccgag
    40201 aaccgttacg gtttgttcag tggtttggta atcataacca gcttctttga gaccgttaca
    40261 aacctgttca tagaggagac cttggtagtt ggccttgtct ggtacaacgt taaaggcgcc
    40321 tcctacttca agctctagtt gatccgatcc cgggccatga agtttgacct gtagaagccc
    40381 tttttcagca taggtcagag gaaaagatga gtcaggtgca aagcccatac tggcctgttc
    40441 ttcgatggta ttgtagcgtg ccatgcagcg ccagagggtt tcctcatcgg taccaaagat
    40501 aaagcgtacg cgctttttga actgaatacc ttggtccagc aagcttttta ctgcatagag
    40561 agctgcgagc gaagggcctt tatcatcttg gacaccacgt ccgaataccc agccgtcttt
    40621 gatagttgct tcaaatggcg gtgtctgcca atctgcttca tcacctgatg gaacaacatc
    40681 caaatgacag agaatggcca gaagctctgc tccctgaccg atttctgcat atccgtaata
    40741 acctttaggg tcaagatagg tagtgaaacc tatgtctcga caaatctcta aagttttttc
    40801 taggacatct tggattgctt gtccaaaagg tgttccattt tctccttcat tgagtactga
    40861 aggataggaa atcaaggttt ttaatgatat aagaaattca tctttaactt gatttgttat
    40921 atctattttc atggaatcac ctcactcact attttatagg aatggaagga aggttccaag
    40981 gagaagaagg gcgatggtca ctacaataat agcgactacg agtttgccca tgaatttcca
    41041 ccaagtacca atgttgatac gtccaagtgc aagagctccc atcacaatac cagatgttgg
    41101 tgcaatcaag ttcaagacac ctgaagcaga ttggtaagca gtgataatca agctaggacg
    41161 gacatttaca aattctccaa gtggagccat gatacccata gttgcgctgg caagaccaga
    41221 tgaagatggg atcaagaatg acataggtag atagaagata taagttacaa cgataaagac
    41281 ttgtgaagat agaccgctca agccttcttt accccagttg aggattgtat cggtaatcat
    41341 accgtcgttc atgataactt gaataccacg agcaatcgct acgatcaagg caacactgag
    41401 caagtcagca gcaccattca tgaaggaaga gataatctta tcttctttaa gaccataaat
    41461 aacaccaatc aggataccca taaaggcaaa gagcatggcg ccttctggga agtaccaagt
    41521 acctagtgca gaagtagatg aaccgacaat attaccaata actggaagac cagtcaacca
    41581 agcattaaag tcatcaaaaa tggtaacgcc aaggtctgtc catggaatga agctcaatac
    41641 catcaagatg aatgtcaaca caaataagaa gagaactgat ttttgtttgc tgctaagtgt
    41701 agattctaca gatgaagatt cttctacgtt aaagtgtttc aaatcttctt tgcgagtact
    41761 ataaaccagt gacttagtcg gatctttttg aatcttatcc gcataacggt aaacaaacca
    41821 agtactaaga gcagtcaagg taacccagaa aatcagacga agtacgatac cgtcccctgt
    41881 accaactccc gcagtcgctg aagcaatacc tgtcgcaaat ggattcagag tagatgccaa
    41941 acagccgatt tgagaaccga gcaaaataat tgcaacacca gtcaggctat caaaaccaac
    42001 ggccatcata actggcacaa ggagtggata gaaggccatt gtttcttccc ccataccata
    42061 agttgtacca ccgagggcaa acaaaggcat cagtaccaaa attaacattt tttcgcggcc
    42121 cttatacttc ttcacgatag aggcaatccc tacgtcaaga gcaccagttt tgttgacaat
    42181 gccaaggaaa ccaccaacca taaggatgaa gaaggctaca tcaatcgctg cgctcgtttc
    42241 tttaatgagc gaaccttcct ctggatgagt acctagcata gcccgaatcg gtgccatgag
    42301 gacatcccaa atcccttgtg gattttgagg ctgagcctcg taaatacctt ctataaaggc
    42361 ccccgcaggg ataaaccaag ttagcactgc cataatagca atgattatca ataatacggt
    42421 gtaagatgaa ggcatcttaa accctttttt agctttttca ctcatttgtt tttcctcctg
    42481 atgtctaaca aagtgtaaaa aaccaactac tttcttaaat aaacatttaa gaaaacgctt
    42541 tctatttata tttgttttac catattaaag tctaaaaaac taatatcttt tgaaatattg
    42601 tacatgtttt caagaataat ttctaatttg atataaagat actagaaata gaatacatct
    42661 tattagtaaa acaacttatc ctttttcaat aattgttccg ctttcagatt caatcaaggc
    42721 gcctagattt tcaagggaag taataactgc ttttccttct ggacgaccat tgacaaaagc
    42781 gatagctgct tctacttttg gaagcatgct acctggtgca aactgatctt gtttgatata
    42841 ttcttccagc tgggcaacat tcacatgttc caatttttcc tggtttggct tgttgtagtt
    42901 aacaaataca taatctacac ctgtcaaaac gatgaagagg tctgcatcaa ccaattctgc
    42961 caaacgttgg gaagcgaagt ctttatcaat aaccgcttcg acaccagtca aatgtccatt
    43021 gttttctttg acgacgggaa taccgccacc acctgcagct acgacgactt gaccattatt
    43081 taaaagagta cggatggttt caatttcttt gatgtcaaca ggttttggtg aggcaacgac
    43141 cttacgccag ccacggccag catcttcctt gaaagtcgct ccgctctttt cggcttctgc
    43201 ttttgcttct tcttctgaat agaaaggacc gattggttta ctcaagttaa caaaagctgg
    43261 atcattttta tctacgacaa cttgcgttac aacagaggca acattttttt cgatgccttc
    43321 atccaagaga gcattttgca aagcattttt caaccagaaa ccgatgctac cttctgtcat
    43381 agcgacaagt gagtcgagtg ggaaggcagg gttcttttca gagtctgatg ccaaatgttg
    43441 gagcaagaga ttcccaactt gaggtccatt accgtgagtg ataatcagat catctccatt
    43501 tttaatcaat tttacaagat gcttagctgt ttcaactaaa gcttcttgtt gagcctttgc
    43561 tgatgggtca gaagaaagaa tcgcatttcc tcccaaagct actacaattt tacgatttgc
    43621 cataaattct cctttatcac actcaataga atgcgtttag atttcaattt aatgattttt
    43681 cacatatttt ataagaaata atagattacc attatataaa agaggaccgg actaaagcta
    43741 ttagtcgcag ccctcatagc tgttggtaga cggtttatta tctaaaatta tactttagga
    43801 atataaaggt taccaagtgt agcagccata acagctttga tagtgtgcat acggttttct
    43861 gcttgatcga agtggcgagc gtacttgctg cggaagactt cgtctgttac ttccatttct
    43921 tctacaccaa atttttcagc aacgtcttta ccataaacag tgtgagtatc gtggaatgct
    43981 ggcaagcagt gtaggaagat caagttttca ttgcctgctt ttttaactaa gtccatattg
    44041 acttggtaag gtttaagaag agctacacgt tctgcgaatt tgtcttcttc acccattgat
    44101 acccaaacgt ctgtgtaaag aacgtctgca tctttaactg cttcatcagc atcttcagtg
    44161 atgagaacat gtgcgccact ttctttagca aatccttctg ccaattcaac gatttctttt
    44221 tctgggaaga gttcttttgg tgagaagatg tgaacattga caccaaggat agcacctgtt
    44281 acgagcaagc tgttggcaac attgttacgt ccatcaccac agtataccaa tgtcaagcct
    44341 tccaagcgac cgaagttttc ttgaacagtc aagtagtcag cgagcatttg agttgggtgc
    44401 cattcgtcag ttagaccgtt ccatactgga acgcctgaga attctgccaa ttcttcaacc
    44461 atacgttggc tgaatccgcg gaattcaatc ccgtcaaaca tacgtcccaa tactttagca
    44521 gtatcttcag tagattcttt tttacccaac tgaatatcat ttgctccgag gtattctggg
    44581 tgagcaccaa ggtcgatagc cgcagttgta aaggctgcac gagtacgagt agatgttttt
    44641 tcaaatagga gagcgatatt cttgccagca aggtagtggt gttgaatatt gcgttttttc
    44701 aaatctttca agtgagctga aagaccaata aggtattcta actctgcacg ggtaaagtct
    44761 ttttctgcta agaagctgcg tccttggaat actgaatttg tcattttatt atttcctctt
    44821 tctatttttt acattttcta ttgacgaata ccgaacagcg attacacttc ttcacgttca
    44881 aatggcatag acatacaacg aggtccacca cggccccgaa ccaattcact tccgcgaatc
    44941 ttaatcaagc gaagcccgta ttcttccaaa atcttattgg tcacggtatt gcggtcataa
    45001 acaactacca caccaggtgc gatggtcaaa gtgttagaac cgtcgttcca ttgttcacgc
    45061 gcagctgcta cgatattgcc accaccgcaa cgaatcaaat gaactttttc tacaccaagg
    45121 ttttgagcaa gaagttcagc taagtcacct ttctcttcaa caattttaag tttttcgttt
    45181 tcgtaagtaa ctgagtaaac gtgaaggtcg ccttcgattt ctgggtgaat agtgaacttg
    45241 tcatagtcta ccatagtgaa gacagtatcc aagtgcatga atttacggtt gttagcaaat
    45301 tcaaaggcca aaactttctt gaagccaaca tttttcttga agatgttgac caaaagtttt
    45361 tcgatagaag ctgcgtctgt acgttgagag atacctactg caaggacgtc tttagaaaga
    45421 actagctcgt ctccaccttc gatacgcgta tcttcttcac ggttgtagac caaatccact
    45481 tttccgccat agattgggtg gtatttgaag atatacttac cgtagagtgt ttcacggtta
    45541 cgagtgtctg caaacatgtg gttaagcgat acggcgtttc caattgttgc aaatgggtcg
    45601 cgagtgaaat agaggtttgg catcgggtca attgcaaatg gataatctga ttcaactaag
    45661 tcagttagat ctttagcttc gtcaggaatt tctggcaatt caactttttg aatcccagcc
    45721 attgtttttt caaccaattc ttggttgtcc ttgatgccgt gaagcaattc acgaatagca
    45781 accttagttt gacgatcacg gatgttggct tcgtctaagt attcctcgat aaattgatcg
    45841 cggatttctg gagaggtcaa tgattcagca gcgagttgtt ctaggtagag aacctcaatt
    45901 ccttcatcgc gaagagcttg ggcaaatgca tcatgttctt tttgagcatc ttccaagaaa
    45961 ggaatatcat caaaaagaag cctttcaaga tagtccggca acaagttttc taactccttg
    46021 cctggacggt gcaacataac ttttttcagt ttcccaattt ctgagaagac ctgaattgga
    46081 tgtgaagaca tgtattttcc tccttaaaaa ttttgacttg gcaccatttt gggtaccgct
    46141 tacatgtatg ttataacgca attcctaggt aatgtcaatg gctataattt ctcggaaaat
    46201 aatataaatt atgatattta gcacaatttt atgttattat acacaacata ggatggaata
    46261 catatataca aatgcataaa cttctattaa agaggatata aaattttttt aaaaaatttt
    46321 tcaaaaaata cacaaataac caaaaagtgt ccaattatca tctggttatc acttggatct
    46381 gtataaagag aaatgtttgt gtgaaaggat aaaaagatgc aacattcttt tgaagataga
    46441 ttttggagaa gcatttcttg ttcaattgta caaattatag aatcttttct gagtatttag
    46501 gaagagataa ttatcttatt gaccctcttt ttattttttg ttatagtcga cgaggtgata
    46561 gtttagaata atcacttatt cacaatctgt ggaaaagtct ggagagtgaa tggtcttcac
    46621 acaatgacct gaaagaagcc tgagaataat tatggagagt agcattctga gaggtgttag
    46681 cagaaccata tgacagagct gtttgaagag ggaatattga ggagaaaaat cctgagccta
    46741 ccagttggag ttggaaagag ctggctgtta gatcatggtt tattatccac aacctgtgga
    46801 taaccttgtg aacaagagaa gttgcaaaag aaggagatat ataacgatga agaaaatcaa
    46861 accgcatgga ccgttaccaa gtcagactca gctagcttat ctgggagatg aactagcagc
    46921 ctttatccat tttggaccta atacttttta taatcaggaa tggggaacag gtcaggagga
    46981 tcctgagcgc tttaacccga gtcagttgga tgcgcgtgag tgggttcgtg tgctcaagga
    47041 aacgggcttc aaaaagttga ttttggtggt caagcaccac gatggctttg tcctttatcc
    47101 gacagctcac acagattatt cggttaaggt cagtccttgg aggagaggaa agggcgactt
    47161 gctccttgaa gtatcccaag ctgccacaga gtttgatatg gatatggggg tctacctgtc
    47221 accgtgggat gcccatagtc ccctctatca tgtggaccga gaagcggact acaatgccta
    47281 ttatctggct cagttgaagg aaatcttatc aaatcctaac tatgggaatg ctggtaagtt
    47341 cgctgaggtt tggatggatg gtgctagagg ggaaggggcc cagcaggtca attatgaatt
    47401 tgaaaaatgg tttgaaacca ttcgtgactt gcagggcgat tgtttgattt tttcaacaga
    47461 aggcaccagt atccgctgga ttggcaatga acgagggtat gcaggtgatc cactgtggca
    47521 aaaggtgaat cctgataaac taggaacaga agcagagctg gactatcttc agcacgggga
    47581 tccctcgggc acgatttttt caatcggaga ggcagatgtt tccatccgtc caggctggtt
    47641 ctaccatgag gatcaggatc ctaagtctct cgaggagttg gtcgaaatct actttcactc
    47701 agtagggcga ggaactccac tcttgcttaa tattccgccg aatcaagctg ggctctttga
    47761 tgcaaaggat attgaacgac tttatgaatt tgcgacctat cgcaatgagc tctataaaga
    47821 agatttggct ctgggagctg aggtatctgg tccagctctt tccgcagact ttgcttgtcg
    47881 ccatttgaca gacggccttg agaccagctc ttgggcaaac gatgcagact tgcccatcca
    47941 gttagaactc gacttaggtt ctcctaaaac ttttgatgta attgagttaa gagaagattt
    48001 gaagctaggg caacgaatcg ctgcttttca tgtgcaagta gaggtggatg gtgtctggca
    48061 ggaatttggc aggggcttca cagttggtca taagcgcctc ttgcgaggtc cgctagtaga
    48121 ggcacagaag gtgcgcgtga tgattaccga ggcacaatct attcctgtat tgaccaagat
    48181 ttccctttat aaaactcctg gattatcaaa aaaagaagtt gttcaggaac tagcatttgc
    48241 agaaaaaagc ctagctgtgg caaagggaga aaatgcctat tttacagtta agcgcagaga
    48301 atgtagtggt cctttagaag ctaagatttc gattcaaccg gggacaggtg tccatggtgt
    48361 cgcctatcag gatgagattc aagtccttgc gtttcaagct ggtgagactg aaaaaagtct
    48421 gacgctacca accttgtatt tcgcaggaga taaaaccttg tatttctatc tgaacctaac
    48481 ggtggatggt cagcttgtgg atcaacttca agtccaagtt tcataaaaga agaacctttg
    48541 cgcgatgcaa aggttctttt ggttattagt gacttggtaa ccagctgagg gtgaaagtta
    48601 gttgttcagc ttttaagagg tcttggtgtt gaatagttga tacgagtatt ttgtccagtc
    48661 ggcattcttt gacaaagtta aaatggttgt ggttttgttt agtatggata tccagccatt
    48721 tatcttcttt agctaggtag actcgtagat ggtcaaagag agggattccg aggtcatagc
    48781 ttggttttcc tggacaggtt ggataaaatc cgagagctga ccagatgtac caagcagaga
    48841 gactaccatt gtcttcatct ccaggatagg cttcccaact tgggtgaaaa gctttctgac
    48901 ggagcgtctt gataagaagg gcagtgtagt cagggtaatc gctgtagcgg aagagataag
    48961 gaatgtggaa actaggctgg ttggaaatgg ctatttgtcc aaaaggagca gtagccatct
    49021 cgctcatttc gtgaatttcg taaccatagc ctgttgtttc aaagagggga gcatcttgac
    49081 aggctttcaa aagatagttg ctaaaggttt cttttccacc catcagttgg attaagccag
    49141 ggatgtcgtg gagaacgcct aaagtagctt gaatggcaga gcattcagcg tagtctcgcc
    49201 cccaactata aggagagaag tcagggtgaa agtttccttg attgtctcgt gctcgcatgt
    49261 aacctgtctc agcgtcaaat agctggcggt aattttgtga agcagccttg taggtttcag
    49321 cgatttctat gttctctagt tttttggcac agctggcgat acaaaagtca ctataggcat
    49381 agtctagagt atggctaaca ctttcatggt ggtcggtaga gaggtaacct agttcttggt
    49441 attgggctag tccgtggcgg ccattgatgc cgagagggtc ggctttgctg gctgtttcga
    49501 gcatggcttg gaagagttct ccttctaggt caggggccat gtccttgcag gcgctatctg
    49561 cgataatacc gtctaaaagt gtacctggca tcataccccg ttcatctgga gccagccatt
    49621 ttggaaggaa accagtatcg cggtagctat tgaggaaacc ttctaaaaag cgttgatagt
    49681 gctccggtat gataagggca aagaggggga aggtggtgcg gaaggtatcc cagaaaccat
    49741 tgttgctaaa gaggacacca ggcttgacag taccagtagc cagatccatg tggatggctt
    49801 gccctgactc atcaacctca taaaaagtct gtgggaagag gaagagtctg tagaggcagt
    49861 ggtcaaagaa ggttcggtca gcctctcctg tctctataat gtcaaaacga tggaggagat
    49921 tttcccaatc cgcttgggca cttgatttac agctatcaaa atcttcttga ggtagattga
    49981 ttagagcttg agaaggagag atgaaagaag tggctagttg catctcggtt tgactactta
    50041 ctaagtcaat tcgccagtct ccagcttctt ggctgatagc aagaatatcc gtgttcattt
    50101 gcagggcagt gaacatcgtt agcgaatttt tgttagtttc agttttacct tcttgtcgca
    50161 gggcaagagt ccgcttatct acttgctcta ctgtcagttc atctgctgcg tgaagataga
    50221 gggagagggc tttgccttgc ttttgattca aacgaataga agcaccatag caagttggtg
    50281 tgagctgggt ttcaatctga taacgcagag aaaagagctt caaatagtga ggctggaagc
    50341 aagctttatc tatatcataa gaagactggc ggtgaaagag gctgtctccc cccagttgac
    50401 tggtgacagg tgtcagaagg agccaagagt agtccccaat ccaaggactg ggctggtgag
    50461 ttaatcgaat cccctgaaag ataggcagat gcggatcaaa aaaccaagat ccatcctggt
    50521 cactggtctg gggcacaaag taattcatcc caaaaggcac gcctgtgtat ggcagggtat
    50581 ttccccaaga gaaggcatgc ttgctagcag taccaaagcg ggtatcgatg gtttcaagta
    50641 gtggtttcat agtctttcct ttagctgttt ttctacatta tatcagaaaa agagggcctt
    50701 tagaaaagga gtttcaaaaa taactatttt gtagaaaaat gactatcatt tgtgtatgta
    50761 ttttctgtct caaaagctat atactgaaca tgaaacttgt ttgaaagagg gaattgcacg
    50821 atgatttatc cgaaagaaat tgttagagaa tggctagatg aagtagcaga gcgggctaag
    50881 gaccatccag agtgggtgga tgttttcgag cgttgctaca ccgatacctt ggacaatacg
    50941 gttgaaatct tagaagatgg ttcaactttt gtcttgactg gggatattcc tgctatgtgg
    51001 cttcgggatt cgacagccca actcagaccc tacctgcatg tagctaaaag agatgccctc
    51061 ctgcgtcaga ccattgcagg tttggtcaaa cgtcagatga ccttggtact caaggatcct
    51121 tatgccaatt ccttcaacat agaggaaaac tggaaggggc accacgagac cgaccacacc
    51181 gaccttaatg gctggatttg ggaacgcaag tatgaggtgg actcgctttg ctatcctttg
    51241 cagttggctt atctcctctg gaaagaaact ggcgagacta gtcagtttga tgagactttt
    51301 gtcgcagcga ctaaggaaat tctccatcta tggacagttg aacaagacca caagaactct
    51361 ccttatcgtt ttgtccgaga tacggaccgt aaggaagaca ccttggtaaa tgatggcttt
    51421 ggacctgact ttgcagtgac aggtatgact tggtcagcct ttcgtccgag tgatgactgt
    51481 tgccagtata gttacttgat tccgtcaaat atgtttgctg tagtagtctt gggttatgtg
    51541 caagaaatct tcgcagcatt aaacctagct gatagccaga gtgttattgc tgatgccaag
    51601 cgtcttcagg atgaaatcca agaaggaatc gaaaactacg cttacaccac caacagcaag
    51661 ggcgaaaaga tttacgcttt tgaagtagat ggcctaggaa atgccagcat catggatgat
    51721 ccaaatgtac caagtctact agctgcgccc tatctgggct actgttcgat cgatgatgaa
    51781 gtgtatcaag ccactcgccg taccattctg agctctgaaa atccatactt ctaccaagga
    51841 gaatacgcta gcggtctcgg aagttctcat accttctatc gctatatctg gccaatcgcc
    51901 ctttctatcc aaggattgac aacaagagat aaggcagaga aaaaattctt gctggatcag
    51961 ctggttgcct gcgatggtgg tacaggtgtc atgcacgaaa gcttccacgt agatgatccg
    52021 accctctact ctcgtgaatg gttctcctgg gctaacatga tgttctgtga gttggtcttg
    52081 gattacttgg atattcgcta aggggctcgc tttagctcaa ccgattctta tcagaatcac
    52141 aagtttacat ttaaaacgtt aaaatttaaa tttagaatga ggttttactt catggaaaat
    52201 gttgttgtac atattatctc acatagtcac tgggaccgtg agtggtactt gccttttgaa
    52261 agccatcgta tgcagttggt ggaattgttt gacaatctct ttgatctctt tgaaaatgac
    52321 cctgagttca agagtttcca cttggatgga caaactattg tccttgatga ctacttacaa
    52381 attcgccctg aaaatcgcga caaggtccaa cgctacattg acgagggcaa acttaaaatt
    52441 ggtccctttt acatcttgca ggatgactac ttgatctcca gtgaagccaa tgtccgcaat
    52501 accttgattg gtcaacaaga agctgccaaa tggggtaaat caacccagat tggctacttt
    52561 ccagatacct ttggaaatat gggacaagcg cctcaaattc ttcaaaaatc aggcattcac
    52621 gtggcggcct ttggtcgtgg tgtgaagccg attggatttg acaaccaagt ccttgaagat
    52681 gagcagttta catcccagtt ttcagaaatg tactggcagg gtgtggatgg tagtcgtgtt
    52741 ttaggtattc tctttgccaa ctggtacagt aatgggaatg aaatcccagt tgacaaagat
    52801 gaggccttga ccttctggaa acaaaaattg tcagatgtgc gtgcctacgc ttcgaccaac
    52861 caatggttga tgatgaacgg ctgtgaccac cagcctgtac agaaaaatct gagcgaagcc
    52921 attcgtgtgg caaatgaact cttcccggat gtaatctttg ttcatagttc ttttgatgaa
    52981 tatgttcaag ctgtagaagg tgcgcttcct gaacacttat caactgttac aggcgagttg
    53041 accagtcagg aaacagatgg ctggtacaca cttgccaaca cttcttcatc ccgcatttac
    53101 ctaaaacaag ccttccaaga aaatagcaac ctcctagagc aagtggtaga acccttgact
    53161 attatcactg gtggacacaa ccacaaggac cagttgacct atgcttggaa aacacttttg
    53221 cagaatgcgc cacatgatag tatctgtggc tgtagcgtgg acgaagttca ccgcgagatg
    53281 gaaacgcgtt ttgccaaggt caaccaagta ggaaactttg ttaaaagtaa tttgctcaac
    53341 gagtggaagg gtaaaattgc tacggataag gctcaaagtg actatctctt tactgtcatt
    53401 aacacaggct tgcatgataa ggtcgatact gtcagcacag tgattgatgt ggcgacttgt
    53461 gatttcaagg aattgcaccc aacagaaggc tacaaaaaga tggctgctct tatcttgcca
    53521 agttaccgtg tggaggactt ggatggtcgt cctgtagagg ttacaatcga agacctcgga
    53581 gctaattttg aatacgattt accaaaagat aagttccgcc aagctcgtat tgctcgacaa
    53641 gtgcgcgtga ccattccagt tcacctagca ccgctttctt ggacaacctt ccaattgctg
    53701 gaaggagaac aagaacaccg tgagggtatt taccaaaacg gagtgattga tacaccattc
    53761 gtaacggtga gtgtggatga caacatcaca gtctatgata agacaactca cgaagcctat
    53821 gaagatttta tccgcttcga agaccggggt gacatcggaa acgagtatat ctatttccaa
    53881 ccaaaaggaa cagagccaat ctttgcagag cttaagggcc acgaggtctt ggaaaacaca
    53941 gatcgctatg ctaaaatctt gctcaaacat gaattgaccg tgcctgtcag tgcggatgaa
    54001 aagctagaag aagagcaaca aggtatcatc gagtttatga agcgtgaggc tggacggtca
    54061 gaagaattga caaacattcc tctggaaact gagttgattg tctttgttga caatccacaa
    54121 atccgcttca agactcgctt tactaacact gccaaggatc accgtatccg tctcttggtc
    54181 aagactcata acacgcgtcc aagcaatgat tctgaaagta tctatgaggt ggtgacacga
    54241 ccaaacaaac cagctgcttc atgggaaaat cctgaaaatc ctcaacacca acaagctttt
    54301 gtcagtctgt atgacgatga aaaaggggtg actgtatcca acaagggatt gaatgaatac
    54361 gaaatccttg gggataacac cattgccgtg accattttgc gtgcatcagg tgagctaggt
    54421 gactggggct acttcccaac gccagaagca caatgcttgc gtgagtttga agtcgaattt
    54481 gcgattgaat gccaccaagc ccaagaacgc ttctcagcct atcgtcgtgc caaagccttg
    54541 cagacaccgt ttaccagcct tcagcttgct agacaggaag gaagcgtggt tgcgactggt
    54601 agcctcttga gccattctgt tctcagcata ccgcaagttt gtccaacagc ctttaaagtg
    54661 gcggaaaatg aagaaggcta tgtcctccgt tactataata tgagtcaaga aaatgtgcgc
    54721 atatcagaac atcaacaaac cattcttgac ttacttgagc gaccatatcc agttcattca
    54781 ggactattgg ctccacaaga gattcgtaca gaattcatca aaaaagaaga aatttaattt
    54841 caaaaagtaa acatcaaaag aaaggagggg cgaaaaagta agaactaact gctgattcgc
    54901 ccctttttat ggtaaaaaca atgaccattg caacgattga tatcggaggg actgggatta
    54961 agtttgccag tctgactcct gatgggaaaa tactggataa gacaagtatt tcaacgcctg
    55021 aaaacttgga ggatttacta gcgtggctag atcaacgctt gtcagaacag gattacagtg
    55081 ggattgctat gagcgttcca ggtgcggtca atcaagagac aggtgtgatt gatggcttca
    55141 gtgcggtgcc ctacatccat ggcttttctt ggtatgaggc gcttagctct tatcagctac
    55201 ctgtccattt agaaaatgat gccaactgcg ttggactcag tgaactacta gctcatccag
    55261 agcttgaaaa tgcagcctgt gtcgtgattg ggacagggat tggcggagcc atgattatca
    55321 atggtagact ttatcgaggt cgccacggtc tgggtggaga atttggctac atgacaaccc
    55381 ttgcccctgc tgaaaaactt aataactggt cgcaactagc atcaactggg aatatggtac
    55441 gatacgtgat tgaaaaatct ggtcatactg attgggacgg tcgcaagatt taccaagagg
    55501 ccgcagctgg taatgctctt tgtcaagaag ccattgagcg catgaaccgc aatctgacgc
    55561 aaggcttgct caatatccag tatctgatcg atccagatgt catcagtctg ggtggctcta
    55621 tcagtcaaaa tccagatttt atccaaggtg ttaagaaggc tgttgaagac tttgtcgatg
    55681 cctacgaaga atacacggtc gcaccagtta tccaggcctg cacctatcac gcagatgcca
    55741 atctctacgg tgcccttgtc aactggctac aggaggaaaa gcaatggtaa gatttacagg
    55801 acttagtccc aaacaaacgc aagctattga ggttttaaaa ggtcacattt ctctaccaga
    55861 tgtggaagtg gctgtcactc agtctgacca agcctctatc tctatcgagg gtgaggaagg
    55921 tcactatcaa ttgacctacc gcaaacctca ccaactttat cgtgccttat ccttgttggt
    55981 aacagttcta gcagaagctg ataaagtaga gattgaggaa caagcagctt acgaagattt
    56041 ggcttacatg gttgactgtt ctcgaaatgc ggtgctgaat gtggcttctg ccaagcagat
    56101 gattgaggtc ttggctctca tgggctactc aacctttgag ctttacatgg aagacactta
    56161 ccagattgaa ggacagcctt actttggcta tttccgtgga gcttattcag cagaggagtt
    56221 gcaggaaatc gaagcctatg ctcaacagtt tgacatgacc tttgtaccat gcatccagac
    56281 cttggcccac ttgtcggcct ttgtcaaatg gggtgtcaag gaagtgcagg agctccgtga
    56341 tgtagaggac attcttctca ttggcgaaga aaaggtttat gacctgattg atggcatgtt
    56401 tgccacgttg tctaaactga agactcgcaa ggtcaatatc gggatggacg aagcccactt
    56461 ggttggtttg ggacgctacc tgattttgaa cggtgttgtg gatcgtagtc tcctcatgtg
    56521 ccaacacttg gagcgcgtgc tggatattgc tgacaaatat ggtttccact gccagatgtg
    56581 gagtgatatg ttcttcaaac tcatgtcagc ggatggccag tacgatcgtg atgtggaaat
    56641 tccagaggaa actcgtgtct acctagaccg tctcaaagac cgtgtgactc tggtttactg
    56701 ggattattat caggatagcg aggaaaaata caaccgtaat ttccgcaatc atcacaagat
    56761 tagccatgac cttgcatttg cagggggagc ttggaagtgg attggcttta cacctcacaa
    56821 ccattttagc cgtctagtgg ctatcgaggc taataaagcc tgccgtgcca atcagattaa
    56881 agaagtcatc gtaatgggtt ggggagacaa tggtggtgaa actgcccagt tctctatcct
    56941 accaagcttg caaatctggg cagaactcag ctatcgcaat gacctagata gtttgtctgc
    57001 gcatttcaag accaatactg gtctaacggt tgaggatttt atgcagattg accttgccaa
    57061 cctcttacca gacctaccag gtaatctcag tggcatcaat cccaaccgct atgtctttta
    57121 tcaggatgtt ctctgtccga tacttgaccg acacatgaca cctgaacagg acaagccaca
    57181 cttcgctcag gcggcgggaa ctattgctga cattaaagaa aaagctggaa actatgctta
    57241 tctctttgaa actcaggccc agttgaatgc tattttaagt agcaaagtag atgtgggacg
    57301 acgcattcgt caggcctacc aagcggatga taaagaaagt ttacaacaaa tcgccagaca
    57361 agaattacca gaacttagaa gccaaattga agacttccat gccctcttta gtcaccaatg
    57421 gttgaaagaa aacaaggtct ttggtttgga tacagttgac atccgtatgg gcggactctt
    57481 gcaacgcatc aaacgagcag aaagccgtat cgaggtttat ctggctggcc agcttgaccg
    57541 catcgacgag ctggaagttg aaatcctacc atttactgac ttctacgcag acaaggattt
    57601 cgcagcaact acagctaacc agtggcatac cattgcgaca gcttcgacga tttatacgac
    57661 ttaatactct tcgaaaatct cttcaaacca cgtcagcttc catctacaac ctcaaaacag
    57721 tgttttgagc agcctgcagc tagcttccta gtttgctctt tgattttcat tgagtataaa
    57781 aacaagaaca ccttgcttgg cgcagggtgt ttcgcgtgaa acagaagaat tatctggttt
    57841 caaatgctac agttagacaa acttatgata aaatagcaga aagtgaatgt ttcctaagag
    57901 caattctatc gatgagcaat tggaggtatt atgctacact taaaattagt aaaacaagaa
    57961 atagaagctg aaaagccagc atctgtagaa gcttggatca tttccgtcaa atttaaaaaa
    58021 ggttgctacc gacatatata gattccaaaa acaaaaacgt tagcggaact agcagatgtg
    58081 attttatggg gttttgattt tgcaaatgat catgctcacg catttttcat ggataatgtt
    58141 gagtggagtc atgcagattc ttactttctt agctttgtta gtgacgatgt tgaagaacgt
    58201 tacacagaaa atgtctatct ggatagccta agtgtcaaac aaaaatttaa gtttattttc
    58261 gacttcggtg atgaatggcg ttttgaatgc caagtactga gagaaatcga gacagaggac
    58321 gaagaagctt atctcgtacg ttcggttgga acgtcgccag aacaatatcc agattatgat
    58381 ggttttgact atgaagaatg gtaaaattga aatctaaaaa acaattggaa tcagtctgtg
    58441 taggcttagt atttcaatag acttcctgca aaactagaat cctaattcat gattgataat
    58501 accagcactc
//
LOCUS       DBERCW010000010        49253 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.010, whole genome shotgun sequence.
ACCESSION   DBERCW010000010 DBERCW010000000
VERSION     DBERCW010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 49253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49253
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.010"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1946)
                     /locus_tag="ACL72M_000757"
     CDS             complement(<1..1946)
                     /locus_tag="ACL72M_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGS0715923.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLITFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRVN
                     DIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIALVGQ
                     SGSGKSTLSKILSGLYKIDTGKILFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILD
                     NITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARAL
                     INNPSIVILDEATSALDTINEERIT"
     gene            complement(1939..2487)
                     /locus_tag="ACL72M_000758"
     CDS             complement(1939..2487)
                     /locus_tag="ACL72M_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGS0715924.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIKNVLTNVEKIRELNLCHGSVGT
                     ISCLDAILKDEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVLLLELRGHDD"
     gene            complement(2568..2630)
                     /locus_tag="ACL72M_000759"
     CDS             complement(2568..2630)
                     /locus_tag="ACL72M_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGS0715925.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            2710..3564
                     /locus_tag="ACL72M_000760"
     CDS             2710..3564
                     /locus_tag="ACL72M_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS0715926.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKIEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGENKLKLHYTDH
                     FNKLVNKK"
     gene            complement(3609..5494)
                     /locus_tag="ACL72M_000761"
                     /pseudo
     CDS             complement(3609..5494)
                     /locus_tag="ACL72M_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775543.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(5517..5846)
                     /gene="mobC"
                     /locus_tag="ACL72M_000762"
     CDS             complement(5517..5846)
                     /gene="mobC"
                     /locus_tag="ACL72M_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGS0715927.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQV"
     gene            complement(5856..6215)
                     /locus_tag="ACL72M_000763"
     CDS             complement(5856..6215)
                     /locus_tag="ACL72M_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGS0715928.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            complement(7047..7424)
                     /locus_tag="ACL72M_000764"
     CDS             complement(7047..7424)
                     /locus_tag="ACL72M_000764"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715929.1"
                     /translation="MGQKVVAMLDFLLAYSDYSKDFRPLIIDQPEDNLDNRYIYRHLV
                     QQFRDVKAQRQIILATHNATIVTNSMTDQVVIMESDGVNGWIESQGYVSEKYIKNHII
                     NQLEGGKDSFKHKMSIYETALSE"
     gene            complement(7427..8203)
                     /locus_tag="ACL72M_000765"
     CDS             complement(7427..8203)
                     /locus_tag="ACL72M_000765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715930.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFWSLILTRKNFRNNLIFSIKKLVY"
     gene            complement(8231..8992)
                     /gene="pezT"
                     /locus_tag="ACL72M_000766"
     CDS             complement(8231..8992)
                     /gene="pezT"
                     /locus_tag="ACL72M_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGS0715931.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELFFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(8992..9468)
                     /gene="pezA"
                     /locus_tag="ACL72M_000767"
     CDS             complement(8992..9468)
                     /gene="pezA"
                     /locus_tag="ACL72M_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGS0715932.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(9913..10368)
                     /locus_tag="ACL72M_000768"
                     /pseudo
     CDS             complement(9913..10368)
                     /locus_tag="ACL72M_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10643..12382)
                     /locus_tag="ACL72M_000769"
     CDS             complement(10643..12382)
                     /locus_tag="ACL72M_000769"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HGS0715933.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESASNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEINSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELD
                     NQLVISPDGFMIF"
     gene            complement(12545..13429)
                     /locus_tag="ACL72M_000770"
     CDS             complement(12545..13429)
                     /locus_tag="ACL72M_000770"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS0715934.1"
                     /translation="MKKAMVIITPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEAIHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKLKED"
     gene            complement(13541..14395)
                     /locus_tag="ACL72M_000771"
     CDS             complement(13541..14395)
                     /locus_tag="ACL72M_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGS0715935.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(14453..15211)
                     /locus_tag="ACL72M_000772"
     CDS             complement(14453..15211)
                     /locus_tag="ACL72M_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS0715936.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(15273..15461)
                     /locus_tag="ACL72M_000773"
     CDS             complement(15273..15461)
                     /locus_tag="ACL72M_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGS0715937.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(15783..16349)
                     /locus_tag="ACL72M_000774"
     CDS             complement(15783..16349)
                     /locus_tag="ACL72M_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715938.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(16617..18296)
                     /locus_tag="ACL72M_000775"
                     /pseudo
     CDS             complement(16617..18296)
                     /locus_tag="ACL72M_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(18388..18549)
                     /locus_tag="ACL72M_000776"
     CDS             complement(18388..18549)
                     /locus_tag="ACL72M_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715939.1"
                     /translation="MNNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(19233..19532)
                     /locus_tag="ACL72M_000777"
                     /pseudo
     CDS             complement(19233..19532)
                     /locus_tag="ACL72M_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(19513..19902)
                     /locus_tag="ACL72M_000778"
     CDS             complement(19513..19902)
                     /locus_tag="ACL72M_000778"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0715940.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(19955..20139)
                     /locus_tag="ACL72M_000779"
                     /pseudo
     CDS             complement(19955..20139)
                     /locus_tag="ACL72M_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(20290..21084)
                     /locus_tag="ACL72M_000780"
     CDS             complement(20290..21084)
                     /locus_tag="ACL72M_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715941.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(21084..22091)
                     /locus_tag="ACL72M_000781"
     CDS             complement(21084..22091)
                     /locus_tag="ACL72M_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGS0715942.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(22091..23098)
                     /locus_tag="ACL72M_000782"
     CDS             complement(22091..23098)
                     /locus_tag="ACL72M_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGS0715943.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(23088..24113)
                     /locus_tag="ACL72M_000783"
     CDS             complement(23088..24113)
                     /locus_tag="ACL72M_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS0715944.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(24506..24724)
                     /locus_tag="ACL72M_000784"
     CDS             complement(24506..24724)
                     /locus_tag="ACL72M_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0715945.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(24970..25248)
                     /locus_tag="ACL72M_000785"
     CDS             complement(24970..25248)
                     /locus_tag="ACL72M_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715946.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(25462..27093)
                     /gene="rlmD"
                     /locus_tag="ACL72M_000786"
     CDS             complement(25462..27093)
                     /gene="rlmD"
                     /locus_tag="ACL72M_000786"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS0715947.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLDMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(27167..28141)
                     /locus_tag="ACL72M_000787"
     CDS             complement(27167..28141)
                     /locus_tag="ACL72M_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGS0715948.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(28215..28829)
                     /gene="pmp23"
                     /locus_tag="ACL72M_000788"
     CDS             complement(28215..28829)
                     /gene="pmp23"
                     /locus_tag="ACL72M_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGS0715949.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVQLNLYIIKCFTLFSTSG"
     gene            complement(28829..29803)
                     /locus_tag="ACL72M_000789"
     CDS             complement(28829..29803)
                     /locus_tag="ACL72M_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGS0715950.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(29811..31067)
                     /gene="glyA"
                     /locus_tag="ACL72M_000790"
     CDS             complement(29811..31067)
                     /gene="glyA"
                     /locus_tag="ACL72M_000790"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGS0715951.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            complement(31129..31560)
                     /locus_tag="ACL72M_000791"
     CDS             complement(31129..31560)
                     /locus_tag="ACL72M_000791"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0715952.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(31562..32164)
                     /locus_tag="ACL72M_000792"
     CDS             complement(31562..32164)
                     /locus_tag="ACL72M_000792"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGS0715953.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(32148..32987)
                     /gene="prmC"
                     /locus_tag="ACL72M_000793"
     CDS             complement(32148..32987)
                     /gene="prmC"
                     /locus_tag="ACL72M_000793"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGS0715954.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(32987..34066)
                     /gene="prfA"
                     /locus_tag="ACL72M_000794"
     CDS             complement(32987..34066)
                     /gene="prfA"
                     /locus_tag="ACL72M_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGS0715955.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(34063..34653)
                     /locus_tag="ACL72M_000795"
     CDS             complement(34063..34653)
                     /locus_tag="ACL72M_000795"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGS0715956.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            34776..34958
                     /locus_tag="ACL72M_000796"
     CDS             34776..34958
                     /locus_tag="ACL72M_000796"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGS0715957.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            35094..36467
                     /gene="mnmE"
                     /locus_tag="ACL72M_000797"
     CDS             35094..36467
                     /gene="mnmE"
                     /locus_tag="ACL72M_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGS0715958.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(36514..37449)
                     /gene="dapA"
                     /locus_tag="ACL72M_000798"
     CDS             complement(36514..37449)
                     /gene="dapA"
                     /locus_tag="ACL72M_000798"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGS0715959.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(37505..38581)
                     /locus_tag="ACL72M_000799"
     CDS             complement(37505..38581)
                     /locus_tag="ACL72M_000799"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGS0715960.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(39212..39284)
                     /locus_tag="ACL72M_000800"
     tRNA            complement(39212..39284)
                     /locus_tag="ACL72M_000800"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39249..39251),aa:Thr,seq:ggt)
     gene            complement(39384..39893)
                     /locus_tag="ACL72M_000801"
     CDS             complement(39384..39893)
                     /locus_tag="ACL72M_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGS0715961.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(39891..39987)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            40016..40447
                     /locus_tag="ACL72M_000802"
     CDS             40016..40447
                     /locus_tag="ACL72M_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGS0715962.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            40529..40906
                     /gene="mscL"
                     /locus_tag="ACL72M_000803"
     CDS             40529..40906
                     /gene="mscL"
                     /locus_tag="ACL72M_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGS0715963.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(40948..42042)
                     /gene="hemH"
                     /locus_tag="ACL72M_000804"
     CDS             complement(40948..42042)
                     /gene="hemH"
                     /locus_tag="ACL72M_000804"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGS0715964.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVAFVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            42197..43420
                     /gene="pepT"
                     /locus_tag="ACL72M_000805"
     CDS             42197..43420
                     /gene="pepT"
                     /locus_tag="ACL72M_000805"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGS0715965.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(43456..44109)
                     /locus_tag="ACL72M_000806"
                     /pseudo
     CDS             complement(43456..44109)
                     /locus_tag="ACL72M_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            44107..44271
                     /locus_tag="ACL72M_000807"
                     /pseudo
     CDS             44107..44271
                     /locus_tag="ACL72M_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(44542..45553)
                     /locus_tag="ACL72M_000808"
                     /pseudo
     CDS             complement(44542..45553)
                     /locus_tag="ACL72M_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1,RefSeq:WP_007521835.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(45779..48898)
                     /gene="phtE"
                     /locus_tag="ACL72M_000809"
     CDS             complement(45779..48898)
                     /gene="phtE"
                     /locus_tag="ACL72M_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGS0715966.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT        14682 a         9755 c         7858 g        16958 t
ORIGIN      
        1 gttattcttt cctcattaat agtgtctaat gcactagttg cttcatctaa aattacaata
       61 ctaggattat ttattaatgc acgtgccagt gctatccgtt gcctttgccc acctgaaata
      121 tttgacccca tctctgagat gatagtatta aatttcatcg gcatagccat gatttcatca
      181 tagatttgaa ctgctttaca aacttcctct atcttttgtg aagtaacttc gtgctttaaa
      241 gttatattat caagaatact tcggttcaat aaaaatgaat cctgtggaac tactcctaaa
      301 ttttgactta atattttttt atctatttga ttaatattta caccatcaaa taaaattttt
      361 cctgtatcaa tcttatataa tcctgatagt atttttgata acgtactttt tcctgacccc
      421 gattgaccga ctagtgcaat tctctgtcct ggctcaatag tcaaatttaa attttctatt
      481 acaggagctg agtctttgga ataagagaaa gataggtcct taatatctat tctaccttct
      541 aaagaacact ttttaagacc attttcaaca ttctcttcat tttcaagcca gatatcattt
      601 actctattta agtatcctgc tgccaaaata tactgcgtat aagcattaaa tattgagatt
      661 tctgaactaa ataaaattga tgccatggtt tgaaatgcga caacctcacc caataaaatt
      721 tttccattta aaacattatc aagtccaaaa atcaatataa ttataggagc gaacaattga
      781 aatacattag tagctgaatt gtataaaata tgcacaatac ttcgtttttt atactttgtc
      841 aatacgtttt ttaaatactt agaccagttt tcatatattt catcttctaa tcccgatatt
      901 tttattgaag aaatagtatt taatgcttct gtttctactg agtaaatcaa tgattgttct
      961 tgtaattctc tattaaccgt atcatacatt atttttctag tactaaacag aaacaaaaaa
     1021 ttgattaaac tcaatataag agctataatt gataatgttt ttgaactaag aaacatatat
     1081 attacaacac ttagaatagt cccgatatct actactcccc caacaacttg gttagtaaat
     1141 agctccctaa aaccactaag actagaaatt ctgtataaaa tatctccttt tgccctgagt
     1201 tcaaaaaaac tatatggtag tttaagcaaa tgcttaaatg taaaactttc aatatctcta
     1261 ctaaaaaata tattagaaaa tagaattccc atactcctag ccaagataga aataagatac
     1321 aaacaaagta gagaaaataa aattaaaaac gaggtttgaa aagaaaatgt attccctaat
     1381 gcagaattaa taaactttga agtcattact ggtacggaaa gtattattaa gtaacttatt
     1441 attgaaaata gtaacgtcaa aatcaatcga ccttttacct ttgaaaaact agagaatact
     1501 cttatccatg gagaaggaaa ctgcgacttc aaagattgat aattttcgtt aggaaatgat
     1561 agcagtacta tattactaaa atgttttgaa aactccttaa actcataatt tatatatcct
     1621 ttagaaggat ccattatata gaccttattc ttttttactt tgtaaataac tacataatgt
     1681 tgattatccc agaatgttat taatggtaac ggaagttcac taattttatt tacatcttta
     1741 acttgatatg agccagtatc aaaatttcgt ttattcaata actgtttcaa gtcacctata
     1801 ctataaccat ctctcccttt ttctatatca cgtcttaaat ctagtaatgt ctctttgctt
     1861 ttatagaaat gtagtatgga caagcagcaa cataaaccac attctatttg agacatttgc
     1921 tcaatattag gtacttttct agtcatcatg tcctcttaac tccagtaata aaacattaag
     1981 taatctatca tcttgttttc gagatatttc atagacaact ccagatactc ctagcataaa
     2041 agaaaatgta ttcatagtat tcaaatccgt acttaattct ggtttgatga cctgagaaac
     2101 gacattatca aaataaaaat ctatagattc ttttattaat aggttttctt catctttcaa
     2161 tattgcatca agacaactga tagtacctac agaaccgtga cataaattca attctcttat
     2221 tttttctaca ttagttaata catttttaat tattgataaa tcattattcc caatattagt
     2281 tttatcgaaa atttcttttc tagctaataa aatgcccgga gctccataac accaaaaatt
     2341 aggaaaggaa tcattatgat ttcttcttat gtctttccaa ttttttaata tattattgaa
     2401 acatttatct tctttatata gtaattcctc tatacatttt aatatatctg tactaggatt
     2461 aatttcataa taatatgata atgacattgc tactccagaa taaccgtgtg ctaaacctgt
     2521 tactgttata ttatctaatt gtgaaataca ataattaata cactttttta aatgatgata
     2581 atatccatca ccaaaaccaa aatcggtaaa aattttgaaa ttttcttcat acttggactt
     2641 cctttccgtt tttatttatt gtacaataaa taaaaacgga tttaattttt gttgggaaaa
     2701 tgggaaatta tgaaatcaaa acttggcatc acacttagaa aagttcgtaa aggaaaacaa
     2761 attagtctat gctctgtagc agatgaacat ctttcaaaat cacaaatatc tcgttttgaa
     2821 cgtggggagt cagagatatc ttgtattcga ctaatcaata ttttagacaa attacatatt
     2881 actttggatg agttccttgt tttacacaat gacgactata ccagttccga atcatttgct
     2941 aatctagtac agtacattcg taagcaatat tcatcacaaa gtatcaataa tatagcatgt
     3001 ctactttctg atacttctga ttacactcta aattcttttg agaaaacaat ggtaaaatct
     3061 attttacaca caatggattc gaacatcatt ccatcagatg aagagcttct tcatctgaca
     3121 gactatcttt tcaaaattga aaaatggggc tattatgaaa tcattttatt aggtaactgt
     3181 gtacgcacaa ttaactacaa ctcctacttc ttattaacta aagagatgtt aaataactat
     3241 atttactcat ctctgaataa aactaataag cagattgtct ctcagcttgc tattaattgc
     3301 ttcattctaa gcattgataa ggaagaattt tctaattgct cctatttaat tagtaagata
     3361 aagacattgt tggataatga actaaacttt tatgaacaaa cagtttttct ctatgcaact
     3421 ggttactttg aatttaaacg ttgccaatca accagtggaa ttgaaaaaat gaaacaagcc
     3481 atacaagtct tcgatatttt aggagaaaat aagttaaaat tacactatac tgaccatttt
     3541 aataaactag taaacaaaaa ataaatgaaa ttattctcta tcttttaact aattagtcgt
     3601 aaataatatt attctagtaa ggcattctcg tgaaatttta gaactgtaaa tttattggta
     3661 ttaataattt tcacaaacaa atccaatctt ctagctatct cctcatattt attaatttca
     3721 ttactaagtt cctgttgtaa ttttaaaata tatgtattga gtcgatctaa cattattgat
     3781 tccgtcatgt tcatttggtc aaaatcatac ttagctaatt ttctaccgat ctcatcttca
     3841 ctcttcaaat tgataaggac ttccgccatc ttgtttaagg tggcgatttt ttcttgggtt
     3901 tcttctagct tcatatcaat ctctgcaatt tctaatacaa gctcatcttt gatttcttgg
     3961 tattgtttgt tcgtgttaga tagttcaatc ataagattaa tttcagaaat cttctcttga
     4021 agacttttta aagttggtcg tctatagggg agtttttggc tatcgttgct caattgtctg
     4081 attaaggtcc tacccttgat gaaacaatta ttatccatgt tttctttatt atagacaaag
     4141 taagaagacg tttctcgaat gtagacttta tattttttat gattttcttc ttccataata
     4201 tccaattgat agttgggaat gaaaataaga ccgctctatt tgacaccgaa agacaccttg
     4261 atatagacgc ccttatcaac tagcttctct atttggttct ctgcaagttc cacttcaaat
     4321 tcacgaacgg tatctcattt ttccttaaat gtcttaaagg cttcttaaat gtcttaaagg
     4381 cttcctcaat ctcttcagtg gatactttat ccttatctcg ttcttcttgg aaagcatggt
     4441 actgttcctg taaattctct aatccttctg aagcaatgac ttccttattt ttaaaataat
     4501 cttgaaaaaa tttgacatca tataatttct tatcacttat tttttgatga cccaaactta
     4561 tcttttgatt attttctttc aggataaaag ttacattttt ttgttttaag tcaatggtta
     4621 gattcaattc ttttgctttt gttattaact cttctaaaga attgacacgg ttcaacaaaa
     4681 attctaaacg actttcaatc tcttgcttag caaaatgcgt tctaaaaaat tcttcatcat
     4741 atagatctcg tttgctgagt tggcgtcctc gaataggttt tgtcattgct cgatccgtca
     4801 tcatgaatcg actatgcttt tgactaaaat caatctgaac atgcaactgc tttgctttct
     4861 ctaaaaaatc atcaaactat ttagattgct gcatcaaaaa ataaagacgt tgtttcaatt
     4921 caaatttatg actagattcc ctatattttt tataacctcg ataagaataa cgtttctcaa
     4981 taatttttgc accagccatt ttagaaatac ggtctgaaat catacggagg tttcgttcca
     5041 aggcatagtt ccatatcaac tttttatctg aattgcggtc aatagcgttg attaggatgt
     5101 gattatgaac atgatctttg tctgtgtgag ttgctacgat aaacttaaaa cgacctcctg
     5161 tcaattccat catggtctca taaccaatgc ggttaatttc ttcaggtgtc agattatctt
     5221 caggagaaaa tgattggatg agatgatggg catgaatagt ttgttggtgt ttttcttgtc
     5281 ggtcatttct ggactcgtac aacttgtcgt tattagtaaa gttaacattg tacatttcta
     5341 ccatttctgt atggctagga aaatctaagt aattactcat gccaaaatca gatactaatt
     5401 ttagattatc tgttttatct ggattgagga tatatttaat caaacgccta cgatattttt
     5461 ttccgtgcgt cgcaaagtgt ttagtaacta ccatgaaact ccttcagtct tttcacctac
     5521 acttgaaatt ctttgtccac ttccttaatt aactctccga ctcctttact caattcttgt
     5581 aattggtcct gagaaatcag atggctttga ttaatcgcac gcgcaatttg attgatgtta
     5641 tttccaatac gtctcaattc aaaaactaac tggtcataag tatcagtgtt aatcgtgaca
     5701 aatgacatat tgggattaag caaaactttt ctggcataga ctgaaaaatt ttgacaattg
     5761 ctcttagcaa tccgttcatt caattggtgt aattctggat cagttagaaa tacttttttg
     5821 agattggtac gatagcgata aaccattaca tcctcctaac ccatatattt ttcacgaaac
     5881 tcacgactga gtggctgtac ttgattcact tctgcaatca attcttgaac gcaagtcaat
     5941 aagattgaga cgtgctcttg agtcacttga tgattttctc ttgcgacaac cagaacttca
     6001 tacacatctc gactaatctg ttcaaacttt tgagactgcc aaagggagaa ccaactttca
     6061 aaaattctat cctgataatt ctttttcaat aaattttgac gaagaaattc tgagaaacta
     6121 tccacttttt gttccctcat catttctttt atctgttttt cttcttgtct cgtgattcta
     6181 aattgcttac ggattaactt aatttcttgt cccatcttac cattctttca acattatact
     6241 tgtctgacaa tgtaaggctg cctcacattg tcagtacgat tcctaaagac ctcagtctct
     6301 ccttgttcgg tctttgcgag ctcagatatt gtgtccacaa tatcccaaaa atcatatcgc
     6361 cagcctatca aaacctacca gttttgacag ctaacgataa gataacttag tggctccgcc
     6421 cccaaacccc caggtaaaat tcttagttgg atttttaaaa gttgagaaaa gtatagcaga
     6481 agaaatttgg ggaagttatc acaaatcaag taaggactaa tctctaacac cactgcatgt
     6541 accgtcctat atttatgatc agctcccatc gtttacattt tcaggtcact gtcttttcat
     6601 accaggaatt agaattgaca aatttaatta gagaggtatt catttaattg ttcacttctt
     6661 cgctccattt ccattacaga aatttcttca atactatgtg ttcagctgac tcccatgatt
     6721 cgttgtacta cgtcctaaac gctcacggaa taagccgtac atctttccta gtttactctc
     6781 gtaatttacg tatataggtt acgacaccta tttggatttt agagttcctc atccgctata
     6841 tatggcttca agtcacgatt ctgtttgtag aaccttgatt tcgctaattc cttcctatcc
     6901 cccctacctc acgatattca ggcttaggag tcgctattgg tttcatctgc agcaaatatc
     6961 cacagaggac ttggacctca gatgtacact atgcctgtcg gacaaagaaa aaagtaggct
     7021 aaatttctaa cctacttttt ctgactctac tctgataaag ccgtctcata tatagacatt
     7081 ttatgcttga aggaatcttt tcctccctct aattgattga tgatatgatt ttttatatat
     7141 ttttcactaa catatccctg tgattcaatc catccgttaa ctccatctga ctccataata
     7201 acaacttgat ctgtcataga atttgttaca attgtagcat tatgtgttgc taaaataatt
     7261 tgacgttgag ctttcacatc tctaaactgc tgaactaaat gcctgtaaat ataacgattg
     7321 tctagattgt cttcaggctg atcaataatc aatggtctga agtctttaga ataatcacta
     7381 tatgctaata aaaaatcaag catggctaca actttttgtc ccaaacttaa tacaccaact
     7441 tctttataga gaatatcaag ttgttgcgaa aattctttcg agttaatatt aaactccaaa
     7501 atcgtgtatt ttctttagaa aaaatttttc gtttatatgc acctgataag tgagaacctt
     7561 ttttcaaaat gtcataacta ttgaaatgag caatatagtt aactattttt tgattattga
     7621 aatccttcat tatagtcagt gaatgttgat aacttccatc tttctcactt ataatatttt
     7681 cacttaacca ttgattaacc catgattctt gttcataatc atatatacat acaatatgca
     7741 atttatctgc tgcactaatt tctactccat gtaaaatatg aggatgtata tcataaatcg
     7801 gataattttt cattatgatt gagactgcca tttgtaactt tttaatacct ttggtagtat
     7861 tatgatcagt tactacaact atttctattc cattttttat gattgcctct gctaacataa
     7921 gaaaactaat atattctttt gaactagaaa aaacaacctt atcaaaatta ctaaaaaaaa
     7981 ttgtcttatc aacttttatt ttcttatttt caaaaaatat atcatatagt tcatcttcag
     8041 taatttttct atatttcgtt gcagtccaat tagaaaatag cttgtaatca taagaaacag
     8101 gtgtatgcaa atgaattaaa gtcttgtgaa agctaccgaa tttctctttg gaatttgtta
     8161 gttcttgata aacagacttt atcttgttat taaaccctct catttctatt ctcctaaaaa
     8221 tatcaattgt ttatttttca agtaattcat taagtctctt ttcccccacc tgcaacatct
     8281 ccttctctac ctgactccac tccccaaaga ataactcttg aagaacatct gctgctgaag
     8341 ttgtattttc ttttgaatca tatacacaac ttctatctcg ttggtaaatt tgaattcttt
     8401 caaagatagc tagttcttcc aattttcgtg tgttatcaac tagatgattt acaatgaaat
     8461 catgatgttc ttttggagtt gcgcgtgctt gatttggatt gataatgtac agttcttcat
     8521 aacggataag agtacttaga tacgacaatt caggctttgt cgcaattaag gccaattgta
     8581 cttcatatcc cttatttttc aagagttgtg ccgttttctt tggaacatca attgttcgta
     8641 aagttccctc gatcaaaaga ttgtatccca aactactcaa ttttgttact aaagactcta
     8701 ccatttttcc tgcaaaatct ttggtatatt ctacactgtc tttgccatat tcttgctgca
     8761 gttctaaata gtgtggatgc tgagaacgaa aactatcacc atctatgata acaatatttc
     8821 cttgaaattc tttctgttta atacgatgaa ttgtagtctt accggcacca ctttgacctc
     8881 caagcaaaat cgctataggt tgcttactgg acttttttcc tcttgtcagt gaacgaagat
     8941 tccttgctaa agcatgtttg aattcactat cagtataatc ttggatttcc attaagctac
     9001 catccgcttt tcagatatct ctaacatacg ttcaattcca tccaaatagc cactatatct
     9061 ctctatttca tcaaaagttt ctactaaata gatattcgta tgaatcaaat cagaaagatc
     9121 atcactcatt aaaatccaag gattagattc atcatcaatg ctaattccct gactatcttg
     9181 atagcgatag agtcgagata atagattagc acctctttct ttcacaattt caatttttaa
     9241 agtcaattca taatcttcaa caggattgag cattttatct tctcctacga tatcgacata
     9301 agatacatta aacttctgac aaatgatgtc tattaattcg gtagagactg aactcgttcc
     9361 attttcataa cgactcagac tatttcgtga aatacctaca atccgtgcaa attcgtgttg
     9421 tgttaagtca tgtgttttac gtaaggattt tatgttcttt ccaatcatgg caaactcctt
     9481 tatttttata attcaattat agcataaaaa agcataatgc accaaaaatg gtgcattatt
     9541 tcttgttttt ctatcctaaa ctttacttct ataaaagtca cctaaagagc cataaatatt
     9601 tattcttgta ttaatttttt cgatgcgcaa acgatatcta caaatacatc tataacgatt
     9661 caccttttag gatttttatt gtcaaaattg cctttatcta caaagacaaa atgcttataa
     9721 aatagtttga aatcaaggat tatcgccttt ttcgttgtag caacactcca catgtgatta
     9781 ttaggctatt agcaaagcgt atccaatacc tcaataaagt gttgttttta ctgatatttt
     9841 aactatattg tatagtctac tatttaaatc tcaattagga tattttatag aatacccaaa
     9901 attcaacaat aactaaaagt aagattccat tgtatttcct tgttggtctt tcatatcacg
     9961 aattttattt ttcagaatat taaagttaca aatttcatct ctaatatcgt tatccgctct
    10021 gtagccatta atcatctcag tcagagtttt ccctttacta ccattcttta tagtagtatt
    10081 tactcttttt atactgcttt caaaaggctc atatgtttta tacttaatta cttcgtcttt
    10141 aaaattaaat aaaggtgtat ccggcttagc attccataaa ataatcaacc acattatagc
    10201 attataaagc tgctttgcag tttcattcca cttttcaggt tataaatttc cactccctgt
    10261 attgtcatat tcttgtctat tatttacatg agaatcacct acaagcggat taaaaagagg
    10321 tagccctttg tgattaatta gttctaaaaa atcccttgcc gcacccatgc aacactgaat
    10381 aacttccttc ttgccatcaa ttttactctc agcgataaat acataatatt catcttcaat
    10441 agttgctact gcatcactat gtttttgttg atttgctaac agcttaatat gtactttagg
    10501 ctgaacttca aaatctctaa caattctttg tcttgtttca tgtcctctac aattcattta
    10561 agttctcctt tacaagttta gtaactagcc ttattatact atataaggta tgaaatgtac
    10621 cataatcttc atcaactagt ttttagaaaa tcataaatcc atctggagag atgacaagct
    10681 gattatccaa ttcttggcaa ttgcttgcta gtgctactgc ttctttctct aaaagataat
    10741 cttctgttga ttggttgaat attgctttga ggatccgtcc ttcgtatttc cattccagag
    10801 ctactagatc agagttgatt tcttgaaggc tatacttgcc atgcgaaatg attactgacg
    10861 cgtatttccg aatcttaatc agcctcttca taaagttcag catatcattg tcacttgata
    10921 cacgttccca aggcatacaa cgacgacaat ctggatctgg tcctccagtc aaggctagct
    10981 cggttccgta ataaatgcac ggtgttcctt tttgtaaaaa gagaaaggct aaggctgatt
    11041 taaccagttg aacatcttca ttggccgtcc acaggattcg ctctgtatca tgtgaatcca
    11101 agagattaaa catgacctct gaaatctgct gcttgtaata catagactct ccattgattt
    11161 catcgatgaa ctggtctgtc ttcttaattc ctcgtaagaa atagtccttg atactatcag
    11221 ataaaggata attcatgacg gcatggaact catctccatt tagccaaggc tgagatgtat
    11281 gccagacttc tcctaggata taaagatcag gatttttagc taaaactgcc ttacgaaaat
    11341 ccttccagaa ctgatggtca atctcattag ccacatccaa acgccaagca tcgatattaa
    11401 actcttcaat ccaataagtc gcaaccttta aaagataatt cttgacctct ggattggctg
    11461 tatttagctt aggcatatag tcctcgaaac caaaaacatg atagggtaag tctctcttat
    11521 taactagctt ttcagttgtc actgggaatt gttgaatatg gaaccaatcc ttataagcag
    11581 actgttcacc atttttgacg acatttttcc attgaagaga ttgcgaacca atatgattaa
    11641 ataccgcatc cagcatgact ttcatgccac gatgatgcgc ttgatccacc agttcccgaa
    11701 atgtctcctt gtctccaaaa tgacggtcaa tttcaaagta atctgtcgta ttgtacttgt
    11761 gattgcttgc agattcaaag atgggacaaa gatatagtcc agtaataccc aagtcttgca
    11821 agtaatccat atgatcaata atcccctgta aatcaccacc aaagaaatca tcgctcttag
    11881 gtgtgacaga tgaatcccag tctaaagtcc cttctgggtt taatagagca ttgccattgg
    11941 caaatctttc aggaaatatc tgataccata ccgtatttga aacccagtca ggaactttgc
    12001 aggcatcaat ctcatgaaga taaggcaact taaatccatt cccaattgca tgaagatttt
    12061 ctagagaatt ttccacacac cctttatcgc catacaaaat attttgacct tctgtatctc
    12121 tgagctcaaa gagatactgg atacgtgcaa agtcaactga cacttcaacc tgccaatggt
    12181 caaataaggt accagaagtt atcttgacca tttcttttgt atcctgataa aactcctcca
    12241 taaagataaa agggtcccca tagtgcaagt tgatgctttc aatgtcccct ttcttagttc
    12301 gaattcgaat atggagtttc ttatccttat aaagataggc atactccgac tcaggcctat
    12361 ggtaaatagc actcaattcc atcaatttgt ctcctaaagt attcattcaa attttacgca
    12421 aacgttttca aactcaataa atccagtata ctatttttgt aaactatttg caaggaatgt
    12481 ccgttgttaa aggaactatc ttttaaagta tacaaaaagc cttaaaaaag gctttctcta
    12541 tatactaatc ctctttcagt tttgaaaata cttctactcg ctgagctagg actttgattt
    12601 ctacaggtag gttatctgat ttatctccgt caacatctga ctccaattca ctatctgaag
    12661 agattttaat attacgcgct ttgatatact cgatattatc atttgcgaca acatcccctt
    12721 ttaataaatc aggaatgacg gataatttgg agaatataga ggcatctttc agaatcaaaa
    12781 tgttggcata gccgtccttg ttttcttcaa agattttctt atcagcgaag taatttgtca
    12841 aaaggaccaa aacatggata gcttcaccaa cataatttcc attttctgtc tcaaccttaa
    12901 tgttaaagac ctgatctgtc atgacagact tcatggtatt tacagcatag gttaaaatac
    12961 cgaattttgt tttgtcctct atttcaacat tgtgaatcgc ctcaggcaga gaaccgatac
    13021 taaagatata accaaaatag ttgtcatttg ctttaccgat atcaatctta ttggttaaat
    13081 caaaatccag ttcgtcaatt gcgccatcga tgtcttgatt gatttccaaa agttttgtaa
    13141 tgaggttacc cgtaccgcct gggataatcc ctaacttagg aatgtagtct ctctcatcaa
    13201 tacctgaaat gacttcattg acagttccat ctccaccaaa cacaaccact gcatcatact
    13261 gctcacgaga agcttcttca gcaaaatgtg ttgcatccag cgctttttcg gtaattttgg
    13321 tttcaacata ttcaaagtat tcttttgctt tattctccag cttttctttg taatccaaag
    13381 ccttctcgcc accagaagta ggggtgataa ttaccattgc ttttttcatt gattttatcc
    13441 ttaattttaa acagaaatgt ttacatttcg tcgtatgcaa gtaaatgtaa tcctattata
    13501 caatgaaaat acagaaaaga gaaatctgac gtactggaga ttaatacgct tttattctat
    13561 tttcccatcg cctaactaca tcctttaagg gttcatccaa gtaagaatag gccttatcct
    13621 tgatccaatc aggaataccg taagctgcct ctgctatgct acaagtgatt gctgcgagag
    13681 tatcactgtc gccaccaagt gagatggcat ttcttatcgc atcttcgaag tctctacttt
    13741 caagaaaggc gataatggct tgagggacag tttcctgaca tgtttcgtta aaacgatagt
    13801 taggacggat ttcatctaaa gtttgagata gattgtaatc gtattctttt tctatataat
    13861 ccttaattcg tcttttacac tctgtaggat tgtcgttaat tgattgctcg tactctctac
    13921 aataaccacc aaagtaaaaa cgacatagaa agatagcatc agctgtagcc atagcgcctt
    13981 tgacaccttc tggatgatta tgagttacct ctgcagaaag actcgtaagt cctctagatg
    14041 atggccatat accagttttc gcataaaaac cacagtccat gatccaagca catggagaaa
    14101 tacgcatagc tgatccattc ccaaagctat tataaggctc acggttatcg ctgtttagcc
    14161 atgcattaaa ccgagcaccg taatcagcat tcggatacat tctgccatat ttcttcatcg
    14221 cgtcaatgaa gtcatctttt tgtccaccat tcataattgc ttctgcaaca gcacaggtca
    14281 taaccgtgtc atctgtaaaa aagcagtcct tccgaaataa aggaaagtcc tttgttttga
    14341 tattgttcca ttcgtaaaca gaaccgacaa tatctccaat aattgctcca agcatcagat
    14401 tcctccttgt tcattttgat gctttttata ttggttatct accatattta ttttagaaaa
    14461 taacatcctg ttggatttta aaaatttcat ttttttcaaa atagggtttt accatttctt
    14521 tccacctagc tctatgaaaa ttgattgatt ttaaaggaga taggccataa tttcccaatg
    14581 cataaccatc atttacttca acaacaagtg ttctgccatc gcgagtaaca ccgatatcta
    14641 gtccataagc tattggcgca tctttccaac atgatatcgc ttcatcaatt acacttgcat
    14701 caaattgtgc atgataatca cctgtatagg gtcgaacatc taatacgcga ccatctaaca
    14761 caaaacaacg ccattcagct atgaattcta caacctcact aatccatata ggatagtcga
    14821 aaggtagacc aatacctatt aaatcatggg ttccattaac aactcttcca gtaaagactt
    14881 ttgaaccagc tttaggctta ataaattttc cccaattatc aggtatattc acaatctctc
    14941 ctaaaatacc agcataaatc tttcgaccat aaaactcttt aagctcaata ggatagtcat
    15001 gaaccggaac gtttaagccc atcattttta gtaatgctct agtctccatt atataatcta
    15061 caactatatc ttcacttgtt aactctttta tttcagaaaa agattgatat aaaataactt
    15121 cttctccttg taagtaggca cctacttgag cattgtattt attaattgaa acctcacttg
    15181 gtaatttact ttgtctaata taaacaacca tttcatcact cctatatcac tagtgttaca
    15241 ccaatttgta aaaaataata gcaattttgc tcttattttt ttgagtaaat agcccccata
    15301 atatcatcga aataatcaac ggtatttagg agtaattcaa taacctggga ctttgttagt
    15361 cgcattcccc ttctatctct agcatcttct actaaatttt caagtttctc tagattttta
    15421 tcatccaagc taatcattat tctattttta tcggttgcca ttttcatcac ctcaagttaa
    15481 ttctatcaca ggtgtaacac tagtgtcaac tggcttttat aatacattag tttaaaagtg
    15541 gagaggattt ttaacacagt aactttaaat ctttggtatt aaaaaatttt cacaatattt
    15601 atagaaataa aatctgtctc aaatcagtta tcaaatctag tataaattat gagcggctac
    15661 tctaatactt tccctctaaa caagaaaaag acttacactc aagggttttc ttccccccct
    15721 tcgttataac gttttgactc ttttactagc aaaggtatat actcacaagg aactttggtt
    15781 gactattgaa tctctccaac ttcttcttta acatatcctt ctacatcttc aatctctaca
    15841 aacattgggt ctaagtgaca caagaaatgc caaacttcga tccctttttt tctgtaaaga
    15901 atcgcttcac cgtcttcact tccgaaaaag cttctgtcga tttcatatcc gcggctttct
    15961 aagaagtctt ttgctttacg atagttcgtt tctcttgttt cgacataggc tttaacttca
    16021 tggttgttaa cgacatatgc atcaattttt gaatatcctt cgatcactct atcatttttg
    16081 agggataaat ttgaaatctc tttccaaata atgtttacat tttcctcagg atcgaacata
    16141 aatttagata aaggaacaat atttccgtta aaaataattt ccatataatc cggtatgttt
    16201 ttaggattaa aatactccac ttcaaaacca tcttctgttt ccagagtgta tcccgggatt
    16261 tgagctacaa aggctttccc atcttctatg gaatcaaatg ctactaaatc tttagaataa
    16321 tcattttggt acaattccaa tataaccatc gataatctct ccattttcat tatcaggcta
    16381 atgtaaataa gcacgtcacc tgaccaattc aggctctctg tatcatctca tcatatttcc
    16441 tacttacttt acgagtctta tacccagaac acaccttatc gaccttcggt ctcacctcgt
    16501 cgcattggct gaacatctac ttttactttg ctgatgcttc aactcgtaca agcagtgata
    16561 ccgcctcagc gtgatgcgtc agtgggactc aaaaggttcg gggaaccttt tgaggattaa
    16621 ctacgtttct ctaataaact tacacattca acttgttcat cattgtccaa acctatgttg
    16681 agattttctt ctataattgg tagcttaaaa gtaatggatt ttagccattg tccgttagat
    16741 tgtttttctt cataaacttg aatttcagaa atcaaagctg aaattaactg cctacgctct
    16801 acatcattca tgactttata gagcttatca aaatagatca gaaccttata tatgttatct
    16861 cctgtaagct tttcagcttc aatagtctgt ttctttgctt tcgcatcaat tagtgatgat
    16921 tctaattcat ctagtttgtc atacatacga tatagtctat catctaaatc ctgtttcctt
    16981 ctcttataat gcttatcttc aacatctaaa ttatctattt cctcaattag cttaaacttt
    17041 gtagaatgac tctttctcaa ttccttttgg taattatcta tttctctttc tatttcagag
    17101 gtatccacct tcatgttgat tttttcttgc atcatagaag caaatttcgg attacttact
    17161 atcttgacaa tcacctctgc aacagcatca tctaacaatt cttctctaat ttgcttactg
    17221 aatgtacact tatgacctct tatcatctgc ctatgtttac aaccatagta ataaaaatct
    17281 ttatactttg tgccatcttt ctttttcttg atacacttgt tcccaaacat tcccactcca
    17341 catatcgggc attttacaat tccagaaagc aagtgtgtgc gtgtatcttt tcctttattc
    17401 acatgctcat atttctttgc ttgagatttt agcttaacct gagcagctta ccaaacttca
    17461 tcggaaacta tagcttcatg tatcccttca gatattagat attcatcttg ttcaacctgc
    17521 ttatattcat ttcttgtacc atgaactttt tctaaagttc ttcttccaaa tgctattttc
    17581 ccattatata caggattctt taatatcttt cttataagac ctgcatcaaa caaaggattc
    17641 ttaccattct gtcttgggat ttttctaatt ccatgattct ctaagtattt agatatccca
    17701 ttggctccta tcgtagtatt tacatactgg tcgaaaatcg ttcttattgc aactgcctct
    17761 tcctcattta taaacagctt gccgtcttca agtttatatc catacggagc aaagccacca
    17821 ttccattttc cttcccttgc tttttgaatg caaccttcca ttgtttgaat acggatgttt
    17881 tctctttcta tttcagccac agctgataaa acagaaatca ttagtttccc agcatcttta
    17941 gatgaatcaa tgccatcttc aacgcagata agattaactc cataatcctg cattatctga
    18001 agtgtagaaa gaacatcagc ggcatttctt gcaaatcttg ataacttaaa cacaagaaca
    18061 aaagatactc catcttttcc agattttata tcttccatca ttcgattgaa ctgtattcta
    18121 ccttcaatag acttgccaga cttcccggca tcttcatact ctccaacaat ttcataatcg
    18181 ttgtaaatag caaaagcttt cattcgtgat ttttgtgccc ctaacgaata cccctctatc
    18241 tgtattgacg tagatactcg tgtatagagg tatactttta ttttttcttt tgacatagta
    18301 ttaacctcaa tataattttt ctatatcata tataattttt ttaatttaag tttggactat
    18361 catttcaagt atattataac acttttatta gtccgtctca atttgtgttt ttgccatgtc
    18421 aaaactattt ttcatctctt gattttttgc tggcgttgga tcgggtagat tatctaaatc
    18481 taaagcacca gcatattttg caatcagatt tgctattaaa tcagccaatc cattccagtc
    18541 attgttcaat atatacctcc tctaaagttt tatatctaat aattatttgt ttaattaagt
    18601 tttttgacat tgacaagtgc tttggattag caacatagga atctcacctc cgcctctatt
    18661 ccggatgagc cggcttcaac cttagaagta tcattatcct cattttcttc atagcggata
    18721 gggtatccct ccctatattc aaactcttac ttatcgctca ctttcttttt gtttagcaga
    18781 actttttttg ccgaattatt cagccgaaag atcttgacgg ataggttatt acgctccaaa
    18841 aataattaac gtcttgtctt ggtctattca attgttaagg ttcaaaattt atcgaaagtt
    18901 attaatcttt ttaaaatttg accatcagaa aatatttatc ttgatgtaac aaaattctat
    18961 aaattaccct cttatactta acagtgaaaa gaagtctttc ttggtaacca attttgaaat
    19021 agaatttgct tatataaaaa ggtccaattc ccactgcata agtagcagtg aaaattagac
    19081 cctcttggta actgtcatct aaaagtcttc tagcatttct ttaattttct aatcgccttt
    19141 aaagtgtcat atttatattt ttttatctct ggcatacttt gatacctttt tagacttaaa
    19201 gtctttaata gtgcctttcc acctcttttt atctataaag attctcctac atcataattc
    19261 atttttttat ttaaaccttt ctgtcttagt ttgtctttat cttcttcata ccattttaag
    19321 attgtcacat agtggttttg ataggtctta ccactgcttt ccatgtatct ggatagttta
    19381 tttatcatta tatctgtgtg tgagtttaat ttttctttta gatttttata ttcttctttg
    19441 cttaacctta catttttgaa ttctccataa aaaatggggg tggacttttt atctatctct
    19501 ccctctctct ctttatctat ctctatatct ttccatgtaa ttccaatctg gagtacctct
    19561 actgtctatc ggtaatttaa ttttgatatc tggcaatact gtgctagata tttgatcttt
    19621 atattcagta ttttttaaag cttgcctaat aattgaagtt aaatagaatg ctacttcttt
    19681 attcaattct ttatttttta attttaaaca atgaattttc atatctaggc ttgctttata
    19741 tttatgataa aagactgctc ctaaaaatga aacagatata aaattttcaa aaactctata
    19801 atttttatca tctatatctt cgtagtaacc taagatacca ttgtcaatat ttgtagcact
    19861 aattctagga gtttttccat cgagtaaata tctttttgga atagatgagc ctgttggtac
    19921 ttaactcgat ttcccctttt tttcggtaat aaatatttct ttttattttg ttgtctgata
    19981 tttttcctac ctgtcctttg taggatgagt attttctaga ttttcttgaa taacttttta
    20041 cttgaagttt tagcttttga actagtcgtt gtactttctt tttgtttatt atcagtcctg
    20101 atctttttaa tattgctgtt attctctata tcctattttt cattcatgat attcttttac
    20161 taattttatc ttaaattctg tgctgtattt gccattaaaa aactgacctc ctttagttag
    20221 ttttttggcc taacttttga gggtcagttc aaaatttgcg acttttaaat gaattccaat
    20281 attcaattat taagagttaa catggtgctt gccaatagga atcattagag gcgaattgga
    20341 aatagggtca cgtataattt ttgcttcaag attaaagata tctttaacta gtttatcatt
    20401 tagtatatct tcaggctttc cctctgcaac aagtttacct tctttaattg caaataggta
    20461 atcagcgtat cttgctgtta gatttatatc gtgcaaaatc atgcaaatgg ttgtcttata
    20521 tttttggttt agatcagtca agaggtctaa tagttctatt tgatatgaga tatccaagta
    20581 agtagttggc tcatctaaaa gtaggatact tgtatcttgg gctagggcta gagctatcca
    20641 tactctttgc ctttgacccc cagaaagttc ttcaactagg ttatttgcta gatcttcaac
    20701 attggcctta accattgatc tgtttattat ttcaaggtca tcttttccaa gactcttaaa
    20761 aggctttctg taggggaaac gaccacggct tacaagatca gctactgtta ttgattcagg
    20821 gattattgga gattgaggta atatagctat gtgttttgct aaatcttttt ctttataaga
    20881 attaattgat ttattatcaa gcaatacttc tccctctaat ggctttataa gtcgagacaa
    20941 ggttttaatg agtgttgatt tcccacaacc atttgaccca ataataactg atattttttc
    21001 ttcaggtatt tttatattta tattttccaa gattattttt tcatcataac cgcaggtaag
    21061 attatttgac cacagacctt tcattatata ttcctcctgt tcatttttat tagtaagtat
    21121 attaagtatg gtgaacctaa caagccagtt acaacaccta ctggatatct agctggtaaa
    21181 atattttgag agaatatgtc tgataacaaa actagtaaaa ttccaaccaa tccagctaat
    21241 attgggcttc ttttcttgcc aatatttaag gctatgggac cagctaaaaa agatatacaa
    21301 gctattggtc ctgtaattga agtagaaaaa gcagttaaag atacagcgca aaaaattaaa
    21361 acaagccttg aaagctcggg atttgctcca agtccgattg ctatttcttc accaagttca
    21421 ataatttcta gtcttttatt aaaaaataaa actaatatag tagcaataat acttactatt
    21481 agaacaagag gtatgtcatc taactttgta aaagataaag agccactgag ccatctcata
    21541 acttcttgta attcatatct tgctactttc aacaataaaa atgaggtgcc tgctcttgtg
    21601 acagcttgaa aaccaatacc taatattatc agtcttgctg ctgaaaaacc atctttttta
    21661 gctagtaaaa ataatattaa agatgatgtt agtccacaag ttattgaaat aattccagta
    21721 gttaaactat ttgtttttaa taccaatatg caaaagaccg ctgcaataga tgaagaactt
    21781 gtgacaccga ttatatcagg acttgcaaga ggatttctta acatagtttg aaagataaat
    21841 cctgccaatc caaaagacca gccagctata attcctgcta ataattttgg taatctaatt
    21901 tccataatcg aaaaactagc tccaggaaca gtttcactat ttaagacttt aatcaaagtt
    21961 gaaaaagaat aactttcatc tccgataagt aaaatgaaaa atgatagact gattattatt
    22021 aataaaaata gtgaggaaaa tagtgttatt ctattttttc ttttttgaat acctataatt
    22081 aaattttgca ttagttatta acccctctat ttttcatagt tacataaata agtactggac
    22141 ccccgattat tgcagtaatt atccctactt caatttcacc tggtttacct aacatacggc
    22201 cgattatatc acatataagc aagagctctg cacctataaa agatgaagaa atggtcattg
    22261 tgcgtatatc tttgcttata aataagccac aaaagtgagg aactataaga cctacgaagc
    22321 caataggtcc accaattgca gtaatacttg aacataaaag cacacttgca attattgcaa
    22381 gtgatcttat cctattaaca ttaactccaa gaccaacagc catttcatca cccatagcta
    22441 aagcgtttaa atctgatgaa ataaatatag ctatcaagtg acctaaaatt ataaaaggta
    22501 gtagtgtaga tatagaagat aatgtagctg ctccaaggct acctatttgc caaaatctaa
    22561 atttgtctaa gacgttatta ttcggtaaaa ttaaaaaact tacaaaactg cttaaagcca
    22621 tactaacaca agttcctgat aaggcaagtt ttataggggt aaggcctgct tttccgctta
    22681 cagcaatcgc gtatacaaaa attgcactta ctaagccacc aatgattgca aaacttatat
    22741 ggcttatgct tgatgaaatt cctaaaaaag aaagaccaat tactacacta agacttgctc
    22801 ctgtgtttat accgagtata cctggatcag ctattgggtt tctagtaact gattgcatca
    22861 atacaccgct tatggcaaga ctagaacctg ctaaaattgc aaaaatagtt ctaggtattc
    22921 ttttatatat aattgattta ataaaatcat catttgtatt gcccattcca aaagctgcta
    22981 aaaaatctct gatattaatt tcttttgttc caagctttaa tgacaaaaat attgtaataa
    23041 gaagacctag gcagattaca aaaattatgc ctaggtttat ttgtttttta tttcgcattt
    23101 ttgcatgcat ttcctaaaag atttaggtat tcttcaatag tatagtttat tgaaagtggt
    23161 gttggagtgc atgaggctgc taacggtgta ttatctggaa ttacagcaac ggcaccattt
    23221 ttaattgcat ttattttacc taaaagagga tctttttgta aagcttcaag agttttatca
    23281 tcaccataag ttatgattac atcagcatca tttatcttat ttgcttcttc tgcagaaatt
    23341 tcctttgcaa aactatcttc actctcaaat tcttttaatg attcagggaa aactagacct
    23401 aaatctgtta aataatttgc tcttggatct ttgctagtat aaatccagaa ttttgatgta
    23461 tctgcagcat taatcatagt aaataatact ttttttcctt tgatttttcc tttgatttct
    23521 ggatgttttt ctaattcttt ggatatacga gcttcagtat ttttgattaa ctcatcacct
    23581 tctttttcca tacctaaggc ttttgaatca attttaatca tatctctcca taaagtttgc
    23641 caaggtttag atttgtatgc tgctacagga gcaatttttg atagagtgtc ataatcttct
    23701 ttagttatac cagaataacc tgctaagata acatctggtt tagaatttga tattgcttca
    23761 aagttaagtc catccaaatc gtcaaatagg ttagctttac catttagttc tttgattttt
    23821 tcttctgtcc atggtaaaac tcctttatca gcacttacac cgtaatttgc ttttgaaaat
    23881 ccaacaggaa ctattcctaa agctaatgct acatcatgat ttccccaagc aatagttgca
    23941 actctttcag gttttttatc taatatagtt tgaccgaaag catgatctaa aactatttta
    24001 tcaggcgcat gctctttaga agtattttct tcatttttaa cagaattaga agaacaagcg
    24061 ctaaaaacta tacacatagc taaaatagct attagaaaaa atttgttttt cataaaaact
    24121 ccttaaacat atttcaagtc tattgtatcg ataataatta tcattgtcaa tagatacagt
    24181 tacaaattta ataatataat tttttcaaaa aaggatctag tttttatttt tagttaaatt
    24241 atgtctatat ttttcattaa ctcatcaata aaaatttgtt tgctaatatc tctttcttct
    24301 gattttgttt caaggattat tgctacatca ttcatatttt taggtaaata ccaaccatct
    24361 ggcttatctg aatatccctt gaagcctaat tgattaaaag tagttatttg accagtacct
    24421 tgattgatgt tttcttcaac ttcattaaag cctatacttc tcttgcataa tccctaactt
    24481 gatcttctgt ccttaaagtc attttctatt cctcgtcact aaaattatct tcaaaactaa
    24541 taatatcatt aggagtgcaa gataaagcct tacatattct ttctaaattc ttaaatgtaa
    24601 ttggtttatc ctttcccatt tgtgccataa catttgttgt aagtcctgcc atagctatta
    24661 catctgtttt ctttagtcct ttttttgcta actgtatcca taatggttta tagttaagtg
    24721 ccataatatc cctctttttt tcttcattag atttatttaa ttatagcata aatattgatt
    24781 tcattcaatc ttacattgat ttagtgattt gttttagaga atttgttgtg ttattccgtc
    24841 cttattttgc cataaattgt tttaagtggg acctcttatc cttaccattt ttacctccta
    24901 attttgagta taaaaaagac gatagagttt ttaatttcta tcgtctgaga tttacatatt
    24961 aaattttcat cacaaaataa gactctttaa agaatcttta aattcattgg tatgctgctt
    25021 acaatatcca ttattaaaat ggatattgta agcagcacac caactattta ttttttgagt
    25081 tttaaacttt ggtagaagtc ttgaactcct tatatttaca taactatttg cctctataac
    25141 tgttatgaca cgaaaccaac aagcaagttc aagcacctcc atatctttat tcaaatgagg
    25201 actaagatat tcacaaactt tatcataaac ctctttatct tttttcataa aaggggcata
    25261 caacttagca aatttatcct aaaatttttt gttgccttta tcaatcattt caacgctcct
    25321 ttaaatataa aaatgatcct atcaatcttt atattgagcc tattttctaa ttgatacctt
    25381 gcaagaaagg aataatagct gttcctatac caagtaggaa tgtaataaat gcagaaagtc
    25441 atatactgtc attcttttct attaaatcat tttgaagtgt ctcaaagcat ccatgatggc
    25501 ttcttctttt tcaggtgtac actgtggaat aatttgttta tcctttttag acttgttgta
    25561 atgttctcgt aattctattc cacatttctt ttttatctgt gcaatatata atgtcgaaac
    25621 ttttaattca aatttattcc aaacatattc tttgatttga gcatatgttg ctttgctctc
    25681 cgcacttgtc aaatccatct catccagctc aatttcaaca cttatgtgct tatcgacatc
    25741 gagtttggac aaaagtgcta ccgtctcgac gtgatgcgtt tgaggaaata gatccaccgg
    25801 ctggactttc ttcaattcat atcccaactc ttggtatagt ttaatatcac gcgccatggt
    25861 tgcgacattg caggagatat aggcgatgcg atcggctcct gtttgggcgc ttgctttgat
    25921 aaagctttct gtcaagccct tgcgtggagg atcaaccaag ataacggttg gttgaatacc
    25981 ttccttgagc catttcttca tggcattttc agccgtgtca cagacatagt gggcattagt
    26041 aatcttgttc aaagaagcat tcttctggct attctctact gcttctggaa tcagttcaac
    26101 accgtagact tctttgacat gcttggcgac tgataaacca atggttccaa taccagaata
    26161 ggcatcaata atcacatcat ctttttttaa ctctgcaaag tcaatggctg tttgatagag
    26221 tttctccgcc atttcagtat tgacttggta aaaggctggg ccagcgattt ggaagtcatt
    26281 tcccaacatc tggtccgtaa tatagtcttg accataaaga gtgcgccact ccttaccaaa
    26341 aatcgcattg gtattctggt cgttgatatt ttgcatgaca gacacaatct ctgggaactg
    26401 cttgataact tgttcaatca attggtcaac acgaaaaact tttggacgag ttgtcaccaa
    26461 aacgaccatg atttgtcctg aatagtgacc acgacgcacc acaagattcc gaatcaatcc
    26521 agattgttcc ttttcgtcat aaggttttaa atcaaaacga cggagcaggt ctcgaagagc
    26581 tactacgact tggtcaatga caggatcctg gataaagaaa tcttcaaggg gcatgaggtt
    26641 atgcgaattc ttacggaaaa atcctgtttc caagacacca ttcactcgac gaacgggcac
    26701 ctgcgcctta ttgcgatact tgactggatg ttccatatca agcgtttcag caacttctac
    26761 atctgcaatt ccagcaatct tgtagagact gtccttgact tgcttggttt taaacttgag
    26821 ctgttctgga taagaaaggt gtcctaaatc cgcgattcct gaacgcaggt aagccaaatc
    26881 tagatcttga ttacggtgtg gtgactggac aaggtatttt tcaacttttc caaagccaat
    26941 ctttttattg accttgagga cacgcatgag aattttttca ctcggtaaag cattctctac
    27001 aaaaaagacc aaaccatcta ccttggcaac tcctgcccct tcatgggtca aatcaacaat
    27061 ttcaacttct acaatatcat ttttctttaa cattcttttc tctttctatt ggccgacaaa
    27121 aaagacggca acgttacggt taccatccat tataccatga aatttcttaa gaaccaaaac
    27181 tcttgaagaa gttgacaagg gcttgccaga gggagcttaa gaagttacca ccgtcctcta
    27241 gcgccttatc cgcatcaaag ttaaggttga tatttttaaa actgtcgcca gcttgtgata
    27301 cgatgctttg tttaaggtca tttagggttt tagtgaaatc tgcattgctg aggatatcac
    27361 tctttgagag attcaaggca aaattgatga tgatattgat ctggtttcct gttatgacct
    27421 gatcaagttt gtaatttttt aaggtatctt caacaatctt gcgtacatct tcttctgtca
    27481 gatttccctt gctttcttta gctttggcga gtcctgactt gatatcagct agggcaacgt
    27541 ttaatttatt agcatcatag cctgatttgt ccttgttttc agcattgata tctgacaaag
    27601 cctttagctc ttcttgagcc aaatctttat tggcttgcgg caccttggct ccattagctt
    27661 ctagcgaata gtagatccca gccaaagcac tctcacctgt aactggaata ggggctgcta
    27721 cagtgatttt ggcatgttcc atacccagcg ttactgctgc gtttcggtac atatcctgag
    27781 tcaccttagt gatattttct ggtgtttcaa tcttgacctc aagtggcgat ttgtcaccta
    27841 gcttttgaat cttggctgat gaatacaact gtaagctaga gtcattggcc acattcatga
    27901 ttttagaata aacatcaggt gtcatggtct tgagttcttt ggtatctgtt gaggcattgt
    27961 agcccagttt tttaagagtt tgattttttt ggtcttcaga tagggaggaa cctaggacat
    28021 attcaggttg gacataggtt tcatcgataa ctttttgaac atctgttgct gcatggacgc
    28081 tattcatagc tgttactgcc cacaagaccg cagcactagt cagaaagagt ttctttctca
    28141 tagggaattt cctcctttac ctttctagag taatatatct atcttaaaga aaacttataa
    28201 caaaaacacc tgaactagcc agatgttgaa aagagagtga aacatttgat gatgtaaagg
    28261 ttgagttgca cctgtctaga ataataatag tttcctccat ttacatagag ttcggcaccg
    28321 tgaaaaatgg aaatgggatg aatataacta taagtctttc cagtcgtatt accaagcaag
    28381 ggggcaacag tctcacgaga gtactgtttg gctagagcca aggtattttc cttgccattt
    28441 tgggcgataa aatcgatata ggcaggtcca aaattatagg cttgaacagc tgtccagata
    28501 tctacaccct tcttctgcgc cagatagaga ttgcctgtca gagtttgaat gccttgccga
    28561 atgctagagg cattatcatt gatggtgttg gtggaaccac ttgcagactc actagactgc
    28621 ataacatcgc cttcttttcc ttttgtttca gtataaatca tagcaagcac aagctcttcg
    28681 tttgctgggg tgtctttttc actcaatatt tctcgcacca tgggttgata ggtcatgact
    28741 tgtttgacat cttgatgaac gcggtaagct ttatagccag caaaaaggaa gactgctagt
    28801 acaagcactc ttcgaattcg tttaaacatt atttactttg gatatcctcg atatttttga
    28861 ttaagataga gtaggttcca ttttcgtttt ggataaactc aacagactcg gcgtcttgat
    28921 agacgttatt gggaacgatg agctcaattc catttgataa ggagagtttt tggttttcaa
    28981 atttctttaa ttggcgactg acatcaattt catcaaattg aacaggttct ggtacggctt
    29041 ctttgacttg gtcaataaag ctcaaacgag ccgtcagatt gttgtcaaaa aggtcattag
    29101 ccaatttctc aggtgacaat tcattgcttt cttctaggtt gttgaaaata gctgatttga
    29161 ccttggattg aaattgaaaa tcatctgtgt taaaagattc agcaattctc tgggctgttt
    29221 tttccagttc cttgatagat tttttaggag aaatcttagg agcgacagca agaagattat
    29281 ctgaaaaata gttcaaaaaa gtcccgttgt acttgattcg tttttcaatc aggtgatact
    29341 tgctactctg aagattgacc accaaggcct catcagctcc tgttccaaat ccaggcaggt
    29401 tattctgagt tagcttgatt ggattatcaa cttctcctcc gaggtgggtc aaggtctccc
    29461 gcagggcaat tcgcaagaaa gcgaaatgtt ctacaccttc tttagaaaat tgaacaaaaa
    29521 tcaagtcatt ggtcttgaga ttttcagaaa tgctaaactc ctctttccag agattagcca
    29581 gcgttactga tgtctccaac aaatcgtctg taatatgatt gaagaaggga ttttcttctt
    29641 cgaaaatccc agtcttggct tcatctgaat acacatgttc aattttttta cgcaggtatt
    29701 cttcgatttt tggagtaata ttgagaaact tatctgctaa gaacagttcg gtatcatccg
    29761 gactgaactg gtgaataatg gctttcttaa tataaatgtc cataaaagtt ttagtcctcg
    29821 tatagtagga aggcatctgt caattctttg actgcacttc tcacttcttc taatacagcc
    29881 tcattttctg aattcttaag ggttttaatg atgagttcag ccactttgcg actttcttct
    29941 tcaccaaatc cacgtgcagt aatggctgct gctccgatac gaatcccact tgtcttgaat
    30001 ggtgacaagc tttcgtaagg gattgagttt ttatttaagg taatattgac ttcatccaac
    30061 aagttttgag caactttgcc gttttctaca actttagtca catcaacaag gaagagatgg
    30121 ttttcagttc cacctgaaat aatacggaaa tcagggtctt gcaagaagac atctgccata
    30181 gccttgctgt tcttaattac attggcagca tattccttga aggctggatc caaaacttct
    30241 ttgaaggaaa ctgccttagc cgccacaaca tgctctaaag gaccgccctg aatacctggg
    30301 aaaatagctg aattgatttt tttagcaagt tcttcgtcat tggtcaaaat caaaccacca
    30361 cgaggtccac gaagggtttt gtgggtcgtt gttgttgtga tatgagcgta tggaactggg
    30421 cttggatgaa ggccagccgc aaccaaacca gcgatatggg ccatgtccac catgagcttc
    30481 gcaccgacag catctgcgat ttcacggaat tttgaaaaat cgataatttg agaatatgct
    30541 gaagcaccag ctacaatcag ttttggtttt acttcttggg cttgtttcaa gatagcatca
    30601 aagtctaaga gttccgtttc aggatcaaca ctataagaaa caaagttgta ggtttgacca
    30661 gagaagctaa caggagcccc atgagtcaaa tgaccacctg atgccaaatc cattcccata
    30721 accgtatcac ctggctcaat caaggacatg taagccgcac agttagcttg gcttcctgaa
    30781 tgtggttgga cattggcaaa tttagcaccg aaaatttctt ttgcgcgttc aatagcaaga
    30841 gtctctacaa cgtctactac atcagttcca ccataataac ggcgtcctgg gtaaccctcg
    30901 gcatatttat ttgtcaagat agacccttga gctgccataa cagccttgga aactacgttt
    30961 tccgaagcaa ttaactcgat attattttgt tggcgttctt cttctttggc aatagcattc
    31021 cagagatcag catcatatgc tttaaaatca tctttgtcaa aaatcatagg tcttctcctt
    31081 tattgtgtga ctagtccatt agtttgattt tacaataaga aaatcaaact aaaagatgcg
    31141 aataaaccgt ttctgcattt tatcacaagt atagccaact ttttcataaa atgcatgagc
    31201 acccagacga tgattggcag aatttaagcg gataaaccca taaccacatc tttttgcttc
    31261 ttcttccaac ccttgtagta aacttttacc aataccttga ccttgcgctt gaggtgaaac
    31321 tgctaaagct aagatattaa atcctgcttt ggaatagagt gattcgtaaa cttcagcgtg
    31381 gacatatcca agtaagacat gattagctgc atcctcatag ccaagtagga aatgatggga
    31441 atcctgagac agtctagcta gttggctagc cgtttcctct ggactaaaag tataacccaa
    31501 agcctcttgg ttgatgtcac atatcgcttt cacatctgtt tcttgcaaat ctcttagcat
    31561 ttcaagcctc ctcaaaagaa atctctggca accgagcaag aatatcttct cgtttaattg
    31621 cgccttggcg taagattttc accttgtctc cagacaaatc cacaatagtt gaatcctgtc
    31681 cagttagaaa agcatcgtct tccagaccca gaacctcttg gtcaaaatcc ttcagaattt
    31741 gttcaaaggt tacaccactt gcctgacctg agatattggc agacggccca atcaagggac
    31801 ctgtctctcg aattaaatcc agtgtgatag ggtgactggg catccgaaat ccaatagttg
    31861 caaggtcaga atttacccaa tagggaactc ggtcattggc ttcgagaata atggtcaagg
    31921 gacctggcaa aaaggtctct acaagttttt gtagataagt tggctgattc ttagaaaagt
    31981 gcaagatatc ctcgaaagag gcgatattga gattgagtgc cttatctcta ggacgacgtt
    32041 tgagttggta aacatggtca actgcttttt catctaaggc cttggcaaaa agaccataaa
    32101 cagtctctgt aggtagaacg acagctccac cattttccaa ctcttgtcta atcctgtcca
    32161 tcatcaacca caaccatcct attttgacca aattggtctt tgagtgttcg aacttttttt
    32221 tcaggaagat gttttctaaa aagttcggga acactttgac cttgcttgta tccaatttca
    32281 aggtaaatct taccaccatc cttgagatag tcttttgcat cttccgcaat tctacagtaa
    32341 atagctaggc catcctcgtc tgcaaagaga gctagatgag gctccgaatg caaaacattc
    32401 aaacctacct ctgactcatc ttcacgagag atatagggtg gattggatac aattatatca
    32461 tatttttcag aaatttctgc aaaacaatca gattttttaa aaaatatatt aagattttga
    32521 tcgctagcat tctctgatgc aagctctaag gcctcttgag aaacatctgc tgctgtcact
    32581 gaccaatctg gtctattttt tgctagagcg agagcaatag ctccactacc tgttccaata
    32641 tccagaactg agagattcgt ctcaagattt tcagttagaa taagctccac taactcctct
    32701 gtttctggac gaggaatcaa aacccgttca tccaccttta aatgcattcc ataaaaatct
    32761 gcctgtccaa tgatgtactg agctggcttg tgagctgcta gttgctggta aatatcttct
    32821 acaaattgtt tttcttcctc tgttgtcacc tcctgctgga gggcaaaaat aaagtctgta
    32881 aaagatagat ttttcagact acgatagaca aaagagaggc tttccgcttc ctctccttgt
    32941 cttatcaact cttcttcaaa atttgaaaat aattgagcta atttcattat ttgtttaatt
    33001 cttctagttt ttgtgtttgg tcataaagca ccaaggcatc cacaacttcg tccaatttac
    33061 cagacaaaat cgtatctagt ttttggaggg tcaagccgat acggtggtct gtgacacggt
    33121 tttgtgggaa gttataagtt cggatccgtt ctgaacggtc accagtaccg attgtcgact
    33181 tacgctcagc gtcttgttca tcctgagcaa tctgagcaaa gtggtcagcg acgcgtgcac
    33241 ggataatctt catagccttc tcgcggttct tctgctgggt acgttcttcc tgcatctcaa
    33301 ccttgatatt ggttggcaag tgaacgatac gaacggcagt cgcaacctta ttgacgttct
    33361 gtccaccagc accagaggcg tgatagatgt cgacacgaag gtcttttgga tcaatgtcgt
    33421 attcaacctc ttcaacttct ggcataacaa gaactgtcgc tgtcgaagta tgaacacggc
    33481 cttggctttc tgtcacagga acacgttgca cacggtgggc acctgattca tacttaagct
    33541 tagagtatac agactgacct gaaaccatag caaccacttc tttaaaacca ccgacaccat
    33601 tcatagaggc ttccatgact tcaaagcgcc aaccttgggc ttccgcatac ttttggtaca
    33661 tagttagcaa atctccagcg aaaagtgccg cttcgtctcc accagctgct ccacggattt
    33721 caaggatgat attcttgtca tcgtttggat cctttggaag gagcaaaatt ttcagttttt
    33781 cttcatattc ttctttttca gccttggcat ctttgagttc ttgcttggcc atttcttcca
    33841 agtccgcatc tccgcctgat tccttaatca tctcttcggc atcgacgata ttttgaagga
    33901 cttgtttata ctcacggtag gctattacgg tgtcacgatt ggaagcttct tcttttgaaa
    33961 gctccataaa acgcttggtg tctgaaacga catcagggtc actcagcaat tctcctagtt
    34021 cttcataacg gtcttctaca gcttgtagtt gatcatagat gttcattttt cttcattctc
    34081 cttattgatt tcaggggcaa aataatgttt acggcaaacc gagatatagg tttcattacc
    34141 accaatctgg atctgttctc catcgtaaac gggcagtcca tcctgtgttc gcaacaccat
    34201 ggtcgccttt ttcttgcaat actgacagat ggtcttgatt tcgtcaatct tgtctgctaa
    34261 aagcaagaga tatttggaac cttcgaacaa ttcattgcga aagtcatttt tcaagccaaa
    34321 agccatgacg ggtatgtcta actcgtccac aacacgagct aggtcataaa catggtggcg
    34381 tttgagaaac tgggcttcat cgaccaaaac acagtaaggt ttttctggta ggtctcggat
    34441 atagccaaag atatccgttg tttcctcaat cgcaagggca gggcgtttca tgccaattcg
    34501 actcgacaca tagccaacac cgtcacgcgt atccagagcc gaggtcataa tcacaacacc
    34561 ttttccttgc tcctcgtagt tataggccac tttgagaatc tcaatcgttt taccagagtt
    34621 catggtccca taacgatagt acaactgtgc catgtttctt gcttcacgtc catttctaaa
    34681 tttttgctac attctagtat atcataattt tcttaagctt taaacggcaa aatgtggtaa
    34741 aatggaagaa atcaaaacta gtggaggaag ctattatgcc atttgtacgc atcgatttat
    34801 ttgaaggacg cacgctcgag caaaagaaag ctcttgctaa ggaagtaacg gaagcggttg
    34861 ttcgcaacac tggagcacct caatctgctg ttcatgtcat catcaacgac atgccagaag
    34921 gaacttattt cccacaaggg gagatgcgca ccaaataagc tagcttaagc agaattgctt
    34981 aggctttttc aatctccaag tagcacccat tgaagaaata gtctaaattt gttacaattt
    35041 gaaaagagac ttggaaaatt ccaagaaaag agcaattaat taaaggaaac attatgatta
    35101 cacgtgaatt tgataccatc gctgctatct ctactccact aggtgaaggg gctattggta
    35161 ttgtccgcct gagcggaaca gacagttttg ctattgtgca aaagattttt aaaggaaaag
    35221 acttgaacaa ggttgccagc cacactctca actacggtca cattattgat cctctgactg
    35281 gtaaagtcat ggacgaggtt atggttgggg ctatgaagtc tccaaagacc ttcactcgtg
    35341 aggatattat cgagattaac acccacggtg ggattgcggt gaccaatgaa attctccagc
    35401 tagctattcg tgaaggggct cggttggcag aacctggtga atttaccaaa cgtgcttttt
    35461 taaacggtcg cgtagacttg acacaggcag aggctgtgat ggatatcatc cgtgccaaga
    35521 ctgacaaggc catgaacatt gcggtcaaac aattagacgg ctccctttct gacctcatta
    35581 acaatacccg tcaagaaatc ctcaatacac ttgcccaagt tgaggtcaat atcgactatc
    35641 ctgaatatga tgatgttgag gaagctacta ctgccgttgt ccgtgagaag actatggagt
    35701 ttgagcaatt gctaaccaat cttcttagaa cagcccgtcg cggcaaaatc cttcgtgaag
    35761 gaatttcaac agctatcatc ggacgtccca acgttgggaa atccagcctt ctcaacaacc
    35821 tcttgcgtga ggacaaggct atcgtaacag atatcgctgg gacaacacga gatgtcatcg
    35881 aagagtacgt caacatcaat ggtgtacctc tcaaattgat tgatacagcc ggtattcgtg
    35941 aaacagatga catagtggaa caaatcggtg ttgagcgttc gaaaaaagcc ctcaaggaag
    36001 ccgacttggt tctactagtg ctaaatgcca gtgaacaact gactgcgcaa gacagacaac
    36061 ttcttgaaat tagccaagat accaatcgca ttattctact taataaaacc gacctgccag
    36121 aaacgattga aacttcgaaa ctacctgaag acgttatccg tatttcagtc cttaaaaacc
    36181 aaaacatcga caagattgaa gagcgaatca acaacctctt ctttgaaaat gctggcttgg
    36241 tcgagcaaga tgctacttac ttgtcaaacg cccgtcacat ttccctgatt gaaaaagcag
    36301 ttgaaagcct acaagccgtt aatcaaggtc ttgagctggg gatgccagtt gatttgcttc
    36361 aagttgactt gactcgtact tgggaaatcc tcggagaaat cactggggat gctgctccag
    36421 atgaactcat cacccaactc tttagccaat tctgtttagg aaaataagaa aaatccatga
    36481 tccttcattc ggtcatggat tttattgtct ttattagtaa tctggtctta agacccctgt
    36541 tacagttgcc ttagttgctt cgtagtcgcc atctacgaca accttgataa tgcgtttggc
    36601 atcttcttct ggtgctggaa caagaggtag acgagtgggt ccagcttcaa atcccatata
    36661 gttaagaatt gccttaactg gagcaggact tggataagag aagagagcat taaccttagg
    36721 aatgaattta cgctgaattg ctgcggcttt cttcatatcg ctttctgcaa tggcagtaaa
    36781 catctcgtgc atttcatccc catttgtatg agaggcaaca gaaataaccc catccgcccc
    36841 aaggttcatg gcatggaaag catctccatc ctcacctgta taaatcaaga actcttcagg
    36901 cttgtgctca atcaagtaag ccatattagc caagctagta cattctttga caccgataat
    36961 atttggatgg tcagccaagc gaagcatggt ttctggagtc aattcgacaa ctacacgccc
    37021 tggaatgtta tagataataa ttggtaggtc agaagcatct gcaatagcct taaagtgctg
    37081 atacatccct tcttgagaag gtttgttgta gtaaggaaca atagcaagcc cagctgcgaa
    37141 accaccaaat tccgctactt ctttgacaaa ctcaatagag tcacgcgtat cattagtacc
    37201 tacacccgca atcaaaggaa cgcgtccatt gacaaccttt tgtacagccg caaacaactc
    37261 caactcctca tcgtgggtca aagttggact ctcagcagtc gttcctgcga gaagaattcc
    37321 atccgtatga tgggccaata aatgctcaat caaggctgga atagcatcaa agttaatgga
    37381 accatcctca tggaaggggg taataaaggc tgtaatgatt ttacattctt ttaaatcttg
    37441 ataagacacg aaaacacctc tctatttcaa agaaggagtt catctgaact cctaaacgat
    37501 atgactattt taattcaaat ttcaattcag ctgttggacg aaccaatcca cgttcatgaa
    37561 gagtttcagc aatctgaact gagttccaag cagcaccttt gagaaggtta tctgaaacaa
    37621 cccacatgtg aattcctttt tctgcatcca agtctttacg gatacgacca acaaaggtat
    37681 cacgtgaacc aactgcattg atggcttgag gatagatttg atgaactaca tcatcttcaa
    37741 gaacagcacc tgggaaggat gcgatagctg ctttgacttc ttcaattgga gccacttcct
    37801 ttgtttcaat ataaactgac tcagagtgag ctgacaagac tggaatacgc acacatgtcg
    37861 cagatactgc aatgctatca tcttccataa ttttcttagt ttccttggtc atcttcatct
    37921 cttcgtacgt gtaatcatta tcagtgaaga catcaatttg tggaagagcg ttaaaggcga
    37981 taggataatg tttcttgtca ccacctgaag gcaagatttc cgcatgcaaa tcacgtggtt
    38041 tcactccatc attcaagacc tcacgaagtt cacgttgtgt ctcaagaatt gctcccatac
    38101 cagcacctga aacggcttga taagttgaaa caatgatacg gtccaagccc catttttggc
    38161 gaaccggctc aagagccacc atcatttgga ttgttgaaca gttagggcag gcaatgattc
    38221 cgttgtgggc atcaagtgca tgagcattga cctctggaac aaccaaagga acatctggat
    38281 tttgacggaa ataagatgta ttatccacta ctaccacgcc agcttttact gcgtatggtg
    38341 catacttagc tgatgtcgaa ccacctgctg aaaagagagc aatatcaact ccttcaaaag
    38401 ctgtttcagt cgtttcttca atcgtaatat cttgatcttt aaatttcaat gacttacctg
    38461 ctgaacgtgc agaagcaagg taacggattt tatcgattgg aagtgttgat tcttccaaca
    38521 tttttatcat ctgagcaccg acagcacctg tcgcgccgac tacagcaact gtatatccca
    38581 taaataacct ctttcggaat tttctaaaaa tttctataat agaagtatta tactactttt
    38641 tccatgaatt gcaaagcttt ttcatcattt tttggaaaat aaaaatcccc aatcgctaga
    38701 ctagggatta agaggcatct tcatgtgatg agcaggttca cacaactcat caaggtccgc
    38761 tcctgcgtta tgacctcctt atgctcaata gtagcccgaa gactacctat cgactcatcg
    38821 catctactat tctactagat agagtcattt ttgtcaacag ccaaaactct ttatactctt
    38881 cgaaaatctc ttcaaacttc gtcagcgtcg ccttgccgta tgtatggtta ctgacttcgt
    38941 cagtttcatc tacaacctca aaaacatgtt ttgagctgac ttcgtcagtt tcatctacaa
    39001 cctcaaaaac atgttttaag ctgacttcgt cagttctatc tacaacctca aagcagtgct
    39061 ttgagcaacc tgcggctagt ttcctagttt actctttgat tttcattgag tattagtttt
    39121 atttacacag gtgcataaga aatatattgg aaaaattggg ggcagacata acaaaaaccc
    39181 ttgtaaatca agggcttttc tgtctattta atgctaattg ccgggattga accggcgacc
    39241 tcatccttac catggatgcg ctctgccaac tgagctaaat cagcttactt aagaagtata
    39301 ctatattcag aaaaacttgt caagtttcct tagaaatttt ccataggaaa aagccaggta
    39361 agaactacct agcttatctt cttctattta cttaaatcaa ttcgacgacc aattttacca
    39421 ataataatcg ctccaataat caatgaagca aattcaccga ttcctgttgt aaaccaagta
    39481 aggaagaatg gtaattctgc tacaatattt aactctgcag cgatagtaaa catggaaatt
    39541 gaaaagagga ttgaaaagaa gaaatgatct tttcgaatca atccgttaaa gaggtaatcc
    39601 ttgctatatt ttgcaaaaag ccaaacacct aaactgagga atactaaggt tgaaccacca
    39661 ccaacaaaga catctagcag tccgaagcta aagaaattag caatcataca accgatggta
    39721 actccgatga tgtacttagg attgtaaaaa gccataaagt tcatcatttc tgaaatacga
    39781 aactgataag caccatagct gatggcattt aggggcggtg tgacagtcaa aacgacgtag
    39841 atagcagcga cgattgcaat atctgcaaca tcacgaatag ttaatttttt catcttttct
    39901 cctttggcgg ttatccgcgt gtaatatgct tggtgaaaga agctaagcac caagggttga
    39961 ttcattcaac cttactagta tagcacaata gcctgcttta tgctatactt aaagcatgaa
    40021 aaaacctatt caaaaatttt ttaacaatga aatcttagcc tatctctttt ttggccttgc
    40081 gacaactcta gtttcgattc tctcacgact agtcatttat caactaagtc atcaggaact
    40141 ccttgctacg gccttggcaa atattatcgg tatcttattt gcctttatca caaatgatac
    40201 gattgtattt aagcaaaaaa agaaaaatag acttatccgt ttagtgaaat tttctcttgc
    40261 tcgcctttct acttttctgt tagacttgtt tttaactttt ctctttgtaa cccaatttcc
    40321 tcacatcata gggcaattcg taactgaaaa cattgataag ataaatgcta ttgaaacaat
    40381 aattgcacaa atattcatta ttatcatcaa ttatatcttg agcaaggtct atatttttag
    40441 aaaataatgc tccatttatg agccttttaa ttgccttcta taatgattta ggatacaatg
    40501 aaacacgaaa cattgaaagg aaaacagtat gttaaaaaat ctaaaatcgt tcttgcttcg
    40561 aggaaatgtt attgaccttg ctgtcggtgt tgtcattgcc tctgcttttg gtgctatcgt
    40621 tacttcactt gtaaacgaca ttatcactcc tcttatttta aatcccgctt tgaaagctgc
    40681 taaagtcgaa cgtatcgctc aactttcttg gcatggagtc ggctatggta actttttaag
    40741 tgctattatc aattttatct ttgtgggtac cgccctcttc tttattatca agggcattga
    40801 aaaagcacag aaactgactg gcataaagaa agaaaaaact gccgaaaaaa aaccaaccga
    40861 attggaagtc cttcaagaaa taaaagctct ccttgagaaa aaataatcga ttaaaaggat
    40921 ctagcgcaaa gctaaatcct tttttcttta ctctttgggt aacttgcctg ctttttcaag
    40981 catttttttg ataagataag gcatcttaac attctcccgc ccttttttct caatcagttt
    41041 tttcacaaat tctggcattt gtaaatcttc agattcagct aaaatgtttt tcgtctcgtc
    41101 tgaaggaact aactcatcaa aggtctcttc ttctgggaga aattccttaa actcttgatt
    41161 ttcattgact ctaactgtat tgaccaaagc atcaatcaaa cgagaatctg tatttggcat
    41221 tggtggacga tggtagttta ccccaaattc ctggcataag tcataacatt ctacatcatt
    41281 gtcaaacaag acctcaatat gctcactgat gaaactaata ggtacaaaaa tataatggtc
    41341 tggatgttct gtctgttctc tgagatactc caaaacatct ggtttaatcc atggaatacc
    41401 aatatcactc tcactctgcc aagtgttggt atattgttct gaactcaagc ccagtttttc
    41461 agcgactagc ttgctatttt cgaaaatttg gtctatataa ggatcaccaa agtccaaggc
    41521 aaaaatgggc acactatggg ctgaaaagat gactttaaag ctgtcttgct ttacttcttc
    41581 ttttaaaatc ttagcaattt catctgccca atagtttaag agcgcttctt cctgatacca
    41641 gtccttaatg accaaaaatt gaatttgttt gctttctaaa aatttttcat agcccatgac
    41701 agagtagaaa gaataatggg gctccaaaat caagcaaata cactgttcaa ttccgtctgc
    41761 ttccatttga ccgatcacat ctggaataaa gggactggaa aacttattag caaagtagac
    41821 actgtattca ttccccagcc tagcttctac aaaggcaacc tcttgacggg taattttttg
    41881 cagaggcgtg cctccaattc gtacataatt atcatagaga gtctgaatct cgtggtcttg
    41941 gggtctcacc ccacgacgaa tatttgtgaa aaaatcagct acaccttcaa aggtaatctc
    42001 ttctggtgaa ccgaaggtca tcattaaaat tgcttttttc atgactgctt ccttgtgatg
    42061 tttttatcaa gtttatttta tcattaatta atcgataagt aaacgctaat atagggacat
    42121 tctcaatctt ctgtcttttg tttttctctt ctttctatga tacaatggaa aaaataaatt
    42181 caaaaggagt ttttttatga cttatccaaa tctcttggac cgcttcttaa cctacgttaa
    42241 ggtcaacacg cgctctgatg aacactctac tactactcca agtacacaga gtcaggttga
    42301 cttcgcaaca aatgtcctaa ttcctgaaat gaaacgtgtt ggactgcaaa atgtttacta
    42361 tctaccgaat ggttttgcta ttggaacctt gccagccaac gatccgtctt taacacgtaa
    42421 gattggtttt atatcgcaca tggatactgc tgattttaat gctgaaggag tcaatccaca
    42481 ggtaattgaa aactacgatg gtggtgtgat tgaactaggg aattctggtt tcaaactcga
    42541 tccagctgac ttcaagagtc ttgaaaaata tccaggacaa acgctcatca caacagatgg
    42601 aacaagcttg ctaggtgctg atgacaagtc aggaattgct gaaattatga cagccattga
    42661 atatctaact gctcatcctg aaattaagca ctgtgagatt cgtgttggtt ttggtccaga
    42721 tgaagaaatc ggtgttggtg ccaataaatt tgatgcagaa gattttgatg tggattttgc
    42781 ctacactgtt gatggtggtc cactaggtga acttcagtac gagactttct cagccgctgg
    42841 tgctgaattg catttccaag gccgtaatgt ccaccctggt actgccaaag agcagatggt
    42901 caatgccctt cagctagcaa ttgattttca taatcaactt ccagaaaatg accgacctga
    42961 gttaactgaa ggttaccaag gtttttacca tctaatggat gtgacaggta gtgttgagga
    43021 ggtgcgtgca agctacatca ttcgtgattt tgaaaaagat gcctttgaag cgcgtaaagc
    43081 atccatgcaa tctatcgctg ataagatgaa tgcagaactt gggagctacc gtgtcactct
    43141 caacttgaca gaccagtact acaatatgaa agaagtcatt gaaaaagata tgactccaat
    43201 taccattgct aaagccgtta tggaagatct aggtatcacg cctattatcg aaccaatccg
    43261 gggtggaaca gacggctcta agatttcctt tatgggaatc ccaactccga atatctttgc
    43321 aggtggcgaa aatatgcacg gacgttttga atacgttagc cttcagacta tggaacgtgc
    43381 agttgatacc atcattggca tcgtagctta taaaggctaa aaagacgagg tagctcagct
    43441 acttcgcctt tctttttatt ctactggttt ttcttgattt ccagtagttg tagaagattc
    43501 tgttgtttca ttttctgaag ttgattcagc aggtttagaa tctcttgtat tgcttggttt
    43561 gttttcgtcg ctagcaattt caatgttaga ttctgcagtt gcgtttggtt ggttctcagc
    43621 actggtgtta tcactatttg cttcagcatt tcttgctgga cttgtttctt cacttgcgct
    43681 agcttttgac tggatttgat gattcaaaac tagaatagct tttgtcgatt caagtaaagc
    43741 tgttttgtct ttactcttag cagaaagttg atctaataat gcatccacct tatcaaagtc
    43801 cgcatcagat ccattattac tttctaaata agagtgaagc gacatgagaa tatcgtagag
    43861 tttttgatag agtacaagtg tctgagaatc ttgctcagca ttttcctttt cttgttgaag
    43921 ggcgctagcg atacgagtca agacatcttt tacctgactg tttacttcat ccaagtctgc
    43981 atcagccttg tttgtggcag cttttagatt ttctacttct tctgccaagg attgtctgat
    44041 tccttcttca tggatttgtt ccaagagttg atttaccttg ctcaaaagac tttctacttc
    44101 ttccttgcta tctgtcgcag attattggtt gccatctacc atgtactcct aaaacaggag
    44161 agttataatc caagattaca aggccttaca gaaataagaa atccagataa gacaatgttc
    44221 gtccaagacg ctattcgctt cgcacagcag cacggattca atatgcttta attttaaagt
    44281 ttaggtgtca agacctcttt ttagtgtgcc caaaatttag agaagtaatc aatcaactaa
    44341 cttttatttt tttcaaactt tcagtaaact gacctaaagc taactcaatc tgtctttgta
    44401 gatgcttctg ctatcagcta gaagttgatc tacttttgcc aagactgcct tctcatcaaa
    44461 agttccaggt tgatagttgg attgcaggga tggaatcttg tttttcaaag ccgcttcata
    44521 tcccttagtt tgaaccttga tgtagtgatt gtggtcgcca tgaggaatca caaaaccttc
    44581 tgaatcttca cttataattc gattggcatc aaaaccatga ccatcttctt cctcatgatg
    44641 gacatgtagt gacggattac ttaatacaga actagaagaa cttcctacct cttccgtgtt
    44701 agagtgtgat gggggattgt taagagatga cttaggaata tagtgatagt gatccccatg
    44761 tcttactata taagcatcac ctgtatctct gacaatatca ttagggttaa agacatatgt
    44821 ggctgctaat tcacctgccg acaagtcact ctcaggaatg aaatgatagt gaccaccatg
    44881 tggtactata gtagattgaa atagaatatg agcaaattga taaggggatt ttaaagtaat
    44941 ttctaacaat gatttagaaa ctatgatgtg ctattctaaa ttcaactcac tatatataac
    45001 catcatcggt agtataacgt ccctgtaatt ttgctacaga tacttctgca ctagctcctt
    45061 tatcgtcttt accatgttct tgtttttggc gattgatttc atcttttgtt cgtacatttt
    45121 ctgcatgagc ttgatcttta aggtaaacat aatactttcc atctacctta ataatatatc
    45181 ctcccttaac ctaactgacg atatcttgat ctttcggctg atagttgggg gctttcatta
    45241 atagctcttc actaaagagc gcatcaaaag gaactttacc attatagtag tgataatgat
    45301 cgccatgaga agttacataa ccttgatctg taatcttaat aacaatttgt tttgcttgaa
    45361 ttccttcttt ttgactaacc tagtctggag tcaaattttc agtcttctta gtgtctttat
    45421 tactgtttac atatgaaaca cgatttttat ctgtattggc ctgttagcta tgttggttca
    45481 gagcataaac acacagactt aaggaaagga taacaacaga tccagctgct atatatttct
    45541 ttttaaattt cataattacc tcatttctat aattatttat atgatgtctt cattattaaa
    45601 tgattaaata aattaattaa ccaattaatt aactagtaaa tattccacct ctttttaagt
    45661 tgtatgtcaa gaaattttat atattaataa taaaatgaaa ttctcccaaa gtcagagttt
    45721 tatttctaac ttttgagaga acttcatttt tgattcagac tttttctact gctattcctt
    45781 acgctatgag atcagataaa ttctttttta tcacttctcc acttggcaat cttaattcaa
    45841 tcgttccatc catattgaat ataacactat ctaagcctaa tccgtaacta gctgtaaatt
    45901 tttctaattt ttcttgtaca ggatctactg ctggagcttc ctctaatgct ggatctaaca
    45961 tagggtcact ccccacattc ccttctggat tcaacattcc attatccgtt gagttttctg
    46021 gttttacagg tttttcgttt ggtgcctctg gtaaagaatc tgctggttta ttttctgttg
    46081 gttggttctc aactgttcca gtagatactt ttccattttc agatggttta ttttcaccat
    46141 ttccttgagg tgcttctcct gtaaaatctg ccatattctt tttaatgact tctcccgatg
    46201 gtaaatataa ttcaattgtt ccgtccatat taaacaagac attttctagc ttcatcccat
    46261 aactttcagc aaattttgct actttttctt gtacaggatc cactgtagga acttcttcta
    46321 acgttgaatt actagtacta ttcccagttt cagaaagttt ttctttttct accttctcac
    46381 tagtctttgg ttcttctacc ttttcatcaa gttttgagtt ttcttgtgct ttattccttt
    46441 taaattgtgg tagaatactt ggtttatcag tttgattttc tttttccaag ataggtactt
    46501 ccacaatata agtcgattga ttgtccaaat aagcatttgc catgaaggtt acaggaattt
    46561 tatttccggc cgttctggtt gttccttggt ttaatttcgg aatcggtaat ttgatttcac
    46621 caactttata gttattttct aaataagcat ttccatgaaa ttcatcaaac actctgacta
    46681 aagcatcagt tcctttaggc actgcaaatt gagggttcac tcttaaataa gtatcccctg
    46741 catggaaagg atagaaaatc gtttgactgg ccattttgta agctaaagag gttggaactg
    46801 taaatgtacc atcataactt acttctggat aatcttttga agcgatagta tacttaaatg
    46861 tttgtcctgg taaataaggt tgatctaatt caaagtttgc aatattccct actccttctc
    46921 caaatacttt accagatact ttctccaata cttttccatc tggtgttatt aattttacta
    46981 gcatattgat acctaatttt ttctccaatt caggcggaaa actaaaagaa acgcgttttt
    47041 gaccattggc tagagtaaag ttttgattat taaacgtact attttttaac aaattaacaa
    47101 cattcgttaa ttcttctcca gtataaactt tattcccttc ttttttagca actccttctt
    47161 cgggtttaaa cagttcatag ttactgtgag aatgaccaat tccaaccggt ttatgttcat
    47221 caatcggatc tgcatgatgg tgatctccat gcggataaat aatcgcattt ttttctttat
    47281 tcacgacaat actttcacgt ttgacaccat attgtttcat aatgccagca attttttctt
    47341 cgattttttt atctaaatct ttcatttctt tggcattact tggataatcc tgttcatgag
    47401 atgacaaaga atctaatcca ttatgactag ttttaacttc ctctaaatgt ttttgcgcag
    47461 ccttaatttg ctcttctgtc aagtccttct tgaagaaata atgattgtgg tctccgtgac
    47521 tcatgacaaa acctgattca tcttcagcga taatacgatt agcatcaaat ccgtatccat
    47581 cttcttcatg tttctcatgt gaagttcctg gattgattgg aagagatgga gaaggtgttg
    47641 ctagactatt gtttggaaga gtcggttgcc caatttgatt tgattttgga atgtaatgga
    47701 aatgatcacc atgtcttaca atataagctg tagccgtttc ttcaacgata tcttttggat
    47761 taaaaatata accatcagat gctgaagaga gctccttact tgtcgttaaa gaagaaggat
    47821 tgcttgaaag actgcctaga ctagacacta cttcattagg ttttgcattt gtagaaactg
    47881 tagaaccagt tccactgata ggcaccattc tggcaatctt ttcttctaag gcagaaagct
    47941 tgctgtaagg aataaagtgg taatggtcgc catgcggaat cgcaactcca tttggtgtac
    48001 gactgataat cttagcaggg tcaaagacca ggccatctga ttcactgtaa cgttgggcgc
    48061 taggtgaatc atagagttcc ttcaaaagac tctggagatt ttcagattta tttgctggct
    48121 tgctagttga tccttttgct acagattgcg tgttattgtc actagctgtt gaagaatagc
    48181 ttaactgact cggttgcata ttttttccag ccagatgtgc tttagctgct gctaattcac
    48241 tagcagataa atcgcttttg ggaatgtagt gatagtgacc tccatgagga acgatataag
    48301 cattacccgt atcttcgata atatcagctg gattaaagac ataaccatca tttgtcgtat
    48361 atcgtccctg agaccttgct acagcaacat tagagttaac cttctcatta tctttgacat
    48421 gttcttgttt ttgacgattg atttcatctt tagttcgaac attatcagca tgagctgcat
    48481 ctttcaggta gacataatat tttccatcga ccttgatgat ataaccaccc ttgacttcat
    48541 tgacaatatc agcgtcttta agttgatagt ttggatcctt catcaagagt tcttcactaa
    48601 agagggcatc ataaggaact ttcccattat agtaatgata gtggtcaccg tgtgacgtta
    48661 catagccctg atctgtaatt ttgattacaa tttgctcagc ctgaattcct tctttctggc
    48721 taacctggtc tggtgtcaag ttttcacttt tctgacttga ctggctgcca tccacataag
    48781 agacacgatt attgtcctta ttttcctgcg aacgatgctg gtttagtgca taggcacata
    48841 gactcaagga tacgataaca gctgatccag ctgctatata ttttttacta aatttcataa
    48901 atccctcatt tcaataaatg atgaagtttt ttctcaactt cttttacttt attaaatagt
    48961 tttctaaacc ggttatttaa ccatttaatt aaccagtaaa tagtttacta tttaaaatta
    49021 cttttgtcaa gtttctgtta cgtttttcta aaaaagagaa gtaacacgaa aggttacttc
    49081 tccataaaat atgctccatt cattttacta ctgtatagga gccggttgac ttttttttaa
    49141 caaagccaag agactatcta cttctgctga aatagtgtta ttatctttcg ttccgagaag
    49201 aagactactt tttagaccag tcaatgtctc catagcattt tgtctaatac tag
//
LOCUS       DBERCW010000011        47088 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.011, whole genome shotgun sequence.
ACCESSION   DBERCW010000011 DBERCW010000000
VERSION     DBERCW010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 47088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.011"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            60..929
                     /locus_tag="ACL72M_000810"
     CDS             60..929
                     /locus_tag="ACL72M_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS0715967.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="ACL72M_000811"
     CDS             933..1889
                     /locus_tag="ACL72M_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS0715968.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="ACL72M_000812"
     CDS             1889..2653
                     /locus_tag="ACL72M_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715969.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="ACL72M_000813"
     CDS             2653..3363
                     /locus_tag="ACL72M_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0715970.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3777..4433
                     /locus_tag="ACL72M_000814"
     CDS             3777..4433
                     /locus_tag="ACL72M_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGS0715971.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            4541..5636
                     /gene="prfB"
                     /locus_tag="ACL72M_000815"
     CDS             join(4541..4612,4614..5636)
                     /gene="prfB"
                     /locus_tag="ACL72M_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGS0715972.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5654..6346
                     /gene="ftsE"
                     /locus_tag="ACL72M_000816"
     CDS             5654..6346
                     /gene="ftsE"
                     /locus_tag="ACL72M_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGS0715973.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6339..7265
                     /gene="ftsX"
                     /locus_tag="ACL72M_000817"
     CDS             6339..7265
                     /gene="ftsX"
                     /locus_tag="ACL72M_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGS0715974.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            7551..9731
                     /locus_tag="ACL72M_000818"
     CDS             7551..9731
                     /locus_tag="ACL72M_000818"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGS0715975.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            9783..10598
                     /locus_tag="ACL72M_000819"
     CDS             9783..10598
                     /locus_tag="ACL72M_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS0715976.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            10738..12081
                     /locus_tag="ACL72M_000820"
     CDS             10738..12081
                     /locus_tag="ACL72M_000820"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0715977.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            12297..13487
                     /gene="metK"
                     /locus_tag="ACL72M_000821"
     CDS             12297..13487
                     /gene="metK"
                     /locus_tag="ACL72M_000821"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGS0715978.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSEEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIKK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            14040..14975
                     /locus_tag="ACL72M_000822"
     CDS             14040..14975
                     /locus_tag="ACL72M_000822"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGS0715979.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            15009..16046
                     /gene="holA"
                     /locus_tag="ACL72M_000823"
     CDS             15009..16046
                     /gene="holA"
                     /locus_tag="ACL72M_000823"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS0715980.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            16219..16824
                     /gene="sodA"
                     /locus_tag="ACL72M_000824"
     CDS             16219..16824
                     /gene="sodA"
                     /locus_tag="ACL72M_000824"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGS0715981.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELTAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            16981..17511
                     /locus_tag="ACL72M_000825"
     CDS             16981..17511
                     /locus_tag="ACL72M_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGS0715982.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            17532..18434
                     /gene="rlmN"
                     /locus_tag="ACL72M_000826"
     CDS             17532..18434
                     /gene="rlmN"
                     /locus_tag="ACL72M_000826"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0002935 - tRNA
                     (adenine(37)-C2)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0070040 - rRNA
                     (adenine(2503)-C2-)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGS0715983.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVSCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDID
                     AACGQLRFNTMKRDRQKAVAAVNP"
     gene            18434..18916
                     /locus_tag="ACL72M_000827"
     CDS             18434..18916
                     /locus_tag="ACL72M_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS0715984.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQPL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            18918..20459
                     /locus_tag="ACL72M_000828"
     CDS             18918..20459
                     /locus_tag="ACL72M_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0715985.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(20515..21318)
                     /locus_tag="ACL72M_000829"
     CDS             complement(20515..21318)
                     /locus_tag="ACL72M_000829"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGS0715986.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(21402..21615)
                     /locus_tag="ACL72M_000830"
                     /pseudo
     CDS             complement(21402..21615)
                     /locus_tag="ACL72M_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22094..22303)
                     /locus_tag="ACL72M_000831"
     CDS             complement(22094..22303)
                     /locus_tag="ACL72M_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715987.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            22473..22745
                     /gene="rpsP"
                     /locus_tag="ACL72M_000832"
     CDS             22473..22745
                     /gene="rpsP"
                     /locus_tag="ACL72M_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGS0715988.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            22765..23004
                     /gene="kphA"
                     /locus_tag="ACL72M_000833"
     CDS             22765..23004
                     /gene="kphA"
                     /locus_tag="ACL72M_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGS0715989.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            23192..23477
                     /locus_tag="ACL72M_000834"
                     /pseudo
     CDS             23192..23477
                     /locus_tag="ACL72M_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            23581..24369
                     /locus_tag="ACL72M_000835"
     CDS             23581..24369
                     /locus_tag="ACL72M_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0715990.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPKMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            24400..24918
                     /gene="rimM"
                     /locus_tag="ACL72M_000836"
     CDS             24400..24918
                     /gene="rimM"
                     /locus_tag="ACL72M_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGS0715991.1"
                     /translation="MNYFNIGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            24908..25627
                     /gene="trmD"
                     /locus_tag="ACL72M_000837"
     CDS             24908..25627
                     /gene="trmD"
                     /locus_tag="ACL72M_000837"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGS0715992.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDDPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            25639..25977
                     /locus_tag="ACL72M_000838"
     CDS             25639..25977
                     /locus_tag="ACL72M_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGS0715993.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(26008..26328)
                     /locus_tag="ACL72M_000839"
     CDS             complement(26008..26328)
                     /locus_tag="ACL72M_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715994.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            26426..26641
                     /locus_tag="ACL72M_000840"
     CDS             26426..26641
                     /locus_tag="ACL72M_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGS0715995.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(26847..27383)
                     /locus_tag="ACL72M_000841"
     CDS             complement(26847..27383)
                     /locus_tag="ACL72M_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGS0715996.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            27809..28147
                     /locus_tag="ACL72M_000842"
     CDS             27809..28147
                     /locus_tag="ACL72M_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0715997.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            28213..30195
                     /locus_tag="ACL72M_000843"
     CDS             28213..30195
                     /locus_tag="ACL72M_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0715998.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            30192..30815
                     /locus_tag="ACL72M_000844"
     CDS             30192..30815
                     /locus_tag="ACL72M_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0715999.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            30812..31312
                     /locus_tag="ACL72M_000845"
     CDS             30812..31312
                     /locus_tag="ACL72M_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716000.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNSQKKDIKELYKKIYES
                     FKEKNK"
     gene            complement(31478..32824)
                     /gene="gor"
                     /locus_tag="ACL72M_000846"
     CDS             complement(31478..32824)
                     /gene="gor"
                     /locus_tag="ACL72M_000846"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGS0716001.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            33089..34288
                     /locus_tag="ACL72M_000847"
     CDS             33089..34288
                     /locus_tag="ACL72M_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGS0716002.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            34272..34973
                     /locus_tag="ACL72M_000848"
     CDS             34272..34973
                     /locus_tag="ACL72M_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716003.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            34975..36234
                     /locus_tag="ACL72M_000849"
     CDS             34975..36234
                     /locus_tag="ACL72M_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716004.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            36358..38355
                     /gene="metG"
                     /locus_tag="ACL72M_000850"
     CDS             36358..38355
                     /gene="metG"
                     /locus_tag="ACL72M_000850"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGS0716005.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            38405..38548
                     /locus_tag="ACL72M_000851"
     CDS             38405..38548
                     /locus_tag="ACL72M_000851"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716006.1"
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDETDEVSSKHSFEVVDETDEVS
                     NHT"
     gene            38686..39006
                     /locus_tag="ACL72M_000852"
     CDS             38686..39006
                     /locus_tag="ACL72M_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS0716007.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            39010..39825
                     /locus_tag="ACL72M_000853"
     CDS             39010..39825
                     /locus_tag="ACL72M_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716008.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGVFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            39900..40826
                     /locus_tag="ACL72M_000854"
     CDS             39900..40826
                     /locus_tag="ACL72M_000854"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGS0716009.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            40922..41158
                     /locus_tag="ACL72M_000855"
     CDS             40922..41158
                     /locus_tag="ACL72M_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGS0716010.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            41151..41849
                     /locus_tag="ACL72M_000856"
     CDS             41151..41849
                     /locus_tag="ACL72M_000856"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGS0716011.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEARI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            41860..42339
                     /locus_tag="ACL72M_000857"
     CDS             41860..42339
                     /locus_tag="ACL72M_000857"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0716012.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            42347..43075
                     /locus_tag="ACL72M_000858"
     CDS             42347..43075
                     /locus_tag="ACL72M_000858"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716013.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            43117..43986
                     /locus_tag="ACL72M_000859"
     CDS             43117..43986
                     /locus_tag="ACL72M_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGS0716014.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAYVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            43961..44401
                     /locus_tag="ACL72M_000860"
     CDS             43961..44401
                     /locus_tag="ACL72M_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGS0716015.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            44524..47070
                     /locus_tag="ACL72M_000861"
     CDS             44524..47070
                     /locus_tag="ACL72M_000861"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGS0716016.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
BASE COUNT        14527 a         8233 c        10224 g        14104 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaacccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttggctat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgactgc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac agcaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa attaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctgggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gccttacaaa tggtgcggca ggtatcttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gtcgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc atcaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttgaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttggccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa catgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagaca atgttttgat tgcttttgga aaccatcaca aacaacatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa tgccagctca gaaaattgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agctaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgta agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagga acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac ttgcaatctc tgaccgagga tatgtactgg aaacagggaa aatcgtccta
     3301 tcaggaacag gaaaagaact cgcctcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcatta
     3421 tagtctggga gactagttta ggttgcagat aaagattgcg aagcaatcat caaatccagt
     3481 ggattgtttt agtcggcaga tggagattac gaagtaatca tcaatatagt ccgggggacc
     3541 tttttagtcg gtagattgag attgcaaaca aatctgcatc tacattgaaa gcttaatttc
     3601 taataattga aaaaatcgaa tgaaaaattt cttaccttca ttcacagagc tcgatttcag
     3661 agctcttttt gctagcttat tcatactttt ctgaatttcg aaaaagaaat gtaagcgttt
     3721 gatagattta caaaaagatt gtataatagg gataagaata gaaaaggaga agtctcatgg
     3781 cagttaaaga ttttatgacc cgcaaggtag tttatattag tccagataca acagtatctc
     3841 atgcagcaga tttgatgaga gagcaaggtt tgcaccgtct gcctgttatc gaaaatgatc
     3901 aattagttgg tttggtgact gagggaacca ttgcacaagc aagtccatct aaagcaacaa
     3961 gtctttctat ctatgagatg aattatcttc tgaataagac aaaagtaaaa gatgtcatga
     4021 ttcgcgatgt tgtcactgtc tcaggctatg ctagtctaga agatgcaact tatctgatgt
     4081 tgaaaaataa gattagtatt ctccctgtcg tagataacca tcaagtatac ggagttatta
     4141 ctgaccgtga cgttttccaa gcctttcttg aaattgcagg ttatggcgaa gaagggattc
     4201 gtgtacgctt tgttacagaa gatgaagttg gtgttcttgg aaaaattgtt tctttgattg
     4261 tagaagaaaa tttgaatatc tcccatacag tcaatattcc gcgtaaggat ggtaaggtga
     4321 ttatcgaagt gcaaatcgat ggatcaattg atttaccagc cttgaaagaa aaatttgaag
     4381 caaatggtat tcaagtggaa gaaatcgctc gcacttcagc aaaagtcttg taagaaggga
     4441 agcccaaagg cttctttttt catgaaaagg ggattagaga aaaagatgga aagaaatgat
     4501 aaaatatgct ataatgaaat aatgtaaaaa aggagtattt atggacattt cagtaattcg
     4561 tcagaaaatt gacgcaaatc gtgaaaaatt agcttctttc agggggtctc tttgacctcg
     4621 aagggctaga ggaggagatt gccatcttgg aaaacaagat gacagaacct gatttttgga
     4681 acgataatat tgcagcccaa aaaacgtcgc aagaattaaa tgaattaaaa aacacttaca
     4741 ataccttcca taagatggaa gagttgcagg atgaagtcga aattttattg gattttttgg
     4801 ctgaagacga gtcagtgcat gatgaactgg tagcgcagtt agccgaactt gataagataa
     4861 tgaccagcta cgagatgact ctactcttgt cagaacctta tgaccacaac aatgccatct
     4921 tggaaatcca tccaggttct ggtggtactg aggcgcagga ctggggtgat atgttgcttc
     4981 gtatgtatac tcgttatggt aatgctaaag gctttaaagt ggaagtgttg gattaccaag
     5041 caggtgatga ggctggtatt aagtcggtaa ctttatcatt tgaagggcct aatgcctatg
     5101 gtctcctcaa gtcagaaatg ggtgttcacc gcttagtgcg aatctcacca tttgactctg
     5161 ccaaacgtcg ccatacctct ttcacatctg tagaagtgat gccagaattg gatgatacta
     5221 ttgaagtgga aatccgtgaa gatgatatca agatggatac cttccgttca ggtggtgccg
     5281 gtggacaaaa cgtcaataag gtttcaacag gtgtacgttt aacccacatt ccaactggaa
     5341 ttgttgtcca atcaacagtg gatcgtaccc agtatggaaa tagagatcgt gccatgaaga
     5401 tgttgcaggc taagctctat caaatggagc aagagaagaa ggctgcagag gtagattctc
     5461 tcaaaggtga gaaaaaggag atcacttggg gaagccaaat ccgttcttat gtcttcacgc
     5521 cttatactat ggtaaaagat caccgaacta gctttgaggt tgctcaggta gataaggtta
     5581 tggatgggga cttagatggt tttatcgatg cttatctcaa gtggcgaatt agctaagata
     5641 gaaaggaact cacatgtcaa ttattgaaat gagagatgtc gttaaaaaat acgacaacgg
     5701 aacgactgct ctacgcggtg tttcggttag cgttcaaccg ggggaatttg cttacatcgt
     5761 aggaccttca ggagcaggga agtcaacttt tattcgttct ctgtatcgtg aagtaaaaat
     5821 cgataaagga agcctatcag ttgctggttt taatctggtt aagatcaaaa agaaagatat
     5881 cccgcttcta cgtcgtagtg ttggggttgt cttccaggat tataaattgt taccaaagaa
     5941 aactgtctat gaaaatattg cttacgctat ggaagtaatc ggggaaaatc gccgtaatat
     6001 caaaagacga gtgatggaag ttttggactt ggttggattg aagcataagg ttcgttcttt
     6061 cccaaatgaa ctctcaggtg gggagcaaca gcggattgcg attgcgcgtg caattgtaaa
     6121 taatcccaaa gtattgatag ctgatgagcc aacaggaaat ctggatccgg ataattcatg
     6181 ggaaattatg aatcttttgg aacggattaa cctacaagga acaactattt tgatggcgac
     6241 tcataatagc cagattgtaa ataccttgcg ccaccgtgtc attgccattg aaaatggccg
     6301 tgtcgttcgt gacgaatcaa aaggagagta tggatacgat gattagtaga ttttttcgcc
     6361 atttatttga agccttaaaa agtttgaaac gaaatggttg gatgacagta gctgctgtca
     6421 gttcagtcat gattactttg accttggtgg caatatttgc atctgttatt ttcaatacag
     6481 cgaaactagc tacagatatt gaaaataatg tccgtgtagt agtttatatc cgaaaggatg
     6541 tggaagataa tagtcagaca attgaaaaag aaggtcaaac tgttacaaat aatgactacc
     6601 acaaggtata tgattctttg aagaacatgt ctacggttaa aagtgttacc ttttcaagta
     6661 aagaagaaca atatgaaaaa ttaaccgaga taatgggaga taactggaaa atctttgaag
     6721 gagatgccaa tcctctctat gatgcctata ttgtagaggc aaacactcca aatgatgtaa
     6781 aaactatagc cgaagatgct aaaaaaattg aaggtgtctc tgaggttcaa gatggcggtg
     6841 ccaatacaga aagactcttc aagttagctt catttatccg tgtttgggga ctagggattg
     6901 ctgctttgtt aatttttatc gcagttttct tgatttcaaa taccattcgt attaccatta
     6961 tttcccgcag tcgcgaaatt caaatcatgc gcttggtcgg agctaaaaac agttatatcc
     7021 gtggaccgtt cttgttagaa ggagccttta tcggtttatt gggagctatc gcaccatctg
     7081 ttttggtctt tattgtttat caaattgttt accaatctgt caacaaatcg ttggtagggc
     7141 aaaatctatc catgattagt ccagatttat ttagtccgtt gatgattgcc ctactatttg
     7201 tgattggggt tttcattggt tcattgggat caggaatatc catgcgccga ttcttgaagg
     7261 tttaggtaaa atagctgctt ttatgaggag attgtaaaat ctcctttttt gctacaagag
     7321 tttttgaaaa gagatgcgca gaagaaaaga gcttccaaag aagtccccca gagaagactt
     7381 cttgatggct aatttgaact tgaaatttgg cgcactagaa attttttaga aaaaagtgta
     7441 atttttttat aaaagccttt acaaaaaaaa ttaaagtggt ataattaaat catagaaagt
     7501 gcaaacgttt tcgtaaaacg tttgcctaaa taaaaataaa ggagatttga atgatgaaag
     7561 atacattcaa aaatgtcttg tctttcgaat tttggcaaaa attcggtaag gctttgatgg
     7621 tagttatcgc ggttatgccg gctgctggtt tgatgatttc aatcggtaag tctatcgtga
     7681 tgattaaccc aacctttgca ccacttgtca tcacaggtgg aattcttgag caaatcggtt
     7741 ggggggttat cggtaacctt cacattttgt ttgccctagc cattggagga agctgggcta
     7801 aagaacgtgc tggtggtgct ttcgccgctg gtcttgcctt catcttgatt aaccgtatca
     7861 ctggtacaat ctttggtgta tcaggcgata tgttgaaaaa tccagatgct atggtaacta
     7921 ctttctttgg tggttcaatc aaagttgctg attactttat cagtgttctt gaagctccag
     7981 ccttgaacat gggggtattc gtagggatta tctcaggttt tgtaggggca actgcttaca
     8041 acaaatacta caacttccgt aaacttcctg atgcactttc attcttcaac gggaaacgtt
     8101 tcgtaccatt tgtagttatt cttcgttcag caatcgctgc aattctactt gctgctttct
     8161 ggccagtagt tcaaacaggt atcaataact tcggtatctg gattgccaac tcacaagaaa
     8221 ctgctccaat tcttgcacca ttcttgtatg gtactttgga acgtttgctc ttgccatttg
     8281 gtcttcacca catgttgact atcccaatga actacacagc tcttggtggt acttatgaca
     8341 ttttaactgg tgcagctaaa ggtactcaag tattcggtca agacccacta tggcttgcat
     8401 gggtaacaga ccttgtaaac cttaaaggta ctgatgctag tcaatatcaa cacttgttag
     8461 atacagtaca tccagctcgt ttcaaagttg gacaaatgat cggttcattc ggtatcttga
     8521 tgggtgtgat tgttgctatc taccgtaatg ttgatgctga caagaaacat aaatacaaag
     8581 gtatgatgat tgcaacagct cttgcaacat tcttgacagg ggttactgaa ccaatcgaat
     8641 acatgttcat gttcatcgca acacctatgt atcttgttta ctcacttgtt caaggtgctg
     8701 ccttcgctat ggctgacgtc gtaaacctac gtatgcactc attcggttca atcgagttct
     8761 tgactcgtac acctattgca atcagtgctg gtattggtat ggatatcgtt aacttcgttt
     8821 gggtaactgt tctctttgct gtaatcatgt actttatcgc aaacttcatg attcaaaaat
     8881 tcaactacgc aactccaggg cgcaacggaa actacgaaac tgctgaaggt tcagaagaaa
     8941 ccagcagcga agtgaaagtt gcagcaggct ctcaagctgt aaacattatc aaccttcttg
     9001 gtggacgtgt aaacatcgtt gatgttgatg catgtatgac tcgtcttcgt gtaactgtta
     9061 aagatgcaga taaagtagga aatgcagagc aatggaaagc agaaggagct atgggtcttg
     9121 tgatgaaagg acaaggggtt caagctatct acggtccaaa agctgacatt ttgaaatctg
     9181 atatccaaga tatccttgat tcaggtgaaa tcattcctga aactcttcca agccaaatga
     9241 ctgaagcaca acaaaacact gttcacttca aagatcttac tgaggaagtt tactcagtag
     9301 cagacggtca agttgttgct ttggaacaag taaaggatcc agtatttgct caaaaaatga
     9361 tgggtgatgg atttgcagta gaacctgcaa atggaaacat tgtatctcca gtttcaggta
     9421 ctgtgtcaag catcttccca acaaaacatg cttttggtat tgtgacggaa gcaggtcttg
     9481 aagtattggt tcacattggt ttggacacag taagtcttga aggtaaacca tttacagttc
     9541 atgttgctga aggacaaaaa gttgcagcag gagatctcct tgtcacagct gacttggatg
     9601 ctatccgtgc agcaggacgt gaaacttcaa cagtagttgt cttcacaaat ggtgatgcaa
     9661 ttaaatcagt taaattagaa aaaacaggtt ctcttgcagc taaaacagca gttgctaaag
     9721 tagaattgta atatacttga ggttggaagc tgtattccaa cctcttattt tgggagaaaa
     9781 gaatgaaatt tttaacactc aatactcaca gttggatgga gaaagaagca gaggaaaaat
     9841 tccagatttt gcttgaagat attcttgaaa aggactatga tttgatttgt ttccaagaaa
     9901 tcaatcagga gatgacctcg tcagaggtgg aggttaatga cctttatcaa gctttgccag
     9961 cagctgagcc tattcaccaa gaccattatg ttagactctt ggttgaaaag ttgttagagc
    10021 aagggaaaaa ttactactgg acctgggctt ataaccatat cggctatgac cgctaccacg
    10081 aaggtgtggc tatcttgtct aaaacaccta ttgaagccag agaaattttg gtttcagatg
    10141 tggatgatcc aacagactat catactcgcc gtgttgccct agctgaaact gtagtcgatg
    10201 gcaaggagct agcagttgcc agtgttcatc tctcttggtg ggataaaggt ttccaagaag
    10261 aatgggcacg atttgaggct gtcttgaaaa aattgaacaa gccactttta ctagctggag
    10321 attttaacaa cccagcaggt caggaaggtt accaagctat tttagctagt ccattaggct
    10381 tacaagacgc atttgaagtt gctcaagaga aaagtggtag ctatactgtt ccgcctgaaa
    10441 ttgatggctg gaaagggaac actgaacccc ttcgaatcga ttatgtcttt actaccaaag
    10501 agttagcggt ggaaaattta catgtcgtat ttgatggtaa caagagtcca caagtgagtg
    10561 atcactatgg cttgaatgct atattaaact ggaaataata actgaaaaga ggttggaact
    10621 ataaaattcc agccttttct tactagagaa gctactggaa atagcctaaa taagtgagac
    10681 tactgtaatg gaataaaata tggtataatt gataaggtag atagaatcga ggatgttatg
    10741 tcatttacga aatttcaatt taaaaactat attagagaag ccttgaagga gttaaaattt
    10801 acaactccaa cagaggtgca agacaagttg attcctattg ttttggcagg tcgtgaccta
    10861 gtaggagaat caaaaacagg ttcaggtaag actcatactt tcttgttacc gattttccag
    10921 caattagatg aagctagcga tagtgtacaa gcagtgatta ctgcaccgag tcgtgagttg
    10981 gctactcaaa tttaccaagt agcgcgtcag atttcagctc actcagatgt cgaagttcgt
    11041 gtggttaatt atgtgggtgg tacggataag gctcgccaga ttgagaaatt ggcaagcaat
    11101 cagcctcata ttgttattgg aacaccaggc cgtatctacg acttggttaa atctggtgat
    11161 ttagctattc ataaagccaa gacatttgtt gttgatgaag cagatatgac cttggatatg
    11221 ggattcttgg aaactgttga taagattgct ggcagtcttc caaaagactt gcaattcatg
    11281 gtcttctcag cgactatccc acaaaaactg caaccattct tgaaaaaata cttatcaaat
    11341 cctgttatgg agaaaattaa gaccaaaacg gttatttctg acaccattga taattggttg
    11401 atttcgacca agggacatga taagaatgct caaatttacc agttgactca gttgatgcag
    11461 ccgtatttgg caatgatttt tgttaacact aaaacacgtg ctgatgaatt gcattcatat
    11521 ctgactgctc aaggcttgaa ggttgcaaaa atccatggag atattgcccc tcgtgaacgc
    11581 aagcgaatca tgaatcaggt gcaaaatctg gattttgagt atattgtcgc aacagatttg
    11641 gcagcgcgtg ggattgacat tgaaggtgtc agccatgtca tcaatgatgc cattccgcaa
    11701 gacttatctt tttttgttca tcgtgttggt cgtactggac gaaatggcct accaggtaca
    11761 gctattaccc tttatcagcc aagtgatgac tcggatatcc gtgagttgga gaaattggga
    11821 atcaagttta gtcctaagat ggtcaaagac ggggaatttc aagataccta tgaccgtgat
    11881 cgtcgtgcca accgtgagaa aaaacaagat aaacttgata tcgaaatgat tggtttggtt
    11941 aaaaagaaaa agaaaaaagt caaaccgggt tataagaaga aaattcaatg ggcggttgat
    12001 gaaaagcgcc gtaaaaccaa gcgtgctgaa aatcgcgctc gcggtcgtgc agagcgtaaa
    12061 gctaaacgcc aaacatttta atagaaattg ttggagtatt gagctccaac ttttttattt
    12121 atgagaacga actatctaaa ccgaaacact acattaaaga ctgcaaattg cgattaaaaa
    12181 tggtataatg ataaagttat atagtcccga taagatggta ggtatttatt acgaagagtt
    12241 ttcctatcag tactttgtaa ctctataaca atatttttta agggggggac atttttatgt
    12301 cagagcgtaa attattcacg tctgaatctg tatctgaggg gcatccggat aagattgcag
    12361 accaaatttc agatgcgatt ttggatgcta ttttagcaaa ggatccagag gcgcacgttg
    12421 ctgctgaaac agctgtatat actggttctg tccacgtttt tggtgaaatt tctacaaatg
    12481 cctatgtgga tattaaccgt gtggttcgtg ataccattgc agagattggt tataccaata
    12541 cagaatatgg attttctgct gagacggtgg gagtacaccc atctttggtg gaacaatctc
    12601 ctgacatcgc tcaaggtgtt aacgaagcct tggaggttcg tggaaatgct gatcaagatc
    12661 cactggactt gattggagca ggtgaccaag ggctcatgtt tggatttgca gtagatgaaa
    12721 cagaagagct catgccattg ccaattgcac tcagtcataa attggttcgt cgtctggcag
    12781 aacttcgtaa gtctgaagaa attagctatc tccgtccaga tgcaaaatca caagttacag
    12841 ttgagtacga tgaaaatgac cgtccggtac gtgtagatac agtcgttatt tctactcagc
    12901 atgatccaga ggccactaat gaacaaatcc atcaagatgt gattaaaaag gtcatcaaag
    12961 aagttattcc atcttcttat cttgatgata agacaaaatt ctttatcaat ccgacaggtc
    13021 gttttgtaat cggtggtcct caaggggact caggtttgac tggtcgtaag attattgtag
    13081 atacttatgg tggctactct cgtcatggtg gtggtgcctt ctctggtaaa gatgcgacta
    13141 aggtggatcg ttcagcctct tatgcggctc gctatattgc caagaatatc gttgcagcag
    13201 accttgctaa gaaggcagaa gtgcagttgg cctatgctat cggtgttgcg caacctgttt
    13261 ctgttcgtat cgatactttc ggtacaggaa cagtagctga aagtcaactt gaaaaagcgg
    13321 ctcgtcaaat ctttgacctt cgccctgcag ggattatcca aatgctggac ctcaagcgtc
    13381 caatttaccg tcaaacatcg gcttacggtc acatgggacg tacagatatt gatcttccat
    13441 gggaacgttt ggataaggta gatgctttga aagaagcagt aaaataagat tttaagaggg
    13501 gaacgtcctc tcttttttat agtttttaac tatactggga tactgttctg aaaatccatt
    13561 ttgtgaaagt agagatttac atgtatagta gattgaaact agaatagtac acctcaactt
    13621 ctaaaacatt gttagaaatc gatttgactg tcctgattga tttctcctgt tcttgtttca
    13681 ttttactata tttctttaaa aatgataaag gttgagattt ctcctcgtaa tagataatca
    13741 tggggatatt tcaatccaaa gttttattcg ttatcacttg actattgcaa ggttttctag
    13801 agcaacagag tcatggaatg gactcatggt tgagatttct ccttgttgct tggacttcat
    13861 tcaaaagtct gttacccaag ccttgttcaa acttccaata cactagctgt ttccatagca
    13921 tgacttctgt actagacttt cttttccgaa taaatagata gaaccacaga atctagtaaa
    13981 cctagaatta aaattatggt ataatattag caataaaaga aatctggagg attagaatca
    14041 tggtatcaac gaaaacacaa attgctggtt ttgagtttga caattgcttg atgaatgcag
    14101 caggtgtggc ttgtatgacg atagaggagt tagaagaggt caaaaactca gcggcaggaa
    14161 cctttgttac taagacagcg accttggact tccgtcaggg gaatcctgag ccacgctacc
    14221 aagatgttcc acttggttcc atcaactcta tgggcttgcc aaataatggc ttagactatt
    14281 atttggatta tcttttagat ttgcaggaaa aagagtcgaa ccgaactttc ttcttatctc
    14341 tggtcggcat gtctccagag gaaacccata ctattttgaa aaaagtccaa gagagtgatt
    14401 ttcgtggtct gactgagcta aatctttcct gtccaaatgt tccaggtaaa cctcagattg
    14461 cctatgattt tgagacaaca gaccggattt tggcagaagt gtttgcttac ttcaccaaac
    14521 ctcttggaat taaattgcca ccttattttg atattgttca ctttgatcaa gcggcagcta
    14581 ttttcaacaa atatccgctc aagtttgtca actgcgttaa ctctatcgga aacggcctct
    14641 atatagaaga cgaatctgtc gttattcggc ctaagaatgg ttttggtgga attggtggag
    14701 aatacatcaa accgactgct ctagccaatg ttcacgcctt ttatcaacgt ttaaatcctc
    14761 aaatccaaat tatcggaaca ggtggcgttc tgactggtcg agatgccttt gaacacatcc
    14821 tctgtggagc aagtatggtg caggtgggaa cgacccttca caaagaaggt gtcagtgctt
    14881 ttgaccgcat taccaatgaa ctgaaagcaa tcatggtgga aaaaggctac gagagcttag
    14941 aagatttccg tgggaaattg cgctatattg actaaattaa atcgaaaaat ctgaagaaag
    15001 gagagacgat gctagccatt gaagaaagtc agaagttgac tttatcaaat ttaccgagcc
    15061 tgagcctatt tacagggaca gatcagggtc agtttgaagt gatgaagagt caagtgttga
    15121 aacagattgg gtatgattct gctgacctca actttgccta ctttgatatg aaagaagtag
    15181 tttacaagga tgtggaactg gagttggtca gccttccttt ctttgcggat gagaaaatcg
    15241 tgatattaga ttattttatg gatatcacga ctgctaagaa acgctttttg acagatgatg
    15301 agcttaagtc atttgaggaa taccttgaca atccttctcc aacaaccaag ttgataatct
    15361 ttgcagaagg aaagctggat agcaaaagac ggttagtcaa attacttaag cgtgatgcca
    15421 aggtcttcga tgcagtagaa gtaaaagaac aagaattgcg ccagtatttc caaaagtgga
    15481 gtcagaaaca aggtctgcag tttaccaatc attcttttga aaatctcctc atcaagtcgg
    15541 ggtttcaatt tagcgaaatc cagaaaaatc ttctcttttt acagtcctat aaggcgaatt
    15601 ctgttatcga ggaagaggat attgttaacg caattcccaa gaccttgcag gacaatattt
    15661 ttgatttaac tcagtttatt ctgactaaaa agatggatca ggcgcgcgat ttggtgagag
    15721 acttgacctt gcaaggggaa gatgaaatca aactgattgc agtcatgctg ggacaatttc
    15781 ggacttttac tcaggtgaag attttggcgg agtctggcca aacagaatcg cagattgcaa
    15841 gtagtttagg tagttatctg ggacgtaacc caaatcctta tcaaatcaag tttgcattaa
    15901 gagattcgag aggactttct ttgagctttc tgaagcaagc tatttcctat ttgattgaga
    15961 cagactatca gattaagaca ggtctttatg aaaaaggttt cctttttgaa aaggcactct
    16021 tacagattgc tagtcaggtc aattgacatt tgttgaaact acaacccacg tcaggattat
    16081 cttgtcgtgg gtttcttgct gatttgctta ttttattaga aagtatgtca gtgatttcct
    16141 tatctataag caaaaaactt gaaaaaagtg aatgtttgcg ttatcatttt catatagaaa
    16201 gaaaaagagg tattacagat ggctattatc ttaccagaac ttccatatgc atacgacgct
    16261 ttggaaccat acatcgatgc ggaaacaatg catttgcacc atgacaaaca ccatcaaact
    16321 tatgtcaaca atgccaatgc agctttagaa aaacaccctg aaatcggtga agaccttgaa
    16381 gccttgcttg ctgatgtaga atctatccca gctgatatcc gtcaagcact tatcaacaat
    16441 ggtggcggac acttgaacca cgctcttttc tgggaattga tgactcccga gaaaacagct
    16501 ccttcagcag aactgacagc agcaatcgat gcaacatttg gttcatttga agaattccaa
    16561 gcagccttca ctgcagcagc aacaactcgt tttggttcag gttgggcatg gttggttgtc
    16621 aacaaagaag ggaaacttga agtgacttca acagcaaacc aagacacacc aatctcagaa
    16681 ggtaaaaaac caatcttggg cttggacgtt tgggaacatg cttactacgt gaaataccgc
    16741 aacgtgcgtc ctgactatat caaagctttc ttttcagtaa tcaactggaa taaagtagat
    16801 gaattgtacg cagctgctaa ataatgatag ttggagggaa gaattgttct tctctttttt
    16861 aggttataag attctggtct gacaaaatcg tcagactttt ttcattttta tgagaaacgt
    16921 gctaactgct agaaattatg gtagaataaa gtattaagta atcgtggaaa aaggatatct
    16981 atgcgaaaag aaattgcacc tgaattatac aactataaca agtttcctgg tccggagttc
    17041 catttacacg gggacaaggt cgaaacggaa gggatagctt tttccttggt tgaaaatatc
    17101 aaggatgcct ttgatgtgac gacttttaat cagcgttttt cagaagtatt aaccaagttt
    17161 gattatatcg tgggggactg gagcaacgaa cagcttcgcc tacgaggttt ttacaaggat
    17221 gaccgaacag aagaaaaact tgaaaaaatc agtcgtttac aagactacct tttagagtat
    17281 tgtagttatg gttgtgccta ttttgtctta gaaaatgaag cccctaagcg agcatcattt
    17341 gacaagaaaa tgcgtaagac ggaagaagaa acaccttcta gaaaaggaaa gaaaccgact
    17401 caaactaaac gaaagtcgaa tgcagataag aaaaatagac gtcgtcagaa agaccaacat
    17461 tctcagaaag aggacaagga acaacgtcat tttgtcattc gtcagaagtg agtagagaat
    17521 aaggagaaga aatgaaaccc tcaattcata gtttggcaca tcaaaccatg caggaatggg
    17581 tattggagca gggagaaaag aaattccgtg cagatcaaat ctgggaatgg ctctaccgta
    17641 aacgtgtgca gtcatttgaa gaaatgacca acctttccaa ggatttgatt gctaagctca
    17701 atgaccagtt tgtggtcaat cccttgaaac aacgtattgt gcaagagtct gctgatggta
    17761 cagtcaaata tctctttgaa ttgcccgacg gtatgttaat tgagactgta ctcatgcgtc
    17821 aacactatgg tttatctgtc tgtgtgacca ctcaggtcag ctgtaatatc ggttgtacct
    17881 tctgtgcctc tggtttgatt aagaagcagc gtgacctcaa taacggtgaa atcgtagcgc
    17941 aaatcatgct ggttcagaaa tactttgctg atgaaggggt tcaggtcaat cttgccgtgt
    18001 ctcttcacgc acccaacaat gaacttcgtt caagtatcat gaaaattaac cgtgcctttc
    18061 cgattgaaaa actctttgct gctattgaat actacattga gacaacaaac cgtcgtgtaa
    18121 cctttgaata tatcatgctt aatgaagtca acgacggtgt agaacaagcc ttggaattgg
    18181 ctgaattgct caagaacatc aagaaattgt cttatgtaaa cttgattcct tataacccag
    18241 ttagtgagca tgaccaatat agccgtagtc ccaaagagcg cgtgttggct ttctatgata
    18301 cgcttaagaa aaaagggggc aactgtgtgg ttcgtcaaga gcatggtaca gatattgacg
    18361 cagcttgtgg acaattgcgc tttaacacaa tgaaacgtga ccgccagaag gcagtcgcag
    18421 cggtaaatcc ttaatgatga agaagactta taatcatatt ttggtctggg gagtcatttt
    18481 ctatagcatt tgcattgtct atttttgctt tactcctcaa gaacaatcta ccgtgggagt
    18541 gggaactcca gatattcagc ctcttggacg cctggttttt cttttgactc ctttcaattc
    18601 tctctggaaa ctgggcgaag tgagtgacat tggacaatta tgttggattt ttttacaaaa
    18661 tatcctcaat gtcttcttgt tttttcctct gattttccaa ctcctttatc tatttccaaa
    18721 tttgcggaaa acaaaaaagg tccttctttt tagttttctt gtgagtcttg gaatcgagtg
    18781 tacgcaatta atcttggact ttttctttga ttttaatcgc gtctttgaga ttgatgattt
    18841 gtggaccaac actttgggtg gctatctggc ttggctcctt tataaacgat tacataaaaa
    18901 caagataagg aattaaaatg agtattttag aagttaaaaa tctgagtcac ggttttggtg
    18961 accgtgcaat ttttgaagat gtgtccttcc gtctcctcaa gggagaacat atcggcctgg
    19021 tcggtgccaa tggtgaagga aaatcaacct ttatgagtat cgtgactggt aaaatgctgc
    19081 cagatgaagg aaaggttgag tggtccaaat atgtgacggc tggttacttg gatcagcact
    19141 ctgtccttgc tgaaagacag tcggtgcgtg atgttctccg tacggctttt gatgagcttt
    19201 tcaaagctga agctcgtatc aatgacctct atatggaaat ggctgaagac ggtgcggatg
    19261 ttgatgctct catggaagaa gtgggagaac ttcaagaccg tctggagagt cgtgatttct
    19321 ataccttgga tgctaagatt gacgaagtag cgcgtgctct tggtattatg gactttggca
    19381 tggatacgga tgtaacttct ttgtcaggtg ggcaaagaac caaggtgctt ttggcaaaac
    19441 ttctccttga aaagcctgat attttgctgt tggacgagcc gaccaactac ttggatgctg
    19501 agcatattga ttggctcaag cgctatctcc aaaactatga gaatgccttt gtcctcattt
    19561 cgcacgatat tccattcctc aatgacgtta ttaatattgt ctatcatgtg gaaaatcaac
    19621 agctgacgcg ttactctggt gactactacc agttccaaga agtttatgct atgaagaaat
    19681 ctcagctaga ggcagcctac gaacgccagc agaaagagat tgcagacctc aaggactttg
    19741 tggctcgtaa taaagcccgt gttgcaactc gtaatatggc tatgtctcgt caaaagaaat
    19801 tggataagat ggatattatc gaactccaaa gtgagaaacc aaaaccatcc tttgatttca
    19861 aaccagctcg tacaccaggg cgctttatct tccaagccaa gaacttgcaa attggttacg
    19921 accgtcctct tactaagcct ttaaatctta ccttcgaacg caatcaaaag gttgcgatta
    19981 ttggtgctaa tggtattgga aaaacaactc tcttgaagag tctcttaggc attatctcgc
    20041 caatcgctgg ggaagtggag cgtggagatt atttagaact tggttatttt gagcaggaag
    20101 tagaaggcgg taatcgccaa actcctcttg aagctgtctg gaatgccttt cctgccctta
    20161 atcaagcaga agtccgtgca gcccttgccc gttgtggttt gacaaccaaa catattgaaa
    20221 gccagattca agtattatca gggggagagc aagccaaggt tcgtttctgt ctcttgatga
    20281 atcgtgaaaa caacgtttta gtgctggacg agccgaccaa ccatttggat gtggatgcaa
    20341 aggatgagct caaacgcgct ctcaaagaat ataggggatc tatccttatg gtctgccacg
    20401 agccagactt ttatgaaggc tggatagacc aaatatggga ttttaataat ttaacttaag
    20461 aatgagagta aaagaaatac agtaccgaat gtggatactg tatttttttg gtttttaaga
    20521 tttaaaatcg tagtctttca ccacttcgat gctgtcgatt gtgatagcag tagttggctt
    20581 gtctttttca tctttttcgg ccttagcaat cttatccaca acatccatac cgtcaatcac
    20641 ttgaccaaag actgggtgtt tgccatctag actagggttt ccaccttctt tgtaggcttc
    20701 gataattttc tgtggatact tgcttgtagg gagtttagaa gaggtatctg tagagttttg
    20761 gttgatgaag aactggctgc cattggtgtt tggttgacca gtattagcca tagcaagagc
    20821 accacggatg ttatacaaat aaggagtaat ctcgttcttg aaaccagttc ctttgtcttt
    20881 agtcttatcc ttgtcatgcc agatggactg accacctgta ccgtcccctt ttggatctcc
    20941 agtttggacc ataaagccat cgatgacacg gtggaaggta ataccgttat agtagccttc
    21001 tttggcgtga gtgaggaaat tttcaaccgc tagaggagcg agtttaggga agagtttaat
    21061 gcgaatatca ccttggcttg tgtggagaat cacttcggct tcatcttcag caacttcctt
    21121 agatagttgt gggaaattgg cgttttcgtt tgttaaagca tcgtttaact ccttggcaga
    21181 ttgggcagct actttggaac tttcttcagc agcaagactg gaatcaacat aatcatcacc
    21241 acgcagactg cgttggacgc tgctacaccc agctagggct acagtagaca gtaaaagaag
    21301 ggttgctagt tttttcattc tgatcctctc aaaaattcat ttataaccat tgtaccctaa
    21361 aaggaagtgg atttcaaata ttagtagttt acagaactgg cttagataat agttgggatt
    21421 tcatcatcat cttgaaaatc ttcaacttct tccccagtaa atggtttctg aaaagaactt
    21481 agtataaaac gggcaattgg ttcaacaatt aggaaattta gaggaagagc tgcaataaag
    21541 tttacgaacc aggcgcttag ataggtattg ggtgtgatag caatgccatt gtaaaaaaag
    21601 tccatagaag gacatgaaag tgaccagcta attcttcttc tgaaaaatgc tcatgaaggg
    21661 cttgatccag gtcgcaagat ttcattttag aaagtccagt aactcccttc ttcttcagga
    21721 tattcttttt catggtagta tttagatggt caagtgagtc aaaagaagtt tcgacaagag
    21781 catacccttt ttctaccaga gtttttagat gtttaggggc atcaatacca taagtgtact
    21841 caaagtattt tggaaaccag atcttaagaa agctcgtaaa gctagccagt tctctaaacg
    21901 ctaagaacta gctacaacac agcatttaca acacttcatg gttcacacca tggggtgttt
    21961 tttaatgatt ttaagcaaaa ttcacactta attgaaagtt atttaaatta gatgaaaatt
    22021 tattttttga aaaagtggga aaacattgat tctaagcgaa ttttgaatca tattcgaatg
    22081 ggagttttta aaatcatgtt tcagtggtaa aagtaccaaa ctggattctc catagtaaaa
    22141 tgatatctcc tgctagtgaa tcatctacta ataagtccat atttcgcttg ggaacgggct
    22201 tgggacttag aagccaagta tccaactctc gttcaggcga tatgaagggt ttgacttggt
    22261 gttctttata aaatttttct aaaatagtat tcacggatag catctttcaa acatttattt
    22321 cctattctaa caaatttcta aatactttaa gaaatttata gtctgtcaag tttttttctt
    22381 gacacatgtc agaaatctgc tataatagaa catgtgctaa atagctcagc tatttcaccg
    22441 aaataaaaaa ttaaagaaat gagactttaa aaatggcagt taaaatccgt ttgactcgta
    22501 tgggttctaa gaaaaaacct ttctaccgta tcaacgtagc agattcacgt tcaccacgtg
    22561 acggacgttt catcgaaaca gttggaactt acaacccact tgttgctgaa aaccaagtaa
    22621 ctttgaaaga agaccgcgtt cttgcatggt tggctaatgg agctcaacct tcagacacag
    22681 tacgtaacat cctttcaaaa gaaggcgtat tgaaaaaatt ccacgattct aaattttcaa
    22741 aataagttta aagtaggttg acagatggat acgattgaaa atctcattat tgcgattgtg
    22801 aaacccttaa tttcacaacc agatgcctta actatcaaga ttgaggatac accagaattt
    22861 ttggaatatc atttgaatct tgatcaaagc gatgtgggtc gtgtaatcgg tcgtaagggt
    22921 cgcactattt ctgcgataag aacgattgtc tactctgtcc caactgaata caaaaaagta
    22981 agaatcgtta ttgacgaaaa ataagaaggg cgggacggat gtctcgcttt tttgtgtgga
    23041 atagaagata tagtaaaatg aaacaagaac aggacaaatc gatcaggaca gtcaaatcga
    23101 tttctaacaa tgttttagaa gtaaaggtgt actattctag tttcaatata ctataaaaga
    23161 ttgaacgttt aggcaattcc aagactactt aatcgaacat taacagcagt ctcggactga
    23221 tgaaggtctc tttatgaagt tagtggagga agtcggaaaa gtagccgagg ttttgaatag
    23281 gcgctctggt cgaaaagaag ggataggatt cgaacgagga acttgccaga gaactggctg
    23341 atatcattta ctacaccgtc gcaatcgtag ctattaatca tattgacctt accaagactg
    23401 tctttgagaa agacaaaacc gcagccgtta attaccaaca taaacataat ttggaaggat
    23461 tattgaaggg aaagtagaga tgttgtcccc ttcctccaac ttgagaaaat ccttggaacg
    23521 tgataaaata aaggataatg atttttaata attcattata tagaatgagt ggatttcttt
    23581 atgaagaggt ttgaagtatc tacagaaatt ggtagcctct ctgttactta tcaaaagcaa
    23641 aagaaagtgc tagtttgtct aaacggagca ggtttgctac caagttatga aaatttttca
    23701 cttatacttg aaaaacctcc tcctacaatt ggttatttga caattgattt tccgaacaca
    23761 ggtaggagtc cgattcatga ccaagctgga aaaaatctag ataatcttgc agatgcggtt
    23821 tatgaagtac ttgaagaatt aggaatttct gaatatatac tttgtgcaca tagttggagt
    23881 ggaattttag cttgcaaatt actcgagaaa ccaattaagc gtcagacttt agtagcaatt
    23941 gaaccgacaa ctaaaaaagt catgtttgct gatttttcag aaaatcctta tccaaaaatg
    24001 gaagagcaga tgaggctgat tgacgagtgt ggtcctgaac tttattttaa gaacttaact
    24061 caagcaacat ttagtcctga aacgaataaa aaaatctggg aattaatgca agaaaaaggc
    24121 ttagagttgg aaaatcaaga tccagaattt cagatatctg gagagattac tgaggaagat
    24181 tttgagaatt tgtcgataga atctcatgtc cctgttttta ttttttgtca gacttataga
    24241 gaaaaagagt acagagaatc agaatattgg acttccaata ctaaactcat tttaggaggg
    24301 aatcaccatt atttacaatg gtcagaatcg gaaaaaattg cggctattat tcgagaattg
    24361 tcagaataag atggaaaaaa ggagattaca ggagacaaga tgaactactt taatattggg
    24421 aaaatcgtta atacgcaggg attacagggt gagatgcgag tcttgtctgt gacggatttt
    24481 gcagaagaac ggtttaaaaa aggagctgag ctggctttgt ttgatgaaaa agatcagttt
    24541 gtccaaacag tgaccatcgc tagccaccgt aaacagaaga actttgacat tattaaattc
    24601 aaagatatgt accatatcaa tactatcgaa aagtacaagg gatacagtct caaggtcgct
    24661 gaggaagatt tgaatgacct agacgatggt gaattttact atcacgagat tatcggtttg
    24721 gaagtctatg agggtgatag cttggttgga accatcaagg aaatcctgca accaggtgct
    24781 aatgatgtct gggtggtcaa acgaaaaggc aaacgtgatt tgcttttacc ttatatccca
    24841 ccagtggttc tcaatgttga tattccaaat aaacgggtcg atgtggaaat cttagaaggg
    24901 ttagacgatg aagattgata ttttaaccct ctttccagag atgttttctc cactggagca
    24961 ctcaatcgtt ggaaaggctc gagaaaaagg gctcttggat atccagtatc ataattttcg
    25021 agaaaatgct gaaaaggccc gtcatgtaga tgatgatccc tacggaggcg gtcagggcat
    25081 gttgctcaga gcacaaccta ttttcgattc ctttgatgct attgaaaaga aaaatccgcg
    25141 cgttattctc cttgatcctg ctggaaagca gtttgatcag gcttatgctg aagatttggc
    25201 tcaagaggaa gagctaatct ttatctgtgg gcactatgag ggttatgatg agcgcattaa
    25261 gaccttggta acagatgaga tttccctagg cgactatgtc ctcactggtg gagaattggc
    25321 agctatgacc atgattgatg ctacagttcg cctgattcca gaagtgattg gcaaggagtc
    25381 tagccaccaa gatgatagtt tttcttcagg tcttttagaa tatcctcagt acacacgtcc
    25441 ctatgattat cgaggcatgg tcgtgccaga tgtattgatg agtggccacc atgaaaagat
    25501 tcgtcagtgg cgattgtacg agagtttaaa gaaaacctac gagcgcagac cggatttact
    25561 tgaacattat caactgacag tagaagaaga aaaaatgctg gcagaaatca aagaaaacaa
    25621 agaataaagg agaaacctat gcaagtaatc aaacgtaatg gcgaaattgc tgaatttaat
    25681 ccagataaga tttaccaagc catcttgaag gcagcccaaa ctgtttatgt tttgacagat
    25741 gatttgcgtc aaaatcttgc tcaagtcact aagaaggtag ttttggattt acaagaagcc
    25801 aaggtggaac gtgcgactat cagtatgatt caatctatgg ttgaacatcg tttattgggc
    25861 gcaggttaca ttaccattgc agaacactac atttcctatc gtttacaacg tgacttggaa
    25921 agaagtggtt atggagatca tatcgcagtt catttacatt ttgaacaaat tcgctaagaa
    25981 aaaagagtgg gatgaagcaa ctacatctca ctctttctta aatctatttt tttgggctgt
    26041 ttggacagtt gaggggacaa atcgcaggcg ttgaatatcg cttatacgga taatccggct
    26101 cacatttttg gcaaaatttt tcacgataat ttgctggcct tgctgatcat atttgatgat
    26161 atcacctgta aagcttgtct cagacaagat aaggtgaaca gcggtttgtt tctggatagc
    26221 ctcttcaata gtggctgtaa gggagttggt ttcagtctgg tcaggttggt catgtccatt
    26281 taaaaaatca tgtattttat ctagaacttg ctggaattta tgtctcatat tggcctccct
    26341 tcttctatat caatattata taaaattttc ctaaaatcta caagatttta cgaataaact
    26401 aatgaaacta aaaaaggaga agaaaatggc agaatttaca tttgaaatcg aagagcactt
    26461 gttgactctt tctgaaaacg aaaaaggttg gaccaaggaa attaaccgtg tgagctttaa
    26521 tggtgcccct gcaaagtttg atattcgtgc ttggagtcca gaccatacta aaatgggcaa
    26581 agggattact ctctcaaatg aagaatttca aacgatggtg gatgccttta aaggcaacta
    26641 atactcttcg aaaatctctt caaaccgcat cagctttgcc ttgccgtatg tatggttact
    26701 gacttcgtca gtttcatcca caacctcaaa acagtgtttt gagcagcctg cggctagctt
    26761 cctagtttgc tctttgattt tcattgagta taagttttca aaataaaaaa aaaggatatt
    26821 gagtcatgat aactcgatat ccttttttag ttagtaaagt aagcctgatt tttaaggcgt
    26881 tgaagtaggg gacggctaat aaaactaata gccagaagtt tgccaaggtc tggaatgata
    26941 aagggaagaa cccccacaac aagagctttt tcaaatgcca ttccagctag gaaatgcaag
    27001 ctgagaatcc cgccgacaaa gacaagggca tcacccaaga ggtttgcaag aaaaatctta
    27061 acaacaccac tcttgctgtt ggttagagag gaagtaagtc cagagtaaac gagataaaac
    27121 caaagatagc ctgcagtagg gccaactaaa gcctgaaaac cagctccacc tcctgcaaag
    27181 acaggaagac cgatagcacc tagaagaaga tagagtccag cagaaagtac agcctctctc
    27241 ggtctaaaga cagtagcaat caagccgatt gcaaagtttt gcagagtgaa gggaacaggt
    27301 ccaattggaa gactgatttg tgccaaaaca gcaatgagag cagccccaat agcagggata
    27361 gcataaacgt gagctttttt caaaatagtt aacctctttt ctaatgtata gtaactatta
    27421 tactcatata ggagtcgatg tcaaccattt tttaaaaaca aggtaacaaa aactgtaaca
    27481 gccgattttc gtgactagtc aagttggata atttttttgt tgattcgaaa attgtctgta
    27541 tagataatcc tattttatta ataaaaaata tactagtaaa tacttgacaa attaaaaaat
    27601 aagtgttaca ttaaaaatgt aaacggatac atttagatgt gttcaatttt aaaaggaggg
    27661 gtagttatga gatattttaa cgactctaga taccataacg gtgattaaaa acctaaatat
    27721 aatcaattca tattaaagta atatggaggg actaaaaaga gactattatt taatcttcat
    27781 caaatattta aattcaagga gaagtaaaat gaaaaaaaga attaataaga aagcatctgt
    27841 ttttctagtt gcaagtgttt tcagttttag ctttgctact acagctagtg tcgttaacgc
    27901 agtaacggca caccctgctc caagtcccat tattgatgta tgggaatatg gtgtaaatga
    27961 taactatggt tattcgaatt actttgttag ttctccaagt aatattggat caaaatcttc
    28021 agtaacgaat ttttggggaa cagttaaagc tcaggataaa aaagattatg gatgggcata
    28081 ttcaagtgca acaaaatctt ggaacgatgt tcgcttaaat gcatattggg attattatag
    28141 attttaaaaa taatttatga aaacaagaga cccaattata agattgggtc tcttgtaata
    28201 tggtaattgc ttatgaaatt aaaattatgt atcattggat tcttcttttg tttgattgct
    28261 acaattggtc tggtcactat tagtgatacc gaaatcccca tacctttacc aattgatgga
    28321 gctttttcta tccaaggaaa aagtaatctt tctaataacg aaatatacga aatggttcgt
    28381 gacttatcaa aaacggaaaa ggttaccatt tacaagccaa tcgttcagag ttcgggtcag
    28441 ttgaagtatg taaattttga tgatgtaaat aatgaacaat taaagtcagc accaatagta
    28501 gggatgtatt acacacttgg gaaaatggat gtagacagtt tgaaaccact tacgatgacg
    28561 ggactacaaa cagtctatat ggcttatcct tggtatatag gaggaatatt acaattcact
    28621 ggaactttaa gaatactgtt aatgggttca atttatttaa ctttattagt tgttttattt
    28681 gttgttagga cgaggcagat caaagaagga gtgatacgac gttctttggg cttgcctata
    28741 tacgacttaa gaagagagta tggcatttct cttatttttg aactgattat gatggcttta
    28801 ttgatgattt cttacagttc ttttttgggt aatggtttct tcacctatag ttctaagtta
    28861 tttttctctc tgcttttaac gaattttata ctatttcaaa tcattgatct tattactttt
    28921 gttttatttt ggttgacgat tcagattgaa aagcctattg aaattattaa aaacaaggca
    28981 aaaaacaagc ttatttttgt cgtatggctt gctattattt cgattatcat ccttgtctca
    29041 ggagtttttt tacaagaaac aaagagtagt caatctagta ttaacataca gatacagaat
    29101 ttagtaccat gggatacagt aaaagactgg agaaggattg agttccttgg aattgaaagt
    29161 aactctacta aaaatagaga agttaatgat tcagatggtc agtatctaca gatagttgct
    29221 gccttaaaaa acttagattt cttatatata gaacggtctt cagcatatgt tccagatttc
    29281 atgaaaactt cacatgttat agaaaatttt tctaaacaat tagaaaatga cgggataacg
    29341 aatccagaaa taaataaaga gttaatttat atcaaccaaa caggtgctaa cctacaaaat
    29401 aaagtgaatg gaacaaacta tcatctttta gataataaga tagcaaccat ctatattcct
    29461 gagaagtgga aagaaaacca gaaatctatt gagaatacag ttgtagcaga acaatttatt
    29521 ggaacaaact atacaagaga acagcttgca gttcaaataa ttcctgatgg ggaaaaaatt
    29581 ttttatttta atgaggatgc tgataataat cttaaaatga aagatatttt accgctggca
    29641 aatgtagcag atagcaaaga taatatagtt gttgtgttag atacggacaa aatgatggaa
    29701 aataataagt tttctttggc tagtaacata ctatataaat ctctttttag tcctgaagcg
    29761 gtaaaaaaaa taaatgagat gactgtcctg ttgaatttct caatgaatcc agtagatgtt
    29821 taccaaattg tgaaattaaa gattcaatcc ttagagcacc aaattttact ttcacaaatc
    29881 ttgcagaaga taatttacag tattgtcttt atactcattt atcaatatgt ccaacttttt
    29941 attactctaa aacagaatga atatgtgaaa aaaatcattt tgggtctgtc aaaaacatat
    30001 atagcaattt caagtctcaa atattttatg atgactatta caatggttat tctatttaca
    30061 tttcttatga cagggcaaat agagttgcta tatattggag cggcttctct gctagttttg
    30121 atgttgtcaa tcataatgag ttttagaaaa ttatctgaaa gctacactaa aattttaaaa
    30181 ggagatgaat catgacaatt gaccttttga acgtttcaaa aagtttcggc tcaaagaaga
    30241 tctttacaga cttaaattta atatttgaat ctggaaaaag ctatgcattg attggaggtt
    30301 ctggctccgg taaaagtacc cttcttaata ttataggaag attagaaaaa attgacagtg
    30361 ggaatgtttt agttgataaa caagatattt ggaagataaa agaaagaact ttttttaaaa
    30421 atactgttgg atatgtattt cagaattatt ctttaataga taacaaaaca gtgtatgata
    30481 atctgagcct tatcactaaa gacaaaaaaa caataactga cgtacttgaa aaagtaggac
    30541 tgtcaagtga ctatttacac caaaaaatat atgaattgtc tggagggcag gctcaacgtg
    30601 tagctattgc cagaatgtta atgaaaccac gtaaaattat cttagcagat gaacctacag
    30661 gagctttaga tggtgagatt ggaaaagaaa ttattcgttt actattgaat gaaacagctg
    30721 aagataaata tgtcattata gcgacacatg atccagctgt ctataacgaa gttgatgtga
    30781 taattgacat gaaagatata gggtataagg tatgaaaaag aaaatttata ttgctttgat
    30841 ctttgtaact ggggtactcg ccattttctt ttttggaaaa caaatgatta caaaagaaaa
    30901 tatcaataag ccaacggtag agttaacaat ctatacgctt tcttctagtg atacagaaaa
    30961 atggaataaa gtgagacaag tagaaacgga agaagctata tacttcataa ctgtgaaaga
    31021 agtatcatct tcagaagaag tattttcaaa catcattgca aatggagctg ctacggggtt
    31081 cggagttcgt gaagaagaag tgaagaaatt caataatggt ttaggagaca ccatagagga
    31141 ctctaagcat aataaactaa ttgaaataga attttttact ttttctgatg atggcgcggg
    31201 atttgtggta gcaaactttg actacggtaa agaagagttg aattctcaga aaaaagatat
    31261 aaaagaatta tataaaaaaa tatatgaatc ttttaaagaa aagaataaat gattgtatta
    31321 taatccttgt attttgctat ggtttgttaa ttgatttttg catatcttac ttcaacatac
    31381 tataaaataa aacataagaa aacgagtatc tccaactacg gaaatactcg ctttttgata
    31441 tttagaagtg ttttttgctt tgcttctttt gtttcgatta acgcatggtt acaaattctt
    31501 cagatgcagt tgggtgaatt gccacagttg catcaaagtc agccttggtt gctcccattt
    31561 tgatagcaac ggcaaatcct tgaatcattt catcaacgcc gtagccaatt ccatgaagtc
    31621 cgacaacttt ttcttctgaa ccagctgtta tgagtttgaa acgggattct tgacggttgc
    31681 gagtgcaagc agagtacata gatgcaaagc ttgatttata aaccttgatt tggtcttgac
    31741 cgtattcttt aatagcttgc tcttctgtca aaccaacagt tccgatagca gggtgtgaaa
    31801 agacaacagt tggaatagtt gagtaatcca tttttgcagt agtttttccg ttaaagagac
    31861 gttcagatag ggtacgtccg gccttgattg caactggagt cagttctttc tcgcccgtta
    31921 catcacctag agcatagatt ccctcaacaa cagtattttg gtattcatcc acttggataa
    31981 agccacgttc gttcagagtc actccagctt tttcaagttg caagccctta acgtttggac
    32041 ggcgacctgt agcccagata acttggctag ctgtgtgact agtaccatct tcgaaatgaa
    32101 tggtaatgcc gtcagtagtt ttttctaact tgacagggac tttgtgagtg tgaagtggta
    32161 agtttgttct ttccatttcc ttgaccaaac cttcaacgat gtaggaatca aaaccacgta
    32221 aaggacgatc gcggcgaaca aagagatctg tcttgacacc aaaagtgtgg agtacgccag
    32281 ctaattcaac ggcgatataa ccagcgccta gaatggcaat tgactctgga agttcttccc
    32341 aggcaaatac atcatcagaa gagccaccta gctcagcacc aggaatatta ggaatacttg
    32401 gatgggcacc tgtagcaatc acgatatgtt tagcacgaat cagttcacca tttacgctta
    32461 cagtatgaga atctacaaat tcagcatgac cttcaatcaa gtctacaccg ttgcgtttaa
    32521 aactaccatc ataagaagaa cgagcgcgat caatgtaggc ttcacgattg cgacgtaggg
    32581 ttgcaaagtc aaagttaaga tcagtagtct taaagccgta gtcttctcca aattgatgga
    32641 aagtctcagc gatttgcgcc ccgtaccaca tgattttttt aggaacacaa ccgacgttga
    32701 cacaggttcc acctaatttc ttttcctcaa taacggctgc tttggctcca tgttcaccag
    32761 cacggttcat ggtagcgatt cctccgctac ctccaccgat agcaatgata tcatattctc
    32821 tcattgaaaa ctcctttgta atcttttaaa tagtagagcg tcttttttga tagttatatt
    32881 ttattctttt tttgatttga ttgcaaaaat ctgctacgca caaaaaattg caaaaaagct
    32941 tgccaaataa gtcaagatag tgtattatat atctagtaca atagaaaagc aaaattccga
    33001 acgattgttt aatcctgaac tgtattgttt gctggaggga aatttggtat aatagcaaag
    33061 tattgtaaaa aagaaaagga gtttcattat gaagaaaaag aatggtaaag ctaaaaagtg
    33121 gcaactgtat gcagcaatcg gtgctgcgag tgtagttgta ttgggtgctg gggggatttt
    33181 actctttaga caaccttctc agactgctct aaaagatgag cctactcatc ttgttgttgc
    33241 caaggaagga agcgtggcct cctctgtttt attgtcaggg acagtaacag caaaaaatga
    33301 acaatatgtt tattttgatg ctagtaaggg tgatttagat gaaatccttg tttctgtggg
    33361 cgataaggtc agcgaagggc aggctttagt caagtacagt agttcagaag cgcaggcggc
    33421 ctatgattca gctagtcgag cagtagctaa ggcagatcgt catatcaatg aactcaatca
    33481 agcacgaaat gaagccgctt cagctccggc tccacagtta ccagcgccag taggaggaga
    33541 agatgcaacg gtgcaaagcc caactccagt ggctggaaat tctgttgctt ctattgacgc
    33601 tcaattgggt gatgcccgtg atgcgcgtgc agatgctgca gcgcaattaa gcaaggctca
    33661 aagtcaattg gatgcaacaa ctgttctcag taccctagag ggaactgtag tcgaagtcaa
    33721 tagcaatgtt tctaaatctc caacaggggc gagccaagtt atggttcata ttgtcagcaa
    33781 tgaaaattta caagtcaagg gagaattgtc tgagtacaat ctagccaacc tttctgtagg
    33841 tcaagaagta agctttactt ctaaagtgta tcctgataaa aaatggactg ggaaattaag
    33901 ctatatttct gactatccta aaaacaatgg tgaagcagct agtccagcag ccgggaataa
    33961 tacaggttct aaataccctt atactattga tgtgacaggc gaggttggtg atttgaaaca
    34021 gggtttttct gtcaacattg aggttaaaag caaaactaag gctattcttg ttcctgttag
    34081 cagtctagta atggatgata gtaaaaatta tgtctggatt gtggatgaac aacaaaaggc
    34141 taaaaaagtt gaggtttcat tgggaaatgc tgacgcagaa aatcaagaaa tcacttctgg
    34201 tttaacgaat ggtgctaagg tcatcagtaa tccaacatct tccttggaag aaggaaaaga
    34261 ggtgaaggct gatgaagcaa ctaattagtc taaaaaatat cttcagaagc taccgtaatg
    34321 gtgaccaaga actgcaggtt ctcaaaaata tcaatctaga agtgaatgag ggtgaatttg
    34381 tagccatcat gggaccatct gggtctggta agtccactct gatgaatacg attggcatgt
    34441 tggatacacc aaccagtgga gaatattatc ttgaaggtca agaagtggct gggcttggtg
    34501 aaaaacaact ggctaaggtc cgtaaccaac aaatcggttt tgtctttcag cagttctttc
    34561 ttctatcgaa gctcaatgct ctgcaaaatg tagaattgcc cttgatttac gcaggagttt
    34621 cgtcttcaaa acgtcgcaag ttggctgagg aatatttaga caaggttgaa ttgacagaac
    34681 gtagtcacca tttaccttca gaattatctg gtggtcaaaa gcaacgtgta gccattgcgc
    34741 gtgccttggt aaacaatcct tctattatcc tagcggatga accgacagga gccttggata
    34801 ccaaaacagg taaccaaatt atgcaattat tggttgattt gaataaagaa ggaaaaacca
    34861 ttatcatggt aacgcatgag cctgagattg ctgcctatgc taaacgtcag attgtcattc
    34921 gggatggggt catttcgtct gacagtgctc agttaggaaa ggaggaaaac taagatgcag
    34981 aatctgaaat ttgccttttc atctatcatg gctcacaaga tgcgttcttt gcttactatg
    35041 attgggatta ttatcggtgt ttcatcagtt gttgtgatta tggctttggg tgattcccta
    35101 tctcgtcaag tcaataaaga tatgactaaa tctcagaaaa atattagcgt ctttttctct
    35161 cctaaaaaaa gtaaagatgg ttcttttact cagaaacaat catcttttac ggtttctgga
    35221 aaggaagagg aaattcctgt tgaaccgcca aaaccgcaag aatcctgggt ccaagaggca
    35281 gctaaactga agggagtgga tagttactat gtaaccaatt caacgaatgc catcttgacc
    35341 tatcaagata aaaaggttga gaatgctaat ttgacaggtg gaaacagaac ttacatggac
    35401 gctgttaaga atgaaattat tgcaggtcgt agtctgagag agcaagattt caaagagttt
    35461 gcaagtgtta ttttgctaga tgaggaattg tccattagtt tatttgaatc tcctcaagag
    35521 gctattaaca aggttgtaga agtcaatgga tttagttacc gggtcattgg ggtttatact
    35581 agtccggagg ctaaaaggtc aaaaatatat gggtttggtg gcttgcctat tactaccaat
    35641 atctcccttg ctgcgaattt taatatagat gaaatagcta gtattgtctt tcgagtgaat
    35701 gataccagtt taaccccaac tctgggtcca gaactggcac gaaaaatgac agagcttgca
    35761 ggcttacaac agggagaata ccaggtggca gatgagtccg ttgtatttgc agaaattcaa
    35821 caatcgttta gttttatgac gacgattatt agttccatcg cagggatttc tctctttgtt
    35881 ggaggaactg gtgtcatgaa catcatgctg gtttcggtga cagagcgcac tcgtgagatt
    35941 ggtcttcgta aggctttggg cgcaacacgt gccaatattt taattcagtt tttgattgaa
    36001 tccatgattt tgaccttgtt aggtggctta attggcttga caattgcaag tggtttaact
    36061 gccttagcag gtttgttact gcaaggttta atagaaggta tagaagttgg agtatcaatc
    36121 ccagttgccc tatttagtct tgcagtttcg gctagtgttg gtatgatttt tggagtcttg
    36181 ccagccaaca aggcatcgaa acttgatcca attgaagccc ttcgttatga atgagatcaa
    36241 caagatggac actcgtctat cttgtttttg tatggatttc cctatcgaaa ttcattaaaa
    36301 atgtgatata atgaagtgtt agaaaaacag gtttcatttg cctggaaagg aaaaattatg
    36361 tctgaaaaaa atttttatat tacaacgccg atttactatc catctgggaa acttcatatc
    36421 ggttctgcct acacaactat cgcatgtgat gtcctagcac gttacaaacg cctgatgggc
    36481 tacgatgtat tttatctgac aggtcttgat gaacatggtc agaaaatcca gcagaaagcg
    36541 gaagaagctg gtattacacc tcaagcctat gttgatggaa tggcggttgg agttaaagaa
    36601 ctctggcaat tactagatat ctcatacgat aaatttatcc gtacaactga tgactaccat
    36661 gaaaaagttg tcgcacaagt ctttgaacgc ttacttgctc aagatgatat ctacttgggt
    36721 gaatactctg gttggtattc agtatcagac gaagaattct ttacagaaag ccagctggca
    36781 gaagttttcc gtgatgaagc tggaaatgtg actggtggta ttgctccatc aggtcatgag
    36841 gttgaatggg tttctgaaga atcatacttc cttcgcctta gcaaatacca agaccgtttg
    36901 gtcgaatttt tcaaagctca tcctgaattt atcacgccag atggtcgcct taatgaaatg
    36961 ctacgcaact tcatcgagcc aggtttggaa gatttggcgg tatctcgtac aacctttaca
    37021 tggggagtgc ctgtcccatc aaatccaaaa cacgttgtct acgtttggat tgatgccctt
    37081 cttaactatg cgacagctct tggctacgct caagacgaac atggtaactt tgacaagttc
    37141 tggaatggaa cagtcttcca tatggtagga aaagatatcc ttcgcttcca ctctatctac
    37201 tggccaatcc ttcttatgat gttggatgtt aaattacctg atcgtttgat tgcccatggt
    37261 tggtttgtca tgaaagacgg aaaaatgtct aagtcaaaag ggaatgtcgt ttaccctgaa
    37321 atgttggtag agcgttatgg actagatcca cttcgttact acctcatgcg taaccttcca
    37381 gttggttcag acggaacctt tactcctgaa gactatgtcg gccgtatcaa ctatgaattg
    37441 gctaatgacc ttgggaacct ccttaaccgt acggtttcca tgattaataa gtactttgat
    37501 ggacaaatcc ctgcctatgt agaaggtgtg actgaatttg atcatgttct tgctgaggtt
    37561 gcagaacaat caatcgcaga cttccataca cacatggaag cagttgacta tccacgtgcg
    37621 cttgaagcag tctggactct gatctctcgt accaataaat acatcgatga gactgcacca
    37681 tgggtcttgg ccaaggatga agctcttcgt gaccaattgg caagtgtcat gagccacttg
    37741 gcagccagca ttcgtgtagt tgctcacttg attgaaccat ttatgatgga aactagtcgt
    37801 gcagttttga ctcaacttgg tttggaagaa gtttctagtc ttgaaaactt gagtttggct
    37861 gacttcccag cagatgtgac tgtagttgcc aaaggaacac ctatctttcc acgtctaaat
    37921 atggaagaag aaatcgccta tatcaaggaa caaatggaag gcaataaacc agcagtcgaa
    37981 aaagaatgga atccggacga agttgagctc aaactaaaca aggatgaaat caagtttgaa
    38041 gactttgaca aggttgaaat ccgtgtcgca gaagtcaaag aagtgtctaa agtagaaggt
    38101 tcagataagt tgcttcaatt ccgcttggat gctggtgatg gagaagatcg tcagattctt
    38161 tcaggaattg caaaatacta tccaaatgaa caagaattgg tcggcaagaa agttcaaatc
    38221 attgctaacc tcaaaccacg taaaatgatg aaaaaatatg tcagccaggg tatgattctc
    38281 tcagctgaac atgatggcaa attaaccctt ctcacagttg atccagctgt accaaatgga
    38341 agtgtgattg ggtaaaagta gacaggacta gttcaggcta gttctgtttt tttatttata
    38401 ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggttgctcaa aacacagttt
    38461 tgaggttgta gatgaaactg acgaagtcag ctcaaaacac agttttgagg ttgtagatga
    38521 aactgacgaa gtcagtaacc atacataagg tagggcgacg ctgacgtggt ttgaagagat
    38581 tttcgaagag tattaactat tatgctttac aaactagtgt agaagtgata tactataggt
    38641 gaagttacta gtaggtatta caaaatagat tagaagggaa aagtgatgaa agaaactcag
    38701 ctattaaaag gtgttcttga aggttgtgtc ttggatatga ttggtcaaaa agagcggtat
    38761 ggttatgagt tggttcagac tttgcgagag gctggatttg atactatcgt tccaggaact
    38821 atttatcctt tgttgcaaaa gttagaaaaa aatcaatgga taagaggcga catgcgcccg
    38881 tcgccagatg gtccagatcg gaagtatttt tcattaatga aagaaggaga agagcgtgtc
    38941 tcagtctttt ggcaacaatg ggacgatttg agtcaaaaag tagaagggat taagaatggg
    39001 ggttaaacca tgaagaaaat gaagtattac gaagaaacaa gcgctttgct acatgagttt
    39061 tctgaggaga atcaaaagta ttttgaggag ttgtgggaaa gttttaatct tgctggattt
    39121 ctctatgatg aagactatct cagagagcag atctatttga tgatgctaga tttctcagaa
    39181 gcagaacgag atggcatgag tgcagaggat tatctaggta agaatcctaa aaaaataatg
    39241 aaagagattc tcaagggagc acctcgcagt tctatcaaag agtccctttt gacgccaatt
    39301 cttgtcctgg cggtattacg ttattatcaa ctactaagtg atttttctaa aggtcctcta
    39361 ttaacagtca atttgctcac atttttaggg caacttctta tttttctgat tggatttgga
    39421 cttgtggcca caattttacg aagaagttta gtccaagatt ctcctaaaat gaaaattggc
    39481 acttacattg ttgttgggac tatagttctt ctagttgttt taggatatgt aggaatggca
    39541 agcttcatac aagaaggagt cttttatatt ccggctccct gggatagttt gtctgtcttt
    39601 acgatttcgc tagttatcgg tatttggaat tggaaagaag cggtctttcg tccatttgtc
    39661 agtatgatta ttgcccatct tgtggtgggt tctctgctcc gttattatga gtggatggga
    39721 atttcaaatg ttttccttac aaaagttatt cctttagctg tcctctttat tggaatcttt
    39781 gtcttgttcc gtgggtttaa gaagataaaa tggagtgaag tatagtcaaa aagccgttgc
    39841 aaagcggttt tttgttataa tgaagggaag aatgttagaa attaaaggag aaaaatttga
    39901 tgagatacat aactcttggt caagatgaca aagaattatc agaaattgtt ctcggaatga
    39961 tgagaataaa agataaatct gtaaaagaag ttgaagagct tgtagaaaca gcactttctg
    40021 ttggaatcaa tgccttcgac ttggctgata tttatggtcg tggtcgttgt gaagaactgt
    40081 taggtcttgt cctaaaaaat cgtccagatt taagagaaaa gatgtggatt cagtccaaat
    40141 gtggcattcg cattgaagaa tttacctatt ttgatttttc taaggactat attataaaat
    40201 cagtagacgg tattttgcaa agattgaaga ttgatcatct agatagcttg ctccttcatc
    40261 gaccagatgc tttgatggaa tctgaccaag tagcagaagc ctttgatctc ctttataaac
    40321 aaggtaaagt tcgagatttt ggagtttcta atcaaaatcc tatgatgatg gagttgctta
    40381 aaaaagatgt caagcagccg ttagctgtta atcagctaca attgagtgcg gcttttactc
    40441 caggatttga atcagctttt catgttaata tggaagatag tcaagcagct atgcgagatg
    40501 gcagcatttt tgaatattgc caattacacg atgtggtcat tcaagcatgg tctgtcttgc
    40561 aattcgggta ttttaaaggg aactttgttg gaaatgagaa atttcaagct ttaaatcaag
    40621 tacttgatcg tttagctatt aaatatggag taacctcttc aactattgcc atttcttgga
    40681 tattgcgtta tccagcaaaa atgcaggcag tcgtaggtac aacaaatcct aagcacttga
    40741 gagaagttag ccgagcggca aactttagct taacaagaaa agaatggtat gaaatttatc
    40801 ttgctgcagg gaataatttg ccgtaagtag tagcaggttt gaataactca cagtcaaaaa
    40861 gccgtataaa gtggtttttt gctataatta aatgaagaat gtagaattaa aggagaaaaa
    40921 catgacattt gaagagatcc tgcctgggtt aaaggctaag agaaaatatg tacgaactgg
    40981 ttggggaggt gcggaaaact atgtccaact ctttgatacc atcgagcaaa atgggcttgc
    41041 acttgaaatg acaccttatt tcctaatcaa cgtttctgga gaaggagaag gtttttccat
    41101 gtggagcccg acagtttgtg atgttttggc aacggattgg gtagaagtgc atgactaaac
    41161 gtgtactcat tacaggagtg agttcaggga tcggattggc tcaagctcgc ctctttttag
    41221 agaagggcta tcaagtttat ggagttgacc aaggtgaaaa gccactctta gagggtgatt
    41281 ttcacttttt acagagagat ttgaccttgg acttggaacc tatttttgac tggtgccctc
    41341 aggtggatgt tttgtgtaat actgccggag ttttggatgc ttacaaacca ctgttggaac
    41401 aaacggcgca ggacattcaa gagatttttg aaatcaacta cattattcca gtagagttga
    41461 ctcggtatta tttgacacaa atgctggaaa ataaaaaggg aatcatcatc aatatgtgtt
    41521 ccattgcttc tagcctagca ggtggaggtg gtcacgccta tacttcatcc aagcatgcct
    41581 tggctggctt caccaagcag ttggctctag actatgctga agctaggatt caggtctttg
    41641 gtatcgctcc aggagcagtc aagacagcta tgaccgctgc ggattttgag acaggtggct
    41701 tagctgactg ggtggctagt gaaaccccaa tcaagcgctg gattgaacca gaggaagtgg
    41761 cagaagtcag tctctttttg gccagtggaa aggcatctgc catgcaggga caaattctga
    41821 caatagatgg tggctggtct ttgaagtagg aggagttgga tggaaatcaa aaatcacttt
    41881 ggggtctact gtgtttgctt tgaaaatgga aagttacttt gcattgaaaa aacgagaggc
    41941 ccttatcaac atcggtatga tctacctgga ggcagtcagc aacttggtga aggactgacg
    42001 gaaacgctga ctagagaagt tatggaagag acgggattta ctgttagaag ctactctaat
    42061 cctcgaatct acgatgtttt cgtcagggaa gagttaaaaa attttatggt tcaccatgtc
    42121 atagccttgt atgatgttga aatgaatgag agtgcacctc aagttacgat ttcggaagct
    42181 gtgtctgatg gtgcgaatga ttcacttgga tatatttgga tggatattca agagattaca
    42241 gaagaaaatg catcgccatt agtcttgaag gttaagtctg aattattagg attgccagaa
    42301 ctggacaaga cttcttacat gaattggaag gtgaagtaga gggataatgg aactatttaa
    42361 aacatggaag aaaaatatgg ttctctatgg tcttaaatct caaattggaa ctgtctaccg
    42421 aaacaatgat aggacaacaa gcttttatga tgttgggaat tttctatacc tagcagggga
    42481 gttggattcc agattttggg aagattttgt tagaaaatat ggtttagatt ataagattat
    42541 tatttcagaa aatactaatt ggcaagattt tctgcatcga aaagtggggc taaattcttt
    42601 tactcgctat tcttttaaag ataaggcaaa ttttcaagtt gaatttttaa ataatctagt
    42661 tactcattta gaggaaggtt acaatattgt gcctattgat aatcatattt ataactgctt
    42721 ttctacggaa gaatggtcac aggatttaca gggggatttt gagtcctatc aggattttgt
    42781 tttaaaaggt ggatttggct ttgtgattct taaaaataat gaactgattg ctgggatttc
    42841 ctcagggtta gtttaccgta aagcagttga agtggaagtt gcaactagac caaacgaaca
    42901 aggaaatgga tttgctaaaa agcttggtgc tgcaatgatt ctagagagtt taaatagaga
    42961 tatgtttcca ctttgggatg ctcataatga ggcttccaaa aaagtagcag aatttttagg
    43021 atatgagtta tctgaacctt atgaagcttt tgaactagag gaaattttga tataattata
    43081 tatgatattg tatcttttaa gacgaggtga atggctatga gaaatcaact tgcccttagt
    43141 ggcgaaaaaa ttcttgaaaa aatttatcct caactatttc accacgtcgg catgattcgt
    43201 ggggaatatt tgttgagaga gcttaatcaa aacatcatat tagcaagttg tcagcaattt
    43261 gtaaaagatt atctagagac tatctgctcc ctgtactcag atgaagaagt ttggtatcgt
    43321 ttttctgaat taacgaatac agaagccaat tgtttagtgg ggactagaga gttttttgac
    43381 gaagggcatc ccttgtttgg ctatagagga accaggcgtt tactggcgtg tttggatgaa
    43441 tttcaggctg aagcatatgt cgttacagaa gtttatcaaa ccaatcccaa tctatctctt
    43501 atctttcctt ttgtcaatga tgccgaccaa ttaaaacaag ctattacagt attgcgtcag
    43561 cagggtttta ctgggaaagt cggaacgatg attgaattac cgtcagcgta ttttgactta
    43621 tctagtatac tggaaacggg catttcaaag attgtagttg gaatgaatga tttgacttcc
    43681 tttgtttttg cgactatgag aaacagtcaa tggcatgata tggaaagtcc aataatgtta
    43741 gatatgctaa gagatatgca ggataaagca agaaagaaca agattgattt tgctgtagca
    43801 ggctatctga atacttcttt catacaaaaa atgaatcagt tgggtatcaa gtgcattatc
    43861 cactacagtt ctattccaga gatttttgat ttagagattg accatccaga tcatcttaaa
    43921 cacataaaag aagaaagtaa aaaattacaa aggagtaccc atgataccgc aagaaatgtg
    43981 gaataaatac aagcaaatca atcctttgat cggagatgaa atcgatgctt gggcttttgg
    44041 agttgaacca gatcttttag cggatttggt gtttaaagga gaaaagacag caacagcatc
    44101 agcctatgac ctctatgtac tagaagacga accacttccc caagtaggga ccttcgatat
    44161 cattttagat agtcaaaatc agtctgtctg cattgtcgaa attacaaagg tttctgttga
    44221 actcttcaat caagtttctg cgcaacatgc ctttaaggaa ggtgagggag acaaatcact
    44281 tgcctattgg cgccaggttc atgaggactt tttcacagac tgtttgggtg aagtagggct
    44341 gacttttaca cctgaaagca aggttgtttt agaagaattt cgcaaggtct acccactgta
    44401 gactattaga aggaagaaag ttttggaaat cgctgtccaa tccttttttt tcaagcaaaa
    44461 tatgatataa taagtttgtt tgaagaagag cagcagctct taaacttaga ataggagaaa
    44521 actatgcaag cagttgaaca ttttattaag caatttgttc ctgaacatta tgatttattt
    44581 ttagatttga gtcgtgagac caagactttt tctgggaaag tgaccatcac tggtcaagca
    44641 cagagtgacc gcatctccct ccaccaaaaa gacttggaaa tcacctctgt agaagttgca
    44701 ggtcaagctc gtccatttac agttgaccat gacaatgaag cccttcatat cgaattggct
    44761 gaggctggtc aagttgaatt ggttcttgcc ttttctggta aaattacaga caacatgaca
    44821 gggatttacc cttcttatta tacagttgat ggagtcaaga aggaggtctt gtctactcag
    44881 ttcgagagcc attttgcgcg cgaagctttc ccatgtgtgg atgagcctga agccaaagca
    44941 acttttgacc tctctcttcg ctttgaccaa gcagaaggtg aattggcctt gtcaaacatg
    45001 ccagaaatcg atgttgaaaa ccgtaaggaa acaggtatct ggaagtttga gacaacacct
    45061 cgcatgtctt cttacttgtt ggcctttgtt gctggtgatt tgcaaggggt gaccgctaaa
    45121 actaaaaatg gtaccctggt aggtgtctac tcaaccaaag cacatccact ttcaaatctt
    45181 gatttctcac tggatatcgc tgttcgctct atcgagtttt acgaagatta ctatggagtt
    45241 aagtatccaa ttcctcaatc tctccacatc gcccttcctg acttctcagc tggtgctatg
    45301 gaaaactggg gtcttgtgac ctaccgtgaa gtttacttgg ttgtcgatga gaactctaca
    45361 tttgctagcc gtcaacaagt tgcccttgtt gtggcccatg aattggctca ccaatggttt
    45421 gggaacctcg tgactatgaa atggtgggat gacctttggc tcaatgaaag tttcgctaat
    45481 atgatggaat acgtctgtgt ggataccatc gaaccaagct ggaatatctt tgaagatttc
    45541 caaacaggtg gagtacctct tgctcttgaa cgtgacgcta ctgatggcgt tcagtctgtc
    45601 cacgtcgaag ttaaacatcc agatgaaatc aatacactct ttgacggcgc tatcgtctat
    45661 gccaaaggaa gccgtctcat gcacatgctt cgccgttggc taggagatgc tgattttgct
    45721 aaaggtttgc atgcctactt tgaaaaacac caatacagca acaccattgg tagtgacctt
    45781 tgggatgccc ttggtcaagc gtcaggacgt gatgtcgcag ccttcatgga ttcttggttg
    45841 gaacagcctg gttacccagt tcttactgtc aaagttgaaa atgatgtctt gaagatttca
    45901 caaaaacaat tcttcatcgg tgagaacgaa gacaagaacc gtctctgggt ggtgcccctc
    45961 aatagcaact ggaaaggctt gcctgataca ctcgaaactg aaagtatcga aatccctggc
    46021 tacgcagctc ttcttgctga aaatgaagga gctcttcgtc tcaacactga aaatactgcc
    46081 cactatatta ccgactatca aggagacttg ttagaagctg ttcttgctga gctagagaca
    46141 cttgataaca caagcaaact gcaaattgtt caagaacgtc gtttgttggc tgaggcaggg
    46201 cacatttctt atgcagactt gcttccagtt cttgataaac ttgctaagga agagtcttat
    46261 ctggtggttt cagctgtttc tcaagtgatt tcagcccttg agcgctttat tgatgaagga
    46321 acggatgctg aaacagcctt caaaggactg gttgctaaat tggctcgtca taactatgac
    46381 cgtcttggtt ttgaagctaa agacggagaa tcagatgagg atgaattggt tcgtcagctg
    46441 gctgtttcga tgatgattcg ctcaaatgat gcagaagctc gtcaagtcgc tagccaaatc
    46501 ttcgcaacac acaaggagaa tcttgcagaa ctcccagcag ctattcgttc acaagttctg
    46561 attaatgaga tgaaacatca tgagactaaa gacttgttag cactttatct tgatacttat
    46621 actcacgcaa cagatgctgt ctttaaacgc cagttggcag cagctcttgc atacagtaca
    46681 gatgcggata atatccaaaa cttgattact tcttggaagg acaaatttgt ggtcaaacca
    46741 caggacttgt ctgcttggta ttaccaattc ctagctcatc aagcaactca gaaaacagct
    46801 tggtcttggg cgcgtgaaaa ctgggcttgg attaaggcag cccttggagg agatatgagc
    46861 tttgatagct ttgttatcct tcctgctcat gtatttaaga ctcagcaacg cttggcggaa
    46921 tacaaggagt tctttgagcc gcaactttct gaccttgctc ttagccgtaa catcggtatg
    46981 ggaatcaagg aaattgcagc acgtgttgac ttgattagcc gtgaaaaagc tgcagtcgaa
    47041 gcagttgttc ttcaatacgg aaatgcataa ataagcctaa aataaaaa
//
LOCUS       DBERCW010000012        46758 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.012, whole genome shotgun sequence.
ACCESSION   DBERCW010000012 DBERCW010000000
VERSION     DBERCW010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 46758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.012"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..721
                     /locus_tag="ACL72M_000862"
     CDS             <1..721
                     /locus_tag="ACL72M_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS0716017.1"
                     /translation="EIQSIFIEHKGNYAYRRIHLELRNRGYLVNHKRVQGLMKVLNLQ
                     AKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPASTQKLYLSPV
                     LDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLE
                     GKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNN
                     KRIKVKLKGLSPVQYRTKSFG"
     gene            complement(849..1097)
                     /locus_tag="ACL72M_000863"
     CDS             complement(849..1097)
                     /locus_tag="ACL72M_000863"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716018.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(1045..2127)
                     /locus_tag="ACL72M_000864"
     CDS             complement(1045..2127)
                     /locus_tag="ACL72M_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS0716019.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2253..3035)
                     /gene="gatD"
                     /locus_tag="ACL72M_000865"
     CDS             complement(2253..3035)
                     /gene="gatD"
                     /locus_tag="ACL72M_000865"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGS0716020.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3035..4378)
                     /gene="murT"
                     /locus_tag="ACL72M_000866"
     CDS             complement(3035..4378)
                     /gene="murT"
                     /locus_tag="ACL72M_000866"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGS0716021.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4477..5793)
                     /locus_tag="ACL72M_000867"
     CDS             complement(4477..5793)
                     /locus_tag="ACL72M_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGS0716022.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5986..7212
                     /locus_tag="ACL72M_000868"
     CDS             5986..7212
                     /locus_tag="ACL72M_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGS0716023.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7411..8985
                     /locus_tag="ACL72M_000869"
     CDS             7411..8985
                     /locus_tag="ACL72M_000869"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0716024.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9250..10038
                     /gene="codY"
                     /locus_tag="ACL72M_000870"
     CDS             9250..10038
                     /gene="codY"
                     /locus_tag="ACL72M_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGS0716025.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10038..10613
                     /locus_tag="ACL72M_000871"
     CDS             10038..10613
                     /locus_tag="ACL72M_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS0716026.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10695..10780
                     /locus_tag="ACL72M_000872"
     tRNA            10695..10780
                     /locus_tag="ACL72M_000872"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10729..10731,aa:Leu,seq:aag)
     gene            11063..12193
                     /locus_tag="ACL72M_000873"
     CDS             11063..12193
                     /locus_tag="ACL72M_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716027.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12694..13452
                     /locus_tag="ACL72M_000874"
     CDS             12694..13452
                     /locus_tag="ACL72M_000874"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0716028.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13540..14052
                     /locus_tag="ACL72M_000875"
     CDS             13540..14052
                     /locus_tag="ACL72M_000875"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGS0716029.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14234..15178
                     /gene="metA"
                     /locus_tag="ACL72M_000876"
     CDS             14234..15178
                     /gene="metA"
                     /locus_tag="ACL72M_000876"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGS0716030.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            15187..15864
                     /locus_tag="ACL72M_000877"
     CDS             15187..15864
                     /locus_tag="ACL72M_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS0716031.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15962..16720
                     /gene="tpiA"
                     /locus_tag="ACL72M_000878"
     CDS             15962..16720
                     /gene="tpiA"
                     /locus_tag="ACL72M_000878"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGS0716032.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16758..18263
                     /gene="lytC"
                     /locus_tag="ACL72M_000879"
     CDS             16758..18263
                     /gene="lytC"
                     /locus_tag="ACL72M_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGS0716033.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18761..19279
                     /locus_tag="ACL72M_000880"
     CDS             18761..19279
                     /locus_tag="ACL72M_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGS0716034.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            19409..19915
                     /locus_tag="ACL72M_000881"
     CDS             19409..19915
                     /locus_tag="ACL72M_000881"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGS0716035.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19915..20085
                     /locus_tag="ACL72M_000882"
     CDS             19915..20085
                     /locus_tag="ACL72M_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716036.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            20117..21349
                     /gene="clpX"
                     /locus_tag="ACL72M_000883"
     CDS             20117..21349
                     /gene="clpX"
                     /locus_tag="ACL72M_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGS0716037.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21358..21945
                     /gene="yihA"
                     /locus_tag="ACL72M_000884"
     CDS             21358..21945
                     /gene="yihA"
                     /locus_tag="ACL72M_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGS0716038.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHAPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21956..22336
                     /locus_tag="ACL72M_000885"
     CDS             21956..22336
                     /locus_tag="ACL72M_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGS0716039.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22388..23278
                     /gene="rapZ"
                     /locus_tag="ACL72M_000886"
     CDS             22388..23278
                     /gene="rapZ"
                     /locus_tag="ACL72M_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGS0716040.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23275..24252
                     /locus_tag="ACL72M_000887"
     CDS             23275..24252
                     /locus_tag="ACL72M_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGS0716041.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24249..25160
                     /gene="whiA"
                     /locus_tag="ACL72M_000888"
     CDS             24249..25160
                     /gene="whiA"
                     /locus_tag="ACL72M_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGS0716042.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25194..26162)
                     /locus_tag="ACL72M_000889"
     CDS             complement(25194..26162)
                     /locus_tag="ACL72M_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS0716043.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEDYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQTLQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            26298..27155
                     /gene="cdaA"
                     /locus_tag="ACL72M_000890"
     CDS             26298..27155
                     /gene="cdaA"
                     /locus_tag="ACL72M_000890"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGS0716044.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            27142..27921
                     /locus_tag="ACL72M_000891"
     CDS             27142..27921
                     /locus_tag="ACL72M_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGS0716045.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27945..29297
                     /gene="glmM"
                     /locus_tag="ACL72M_000892"
     CDS             27945..29297
                     /gene="glmM"
                     /locus_tag="ACL72M_000892"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGS0716046.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29371..29745
                     /locus_tag="ACL72M_000893"
     CDS             29371..29745
                     /locus_tag="ACL72M_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGS0716047.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29747..30595
                     /locus_tag="ACL72M_000894"
     CDS             29747..30595
                     /locus_tag="ACL72M_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0716048.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30872..31639
                     /gene="dapB"
                     /locus_tag="ACL72M_000895"
     CDS             30872..31639
                     /gene="dapB"
                     /locus_tag="ACL72M_000895"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGS0716049.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31636..32835
                     /locus_tag="ACL72M_000896"
     CDS             31636..32835
                     /locus_tag="ACL72M_000896"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGS0716050.1"
                     /translation="MRLMQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVI
                     KETYQSLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            32832..34703
                     /locus_tag="ACL72M_000897"
     CDS             32832..34703
                     /locus_tag="ACL72M_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0716051.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAQDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34846..36030)
                     /gene="mntE"
                     /locus_tag="ACL72M_000898"
     CDS             complement(34846..36030)
                     /gene="mntE"
                     /locus_tag="ACL72M_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGS0716052.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36334..39030
                     /locus_tag="ACL72M_000899"
     CDS             36334..39030
                     /locus_tag="ACL72M_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS0716053.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            39043..39834
                     /gene="yghU"
                     /locus_tag="ACL72M_000900"
     CDS             39043..39834
                     /gene="yghU"
                     /locus_tag="ACL72M_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGS0716054.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLRTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39950..40360
                     /locus_tag="ACL72M_000901"
     CDS             39950..40360
                     /locus_tag="ACL72M_000901"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS0716055.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40372..41967
                     /locus_tag="ACL72M_000902"
     CDS             40372..41967
                     /locus_tag="ACL72M_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716056.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGRTFEGQVGKDSYLKTFKVQ"
     gene            42146..42310
                     /locus_tag="ACL72M_000903"
     CDS             42146..42310
                     /locus_tag="ACL72M_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGS0716057.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKENKDKFLSILTSLAGLALV
                     LVAVWLGWPK"
     gene            42389..43117
                     /gene="yaaA"
                     /locus_tag="ACL72M_000904"
     CDS             42389..43117
                     /gene="yaaA"
                     /locus_tag="ACL72M_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGS0716058.1"
                     /translation="MKILIPTAKEMNTDLPSIETTLLRSESQAVLDALALYSASQLES
                     FYKVSAEKAAEECQNIQALKRQTAQHYPALKLFDGLMYRHIKRDKLTEVEQAYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDEAVKQEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(43168..44652)
                     /locus_tag="ACL72M_000905"
     CDS             complement(43168..44652)
                     /locus_tag="ACL72M_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator PRD
                     domain-containing protein"
                     /protein_id="HGS0716059.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            44868..>46758
                     /locus_tag="ACL72M_000906"
     CDS             44868..>46758
                     /locus_tag="ACL72M_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGS0716060.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETK
                     PAVTTTERSAVDSAILPISTAAKVETTSAPASTNEILKPSLSLSDARQNPAIRKEDVD
                     RGYSGFRTAGSGFRAAGSGFRAAGPENKPILNPNNTIAFSDISQGLHSFRGIGHSRGG
                     REIHYDVTTVRRGNRLNFTIKYSGPGEFVNNNFILDKGDGFGNPSNATITSSNPRVRE
                     QSKSISQGANYVSHSGYSMTSATSTNTEQTIRFSLPIINPNGDLSVRLKPVTFNVDQG
                     GGGAATSNDPYSNSNYYHRANPLLLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQ
                     TRLVREGEKGQRQITYKVHRFGNETLLGLPISNRVTKEAKPRIMQIGVAKELIDTVKP
                     RVDQNKVGDTNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAK
                     GEKGDR"
BASE COUNT        13931 a         8651 c        10568 g        13608 t
ORIGIN      
        1 tgaaattcaa tccattttta tcgaacacaa gggaaattat gcttatcgtc gaattcattt
       61 agaactaaga aatcgtggtt atctggtaaa tcataaaaga gttcaaggct tgatgaaagt
      121 actcaattta caagctaaaa tgcgacagaa acgaaaatat tcttctcata aaggagacgt
      181 tggtaagaaa gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa caatggaaca
      241 gtgctacaca gatgtgactg aatttgccat tccagcaagt actcaaaagc tttacttatc
      301 accagtttta gatggcttta atagcgaaat tatcgcctat aatctttcaa cttcacccaa
      361 cttagaacaa gtacaaacaa tgttggaaca ggcattcaca gagaagcact acgagaatac
      421 gattctccat agtgaccaag gctggcaata tcaacacgat tcttatcatc agtttcttga
      481 gggtaaggga attcaagcat ccatgtcacg caagggaaac agccaagaca acggtatgat
      541 ggagtccttc tttgggattc tgaaatcgga aatgttttac ggttatgaga agtcgtttca
      601 gtcgcttaag caattggaac aagctattgt agactatatt gattactaca acaataaacg
      661 aattaaggta aaactaaaag gacttagtcc tgtgcaatac agaactaaat ccttcggata
      721 aattaattgt ctaactgttt gggggcagta cattttaaca cttgatacta tgcgttttat
      781 tgtgggaaga ttttcctcat tttctagtga aattgaactt tttctaacat cttttgatag
      841 atgacttctt aatcaattat catttccatt gttgtttctt ggggtttcat cccttgtctt
      901 tgataaaagc ggagagcacc ctcgttatca ttccagacac ttagggttag attattgcag
      961 ccaatttctt tagcataata gcagaaaaat gacaataaaa tagcccctag atattttgaa
     1021 aggaaagcat aggggctata tagtttaatc aaaataaagc aaatctttgc tggtgcttgt
     1081 aaagaggtcg aagccatcct tggtaacaac accgcagtct tcaatacgaa caccgacttt
     1141 accagggata tagatacctg gttcaacaga gaagcacatg ccttcttcga tgaccatgtc
     1201 gtttccttcc atgatagatg ggaattcatg gacatccata ccgataccat gcccgagacg
     1261 gtggttgaag tactcaccat aaccagcttt ttcgatgacc tcacgggcag cgcggtccac
     1321 ttcatgagca gtcacacctg gcttgataaa gtcaagagca gcttgttggg cttcaagagt
     1381 caagttgtaa atatctttct tgaattggtc tggtttgccg acagcgactg tacgagtcat
     1441 atctgacgca tagccattga ccagaacacc caggtcaaag aggagaagag catcattttc
     1501 aaccttatta gctgctggaa tgccgtgtgg attcgcagca ttatcaccag tcaagaccat
     1561 ggtatcaaag ctcatttcat aaccttcacg tttcatggca aagtcgattt gtgcgatgat
     1621 atctgtctca gtcttatcaa gagaaatatt gtcaaaacca acatgaacag ccttgtcagc
     1681 ataaagacct gcaaccatca ttttttgcac ttcatcagct gatttgatga ggcgcatgcg
     1741 ttggatacga ggagtgaggt tgtcaaactc agcagtctca aaaactgttt tcaaaccatg
     1801 gtatttggtc aagatgagat tgtcaaactc aacagcgaca cgtttgaagt caagttgtgg
     1861 aagagcatgt ttgatttttt gccatggatt ttcagaatcg acatagccca ctactgggaa
     1921 ggaaacggtg ctacttgcac gttctacttc aagagctggg acaaagagga gaggttcctg
     1981 atccgctagg acaaagagga acatttggcg ttcatgggga tcactgtaaa aaccagtgag
     2041 gtaattgatt gtgacggggt cagatacgac agcgacgtct agtttttctg attcaagata
     2101 tgttaggatt tgttgtaatt tagacatatg ctaccttctt tctacccctc tattttggca
     2161 aaaaatgaga gaaaatgcaa gggagaaggg taaaagaaaa gacaaaaaac tccgacaaga
     2221 taacggagtt ctttgatatc attttccttt gtttaagaaa agtcagcctt gcttttgacg
     2281 tcactgtact cttcagcgat ttcttggctg agaatgtcct cataggcagg gagttggatg
     2341 tcctgaccat atttcttctt gagggcagta gtaactaggc gataagccag attggcatta
     2401 cgagagagga taggcccgtg gaagtaggaa ccaaagacat tcttataatg aaccccttca
     2461 ccgacctttt cttcgttgtt tccatttcca tagacaacct gtcccagcgg tttttggtca
     2521 tcagagagga aggtacgacc ttggtgattt tcaaatccat agtaggtttc atcgaaatct
     2581 tcattgtgaa tcttgatgtc accgataaaa cggttattgg tctggttgag cgtgtagtgt
     2641 cccatgaccc ctagcccttc gatacgtttt cctgaagctt caacataata ttgacccaat
     2701 agttggaaac caccgcagat agccagaact acaccgtcgt tttggatgta gttgtcaatg
     2761 ctctcttttt tagcaggtag gtcgtctgca atgatacttt gttcaaagtc ttgaccacca
     2821 ccgaaaaagg cgatgtcgta gtgattttca tcaaagtcat catggagaga aacgatgtca
     2881 acggtcacat gggctcccag tttttcagcc acatacttga gcatgaggat gtttccattg
     2941 tccccgtagg tattcatgag atttccgtag aggtgggcaa tgttgagctg ataggggtaa
     3001 ttgctatctt ttgaggaaag tgaagtataa accattagtt catctccttt ctaacaatct
     3061 gacgactagc cagcagttca cgaaattcca gcatggcagt ataagttgcc agaatatagg
     3121 catgcttgca gtcttgattc tcaatggtct tgagaacttg ctccagatta ctcgtttcag
     3181 tgattttctc agctggatag ccagtcactc ggaggcgacg agcgatttca gaatgacgaa
     3241 caccgccagc gttgatttca ggaatgtcca tgtcagtgat ttgctcaaag tctgcatccc
     3301 agatccagct agtgtcaatt ccatctgcat agttggcatt aaggaggaca gataggctaa
     3361 atggataagg tgctagtttg atcatttcga tagcttgggt tgcaccgact ggatttttaa
     3421 tcaagacaag ggtacattcc ttgtcaccga tatgaaaggt ttcttggcgt ccaaagacag
     3481 cacggctctt gtcaaatccc tgtttgatga gttgggaatc tgcgccgagg aaacgggcga
     3541 tggccacagc agctagggcg ttatagatat tatagagccc gccgatttgg ataccgtatt
     3601 cttggccgtc tatgacaaag cgagagcgat tgttggtcaa ctcaaccagt tttgtcaaac
     3661 gatagtcgag atcaggacgt ttacatccac aaccttcaca gatataggca cccaagtttg
     3721 cataggtatt atgctcatat ttgaggatgc cttggcagtc aggacagaga atcccttcgg
     3781 tattgtagtg agcaagttgg gctggtcctt tttccaagtc aaaaccaaaa tactctatag
     3841 ggtttggaat agttggcttg tagaaaagtg gactgtctcc gttaaggaga acagtagcag
     3901 ttggaacttt tcgaatggca tccaatatca tgttataggt agtatagatt tcaccgaaac
     3961 ggtccatctg gtcacggaag atattagtaa tgacaaaaag actaggctgg atatagtcac
     4021 agatacgaga tagactggct tcgtcaattt cgaggacggc aatatttttc ccagtttttg
     4081 aagatttggc tgttaggaag gttgttgcaa tccctgtaat catgttggca ccgcttgggt
     4141 tggttagaac ttgaccataa acctctttta aaatgccgac agtgagggca gttgtcaggg
     4201 tttttccatt tgttccagtg acaacgacaa tctcgtagtt cttagctagg ctttgtaaaa
     4261 tatctttatc aaattgaagg gcgactttcc ctgggagcgt acttccacgt ccaagacggc
     4321 ttaaaacgaa gtgggaagaa cgcccagcaa gaaggcccaa agtagttttt aagttcatgt
     4381 ttctattata tcacaaaaga gggaaaagac agatttggtg tttcgtagaa gtaaaaacag
     4441 cccaaagagg gctgtcagtt aagatgagat ttcaacttaa atcgcaaaca agtcattcaa
     4501 gttctcagcc aaggttgggt gagtgaagat ttgttttgtg aagtaagtgt aaggaatctt
     4561 gttgtccata gcaacagtaa tgatgttgat gatttcttga gaaccttctg agaagatgct
     4621 tgcaccaaga atttcttttg tttcagtatt aacaacagct ttgaaagctc cgcgaaggtc
     4681 tccatttacg tgaccacgag gcatggctgc aacagggatt tctttcactg cgtatggaag
     4741 tttcaaatca gctgcttggc tttcagtcaa accaacttgt gaaagtgcag gtgtgatgaa
     4801 catagtattt ggcacattga gacggtcctc aagtgtgtag ctgccatctc cagcaaggta
     4861 gctgtaaaca acacggaagt catcaagtga aatgtaagta aattgaaggc caccgttgac
     4921 atctccaact gcaaagacac caggaacgtt tgtttgacag tgtttgtcta ctttaatagc
     4981 accacgttca gttagttcaa tatctgtatt ttcaagttga agtggttcta catttggttt
     5041 gcgtccagtt gcgtagagaa gggcgtcgaa acggtaagtt tcgtcttcag ttacgacaag
     5101 cacttggtca ccatcgtttt tgatttcagt agtatggata ttttgaagca attcaatgcc
     5161 atcttcttcc atgtattgtt tagcaagagc tgcgatggaa ggttctgcac gaggtaggaa
     5221 tgtatccaag gcatctagga ctgtgacctt gcttccaagt ttgttgtaaa ggccggcaaa
     5281 ttcaagaccg atatttccgc caccaaggat tccaagtttt tcaggtaatt tgtccaagct
     5341 ttggatacct gttgagtcaa agatgttttt gcttgtagca agtccaggaa ttggcaagac
     5401 gtttgaaaca gcaccagtgt tgatgacgat tgtttcagca gtcagttctt tcttttcatc
     5461 accagcttgg atttcgatga ctttatttga aaggaagtga gcttccgcat caaagatatc
     5521 tacgcctgta ccagcaacag tcgcatagtt tttaccgttg aggcgaccag tgatcgtgtt
     5581 tttagtagca atcacttctt caaaagacaa gtccttttca gcagcaacta gcaaggtttt
     5641 agttgggata caaccaatgt tgatacaagt tccaccgtac atagccttgc tgcgttcaac
     5701 gagggcaact tttttgccag ctgaagccaa tttacctgct agtgttttac cagctttacc
     5761 aaatccaata acaattaaat cgtatgttaa catttatctt cctcctattc gaatttcatt
     5821 ctagcacaag aaaaaaactt ttgcacaatt ctgctacgga aaagacagaa aaagataaaa
     5881 acgctttcca gacaaaaaac tagtaatttt ttgacaagct tgataaacta aaatcctatc
     5941 tatttttata taagaaagaa taaatgttcg aaaataggag gttttatgaa atcgaatcgt
     6001 tatattattg cctttgctgg ggtcatttta cacttaatgc tgggttcgac ttatgcttgg
     6061 agtgtttatc gtaaccctat tattgaaaaa acgggatggg atcaggcttc tgttgccttc
     6121 gcctttagtc tagcaatctt ttgtttgggc ttatcggctg catttatggg gcgtttggta
     6181 gaaaaatttg gtccgaaagt catggggagt ctatctgctt ttctatacgc aggtggaaat
     6241 atcttaacag gatttgcaat agaccgtcag gaactgtggt tgttgtatct agcttatggc
     6301 attttaggtg ggcttggttt gggagcaggc tatattaccc ctgtgtcaac gattataaaa
     6361 tggtttcctg ataaacgtgg tctcgcaaca ggtttagcga ttatggggtt tggttttgct
     6421 tctttattga ctagtcccat agcgcaacac ctcatcgcag gggtagggat tgtagaaact
     6481 ttttatattt taggagcaag ttactttatt atcatgctcc tagcttcaca attcattaag
     6541 cgtccaaatg agcaagagct tgcaatttta tcttcttcag ggaaagaaaa aacagcctct
     6601 ttgacgcaag gaatggctgc aaatcaggct ctaaaaagca atcggtttta tatgctttgg
     6661 attattttct ttatcaacat agcttgtggt ttaggcttaa tttcagcggc atcgccaatg
     6721 gcacaggaga tggctggctt gtctacaagt catgcagcag taatggtggg tgttttgggg
     6781 attttcaatg gatttggtcg cttgctctgg gcgagtttgt ctgactatat cggtcgccct
     6841 ctaaccttta gtatattact gcttgtcaat cttttctttt ctctctcact ttggctcttt
     6901 acagattccg ttttatttgt agttgctatg tctattttga tgacttgcta tggagctggt
     6961 ttttctttga ttccagctta tctcagtgat atttttggaa ccaaggaatt ggccgctctg
     7021 catggttata ttttaacagc ttgggcaatg gctggtttag cgggacctat tttattagca
     7081 gagacttata aaatggctca ttcgtacaca caaaccttgt tcgtttttct cattttatac
     7141 agtatcgcct tggctttgtc ttattatcta ggtcgttcaa tcaaaaaaga aagtcaaaaa
     7201 ccgcttacat gattttctgt agaaatgggg ctatcttttg ctctggtctt gtgttatact
     7261 agataggttg caaagaaaac agtacttttc ttttgtggaa aagaagcaac acgattttat
     7321 atctagttat atgaaaatac gtcataaaaa gaaaagtata aactaagccc tatagggtgg
     7381 cttcgcacca cctttagaaa gaagaataac gtgaaattta atgaattaaa cttgtctgct
     7441 gatttgctag cagaaattga aaaagctggt tttgtagaag ctagtcctat ccaagaacaa
     7501 actattcctt tggcccttga aggcaaggat gttatcggtc aagctcagac tggtacagga
     7561 aaaactgcag cctttggctt gcctaccctt gaaaaaatcc gtatagaaga agcgactatt
     7621 caagccttgg tcatcgctcc aactcgtgaa ctagctgtcc aaagtcaaga agaactcttc
     7681 cgctttggtc gtagtaaggg agtcaaagtc cgttcagtat atggcggatc aagcattgaa
     7741 aaacaaatta aggctcttaa atctggtgcc catatcgtgg tgggaactcc aggtcgcctc
     7801 ttggacttga ttaaacgcaa ggccttgaaa ttacaagaca ttgaaaccct tatccttgac
     7861 gaagcggatg aaatgcttaa catgggcttc cttgaagaca tcgaagccat tatttcccgt
     7921 gtacctgaga accgtcaaac tttgcttttc tcagcaacta tgccagatgc catcaaacgt
     7981 atcggtgttc agtttatgaa agcccctgaa catgtcaaga ttgcggctaa ggaattgaca
     8041 acagaattgg ttgaccagta ctatatccgt gttaaggaac aagaaaaatt tgacaccatg
     8101 actcgtctca tggatgtggc acaaccagaa ctcgctattg tatttggtcg taccaaacgc
     8161 cgtgtggatg aattgactcg tggtttgaaa attcgtggct tccgtgcaga aggaattcat
     8221 ggcgacctag accaaaacaa acgtcttcgt gtccttcgtg actttaaaaa tggcaatctt
     8281 gatgttttgg ttgcgacaga cgttgcagcg cgtggtttgg atatttcagg tgtgacccat
     8341 gtctacaact acgatattcc acaagatcct gagagttatg ttcaccgtat cggtcgtaca
     8401 ggtcgtgctg gtaagtcagg tcaatctatt acttttgttg ctccaaacga aatgggttac
     8461 cttcaaatca ttgaaaactt gactaagaaa cgcatgaaag gtctcaaacc tgcaagtgta
     8521 gaagaatcct tccaatcaaa aaaacaggta gctctcaaga aaatcgaacg tgattttgca
     8581 gatgaaacca ttcgtgccaa ctttgagaaa tttggtaagg atgctcgcaa attggctgct
     8641 gagtttactc cagaagaatt ggcaatgtat atcttgagtc tgacagtcca agacccagat
     8701 agccttccag aagtggagat tgcacgtgaa aaaccactac cgtttaaacc atcaggtaat
     8761 ggtttcggtg gtaaagctaa gggaggtcgt ggaggccgtc gtggggacga ccgtcgagag
     8821 cgtgatcgtc gtggcaatgg tcgccgtgat gagttcaaaa aaggaagtcg tggcaacgat
     8881 cgttttgata aggaaaaacg ttaccgtaag gataataaaa aaccacgcaa tactttaagc
     8941 gaaaagcaaa caggctttgt tattcgtaac aaaggtgata aataagaaaa agcggttcaa
     9001 aatgaatcgc ttttttatat aaggagaccg aatgtgaaaa agacaaataa aattattata
     9061 ttatctttta taatattatg atacacaaaa ataggcgact tgtcaataga aaaggaacaa
     9121 tttaattaaa aatattctgg tttttaatta aattgtaagt caatgcaagt caataaggaa
     9181 ttttcagata attattgaaa aagagacgtt tttatgttat aatgatagcg attaaattcg
     9241 aggtgaaaaa tggcacattt attagaaaaa actagaaaaa ttacatcaat tttgaaacgc
     9301 tcagaggagc agttgcagga tgagctccct tacaacgcta ttacgcgtca gttagcggat
     9361 attattcatt gcaatgcctg cattatcaat agtaagggac gtctgcttgg ctattttatg
     9421 cgttataaaa caaatacaga tcgcgtagag caattcttcc aaactaagat tttcccagat
     9481 gactacgttc aaggggctaa tatgatttac gaaacagaag caaacttgcc tgttgagcat
     9541 gatatgagta ttttccctgt tgagagtaga gatgattttc cagatggctt gacgactatt
     9601 gcaccgattc atgtatcggg gattcgcctt ggttctttga ttatttggcg taatgataaa
     9661 aaattcgaag atgaggactt ggttcttgtt gagattgcca gtaccgttgt tgggattcag
     9721 cttcttaact tccaacgtga agaagatgag aaaaatattc gtcgtcgtac tgctgtcacc
     9781 atggcggtca ataccctttc ttactccgaa ctccgtgctg tttcagcaat tttaggggaa
     9841 ttaaatggaa atgaagggaa gttgactgcg tcagtgattg cagatcgtat cggaatcact
     9901 cgctctgtga ttgtcaatgc tcttcgtaaa cttgagtctg cggggattat tgaaagtcgc
     9961 tcacttggaa tgaagggaac ctatcttaag gtcttgattt cagatatttt tgaagaagtg
    10021 aagaaaagag attactaatg acaaaggctt taatttcgat tgattataca gaagattttg
    10081 ttgctgatag tgggaagctg acagcaggtg ctccagctca ggcgatttcg gatgccatca
    10141 gcaaggtaac tcgattagct tttgaacgag gagattatat cttctttact attgatgctc
    10201 atgaagaaaa cgattgtttc catccggaaa gtaagttatt tcctcctcat aatctgattg
    10261 ggacgagtgg acggaattta tatggagatt tggggatctt ttatcaagag catggttcag
    10321 acagtcgtgt cttttggatg gataaacgcc attactcagc tttttcaggg actgacctag
    10381 atattcgttt gagagagcgt agagtgtcta ccgttatctt aacaggtgtc ttgacggata
    10441 tctgtgtcct acatacagct atagatgcct ataatctagg atatgacatc gagattgtta
    10501 aaccagctgt tgcttccatc tggcctgaaa atcatcaatt tgccctaggt catttcaaaa
    10561 atacactcgg agctaagtta gtagatgaaa atctaaatga actttctgag taacctggtt
    10621 ggtgaaaatg aaaaaatttg aaaaaaagtg ttgacaagca tcccaaaagt tgatatacta
    10681 gtaaagtaat cgatgcgggg atggcggaat tggcagacgc gcaggactaa ggatcctgtg
    10741 accgctttag gtcgtgaggg ttcaagtccc tctctccgca taggaaaaga gttagctaaa
    10801 gctagctctt ttgtatttct ctaaaaaatt agaatccagt caaatgtagt ggagaatcag
    10861 cgaaaatatg ggaaaactga tccttgtttc tgcttttgtc atagaagaat aataaagatt
    10921 atcttcttca aattctccga tattctctaa agttttgtgc aagttgcaca gaactttttt
    10981 atttttttgg tcatcttgcc atagaaatat aaagcgtttt catctataat ataattatca
    11041 aaagacaaaa ggagttcacc tcatggtaga attgaatctt aaaaatattt acaaaaaata
    11101 tccaaacagc gaacactatt cagttgaaga tttcaacttg aacatcaaag ataaagaatt
    11161 tatcgttttc gtaggacctt caggatgtgg taaatcaact acactccgta tgattgctgg
    11221 tcttgaagac atcacagaag gtactgcatc tatcgatggc gtggttgtca acgacgtagc
    11281 tccaaaagac cgtgatatcg ccatggtatt ccaaaactac gctctttacc cacacatgac
    11341 tgtttatgac aacatggctt tcggtttgaa attgcgtaaa tacagcaaag aagacattaa
    11401 caaacgtgtt caagaagcag ctgaaatact tggattgaaa gaattcttgg aacgtaaacc
    11461 ggctgacctt tcaggtggtc aacgtcaacg tgttgccatg gggcgtgcga ttgtccgtga
    11521 tgcgaaagta ttcttgatgg acgaaccttt gtcaaacttg gatgccaaac ttcgtgtatc
    11581 aatgcgtgct gaaatcgcta aaattcaccg tcgtatcgga gctacaacta tctatgtaac
    11641 tcacgaccaa acagaagcga tgacacttgc agaccgtatc gttattatgt cagctactaa
    11701 gaaccctgct ggtacaggta ctatcggacg tgtagaacaa atcggtactc ctcaagaagt
    11761 ttacaaaaat ccagttaaca aattcgttgc aggattcatc ggaagcccag ctatgaactt
    11821 catcaacgtg aaattggttg gtagcgaaat tgtttctgac ggtttccgtt tgaaagtgcc
    11881 agaaggagca ttgaaagttc ttcgtgaaaa aggctacgaa ggaaaagaat tgatctttgg
    11941 tatccgtcca gaagacgtga atgcagaacc tgctttcctt gaaacattcc cagactgtgt
    12001 tgtaaaagcg actatctctg tatcagaact gcttggttca gaatctcacc tttactgcca
    12061 agttggtaaa gacgagtttg ttgcaaaagt tgatgctcgt gactacttgc aaacaggtgc
    12121 aacagttgag cttggatttg acttgaacaa agcacacttc ttcgatgtag aaactgaaaa
    12181 aacaatctac taagaataaa taaaattcaa agcactacaa gaaaagatat ctctttatca
    12241 attgtagtgg agagatatca gttaatctag ggagagaaac aaaatgcttc tctccttttt
    12301 gctagggaag tcatattata catctatatt gtgatgctct ttatactctt cgaaaatctc
    12361 ttcaaaccac gtcaacgtcg ccttgccgta cgtatgatta ctgacttcgt cagttttatc
    12421 tgcaacctca aagctgtact ttgagtagct tacggctagt ttcctagttt gctctttgat
    12481 ttccattgag tattatttgt gggtaccatc tacaagtgaa gctatatgcg taaactacgt
    12541 gagcaattga attcgaacta gagaggtaat aataaattta tgctatagtt atggtgactt
    12601 gtatgctttt gattctagtt tatcaaataa tagattagaa ttgtcagata atatcatttt
    12661 gtgttataat gaagaaaaaa cagaggtgtt caaatgtcag aagcaggtca taagttttta
    12721 gcaaaattgg ggaaaaaacg cttacgtcca ggtggaaagc gtgccacaga ttggttaatt
    12781 gcagaaggag gattttcaaa agaaaagaga atactagagg ttgcgtgtaa taggggaact
    12841 acagcaattg agttggcaca gcgttttggt tgcaagataa ctgctgttga tatggatgct
    12901 caagctttag aagtggctaa aaaatctgct ggaacggcag gtgttgctca tttaatcagt
    12961 tttgaaagag caaatgcaat gaaacttcct tatcaagatg ctagttttga tattgttata
    13021 aatgaagcta tgctgactat gcaagccgat caagctaaga aaaaatgtgt aatggaatat
    13081 ctaagggtat taaaacctgg aggtcttctc ttgacacatg atgtgcttct taaggaagct
    13141 aaagagtcta tcagacagga attatcacaa gcaattcatg taaatgtagg tcctttaact
    13201 caagatggtt gggaacaggt gatgatagaa tcaggttatt gtgatgtgaa agcattgact
    13261 ggtgaaatga cattaatgaa attatcgggt atgatttatg acgaaggttt gctaggaact
    13321 ttgaaaattt gtgtaaatgc ttgtaaaaag gagaatagaa agcagttttt aactatgtat
    13381 aaaatgtttg ctaagaataa acagaaattg ggctttattg cgatggctag ttataaatcg
    13441 tcaaaacgtt agataattat tgaagttaac ttttcctttt ttctttctta aaaaatatgc
    13501 tataatagag agtaaaaaac tttgaaagaa agaaaaaaga tgaatttaaa agattacatt
    13561 gcaacaattg aaaattatcc aaaggaaggc attaccttcc gtgatattag tcctttgatg
    13621 gctgatggaa atgcttatag ctacgctgtt cgtgaaatcg ttcagtatgc tactgacaag
    13681 aaagtcgaca tgatcgtggg acctgaagct cgtggattta tcgtgggttg tccagttgcc
    13741 tttgagttgg gaattggttt tgcgcctgtt cgtaagccag gtaaattgcc acgcgaagtt
    13801 atttctgctg actatgaaaa agagtacggt gtcgatacct tgactatgca cgcggatgcc
    13861 attaagccag gtcaacgtgt tcttattgta gatgaccttt tggcgacagg tggaactgtt
    13921 aaggcaacta tcgagatgat tgaaaaactt ggtggtgtta tggcaggttg tgccttcctt
    13981 gttgaattgg atgaattgaa cggccgtgaa aaaatcggtg actacgacta caaagttctt
    14041 atgcattatt aatgaaaaca gtccctaggg ctgttttctc tacactagga tataaaaata
    14101 gactataact agttagagaa aaactataat tgaaaactat atcttcttgc agtataataa
    14161 aaggactaag tgtttgagat ttgtcttcaa acacatgcaa ttattcctga gagagtacag
    14221 ttaggagagg gttatgccga ttcgaattga taaaaaattg ccagctgttg agattttacg
    14281 gacagagaat atctttgtca tggatgatca acgtgctgcc caccaagata tccgtccttt
    14341 gaagatttta attttaaatc tcatgccaca gaaaatggtc acagagaccc agttgttgcg
    14401 ccacttggct aatacacccc tacaactgga tattgatttt ctctatatgg agagccaccg
    14461 ttctaaaaca actcgttcag agcacatgga gaccttctat aaaacttttc ctgaagtcaa
    14521 ggatgagtat tttgatggga tgatcatcac gggtgctcca gttgagcatt taccatttga
    14581 ggaagtggac tattgggagg aatttagaca gatgcttgag tggtctaaga ctcatgtcta
    14641 ttcgaccctt catatctgtt ggggagctca ggctgggctt tatctgcgct atggtgtaga
    14701 aaaataccag atggacagta agctatcagg tatttatcct caggacaccc taaaagaggg
    14761 tcaccttcta tttagaggct ttgatgatag ctatgtatcc cctcattcac ggcacacgga
    14821 gatttctaag gaagaggtct taaacaagac taatctcgag attttatcag aaggacctca
    14881 ggttggggtt tctattttgg ccagtcgtga tttacgagaa atttatagtt ttggtcattt
    14941 ggagtatgac cgtgatacct tggcaaaaga gtattttcga gatcgtgatg caggtttcga
    15001 cccacatatt ccagaaaatt actttaaaga tgatgatgtt aatcaggtac cttgtctttg
    15061 ttggtcttca tctgcagccc tctttttcag taattgggta aaccatgcgg tctatcagga
    15121 gacgcctttt gactggagaa agatagaaga tgatgcatct gcatatgggt atttataaga
    15181 ggaattatga catatttaga cgcttttaaa tcaggtacct tggttttacc gagtgccctg
    15241 ctcttgcatt ttaaggaact ctttccttct agcgacgatt ttctggtttg gcaatttttc
    15301 tatttgcaaa atacgacagg cttagaagaa atgtcgccaa gccagattgc tgaaaggatt
    15361 ggcaaggaaa tttcggatgt caaccagtcc atttctaatc tgacggaaag gggactgctc
    15421 cagtatcgta ctatcgaatt aaatggcgaa attgaattgc tctttgatgc tagtttggcc
    15481 ttggaacgtt tggatgacct gtttggagca gttcattcaa gttcagacca gctaacacca
    15541 caaaaccagc tcaaggattt ggtggaaacc ttccagcagg agttgggacg attgttgacg
    15601 ccttttgaga ttgaggattt gaccaagaca ctaaaggaag atggaaccag tgctgacttg
    15661 attaaggagg ctcttcgtga agctgttttg aatggaaaac caaactggaa gtacattcag
    15721 gcgattttga gaaactggcg ccatgaagga atcaagagtg tggctcaaat tgaggccaag
    15781 agagcagaaa gagaagcaag caatcctcag ttgacacagg tatctgcaga tttcagaaat
    15841 gccatggatc tctggaagga ttaatccatg caagtaggct tgaaatccga gtaagatttg
    15901 caagctgtgt ataattgtga tagaataaat agaaaataaa ttgaaaaaag aggtatgtga
    15961 aatgtcacgt aaaccattta tcgctggtaa ctggaaaatg aacaaaaatc cagaagaagc
    16021 taaagcattc gttgaagcag ttgcatcaaa acttccttca tcagatcttg ttgaagcagg
    16081 tatcgctgct ccagctcttg atttgacaac tgttcttgct gttgcaaaag gctcaaacct
    16141 taaagttgct gctcaaaact gctactttga aaatgcaggt gctttcactg gtgaaactag
    16201 cccacaagtt ttgaaagaaa tcggtactga ctacgttgtt atcggtcact cagaacgccg
    16261 tgactacttc catgaaactg acgaagatat caacaaaaaa gcaaaagcaa tctttgcgaa
    16321 cggtatgctt ccaatcatct gttgtggtga atcacttgaa acttacgaag ctggtaaagc
    16381 tgctgaattc gtaggtgctc aagtatctgc tgcattggct ggattgactg ctgaacaagt
    16441 tgctgcctca gttatcgctt atgagccaat ctgggctatc ggtactggta aatcagcttc
    16501 acaagacgat gcacaaaaaa tgtgtaaagt tgttcgtgac gttgtagctg ctgactttgg
    16561 tcaagaagtc gcagacaaag ttcgtgttca atacggtggt tctgttaaac ctgaaaatgt
    16621 tgcttcatac atggcttgcc cagacgttga cggtgccctt gtaggtggtg cgtcacttga
    16681 agctgaaagc ttcttagctt tgcttgactt tgtaaaataa tcagtaagta gcaaaagcta
    16741 ggtggaacag cattcagatg tctgttacat tttttatagg agagcaaaga ttgaaaacaa
    16801 aaattggatt agcaagtatc tgtttactag gcttggcaac tagtcatgtc gctgcaaatg
    16861 aaactgaagt agcaaaaact tcgcaggata caacgacagc ttcaagtagt tcagagcaaa
    16921 atcagtcttc taataaaacg caaacgagcg cagaagtaca gactaatgct gctgcccact
    16981 gggatgggga ttattatgta aaggatgatg gttctaaagc tcaaagtgaa tggatttttg
    17041 acaactacta taaggcttgg ttttatatta attcagatgg tcgttactcg cagaatgaat
    17101 ggcatggaaa ttactacctg aaatcaggtg gatatatggc ccaaaacgag tggatctatg
    17161 acagtaatta caagagttgg ttttatctca agtcagatgg ggcttatgct catcaagaat
    17221 ggcaattgat tggaaataag tggtactact tcaagaagtg gggttacatg gctaaaagcc
    17281 aatggcaagg aagttatttc ttgaatggtc aaggagctat gatgcaaaat gaatggctct
    17341 atgatccagc ctattctgct tatttttatc taaaatccga tggaacttat gctaaccaag
    17401 agtggcaaaa agtgggcggc aaatggtact atttcaagaa gtggggctat atggctcgga
    17461 atgagtggca aggcaactac tatttgactg gaagtggtgc tatggcgact gacgaagtga
    17521 ttatggatgg tgctcgctat atctttgcgg cctctggtga gctcaaagaa aagaaagatt
    17581 tgaatgtcgg ctgggttcac agagatggta aacgctattt ctttaataat agagaagaac
    17641 aagtgggaac cgaacatgct aagaaaatca ttgatattag tgagcacaat ggtcgtatca
    17701 atgattggaa aaaggttatt gatgagaacg aggtggatgg tgtcattgtt cgtctaggtt
    17761 atagcggtaa agaagacaag gaattggcgc ataacattaa ggagttaaac cgtctgggaa
    17821 ttccttatgg tgtctatctc tatacctatg ctgaaaatga gaccgatgct gagaatgacg
    17881 ctaaacagac cattgaactt ataaagaaat acaatatgaa cctgtcttac cctatctatt
    17941 atgatgttga gaactgggaa tatgtaaata agagcaagag agctccaagt gatacagaca
    18001 cttgggttaa aatcatcaac aagtacatgg acacgatgaa gcaggcgggt tatcaaaatg
    18061 tgtatgtcta tagctatcgt agtttattac agacgcgttt aaaacaccca gatattttaa
    18121 aacatgtaaa ctgggtagcg gcttatacga atgctttaga atgggaaaac ccttattatt
    18181 caggagaaaa aggttggcaa tatacctctt ctgaatacat gaaaggaatc caagggcgcg
    18241 tagatgtcag cgtttggtat taagcgatga tttgaaagag ggatgtgata gtagcaccct
    18301 ctttttcttt gttttatgat agttcatcct cgagtaaatt caagatcttg ctcggaaatg
    18361 aagcttatat agtagattga atatagacaa ataccttgtg attggtaaaa cattttagaa
    18421 attcatttac ctttcctaat cgacttggtt tcatcttatt tcaatctatt atagtattgg
    18481 ggaatttctt caaaccacat cagcttggtc agttctacct gcgacctcaa aacttgtgct
    18541 ttggtcaagc tgggtttagt ttcctagttt gctgatggat ttccattgac tataagcatc
    18601 caaccctctt tttgtcttct aaagaattct taaattatca gtctattgca acttttctca
    18661 tgtgggtcat ttggcttgca attgtctttc cttagtagta tactgaggta gtaatcatta
    18721 agaagtggtt acataaaaat aatgaatgag gtaaaataaa atggtagaat tgaaaaaaga
    18781 agcagcaaaa gatgtcgcaa cattaacaaa agcagcgcca gtagcattgg caaaaacaaa
    18841 ggaagttttg aatcaagcag ttgctgattt gtatgtagct cacgttgctt tgcaccaagt
    18901 gcactggtat atgcatggtc gtggtttcct tgtatggcat ccaaaaatgg atgagtacat
    18961 ggaagctctt gatggtcatt tagatgaaat cagcgaacgc ttgatcacac ttggtggaag
    19021 cccattctct actttgacag agttccttca aaacagtgaa atcgaagaag aagctggtga
    19081 ataccgtaat gttgaagaaa gcttggaacg tgttctagct atttatcgct acctcatcac
    19141 tcttttccaa aaagcgttgg atgtgactga cgaagaaggc gatgatgtta caaacgatat
    19201 ttttgttggt gctaaggctg aacttgagaa aacagtttgg atgcttgccg cagaacttgg
    19261 acaagcacct ggtttgtaag aaacaagaca acatagataa atctgtagga aatttcttac
    19321 agattttttc tattttgtaa gctattccaa accagtcttt ttttgagttt tttgataaaa
    19381 tagtactatc agtgaaaagg atggaagcat gactaagaaa atcgtagcta tttgggccca
    19441 ggatgaagag ggtgtgattg gtaaggacaa tcgtctgcct tggcatttgc cagcagaatt
    19501 gcagcacttt aaagaaacaa ctctgaatca tgctatcttg atggggcggg taacctttga
    19561 tggaatgggg cgtcgcttgc ttccaaaacg ggagaccctg attttgacgc gtaatccgga
    19621 agaaaagata gatggggttg ctacttttca ggacgtccag tctgttcttg actggtatca
    19681 ggctcaagaa aagaatctct acattatcgg tgggaagcaa atttttcagg cttttgaagc
    19741 ttaccttgat gaagtgattg tcactcacat tcatgctcgg gtggaaggag atacctattt
    19801 ccctgaagag cttgacttgt ctctttttga gacagtttca agcaaatttt acgccaaaga
    19861 tgagaagaat ccttatgatt ttaccatcca ataccgcaag agaaaggaag tttaatggaa
    19921 cggagtttat ttggtctatt cacggctttt ctgtgtttca tctgctttct ggcaggagca
    19981 caagcttttc gtaaaaagcg ttacgggctt tctatcctcc tttggttaaa tgcctttacc
    20041 aatctggtca atagtattca tgctttttac atgaccttat tttagataga atgacagtat
    20101 agaatggaag gaaatcatgt ctacaaatag aaaaaatgat atgatggttt attgctcatt
    20161 ttgtggcaaa aaccaagaag aagtacaaaa aataattgct ggcaacaatg cttttatttg
    20221 taatgaatgc gtggagttag ctcaggaaat cattcgagaa gaattggttg aggaagtctt
    20281 ggcagacttg tctgaggtgc caaaaccaat tgaactcctc catatcttga accactatgt
    20341 aattggtcaa gatcgtgcca agcgtgcctt ggcagtggcg gtttataacc actacaaacg
    20401 catcaatttc cacgatacac gcgaagagtc agaagatgtg gatttgcaga agtcaaacat
    20461 tttgatgatt ggcccaactg gttcagggaa aactttcctt gcccagacct tggctaagag
    20521 cttgaatgta ccttttgcta ttgcggatgc gacagctctg acggaggctg gttatgtggg
    20581 tgaggatgtg gaaaatatac tcctcaaact cttgcaggtt gctgacttta acatcgaacg
    20641 tgcagagcgt ggcattatct atgtggatga aattgacaag attgccaaga agagtgagaa
    20701 tgtgtctatc acacgtgatg tttctggtga aggggtgcaa caagcccttc tcaagattat
    20761 cgagggaact gttgctagcg taccgcctca aggtggacgc aaacatccac aacaagagat
    20821 gattcaagtg gatacaaaaa atatcctctt catcgtgggt ggtgcttttg atggtattga
    20881 agaaattgtc aaacaacgtc tgggtgaaaa agtcatcgga tttggtcaaa acaataaggc
    20941 gattgacgaa aacagctcat acatgcaaga aatcatcgct gaagacattc aaaaatttgg
    21001 tattatccct gagttgattg gacgcttgcc tgtttttgcg gctcttgagc aattgaccgt
    21061 tgatgacttg gttcgcatct tgaaagagcc aagaaatgcc ttggtgaaac aataccaaac
    21121 cttgctttct tatgatgatg ttgagttgga atttgacgac gaagcccttc aagagattgc
    21181 taataaagca atcgaacgga agacaggggc gcgtggactt cgctccatca tcgaagaaac
    21241 catgctagat gttatgtttg aggtgccgag tcaggaaaat gtgaaattgg ttcgcatcac
    21301 taaagaaact gtcgatggaa cggataaacc gatcctagaa acagcctaga ggtgactatg
    21361 gaacttaata cacacaatgc tgaaatcttg ctcagtgcag ctaataagtc ccactatccg
    21421 caggatgaac tgccagagat tgccctagca gggcgttcaa atgttggtaa atccagcttt
    21481 atcaacacta tgttgaaccg taagaatctc gcccgtacat caggaaaacc tggtaaaacc
    21541 cagctcctga acttttttaa cattgatgac aagatgcgct ttgtggatgt gcctggttat
    21601 ggctatgctc gtgtttctaa aaaggaacgt gaaaagtggg ggtgcatgat tgaggagtac
    21661 ttaacgactc gggaaaatct ccgtgcggtt gtcagtctag ttgaccttcg tcatgccccg
    21721 tcagcagatg atgtgcagat gtacgaattt ctcaagtatt atgagattcc agtcatcatt
    21781 gtggcgacca aggcggacaa gattcctcgt ggtaaatgga acaagcatga atcagcaatc
    21841 aaaaagaaat taaactttga cccgagtgac gatttcatcc tcttttcatc tgtcagtaag
    21901 gcagggatgg atgaggcttg ggatgcaatc ttagaaaaat tgtgaggaaa agaaaatggc
    21961 aaaaacaatt catacagata aggccccaaa ggctatcgga ccctatgttc aaggaaaaat
    22021 cgttggcaac cttttgtttg ctagcggtca agttccccta tcccctgaaa ctggggaaat
    22081 tgtaggagag aatatccaag aacagacaga gcaagtcttg aaaaacatcg gtgctatttt
    22141 ggcagaagca ggaacagact ttgaccatgt tgtcaaaaca acttgcttct tgagcgatat
    22201 gaacgacttt gttcctttta atgaggttta ccaaacggcc ttcaaagagg aattcccagc
    22261 tcgttcagct gtggaggtag ctcgtcttcc tcgtgatgta aaagtcgaaa ttgaagtcat
    22321 cgcagagatt ggataagcta gttgaagttt ggtgttgcca aacttctttt gatataagga
    22381 gaaaaagatg acaaagaaac aacttcactt ggtgattgtg acagggatga gtggcgcagg
    22441 gaaaactgta gccattcagt ccttcgagga tctaggttat ttcaccattg ataatatgcc
    22501 gccagctctc ttgcctaagt ttttgcagct ggttgaaatt aaggaagaca atcctaagtt
    22561 ggccttggta gtggatatgc gtagccgttc tttcttttca gagattcaag ctgttttgga
    22621 tgagttggaa aatcaagatg gtttggattt caaaatcctc tttttggatg cggctgataa
    22681 ggaattggtc gctcgttaca aggaaaccag acggagtcac ccactagcag cagacggtcg
    22741 tattttagat ggaatcaagt tggaacgtga actcttggca cctttgaaaa atatgagcca
    22801 aaatgtggtg gatacgactg aactcactcc acgtgagctg cgtaaaaccc ttgcagagca
    22861 gttttcagac caagaacaag cccagtcttt ccgtatcgaa gtcatgtctt tcggatttaa
    22921 atatggaatc ccgattgatg cggacttggt ctttgatgtc cgtttcttgc caaatcccta
    22981 ttatctacca gaactgagaa accaaacggg tgtggatgaa cctgtttatg attatgtcat
    23041 gaaccatcct gagtcagaag acttttatca acatttattg gccttgattg agccgattct
    23101 gccaagttac caaaaggaag gtaagtccgt tttgaccatt gctatgggat gtacgggtgg
    23161 acaacaccgt agtgtggcat ttgctaaacg cttggtgcag gacttatcca agaattggtc
    23221 tgttaatgaa gggcatcgcg acaaagaccg cagaaaggaa acggtaaacc gttcatgaga
    23281 aaaccaaaga taacggtgat tggtggaggg actggaattc ccgtcattct aaaaagtctg
    23341 cgggaaaaag atgtggaaat cgcagctatc gtgacggtgg cagatgatgg tggttcttca
    23401 ggtgaactcc gaaaaaatat gcaacagttg acaccgccag gtgatcttcg taatgtcctt
    23461 gtggccatgt cggatatgcc taagttttat gagaaggtct ttcagtatcg gttctctgag
    23521 gatgccggag cctttgctgg ccatccattg ggaaatctca tcattgctgg cttgtcagaa
    23581 atgcagggtt caacctataa tgccatgcag ttattgagca aatttttcca tacaacaggg
    23641 aaaatttatc cttccagtga ccatcctttg acccttcatg cagtctttca ggatgggaca
    23701 gaagtggctg gagagagtca tattgtagac catcgaggca taattgacaa tgtctatgtg
    23761 accaatgccc taaacgatga tacgcctctg gccagccgtc gagtagtgca gaccatcctt
    23821 gaaagtgaca tgattgtcct agggccaggt tccctcttta cctctatttt gcccaatatc
    23881 gtgattaagg aaattgggcg ggctcttttg gaaactaagg cagaaattgc ctatgtctgc
    23941 aatatcatga cccaacgtgg ggagacggaa cactttacag atagcgacca cgtggaagtc
    24001 ttgcatcgtc accttggtcg cccttttatc gacactgtct tggtgaatat tgaaaaagtg
    24061 cctcaggaat acatgaattc caaccgtttt gatgaatact tagtgcaagt ggaacacgat
    24121 tttgtaggtc tttgtaagca agtttcgcgc gtgatttcat ctaacttcct tcgtctggaa
    24181 aatggcggtg ccttccacga tggagatttg attgtggacg agttgatgcg cattatacag
    24241 gtgaaaaaat gagtttcaca gtagcagtaa aagaagaaat cctgggccaa caccatctga
    24301 gccggcatga attatctgcc attatcaaaa tgtctggtag catcggtctc tcgacttcgg
    24361 gcttgacttt gtcagttgtg acagaaaatg ccaaactggc ccgtcacctc tatgagtcct
    24421 ttctccattt ctatgaaatc aaatctgaaa ttcgtcacca ccaacggagc aatcttcgca
    24481 agaatcgcgt ctataccgtt tttacagatg aaaaggtgca ggatttgtta agtgatttgc
    24541 acttggcaga ctctttcttt ggcctggaaa caggtattga tgaggcgatt ttatcggacg
    24601 aggaagcagg tcgtgcctat ctctgtggcg ctttcttggc aaatgggagc attcgtgacc
    24661 ctgagtcagg caagtaccag ttggaaatca gttctgttta tctggaccac gcgcaaggaa
    24721 ttgcctccct tctccaacag tttttactgg atgccaaggt gcttgagcgc aagaaggggg
    24781 ctgtgaccta tctccagcga gcagaagaca ttatggactt cttgatagta ataggagcca
    24841 tgcaggcacg tgatgatttt gagcgggtta agattttgcg agaaacccgt aacgacctca
    24901 atcgggctaa taatgccgag acagctaata tcgctcggac agtttctgcc agcatgaaga
    24961 ccattaacaa tatcagtaaa atcaaagata tcatgggctt agaaaatttg ccagtagatt
    25021 tgcaggaagt ggcgcaactg aggattcagc acccagacta ctctatccag cagttagcag
    25081 atagtctcag cacccctctg accaaaagtg gtgtcaatca cagactcaga aaaatcaata
    25141 agatagcgga tgaattataa aaccacgaat cctatgtgac tcgtggttct tttttataaa
    25201 ctggtagagt gttttggttg tactttttgt tcagggtcaa tgtagttgat agcgttgttg
    25261 acagcagttg gagcttctcc gaggcctgtc gcaatcagat caatttttcc gtcatagtag
    25321 cagcagtcac cgatagcata gatacctgct tggctggatt cctgtttgct gttgacgata
    25381 atcttgtgac ggttgaggtc gagcccccag tttttaaggt taccgacaga agatttgaaa
    25441 ccatagttga caaagaggtg gtctaggtca atggtttcag tttcatcaga tttgactttt
    25501 gtgatttcaa gtttatcaag tgtttttcca tttccaagga gttggctagg ggcgaatggt
    25561 gtcttgatgg ttacagatga ttcttgcaag gtttgaacac tgtgttccaa ggcacggaaa
    25621 ttatctctgc ggtgaacaag ggtagttggt gcgatttttt caaaagccaa agcccaatcc
    25681 acagccgagt ctcccccacc aagaatcgtc actttcttac cagcgtattg ctgaatgtta
    25741 gaaacgtggt agtggatatt ttcatagtcc tcaacccctt caagttccag cggacgtggt
    25801 ttgaaggcac cgccacccat agcgatgata actgttttag tcaggtgact tcctttggaa
    25861 gttgtgatgg caaattcttc ttcttgtttg tcaatctcaa gaaccgtttc attgagatga
    25921 ataggggtat caaatccatt tagctgttca atcaagcggt tagtcaactc ttctccagtc
    25981 aggtttggga agcctggtac gtctaggatt tccttttcag ggtagagaat agcaggttgt
    26041 ccacctagct ggggaagaga gtcgatgatt tgaaccttgg cttggcgtag gtgggcataa
    26101 aaggctgcaa aaagcccgac aggaccacca cccacaatgg taatatcata gagttgagac
    26161 atagtttctc ctttgttttt tctagtcagt ttattttatc atatttttgt tcaatgtaaa
    26221 atggactagg atagggaaaa aaatgccaga aaatggtata ataggacgaa agtgttttga
    26281 tagggaggat atcagggatg aattttcaac aattatccaa tctgcaatat tggaccagtt
    26341 tgtttgcaag tccatggacg atagctatca atctgattga tattttgatt gttgcttata
    26401 ttttatacca ttttacaaaa gctattgcag gaaccaagat tatgattttg gtacgtggag
    26461 ttttggtgtt tattttagct caaatccttg caaatatgat tggtttgact acgatttctt
    26521 ggttaatcaa tcaaattatt acttatgggg ttattgcggc ggttgttatc ttctctccag
    26581 agattcggac tggtttggaa cgtttgggaa gagcgacaga tttcttttcc aatgccccta
    26641 ttagtgctga ggaacagatg attcgtgcct ttgttaagtc tgttgaatac atgagtcctc
    26701 gtaaaatcgg ggccttggtt gctattcagc gtgtacgtac cttgcaggag tatatgtcga
    26761 caggaattcc cttggatgct aagatttctg cagaacttct cattaacatt tttattccca
    26821 acactcccct acatgacggt gcggtgatta tcaaagaaga acgtatcgct gtgacgtctg
    26881 cctatctgcc cttgacaaaa aacacaggga tttccaagga atttgggacc agacaccggg
    26941 cggctatcgg tttatcagaa gtctcagatg ccttgacttt tgtcgtatca gaggaaacgg
    27001 gaggaatttc gataacctat aatggaaggt ttaagcacaa cctaacactt gatgaatttg
    27061 aaacagaatt acgtgaaatc ttacttccaa aagaggaagt gggtcttagt tttaaagaac
    27121 gattgctagg aggatggaaa catgaaaaaa aatagtttat atatcatatc ctcactcttt
    27181 tttgcttgtg tcttatttgt ctatgctacg gcgacgaatt ttcaaaacag taccagtgct
    27241 aggcaggtaa aaacggaaac ctatactaat acagtaacca atgtccctat tgacatacgc
    27301 tataatagtg ataagtattt tattagcggt tttgcttcag aagtatcagt ggtcttgact
    27361 ggtgcaaatc gcctatcgct agctagtgaa atgcaagaaa gtacacgtaa attcaaggtt
    27421 actgctgacc taacagatgc cggtgttgga acgattgaag ttcctttgag cattgaagat
    27481 ttacccaatg ggctgaccgc tgtggcgact ccgcaaaaaa ttacagtcaa gattggtaag
    27541 aaggctcaga aggataaggt aaagattgta ccagagattg accctagtca aattgatagt
    27601 cgggtacaaa ttgaaaatgt catggtgtca gataaagaag tgtcgattac gagtgaccaa
    27661 gagacattgg atagaattga taagattatc gctgtcttgc caactagcga acgcataaca
    27721 ggtaattaca gtggttcagt acctttgcag gcaatcgatc gcaatggtgt tgtcttaccg
    27781 gcagttatca ctccgtttga tacaataatg aaggtgacta caaaaccagt agcaccaagt
    27841 tcaagcacat caaattcaag tacaagcagt tcatcggaga catcttcgtc aacgaaagca
    27901 actagttcaa aaacgaatta aaaatagaaa aggattttat aacaatgggt aaatattttg
    27961 ggactgatgg agtccgtgga gaagctaacc tagagctaac accagaatta gcctttaaac
    28021 taggacgttt tggaggctat gttcttagtc aacatgaaac ggaagcgccg aaagtctttg
    28081 taggacgtga cacacgtatt tcaggggaaa tgctggaatc ggccttggtg gcaggtctcc
    28141 tttcagtagg gattcacgta tacaaacttg gtgtccttgc aacaccagca gtagcttact
    28201 tggttgaaac tgaaggagca agtgccggtg tcatgatttc tgctagccac aacccagccc
    28261 ttgataacgg aatcaagttc tttggcggtg atggcttcaa actagatgat gaaaaagaag
    28321 cagaaattga agccttgcta gatgctgagg aagacactct tcctcgtcca agtgcagaag
    28381 gcttaggaat tttggtagat tatccagaag gcttgcgtaa gtatgaagga taccttgttt
    28441 caactggaac tcctcttgat ggaatgaagg ttgccttgga tacagctaat ggagcagctt
    28501 ctaccagtgc ccgtcaaatc tttgcagacc ttggtgccca attgacggtt atcggggaaa
    28561 caccagacgg tcttaacatc aaccttaatg ttggttcaac acatccagaa gcccttcaag
    28621 aagtggtcaa agaaagtggg tcagctattg gtttggcctt tgatggagac agtgaccgct
    28681 tgattgctgt tgatgagaat ggtgacatcg tcgatggtga caagattatg tacatcatcg
    28741 gaaaatacct ttctgaaaaa ggacaattgg ctcaaaatac aattgtgaca actgttatgt
    28801 ctaaccttgg tttccacaag gccttgaatc gcgaaggtat taacaaggca gttactgcag
    28861 ttggtgaccg ctacgttgtt gaagaaatga gaaaatcagg ttacaacctt ggtggtgaac
    28921 agtctggtca cgttatcttg atggattaca ataccacagg tgatggtcaa ttatcagcag
    28981 ttcaattgac taaaatcatg aaggaaactg gtaagagctt atcagagttg gcggcagaag
    29041 taacgattta tccacaaaaa ttagttaata tccgagtgga aaacgtcatg aaggaaaagg
    29101 ccatggaagt gccagctatc aaggccatca tcgagaagat ggaagaagaa atggcgggga
    29161 acggccgtat ccttgttcgt ccaagtggaa cagaacccct cttgcgtgtt atggcagaag
    29221 cgcctacaac agaagaagta gactactatg ttgataccat cacagatgta gttcgtgctg
    29281 aaattgggat tgactaaatc ctagaaaact agatgaaaat aaaaaattat ggtacaatag
    29341 cttataatat tgtagccgat ggagaaagac atgaatctta aacgtgaaca agaatttgtt
    29401 agtcagtatc attttgatgc gcgtaatttt gaatgggaaa atgaaaatgg agctcctgaa
    29461 accaaggtgg atgtgaattt ccaattgctc caacatgacc aagaaaatca agtgacttcc
    29521 ttgattgtca tcttgagctt tatgattgta tttgataagt ttgtcattag tggaacaatc
    29581 tcacaagtaa accatatcga tggccgtatt gtcaatgaac caaatgaatt gaaccaagaa
    29641 gaggtggaaa ccttggctcg tccatgtttg aacatgctca atcgtttgac ttacgaagtg
    29701 actgaaattg cattagactt accaggaatt aatttggagt tctaatatga aattagctgt
    29761 tttcacagat tcctctgctt atctcagtgc agagatcttg caaagagaag acttgtttgt
    29821 cttggatatt cctgtcaata ttgatggtga ggaatatgtc gaaggcatca atctgtctgc
    29881 tgaggaattt taccaaaaaa tggctcaggc ttctgaattg cctaagacca gtcaaccaag
    29941 tattgccaag ttagatgaga tcttaacttc gctcaaagaa caaggctata cacatgcctt
    30001 ggggcttttc ctatcttctg gaatttcagg tttttaccaa aatatccagt atatggtcga
    30061 tgactatgag ggcttaacca ttgctttccc agacactttg attacaagtg ctcccctagg
    30121 catcatggtt gaaagtgtct ttaattggcg tgatcagggc gatgattttg ccagcattca
    30181 ggataagcta gccattcaaa tcagccgtac gtcagccttt atcatggtag atgacttgga
    30241 tcatttggta aaaggtggac gcctttcaaa tggggctgcc attttgggca atttgcttag
    30301 cattaagcca atcctttatt ttaacgatca aggtgtgatt gaagtttacg aaaaagttcg
    30361 tactgaaaag aaggccacca agcgcttaat tgaaattatc aaggaaacaa cggcttcagg
    30421 tcaataccgg gtcattgtca ttcatgggaa tgctcctgaa aaggctgaag aattgcgtca
    30481 gcacttgctt gattttggct tgggttcgga tgtttcactt gctacatttg gtagtgtcat
    30541 tggaacgcac ctaggagcag gaagtattgc tctgggttat attccagtga tttagttggc
    30601 gcttctaggc tagttaagat gccttgtatc ttagaaattg aacacggact acctgcctct
    30661 tgaaaaaaga tgcctgtctt gcctttcgtg gaaagtcagt gccattccct atttttcaga
    30721 ggcagctaag gtcctttgta tcttgataat tgaacacgcc tggaaccctg tgtgaaaaag
    30781 atagttcttc caagaagtag acacttcttg attggaattc ctattttcac tttgtgttct
    30841 tacggacttt gtatcttaga caggagtaga gatgagtatt cgagtaatta ttgccggttt
    30901 taagggaaag atgggccagg ctgcttgtca gatggtattg actgatccag acttggactt
    30961 ggtggcagtt ttggatcctt ttgagtctga gtcagaatgg cagggtattc ctgttttcaa
    31021 ggataaggct gatttagctg gttttgaagc ggatgtctgg gtagatttta ctactccagc
    31081 tgttgcctac gaaaatacac gttttgctct tgaaaatggc tttgctccag tagttggaac
    31141 gactggtttc acgagtgaag aaattgcaga gctaaaagaa ttttctcgtg cccaagactt
    31201 gggtggcctg attgccccta actttgcctt gggtgctgtc ttactcatgc aatttgcgac
    31261 gcaggctgcc aaatatttcc caaatgtgga gattattgag ctccatcatg acaagaaaaa
    31321 ggatgctccg agtggaacag ccattaaaac agctgagttg atggcagagg ttcgagagtc
    31381 cattcagcaa ggtgcagcag atgaggaaga gctgattgct ggtgctcgtg gtgctgactt
    31441 tgatggtatg cgcatccact cagttcgttt gccaggcttg gtagctcatc aggaagtcat
    31501 ctttggcaat cagggagaag ggttgaccct ccgtcatgac tcctatgatc gcatctcctt
    31561 catgacagga gtcaatttgg gaattaaaga agttgtcaag cgtcatgagc ttgtctatgg
    31621 attagaacac ttattatgag attaatgcaa atgccttctg aatttcagaa ggctttacca
    31681 gtattagaaa aaattaaaga agcaggcttt gaggcttatt ttgttggggg ctctgttcga
    31741 gatgcccttc tccatagccc tatccacgat gtggatattg cgacgtcttc ttatccagaa
    31801 gagaccaagc agatttttcc gcgaacagcc gatatcggaa tcgagcatgg aaccgtcttg
    31861 gtcttagatg gggatgagga gtatgaggta acaacctttc ggacagagga tgtctatgtg
    31921 gactatcgca gacccagtgc ggtttccttt gtgcgctcgc tagaagaaga cctcaaacgc
    31981 cgtgatttca cagtcaacgc ctttgccttg gatgagacag gagaaatcgt tgacttgttc
    32041 catggtttag aagatttgga aaagcaagtc ttgcgagcag ttggagtggc tagtgagcgt
    32101 ttcaacgaag atgctttacg gattatgcgt ggtttccgtt ttcaggctag tcttggtttt
    32161 gcacttgagc cagaaacatt taaagctatg aagaccttga cgccgctttt ggagaaaatt
    32221 tctgtagagc gtaccttcgt cgagtttgat aaactcttgc tggctccatt ttggagaagg
    32281 ggcttggctt ccatgattga gagtcaagct tatgactatc tccctgatat ggcatctagc
    32341 caggacaagc tcaacagact gtttgatttg gagactgatt ttacttttga atcctctgaa
    32401 caagcctggg cggctttact atgggctttg gagattgaaa atgcgcagtc atttttgaaa
    32461 tcttggaaga cctcacgcca gtttgccaag caagttcagg atttgctgat tattttggct
    32521 ctgcgtgaaa atggagaatt gagtaagcgt gattgttatc gctttgactt ggatttactt
    32581 ttacaggctg aaaatcttcg tcaagctcag ggaaaagaag tcaacccaca agtcattaaa
    32641 gaaacctacc agagcttgac tattcatgat aagaaagaaa tccaaatcaa cggcggtatt
    32701 ttgatcaagg aatatggcta tcagccaggc ccagacttgg gagagatttt aacagagatt
    32761 gagtttgcca ttgtcgatgg agaattggag aataatcgtg aagccatcca tgcttacctg
    32821 agggagaaaa aatgagtgat tttatcgttg aaaaactaag taaatccgtt ggtgacaaga
    32881 ccgtttttag ggatatttcc tttattatcc atgacttaga cagaattggt ttaatcggtg
    32941 tcaatgggac tggcaagacc acccttttgg acgtcctttc tggtgtttct ggatttgatg
    33001 gggatgtcag tcctttttca gctaaaaatg attaccagat tggttacttg actcaggatc
    33061 ctgattttga tgatagaaag acagttttgg atacggttct atctagtgaa ctcaaggaaa
    33121 tccagctcat tcgtgagtat gaattgatta tgctcgacta tagtgaggac aagcaggcgc
    33181 gtttggaacg tgtcatggca gagatggact ctctccaagc ttgggaaatt gagagtcagg
    33241 tcaagaccgt tcttagcaaa ttgggcattc aagacttatc tactcctgtt ggggaattgt
    33301 caggtggtct gagaagacgg gtacagttgg cacaagtctt acttggcaac cacgaccttt
    33361 tgcttttgga tgagccgacc aaccatctgg atattgcgat tattgagtgg ctgaccctct
    33421 ttttgaaaaa ttctaagaag accgtccttt ttatcactca cgatcgttat ttcttagacg
    33481 ctttgtcaac acggattttc gagttggagc gagcaggctt gacagaatat cagggcaatt
    33541 accaggacta tgttcgcctt aaggcagaac aggacgagcg cgatgcagct ctacttcata
    33601 aaaaagaaca actctacaaa caagaactgg cctggatgcg cagacaaccg caggcacgtg
    33661 cgaccaagca acaagctcgt atcaatcgtt tccatgatct gaaaaaggaa gtttcaggca
    33721 gtagtgctga gacagacttg actatgaact ttgaaaccag tcggattggg aagaaagtca
    33781 tcgagtttca ggatgtttcc tttgcctatg aaaataagcc cattttgcaa aattttaatc
    33841 tcttagttca ggctcaagac cgtattggaa ttgttgggga caatggtgtt ggaaaatcaa
    33901 ccctacttaa cctgattgca ggaagtcttg agccgacagc aggacaagtt gtgattgggg
    33961 aaactgttcg catcgcctat ttctctcaac aaattgaggg tttggatgaa agcaagcgtg
    34021 tgatcaatta cctgcaggaa gtggcagagg aggtcaagac cagtggtggt tctacgactt
    34081 ccatcgctga gttgctggag caattcctct tcccacgttc gacgcatggg actttgattg
    34141 agaaattgtc agggggtgag aaaaaacgtc tttatctcct caaactgctt ttggaaaaac
    34201 caaatgttct tcttttagac gagccaacca atgacctaga tattgcaact ttgacagtct
    34261 tagagaattt cttgcaaggt tttgcaggtc ccgttttaac agtcagtcac gaccgctatt
    34321 tcttggataa ggtagcgacc aagattctcg cttttgagga tggcaagatt cgtcctttct
    34381 ttggtcatta caccgactat cttgatgaaa aagcttttga aacagatatg gccaatcaag
    34441 tgcaaaaggc cgaaaaggaa aaagtggtca aggttcgaga agacaagaaa cgcatgacct
    34501 accaagaaaa gcaggagtgg gcaagtattg aaggtgatat tgaaaccttg gaaaaacgta
    34561 tcgctgctat tgaagaggaa atgcaggcta acggctctga ctttggtaag ctggctactc
    34621 tccaaaaaga attggatgag aaaaatgaag cactccttga aaaatacgaa cgctatgagt
    34681 atctcagtga atttgatagt taagactatt cgaaaatcaa agtgcaaact atgtcggctt
    34741 cacattgccg actcaagtac agcctgtgac tggcttccta atttgcactt tgatttttat
    34801 tgagtataaa agaatagaaa aatcccgtct catgaaagga tttctctatt cttttttggt
    34861 ttcttgatga aagatatttt gccaggtttc gtggcgacgc cagatactgg tatggatgat
    34921 accatctaac tcatagcaga tgagtttggt tttttgactg atggaagtaa tttgaatgtc
    34981 cttgatagca gaatttaact cttttttggt cttataagcc tctttatcca tctgctctcc
    35041 atcttggcga atatagacaa aatcatcagt caagagttct tctagttggt ttccttggtc
    35101 aatcaattgt tcacgcataa gcaatttttt atagacattg tctaaaattt catcctcagg
    35161 gataggtgct ggttcgatat ggacatcggt atcaaagacg ccaaaacgct cctccagcat
    35221 agactcgacc tgatccgcga tttcatggct ttcaaaaaca gacaagtcag gattcatctc
    35281 tagtgtaata tccaggtaga tgttgctacc gtaggtgcga cctctttgcg atttgacctt
    35341 gctgattttg ggaatttcca tgatagcctt ttggtagtcc tcgagcaggc ggtcgtcaaa
    35401 gccatctgaa agactaaagg aagactcgat gaagatatca taggcagtct tcaagataaa
    35461 gaaagtgatg atgatagcaa ccagtttatc cacaatcgga taattaaaac tactagctag
    35521 gatggcaatg gcggttccaa gtgaggtaac agcgtcagaa agattgtcct tagcagctgc
    35581 cttcagcgcc ttggagttgg atttcttact gaggcgagta ttgtagagat agaccacaaa
    35641 cataatcgct gcagaaatga ttcctagagt tgcaccaaga ggatcaatga ccgtttcttc
    35701 ccgactgaga atcttttgaa tggtatctct tagaacatcg aaaccgacat agaacatgat
    35761 gatagaagtg atcaagcttg ccaaatcttc aatcttccaa tgaccaaaac ggtggtcacg
    35821 gtctgcaggc tggcgcgcca tccgaatccc gattaagagg gctacatttc caatgatgtc
    35881 cgatacgtta ttaaaaccat cggccaccaa actggatgaa tgaaggagat gaccagctgc
    35941 taatttggct gcagacaaga tcaaataggt cgaaatactg ataatggctc cacgctcagc
    36001 taacttgaga tttgagatag attgcttcat tcaacttcct ttctagtcac atagcattct
    36061 accattatac tggttttcaa ggaaaaattc aaataaggca gtttttactc tttgaaaact
    36121 ccccaaaatt tggtataatg gtactactca agggagtagc tggcagaaac ctgtgatagt
    36181 gtcgtcattc cgaattttat gctgaaaagt atgctttccg gccctatctt aaacagcgag
    36241 acttgttatg attaacaggt ctctttttgt ttgtcgtgaa aagatatgac agaaagagag
    36301 tctgttttgc acacaatgtc aaggaggaga cacatgtcaa aagaacaaaa acgccaagcg
    36361 ttttatactc agagccctga agaggtcttg caggctgtgg atgcgaccga gcaaggtttg
    36421 tcatcaagtg aggcggaaaa gcgccttgcc gaatttgggc acaatgaact cgaagaaggc
    36481 gagaaacgat caatcttggt caaattcatc gagcaattta aggatttgat gattatcatc
    36541 ctagttgcgg cagcaatctt gtcagtcgtg acttctggtg gggaagatat cgcagatgcc
    36601 attatcatcc tagctgtggt tatcatcaac gctgcctttg gtgtttacca agaaggaaaa
    36661 gctgaagaag ctattgaagc cctcaaatcc atgtctagtc cagttgcccg cgttcttcgt
    36721 gatggacaca tggcagagat tgactctaaa gaattggtac caggcgatat cgttgccctt
    36781 gaagcaggtg acgtggtacc agcggaccta cgtttgatag aagccaactc tcttaaaatt
    36841 gaagaagcag ccttgacagg tgaatctgta ccagtcgaaa aagacttgtc agtcgagctt
    36901 gcgacagatg ctggtattgg tgaccgtgtc aacatggcct tccaaaactc aaacgtaacc
    36961 tatggtcgtg ggatgggtgt tgttgtcaat acaggtatgt acactgaagt tggtcatatt
    37021 gctggtatgc ttcaagatgc ggatgagact gatacaccac tcaaacaaaa tttgaacaac
    37081 ctttctaagg tattgaccta tgctatcttg gtcattgccc ttgttacttt tgtagtgggt
    37141 gtcttcattc aagggaaaaa tccacttggt gagttgttga cttctgttgc ccttgccgtt
    37201 gcagccattc cagaaggact tcctgctatc gttaccatcg ttctttctct tggtactcaa
    37261 gttttggcca aacgacattc catcgttcgt aagttgccag cagttgaaac acttggttca
    37321 actgaaatca tcgcttctga taagactggt acgctgacta tgaacaagat gacagtcgaa
    37381 aaagtcttct acgatgcggt tctacatgac tcagctgatg atattgaact aggtcttgaa
    37441 atgccactac ttcgttcagt tgtcttggcc aatgatacga aaatcgatgt ggaaggtaac
    37501 ttgattggtg acccaaccga aacagccttt atccaatatg ccttggacaa gggctatgat
    37561 gtcaaaggtt tcttagagaa atatcctcgt gtagctgaat tgccatttga ctctgaccgt
    37621 aagctcatgt caacagttca cccattgcca gatggtcgtt tccttgtagc agtcaagggt
    37681 gcgccagacc aactcttaaa acgttgtctt cttcgtgata aggctgggga tattgctccg
    37741 attgatgaga aggttacaaa tctcattcat acaaacaatt ctgaaatggc tcatcaagcc
    37801 ttgcgtgtcc ttgcaggtgc ttataagatt atcgatagta ttccagaaaa tctcacttct
    37861 gaagagcttg aaaatgattt aatttttact ggtttgattg ggatgattga ccctgaacgt
    37921 cctgaagccg ctgaggctgt tcgtgtggct aaggaagcgg gaatccgtcc aattatgatt
    37981 acaggtgacc accaagacac agcggaagcc attgccaaac gtttgggaat cattgacgca
    38041 aacgatacag aaggtcacgt tttaactggt gctgaactca atgaactgtc agatgaagaa
    38101 tttgaaaaag tcgttggtca atactctgtt tatgcccgtg tgtctccaga acacaaggtt
    38161 cgtatcgtca aggcttggca aaaacaaggt aaagtcgttg ccatgacagg tgatggtgtc
    38221 aatgacgcgc cagctctgaa aacagccgat atcggtatcg gtatgggaat cactggtaca
    38281 gaagtttcta agggggcttc tgacatgatt cttgcagatg ataactttgc gactattatc
    38341 gtcgcagtgg aagaaggacg taaggtcttc tcaaacattc aaaagactat tcagtaccta
    38401 ctttctgcta atactgctga agtattaacc atcttcctat caaccttgtt tggttgggat
    38461 gtcttgcagc cggttcatct tttgtggatc aacttggtaa cggatacctt cccagctatt
    38521 gctcttggtg ttgaacctgc ggagcctggt gtcatgaatc ataaaccacg tggacgcaag
    38581 gcaagcttct tctcaggtgg tgttttgagt tctatcattt atcaaggtgt actccaagca
    38641 gctcttgtta tgagtgttta tggccttgcg attgcttacc cagttcatgt gggtgacaat
    38701 catgctattc atgcagatgc cctaacgatg gcctttgcaa cccttggttt gattcagctc
    38761 ttccatgcct acaatgtcaa gtctgtctac caatccatct tgacagttgg cccattcaag
    38821 tctaagacct ttaactggtc catcttggta tcctttatcc ttctcatggc aacaatcgtt
    38881 gtagaaccgc ttgaaggaat cttccacgta accaaactag acttgtcaca atggggaatt
    38941 gttatggctg gaagcttttc aatgattatc atcgtcgaaa tcgttaagtt tattcaacgc
    39001 aaactcggtt ttgacaaaaa tgcgatttaa gggaggtttc ggatgtcagc atatcaatta
    39061 ccgaccgtat ggcaggatga agctagtaat caaggagctt ttacggggct aaacagacca
    39121 acagcaggtg cccgtttcga acaaaacttg ccaaaaggag aacaagcttt tcagctttat
    39181 tcactgagaa caccaaatgg tgtgaaggtt actatcttat tggaagaatt actagaagct
    39241 ggttttaagg aagcggctta cgacttgtat aagattgcta tcatggatgg ggatcaattc
    39301 ggatcagact ttgtgaagct caatccaaat tccaagattc cagccttatt ggaccagtca
    39361 ggtactgaag atgtaagagt ctttgagtct gctcatattc ttctttacct tgctgagaaa
    39421 tttggagcct ttttaccaag taatcctgtg gaaaaggtag aagttttgaa ttggctattc
    39481 tggcaagcag gtgcagcacc ttttctaggt gggggatttg gacatttctt caattatgct
    39541 cctgaaaaat tggaatatcc tattaaccgt tttacgatgg aagtgaaacg ccagttggat
    39601 ttattggata aggaattggc tcagaaacct tatattgcag gcaatgacta tacgattgca
    39661 gatattgcta tctggtcttg gtatggacag ttagttcaag gaaatcttta ccaaggttct
    39721 gcaaaattct tggatgcctc aagttatcaa aatctagtaa aatgggcaga aaaaattgcc
    39781 aatcgtccag ctgttaagcg tggcttggaa gtaacttata cagaaattaa atagcaaaaa
    39841 agtcatcttc ggatggcttt ttgctacagt tgagggaaag ggtttgcagt tatcggcttt
    39901 tgtgctataa ttgctataat atagtaaaaa gcaagaggag tgtgaggaag tggaaaagaa
    39961 aattgtgaag gatatcttat ttttatctca agtgtctcag ccggcaagtc aggaggacct
    40021 ttatcttgcc agagatttgc aggatacact cttagcaaat cgtgatacct gtgttggtct
    40081 agctgccaat atgattgggg tgcagaagcg cgtgattatc tttaatcttg gcttggttcc
    40141 cgtggtcatg tttaacccag tgcttctgtc ctttgaagga tcttatgagg cagaagaagg
    40201 ctgtttgtcc ttggtaggtg tgagatcaac taagcgttat gaaaccataa ggcttgccta
    40261 tcgtgacagc aagtggcagg aacagaccat taccttgaca ggcttcccag ctcagatttg
    40321 ccagcatgag ctggatcact tggaaggacg aattatttag gaggaaagca aatgaaacga
    40381 atagtctttg aacttatttt tatcgcaacg acctggtata tctttttacc gccccttaac
    40441 ctgaccagct gggaatttct cttcttcctc tgtgggcatt tgttagttgt ggcaatctta
    40501 tttggctttg gcaaggggat aaaccttgtc aaaacggttc atgtgcgcca cggtaaggcg
    40561 gaagctgcct taaatcttga gggtttcaaa atcaatcggt tagggaaaat tctgttagct
    40621 tcgattggag gaattcttct cttggcagct ttggtttcct tggtaacttc tagcatgttt
    40681 caggctaaaa attatgccaa tgtagtcacg gttacggaaa aagactttac tgaatttcct
    40741 aagagtgaca ccagtaaggt tcctatccta gatagaagta ctgctgaaaa aattggagac
    40801 cgctacttgg gttccctaac cgataaggtg tcgcaatacg tagcggcaga tacctatacc
    40861 caattgacaa ttgatgggaa accttatcgg gtcacaccac tagaatatgc agaccctatc
    40921 aaatggttta acaatcaagc caagggaatt ggtgagtata tcaaggtgga catggtaact
    40981 ggaaatgcgg atttggtgga cttgaagaca ccaatcaagt attcagactc ggagtatttt
    41041 aaccgtgatg tcaaacgtca cctgcgcttg aagtacccga ccaaaatctt taaaactcca
    41101 tcttttgagg tggacgatga gggcaatcct ttctatgtag caacggttta ccaaaagcaa
    41161 tttggacttg ctgttcctcg tcctgcttca gtcattatct tggatgctac aaatggagaa
    41221 accaaggaat acagcttatc agatgttcca gaatgggtgg acaggatcta tccagcagag
    41281 gaaaccattg agcaaattaa ctacaacggc aagtacaagg acggtttctt gaatgccatg
    41341 atttccaaga aaaacgtgac ccagactacc aagggctata attacttgtc tatcggtaat
    41401 gacatctatc tctacacagg tgtgacgtcg gctaatgcgg atgagagtaa tcttggtttc
    41461 atccttgaaa atatgcgaac aggagaaatc actaagtata gcttggcttc tgcgacagaa
    41521 gaatcagccc gtgaatcagc agaaggtgct gttcaggaga aatcctacaa agcaaccttc
    41581 ccaatcctca tcaacctcaa tgacaagcct ctctacatca tgggcttaaa ggacaatgct
    41641 ggcttggtca aagagtacgc cctggtagac gcagtcgagt accaaaatgt tatcgttgct
    41701 actacagtgg aagagatgct cagcaagtat gccaataaaa acgaccttga aattgacaat
    41761 gcaacgacag aaagcatcaa gggagtagta gcagacctca aatcagctgt tatcaagggc
    41821 gacaccgtct acttctttaa agttgatggc aagatttaca aggttaaggc ctcagtatcc
    41881 gatgaccttc cttaccttga aaatggtaga accttcgaag gtcaagtagg aaaagacagc
    41941 tatctcaaga cctttaaagt acagtaatac tctgcgaaaa tctcttcaaa ccacgtcaac
    42001 tttatctgca acctcaaagc tgtgctttga gcaacctgcg gctagtttcc tagtttgctc
    42061 tttgattttc attgagtata aaaaaggttt atttaagaaa tatatgttat agtaaaataa
    42121 attaagacta atggaggaca aagaaatggg tttttatttg atggttgctt caatgctact
    42181 cggactgctc gctttgaaga taggtttttc tcagttcaag gagaacaaag ataaattctt
    42241 atctatctta acaagtttag ctgggctagc ccttgttctc gtggctgtct ggttaggatg
    42301 gcccaaataa atagaaaaac ctcggtcaaa ccgaggtttt tcagatgaat ttcttggttg
    42361 tggctaaaaa atatgctaca ctatcaatat gaagatttta atccctacag caaaagaaat
    42421 gaatacagac ttgccgagta tcgagacaac tcttttaaga tcagaaagtc aggctgtact
    42481 tgatgccttg gctctctatt ctgccagtca attggaaagt ttctacaagg tatcagctga
    42541 gaaggctgcg gaagaatgtc aaaatatcca agctttgaaa aggcaaactg ctcaacacta
    42601 cccagccttg aagctttttg atgggcttat gtaccgtcat atcaagagag acaaactgac
    42661 cgaggtagaa caagcctatc ttgaaaatca tgtcttcatt acctcggctt tgtacggagt
    42721 cgttccagcc ttgtcgccta tggcacctca ccgtttggat tttttgatga aattaaaagt
    42781 cgctggtaag actttgaaga gccattggaa ggcagcctat gatgaagctg tgaagcagga
    42841 agaagtgatt ttctctctct tgtcatcaga gtttgagact gtattttcta aggaaatcag
    42901 agcaaagatg gtgaccttca aattcatgga ggatagaggc ggtcagctga agattcactc
    42961 aactatctcc aagaaagcgc gcggggcctt tctaacagct ttaatagaaa atcaagtaca
    43021 aactgtgggg gaagcacgtc gcttgaactt tgctggattt gtttaccgag aagatttgtc
    43081 acaaccacag ggattggttt ttgtaaagga agtatagaaa tcagataaga gaaaagtcag
    43141 cacgattatg ctgacttttt tgataactta taaagtattg gacaaatgaa tctcatttga
    43201 taaggtgtta agatgattaa ccaaattcat gattgacaga tgatttcggc aaataaactt
    43261 cttggtaatc cctgaaatat agaaattaga cacgatgata tcgtaatctg tctgatttaa
    43321 aatctcagga cttgttttta attcatccca aatatcgaag gtaaagcggt tattacagta
    43381 ataggaaagc atatcaacaa aggtaaggga tatagcatgg tcaaagttac tgataatcaa
    43441 aaccttgata ggtggtcgat tttctaacaa ctgagtagag aggttttcag catgggttaa
    43501 gatggtgtac atcaagtgtt ccaactgttc aggatggtca tgctgtccaa ttgcctgacg
    43561 gtattgagcc agttcttgac gcgcacttcc cataaagtct gggaagtaaa cttcaaattt
    43621 tttaatcgtc aatgcttttt gttcaaataa gattggggta gaaaagattt cctgtctttc
    43681 aaagaaagca gtgttgtgta aatgccaaat cagctcatcg tggttagtaa aagtaatctt
    43741 atattgtttt gataggcgtt ctaatatttg actaagtaat tggtaagagt atcttgcttg
    43801 actgttatct tctaaagagt tgaagaattc ttgaggatct aggaaaatat cattctgaag
    43861 aaaagaaata aaaatttgag cgattgtatc tggagtcatt tcaagcccaa aatgtttaga
    43921 gaaataagca agtgtctcct ggaaatttgg aatgctcttt aaaagaggat aatattcttt
    43981 gtaaaagtgg ttggggaggt caatgaagtg accattttta accctgtgga tactgatagc
    44041 tatcatcagt ttgtacattc tataaattga aaatcgcatt ggataattcg tgattttata
    44101 gaagaagtca gcaaactctg ttaaatcttc ctcaggaagg tcaggaaaag gccaatctag
    44161 gaaataatag cgctcagaaa agtattgggc aaaaaagtaa cgaatatcga tctcatttcc
    44221 acgtatctcg gatggagtaa aagataattc aatttgaaac tgagatgaaa gaacctttgt
    44281 aatatttctg cccagtcgat agaggttggc actactaaag taaagatttt ctattgttcg
    44341 ataaataggt agcccctcat tgaagaacat atactctagt aattgaaaag attgagaatt
    44401 agcaagaaaa tattgataaa tatcttctac actagtgtta acttctaaat ctatcatgat
    44461 tccgttaaca gaagattgga tgttaataga tggaaaggca atacgtaatt catttaaatc
    44521 actttttaag attcgttctg tacatcctaa tttttcggct agttcatgta atttcatcca
    44581 attacgattc tgaattaggg tttccattaa gcgtaattgt ctttgaactt ttgtggataa
    44641 aaggtttctc atacgggtat ttcctccata attcattata tctttttttg tctaagtagt
    44701 ataaaaaaat tagagcaaga aaattgtcgt tagtaatcgg aaaaattaga ataatataag
    44761 tggcttttaa gtgcaaaaac agaatatatt aattgttcag aaaatattga ttaatgcctc
    44821 aaatagttgt acattgtaaa ctataaaata ctatctagga gtttaaaatg aaacattcac
    44881 ataaaaaatc atttgactgg tatagcatgc aacaacgtta ttctattcgt aagtattact
    44941 ttggtgcagt tagtgtcttg ctcggtaccg ctttggtatt aggtgcagca gctagtgtcc
    45001 aaacagtaca agcggaagaa aacaaacaag aaactaccaa tagtatttct gttggtaggg
    45061 gagaagcagc tactaaacca gcagaggttt ctgcgtctaa taaagagaaa acctatgcag
    45121 ctccaactgt agctaatcca gtagaaacga ctccagttaa aactggagaa gttactaaac
    45181 cagcagaaaa agttgaagaa gcaaaagaca aaaaagagga agtaacgcat caagatgcta
    45241 ttgacaagtc aaaattgtta acggctcttt cgcgtgctaa aaagttagaa agcaagttat
    45301 atacagaagc aagtgctgct aacttgcaaa caagtatcca agctggtcaa agcttgcttg
    45361 ggaaagcaga tgcatctgaa gctgaattat cagcagcaga gtcatctatt caatcatcta
    45421 ttattggtct agaacttcgt tctaactcta acaaaggaac tgtatcagaa acgcctgtag
    45481 caaagaaagc taatatagtt gaagcgaagg aagagactaa accagctgta acaacgactg
    45541 aacgttcagc tgttgatagc gctattttgc caattagcac agctgctaaa gtagaaacaa
    45601 cttcagctcc agcatctact aatgaaatct tgaaaccaag tttgagcctt tctgatgctc
    45661 gccaaaatcc agctatccgt aaggaagatg ttgatagagg gtatagtggt tttagaacag
    45721 caggaagtgg ctttagagcg gctggaagtg gttttagagc agctggacca gaaaataaac
    45781 caatcttaaa tccaaataat actattgcat tttctgacat cagtcagggc ttacattcat
    45841 ttcgtggtat aggacattca cgtggtggtc gtgaaatcca ttatgatgta acgacagtac
    45901 gtagaggtaa tagattgaat ttcacaatta aatactctgg tccaggtgaa tttgttaata
    45961 ataattttat cttggataaa ggggatggat ttggaaatcc ttcaaatgca acgatcacaa
    46021 gttcaaatcc aagagtaagg gagcaatcaa aatctattag tcagggtgcc aactacgtat
    46081 ctcactcagg atacagtatg acctctgcta cttcaacaaa tacggaacaa actatcagat
    46141 ttagtttgcc tatcattaat ccaaatggtg atttgtctgt tcgtttgaaa ccagttactt
    46201 ttaacgtgga ccaaggtggt ggtggtgccg ctactagcaa tgacccatac agtaactcca
    46261 actattatca tagagcaaat ccactcctct tggatgcaaa cccttatggt ggtactaata
    46321 ataagactgt ttcagaagac attgacttcc aaactgtcta tcttccaact agtaagttac
    46381 cagaaggtca aactagatta gttcgagaag gtgaaaaagg acaacgtcaa attacctata
    46441 aagtacatcg atttggtaac gaaacacttt taggattgcc aattagtaat agagttacta
    46501 aagaagctaa gccacgtatt atgcaaattg gtgtggctaa agagttaatc gatacagtaa
    46561 aaccacgtgt tgatcaaaat aaagttggtg atacaaataa cctcactttc tatcttgata
    46621 acgatggaaa cggtgtttat actgagggcg tagacgaact tgttcaaaaa attgctatta
    46681 aagatggagc caagggtgaa aaaggagacc aaggtgaacg cggtctaact ggagctaaag
    46741 gtgaaaaagg agaccgag
//
LOCUS       DBERCW010000013        45133 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.013, whole genome shotgun sequence.
ACCESSION   DBERCW010000013 DBERCW010000000
VERSION     DBERCW010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.013"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            261..491
                     /gene="blpU"
                     /locus_tag="ACL72M_000907"
     CDS             261..491
                     /gene="blpU"
                     /locus_tag="ACL72M_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGS0716061.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            494..619
                     /locus_tag="ACL72M_000908"
     CDS             494..619
                     /locus_tag="ACL72M_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS0716062.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            1027..1221
                     /locus_tag="ACL72M_000909"
     CDS             1027..1221
                     /locus_tag="ACL72M_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716063.1"
                     /translation="MKKVLKYFLVFVFLFLMNIFIFKILATLGFQLIMSEKSYIVLPL
                     FSLIVLYMIDKRIRKKKKSL"
     gene            1242..2135
                     /locus_tag="ACL72M_000910"
     CDS             1242..2135
                     /locus_tag="ACL72M_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0716064.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            2678..2974
                     /locus_tag="ACL72M_000911"
     CDS             2678..2974
                     /locus_tag="ACL72M_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HGS0716065.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            2981..4117
                     /locus_tag="ACL72M_000912"
     CDS             2981..4117
                     /locus_tag="ACL72M_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716066.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
     gene            4114..4596
                     /locus_tag="ACL72M_000913"
     CDS             4114..4596
                     /locus_tag="ACL72M_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HGS0716067.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            4593..5189
                     /locus_tag="ACL72M_000914"
     CDS             4593..5189
                     /locus_tag="ACL72M_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0716068.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            5170..5661
                     /locus_tag="ACL72M_000915"
     CDS             5170..5661
                     /locus_tag="ACL72M_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716069.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            6041..8194
                     /gene="comA"
                     /locus_tag="ACL72M_000916"
     CDS             6041..8194
                     /gene="comA"
                     /locus_tag="ACL72M_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGS0716070.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKANMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8207..9556
                     /gene="comB"
                     /locus_tag="ACL72M_000917"
     CDS             8207..9556
                     /gene="comB"
                     /locus_tag="ACL72M_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGS0716071.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9726..10433
                     /gene="purC"
                     /locus_tag="ACL72M_000918"
     CDS             9726..10433
                     /gene="purC"
                     /locus_tag="ACL72M_000918"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS0716072.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            10490..14215
                     /locus_tag="ACL72M_000919"
     CDS             10490..14215
                     /locus_tag="ACL72M_000919"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGS0716073.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14308..15750
                     /gene="purF"
                     /locus_tag="ACL72M_000920"
     CDS             14308..15750
                     /gene="purF"
                     /locus_tag="ACL72M_000920"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGS0716074.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15787..16809
                     /gene="purM"
                     /locus_tag="ACL72M_000921"
     CDS             15787..16809
                     /gene="purM"
                     /locus_tag="ACL72M_000921"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGS0716075.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16806..17351
                     /gene="purN"
                     /locus_tag="ACL72M_000922"
     CDS             16806..17351
                     /gene="purN"
                     /locus_tag="ACL72M_000922"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGS0716076.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17435..17944
                     /locus_tag="ACL72M_000923"
     CDS             17435..17944
                     /locus_tag="ACL72M_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS0716077.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17969..19516
                     /gene="purH"
                     /locus_tag="ACL72M_000924"
     CDS             17969..19516
                     /gene="purH"
                     /locus_tag="ACL72M_000924"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGS0716078.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQEFIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19638..20900
                     /gene="purD"
                     /locus_tag="ACL72M_000925"
     CDS             19638..20900
                     /gene="purD"
                     /locus_tag="ACL72M_000925"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGS0716079.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21157..21273
                     /locus_tag="ACL72M_000926"
     CDS             21157..21273
                     /locus_tag="ACL72M_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS0716080.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            21303..21791
                     /gene="purE"
                     /locus_tag="ACL72M_000927"
     CDS             21303..21791
                     /gene="purE"
                     /locus_tag="ACL72M_000927"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGS0716081.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21778..22851
                     /gene="purK"
                     /locus_tag="ACL72M_000928"
     CDS             21778..22851
                     /gene="purK"
                     /locus_tag="ACL72M_000928"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGS0716082.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVGEF"
     gene            22874..25261
                     /locus_tag="ACL72M_000929"
     CDS             22874..25261
                     /locus_tag="ACL72M_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS0716083.1"
                     /translation="MFEKIKGINIKSGIFEDETKLELFEGNFEGTNPVQNDRASLLFG
                     RNGSGKSTIARGINQLKNGEIGTDRVSFIDKNNNNIVLSDTERKSIFVFNEHYVDQKV
                     KIAQEGLDTIVILGEQVDIDEELDRLRTQLSESQIESQDYYAEYEEYLDEKNEKSPDF
                     WKKEMTDSLKGVGNWAERDREIKGNRAASPVHNNTFQNFVDLQPILDKNELEVEFNNK
                     KARYFSIRDSAVTINNELSLPDINFDSNELSTLLSEKIEEPELNSRDKYLLTLLSDST
                     KGERHLREVKDFFEDEHQKKCPFCTQSVSEDVKVELTNGITKLLSRAVEEHQSALRGK
                     KIDEINQDFSGYEQIDPILIQSYQNSINALNAKFNEINSIIDKKIDNPYNIVELPNIS
                     FSQELSQAEHDIEKINQAIIKHNSEISGIQKLKVDLLQINNELAFYEIQDAYKKFQEK
                     TNKKAICENNYNNSSKRVKDYEKQISDLEDKKLNIDIAVDEINKSLNYIFFSKNRLAI
                     QNQNGKYYLLSRGKSVVPSRVSVGERNALALCYFFTEIIQQRELADAYSHEYFIVIDD
                     PISSFDMENKVGITSYLKYCLTRFFKGNSNTRVLLMTHDKQTIYDFDIFLKEIMESCK
                     EEEGGQKSKYKKLELVSGKLQEFKTSTHDYTELLEIVFGYALGNSTPTSESFVGNAMR
                     KILEAYGSFNYKKGIAELTTDPLIVEKIDKEYRTYFENLMYRLVLNGESHFKDPVKTL
                     SIDFFDTISDEERKKTARDLLVLLYLLDDLHVLKHLEGVSNAENRLEQWKCEILE"
     gene            25434..26732
                     /gene="purB"
                     /locus_tag="ACL72M_000930"
     CDS             25434..26732
                     /gene="purB"
                     /locus_tag="ACL72M_000930"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGS0716084.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEINEIFNPIYYTKRVDDIFERLGLGD"
     gene            complement(26787..30725)
                     /gene="strH"
                     /locus_tag="ACL72M_000931"
     CDS             complement(26787..30725)
                     /gene="strH"
                     /locus_tag="ACL72M_000931"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGS0716085.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPRLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(31040..31756)
                     /locus_tag="ACL72M_000932"
     CDS             complement(31040..31756)
                     /locus_tag="ACL72M_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0716086.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            32104..33891
                     /locus_tag="ACL72M_000933"
     CDS             32104..33891
                     /locus_tag="ACL72M_000933"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGS0716087.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            33888..34364
                     /locus_tag="ACL72M_000934"
     CDS             33888..34364
                     /locus_tag="ACL72M_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0716088.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            34392..35297
                     /locus_tag="ACL72M_000935"
     CDS             34392..35297
                     /locus_tag="ACL72M_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS0716089.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            35284..36099
                     /locus_tag="ACL72M_000936"
     CDS             35284..36099
                     /locus_tag="ACL72M_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0716090.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALTLSALGHFALGM"
     gene            36106..36510
                     /locus_tag="ACL72M_000937"
     CDS             36106..36510
                     /locus_tag="ACL72M_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0716091.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            36808..37974
                     /locus_tag="ACL72M_000938"
     CDS             36808..37974
                     /locus_tag="ACL72M_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGS0716092.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKKLVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALDCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            38090..39127
                     /locus_tag="ACL72M_000939"
     CDS             38090..39127
                     /locus_tag="ACL72M_000939"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGS0716093.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            39334..40188
                     /locus_tag="ACL72M_000940"
     CDS             39334..40188
                     /locus_tag="ACL72M_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0716094.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            40338..40595
                     /locus_tag="ACL72M_000941"
     CDS             40338..40595
                     /locus_tag="ACL72M_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGS0716095.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADLVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(40637..40954)
                     /locus_tag="ACL72M_000942"
     CDS             complement(40637..40954)
                     /locus_tag="ACL72M_000942"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716096.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDRTDEVSNHIYGKVKLTWFEEI
                     FEEYKSPHNKTHTIKVFMYCPPKVRQKKSNFWGQYISIPDTMRFFNFKDFLQLLLTHI
                     KLF"
     gene            complement(41026..41304)
                     /locus_tag="ACL72M_000943"
     CDS             complement(41026..41304)
                     /locus_tag="ACL72M_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS0716097.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNA"
     gene            complement(41294..41449)
                     /locus_tag="ACL72M_000944"
                     /pseudo
     CDS             complement(41294..41449)
                     /locus_tag="ACL72M_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
     gene            41526..42290
                     /locus_tag="ACL72M_000945"
     CDS             41526..42290
                     /locus_tag="ACL72M_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGS0716098.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            42855..44234
                     /locus_tag="ACL72M_000946"
     CDS             42855..44234
                     /locus_tag="ACL72M_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS0716099.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            44248..44913
                     /locus_tag="ACL72M_000947"
     CDS             44248..44913
                     /locus_tag="ACL72M_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGS0716100.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
BASE COUNT        13001 a         8140 c        10125 g        13867 t
ORIGIN      
        1 cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt
       61 ttgcaggaag tctaatagta aaaaagtgat tagaaaacat cttttttaaa aatagagatg
      121 attttgaaac aaaaaagcta attcaagacg tttcgatgcc aattcaagat ttggatgaaa
      181 aaaattaata gatactgtta tactaaactt gtcaagtttg taacaagaca aatattaaaa
      241 ataaaaaaga ggtattcgtt atgaatacaa aaaagatgtc acaatttgaa attatggata
      301 ctgagatgct tgcttgcgtt gaaggtggcg gatgcaattg gggagatttt gccaaagcag
      361 gtgttggagg aggagcagta cgaggtcttc agctaggaat taaaacaaga acatggcaag
      421 gtgcagcaac tggtgctgcg ggaggagcta tacttggagg tgtggcctat gcagcgacat
      481 gttggtggta attatggatt ttaaaagttt tattattggt ttagtagttg gtatatttgg
      541 tccttatatg gatgatttaa ttagaaaaaa atttttaaag tcttcggaga agaaaacaga
      601 aaaatctgtt aaaaaataat caaaactata aatgatgaat ctgaatcaaa attattttgc
      661 gcatgtaaag aggagtctta tagtaacgag tcaaaaaagg agtaactatg aatcgtaatt
      721 tagaacggtg ttatctattc tgactaggaa tagatcatac cagaggtagc ttagaaatag
      781 cagagacatt agaaattgaa gtaataaata ggatgtcgta agtgttacta tcaatgattt
      841 atttgtttca agcttgccta gggtgacagt aaaaaatcaa tttcctttca tatcatattt
      901 ttagtagata ggatgtttgt tctgtctatt ttttgccaaa aaaagtgcag tcgaagtgtt
      961 tatttggagt tttatatata ttttcgataa aataggtgta gaaattagga aagttgaaga
     1021 aaagaaatga agaaggtttt aaaatatttt ttagtatttg tttttctatt tttgatgaat
     1081 attttcatct ttaagatact agcaaccctg ggatttcagc tgataatgag tgaaaagagt
     1141 tatattgttc taccgctgtt ttcgcttatc gttttatata tgattgacaa aagaattagg
     1201 aagaaaaaga aatctttgta atcaacttaa ggagtattac tatggatgag ttgaaacgtg
     1261 aaattggtta taaaatcaaa actattaggc gatcttgtgg aaaaactcag atagatattt
     1321 gtggtgatga atcagagttg acgattcgtc agctagcacg tattgaaaat gggcaagctt
     1381 tagcaacact tcctaaatta ttattgattg cggataaact tggagtatca ttacagaata
     1441 ttgtggatgt taaggttata gagattccaa aaggattcct aaaactcaaa gatgagctga
     1501 ttcattctca aacctacgct gataagggaa gaatcgaacg aaaagaagct atacttgagg
     1561 aaatatatga aaactattat gagaatttgc ctgaggaaga gcagttaatt gtggatgtga
     1621 cacaagctcg ttttgatatt tatggtagtt cagatgtgac ctacggttta gggttagtgg
     1681 aagaatattt ccagcagtta ttaaaaaaga aatatttttc tgtaaatgat ttgttgatta
     1741 ttgaattgta tttcttttgt tgtgctatgg gattagaaga taaagaacat tttgaggagt
     1801 tagctcaaaa agtattgcta tgttcagaat atgaagataa ggctagccta gttcaaatgg
     1861 aaaaagttct tctgagccta tttatccaaa ttcagacaga agatagtctg atatatattc
     1921 aaacatttga gaaaattatt gctaaaacaa gacatgtttt ttaccgacct catctatttt
     1981 tgctaaaggc aaaatatgct ttatttgtag acaagaatat tttagaggca gaaagtttct
     2041 atgaaaaggc gatttctcta gcagaattgc tagacgatca ggtattagtt cagagaattt
     2101 tagcagaaaa acagatagat ttcccaacaa cctgacttct aagtcaggtt gtttttttca
     2161 tgtttttgct atactaaacc tataaagaaa acgttctcaa aaagaaagga ggtttattat
     2221 ggttggaacg ttatttgtcc ttttaagtat aggagtctgg ttctatctat aatatcgggt
     2281 agagattaat ggaacaaggt attcttatat tggattaaag gaatgtttta ataggtttcc
     2341 tacattagta tagaggatga aactcaattt tcaatgatat agaagagtta tttggagatt
     2401 gtgagggttg agtatgttta tttatgatgt aggaagtgta aactaaaaag gaggtagtaa
     2461 tcgtataaaa gttaaataga cattatcttt tattgagtct tagtgatata aaagtaattt
     2521 gataatctag gaaaatgtag tagtaattta tttattatag atatgttaat aaaagtagta
     2581 taaaatatag acgaacattt gaagagagtt aggaatacaa catgtgcgaa ttaactctca
     2641 ataaaacata cataatatac aaaaggagta cactaaaatg aaatctaaaa gaatggaatt
     2701 tcataataaa tttcttattg tttcagcaat gttagcagtc attagttggt taagcttagg
     2761 tgttgtttct tttcctatgt tggctgggac attaggaatt tcgacaaaag ctgctgctac
     2821 tgtagtcaat ttgattagtg cttatagtac agttacagca gtaatttcaa ttgtaggtgc
     2881 aatcacagga gtaggttcta ttggttcggg tattgcagca acagttcttt atatattgaa
     2941 aaagaaaggt gctgctaaag cagctctatg gtagaactag atgaaaatac tttctaaaaa
     3001 agaatgtgaa agtattttag gttatcttaa ttttattggg ataacccttt tgttttttgt
     3061 tatcataagt ttgtcaatct attttaaaag ctatcttcct tttcaaggga aattattttt
     3121 actttttttg gtagtagatt acgctacttt gaatcgttat aatatgaaac tgcctatcca
     3181 aagtaaaaaa ataaatactt tctatataag gaaaaactat atttttctct atcttcttgc
     3241 cattgtcaag aaatattatt ctttccaaat tttacaatca ttcatttatt tatttatttt
     3301 gtattttcta gatattattg gatattttta tttatccatt actctttgtt tgatagctat
     3361 tcaaattatt tctttaattc tacctagttt gttttcaatt ataagtaaat tgttcttatt
     3421 tttatctata ggactattgt ctatagaaca aggacaagtt gtaatttatg tcatactact
     3481 caattatttt attttagtca tggggatatt agataatcat gcgagtaatt tctattttaa
     3541 aagcagtcga atgagtcaaa aaagatttcg tagcagtcta tttatattgc ttcgtttttg
     3601 ttggttaaat aaagggttaa ctttttcttt tattttgatt agtattcttc tttcctatct
     3661 attttggtat atgatgacga tgttatcaat tgatgacaca aaaataccaa tattatttct
     3721 ttatacctca atatatatta cattaatgga ggcaataata gggaatcata aatcctcaat
     3781 tggggtagat ctagctttac ttcaattatc tgctcttaat cattctaaaa tgaatttctt
     3841 ttttaagaat gcacaactaa tgatgttgac gcatttaatc tctttcttac aattttcatt
     3901 gttgttatgt ttgattccgg tgacaagtta tagtaatgat ataaaaagta ttttgttgaa
     3961 tttgttattg attccattca attattttat agcctatgtc tattataaga aagctctatt
     4021 tttaattaaa ggtacagtta gtttattgag atggagtttt ctggttttat attgttttct
     4081 gataatattt gtaattttag tagggggcat tagatgagaa aaagtggttt tctgatttac
     4141 tatgtgttat tttgtatagt ctgtttttta ctaggtttac ttttaagctt tatattaaaa
     4201 aatgagactt ttgctactat acctccgaaa ctggaattac aatttacatt gacagtttta
     4261 caggcaaatt ctacaaattt tttgctatat ctattctgtt ttccgatttc gcccttattg
     4321 caactttttg atttgctatc tttaggaata caattgggta tatctggtca gatgattgga
     4381 atagtagcta caataaaagg aatattacct catgctctta ttgaaatacc gaattttatt
     4441 tggtatcaag gtatgagtca gtatctttta taccgattat tgaaggatag gggaattaaa
     4501 aatatactta tttatataaa aagtaattta aaatggtata tcatttctta tcttttatta
     4561 attttagcag cgttgataga gggaattaaa ttatgaaaat tgaaaatgaa tctaaaagtt
     4621 atgataaatg tatattgaaa aatatatcac tagagattga taagggaatt tacagagttg
     4681 aaggagagaa tggttcagga aagagcaccc ttctacaact tttagctggg ctagagactt
     4741 ttgatagtgg tttaaagaat tgtgtctcca aagatgtact ataccttgat accaatcagc
     4801 ttggggttgt tccatttact atagaagaaa atttgcagtt gttgtgtgat tcttttcaaa
     4861 tccatctatc atttgaggat aaagaacaaa ttaatacttt ttttgataat aaaatcggag
     4921 ataactatat gacagcatct actggaacaa aattcaaatt aggcttatcc ttaatttttg
     4981 ctaaaaattg ggattatatt tttattgatg agactttatc aacagtggat gcaagaagta
     5041 ttgatatgat tgctaaacgc ttaatttcca tgaaagaaag ctctactatt atatatgtat
     5101 ctcataattt attgaatcaa gaattgatta gcaaatctca aaggatttta atagaggaag
     5161 gacgggttta tgaaatttca aacaaataat agtttataca aattaatgaa tctgattatt
     5221 tatctttttc ttttatattt gtttattgat ttactgatga agtcgggaat tttagatgaa
     5281 caaattgata aattatctga actatctaat ctttttacaa ttaaaataga aacaatattg
     5341 acagtgattt ctgttgtttt cacatttata gcaactctta ttgaatatgg attttctctc
     5401 tttctgatta cattattttt tgataagaat aagaggaact ttggagatat tcttttatct
     5461 aaaaatataa ccttaagttt tagcatttta ctttgttatt tatttaatcc atcggatata
     5521 aagtttgcct atttcagcgt attgacagta ttactaattg ggataacaaa ttatgcgaga
     5581 tttaaaaatt taagattgac agtagtgttt tctgtaccat ttttatttaa tgctataatg
     5641 tctattataa atagttttta gaaatactaa aatttttttc tttacttaat aatgatatga
     5701 aatcatttcg gttttgttaa cttgtaattc ttatattttc taggtagaac gtttgttctg
     5761 cctatttttt tatccaaaaa gtgcagttgg gagggagata ggctcatttg ggaaggaagt
     5821 ccagtttttg tttagtgatt ggggtaagat agttgttatc agatgagttt atactcttcg
     5881 aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat atatgtgact gacttcgtca
     5941 gtcctatcta caacctcaaa acagtgtttt gagcagcctg cggctagttt cctagtttgc
     6001 tctttgattt tcattgagta ttagggaaaa ggagatgaat atgaaatttg ggaaacgtca
     6061 ctatcgtccg caagtggatc agatggactg cggtgtagct tcattagcca tggtttttgg
     6121 ctactatggt agttattatt ttttggctca cttgcgagaa ttggctaaga cgaccatgga
     6181 tgggacgacg gctttgggct tggtcaaggt ggcagaggag attggttttg agacgcgagc
     6241 cattaaggcg aatatgacgc tttttgactt gccggatttg acttttcctt ttgttgccca
     6301 tgtgcttaag gaagggaaat tgctccacta ctatgtggtg actgggcagg ataaggatag
     6361 cattcatatt gccgatccag atcccggggt gaagttgact aaactgccac gtgagcgttt
     6421 tgaggaagaa tggacaggag tgactctttt tatggcacct agtccagact ataagcctca
     6481 taaggaacaa aaaaatggtc tgctctcttt tatccctata ttagtgaagc agcgtggctt
     6541 gattgccaat atcgttttgg caacactctt ggtaaccgtg attaacattg tgggttctta
     6601 ttatctgcag tctatcattg atacctatgt gccagatcag atgcgttcga cactagggat
     6661 tatttctatt gggctagtca tcgtctacat cctccagcaa atcttgtctt acgctcagga
     6721 gtatctcttg cttgttttgg ggcaacgctt gtcgattgac gtgattttgt cctatatcaa
     6781 gcatgttttt cacctcccta tgtccttctt tgcgacacgc aggacagggg agatcgtgtc
     6841 tcgttttaca gatgctaaca gtatcatcga tgcgctggct tcgaccatcc tttcgatttt
     6901 cctagatgtg tcaacggttg tcattatttc ccttgttcta ttttcacaaa ataccaatct
     6961 ctttttcatg actttattgg cgcttcctat ctacacagtg attatctttg cctttatgaa
     7021 gccgtttgaa aagatgaatc gggataccat ggaagccaat gcggttctgt cttcttctat
     7081 cattgaggac atcaacggta ttgagactat caagtccttg accagtgaaa gtcagcgtta
     7141 ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa tcctttacct atagtcgagc
     7201 agagagtcag caaaaggctc tgaaaaaggt tgcccatctc ttgcttaatg tcggcattct
     7261 ctggatgggg gctgttctgg tcatggatgg caagatgagt ttggggcagt tgattaccta
     7321 taataccttg ctggtttact ttaccaatcc tttggaaaat atcatcaatc tgcaaaccaa
     7381 gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa gtgtatctag tagcttctga
     7441 gtttgaggag aagaaaacag ttgaggattt gagcttgatg aagggagata tgaccttcaa
     7501 gcaggttcat tacaagtatg gctatggtcg agacgtcttg tcggatatca atttaaccgt
     7561 tccccaaggg tctaaggtgg cttttgtggg gatttcaggg tcaggtaaga cgactttggc
     7621 caagatgatg gttaattttt acgacccaag tcaaggggag attagtctgg gtggtgtcaa
     7681 tctcaatcag attgataaaa aagccctgcg ccagtacatc aactatctgc ctcaacagcc
     7741 ctatgtcttt aacggaacga ttttggagaa tcttcttttg ggagccaagg aggggacgac
     7801 acaggaagat atcttacggg cggtcgaatt ggcagagatt cgagaggata tcgagcgcat
     7861 gccactgaat tatcagacag aattgacttc ggatggggca gggatttcag gtggtcaacg
     7921 tcagagaatc gctttggcgc gtgctctctt gacagatgcg ccggtcttga ttttggatga
     7981 ggcgactagc agtttggata ttttgacaga gaagcggatt gtcgataatc tcattgcttt
     8041 ggacaagacc ttgattttca ttgctcaccg cttgactatt gctgagcgga cagagaaggt
     8101 ggttgtcttg gatcagggca agattgtcga agaaggaaag catgctgatt tgcttgcaca
     8161 gggaggcttt tacgcccatt tggtcaatag ctagaaagag gagaggatga aaccagaatt
     8221 tttagaaagt gcggagtttt ataatcgtcg ttaccataat ttttccagta gtgtgattgt
     8281 acccatggcc cttttgctcg tgtttttact tggctttgca actgttgcag agaaggagat
     8341 gagtttgtcc actagagcta ctgtcgaacc cagtcgtatc cttgcaaata tccagtcaac
     8401 tagcaacaat cgtattcttg tcaatcattt ggaagaaaat aagctggtta agaaggggga
     8461 tcttttggtt caataccaag aaggggcaga gggtgtccaa gcggagtcct atgccagtca
     8521 gttggacatg ctaaaggatc aaaaaaagca attggagtat ctgcaaaaga gcctgcaaga
     8581 aggggagaac cactttccag aggaggataa gtttggctac caagccacct ttcgcgacta
     8641 catcagtcaa gcaggcagtc ttagggctag tacatcgcaa caaaatgaga ccatcgcgtc
     8701 ccagaatgca gcagctagcc aaacccaagc cgaaatcggc aacctcatca gtcaaacaga
     8761 ggctaaaatt cgcgattacc agacagctaa gtcagctatt gaaacaggta cttccttggc
     8821 cggtcagaat ctagcctact ctctttacca gtcctacaag tctcagggcg aggaaaatcc
     8881 ccaaactaag gttcaggcag ttgcacaggt tgaagcacag atttctcagt tagaatctag
     8941 tcttgctact taccgtgtcc agtatgcagg ttcaggtacc cagcaagcct atgcgtcagg
     9001 gttaagcagt caattggaat cccttaaatc ccaacacttg gcaaaggttg gtcaggaatt
     9061 gacccttcta gcccagaaaa tcttggaggc agagtcaggt aagaaggtac agggaaatct
     9121 tttagacaag gggaaaatta cggcaagtga ggatggggtg cttcatctta atcctgagac
     9181 cagtgattct agcatggttg cagaaggtgc cctactagcc caactttatc catctttgga
     9241 aagagaaggg aaagccaaac tcacagccta tctaagttca aaagatgtag caagaatcaa
     9301 ggtcggtgat tctgttcgct atactacgac tcatgatgcc gggaatcaac tttttctaga
     9361 ttctactatt acaagtattg atgcgacagc tactaagact gagaaaggga atttctttaa
     9421 aatcgaggcg gagactaatc taacttcgga gcaggctgaa aaacttaggt acggggtgga
     9481 aggccgtcta cagatgatta cgggcaagaa aagttatcta cgttattatt tggatcaatt
     9541 tttgaacaaa gagtaatgtt cgtgttttta gagttaaata atttttaaac tgtgagaaag
     9601 attcttcttg cagttttttc tttacaattt ttgaaaaaca tctgctattt attcggttaa
     9661 attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga aaggcgaact
     9721 ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat acaactgagg
     9781 atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaat ggtgtcaaga
     9841 aggagcagat tgcaggtaag ggagtcttga ataatcagat ttcatctttt atttttgaga
     9901 aattaaatgc ggctggtgtg gcgactcact ttgtggagaa actttcagac acggaacaac
     9961 tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat actgctggtt
    10021 ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg attgtcgaat
    10081 tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat gtaaaattcc
    10141 tacagattgc ggatgaccag cagattgcct acttgaagga agaaacgcgt cgtatcaatg
    10201 aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt aagctagagt
    10261 tcggttttga caaggatggc aagattatct tggcagacga attttcacca gataactgcc
    10321 gcttgtggga tgctgatggc aaccacatgg ataaggatgt tttccgtaga ggattgggag
    10381 aactaaccga cgtttatgag attgtttggg aaaagttgca gggtttaaaa taacaacctc
    10441 aaggctgttt gggaatattg caagagctga aataaaggaa taagaattga tggataaacg
    10501 tatttttgtt gaaaaaaagg ctgattttca ggtcaagtca gagagtttgg ttagagagct
    10561 ccagcacaac ttgggactgt caagcttgaa aagtattcgt attgtgcaag tatatgatgt
    10621 atttgacttg gttgaggact tgtttgcacc tgcagagaag cacattttct ctgagcaggt
    10681 aaccgaccat gttttagatg aagtatctgt gcaggcggat cttgctaact atgctttctt
    10741 tgccattgaa agtctaccag ggcagtttga ccagcgtgca gcttcgtcac aggaagcctt
    10801 gcttttgttg ggaagttcga gtgacgtgac agtcaacaca gcccaacttt acttggtgaa
    10861 taaagatatt gatgcgactg agttggaagc tgtcaaaaac tacctgctca atccagttga
    10921 ttctcgtttc aaggatatca cgatagggat tgccaagcag gagttttcag agtcagacaa
    10981 gaccattcca aaattgcctt tctttgaaag ctatacagca gaagactttg ctcgctacaa
    11041 ggccgaacaa gggatggcca tggaagtgga tgatttgctc tttatccaag actactttaa
    11101 gtcaatcggg cgcgtgccaa ctgagactga actcaaggtt ttggacactt actggtctga
    11161 ccactgccgt catacgactt ttgagacaga gttgaaacac atcgactttt cagcttctaa
    11221 atttcaaaag caattgcagt caacctatga caagtatatt gccatgcgcg aggaattagg
    11281 tcggtctgaa aaaccacaaa ccttgatgga tatggcgact attttcggtc gttatgagcg
    11341 tgctaatgga cgattggatg atatggaagt ctctgacgaa atcaatgcct gctcagttga
    11401 aattgaagtg gacgttgatg gtgtcaagga accttggctc ctcatgttta aaaacgaaac
    11461 tcacaaccat ccaacagaaa ttgagccatt tggtggagcg gctacctgta tcggtggagc
    11521 tattcgtgat ccgttgtcag gccgttccta tgtttaccaa gccatgcgta tttcaggtgc
    11581 tggtgatatt acagcaccga tttcggaaac tcgtgctggg aaattgccac aacaagtcat
    11641 ttctaaaaca gcaactcatg gttattcttc atatggtaac cagattgggc ttgccacaac
    11701 ctacgttcgt gaatacttcc acccaggctt tgtagctaaa cgtatggaac ttggtgccgt
    11761 tgttggtgcg gctcccaagg gcaatgttgt ccgtgaaaaa cctgaagcag gtgatgtgat
    11821 catccttctc ggaggtaaaa caggtcgtga tggtgtcggt ggtgcgacgg gctcttctaa
    11881 ggttcaaaca gttgagtctg tagagactgc tggtgctgag gttcaaaaag gaaatgccat
    11941 cgaagaacgc aagattcagc gcctcttccg taatggcaat gtcactcgtc tgatcaagaa
    12001 gtccaatgac tttggggcag gcggtgtctg tgtggctatc ggtgaattgg cagacggtct
    12061 tgaaatcgac ctcaacaagg tgcctcttaa ataccagggc ttgaatggta cagaaattgc
    12121 catctctgaa tcacaagaac ggatggcggt cgtggttcgt cctgaagatg tggatacctt
    12181 cgttgccgaa tgtaacaaag aaaatattga tgctgttgtg gtggcgacag taactgaaaa
    12241 accaaatctt gtcatgcact ggaatggtga gacaatcgtt gacttggagc gtcgtttcct
    12301 tgacatcaat ggtgtgcgcg tggttgtcga tgccaaagtt gtggacaagg atgtcaaact
    12361 cccagaagag cgtcaaacat ctgctgaaac actggaatca gataccctta cggttctatc
    12421 tgacctcaac catgcaagtc aaaaaggatt acagactatc tttgactgct ctgttggacg
    12481 ctcaacggtt aatcacccac ttggtggtcg ttaccaactc acaccaactg aggcatctgt
    12541 gcagaaattg ccagttcaac acggtgtgac tcatactgcg tcggtcattg ctcaaggttt
    12601 caacccatat gtagctgaat ggtctccata ccacggtgct gcttatgcgg ttatcgaagc
    12661 aactgctcgt ttggtggctg ctggtgccaa ctggtccaag gctcgtttct cttaccaaga
    12721 atatttcgag cgtatggaca agcaagcaga gcgttttggt cagccagtag ccgctcttct
    12781 aggctctatt gaagctcaga ttcaacttgg cttgccatct atcggtggta aggactccat
    12841 gtctggtacc tttgaagaat tgaccgttcc gccaaccttg gttgcctttg gggtgacgac
    12901 ggcagatagc cgtaaggtgc tctctccaga atttaaagct gttggggaaa atatctacta
    12961 catcccaggt caagccctct ctgcagagat tgattttgac ttgattaaga aaaattttgc
    13021 tcagtttgaa gcaagccaag ctgaccataa agtgacatct gcatcagctg tcaaatacgg
    13081 tggtgtagtt gaaagtttgg ctcttgctac ctttggaaac tatattggtg cagaggtgac
    13141 cttgcctgaa cttaaaacag ctttgacagc tcaattaggc ggctttgtct tcacatctcc
    13201 tgaagaaatt gctggagtag agaagattgg acaaacgaaa gcagacttta cactgactgt
    13261 caacggtgtg aagctagatg gacacaagct tgacagtgca tttcaaggga cattggaaga
    13321 agtttaccca acagaattta cccaagcgaa agaactagaa gaagtaccag ctgtggcatc
    13381 agatgttgtg attaaagcca aagaaaaggt tgaaaaacct gtggtttaca tcccagtctt
    13441 tccaggaacc aactcagaat atgattcagc taaggccttc gaaaaagaag gtgcagaggt
    13501 caatttggtg ccattcgtga ccttgaatga agaagctatt gtcaagtcag ttgaaactat
    13561 ggttgacaat atcgacaaga ctaatattct cttctttgct ggtggattct cggctgcgga
    13621 tgaaccagat ggttcagcta agtttatcgt caatatcctg cttaatgaaa aagtgcgtgt
    13681 ggctattgat agctttatcg cccgtggtgg tttgattatc ggtatttgta atggattcca
    13741 agccttagtc aaatcgggtc tcctacccta cggaaacttt gaagatgcta acaatactag
    13801 cccaaccctc ttctacaatg atgccaacca acacgtggcc aagatggtgg aaactcgcat
    13861 tgccaatacc aactcaccat ggttggctgg tgtgcaagtg ggcgatatcc acgctattcc
    13921 tgtttcgcac ggtgaaggga agtttgtcgt gacggctgag gaatttgcag agctccgtga
    13981 caatggacaa attttcagcc aatacgttga ctttaacggt aaaccaagta tggattctaa
    14041 gtacaatccg aatggttctg tccatgccat cgaaggaatt accagcaaga atggtcaaat
    14101 catcggtaag atgggccact cagaacgtta tgaggatggt cttttccaaa atatcccagg
    14161 caataaagac caacacctgt tcgcatcagc ggttaaacat ttcactggaa aataagactt
    14221 acagattttc taatagatag tatcagtaat gtaaaagtca tgtaaatcta gctcttgatg
    14281 attacaaatg aaaattaggt ataaaaaatg acatacgaag taaaatctct taatgaagaa
    14341 tgtggtgttt tcggtatttg gggacatcca gatgctgcta agttgaccta ttttggactc
    14401 cacagtcttc aacaccgtgg tcaggagggg gcaggaatcc tctccaatga tcaaggacaa
    14461 ctgaagcgcc atcgtgacat ggggctttta tcagaagttt tcagaaatcc agccaatttg
    14521 gataaattga caggagctgg tgcgattggg catgtgcgtt atgcgactgc tggcgaagct
    14581 tctgttgata acatccagcc cttcctcttc cgttttcacg atatgcagtt tggcttggct
    14641 cataatggaa atctgaccaa tgcagcctct ctcaagaaag aactggaaca aagaggagca
    14701 attttcagcg cgacttcgga ctctgaaatc ttggctcacc tcattcgtcg cagtcataat
    14761 cctagcctga tgggcaaaat caaggaagcg ctcagccttg tcaaaggtgg ttttgcctat
    14821 atcttgctgt ttgaggacaa gttgattgcg gctcttgacc ctaatggctt tcgtccgctt
    14881 tctatcggga aaatggccaa cggagcggtg gttgtttcct ctgaaacctg tgcttttgag
    14941 gtcattggtg ccgagtggat tcgtgatttg aagccaggtg agattgtgat cattgatgac
    15001 gagggcattc agtatgacag ctatacagat gatactcagt tggcgatttg ttctatggag
    15061 tatatctact ttgctcgccc tgattctaat atccacggtg tcaatgtcca tacggcacgt
    15121 aagagaatgg gagcgcaatt ggcgcgagaa tttaagcatg aggcagatat tgtagttggt
    15181 gtgcccaatt cttccctaag cgcggctatg ggatttgcgg aagaatcagg cttaccaaat
    15241 gaaatgggtc tgatcaaaaa ccaatacacc cagcgaactt ttatccaacc gactcaagaa
    15301 ttgcgggagc aaggagtgcg gatgaaactg tctgctgttt cgggtgttgt caaaggcaaa
    15361 cgtgtggtca tggtggatga ttccattgta cgtggaacaa cctctcgtcg tatcgttcag
    15421 ctcttgaaag aagcgggtgc gactgaggtt cacgttgcca ttggaagtcc tgcactagcg
    15481 tatccatgtt tctacgggat tgatatccag acccgtcagg agctgattgc agccaatcat
    15541 acggtcgaag aaactcgcca aatcattggt gcggacagtc tgacttatct ttcaattgat
    15601 ggcttgattg agtcgattgg tatcgaaaca gatgcgccga acggtggtct ctgtgtcgct
    15661 tactttgacg gtgactaccc aacgcctctc tatgactacg aagaagacta tcgtagaagt
    15721 ttggaagaaa agaccagttt ttacaagtag gcgacagatt ctccattaaa gaaaaggaaa
    15781 aaacaaatga caaataaaaa tgcatatgcc cagtcgggtg tggatgttga agcgggttat
    15841 gaagttgttg aacggattaa aaagcacgtg gcccgtacgg agcgtgcagg tgtcatggga
    15901 gctcttggtg gctttggtgg tatgtttgac ctttccaaga ctggggttaa agaacccgtc
    15961 ttgatttcag ggactgacgg tgtcggaacc aagctcatgt tggctatcaa gtacgacaag
    16021 cacgatacca tcgggcagga ctgtgtggcc atgtgtgtca acgacatcat tgctgcaggt
    16081 gcggaacccc tctattttct cgactacgta gcgacaggga agaatgaacc agctaagcta
    16141 gaacaagtgg ttgctggtgt ggcagaaggt tgtgtgcagg ctggtgctgc cctcatcggt
    16201 ggggaaacgg ctgaaatgcc gggcatgtac ggcgaagacg actatgactt ggctggtttt
    16261 gcggtcggtg tggctgaaaa atctcaaatc attgacggtt caaaggtggt agagggagat
    16321 gttcttctcg gacttgcttc aagtgggatt cactcaaatg gttactcttt ggttcgtcgt
    16381 gtctttgcgg attacacagg tgaggaagtc ctaccagaat tggaaggcaa gaaacttaag
    16441 gaagttctac ttgagccgac tcgtatctat gtcaaggctg tcttgccgct catcaaagaa
    16501 gagttggtca acggcattgc ccacatcaca ggtggtggct ttatcgaaaa tgtccctcgt
    16561 atgtttgcag atgacctagc tgctgaaatt gatgaaagca aagttccagt gcttccaatt
    16621 ttcaaagccc ttgaaaaata tggtcagatt aaacacgaag aaatgtttga aatcttcaat
    16681 atgggtgtgg gacttatgtt ggcggtcagc cctgaaaatg tagagcgtgt aaaagaattg
    16741 ttggatgaag cagtctatga aattggtcgc atcgtcaaga aagaaaacga aagtgtcatt
    16801 atcaaatgaa aaaaatagcg gtttttgcct ctggtaatgg ctcaaatttt caggtgattg
    16861 ccgaagaatt tccagtggag tttgtctttt cagaccatcg tgatgcctat gtgcttgagc
    16921 gtgcaaagca gctcggcgtt ctgtcctatg cttttgaact caaggagttt gagagcaaga
    16981 cagactacga agcagccctt gtcgaactct tggaagaaca ccagattgac ttggtttgcc
    17041 tagcaggcta catgaaaatc gttggaccaa ccttattgtc ggcttatgaa ggtcggattg
    17101 tcaacattca tccagcctac ttgccagaat ttccaggagc tcatgggatt gaggatgctt
    17161 ggaatgctgg cgtgggtcag tctggtgtga ccattcactg ggtggattcg ggtgtggata
    17221 caggccaggt catcaaacag gttcgtgtgc cacgactagc tgatgatacc attgacagat
    17281 ttgaagctcg catccatgaa gcagagtaca ggttgtatcc ggaagtagtg aaggctctat
    17341 ttacagattg actttttgat gattcatatg atatctttga ttttaaattg gagtcagtgt
    17401 ttgttgaaga cggcttcaaa cggaggtatt tgtaatgtta gaatctaaaa aaacaactcg
    17461 atatgtattt tatgtctatc tgatgttatt aacttgggga atcttattta agtttgaaac
    17521 aaatcctgaa tttatagcat ttttcttagc tccaaggtat atcaattgga ttccattttc
    17581 agaaccacta atagtcgatg gaaaaattgt ttttgctgaa atgttattta atctgatttc
    17641 ctttattcca ttaggtgttt gtttcccttt gataaaaact aatttatcta gtttaagaat
    17701 agtcgggaca ggtttcttga ttagtttatt gtttgagtgc ttacagtata ttttagcaat
    17761 aggtataaca gatataacgg atttgacttt aaatacgcta ggtgtctgtg taggcttact
    17821 gatttatcaa atttttataa gagtgttcaa atcacagact agaaaatgga tcaatatctt
    17881 aggtatgctt agccttggtt ttgcttatct tgttttactg ttactgcatt taattggtgt
    17941 ttaactaatg attaaaaagg agaatataat gactaaacgc gtcttaatca gcgtctcaga
    18001 caaagcgggc attgttgaat ttgcccaaga actcaaaaaa cttggttggg agattatctc
    18061 aacaggtgga actaaggttg cccttgataa tgctggggtg gataccattg ctatcgatga
    18121 tgtgactggt ttcccagaaa tgatggacgg tcgtgtgaag accctccacc caaatatcca
    18181 cggagggctt ctcgctcgtc gtgacttgga tagccacttg gaagcggcta aggacaacaa
    18241 gattgagctc attgaccttg tggtggtcaa cctttaccca tttaaggaaa ctatccttaa
    18301 accagatgtg acttatgctg atgcagttga aaatatcgat attggtgggc cgtctatgct
    18361 tcgttcagca gcgaaaaatc atgccagtgt tacagttgtg gtagatcctg ctgactacgc
    18421 tgtggttttg gacgaattgg cagcaaacgg cgaaacctct tatgaaactc gccaacgttt
    18481 agcagccaaa gtatttcgtc acacagcggc ttatgacgcc ttgattgcag aatacttcac
    18541 agctcaagtg ggtgaaagca agcctgaaaa actcactttg acttatgacc tcaagcaacc
    18601 aatgcgttac ggtgagaatc ctcaacaaga cgcggacttt taccagaaag ctttgcctac
    18661 agattactct attgcttcag ccaaacagct caacgggaaa gaattgtcat ttaataatat
    18721 ccgtgatgca gatgctgcta tccgtatcat ccgtgacttc aaagatagtc caaccgttgt
    18781 ggctctcaaa cacatgaatc catgtggaat tggtcaagct gatgacatcg agactgcttg
    18841 ggactacgct tatgagtctg acccagtatc tatctttggt gggattgtcg tcctcaaccg
    18901 tgaggtggat gctgcgacag ctgagaagat gcacggcgtt ttcctcgaaa tcatcattgc
    18961 accaagctat acggatgaag cgctagctat tttgatcaat aaaaagaaaa acttgcgtat
    19021 ccttgccttg ccatttaatg ctcaagaggc tagcgaagtg gaagcagaat acacaggtgt
    19081 agtcggtgga cttctcgtgc aaaatcaaga cgtggtcaag gaaagcccag ctgactggca
    19141 agtggtgacc aaacgtcagc caactgagac agaagcgact gctcttgagt tcgcttggaa
    19201 ggctatcaag tacgtcaaat caaatggtat tatcgtgacc aacgaccaca tgacacttgg
    19261 tgttggtcca ggtcaaacca accgtgtggc ttctgttcgc cttgccattg accaagccaa
    19321 agatcgtctg aacggggcgg tccttgcttc agatgccttc ttcccatttg cggataacgt
    19381 ggaagaaatc gccaaagcag gaattaaggc catcatccag cccggtggct ctgtccgtga
    19441 ccaagaattc atcgaagcag cggataaata cggcttgact atggtcttta caggtgtgag
    19501 acattttaga cattaagaag ataaaaggga agaaaacagt ttctttcctt ttttggctta
    19561 aaatgctaac tgaaacaaga ttaaaacgaa cttttttgat ataatgttgg taaataattc
    19621 gcaaaagagg ttgaggaatg aaactgcttg ttgtcggttc tggtggtcgt gagcatgcga
    19681 ttgctaaaaa gttacttgaa tcaaaagacg tggaaaaagt ctttgtagct cctgggaatg
    19741 acggtatgac tctggatggt ctggaattgg taaatatatc tatttccgaa cattataaat
    19801 tgattgactt cgcaaaggcc aacgatattg cttggacctt tatcggtcca gatgacgccc
    19861 ttgcggctgg tatcgtggat gatttccatg cagctggtct caaagccttt ggtccgacaa
    19921 gattggcagc ggagctggag tggtccaagg atttcgccaa ggaaatcatg gtcaaatatg
    19981 gtgtttcgac agcagcctat ggcacatttt cagatttcga ggaagcaaag gcctatatcg
    20041 aaaagcatgg tgcgcctatc gtagtcaagg cggatggctt ggcgcttggg aagggtgtcg
    20101 tcgttgctga gacggttgag caagcggtcg aagccgctca tgagatgctt ttggacaata
    20161 aatttggtga ctcaggtgcg cgcgtggtta ttgaggaatt ccttgaagga gaggaatttt
    20221 cactctttgc ctttgtcaat ggtgataagt tctacatcat gccaacggct caggaccaca
    20281 aacgtgccta cgatggcgac aaagggccta acacgggtgg tatgggtgcc tatgcgccag
    20341 ttccacactt accacagagt gtagttgata cagcggttga caccattgtc aagccagttc
    20401 tagaagggat gattaaagaa ggtcgccctt atctgggagt tctttacgca gggcttatcc
    20461 tgacagctga tggaccgaaa gtcattgagt tcaacgctcg gttcggagat ccagaaactc
    20521 agattatctt gcctcgcttg acctctgact ttgctcaaaa tatcacagat atcctggata
    20581 gcaaggagcc aaatatcatg tggacggaca agggtgtgac tctgggtgtg gttgtcgcat
    20641 ccaagggcta cccgctagac tatgaaaggg gcgttgagtt gccagccaag acagaaggcg
    20701 atgtcatcac ctactatgca ggggctaagt ttgcggaaaa tagcagagca ctgctctcaa
    20761 acggcggacg agtttatatg ctcgttacca cagcagatac cgtcaaagaa gcccaagcca
    20821 gcatctacca agaactatcc caacaaaaaa tagaaggact cttctaccga acagatatcg
    20881 gaagcaaggc aattaagtaa agatataaga ataacgcgcc gtagtcgcca aacacgataa
    20941 tggtcgtcgt ggtgaaaaga ccagaacagt gaatgttctg gtcaggggga aacttggaga
    21001 ccgtaggctc aaagtttagg aatgaaaccg aaggtttgct tccgcctcca tcacctaaga
    21061 ccattatcaa aaagaaaaat aaaaattcac aaaatacgtt aatgatcgta tggtttgcga
    21121 gcgttagcga gctaatatag aacaatcacc gccgttgtga aagaacgatt ggatgataat
    21181 ccaatcgttc agggaaattg gaagaccttg ggtttccaat ttaggcatga gacacctttg
    21241 gtggctgctg ccgtccctca caagctaagg tgattgttga aaaagaggaa aaaggagaag
    21301 aaatgaaacc agtaatttcc atcatcatgg gctcaaaatc cgactgggca accatgcaaa
    21361 aaacagcaga agtcctagac cgcttcggtg tagcctacga aaagaaagtt gtttccgcac
    21421 accgtacacc agacctcatg ttcaaacatg cagaagaagc ccgtagtcgt ggcatcaaga
    21481 tcatcatcgc aggtgctggt ggcgcagcgc atttgccagg catggtagct gccaaaacaa
    21541 cccttccagt cattggtgtg ccagtcaagt ctcgtgctct tagtggagtg gattcactct
    21601 attctatcgt tcagatgccg ggtggggtgc ctgttgcgac catggctatc ggtgaagctg
    21661 gagcgactaa cgcagctctc tttgccctcc gtctcctctc tgtagaagat aagtccattg
    21721 cggatgcact tgccaacttt gctgaagaac aaggaaaaat cgcagaggag tcgtcaaatg
    21781 agctcatcta aaacaatcgg aattatcggt ggcggtcaac tgggtcagat gatggccatt
    21841 tctgctatct acatgggcca caaggttatc gcgctggatc ctgcggcgga ttgcccggcc
    21901 tctcgcgtgg cggaaatcat tgtggcacct tataacgatg tggacgccct ccgtcagttg
    21961 gcagaccgtt gcgatgtcct cacttatgag tttgaaaatg tcgacgctga cggtttggat
    22021 gccgttatca aggatggaca actccctcaa ggaacagatc tgctccgcat ttcgcaaaat
    22081 cgtatttttg aaaaggactt tttgtcaaac aaggctcaag tcactgtggc accctacaag
    22141 gtcgtgactt ctagcctaga cttggcagat atcgacttgt cgaaaaacta tgtcctcaag
    22201 actgcgactg gtggctacga tggtcatgga caaaaggtta ttcgttcaga agcagacttg
    22261 gaagcagcct atgcgctagc agactcagca gactgcgtct tggaagaatt tgtcaacttt
    22321 gaccttgaga tttctgtcat cgtgtcagga aatggcaagg aggtgacgtt tttcccagtt
    22381 caggaaaata tccaccgcaa caatatcctg tctaagacca tcgtaccagc ccgcatttct
    22441 gaaagtctag tagacaaggc taaagctatg gcagtgcgaa tcgcagaaca actcaacttg
    22501 tctggaactc tctgtgtgga aatgtttgcg actgatgatg acgttattgt caatgaaatc
    22561 gccccacgac cacataactc tgggcactat tctattgaag cctgtgattt ctctcagttt
    22621 gacacccata ttctcggtgt tctcggagca ccattaccag tcatcaaact ccatgcgcct
    22681 gccgtcatgc ttaacgttct cggccagcat gttgaggccg ctgaaaaata tgtcacagaa
    22741 aattcaagcg cccacctcca catgtatggt aaaatagaag cgaagcacaa ccgcaagatg
    22801 ggacatgtga ctttgattag taatgaacca gatagtgtgg gagagtttta ggggagaggg
    22861 gtctaaagaa aaaatgtttg aaaaaattaa aggaattaat ataaaatcag gtatttttga
    22921 agatgaaaca aaattagaac tctttgaagg aaattttgag ggaacaaatc cagtacaaaa
    22981 cgatagggca agtttattgt ttggaaggaa tggttcaggg aaaagtacca ttgctcgagg
    23041 aataaatcaa ttaaaaaatg gtgagattgg aacagataga gtatcattta ttgataaaaa
    23101 taataataat attgtactta gtgatactga acgaaaatcg atatttgttt tcaatgaaca
    23161 ctatgttgat cagaaagtca aaattgctca agaagggtta gatacaattg taattttagg
    23221 tgaacaggtt gatatcgatg aggaactgga tagattaaga acgcagttat cagaatcaca
    23281 aattgaatct caagattatt atgctgaata tgaagaatat ttagatgaaa aaaatgaaaa
    23341 atctccagat ttttggaaaa aggaaatgac agattctttg aaaggagtag gcaactgggc
    23401 cgaaagagat agggagataa aaggaaatcg agctgcatct cccgttcata ataatacctt
    23461 tcaaaatttt gttgatttac aaccaatctt agataaaaat gagttagagg ttgaattcaa
    23521 caataaaaaa gctagatatt tttcaataag agattccgca gttactataa ataatgaact
    23581 atctttacct gatattaatt ttgatagcaa tgaattatca actttattgt ctgaaaaaat
    23641 cgaagaacct gagttgaatt ctagggataa gtatttactg acattattat ctgattccac
    23701 aaaaggtgaa cgtcatttga gagaagttaa agatttcttt gaagatgaac atcaaaaaaa
    23761 atgtcctttc tgtactcaat cagtatcaga agatgttaaa gttgaactca cgaatggcat
    23821 aactaaacta ctatcaagag cagtcgaaga acaccaatcc gcattgagag gtaaaaaaat
    23881 tgatgagatt aatcaagatt tttctggtta tgaacagata gatccaatat taattcagtc
    23941 ttatcaaaat agtattaatg ctttgaatgc taaatttaac gaaattaact caataatcga
    24001 taagaagatt gataatccat ataatatagt tgagttacct aatataagct tttctcaaga
    24061 attaagtcaa gcagagcatg atattgaaaa aattaaccaa gcaattatca aacataattc
    24121 agaaatctcg ggtattcaaa agttaaaagt agatctcctt caaataaata atgaattagc
    24181 tttttatgaa attcaagatg catacaaaaa gtttcaagag aaaacaaata aaaaagcaat
    24241 ttgtgaaaat aattataata acagtagtaa acgagtaaag gattatgaga agcagatttc
    24301 tgatttagaa gacaagaaac ttaatataga tattgcagtt gatgaaatta ataaaagttt
    24361 aaattacata tttttttcaa aaaatcggtt agctatacag aatcaaaacg gaaaatacta
    24421 tctgttatca agaggtaagt ctgtggtccc cagtagggtt tccgtagggg aacgaaatgc
    24481 gctggcatta tgttatttct ttactgagat aattcaacag agagagttag cagatgctta
    24541 tagtcatgaa tattttattg ttattgacga tccaatttct agttttgata tggaaaataa
    24601 agttggaata acctcgtatt taaaatattg tttaactaga ttttttaagg ggaatagtaa
    24661 tactagagtt ttactaatga cccatgataa acaaacaata tatgactttg atatcttttt
    24721 gaaagagata atggaatcct gtaaagaaga ggaaggtgga caaaaatcta aatacaagaa
    24781 gttagaattg gtttctggta aattacaaga attcaaaact agtactcacg attatacaga
    24841 actacttgaa atagtcttcg gttatgcatt gggaaatagt acacctactt cggaaagttt
    24901 tgttgggaat gcaatgagaa aaattttaga agcctatggt agttttaatt ataagaaggg
    24961 aattgccgag ctaacaacag atcctttaat tgttgaaaaa attgataaag aatacagaac
    25021 ttattttgag aatcttatgt atagactggt tttaaacggt gaaagtcatt ttaaggatcc
    25081 ggttaaaact ttgagtattg atttctttga taccatttct gatgaagaac gaaaaaaaac
    25141 agctagagat ttactagttt tgctttatct tttagatgat ttacatgttt taaaacattt
    25201 agagggtgta tcaaatgcgg aaaatagact tgaacaatgg aagtgtgaga ttttagaata
    25261 agagaatcat accatttgac ttattgcaat ggttgaagtt tgcatgatag ctgattagag
    25321 taatcaaagg attattactt cctaatttta ttttctacaa accctaattt agcatctaat
    25381 aatgcaaagt ttcctgagcc tcatagataa aaaagatttt taaggagaaa aacatgatca
    25441 accgttactc tcgccctgag atggcgaata tttggagtga agaaaataaa taccgtgctt
    25501 ggcttgaggt ggaaatcctc tctgacgagg catgggctga gttgggggaa atccctaagg
    25561 aagatgtggc tttgattcgc aagaaggcgg actttgacat cgaccgtatt ttggaaattg
    25621 agcaggagac gcgccacgat gtggtggctt tcacgcgtgc ggtttctgag actcttggtg
    25681 aagagcgcaa gtgggttcac tatgggttaa cttctaccga cgtggtggat actgcctatg
    25741 gttacctcta caagcaggcc aacgacatca tccgtcgtga ccttgaaaac ttcactaata
    25801 tcatcgctga caaggccaag gagcacaagt tcaccatcat gatggggcgt actcatggtg
    25861 tgcacgctga gccgacaact tttggtctta aattggcaac ttggtatagc gaaatgaaac
    25921 gcaatatcga gcgcttcgag catgcggctg ctggtgtaga agctggtaag atttctggtg
    25981 cggttgggaa ctttgccaat atcccaccat ttgtagagga gtatgtctgc gataaacttg
    26041 gcatccgtgc ccaagaaatc tctacacaag tccttcctcg tgaccttcac gctgagtact
    26101 ttgcggttct tgccagcatt gcgacttcaa tcgaacgtat ggcgactgag attcgtggtc
    26161 tacaaaaatc tgagcaacgc gaagtagaag agttctttgc taaagggcaa aaagggtctt
    26221 cagcaatgcc tcacaaacgc aacccaatcg gttctgaaaa tatgactggt ctggcgcgtg
    26281 tcattcgtgg tcacatgatt acggcttatg aaaacgtcgc tctctggcac gaacgcgata
    26341 tttctcactc atcagctgag cgtatcatca caccagatac gaccattttg attgactaca
    26401 tgctcaaccg ttttggaaat atcgtcaaga acttgacagt cttcccagaa aatatgatcc
    26461 gaaacatgaa ctcgactttt ggtcttatct ttagccaacg ggctatgttg acattgattg
    26521 aaaaaggcat gacccgtgag caagcctatg acttggtgca accaaaaaca gcctactctt
    26581 gggacaacca agtagacttt aaaccacttc ttgaggcaga ttcagaagta acatcacgtc
    26641 tcacacaaga agaaatcaat gaaatcttca acccaattta ttacaccaaa cgagtggatg
    26701 atatctttga acgtcttgga ctaggtgatt aattaaaaaa taaacagcga gcttcaatct
    26761 cgctgtttat tttttatcga aaagacttag tcttcttttc ttttagtgag tccataggct
    26821 gctagtgtgg acatgagtcc tgcgactact agtcctgcag aatcgtgagt tcctgtttca
    26881 ggaagttttt tctctgttac cacaggagct ggatcttgag gaagagcttt gctttcctca
    26941 gcaggagcag ttgatggagc tggttggctt gggatttcta gtcttggttt ttcttcagca
    27001 atagcggctt gtccgttttc atcgcctaca tgtgttacca tagttccgac ttcgactatt
    27061 tgagtaacgg cttcctgtgc tacgacacta tttacaagtg ttttcacttc cttaccatcg
    27121 gcagaagtgc tcacagagta gaagttgcta cgatgtccat tgacgccctt agtaatgact
    27181 tgtgtttttc ctttgagtaa gagtggattt tcacgagtca ctgtggtaaa tggaatttct
    27241 tctttttgga tatccagtct aggttttacc tcagtagttg gtgcaagacc actttcatca
    27301 cccttgtgag ttacaggagc gccaacttca accacttggt ttataacttc tttggttacc
    27361 tggctatcaa ggactgtttc tgttgttttt ccattttcag tgagtacaga gatgtaatga
    27421 gttcgttcac ctttgactcc tgctgtgata atattttcct gaccagctgg gaggttagga
    27481 ttttctttct tgataacttc aaatggaatt tcttcagttc ttgtgatgag ttctggtctg
    27541 gtttcaacat tggcagccac ttcattttca tccaggcttc ctgaatgagt tgcagctggt
    27601 ttgaggcctt gaagagcggc ttttaggttg gctacaagtg tgtcaagctc agcttgttta
    27661 ttacggttga ggttgtaatt tagagctgtt ttagctgcgt caagggcctc aagactttct
    27721 ttactatatc cttctaagtt tgtaggaatt ttagctaatt cttcgcggag agcattataa
    27781 ttagcacgga agtagtcttt gttgtggtct gcaaaggcag tcatgagttc aaagatttcc
    27841 tcttccttgt actcagcgct tggtctatct gcccagattg aaagcatact tccgactgtt
    27901 ggaagatcta cttcaggata tttggtagaa gctagttgat tgaatggaac tttaccagaa
    27961 ttttcaactg cttttgaaag agggtaagct tcatcttgtt tgtgattgcc tataacataa
    28021 taccagtcac cgttggtatt caagaattta tagcctttgc ttgctaggta ttgaggtgat
    28081 gcgaggttat atccccacca gcctttagac cagtaagaaa tcaagacatc tttgtcaaac
    28141 tgaacatcgt ccttgtcttc atagtagaag ccatcgttga aggccattgg ttgaagccct
    28201 ctttctttgg ccatagctgc gagggtgttg gcatattcgg caaatttgcc atagagttga
    28261 taccacttga ggtagtacca gccttgggca ctagtcgcat cgttggcgta ttcgtcagta
    28321 ccaaagttga aaatctttgt tttacctgca aagaagtcca tgtatttacc gatgagggct
    28381 tttacaaagt tcatcgcttc ttcgtttttc aagtccatag ttgtttttga aactttatca
    28441 aagtgggctt gaggattttt aatacctaat ttttccatgg caaccagcat agcatccatg
    28501 tgacctggac tgttaatagc tgggatgaga ccaatgtcct tagatttagc gtattcaatt
    28561 agctctgtca cttctgcctg tgttagtgca gtaccgtttg gatcgtcgta gtaagcttta
    28621 gttccttcga taatagcttt tttaacgtca tcactagcat aggtttttcc gttggcagta
    28681 atggtcatat cattgagtag aaagcgaagt ccgtcatttc ctagaaggag atggacatca
    28741 gaatatccga gctcactggc cttgtctacg atgcgtttga gctggtccag agtaaagtat
    28801 ttgcgtccag catcgattga gattaccttg tttttggcaa gtttttcaac ctcacgttta
    28861 gcttcttctt ctttttgagc ttcaggcgtg agggtcaagt tgttgacagt ttcttgaagt
    28921 ttagcaatgg cttgatcaat cgtatcttgt tgggcacggc taaggttgct atcgagagag
    28981 cgaatagctt tttcagcttc ttttacggcc gtgacgcttt ctgcagtata acggttcagg
    29041 tcttttggta cctcgttaag tgcttgctct gcagattcat aatcagctgc gaagtattca
    29101 gcgttggcat ttgcaaaatg acgcatgagt ttgaagaggc gtgatggtga ataacgtgca
    29161 gatggagtgt cagcccaagc agctaccata ccaccgatga ttgggatatc agctccttct
    29221 gtttttggta cagaagtgat tggtgtgttt ttaataccat tgagcccctg atcgagattg
    29281 taccagcctt ggccatcagc gtttcgtcca agaacgtagt accaagcatc attggtatta
    29341 aggatttggt gacctttttc agctagtagt ttagaagaag cgacatcgta gcctccccaa
    29401 ccaccagtcc acatagaaac gatgatgtct ttgtcaaaac taccaaagct tgtgtcgcta
    29461 ttgtagtaga taccgtcgtt aaaggccatt ggtttgagac cgtgcgattt tacaatacga
    29521 gcgaggtcat tggcgtaggc aataaatttt tcatagcctt ttacagggta gccttcgttt
    29581 ggatagtatt tatcagcttg aagcacactc caacctttag catctgtcgc atcattggca
    29641 tattcatcaa gtccgatgtt gaagatttca gtctttttcg cgaaataagc agcatacttg
    29701 tcgataaggg cttttgtaaa agcgacagct tgttcgttgt caagatcgac agtacgggct
    29761 gatttcttcc caaaatagct aaagttaggg ttttggattc ccaattcttt catggcattg
    29821 agaatcgcat ccatgtgtcc aggactattt actgtcggaa tgagaccgat acctttatct
    29881 ttggcatagt taatcagatc tgtcatttga ctttctgtta agtgattgcc gtttggatcg
    29941 ttgtaataat catttgtacc tttttcaatg gcgcgtttga catcgtcact ggcataggtc
    30001 ttgccgttag ctgtgatgct catatcgtcc aacatgaaac ggagtccatc atttccgact
    30061 aataggtgta aatcagtgta gccataatgt ttcgctttat cgatgatttc cttgagctgt
    30121 tctggtgaga aatatttacg tccagcatca atagaaacaa ttttcttttt cgctagtttt
    30181 tcatttacag ttgcagcacg ttcctttcct gtctctgttt ccggtttgtc agcctctgct
    30241 ttcgcttcat cttttttagc tggtttatcc ttgtcagtct tgtctgtatt tgactcttta
    30301 gaatcaacct ctttcgcttc ttccttttta gggctagctt cttcttcctt tttattagca
    30361 gtttcttttt cagcagaagt tggagttacc acctctgctt tatcactagg agttgaacta
    30421 acttcctctt gtggtttttc ttctgttttt ggaagactag ctaccttatc agtagctgga
    30481 gtttctgttt ctacagtttt tggagcttct ggttgaagct ctgctttagg tgtttcctca
    30541 gtccgatttt cggatgattg aggggaatca gaaaccgtat ggatggtcgg ttggttttct
    30601 gtagtagtag gagtaactcc atcggctgca acagtctgtg cttggaaggc aaatccaatt
    30661 agaacagaag ctgctcctac agcgtattta cgaatagaaa aacgctgttg tttttcatgt
    30721 ttcattgcaa aacctcctga ttgcattgtt atattgatag cgattatata aatcaacgcc
    30781 tttattttat ttcttatatt aacgagagtc aagaggagat gacaaaaaac tataataagt
    30841 ataaaaaaat ataaaattta aacttaagat ttcagattgg tcgaaaaaat acatatatat
    30901 atctagtata atttttggtt ctatttctat aaaatattcc acaaattata gaatcttcca
    30961 aaaataggta agcgctacct ttttggtgtg gtataataag catagaaaaa gcccgagcga
    31021 ttaggctcag gctttcttct tagtgatcac ggtcacatga gatgaattta atcttgtagt
    31081 aatcagatcg tttgtaagtt tcactgtatt ctaaaacttg gccagttgat tcgagtttgg
    31141 tgattttagt ttgtaggaca gtagggaatt gttcatcgac tccgaggact gaagccgcat
    31201 gttctggagt tggaaagact atttcgttga tttcttcaaa gtgttcatca ttcatgtgaa
    31261 tgtggtagtc taacttgaaa cgattataga tagaactata gtattcaagg tttggataat
    31321 ttgcgttgat atattgttct gggatgtagg atgtatggta gatataaacg acaccgtttg
    31381 attcgcggat acgttcaatc ttgtagtaga attgatcgcc gcgtagaccc aatttttcca
    31441 agtaaacaag cttgtttccg cgttcaattg aaagaacagt taccttatca tctttagcat
    31501 tgaagagttc aatatctgaa aactctacaa gcttgtgttt gcgtgcacgt gaaacgaagg
    31561 ttccttttcc ttgttggcgg acaatatagc catctttggc aaggtcgttt aaggcgcgaa
    31621 caactgtgat agagctgaca tcgtacattg aaatgagttc tgcttcagtg taaaatttat
    31681 ctccactgct aaactgccca gagatgattt tattttttaa ttcgtctttt atgtattgat
    31741 atttgggaat tgccatattt ttacctctat tttccttctc catagaaaat tttaccataa
    31801 aagcgaaaaa aatagtagtc ttttgaataa aaaattagaa taatagtttg aaaaattaag
    31861 cgatataggg attgctcata ttttatcaat gcattctata caaaattatt ttaggtccta
    31921 tattccgaat ttaaagagcg tttgaaatgg gtctaaaaat gtttgaaact aattgaatgt
    31981 gtgtataata gtaaaaatgc agtaaatatc ccgacaattt ctattgacaa ttcaaacaga
    32041 ttggtttata attaatataa caacaaatga aagcgcaaac tttcgcggtc ggaaggtagt
    32101 tttatgacac gatttgagat acgagatgat ttctatctcg atggaaaatc atttaagatt
    32161 ttatctggtg ccattcatta ttttaggatt cctccagagg attggtatca ttcgctctat
    32221 aacttgaagg ctcttggttt taatacggta gagacttatg ttgcttggaa tttacacgag
    32281 cctcgtgaag gtgagtttca ttttgaaggt gatctggatt tagagaaatt tctccaaata
    32341 gcgcaggatt tgggtctcta cgcaattgtg cgtccgtctc catttatctg tgcggaatgg
    32401 gaattcggtg gcttaccagc ttggctcttg accaagaaca tgcgaattcg ctcatccgac
    32461 ccagcatata tcgaggcagt tggtcgctac tatgatcagt tattgccaag actggtgcct
    32521 cgtttgttga acaatggtgg caatattctc atgatgcagg ttgaaaatga gtatggttct
    32581 tacggagaag ataaggctta cctgagagcg attcgacagc taatggaaga gtgtggcgta
    32641 acctgtcccc tctttacatc agatggtcca tggcgagcta ctctgaaagc tggaacctta
    32701 attgaagagg acctctttgt aacaggaaac tttggttcta aggcacctta caacttttcg
    32761 cagatgcagg aattctttga tgaacatggt aagaaatggc cactcatgtg tatggagttc
    32821 tgggatggtt ggttcaatcg ctggaaagaa ccgattatca cacgggatcc taaggaattg
    32881 gcagatgcag ttcgagaggt tttggaacaa ggctctatca atctttacat gttccacggt
    32941 ggtacaaact ttggtttcat gaatggttgc tcagctcgag gaactttgga cctgccacaa
    33001 gttacatctt atgattacga tgcccttctg gatgaagaag gaaatccaac tgctaaatat
    33061 cttgcagtca agaagatgat ggcaacacat ttttcagagt atccgcagtt ggaaccactc
    33121 tacaaagaga gtatggagtt ggatgctatt ccactagttg aaaaagtttc tttgtttgaa
    33181 accttagata gcttgtcaag tcctgtagaa agtctctatc ctcaaaagat ggaggagctg
    33241 ggacaaagtt atggctacct actttatcga acagaaacaa actgggatgc agaagaagaa
    33301 agacttcgta tcattgatgg tcgagatagg gcccagctgt atgtcgatgg tcagtgggtt
    33361 aaaactcaat atcagacaga gattggggaa gatatttttt atcaaggtaa aaagaaaggg
    33421 ctatctaggt tagatatctt gatagaaaat atggggcgtg tcaactatgg gcataagttc
    33481 ttagcggata cgcaacgtaa gggaattcgg acaggggtct gtaaggatct gcatttctta
    33541 ctaaactgga aacactatcc actcccacta gacaatcctg agaaaattga tttttcaaaa
    33601 ggatggactc aaggacaacc agccttttac gcttatgact ttacagtcga agagccaaaa
    33661 gatacttacc tagacttgtc tgagtttggt aagggagttg cctttgtcaa tgggcagaat
    33721 ctaggacgtt tttggaacgt tggcccaact ctctcacttt atatccctca tagctatctc
    33781 aaggaaggtg ccaaccgtat cattatcttt gaaacagaag gtcaatataa agaagagatt
    33841 catttaactc gtaaacctac actaaaacat ataaaggggg aaaacttatg acaattgtag
    33901 gatgccgtat tgatggacgt ttgatccacg gacaagtagc caatctttgg gctggaaaac
    33961 taaatgtttc acgcattatg gttgtagacg acgaagttgt caacaacgat attgaaaaga
    34021 gtggtttgaa acttgcgaca ccaccaggtg tgaaattgag tattttgcca gttgagaaag
    34081 ctgcagccaa tattcttgct ggtaaatacg atagccaacg tctctttatc gtggctcgta
    34141 aaccagaccg cttccttggt ttggtagaag caggtgtacc acttgaaacc cttaatgttg
    34201 ggaatatgtc tcaaacacca gaaactcgtt ctattacacg ttctatcaac gtagtagaca
    34261 aggatgtgga agacttccac aaactggcag aaaaaggtgt taaacttact gctcagatgg
    34321 ttccaaatga tccaatttca gactttttga gcttattaaa ataggaaaaa aatttttagg
    34381 aggtcattgt tatgatacaa tggtggcaaa ttttacttct cactttgtac tcagcttatc
    34441 aaatctgtga tgagttgacg atcgtttcat ctgcaggttc ccctgtattt gctggtttca
    34501 ttactggttt aatcatggga gatgtgacta ctggtttact tatcggtggt aacttgcaac
    34561 tgttcgttct tggggttggt accttcggtg gtgcttctcg tatcgacgca acttctggtg
    34621 cggttcttgc gacagccttc tctgtttcac aaggaattga tgcaccgctt gccattacta
    34681 caatcgctgt accagtagca gctctcttga cttacttcga cgttcttggt cgtatgacta
    34741 ctaccttctt cgctcaccgt gtggatgctg caatcgaacg ctttgactat aaaggtattg
    34801 aacgcaacta cttgcttggt gcgattccgt gggctctatc tcgtgccctt ccagtcttct
    34861 ttgcccttgc ttttggtggt gcctttgtac aatcagtagt agacttcgtt gaagcctaca
    34921 aatgggttgc agatggcttg acacttgcag gacgtatgct tccaggtctt ggatttgcaa
    34981 tcttgcttcg ttaccttcca gttaaacgta accttcacta ccttgctatg ggatttggtt
    35041 tgacagctat gttgactgtt ctttactcat atgtaacagg tcttggtggc gctgttgctg
    35101 gtatcgtagg tactcttcct gctgaagttg ctgaaaaaat tggtttcgtg aacaacttca
    35161 aaggtttgtc tatgattggt atttctatcg taggtatttt ccttgcagtg cttcacttca
    35221 aaaatagcca aaaagtagct gtagcagcac cttctacacc atcagaaagt ggggaaatcg
    35281 aagatgacga attctaatta caaacttaca aaagaagatt ttaatcaaat caacaaacgt
    35341 agcttgttta ctttccaatt aggttggaac tacgaacgta tgcaagcttc tggttacctt
    35401 tacatgatct tgcctcagtt gcgtaaaatg tatggtgatg gaactcctga attgaaagaa
    35461 atgatgaaag ttcatactca attcttcaat acttcaccat tcttccatac cattatcgct
    35521 ggttttgacc ttgccatgga agaaaaagat ggtgtaggtt caaaagacgc tgttaacggt
    35581 atcaagacag gtttgatggg accattcgct cctcttgggg atacaatctt tggttcactt
    35641 gtacctgcta tcatggggtc agtcgcagca actatggcta tcgctggcca accttggggg
    35701 atcttccttt ggattgcagt tgcagtagcg tatgacatct tccgttggaa acagttggaa
    35761 tttgcttaca aagaaggggt taaccttatc aacaacatgc aaagtacctt gacagctttg
    35821 attgacgctg catctgtact tggtgtcttc atgatgggtg ctcttgtagc aacagtgatt
    35881 aactttgaaa tttcttacaa gttgccaatc ggtgaaaaga tgattgattt ccaagacatc
    35941 ttgaaccaaa tcttcccacg tttgcttcca gcaatcttta ctgcctttat cttctggttg
    36001 cttggtaaga aaggtatgaa ctctactaaa gctatcggta ttattatcgt acttgctttg
    36061 actctttctg cccttggtca ctttgcactt ggaatgtaat tccttatgac taaatcatta
    36121 attttggtga gccatggtcg cttctgtgag gagcttagag gtagcacaga aatgattatg
    36181 ggcccacaag acaacattta cacagtagct cttcttccag aagatggccc agaagaattt
    36241 actgctaaat ttgaagctgt tattggagga ttggatgatt tcctagtctt tgcggatctt
    36301 ctcggtggga caccttgtaa tgtggtgagt cgcttgatca tggaaggtcg tgatattgac
    36361 ctttacgcag ggatgaatct tccaatggtg attgaattta tcaatgcgag ccttacaggc
    36421 gcagatgcgg actacaagag ccgtgctgca gaaagcattg tgaaagttaa tgacctgtta
    36481 gcgggcttcg atgatgacga agatgaataa tactcttcga aaatctcttc aaactacgtc
    36541 aacgtcgcct tgccgtaggt atatgttact gacttcgtca gtcttatccg gcaacctcaa
    36601 aacggtgttt tgagctgact tcgtcagttc tatctgcaac ctcaaagtag tgctttgagc
    36661 agcctgcggc tagtttccta cagattttag ttggaactcg attcaattca tgtgacaacg
    36721 tgaaaatcgt tagagcattt tatatagaat atacatggga atggagctta ctcccattcc
    36781 catatttaat agaaaaagag gaactcaatg ctacattata caaaagaaga cttgctcgaa
    36841 ttgggtgcag aaatcactac gcgtgaaatc taccaacaac ctgatgtatg gagagaagct
    36901 tttgaatttt atcaagcaaa acgtgaagaa attgcagcct tcctacaaga aatcgctgat
    36961 aaacatgact atattaaggt tatcttgaca ggtgctggga cttctgctta tgtgggagac
    37021 accttgctac cttactttaa ggaagtctat gacgaacgca aatggaattt caatgctatt
    37081 gcgacaacag atatcgttgc caatccagca acctatttga aaaaagatgt ggcaactgtc
    37141 cttgtgtctt ttgctcgtag tgggaactcg cctgaaagtg tggcgactgt tgatttggcc
    37201 aaatccttgg tggatgagct ttatcaagtg acgattactt gtgcagcaga tggtaaattg
    37261 gctcttcaag ctcacggtga tgaccgtaat ctcttgctct tgcaaccagc tgtctctaat
    37321 gatgctggat ttgccatgac ttctagcttt acgtctatga tgttgacagc tctcttggtc
    37381 tttgatccta cagaatttgc tgttaagtct gaacgttttg aagttgtatc tagtcttgcc
    37441 cgtaaagttt tagacaaggc agaagatgtc aaaaagctcg ttgatttaga ctttaaccgt
    37501 gtcatctatc taggcgctgg tcctttcttt ggacttgctc atgaagctca gctcaagatt
    37561 ttggaattaa ctgctggtca agttgcgacc atgtatgaaa gcccagttgg cttccgtcac
    37621 ggtccaaaat ctcttatcaa cgacaataca gttgttttgg tctttggtac aacgacagac
    37681 tacactcgta agtacgactt ggacttggtt cgtgaagttg ctggtgacca gattgctcgt
    37741 cgtgttgtgc ttttgagtga tcaagctttt ggtcttgaaa atgtcaaaga agtggccctt
    37801 gattgtggcg gtgtcttgaa tgatatttac cgtgtcttcc cttacatcgt ttatgcccaa
    37861 ctctttgccc tattgacttc actcaaggta gaaaataaac cagatacacc gtctcctaca
    37921 ggtacagtaa accgtgtagt acaaggtgtc ataattcacg aatatcaaaa gtaagacagt
    37981 gtttatgaat tcttgacaag aggatttgta aattatcaga taaaccatag attgtcagta
    38041 cgctttctat ggtttgtttg cttgagagaa atagtaaaag gagaacagaa tgaaagcata
    38101 cacagagcgt gtatttggaa atgttgaggg cgaggatgtc ttggcctatc gatttgagac
    38161 agacggtggc taccaacttg aggttatgac ttatggcgcg accatcttgc gctatgtcgc
    38221 acctgacaag gctggaaatt ttgccaatgt tatcttggga tttgatgact ttgatagtta
    38281 tgtaggcaat agtcccaagc atggagcaag tgtaggtcct gtagcgggtc gtattgcagg
    38341 tgcgaccttt gagctcaatg gtaagaccta tgaccttgag gttaataatg ctagcaactg
    38401 taatcacagt ggttcaactg gttgggattc cagcttgttt gaagttgaag aagtaagcga
    38461 tcatggcttg actctctaca cagagcgtac agatgggaca ggagggttcc ctggaaatct
    38521 caagatttgg atcagttatc acttggaaga aactggtgcc tatgaaatca gctacaaggt
    38581 aacgaccgat caggatacgc tggtcaatcc aaccaaccac agctatttca acttgtctgg
    38641 tgatttcacg cagacgattg accgtcatgt cttccaacta aacacagagg gcatttactc
    38701 aatcgctcct gacggtgttc ctgccaaaac tccagaagcc aaccgtgatg tggtcaaaca
    38761 catctacaat ggtgccttgt tgaaggatat ctttgcagaa gaagatgagc aaatccagct
    38821 ggcatcaggt ttggatcatc catttgccct tcctgcaggc catgacaatg ctggattcct
    38881 ttatgaccaa aattcaggtc gcttcctgct tttcaagaca gaagctcctt gctttgtggt
    38941 ctacacagca aactttgtgg atgaaagtgt catcatagga ggtcagccaa tgctacagca
    39001 caatgggatt gctcttgaag cgcaagcttt accagatgcc attcacagtg accttaaagg
    39061 ccaagtcatt cttaaagctg gtcaaacctt caccagtaag acacgttatg aacttgttgt
    39121 gaaataaaaa agctggtcaa aaagtcttta aaattaaaat aacgcatatt gtcaggtgat
    39181 gaaaagtttg ataatatgcg ttttattatg aaatgattta ctttatatta tcctgaaatg
    39241 gtgttatttt tgagttatct ggcttgactt tcttgatgga aattatataa tagttgcaac
    39301 aataataatt acaacgaaaa aagaggacca tttatgacct atgaatacaa gagtcacatt
    39361 tatttggcag agacagtttt aaatgtaaag gatttggcca gtcaaacagc cttttatcag
    39421 caagttatcg gtttagaaat cttatctcaa actgagacag agtccattct aggccttggt
    39481 ggaaaagtct tggtacagct gattcaagca caagagagcg gagaagtgag ggaacattat
    39541 ggtctttacc atttggccat tctcttgccc acacgcaagg ctttggctga tgtcttgaaa
    39601 cacctgacag atttacagat tcctcttgtc ggcggtgcag accatggtta cagtgaagct
    39661 atttacttgg aagatttgga gggaaatggc attgaactct atcgagataa gccagtttcc
    39721 acatgggata ttcgagaaga tggacgcatt atcggagtga cggaggctct tgcggcgcag
    39781 gacatttatg agttggggga aagagtagag ccctttatcc tggcagaagg tacgagaatg
    39841 gggcatattc atctttcagt caaggatagt cgaaagtcca gccagtttta tcaaaaggtg
    39901 ttagggctag aggataaatt cagtgtgcct agcgctagtt ggattgcggc tggagattac
    39961 catcatcatt tagcagttaa cgaatgggga ggaaaaggtc tggcttcgcg taagcaaggc
    40021 ttaccaggtt tagcctacta tgtcatcgaa gtcgcacata aaaaagaact gttaacgatt
    40081 gcccaacgag cacaagaagt tgacgcacca atcaaatgga tgacatcgag ccaattggaa
    40141 atcacagact cagatggcat cgtgacccgt attcgtttag caaggtaaaa ttaggaattt
    40201 ttaataagtt ataagtattg ctagtttgct ttttgaacgg tctttggtaa cagaactgcg
    40261 tgagctggat gggtgagaat tttgacaaag aagctgatta gagatataat gaagaaaagt
    40321 cgagcaagga aaaagaaatg acaaattcaa agtatattac ttgtttgaaa cgttcagagg
    40381 gccagttgtg tgggattcaa aagatgattg aaggagatcg tgactgtgct gatcttgtga
    40441 cgcaactgac agcagtgaga tctagtgtag agcgcgtgat tgagatgata attaccgaaa
    40501 atcttactga atgtatcaat cagccactag atgattctga agctcaaaag gaacgcttag
    40561 aaaaggctat ccgatacttg attaaacgga aataaatgaa tgttttgaga cgatatgtgc
    40621 aaaggtctat taactattag aatagtttaa tgtgagtcaa aagaagttgt aaaaaatctt
    40681 taaaattaaa aaaacgcata gtatcaggta ttgaaatgta ctgcccccaa aagttagatt
    40741 ttttctgtct aacttttggg gggcagtaca taaaaacctt gatagtatgc gttttattgt
    40801 ggggagattt atactcttcg aaaatctctt caaaccacgt cagcttcacc ttgccgtaga
    40861 tatggttact gacttcgtca gttctatcca caaccttaaa acagtgtttt gagcagcctg
    40921 cggctaactt cctagtttgc actttaattt tcattgagta ttacttcatc ttctcatgaa
    40981 attgagtttt tgcccagctc ctcttgatta ttctacttga ccgggctaag cattcatacc
    41041 accttctacg ttggtaacgg tgaggccttg ggagctgaga aattggcagg tagatgcaga
    41101 gcggactcct ccttgacaaa taacatagta ttcatggtca ggtttgagtt ctttgtagcc
    41161 ttgctctaag gtacttaatg gaagattttt ggcacctggt gcatgtcctg cttggaattc
    41221 atgtgcttca cggacatcga taagttctag attttcattt tgatattttc cataaaagtc
    41281 agccatgctg atactagttt ccatattcta ctccttctgg gttagccatt ttgtatagtg
    41341 aataagcgcc gtcaaggttt tggacggtaa atcctgcttg cttgaggata ggctctgcga
    41401 tatagctgcg caaactactg tggcaactga cgatgtaggc ttgtttttct cctcagttca
    41461 tcagcttcct ccttgacact cggtcagatt ttgatacaat agtacaaaat tagaggaggt
    41521 gggctatgat tcagaaacat gcgattccca ttttagagtt tgatgataat cctcaggcgg
    41581 ttatcatgcc caatcacgag gggttggatt tgcagttgcc aaagaagtgt gtctatgctt
    41641 ttttaggtga ggagattgac cgctatgcga gggaagtagg ggcgaactgt gttggcgaat
    41701 tcgtttctgc taccaagacc tatccagtct atgtcatcaa ctacaagggt gaggaggtct
    41761 gtctggctca ggctcctgtt ggctccgctc cagcagccca gtttatggat tggttgattg
    41821 gctatggtgt ggagcagatt atctctactg ggacctgtgg tgtcctagct gatatagagg
    41881 aaaatgcctt tctagtccct gttcgcgctt tgcgagatga gggagccagt taccactatg
    41941 tggcaccttg tcgttatatg gaaatgcagc cagaggctat tgctgctatt gaggaagttt
    42001 tggaagacag agggattcct tatgaagaag tcatgacctg gacgacagac ggtttttacc
    42061 gagaaacggc tgaaaaggtg gcttatcgta aggaagaagg ctgtgctgtt gtggagatgg
    42121 agtgttctgc tcttgctgca gtagctcaat tgcgtggggt tctctggggt gaattgttgt
    42181 tcacagcaga ttctctagcg gacttggacc agtacgacag tcgtgactgg ggctcggaag
    42241 cttttaataa ggcgctagaa ctgagtttag caagtgttca ccacctttag ttgtactggc
    42301 aaaggatttg ttttatcata aaatgtctag ctcatacttt tcaaaaatat gtttaaacga
    42361 ggtcaccttc ctcttgtcct aggcatgttg aggttgggaa aaatctttaa aatcagaaaa
    42421 acgtatcata tcaggtgatg aaaattttga tactatgcgt tttatgttgg taagatttag
    42481 agtgagatga aatgatactc ttcgaaaatc tcttcaaacc aggtcagctt caccttgccg
    42541 tatagatgtt actgacttcg tcagttctat ctgcaacctc aaaacagtgt tttgagcaac
    42601 ctgtgactag ctttctaatc gatgccttgg ttttcattgc ctataatcaa aaagagaaat
    42661 tttctcctga aaagcatata gagtagctgg cgttaaaagc tcctgtcttg cttttttgac
    42721 ctatagtcat atctatcaag tattgttctt gcctaagcta tcaataaaaa ggtggcattt
    42781 tttaggcttg gtgttagtga attttgcctt atcctatcta agtcatttcg agctttttat
    42841 ggtacaatgg aaacatgtta ttcaaattat ctaaggaaaa aatagagcta ggcttatctc
    42901 gtttatcgcc agcccgtcgt atttttttga gttttgcctt ggtcatttta ctaggctctc
    42961 ttcttttgag cttgcccttt gtccaagttg aaagctcacg agcgacttat tttgatcatc
    43021 ttttcactgc tgtctctgca gtctgtgtga caggtctctc aacccttcca gtagctcaca
    43081 cctataatat ctggggccaa ataatctgtt tgctcttgat tcagatcggt ggtctagggc
    43141 tcatgacctt tattggggtt ttctatatcc agagcaagca aaagcttagt cttcgtagcc
    43201 gtgcaactat tcaggatagt tttagttatg gagaaactcg atctttgaga aagtttgtct
    43261 attctatttt tctcacgacc tttttggttg agagcttggg agctattttg cttagttttc
    43321 gccttattcc tcaacttggc tggggacgtg gtctttttag ttccattttt ctagcgatct
    43381 cagccttctg taatgccggt tttgataatt tagggagcac cagtttattt gcttttcaga
    43441 ccgatttact ggtcaatctg gtgattgcag gcttgattat tacaggcggc cttggtttta
    43501 tggtctggtt tgatttggct ggtcatgtag gaagaaagaa aaaaggacgt ctgcactttc
    43561 atacgaagct tgtattatta ttgactatag gtttgttgtt atttggaacg gcaactactc
    43621 tctttcttga gtggaacaat gctggaacga ttggcaatct ccctgttgcc gataaggttt
    43681 tagttagctt ttttcaaaca gtgacgatgc gaacagctgg cttttctacg atagattata
    43741 ctcaggctca tcctgtgact cttttgattt atatcttaca gatgtttcta ggtggggcac
    43801 ctggaggaac agctggggga ctcaagatta cgacattttt tgtcctcttg gtctttgcac
    43861 gaagtgagct tctaggcttg cctcatgcca atgttgcgag acgaacgatc gcgccgcgaa
    43921 cggttcaaaa atcctttagt gtctttatta tctttttgat gagcttcttg ataggattga
    43981 ttctgctagg gataacagcc aaaggcaatc ctccctttat ccacctcata tttgaaacca
    44041 tttcagctct tagtacagtt ggtgtaacgg caaatctgac tcctgacctt gggaaattgg
    44101 ctctcagtgt tatcatgcca cttatgttta tgggacgaat tggtcccttg accttgtttg
    44161 ttagcttggc agattaccat ccagaaaaga aagatatgat tcactatatg aaagcagata
    44221 ttagtattgg ttaagaaagg aaagagcatg tcagatcgta cgattggaat tttgggcttg
    44281 ggaatttttg ggagcagtgt cctagctgcc ctagccaagc aggatatgaa tattatcgct
    44341 attgatgacc acgcagagcg catcaatcag tttgagccag ttttggcgcg tggagtgatt
    44401 ggtgacatca cagatgaaga attattgaga tcagcaggga ttgatacctg cgataccgtt
    44461 gtagtcgcga caggtgaaaa tctggagtcg agtgtgcttg cggttatgca ctgtaagagt
    44521 ttgggggtac cgactgttat tgctaaggtc aaaagtcaga ccgctaagaa agtgctagaa
    44581 aagattggag ctgactcggt tatctcgcca gagtatgaaa tggggcagtc tctagcacag
    44641 accattcttt tccataatag tgttgatgtc tttcagttgg ataaaaatgt gtctatcgtg
    44701 gagatgaaaa ttcctcagtc ttgggcaggt caaagtctga gtaaattaga cctccgtggc
    44761 aaatacaatc tgaatatttt gggtttccga gagcaggaaa attccccatt ggatgttgaa
    44821 tttggaccag atgacctctt gaaagcagat acctatattt tggcagtcat caacaaccag
    44881 tatttggata ccctagtagc attgaattcg taaagaggga tgacccctct tttttgatgc
    44941 ttaagatggc aaatagagac agaagcccct tgtcttctag taaaagttct tcaaaggctg
    45001 gactttatgg taaaatagaa ggaagtgaca agagagagta atactcaatg aaaatcaaag
    45061 atcaaactag gaaactagct gcgggctgct caaaacactg ttttgaggtt gtggatagaa
    45121 ctgacgaagt cag
//
LOCUS       DBERCW010000014        42840 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.014, whole genome shotgun sequence.
ACCESSION   DBERCW010000014 DBERCW010000000
VERSION     DBERCW010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42840
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.014"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(19..1977)
                     /gene="ftsH"
                     /locus_tag="ACL72M_000948"
     CDS             complement(19..1977)
                     /gene="ftsH"
                     /locus_tag="ACL72M_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGS0716101.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAHHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1993..2535)
                     /gene="hpt"
                     /locus_tag="ACL72M_000949"
     CDS             complement(1993..2535)
                     /gene="hpt"
                     /locus_tag="ACL72M_000949"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGS0716102.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2539..3816)
                     /gene="tilS"
                     /locus_tag="ACL72M_000950"
     CDS             complement(2539..3816)
                     /gene="tilS"
                     /locus_tag="ACL72M_000950"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGS0716103.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3813..5081)
                     /locus_tag="ACL72M_000951"
     CDS             complement(3813..5081)
                     /locus_tag="ACL72M_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGS0716104.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5074..5196)
                     /locus_tag="ACL72M_000952"
     CDS             complement(5074..5196)
                     /locus_tag="ACL72M_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGS0716105.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            complement(5201..5569)
                     /locus_tag="ACL72M_000953"
     CDS             complement(5201..5569)
                     /locus_tag="ACL72M_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGS0716106.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5562..5828)
                     /locus_tag="ACL72M_000954"
     CDS             complement(5562..5828)
                     /locus_tag="ACL72M_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGS0716107.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5886..9395)
                     /gene="mfd"
                     /locus_tag="ACL72M_000955"
     CDS             complement(5886..9395)
                     /gene="mfd"
                     /locus_tag="ACL72M_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGS0716108.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9396..9965)
                     /gene="pth"
                     /locus_tag="ACL72M_000956"
     CDS             complement(9396..9965)
                     /gene="pth"
                     /locus_tag="ACL72M_000956"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGS0716109.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSIDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10037..11152)
                     /gene="ychF"
                     /locus_tag="ACL72M_000957"
     CDS             complement(10037..11152)
                     /gene="ychF"
                     /locus_tag="ACL72M_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGS0716110.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11236..11430)
                     /locus_tag="ACL72M_000958"
     CDS             complement(11236..11430)
                     /locus_tag="ACL72M_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGS0716111.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEVTRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11495..12631)
                     /gene="dnaN"
                     /locus_tag="ACL72M_000959"
     CDS             complement(11495..12631)
                     /gene="dnaN"
                     /locus_tag="ACL72M_000959"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGS0716112.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12790..14151)
                     /gene="dnaA"
                     /locus_tag="ACL72M_000960"
     CDS             complement(12790..14151)
                     /gene="dnaA"
                     /locus_tag="ACL72M_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGS0716113.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14364..15122)
                     /locus_tag="ACL72M_000961"
     CDS             complement(14364..15122)
                     /locus_tag="ACL72M_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGS0716114.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15180..16361)
                     /locus_tag="ACL72M_000962"
     CDS             complement(15180..16361)
                     /locus_tag="ACL72M_000962"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGS0716115.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16544..17023
                     /gene="rlmH"
                     /locus_tag="ACL72M_000963"
     CDS             16544..17023
                     /gene="rlmH"
                     /locus_tag="ACL72M_000963"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGS0716116.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17067..17140
                     /locus_tag="ACL72M_000964"
     tRNA            17067..17140
                     /locus_tag="ACL72M_000964"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17101..17103,aa:Arg,seq:tct)
     gene            17305..17430
                     /gene="comC"
                     /locus_tag="ACL72M_000965"
     CDS             17305..17430
                     /gene="comC"
                     /locus_tag="ACL72M_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGS0716117.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIKGGEMRISRIILDFLFLRKK"
     gene            17451..18776
                     /gene="comD"
                     /locus_tag="ACL72M_000966"
     CDS             17451..18776
                     /gene="comD"
                     /locus_tag="ACL72M_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGS0716118.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYIFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     FKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18773..19525
                     /gene="comE"
                     /locus_tag="ACL72M_000967"
     CDS             18773..19525
                     /gene="comE"
                     /locus_tag="ACL72M_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGS0716119.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19577..19648
                     /locus_tag="ACL72M_000968"
     tRNA            19577..19648
                     /locus_tag="ACL72M_000968"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19610..19612,aa:Glu,seq:ttc)
     gene            19654..19727
                     /locus_tag="ACL72M_000969"
     tRNA            19654..19727
                     /locus_tag="ACL72M_000969"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19688..19690,aa:Asn,seq:gtt)
     gene            complement(19768..20310)
                     /locus_tag="ACL72M_000970"
     CDS             complement(19768..20310)
                     /locus_tag="ACL72M_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS0716120.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDVIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20489..22092
                     /locus_tag="ACL72M_000971"
                     /pseudo
     CDS             20489..22092
                     /locus_tag="ACL72M_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(22122..24674)
                     /locus_tag="ACL72M_000972"
     CDS             complement(22122..24674)
                     /locus_tag="ACL72M_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGS0716121.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24736..26358)
                     /locus_tag="ACL72M_000973"
     CDS             complement(24736..26358)
                     /locus_tag="ACL72M_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0716122.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26564..27589
                     /gene="trpS"
                     /locus_tag="ACL72M_000974"
     CDS             26564..27589
                     /gene="trpS"
                     /locus_tag="ACL72M_000974"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGS0716123.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27741..29219
                     /gene="guaB"
                     /locus_tag="ACL72M_000975"
     CDS             27741..29219
                     /gene="guaB"
                     /locus_tag="ACL72M_000975"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGS0716124.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29270..30367)
                     /gene="recF"
                     /locus_tag="ACL72M_000976"
     CDS             complement(29270..30367)
                     /gene="recF"
                     /locus_tag="ACL72M_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGS0716125.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30370..30738)
                     /gene="yaaA"
                     /locus_tag="ACL72M_000977"
     CDS             complement(30370..30738)
                     /gene="yaaA"
                     /locus_tag="ACL72M_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGS0716126.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30897..32147
                     /locus_tag="ACL72M_000978"
     CDS             30897..32147
                     /locus_tag="ACL72M_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS0716127.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYCSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32144..33427
                     /locus_tag="ACL72M_000979"
     CDS             32144..33427
                     /locus_tag="ACL72M_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS0716128.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33469..34290
                     /gene="rodZ"
                     /locus_tag="ACL72M_000980"
     CDS             33469..34290
                     /gene="rodZ"
                     /locus_tag="ACL72M_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGS0716129.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKISFLPLFYFIFFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34301..34846
                     /gene="pgsA"
                     /locus_tag="ACL72M_000981"
     CDS             34301..34846
                     /gene="pgsA"
                     /locus_tag="ACL72M_000981"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGS0716130.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34843..35670
                     /locus_tag="ACL72M_000982"
     CDS             34843..35670
                     /locus_tag="ACL72M_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGS0716131.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35655..36494
                     /locus_tag="ACL72M_000983"
     CDS             35655..36494
                     /locus_tag="ACL72M_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGS0716132.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36487..37281
                     /locus_tag="ACL72M_000984"
     CDS             36487..37281
                     /locus_tag="ACL72M_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0716133.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37340..38158
                     /gene="mreC"
                     /locus_tag="ACL72M_000985"
     CDS             37340..38158
                     /gene="mreC"
                     /locus_tag="ACL72M_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGS0716134.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38158..38652
                     /gene="mreD"
                     /locus_tag="ACL72M_000986"
     CDS             38158..38652
                     /gene="mreD"
                     /locus_tag="ACL72M_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGS0716135.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38746..39924
                     /gene="pcsB"
                     /locus_tag="ACL72M_000987"
     CDS             38746..39924
                     /gene="pcsB"
                     /locus_tag="ACL72M_000987"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGS0716136.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40148..40927
                     /gene="rpsB"
                     /locus_tag="ACL72M_000988"
     CDS             40148..40927
                     /gene="rpsB"
                     /locus_tag="ACL72M_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGS0716137.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41006..42046
                     /gene="tsf"
                     /locus_tag="ACL72M_000989"
     CDS             41006..42046
                     /gene="tsf"
                     /locus_tag="ACL72M_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGS0716138.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42361..42615
                     /gene="tnpB"
                     /locus_tag="ACL72M_000990"
     CDS             42361..42615
                     /gene="tnpB"
                     /locus_tag="ACL72M_000990"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0716139.1"
                     /translation="MDSLAYVVKTHFELDSFSGQVFLFCGERKDRFKALYWDGQGFWL
                     LYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFSITPKI"
BASE COUNT        13411 a         7395 c         7896 g        14138 t
ORIGIN      
        1 ctccagcctc tctcagggtt atttttcgtc attcattttt gactttactt catcatagga
       61 tagtgcatga gattcctctt ctactgcttc aggcatcttt cctgtttcgt aaagagcttt
      121 aatttgtgta ctatccaatg tttcgtattt caataatgct tctgcaatta acttgtgagt
      181 ttcacgattt gactgaataa tttcagcagc tttatttcgt gcctcattta ataatgaacg
      241 aacctcttca tcaatttcat aagctgtttg ttctgaaatt gatttttgag gactctgtgc
      301 accaagcata gcatggtttc cttcatattg tactgggcca agtttttcac tcataccgta
      361 ctctgtaacc attgcacgtg ccatttgtgt cgcttgttca aagtcgtttg aagctcctgt
      421 agtttggaca ttaaagataa tttcttcagc tacacgtcca cccattaagc cagccaattg
      481 ctctttcata tcttctttag atagaagcat ttgatcctct ttaggaagtg caatcatgta
      541 tccgcctgca cggccgcgtg gtacaattgt aaccttatgg acaacgcgag cattcgacaa
      601 gactagacca acaatggtat gtcctgcctc atggtgagca accaattctc gttctttttg
      661 tgaaactgtc ttatctttct tagaaggtcc agcaataact ctatcttctg cttcatcaat
      721 atctgaagca tcaattatcg atttattgcg acgagcagca actaaagctg cttcattcaa
      781 gacattctct aaatcagcac caacaaagcc tggagtttgt tgagccacta atttcaaatc
      841 aacatcttct gctaaaggct tgttcttagc gtgaactttc aagattgctt cacgaccttt
      901 aacatcagga cggccaacca atacttttct atcaaaacgt cctggacgca aaagggcagg
      961 atcaagtaca tctgaacggt ttgtcgcagc gatgacgata atcccttcat ttccctcaaa
     1021 accatccatc tcaatcaaaa gttggttcaa ggtttgttca cgttcgtcat tacctccgcc
     1081 gagaccgact ccacgttgac gtccaacagc atcaatttca tcgataaaga tgatagctgg
     1141 tgctgctttt ttggcatcct caaaaagaga gcgaacacga ctagctccaa ctccgacaaa
     1201 catttctaca aagtcagaac ctgagatact aaagaatgga acacctgctt ctccagcgac
     1261 tgccttagca agcaaagtct tacctgtccc cggaggtccc tccaaaagaa cacctgctgg
     1321 aatacgggct ccaagttttg tgaatcgttt tggatctttt aagaactcaa caacttcaac
     1381 tagttcttgt ttttcttcct cagctccagc aacatctgaa aatcttactt taatatcttc
     1441 tttatttgct gctttagcct tactacgtcc aaaactcatt ggattacggc cattgcctcc
     1501 tcccatattt cccatcatag agaataggaa gaagaataga attccaaatg gcacaatgga
     1561 tacgagtaga ttaatccata taccacttga actttcatgc ttaacagtta cttctgcttt
     1621 atggtcagta gcaagttttt gcaattctga tacggtagta tctgcaggaa gaatagtgct
     1681 ggtaaatttc tctaccttag taacagatgg cgtgaaaaac tgaatacctg ttccttcttt
     1741 acttgtttta ggatttttat agacaccaga aacttcgata acactaccat ttggttggta
     1801 agttaattct tttacattac catcggtaat ttcttgtacc aactcagtat agttgatttg
     1861 ctgacttcct cctgagttat tcccagaata gaaatactgg aatcctgtca caaggaaaaa
     1921 gataaataat aaccatagaa aaggattttt aattaaacca ttattttgtt ttttcattaa
     1981 agattattct ttctaatttg aatacacttc ctctttcaat actccaatat aaggaagatt
     2041 acgataattt tctttgtagt ctaaaccata acctactaca aactcatttg ggatagtaaa
     2101 gcaggtatag tctgcctcaa tttctacaac acgtccttct ggtttatcca acaaggttgc
     2161 aattttaaca gaagctgctt ctctttcttt aaacatatct cgcaaattct tcaaagtttg
     2221 acctgtatca atgatatctt ctacaaatag aacatgtctt cctttgatat cttgagtcac
     2281 atcttgttta atattgataa caccactact tgctgttcca ccatggtagc tagaaaccat
     2341 catgaagtcc atttcaatat gtgtatcaat atgtttgacc aattcagcca taaaaggaat
     2401 agatcctttt aaaatcccaa ctaagattgg attttttcct gcatagtctt tagttaattg
     2461 agcacctagt tttttagctg cttctgtaat ttcatcgtgt gaaacgagga cttttttaat
     2521 atcgttttct aacatttttt acctatctat tttttctata taaagtacag tgttcattat
     2581 atcatttttc gtttttttac tcaaattatt ggtcgcaatt cccaaaattg agacaatttc
     2641 accaaattgc tcaataataa gagcagagtt tctcttttcc atagggattt tcaaatcaat
     2701 aaataaacgt ctgagttttt ttctatgccc attttgaatc aaaacatctc ctgtttttcg
     2761 atgacgaatg tgtatggatg tttcacgtga aacaggtatt tgttgaatta attcaccttc
     2821 taatggaagt ccaaaggaaa ataaatatcc ttgataagct acctgatttt gatagtgtaa
     2881 cacaagttca tcttcctctt catcagcctg cggactgatt ttacaaatct gaaactgttg
     2941 gtactctttt atcaattcat agccattttt aatcggatga cgatactggc ttttagattt
     3001 taaaatctgc tgaacttcag caaactgagc ttttgtaaga ttcaaatctg gaaaacgatt
     3061 cagataagtt tgaagtaaaa ctctttgtgt agactcagag taagaaaata actgctgtaa
     3121 attttccaca ttaatattgt tagataattc agctattgcc aaatcataat ctaaaatttc
     3181 attgccgatg cctaagattg catccctaaa tcgaggattt tctttttcca attctggtaa
     3241 gtaagaattt cgaatacgat ttcgaaaata atgattctcc tgatttgatg tatcttcaaa
     3301 gtgaaaaatt gatggaaagt cttttttctg aaaatgcaag aagggacgaa tgatttctat
     3361 ctctccgact acttgcttct ccttaattcc tgatagatag cgcaagcgag ttcctcgaat
     3421 caagcgcatc aaaatcgttt ccacctgatc atcagcatgg tgggcagtga ctaaagctgt
     3481 cgcacctgtc tttttcatga cctcttgaaa aaaatcataa cgaaaatttc gtgcacgcgc
     3541 ttctgaaaat tctcctgaaa aattgctgat ataaatagga agctctgctt cagcagccaa
     3601 cttccttaat tccttttctt cccaatctga ttcaattctc tgcttatgat tcacatgagc
     3661 tagaatcaat tcaatctcta actctttttg ataagtagac aataccttaa atagaaacat
     3721 ggaatctaat ccaccagaaa gagctagaac cgccttagca tgctttttga aatatccctt
     3781 cttgagaaaa tgatttaaaa aatctggttc cctcatttta gaacctcata aacatccttg
     3841 gctatcttag aaatcgtatc ataatcagaa ttcttagtga aaatagaaag aataaatgga
     3901 gaatctgcat agacaacacc cgtatcatgc ttaaattcat ccgcatctcc aattttatga
     3961 gctactttaa cagaaacacc tttggcaatt cgctgactat caaaatctgt tttagtcaaa
     4021 gactctagca caaatccatt ttgattataa atagcttcca taaacttccc ggccatctta
     4081 gaagaaatca atttttcttt tggatcccaa tcatctccca taatggcaga catcttggat
     4141 ttgaatgtgg catcagattg gtttgaaatg taatatccca atagattatg agctacatta
     4201 tcagattctt ttgatacttt cgtaattaaa tcctttaaag aatattcttt attatcttct
     4261 tttttaggaa gactaccact tccctctggt ttataagaac ctggaaaatc attgactgca
     4321 gatacgtatt ttacagtcgt atctaactga taaagaccct catttatttt ttcttgcgta
     4381 taatagagat aggagagttt caaaacgctg gctgcataca tcttttcatc ttgattgata
     4441 ccagcttctt ttccagtagt cagttgctta acataaatag agaaagaatc tttctgatat
     4501 ttttcagata acatttcttg aactttactc atccgattat cttcttcaga agttgattct
     4561 ttagctaccc atccagcctg atcaatatgt agaaattctc ttccttctac aaacatggtc
     4621 ttgtcgattg atacttgcga ataagctgat aaggatgatt tcacttcttt taaatcataa
     4681 ggactattgt acagtttaaa gtcagattct aaccatgctt tttttattgt tggagttacc
     4741 tctgattgat catataaaaa tcgtttgtcc gcagctataa attgatgatt tgatagctta
     4801 aatactggaa ttccttgttt atttaagcgc cactcggtta tttgaaaact tgttttggga
     4861 gtcaatttcc cagattccac tactaaatct tcattcgcat aaacaggaac ctctccataa
     4921 accatgggag aacttaattt ttctctaaaa taaatactaa agtcagattg tgaaaggtaa
     4981 taaatttctt tcgaagtata gacgacttct ttttctgtgc taacgacttt tgaaatggtc
     5041 aaaaaacttg gtagcaacaa aataattaag aatttacgca ttcttccttt ccttttcttc
     5101 ttgtaaacgc aataattgat ttttatcagc caattcttcc agcttttcat ctgacaaact
     5161 caaaaattgc tctattacgt ctaataaatt ttccatttta tcacctttga agcaagtcag
     5221 gaatcgtata aactttttcc ctcgacttag aataatagta cttcgctcgt gtatatttag
     5281 cagcataatc ttcatctttc aacttggtag caaatgctgt ctccttatcc ttttcatcac
     5341 tcaaagtttg atactgagtt tgcaagtctg ctaattgctg acgtctttgg agtaattgct
     5401 gataactctg cgctaaatta aaagttggca agataaataa tagcataatc aaaatcaata
     5461 cccctcccat aaaacgattc cgtttttgtc gttctttcat caggtagcga cgacgttggt
     5521 attcattttg aataaaagaa ttattcaatt gtacaatatt tttagacatt ttcttctacc
     5581 cgtgtttcac tgataatttc atacattcct gctgcatctt ctttttttgt actatctttc
     5641 atctctagta cttttacaag cagcaactta ttgccaaagc gaatttcaac ttggtcatta
     5701 actttcaagt ccgttgaact tttggccaag attccattaa ccttgattct acctttatct
     5761 gctacttcct ttgcgactgt acgacgcttg ataattcgcg atacttttaa atatttatct
     5821 aatctcatcc ttattacctc aatttattat tgtaccattt ttatctattt tatagaagaa
     5881 aaatatcaaa tggaattttc ttccttaaac tcttttatct ctaataaact ttctccaaaa
     5941 atcagcagac cttctaaaat ttcataatct ttcttatttt ggacatcaaa tacaagctcc
     6001 attaatccct tattctcagc gatgcctgct tttaagttcg ttacggataa agctttaaaa
     6061 taatcttgag ctaaaaacag ccgttgagtg actttttcaa attgaattgt aattttatta
     6121 tcttttcttt ccacacgttg aacaaagacc ttgtccaagt atgatttaac caaaccaatc
     6181 tctaaaagat aggctactac atctgggtat tctccaaaac ggtctatcaa ctcctcttgt
     6241 aactcttcat aattgacacg gttgtcaatt tgacgaattt tcttgtaaat ttcaatctta
     6301 tgtcgttgat cagaaatata agtatcagga agataggcat caatttgcaa aatcaactca
     6361 gcattccctt tggttcttgt gttagcgtta gcattaccgt ttcgtttagc aatagcttcc
     6421 tctaataact gcgaatacaa ttcaaaacca acagaatcaa tgaaaccaga ctgggatttt
     6481 cctaaaagat ttcctgctcc acgaatcgaa agatctcgca ttgcaatctt aaagccagag
     6541 cccaattctg taaatccttt aatcgcttct aatctctttt cagagacttc actgattgat
     6601 ttttctggac gatacatgag ataagcataa gcaatacgat tactacgacc gactcttcct
     6661 cttaactgat ataaggttga caagcccata tggtccgcat tttcaataaa taaagtatta
     6721 gcatttggaa tgtccacccc tgtctcaata atagtagtcg tcaccaagat atcgtattgt
     6781 ccctcaataa agtctaatag agtattttcc aactggactt cactcattcg accatgaaca
     6841 tatccaatcg aagcctccgg aatcaactcc tgtaattctg aaaccttctg aacaattgtg
     6901 tcaactttgt tgtaaagata ataaacttga cctccacgct ccatttcacg caagacagca
     6961 tcacgaatga cactatcatt cttttccaaa acataggtct gaacaggata gcgattagtc
     7021 ggcggagttt caataacaga taaatctctg attcccagca tagacatatg gagggtacga
     7081 gggattggcg tagcggtcaa ggttaggaca tccacttgtt tcttcagttc tttcaaagtt
     7141 tccttatgct tgacaccaaa tcgctgttcc tcatcaataa tcatcaagcc caaatcagca
     7201 aacacaacat cttttgacaa aacacgatgt gttccaatca aaatatcgac ttgaccgttt
     7261 ttcaattttt caagtgttgc agtctgctct tttttacttc taaagcgact caacacatca
     7321 atattaactg caaaattttg gaatcgttcc ttaaaattcg tatagtgctg ttgcgctaaa
     7381 accgtcgtcg gaactagaat gacaacctgt ttgtgatcat tgactgcttt aaaggctgca
     7441 cgcatagcaa cttcagtctt tccaaaacca acatccccaa ctaaaagtcg atccattggc
     7501 tgagaagcct gcatatccct cttgatttcc tcaatactac gaagttgatc atccgtttca
     7561 acataaggga aagcatcatc aaaggcatct tgatcatcat catcagctga gaaagcaaaa
     7621 cccttcaact gactacgttc agagtagagt ttgattaaat catcagctat atcctctacc
     7681 tggttcttaa ccttttgctt ggccttttta aaatgaccgt catttaattt attgagtttt
     7741 ggagctttac catcacttga aatatatttg gacagtagat gaatctgttc cacggggata
     7801 gaaatttgat caccattttg gtattggaca ctgacataat cgcgatgaat tcccttgatt
     7861 tcaatggttt caattcctag atattgacca atcccatgga tatgatggac aacatagtcc
     7921 cctttttcaa gttcattgta atcttttaat ctctctgcat ttgaaacatg ttgtcttcga
     7981 aaacgacgct ttaatttctt ttgaaaaatc tcatgttcag ttatcaataa aatcttttca
     8041 tctacaaaat gaaaaccatg tctgagatta ccctctatta agtttacaga ttctttacag
     8101 atatttgtct tatctctaga atccaattta atctgatatt cctctaacat atcctccaat
     8161 gttttacttc ccattgaatt gctagactgc agaataatgg tgtaatccat ttttttatat
     8221 cgttcaattt cttcttttag aaaagaaaac tgattgaaaa attcctgcat aggatattga
     8281 ttgaattgat aaattttgtc aaatttgaga tttcctaaac ccttttgaag attagagaaa
     8341 aaggtcactg gactttgttt tttatagatt tgttcaatat cagaaaaata ctgcatatca
     8401 gaaaatgctt tactattctg taattcttct gtaaagtact gcgctaagtc tctttcaaag
     8461 acttcatact gattcatcaa tttttgataa tcatcaaaga atattggggt atctttttca
     8521 atataatcaa agacagtcca tgtcttatca tagcacaaag ataaaaactt ccgagagtct
     8581 gcatgacttt gtttttggtg aaaacttgaa agaatttctt ctaggtatga tttcaaaata
     8641 ggtgataaag tttttgaaat ttgtttttct aaagctgact gtcctcgttg ataatccttt
     8701 tctctcaaaa gcatatcact agctggaaag atagtgagtt ctgtcttatt ttctttcgat
     8761 aattgtgttt ctacttcaaa tgacctgata ccatcaattt catcaccaaa aaactcaatt
     8821 cgacaaggtt ctaactggga tatttcaaaa atatctaaaa tatctcctcg aagactaaat
     8881 tcgccctgag tttgtacttg agtaactttt cgatagccat tttcctttaa ctgatggata
     8941 aacgcgtgtt gatcatattc ttcaccaact gagattttta caatactatc tttgaatgca
     9001 ttgggagacg gtaaaatcaa tcgacttgct acgatattac aaactaaaat ccctttctta
     9061 gatgaatcag tcaaaaaacg caaggcttca acccgtgaaa taattttttc ctgtgaagac
     9121 atcaaaaact ccaccatagg agcatcatct accaaaaatg gatagacgag ttcctcaccc
     9181 aagatagata taagatcact aacaagtcct tctgcttctc cataagttga cgtcaataac
     9241 acaatcctat cttctttttc taaactgctt gcaattgcaa gagccttagt agatgttgat
     9301 aaaccaagta ttagttgtct tttcttatct gttaaatttt gatgccattt tttaatctga
     9361 tcattttctg agaataaatc taataaggtc accatttatc cgttatacct ctgcattgtt
     9421 ttctcaaaat ttttctcttg taaatagtag tttacagaat cgtcaacttt gtcaatagac
     9481 tgtaaaatac cgatataatc atccctgtca aacttactca aaacatgatg aacaactgac
     9541 ataccatttt taggtcttcc aattccaatc ttaacacggt taaagacctg agttcctata
     9601 tgttgaataa tagacttgat accattatga ccacctgctg agccttttgc tcttaaacga
     9661 attttcccaa cttccatgtc aagatcatcg taaatgataa gtaaatcgtc aatatccaaa
     9721 ccatagtaag ttaataaagc atgaactgct tttccacttt cattcataaa ggtcgttggt
     9781 ttaaccagat aaattttttc tccatttagg aaaaaggatg ctaggtcagc ttgaaatatc
     9841 ttatcgtgtg taaaagtgac attctgtttc ttcgctagtt gatcaatcaa cataaaacca
     9901 acattgtgtt ttgtttcaaa atatttatcc cctggatttc ccaagcctac aagtaatttg
     9961 gtcatttatt tttcctttca aaagccaaaa gggttggaat tttttttcca acctaattga
    10021 caccatttat taatttttag acattaaagc ggaattccat gatatcgcca tcttgaacga
    10081 tatattcttt tccttcttca cgcaagcgtc cagcttcttt tacggccttt tcagatccgt
    10141 atttcactag atcttcatat gacatggtta ctgcacgaat aaagcctttt tcaaagtctg
    10201 agtggataat accagctgct tgaggagcct tcataccacg tttgaaagtc caagcgcgaa
    10261 cttctttttc accagctgtg aagtaagttc ccaatccaag caagtggtaa gctgcacgcg
    10321 tcaacttatc tacacctgat tctgtcaaac caatggcttc aagaaactct tttttatctt
    10381 catcatccaa ttcagaaatt tcttcctcag cacgcgcaga aataacgact acttcagcat
    10441 tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc gatagagtca ggttctgaaa
    10501 ccacatcctc gtccacatta gctacataaa gaactggttt agtcgtcaaa aggaaaagac
    10561 ctttgacaac cttttgttcc tcatctgtaa attcaatggt acgagctgat ttcccgtctt
    10621 ctaggactgg tttaatcttt tgaagaacat tgaattctgc tactgattct ttatcttttt
    10681 gcgtacgtgc catcttttct acacgcgcat atcgtttgtt cactgattct aagtcagcaa
    10741 gaatcaattc cagattaatt gtatcaatat ctgcaagtgg atctacaaag gcgtcttcac
    10801 gtccttgctc gcgcatcaca ttttcatcat caaaagcacg aactacgtga acaatcgcat
    10861 ctacttcacg aatattggcc aagaatttat tccctagccc ttctcctttt gaagctcctt
    10921 ttacaatccc tgcaatatct gtaaattcaa atgttgtggg aactgtcttt ttaggagtta
    10981 tcatttcagt tagtttttgt aggcgttcat ctggaacttc caccattcca acatttggat
    11041 caatagtcgc aaatgggtag tttgctgcct ctgctcctgc ttttgtaatt gcattaaata
    11101 atgttgattt accaacgttt ggcaaaccaa cgatacctgc tgtcaaagcc atatttctca
    11161 ttctccgttt tcatttcaat ccctaatatt ataacacaaa aagggataaa gtgctaaccc
    11221 tctaactaag ggttctcagt caataatttt attcattttt cgctcaaaat catatcgccc
    11281 catcatgaca acatgctcac aattactgca ttttattttg atatctgctc ctacacgtgt
    11341 aacttcccaa cgattagcct ttttaccagt cgacttgatt gtacaagcgt gtgatttttt
    11401 catctcaaca aaatttccaa cttgatacat actactctcc ttttcttttt cgattatatc
    11461 ataaaagagg cgagccaggc tcaacctctt tcacttaatt tgtacgaact ggtgtaatga
    11521 gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt aaatggacga acagctgaga
    11581 taaagctaat ggtcaccttt tcgctattta aagctttaag agaatcaatc aagtaagttg
    11641 ggttgaaact aatggtcaaa tcttcaccag taacctgatc agtatcgatt tcttcgttta
    11701 ctttaccaac ttctggagag tgaacatggg cgctaacaac cccatcctta atttcaagtt
    11761 tcacagtacc attttgagtc gcacttgata aaagacgggc acgctccatt gactggcgta
    11821 agtttaccac attaaaagta atagtagtgt taaagtctgt tggaatcaag cgatctgtat
    11881 caggatagtt tccttctagg agacgagtat agaagctaat attttcgctt ctaaagagga
    11941 tttggttatt ggcaaagaaa atctctacag tttcgatatc atctgtaaat accgctgaaa
    12001 attcgcgtag agaacggcta ggaattacga catcaaaatc atcactattt ttttcaagag
    12061 tcaatttttt ctggcttagg cgatgagagt ctgttgcaac tgtttttaac tctttgtgtt
    12121 gactcaatac gaagtggaca cctgttaaaa tcggacgact ctcttgtgta cttgcagcaa
    12181 aggctgtttc attaataatt ttcttgagta attttgtttc aagtattaaa ggagtgcttg
    12241 ctgaaatttc ttggattcgt ggatattgtt cgctatcttt tccttttagg gtaatttctg
    12301 atttgccact ggttaaaaca atttgatttt gttcaatttc tttaaaatca agagtcacat
    12361 caggtaaact agatactaca ttgataaaga aagaagcttc aagaaggatc gaacctaaag
    12421 aagtaattaa caaaccagca tcttcatttt tttgagaaat aaaattttca attgaaattt
    12481 gaccatttga accaattaaa gtaatacctt cattggtcac gtcaattttt actgttgata
    12541 aaataggaat ggcattttta gaactaatag ctctcttagt agtatttaat gcttgtagaa
    12601 ataaattttt attaattgaa aaatgaatca tggattctcc tttatttatt tttagtatta
    12661 gaaagataat agtaataata gagtctgtga aatctgtgga aaacagcctt taaacaagtc
    12721 atatcaagtt ttttagcttg tttaaaaaat gtggataaaa aagataaaaa actaaaagtt
    12781 atccacaaat tatttgattt tctttttgat tgattcaatt tctaaacgta aattatcgtc
    12841 ttgatcaatc aaagatttta ttttggcatg ggcatgaatg actgtggtat gatcttttcc
    12901 cccaaattcc ttcccaattt ttggaagact attatctgtt agttctctag ataaatacat
    12961 ggctacttga cgggccaaaa caatattttg aaggcgtcta cttcccttca tttctttgat
    13021 actaacacca taaaagttac caacttcagt ttggatttta tcaattggga tgacgagcat
    13081 ttggctaaca tcttgtttgc gggctctaat ggcttctgca gcaatatcaa tagtgatatc
    13141 cttgattttt tttactctgg caattaaagt gatgtcgttg atggctccct caagatctcg
    13201 aacatttgaa tcaaattgcc cagctaggta ttctagagta tcactttgga aattgtagcc
    13261 taaatgttcc gtcttacttt gtaaaatggc aatacgtgtt tcaaagtcag ggggtgtgat
    13321 agtttgtgtc aatccccaac taaaacgcgt gacaagcctc tcctcgagcc cttctagatg
    13381 ttttggacta cgatcactcg ttaggacaat ctgtttttgc ttgtcatgaa gggcgttaaa
    13441 ggtattgaaa aattcttcct gagttgcgac tttttttccg ctgagtgact gtatatcatc
    13501 gattaacaaa agatcaagac tacgataggt ctttttaaac ttttccattt ccccaagtct
    13561 taggtgatca agaaagtcat taataaagct ttcggcaggg atatatttaa cacgcgcatt
    13621 aggaatattt tttagaattt catttccaat agcgtttaat aagtgagtct taccaaggcc
    13681 tggtcctcca tagataaaaa gagggttata ggtcagagcc aaatcttcag agacagctaa
    13741 agcggctgat acagcccaaa catttccatc cccttgaata aagttatcaa aggtatactt
    13801 ttcttttaat cccgtatctg aataaggaat agatactaac tttggactat agtcataaag
    13861 agttaaattt gtagcttctt caacttgtga gctagtcgta tcttgaggtt tggtgaaaat
    13921 atagtgggga gttatttcag cgtcataaat ttcaaaacca gctactacaa taatatcttt
    13981 tagttgtttt tcccagacca tttccatttc agagcgaggt agaaatatag tggcaacatt
    14041 ttcctctacc ttgatgagtt cagcttgaat agcatagaaa tcatacatgg atcgagtcag
    14101 tctttcttgt gcaaattcta atatacgatt ccaaaattgt ttttctttca atcctttctc
    14161 ctcctttact atttaaaagt ttaatactag agatatttta ccatagatag caagaatttt
    14221 ccacaagctg tgaaaaataa tccacaatgt taccaaactt tatccacagg ttggggataa
    14281 aagaagaaat tattgattta ttaagctttt tatcgaaaaa catagtggat aaccttgtga
    14341 gataaaaaaa taaaagaaca gccttatttc aggctgttga taattctact atattcttct
    14401 tgatttgaaa aagaaataat gatttttcca ctgtcttttt tagatagttt aatttctaca
    14461 tctaatccga gtagttttct taactgtttt tcttcatttt gtatgaaatg attagttttt
    14521 tgctgtttct tttgtttttt ctctgtcaga agagtttcta acttccttac agaaatatct
    14581 tcttctataa tccgttgaaa gaaatagtct tgttgttcct tatttaaccc aactagggaa
    14641 cgcgcatggg cttgtgatag tttgccattt tctacttctg agagaatctg ttctggcaag
    14701 gaaagtaaac gaatggagtt gctgatatat ggacgagact tgcccatctt atctgcaatt
    14761 tcagcatggg tgaatccttt ctctacgaga gattcatagg cgcgtgcttc ttctattggg
    14821 tttaaatttt ctctctgtaa attttcaata atggactgga ccatcatctc ttggtctgaa
    14881 atctgtttaa caacagctgg gatagaccgt agaccagcta aaagtgaagc ccgatagcgt
    14941 ctctctcctg caaggatttc ataaccaata acaggagatt gacgaacaat aatcggttga
    15001 atgaccccat tttctttgat agactgtgct agttcatcta gcttttctct atcaaattct
    15061 tttcggggtt gatagggatt tttttgtata tctgtgatag aaatcatttc aaatttttcc
    15121 atgattctac actaacacat cttttctctt atgtaaagct ttctttacat agatgtcaat
    15181 taagattcta aatcacctga actcttgtta agtttgatag aggtagtttc ttctttcccg
    15241 ttacgatagt aggttatctt aatggtgtct ccgatagaat ggttgtaaag agcactttgt
    15301 aagtctgttg atgaagcaat ctctttgtca tctacttttg taattacatc gtatttttca
    15361 aggtgaccat tggcaggcat attactttgt accgaacgaa caactacacc agatgtaaca
    15421 ttacttggaa tattgagtct tctgatgtcg cttgtactca cattagataa attaaccatc
    15481 tggattccca aagctggacg cgtcactttt ccgttttttt ctaactgttc aataatattg
    15541 atagcatcat ttgcaggaat tgcgaaacca agaccttcta cagatgttcc tccatttgta
    15601 gcaattttac ttgaggtaat tccgataacc tgcccttgaa tattgatcag tgggccgcca
    15661 gagttacctg ggttaatagc agtatcagtt tggatggctt ttgtagaaat agcttgtcca
    15721 tcttccgatt ttaaggatac atttctattg agactggata cgataccttg agtgacagta
    15781 tttgcatatt cagaacctaa cgggctaccg atggcaatag cagtttctcc tacagttaac
    15841 ttactagaat caccaaactc agctactgtt gtcacttttt ctgaagagat ttttacgaca
    15901 gcaatatcag agaaagtgtc agctccgaca atttctccag gtactttagt cccatctgac
    15961 aatcgaatat ctactttgct ggcgccattt ataacgtgat tgttggtgac gatgtaagct
    16021 tctttatcat tctttttata aataactcca gatccttcac tagagattcg ctgagaatct
    16081 gtgtcagtat catcattgcc aaatacgcta ttttgtctgt ttgccgaata agtaataaca
    16141 gaaacaacag catcttttac tttgttaaca gcctgtgttg ttgaattttc gttcttatag
    16201 gcagtttgtg taatagtact attattgtta gagttgttta cactactttt ttgagttagt
    16261 tgagttattg aaaaactacc caaggctcca ctaaaaaagc taatgacgat aacgactaat
    16321 aattgaaacc attttttgta aaatgttttt agatgtttca tatttgcctc catatgtttg
    16381 aattactgaa agtataaact gactagctta attataactt aaacacaaaa gttttacaca
    16441 aactgtggat aactcttttg aaactgtgat tttcttaatt gaaatctatt ttttattttg
    16501 tgaataagat gtgaaaaaat agagaatatg ttagaataga gtcatgaaaa ttaaagttgt
    16561 aacagttggg aaactgaaag aaaagtattt aaaagatggt atcgcagagt attcaaaacg
    16621 aatttctaga tttgctaagt ttgaaatgat tgagttatca gatgaaaaaa caccagataa
    16681 ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa ggtcagagaa ttttatcaaa
    16741 aattgctgac cgtgatttcg ttattgtgtt agccattgaa gggaaaactt tcttctcaga
    16801 agaatttagt aagcagttag aagaaacttc tataaaagga ttttctactc ttacttttat
    16861 tattggggga agtttaggat tgtcatcatc tgtaaaaaat agagccaatc tttctgtcag
    16921 ttttggtcgc ctaaccttgc ctcatcagtt aatgagacta gttcttgttg aacaaatcta
    16981 tcgcgctttt acgattcagc agggattccc ctaccataaa tagaaaattg acttttaatt
    17041 gaatttttgg tagaataatt gtgttaggtc tcatagctca gctggataga gcattcgcct
    17101 tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca atataatagc aaagctggga
    17161 attttcccgg cttttttctt aaaaaagtac actttgggag aaaaaaatga cagttgagag
    17221 aattttatct aaagtgaaat tccattttgt ataatggttt ttgtaagtta gcttacaaga
    17281 aaaaacattt taggagattt tattatgaaa aacacagtta aattggaaca gtttgtagct
    17341 ttgaaggaaa aagacttaca aaatattaaa ggtggggaga tgaggatttc aagaatcatc
    17401 cttgattttc ttttcctacg aaaaaagtaa tgaaataagg agaaagagta atggatttac
    17461 ttggatttgg gacagttatt gttcattttt taattattag tcacagttac cgtttaattt
    17521 gtaaaggtcg aataaataga aaagaattat acatttttgg tgcttataca ttactaactg
    17581 aaatagtact tgaattttcc ttttatcttc tatatttaga taaaataggg attgaaagat
    17641 ttttatttcc tttgggctta tattcctatt ttcgatggat gaaacagtat gagagggata
    17701 gaggactatt cctaagttta ctactatctc ttttatatga gagcactcat aactttctgt
    17761 ccgtaacttt ctcctctata acaggagata attttgtttt acaatatcat ttcccattct
    17821 ttttcgttgt gacggtgtta acctattttg ttacattaaa aatcatttat tatttccatt
    17881 tggaactagc ctattttgac aaggactacc tttatccttt cttgaaaaaa gtattttttg
    17941 ctttactatt gctacatatt gtatctttcg tttcagatat ggtaagtacg attaaacatt
    18001 tgaatagttt tggaagtatt ttgtcatcta ttgtctttat ctctctcctt ttgaccttct
    18061 ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat tgcttttaag cagaagaaat
    18121 ttgaacagaa acatttacag aattacacag atgaaattgt tggtctgtat aatgaaatcc
    18181 gtggttttcg acatgattat gctggaatgc ttgtcagcat gcagatggca attgacagtg
    18241 gtaatttaca ggaaattgac agaatttaca atgaagtttt agtcaaagca aatcataaat
    18301 tgcgttcaga taagtacact tactttgatt tgaacaacat agaagactca gctttacgaa
    18361 gtttggttgc tcagtcaatt gtctatgctc gaaataatgg tgtagagttt acactggaag
    18421 taaaagatac gattaccaag cttccaattg aactattgga tttggttcgt atcatgagcg
    18481 ttttattgaa taatgctgtc gaaggatcgg ctgatagcta taaaaagcag atggaagtag
    18541 cagttattaa gatggaaact gaaacagtta tggtgattca gaattcatgt aaaatgacga
    18601 tgactccttc aggagatcta tttgccttag gattctccac taagggaaga aatcgcggag
    18661 tcggattaaa taatgtgaaa gaactactag ataagtacaa caatattatt ttagaaacag
    18721 agatggaagg cagtacattt agacaaatca ttagatttaa gagggaattt gaatgaaagt
    18781 tttaatttta gaagatgtta ttgaacatca agtgagacta gagagaatat tggatgaaat
    18841 ttcgaaagaa tcgaatattc caatatcata caagacaacg ggaaaagtcc gtgaatttga
    18901 agaatacatt gaaaatgatg aagtaaatca gctttatttc ctagatatcg atattcatgg
    18961 aattgagaaa aagggatttg aagtggctca gctcattcgt cattacaatc cttacgctat
    19021 tattgtcttt atcactagtc gatcagagtt tgcgactcta acctataaat accaggtatc
    19081 agccctagat tttgttgata aggatatcaa tgatgagatg tttaagaaga gaattgagca
    19141 aaatatcttc tacacgaaga gtatgttact tgaaaatgaa gatgttgtag attatttcga
    19201 ctacaattac aagggaaatg atttaaaaat tccttaccat gatattttgt atattgaaac
    19261 aacaggggta tctcataaat tgcgcattat tggtaagaat tttgcaaaag agttttatgg
    19321 taccatgaca gatattcagg aaaaggacaa acatactcag cgattttatt ctcctcacaa
    19381 gtcatttttg gtaaatatag gcaatatcag agaaattgat cgaaaaaact tagaaattgt
    19441 tttctatgaa gaccatcgtt gtcctatttc aagattaaaa attagaaaat taaaagatat
    19501 tttagagaaa aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata
    19561 tctgctacag atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt
    19621 aacacgggtt cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg
    19681 catgactgtt aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg
    19741 gaacacagct gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa
    19801 gtctgttatt tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc
    19861 aaaaagtgca tgagttagat agatgctact atattctaat tcagtggtat ttagattcag
    19921 ttgcataaat cgcttttgta aatctatact gagcatgata tgaagtttat ttcgtaagaa
    19981 attttggatt tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc
    20041 tagatattca aagacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat
    20101 atattcaaat gtatggaata gcttgctttg atagtgctca atcacatcat acttatcctt
    20161 atagtgagta tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga
    20221 aattttatca aatggctgtt ccatcagtaa ttgtaccata gcattttcaa tagttcgctt
    20281 tgtttttaag cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata
    20341 tgtctaaaaa tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat
    20401 taaaatttta gacaatatgt ttaaaaaagg agaaactaag tttaaagaat ggaaagcaat
    20461 ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt tctcttattc cagatctgta
    20521 caatatcata tttttgtcat caatgtggga ttcatatggg caattgtctg acttacctgt
    20581 ggcagttgta aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa
    20641 agacatggtg tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga
    20701 ggaaggaaag aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga
    20761 tttatctgaa aaaacaacta cattatccaa tattcaatcg acagcagctt atcaatcatt
    20821 gacaagtgag caacaaactg agataagtga ttctgtatct caaaattcaa ctgatagtat
    20881 tcaatcggct cagtcaattg tagctttagt acaagattta cagggaagtt tagaaaactt
    20941 acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa tctaatcaag tatcacctat
    21001 tacttctact tctttgatag gattgtcaag tggattaaca gagatacaag gagatgttac
    21061 tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt gtaaacgcat atactacagg
    21121 tgttgataaa gtttctcagg gcgcaagtca actaagtgaa aaaaatgcca ccttgacagg
    21181 tagtttggat aaactagttt caggctcaaa caccttgaca caaaaatctt ctagattgac
    21241 agcaggagtt ggttaattac aatcaggatc tgggcaatta gcagacaaat ccagtcagtt
    21301 actttcaggt gcttctccat tagagaatag agctaataaa ttggcagatg gatctgggaa
    21361 actagcagaa ggtggaacaa agttaacttc tggattggaa gatttacaga caggacttgc
    21421 ttctttagga caaggactag gtaatgctag tgatcaactc aaatcagtat caacagaatc
    21481 taaaaatgca gagattttgt caaatccact caatctttca aaaacagaca atgatcaagt
    21541 tcctgtaaat ggaatcgcaa tagctcctta tatgatatca gttgctcttt ttgttgcagc
    21601 aatatcaaca aatatgatat ttgcgaaatt gccttcagga cgtcatccag agagccgttg
    21661 ggcttggttg aaatcttgag ctgaaataaa tggtattata gctgttttgg caggaatttt
    21721 ggtatatgga ggagttcagc ttattggttt aactgctaat catgagatga gaatatttat
    21781 tctcatcatc ctaacaagtt tagtattcat gtctatggtg accactttag caacgtggaa
    21841 tagccgtata ggagcttttt tctcacttat tttgctttta ctacagttag catcaagtgc
    21901 aggtacttat ccacttgctt tgacaaatga tttctttaga tctattaatc cctggttacc
    21961 aatgagctat tcagtttcgg gattacgaca aacaatctct atcaacaagt cattttccta
    22021 gctgtcatac tagttctatt tactagttta ggtatgctag cctatcaaca taagaaaatg
    22081 gaagaagatt aaaaaaatcg accgattaac tggtcgattt tttatgcctt agatgacttt
    22141 cgtctgtgat tatagattcc aaatagtaag agagaagtaa aggaacagat tgctccagta
    22201 ataaaaccat tgggaatgaa ggaaagtgta atagttcctt tccccttggg aatgtcaact
    22261 ttcataaatc cagtttgagc ttgtttaatt tctattttct taccatcttg gtaggcagac
    22321 caacctttgt cataaggaat ggtgaagaaa atagatgtat cttgttggac atcatatgta
    22381 gcaaaaacct tgtttttaga agttgatact gtgacaggtt gttctttaat tttttgaatt
    22441 gcctcggtga aagttttggt atctaaacga tagaaggtag gagattcaaa tgatacttgt
    22501 gaatttccag ggaaactaac attgatattg aaagtttttt tctctttagt atatcctaga
    22561 ttaaagaagg agaagacatt atcagttgta aaagtctttt tttcaccatt tacaaggatg
    22621 tcaaccttct tttgtttatc gttagaaaag tgaaggttta tgaaagagag ataaacttgg
    22681 ctgttttctg gaacttcaat ttgatactgg attgctgcat cttcatttga agaacttgtg
    22741 acactaatca aatcattagt attttctatt ttttctgttt tttcataagg tattggagaa
    22801 aaataatcaa aattgacgtt agcaagttga tttaaaaatg aggcctgatt atccaaggta
    22861 tgttcattga acttgacatc attgtaaaca gattgactag caactgcaat cggaagagag
    22921 tattgatttt catatagggt aagattatct ttttgataga tatctttaaa gccatactta
    22981 tcaataggac tgtctgagat attgtactgg ataccaaata aactatcagc caaaatacta
    23041 ttatttgcat atcggagatt gagattagtc ccagaggatt taaaaccaag tttatctaaa
    23101 gtagagcttg atgaacgatt tcgaacagat gaaaattgag agattccatt gtagttgaat
    23161 ttcatactgt catttcctgt ctgagtttgt agtttttcag tacgagtaaa ttgatttcca
    23221 atatatgttg agaaagattc catagctggg atatctcgac tataagcact tcgagaagca
    23281 aatccccatt ccttagcaat tccgtccatt tgagatgaag catttaaact catttcaacc
    23341 agtataaata aagagattag aatggcaaat agattcacag atataaactt tttgataact
    23401 gcaaggagta aaagagaata gacaaccaaa aattcaagag taagcagaat attcaaatct
    23461 gttaaaaaag aataatgcga ttttagatag atggtagcta aaaatcctgt tactacaaga
    23521 aaaagcgaaa ctaaaaaatt ccagacttta agttctttca gacgctttaa gacttctgct
    23581 gctgtgtaaa ttaacaaggt agagaaaatc caagcatagc gatgtaaaaa catgtttgga
    23641 gtatgcatgc cttgccaaaa taagtcaaga gcttctatgt aaaagcttgc aattagaaat
    23701 gcaaagaata ttacatatat gagtttcacg tgaaacttaa tagatttcag cgtaaaaaat
    23761 aaaatggtca aaataaaggg aaatagtcca acaaaaatca ttgggatggc cccatacttt
    23821 gttgtgtcaa aggaaccaat gaattgctta gcaaagagat caagatacca gctactttca
    23881 gtttgaaact ttgtaacttc agtcaatttt tccccatgtg tctgtaaatc aaatagagtg
    23941 ggaagagtca taatcaaact agccatacca gctaaaaagg agataactat gaaatcaaga
    24001 acagatgatt ttcgagtctt aaagtcccac gaaatttgac agagatacca gaaaataaga
    24061 aacaatactg tcatatatcc aaaataataa ttttgaataa ataagattga cagacttgta
    24121 aagtacaata ggagtttctt ttcagttatc agtagatgta aaccagttat aattaaagga
    24181 atcaagataa aaacatctag ccaggttttt atctctaatt gactgacagt gaaactcatc
    24241 agagcatagg aagtagataa ggctagtttt aaagtctgag ggatagattg aaacaattta
    24301 ttcaaactaa aaaaggttga cagaccaatc aatccaaatt ttaagagagt ggtcagatag
    24361 acagcatctg gcatattcgt tagatcaaaa aagtaaacta gaggcgcgag aaaactaccc
    24421 aagtaataac tagatagggc atagaagttt agccctagac cacttgtaaa ggtgtaaaac
    24481 agactactat ttccatgtag gatatttcgt aaggctacat caaaaataac gtattgatga
    24541 aagccatctc ctaatagagg agagttgtcg ctattccagt agataccttg agatagatat
    24601 actccagaca taatcactac aggaatgatg aaagaaataa aataggttcg atatgttttt
    24661 aaaaatgatt tcatgttacc tcgtagaatg atagaaaact cagttggtta acccaactga
    24721 gttttgaagt tttatttagt ctttccaaag ttctttaact tttgcttgta cttctgcatt
    24781 ttctaggaat tcatcgtagg tttcatcgat acggtcaatg acgccatttt tagataagac
    24841 aatgatatgg ttagccaaag tttgaataaa ctcgtggtca tggctggcaa agatgattga
    24901 ttctttaaag tttttcaatc catcattcaa gcttgagata gattccaagt ccaagtgatt
    24961 tgttggatca tcaagtacaa ggacatttga ttttaagagc atgagttttg aaagcatgac
    25021 acgaactttt tctccccctg acaagacatt tacaggtttg ttaacttcat ctccagagaa
    25081 gagcatacgg ccgaggaaac cacgtaggaa agtattgtca tcatcttctt tacttgcgaa
    25141 ttgacgcaac cagtcaagaa ttgattctcc tcctgcaaaa tcagctgagt tatcttttgg
    25201 taggtaagat tgactagttg taactcccca cttgacagtt ccttcatagt caatatctcc
    25261 catgattgca cgaattaatg cagtcgtttg aatatcattt tgtccaataa gtgctgtctt
    25321 atcatctgga cgcaagatga aactaatatt atccaagata gtttcaccat caatctttac
    25381 agttagattt tctactgtca agagatcatt accaatctca cgttccgctt taaagttgat
    25441 aaatggatat ttacgactag atggtacaat ctcttctagc tcaatcttat caagcatttt
    25501 cttacgtgat gttgcctgcc ttgacttaga agcattggca gagaaacgag caacgaattc
    25561 ttgcaattgt ttaatttttt cttctgcttt agcattacgg tctgctagca atttagcagc
    25621 aagctcagaa gattccttcc agaagtcgta gtttccgaca tagagtttga tttttccaaa
    25681 gtcaaggtcg gccatgtgag tacaaacttt gtttaagaag tgacggtcgt gggatactac
    25741 gataactgtg ttatcaaagt caattaagaa gtcttctaac caagtaatcg attggatatc
    25801 caaaccgtta gtaggctcgt ccaagagaag aacatctggt ttaccaaaaa gtgctttggc
    25861 gaggagaacc tttacttttt caccgttggc caattcgctc atgttttggt agtgtaattc
    25921 ttctggaatg tttaggtttt gaagtagttg agaggcttca ctctctgctt cccaacctcc
    25981 aagttcggca aactctcctt cgagttcggc agcacgaacc ccgtcctcgt ctgagaaatc
    26041 ttccttcatg tagatagcat ctttctcttt catgatgcta taaagttttt catttcccat
    26101 gataacgaca tcaatggcac gttcatcttc gtagtcaaag tgattttgac gaagaacaga
    26161 gagacgttca tctggaccaa gagagatgtg accagtagta ggttcgatat ctccagctaa
    26221 aatttttaaa aaggttgatt ttccggcacc attagcaccg attaatccgt aagtatttcc
    26281 ttctgtaaat ttgatattga catcatcaaa aagtttgcga tcactaaaac gtagtgaaac
    26341 atcagatact gtaagcaata tttttctcct atatgtgtaa tatatttatt ctactagaaa
    26401 atacagaaat attcaaattt ttatttttca attttgtgta aattatattt acagtatcct
    26461 ttacacaaat ctgtaaaaag caaggctgat ttattttgat aaattacggt tatttcatta
    26521 aaaaaatgct ataattgaaa ggactatatc gaaggagaac aaaatgacta aacccattat
    26581 tttaacagga gaccgtccaa caggaaaatt gcatattgga cattatgttg gaagtctcaa
    26641 aaatcgagta ttattacagg aagaggataa gtatgatatg tttgtgttct tggctgacca
    26701 acaagccttg acagatcatg ccaaagatcc tcaaaccatt gtagagtcta tcggaaatgt
    26761 ggctttggat tatcttgcag ttggattgga tccaaataag tcaactattt ttattcaaag
    26821 ccagattcca gagttggctg agttgtctat gtattatatg aatctagttt cgttagcacg
    26881 tttggagcga aatccaacag tcaagacaga gatttctcag aaaggatttg gagaaagcat
    26941 tccgacagga ttcttggtct atccaatcgc tcaagcagct gatatcacag ctttcaaggc
    27001 taattatgtt cctgttggga cagatcagaa accaatgatt gagcaaactc gtgaaattgt
    27061 tcgttctttt aacaatgcat ataactgtga tgtcttggta gagccggaag gtatttatcc
    27121 agaaaatgag agagcagggc gtttgcctgg tttagatgga aatgctaaaa tgtctaaatc
    27181 actaaataat ggtatttatt tagctgatga tgcggatact ttgcgtaaaa aagtaatgag
    27241 tatgtataca gatccagatc atatccgcgt tgaggatcca ggtaagattg agggaaatat
    27301 ggttttccat tatctagatg tttttggtcg tccagaagat gctcaagaaa ttgctgatat
    27361 gaaagaacgt tatcaacgag gtggtcttgg tgatgtgaag accaagcgtt atctacttga
    27421 aatattagaa cgtgaactgg gtcctattcg tgagcgccgt attgaatttg ctaaggatat
    27481 gggagaagtt tataatatga ttcaaaaagg tagtgaaaga gcgcgtgaag ttgcgggtca
    27541 aaccctatct gaggtaaaag gggcaatggg acttcattac tttaactaag tttattttac
    27601 aagaaactat cttttctatc tcgaagaaaa gatagttttt tatttacccc tgtaacattt
    27661 gacaaatttt tatagaatgg tatgatagat acaatataaa aagagtcaag ctcaaaaaga
    27721 aagaaaagag gaaacttcga atgtctaatt gggacactaa atttttgaaa aaaggtttta
    27781 ccttcgatga tgtattgctt attccagctg aaagtcatgt gttgcctaac gatgcagatt
    27841 taacaactaa attggcagat aatttgactt taaatatccc aattattacc gctgccatgg
    27901 acacagttac agagagtcaa atggccattg ctattgctcg tgcaggcggt ctcggagtta
    27961 tccataaaaa catgtcaatt gctcaacaag cagacgaggt tcgtaaggta aaacgttctg
    28021 aaaatggagt tattattgat ccgttcttct tgacgcctga acatacaatt gctgaagcag
    28081 atgagcttat gggtcgttac cgcatcagtg gtgttccagt tgttgaaaca cttgaaaatc
    28141 gtaaattggt tggtattttg acaaaccgag atcttcgttt tatttcagat tataatcaac
    28201 caatttcaaa ccatatgact agtgaaaatc ttgttactgc tcctgtgggt acggatcttg
    28261 caacggctga gagtattctt caagagcatc gtattgaaaa acttccgttg gtcgatgaag
    28321 aaggcagtct ttctggtttg atcactatca aagatattga aaaagttatt gagtttccaa
    28381 atgcggctaa agatgagttt ggtcgtcttc tagttgcagg tgcagtaggt gttacttcag
    28441 atacatttga acgtgcagag gctctttttg aggcaggagc ggatgcgatt gttattgata
    28501 ctgcacatgg tcattctgca ggtgtcttgc gtaaaattgc cgagattcgt gctcatttcc
    28561 cagatcggac tttgattgct ggaaatattg ctactgctga aggtgcacgt gccctttatg
    28621 aagcgggtgt agacgttgtt aaggttggta ttggaccagg ttctatctgt actactcgtg
    28681 tgattgctgg tgttggtgtt ccgcaagtaa cagctatcta cgatgctgca gctgttgcgc
    28741 gcgaatatgg taaaacgatt attgctgacg gtgggatcaa gtattctgga gatattgtaa
    28801 aagcacttgc tgcaggtgga aatgctgtta tgcttggatc tatgtttgct ggaactgatg
    28861 aagctccagg cgaaactgaa atcttccaag gacgtaaatt caagacttac cgtggtatgg
    28921 gatcaattgc tgctatgaag aaaggttcaa gcgaccgtta tttccaaggt tctgtcaatg
    28981 aagcaaacaa gcttgttcca gaaggaattg aaggtcgtgt tgcttataaa ggagcggcag
    29041 ctgatattgt tttccaaatg attggtggta ttcgctctgg tatgggttac tgtggtgcag
    29101 ctaaccttaa agaactacac gataatgctc aatttattga aatgtctggt gctggtttga
    29161 aagaaagcca tcctcatgat gtgcaaatta ctaatgaggc accaaattat tctatgtaaa
    29221 aaacaatgaa aagaactcca gtgaaaacag gagttctttt acaatgttgt caatttccat
    29281 ttacagaagc tttaccatcc tgaatagtga agatacttag attttctggc agattttgaa
    29341 gatggtctaa gcttgttgtt gtgataaagg tttggattga ttgagaaatc gtttctaata
    29401 attttaactg tctagtgttg tcaagttcac tcatcacatc gtcaagcagt aatatcggag
    29461 attctgtggt aatgctttcc attaattcga tttctgctaa ttttatcgag aggacgagac
    29521 tacgatgttg accttggctt ccgaaactag catccatccc atttatataa aaagaaatgt
    29581 catctcgatg aggaccgaca ccagtattct ttttaaataa atctctggat ctactttttt
    29641 ctaaagcaat tttgaaagat tcggataagt tttgtttgtc agttatattg acagaagatt
    29701 gataggatat tgacaactct tcgatctgat tagagagttc aaaatgtttc ttacgcccaa
    29761 atgattctag tttttttatg aaatctaagc ggtgattcat tacacgacat ccataatcaa
    29821 ctagctgatc atctaacaca gaaaggaatg tttcatctat tttttgatct gattttaggt
    29881 aagtgtttct ttgctttagg atgtggttat aattggttaa gtcagataag tagattggct
    29941 taatttgccc aagttccata tcaatgaatt ttcgtcgaat cgaaggtgct cctttaatta
    30001 gttgtaaatc ttcaggagca aataagacaa cattcatgtg tcctacataa tctgaaaggc
    30061 gtgcctgttt taagtgatta acttttgtta cacggccttt ttgtgttagt tcgatttcta
    30121 ggggaatgga tccagttttt ttctgaacga gacctgaaag atgaagttgt tcctcatcaa
    30181 aatgaatgag atttttatct gttcgagttc gatgactacg cgttaaggct aaaaaataga
    30241 tagcctctaa catgtttgtt tttccttgtg cattacgtcc caaaaagaca ttcaatttag
    30301 gattaaagtc tattttcgtt tctttgtaat tacgaaaagt cttgagagat agatgttgta
    30361 gccacatgat tatctaccag ggaatcgtgg agcttgttgg cttttaggtg atgaagcagg
    30421 tttcgatttg tcttttttaa ctcccttatt catctttttg acaagtttag cgatccgttc
    30481 tttttcaact ttatcagctt ggtattcatc ttgttcttca gaagtaggtt gtgtcaacaa
    30541 gatgtcaatg ttcatgtcag ggatgtcaac tttatcgcca atacgaagtt tttttccacg
    30601 acgactctct aattccctat taaagtaaac agaatgttca gagagaaatg atttaatagc
    30661 tcctccgcta tgtgtaattc caagttcttt gagtagtgct tggagggtaa taaattcttc
    30721 aaataatttg tattccataa ttcacctcaa tctttggtat tataccatat tttcctaaaa
    30781 atagtgagag agacagcgag aaatgtaagc gatttttatt tcaaaagtgt tacagggaac
    30841 aagaaaattt caggttttcg tgatataata gaagtctgta tataaggagg taaatcatgg
    30901 agttagtgca tggaatttca acacatttta tccaatcaaa aaagtttaaa acaaacaaaa
    30961 ttaccgtgcg ttttaccgct ccattatccc ttgatacgat tgcaggtcac atgttgagtg
    31021 caagtatgct agagactgct aatcagatgt accccacttc tcaagatttg aggagacact
    31081 tggccagtct atacggtaca gatatgtcaa ccaattgttt cagaagaggg caaagccaca
    31141 ttatagaatt gacatttacc tatgttcgtg atgagttttt aagtaggaaa aacgtgctaa
    31201 cctctcagat tttggaactt gtaaaagaaa ctcttttttc acccgtagta gttgataatg
    31261 ggtttgatcc ggccttattt gaaattgaga aaaaacaatt gctagcaagt ttagcagctg
    31321 atatggatga ttctttttat tttgcacata aagaattgga taaattgttt tttcatgatg
    31381 aacgtcttca attggaatat agtgatttac gaaatcgtat tttagctgaa actccacaaa
    31441 gttcttattc ttgtttccaa gaatttttag ccaatgatcg aatagatttc tttttcctag
    31501 gtgattttaa tgaggttgaa attcaaaatg tattagaatc atttggcttt aaaggtcgaa
    31561 aaggagatgt gaaggttcag tattgtcaac cttattctaa tatccttcag gaaggtatgg
    31621 ttcggaaaaa tgtgggacaa tccattttgg aattaggtta tcattactgt tctaaatatg
    31681 gtgatgagca acatttaccc atgattgtaa tgaatggttt acttggtgga tttgctcact
    31741 ctaagctctt tacaaatgtc cgtgaaaatg ctggattagc ttataccatt tcaagtgagc
    31801 ttgatttatt tagtggattc ttgaggatgt atgctggtat caatcgagaa aatcgtaacc
    31861 aggctcgtaa aatgatgaat aatcaactgc ttgatttaaa aaaaggttat tttacagagt
    31921 ttgagttaaa tcagaccaag gaaatgattc gttggtcgtt gttactttct caagataatc
    31981 aatcttcatt gattgaacgt gcttatcaaa atgccttatt tggaaaatct tcagcagact
    32041 ttaaaagttg gattgcaaag cttgaacaga ttgacaaaga tgctatttgt agagtagcta
    32101 ataatgtgaa actacaagcg atttacttta tggaaggaat agaatgacaa aggttgtttt
    32161 tgaagaaaaa tactatccag ctgtaaaaga aaaggtttat cgaactcgtt tggccaacgg
    32221 attgacagtt gctcttttgc ctaaaaagga atttaaagag gtttacggga gtgtaactgt
    32281 acagtttggt tcgatagata cgcttgtcac agaagttgac ggagatgtaa aacaatatcc
    32341 tggaggaatt gctcattttc ttgaacataa attatttgag agagaagatt ctagtgattt
    32401 gatgtcggct tttacgagtc taggtgcaga tagtaatgcc tttacaagct ttacaaaaac
    32461 aaactatctt ttttcagcaa cggattattt tttagaaaat ttatatttac ttgatgaatt
    32521 ggtaacatca gcacacttta ctgaagcttc cattctgaca gagcaggata ttattcagca
    32581 agaacgagaa atgtaccaag atgatccaga ttcgtgttta ttcttttcaa ctttagcgaa
    32641 tttgtatcct ggtacacctt tagcaactga tatagttgga agtgaggagt ccatttccca
    32701 aatcaatcta actaatttgc aagaaaattt tacaaagttt tacaaacctg taaacatgtc
    32761 tctgttttta gttggtaatt ttgatgtgga gcgagtacag gactattttg aaagcaaaga
    32821 actgaaagat tcagattttc aggaagtagc aagagaaaag ttgtttttac agcctgtaaa
    32881 gccaacagat agtatgagaa tggaagtatc ttctcccaaa ctagcgattg gagttagagg
    32941 taagcgagaa gtttctgaag cggattgcta tcgacatcat attttattaa aattattgtt
    33001 tgcaatgatg tttggttgga cttcggatcg ttttcaaaaa tgttatgaat caggtaaaat
    33061 tgatgcgtcc ttatctctgg aagttgaaat aacaagtcgc tttcattttg tcatgttgac
    33121 aatggatacg aaagagccag ttgctttgtc tcatcaattt aggaaggcta ttcgtaattt
    33181 tacaaaggat ttagatatta cagaggaaca tttagatatt atcaaaagag agatgtttgg
    33241 cgaatttttc agtagcatga actctcttga atttattgca acgcaatatg atgcttttga
    33301 aaatggtgag acaatttttg atttgccgaa aattttacag gaaattactt tagaggatgt
    33361 ccttgatgct ggacatcatt taatagatga tggtgacata gttgatttta caatattccc
    33421 atcgtagtaa cctattataa tagacactag aaagaaggga tgacaagtat gagaaaaaaa
    33481 acaattggag aggttttacg attagctaga atcaatcagg gattgagttt agatgaattg
    33541 cagaaaaaga cagaaatcca gttagatatg ttggaagcaa tggaagcaga cgatttcgat
    33601 caacttccaa gtccttttta cacgcgttct ttcttgaaaa aatatgcatg ggctgttgag
    33661 ttagatgacc aaattgtttt ggatgcttat gattctggga gtatgattac ttatgaggaa
    33721 gtagatgttg atgaagatga gttgacaggt cgtagacgtt caagtaagaa aaagaagaaa
    33781 aaaatatcat ttttaccttt attttatttt atcttttttg ctttatcgat tttaattttt
    33841 gtgacttatt atgtttggaa ctatattcaa actcaaccag aggagccttc tctttctaat
    33901 tacagtgtgg ttcaatcaac aagttcaact agctctgttc cccactcctc aagtagtagt
    33961 tcttctagta tagaatcagc tataagtgta tcaggcgaag gaaatcatgt agaaatcgct
    34021 tataagacaa gtaaggaaac agttaaattg caattggcag tttcagatgt tacaagttgg
    34081 gtcagtgttt cagaaagcga acttgagggc ggtgtaacct tatcgccaaa gaagaaaagt
    34141 gcagaagcaa cagttgcaac taaaagtcct gtaacaatta cgttaggtgt tgtaaaaggt
    34201 gttgatttga cagtagataa tcagactgtt gatttatcga aattaacagc tcagactgga
    34261 caaatcactg taacctttac taaaaattaa ggaaaaacga atgaaaaaag aacaaattcc
    34321 caatctctta acaataggtc gaattctctt tatacctatt tttatcttta ttttaacgat
    34381 aggaaattcg atagagagtc atatagttgc agctattatc tttgctgttg ccagtattac
    34441 cgactattta gatggatatt tagctcgtaa atggaatgtg gtcagtaatt ttggtaaatt
    34501 tgcagatcct atggcggata agttactagt tatgtcggct tttattatgt tgattgagtt
    34561 aggtatggct ccggcttgga ttgttgcagt gattatctgt cgtgagttag ctgtgacagg
    34621 tttaaggctt ttattggttg aaactggtgg aacaatttta gcagcagcaa tgcctggaaa
    34681 aattaaaact tttagtcaga tgtttgccat tattttcttg ctattacatt ggactttgct
    34741 tggtcaagtt ctactttatg tagccttatt tttcactatc tactctggct atgactattt
    34801 caagggtagt gcctatgtat ttaaagggac atttggttcg aaatgaaatc aataattgat
    34861 gtaaaaaatc tttcttttcg ctataaagaa aatcagaact actacgatgt gaaggatatt
    34921 acgtttcacg tgaaacgtgg agaatggctt tcgattgtag ggcataatgg tagtggtaaa
    34981 tcaacgacgg ttcgattaat tgatggctta ctggaagcag aatccggaga gattgtaatt
    35041 gatggccaac gtttgactga ggaaaatgtt tggaatatac gtcgtcaaat cggtatggtt
    35101 tttcaaaatc cagacaatca atttgttgga gcgactgttg aagatgatgt tgcttttggt
    35161 ttggaaaatc agggactttc tcgtcaagaa atgaaaaaga gagtggaaga agctctggct
    35221 ttagttggca tgttggactt taaaaagaga gagccagcgc gtctatcagg tggccaaaag
    35281 caacgtgtgg ccattgcagg tgttgtagcc ctaagaccag ctattttaat cttagatgaa
    35341 gcaacgagta tgttggatcc tgaggggcgt agagaactta ttgggacagt aaaaggaatt
    35401 cgaaaagact atgatatgac ggtcatttct attacccatg atttggaaga agtcgccatg
    35461 agtgatcgcg tattggtcat gaaaaaaggg gaaattgaat caactagtag tccaagggag
    35521 cttttctctc gaaatgattt agatcaaatt ggattagacg atccttttgc taatcaatta
    35581 aaaaaatctt tgagccagaa tggctatgat ttacctgaaa attatttgac agaaagtgag
    35641 ctagaggata agctatggga attgctctag aaaatgtgaa ttttacatat caagaaggta
    35701 ctcccttagc ttcagcagct ttgtcggatg tttctttgac gattgaagat ggctcttata
    35761 cagctttaat tgggcacaca ggtagtggta aatcaactat tttacaactc ttaaatggtt
    35821 tattggtgcc aagtcaaggg agtgtgaggg tttttgatac cttaatcacc tcgacttcta
    35881 aaaataaaga tattcgtcaa attagaaaac aggttggctt ggtatttcag tttgctgaaa
    35941 atcagatttt tgaagaaacg gttttgaagg acgttgcttt tggaccgcaa aattttggag
    36001 tttctgaaga agatgctgtg aagactgcgc gtgagaaact ggctctggtt ggaattgatg
    36061 aatcactttt tgatcgtagt ccgtttgagc tgtcaggggg acaaatgaga cgtgttgcca
    36121 ttgcaggcat acttgccatg gagccagcta tattagtctt agatgagcca acagctggtc
    36181 tagatcctct agggagaaaa gagttgatga ccctgttcaa aaaactccac cagtcaggga
    36241 tgaccatcgt cttggtaacg catttgatgg atgatgttgc tgaatatgcg aatcaagtct
    36301 atgtaatgga aaagggacgt ttagtaaagg ggggcaaacc aagtgatgtc tttcaagacg
    36361 ttgtttttat ggaagaagtt cagttgggag tacctaaaat tacggccttt tgtaaacgat
    36421 tggctgatag aggcgtgtca tttaaacgat taccgattaa gatagaggag ttcaaggagt
    36481 cgctaaatgg atagtatgat tttagggcgt tatatcccag gggattcgat tgttcaccga
    36541 ttggatccac gtagcaaatt gcttgctatg atgctactga ttttgattgt gttttgggct
    36601 aataacccct tgacgaatct gattcttttt atagcgacag ggatatttat tgccttgtca
    36661 ggagtatctc tttcattttt tattcagggc ttgaagtcta tgtttttctt gattgccttc
    36721 acaactattt ttcaactatt tttcatttct aatgggaatg ttttatttga gttttcgttt
    36781 gtgagaatca cggattatgc tttgcaacaa gctgggatta ttttttgtcg ctttgtattg
    36841 attattttct tttcaacttt gttaacctta acaaccatgc ctttaagttt ggcatcagct
    36901 gtcgaagctt tattagcacc tttaaagcgt gtgaaagttc cagttcatga aattggattg
    36961 atgctgtcta tgagtttgcg ttttgtccca accttgatgg atgatacgac tcggattatg
    37021 aatgcacaga aagctcgtgg agtggatttt ggagaaggaa gcatcgttca aaaagtaaag
    37081 gcgatgattc ccattttgat tcctcttttt gcgacaagtt taaaacgtgc agattccttg
    37141 gctatcgcta tggaagcgcg tggctatcag ggtggaaaag gcagaagtca ataccgacaa
    37201 ttgaaatgga ctctgaagga tacgctgacc attcttgtta ttctcgtact tggttgttgt
    37261 ttatttttct taaaatctta gtagctttca ggaattgata aaaagttact gtaacagttt
    37321 ttgatataaa ggtaggaata tgaaccgttt taaaaaatca aaatatgtca ttattgtttt
    37381 tgtcactgtt ctgcttgtgt cagctctctt agcgacgact tattcaagta caattgtgac
    37441 aaaattagga gatggaatct cattggttga tagagttgta caaaaacctt ttcagtggtt
    37501 tgattctgtc aaatcagatt tggctcattt gacacgaaca tataatgaaa atgaaagttt
    37561 gaagaaacag ctttaccaat tagaagttaa atcaaatgag gtggaaagtt taaagacaga
    37621 aaatgaacaa ctgcgccaat tgcttgatat gaagtctaaa ttgcaagcca caaagacttt
    37681 agcagcagat gttattatgc gttctccggt atcttggaag caggagttga ccttagatgc
    37741 aggtagatca aaaggtgctt ctgagaacat gttagctatt gcaaatggtg gcttgattgg
    37801 gagtgtttca aaagtagagg agaactctac tatagtcaac cttctgacaa atacggaaaa
    37861 tgctgataag atttctgtta aaattcaaca tggctctact acaatttatg gaattattat
    37921 tggctatgac aaggaaaatg acgttcttaa aattagccaa ttaaatagta atagcgatat
    37981 tagtgcggga gataaggtga ctactggtgg attaggaaac tttaacgttg ctgatattcc
    38041 tgttggtgaa gtggttgcca caacgcatag tacagactat ttgacacgag aagtaactgt
    38101 taaattgagt gcagatactc ataatgtaga tgtgatagaa ttagtgggga attcataatg
    38161 agacagttga agcgagttgg agtattttta ttgcttcctt tctttgttct aattgacgcc
    38221 catattagcc agcttctggg ctcatttttc ccccatgtac atttggctag tcattttctt
    38281 tttctatttc tcttatttga gacgatagaa gtatcagagt atctctacct agtctattgt
    38341 tttgttatag gcttggttta tgatgtttac tttttccatc taatagggat tacaactctc
    38401 ttatttatct tattgggagc cttccttcat aaattgaata gtgttatttt gttgaatcgt
    38461 tggacaagaa tgctagctat gattgtgctg acattcctgt ttgaaatggg tagttatctt
    38521 ttggctttta tggtagggtt gacagtagat agcatgtcga tttttatagt ctatagcttg
    38581 gtaccgacga tgattttaaa ttttttatgg attactgttt ttcaatttat ttttgaaaaa
    38641 tattatctat aagaacgaca tataaatgta acaaaggcgt aatatttatt aggccttttt
    38701 ttggtatact agtattgtct ttaaaagaag gagtatctac gtaatatgaa gaaaaaaatc
    38761 ttagcgtcac ttttattaag tacagtaatg gtttctcaag tagctgtttt aacaactgcg
    38821 catgcagaaa cgactgatga caaaattgct gctcaagata ataaaattag taacttaaca
    38881 gcacaacaac aagaagccca aaaacaagtt gaccaaattc aggagcaagt atcagctatt
    38941 caagctgagc agtctaactt gcaagctgaa aatgatagat tacaagcaga atctaagaaa
    39001 ctcgagggtg agattacaga actttctaaa aacattgttt ctcgtaacca atcgttggaa
    39061 aaacaagctc gtagtgctca aacaaatgga gccgtaacta gctatatcaa taccattgta
    39121 aactcaaaat caattacaga agctatttca cgtgttgctg caatgagtga aatcgtatct
    39181 gcaaacaaca aaatgttaga acaacaaaag gcagataaaa aagctatttc tgaaaaacaa
    39241 gtagcaaata atgatgctat caatactgta attgctaatc aacaaaaatt ggctgatgat
    39301 gctcaagcat tgactacgaa acaggcagaa ctaaaagctg ctgaattaag tcttgctgct
    39361 gagaaagcga cagctgaagg ggaaaaagca agtctattag agcaaaaagc agcagctgag
    39421 gcagaggctc gtgcagctgc ggtagcagaa gcagcttata aagaaaaacg agctagccaa
    39481 caacaatcag tacttgcttc agcaaacact aacttaacag ctcaagtgca agcagtatct
    39541 gaatctgcag cagcacctgt ccgtgcaaaa gttcgtccaa catacagtac aaacgcttca
    39601 agttatccaa ttggagaatg tacatgggga gtaaaaacat tggcaccttg ggctggagac
    39661 tactggggta atggagcaca gtgggctaca agtgcagcag cagcaggttt ccgtacaggt
    39721 tcaacacctc aagttggagc aattgcatgt tggaatgatg gtggatatgg tcacgtagcg
    39781 gttgttacag ctgttgaatc aacaacacgt atccaagtat cagaatcaaa ttatgcaggt
    39841 aatcgtacaa ttggaaatca ccgtggatgg ttcaatccaa caacaacttc tgaaggtttt
    39901 gttacatata tttatgcaga ttaatttaca gagggactcg aatagagccc tcttttcagg
    39961 ttttaccgtg acaatcccta ttaaaaatta tatcaaaata gcttgaaaat attggaaaag
    40021 tatggtagaa tgaaaattgt cgtgtgaacg ataatactca ttcttgatga attgtgaagc
    40081 agttgccctt gggtcgtttt gcgagttgaa gtcaagaaga ggaaaaaaac aaaaaggaga
    40141 aatactcatg gcagtaattt caatgaaaca acttcttgag gctggtgtac actttggtca
    40201 ccaaactcgt cgctggaatc ctaagatggc taagtacatc tttactgaac gtaacggaat
    40261 ccacgttatc gacttgcaac aaactgtaaa atacgctgac caagcatacg acttcatgcg
    40321 tgatgcagca gctaacgatg cagttgtatt gttcgttggt actaagaaac aagcagctga
    40381 tgcagttgct gaagaagcag tacgttcagg tcaatacttc atcaaccacc gttggttggg
    40441 tggaactctt acaaactggg gaacaatcca aaaacgtatc gctcgtttga aagaaattaa
    40501 acgtatggaa gaagatggaa ctttcgaagt tcttcctaag aaagaagttg cacttcttaa
    40561 caaacaacgt gcgcgtcttg aaaaattctt gggcggtatc gaagatatgc ctcgtatccc
    40621 agatgtgatg tacgtagttg acccacataa agagcaaatc gctgttaaag aagctaaaaa
    40681 attgggaatc ccagttgtag cgatggttga caccaatact gatccagatg atatcgatgt
    40741 aatcatccca gctaacgatg acgctatccg tgctgttaaa ttgatcacag ctaaattggc
    40801 tgacgctatt atcgaaggac gtcaaggtga ggatgcagta gcagttgaag cagaatttgc
    40861 agcttcagaa actcaagcag attcaattga agaaatcgtt gaagttgtag aaggcgacaa
    40921 cgcttaattt atacaaatag taattaccta ggagggcggg gcttagcccg gctctcctat
    40981 tttcaaaaaa tataggagaa ttaaaatggc agaaattaca gctaaacttg taaaagagtt
    41041 gcgtgaaaaa tctggtgccg gtgttatgga cgctaaaaaa gcgcttgtag aaacagacgg
    41101 tgacatcgaa aaagcgattg aattgcttcg tgaaaaaggt atggctaagg cagctaagaa
    41161 agctgaccgt gttgctgcag aaggtttgac tggtgtttat gttaacggta atgttgcagc
    41221 agttattgaa gtaaacgctg aaactgactt cgttgcaaaa aacgctcaat tcgttgaatt
    41281 ggtaaatact acagctaaag tcattgctga aggaaaacct gctaacaacg aagaagctct
    41341 tgctttgata atgccttcag gtgaaactct tgaagctgca tacgtatctg caacagcaac
    41401 tatcggagag aaaatctcat tccgtcgctt tgcattgatt gaaaaaacag acgcacaaca
    41461 ctttggagca taccaacata acggtggacg tatcggtgtt atttcagttg ttgaaggtgg
    41521 agacgaagca cttgctaaac aattgtcaat gcacatcgca gcgatgaaac caacagttct
    41581 ttcttacaaa gaattggatg agcaattcgt taaagatgag ttggcacaat tgaatcacgt
    41641 tatcgaccaa gacaacgaaa gccgtgcaat ggttaataaa ccagctcttc cacacttgaa
    41701 gtatggatca aaagctcaat taactgatga tgttattgct caagctgaag ctgacatcaa
    41761 agctgaattg gctgcagaag gtaaaccaga aaaaatctgg gacaaaatta ttccaggtaa
    41821 aatggatcgc ttcatgcttg ataacactaa agttgaccaa gcttacacac ttcttgcaca
    41881 agtttacatc atggatgaca gcaagacagt tgaagcatac cttgaatcag ttaacgcttc
    41941 ggtagttgag tttgctcgct ttgaagttgg tgaaggtatc gagaaagctg caaacgactt
    42001 cgaagctgaa gttgcagcta caatggcagc agccttgaat aactaataat agaaaggaag
    42061 caaattgctt ccttttttgt atagggctta gatttttcct gaaattgttt tttccccagc
    42121 ctcactcgat tagaataatt aaaacaaaaa gccctataat aagggctaag tgcatttagg
    42181 agactatact tcaaattcat agtaagcgcg tcataacaag gtatctatcc taattcccca
    42241 acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac tatgataatt
    42301 caactaagtg atttaggtca agttcacctt gtttgtgaca agacagatat gaggtaggga
    42361 atagactcat tagcctatgt agttaaaacc cactttgaat tggattcttt ctccggtcaa
    42421 gtctttctct tttgtggtga acgtaaagac cgctttaaag ccctttactg ggatggtcaa
    42481 ggattttggc tactatataa acgctttgag aacggaaaac tgacttggct aagtacagaa
    42541 aaggatgtca aagctctcgc acctgaacaa gtagattggc ttatgaaggg cttttctatc
    42601 actccaaaaa tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
    42661 agaaatcgat ttgattgtcc tgatcgattt gtcctgttct tatttcattt tactataaat
    42721 ccatcagaaa gttgtgattt ctattgaaat gaggactttc tttttacact catctgcttt
    42781 caaaaagcat tctagtccat ctccgattaa cgatggactt tatcacctcc ttctccagtc
//
LOCUS       DBERCW010000015        42640 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.015, whole genome shotgun sequence.
ACCESSION   DBERCW010000015 DBERCW010000000
VERSION     DBERCW010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42640
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.015"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            48..1295
                     /locus_tag="ACL72M_000991"
     CDS             48..1295
                     /locus_tag="ACL72M_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGS0716140.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            1373..2662
                     /gene="hisS"
                     /locus_tag="ACL72M_000992"
     CDS             1373..2662
                     /gene="hisS"
                     /locus_tag="ACL72M_000992"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGS0716141.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETISMAAYFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            2767..3231
                     /locus_tag="ACL72M_000993"
     CDS             2767..3231
                     /locus_tag="ACL72M_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716142.1"
                     /translation="MIDKVVRNLLLTFFLCKMTKIINFLTTILVKKKKMCYDVSKLRE
                     KKKGAMMWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLFQEMIGKE
                     PIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            3241..3447
                     /locus_tag="ACL72M_000994"
     CDS             3241..3447
                     /locus_tag="ACL72M_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0716143.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            3447..3644
                     /locus_tag="ACL72M_000995"
     CDS             3447..3644
                     /locus_tag="ACL72M_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716144.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNLYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            3647..4369
                     /locus_tag="ACL72M_000996"
     CDS             3647..4369
                     /locus_tag="ACL72M_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGS0716145.1"
                     /translation="MKKKRRLLFLMSIVLGMFVGMFKARVESHEIILDVKALMPWISA
                     ICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITG
                     VAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFAT
                     PKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFL
                     LVGAIHVYINVMQLPMVKRYFK"
     gene            4381..5022
                     /locus_tag="ACL72M_000997"
     CDS             4381..5022
                     /locus_tag="ACL72M_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0716146.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVAFAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            5040..5270
                     /locus_tag="ACL72M_000998"
     CDS             5040..5270
                     /locus_tag="ACL72M_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716147.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            5312..5548
                     /locus_tag="ACL72M_000999"
     CDS             5312..5548
                     /locus_tag="ACL72M_000999"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716148.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDKVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSNHTYGKATLTWFEEIFEEY"
     gene            5667..7430
                     /gene="aspS"
                     /locus_tag="ACL72M_001000"
     CDS             5667..7430
                     /gene="aspS"
                     /locus_tag="ACL72M_001000"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGS0716149.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            7408..8349
                     /locus_tag="ACL72M_001001"
     CDS             7408..8349
                     /locus_tag="ACL72M_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS0716150.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(8391..8588)
                     /locus_tag="ACL72M_001002"
     CDS             complement(8391..8588)
                     /locus_tag="ACL72M_001002"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716151.1"
                     /translation="MKIKVQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVADRTDEVS
                     SKHGFEVADRTDEVSNIYTAR"
     gene            complement(8730..9716)
                     /locus_tag="ACL72M_001003"
     CDS             complement(8730..9716)
                     /locus_tag="ACL72M_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0716152.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(9726..10526)
                     /locus_tag="ACL72M_001004"
     CDS             complement(9726..10526)
                     /locus_tag="ACL72M_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGS0716153.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(10779..11621)
                     /locus_tag="ACL72M_001005"
     CDS             complement(10779..11621)
                     /locus_tag="ACL72M_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGS0716154.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(11623..12915)
                     /locus_tag="ACL72M_001006"
     CDS             complement(11623..12915)
                     /locus_tag="ACL72M_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGS0716155.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(13026..14297)
                     /locus_tag="ACL72M_001007"
     CDS             complement(13026..14297)
                     /locus_tag="ACL72M_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0716156.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            14832..16364
                     /gene="malQ"
                     /locus_tag="ACL72M_001008"
                     /pseudo
     CDS             14832..16364
                     /gene="malQ"
                     /locus_tag="ACL72M_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            16390..18648
                     /locus_tag="ACL72M_001009"
     CDS             16390..18648
                     /locus_tag="ACL72M_001009"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HGS0716157.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(19692..20264)
                     /locus_tag="ACL72M_001010"
     CDS             complement(19692..20264)
                     /locus_tag="ACL72M_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716158.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            20341..20547
                     /locus_tag="ACL72M_001011"
     CDS             20341..20547
                     /locus_tag="ACL72M_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716159.1"
                     /translation="MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFSFRG
                     SVWGLVLALYHLLFIDKFVISNRK"
     gene            complement(20886..21734)
                     /locus_tag="ACL72M_001012"
     CDS             complement(20886..21734)
                     /locus_tag="ACL72M_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGS0716160.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            21886..22164
                     /locus_tag="ACL72M_001013"
     CDS             21886..22164
                     /locus_tag="ACL72M_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGS0716161.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22166..24229
                     /locus_tag="ACL72M_001014"
     CDS             22166..24229
                     /locus_tag="ACL72M_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS0716162.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLVRTKELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(24307..25563)
                     /gene="tyrS"
                     /locus_tag="ACL72M_001015"
     CDS             complement(24307..25563)
                     /gene="tyrS"
                     /locus_tag="ACL72M_001015"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGS0716163.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            25705..28170
                     /gene="pbp1b"
                     /locus_tag="ACL72M_001016"
     CDS             25705..28170
                     /gene="pbp1b"
                     /locus_tag="ACL72M_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGS0716164.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            28235..29146
                     /locus_tag="ACL72M_001017"
     CDS             28235..29146
                     /locus_tag="ACL72M_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0716165.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            29376..30074
                     /gene="dapD"
                     /locus_tag="ACL72M_001018"
     CDS             29376..30074
                     /gene="dapD"
                     /locus_tag="ACL72M_001018"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGS0716166.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            30142..31272
                     /locus_tag="ACL72M_001019"
     CDS             30142..31272
                     /locus_tag="ACL72M_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGS0716167.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            31284..31823
                     /locus_tag="ACL72M_001020"
     CDS             31284..31823
                     /locus_tag="ACL72M_001020"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGS0716168.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            31807..32484
                     /locus_tag="ACL72M_001021"
     CDS             31807..32484
                     /locus_tag="ACL72M_001021"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGS0716169.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(32556..33455)
                     /gene="galU"
                     /locus_tag="ACL72M_001022"
     CDS             complement(32556..33455)
                     /gene="galU"
                     /locus_tag="ACL72M_001022"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGS0716170.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(33477..34493)
                     /locus_tag="ACL72M_001023"
     CDS             complement(33477..34493)
                     /locus_tag="ACL72M_001023"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS0716171.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            34663..35145
                     /locus_tag="ACL72M_001024"
     CDS             34663..35145
                     /locus_tag="ACL72M_001024"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0716172.1"
                     /translation="MLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELS
                     IRQLIRIENGESRPTLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYE
                     DETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW
                     "
     gene            complement(35268..35690)
                     /locus_tag="ACL72M_001025"
                     /pseudo
     CDS             complement(35268..35690)
                     /locus_tag="ACL72M_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(35752..36402)
                     /gene="phoU"
                     /locus_tag="ACL72M_001026"
     CDS             complement(35752..36402)
                     /gene="phoU"
                     /locus_tag="ACL72M_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS0716173.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(36417..37169)
                     /gene="pstB"
                     /locus_tag="ACL72M_001027"
     CDS             complement(36417..37169)
                     /gene="pstB"
                     /locus_tag="ACL72M_001027"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0716174.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(37171..37986)
                     /gene="pstA"
                     /locus_tag="ACL72M_001028"
     CDS             complement(37171..37986)
                     /gene="pstA"
                     /locus_tag="ACL72M_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS0716175.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(37979..38842)
                     /gene="pstC"
                     /locus_tag="ACL72M_001029"
     CDS             complement(37979..38842)
                     /gene="pstC"
                     /locus_tag="ACL72M_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS0716176.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(38960..39835)
                     /locus_tag="ACL72M_001030"
     CDS             complement(38960..39835)
                     /locus_tag="ACL72M_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGS0716177.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(40002..41333)
                     /gene="pnpS"
                     /locus_tag="ACL72M_001031"
     CDS             complement(40002..41333)
                     /gene="pnpS"
                     /locus_tag="ACL72M_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGS0716178.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(41334..42041)
                     /locus_tag="ACL72M_001032"
     CDS             complement(41334..42041)
                     /locus_tag="ACL72M_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0716179.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(42125..42601)
                     /locus_tag="ACL72M_001033"
     CDS             complement(42125..42601)
                     /locus_tag="ACL72M_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGS0716180.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
BASE COUNT        12423 a         8072 c         9168 g        12977 t
ORIGIN      
        1 taaagctatt cttgatgtag aacttagaac aagaagggag attatctatg aaactattgt
       61 ttagaaatcc agcttataga attttgactt tatcacgctt cttcaatgct tttggtgctt
      121 cgattttcaa cctggtcttt atcgtctatg catcgacctt gtcacaagca tcttttgctg
      181 ttgctatggc gaatattgtc atgattcttc cgaccctctt tacagttttt gtagggattc
      241 gggcagatta cacgagggac aaggtcaaat ggatggtcta tagcggtttg tttcaggcgg
      301 ttctattttt cctagcagcc ctagttgttc agcaagctag tctctttgcc ttttctagcc
      361 tgtgtttgat caatgtcatt agtgatgtca tcagtgattt tgcaggtggc ttgcgcatgc
      421 ctcttattaa ggaaaaagta gctgaagatg atctgatgga ggcttattct ttttcacagt
      481 tcatcaccta tatttcagct attggtggtc aagctttcgg agtctggctc ttagctctat
      541 cggtcaacaa tttttctctc gttgcgggaa tcaatgcctg ctttttccta gtatcagcca
      601 ctatcctctt tttaggaaaa agcaaattga gcctgtcaat gtcatctgct gatggtgaaa
      661 acttaaaaaa tgagaagctt tctatcaaag accagttcct aacaatttac cgaaatttac
      721 gtctcgtttt tcttaaaagt gggcagaaaa actttggttt tatgctcttt gctgtcttgc
      781 ttattaattc cttgggtggc gctttgggtg gaatttataa tatcttcttt ttgagccatt
      841 ctctcttgaa tttttcttat acagaggcac tatttatcaa tcaattctgt gttttagtag
      901 caatcatcat cagtagcctt acgggcaatg attattttgg gaagcagtcc ttgcctagat
      961 tgatgatgtg ggcgaccgta ggacttagtc tagttggttt ggctaattta ttcaatcaag
     1021 tcgtgcttgg tttgctattt ctcttcttta ccctgtatgt gtctggtaaa gttcaaccaa
     1081 agattagtgc catgctcatg aaaaatctag ctccagaggt tctagctcgt actagtaatt
     1141 ttttaggtct attgtttacc ttatccatac ctgtgggaac agcttgtttt tcactagtag
     1201 ccgtatggaa tatacagttg acttggatgc tatttgttgg tctttccttg ctagctattt
     1261 ttttgacaat tcttaatctc aaaaatgata tctaaatcct aatttttttc ttactgtttt
     1321 aatcccttta tttgtggtaa aataagacta ttaagtttaa agaggattcc ctatgaaatt
     1381 acaaaaacca aaaggaacgc aggatatttt acctgctgaa tctgctaagt ggcagtacgt
     1441 tgagggcttt gcccgtgaga ttttcaagcg ctataactat gcagaagtgc gcacgcctat
     1501 ttttgagcat tacgaggtta tcagtcgctc tgtcggagat acaacggata tcgtaaccaa
     1561 ggaaatgtac gatttttatg acaagggtga ccgtcatatt accctccgtc cagaaggaac
     1621 tgcgcccgtt gtccgttcct atgtggaaaa taaactcttc gccccagaag tgcaaaagcc
     1681 aagcaagttc tactatatgg gacctatgtt ccgttatgag cgtccacagg cagggcgctt
     1741 gcgccaattc caccagattg gtgttgagtg ttttggctct agcaatccag ctaccgatgt
     1801 ggaaacaatc tctatggcag cctatttttt gaaggaaatc ggtattcaag gtgtcaaatt
     1861 gcacctcaac actcttggaa atcctgagag ccgtgcagcc taccgccaag ccttgattga
     1921 ctatttgaca ccgctcaagg agaccttgtc taaggatagc caacgtcgct tggaggaaaa
     1981 tcctcttcgt gtcttggact ctaaggaaaa agaagacaag gtggcagtag agaatgcgcc
     2041 gtctatcttg gactttcttg atgaagaaag ccaaactcat tttgatgctg tgcgtcagat
     2101 gttggaaaat cttggagtag attacatcat cgataccaat atggtgcgtg gtctggacta
     2161 ctacaaccac accattttcg agtttatcac agagattgag ggcaatgact tgacagtctg
     2221 tgcgggtggt cgctacgatg gtttggttgc ttactttgga ggccctgaaa ctgctggatt
     2281 tggttttggg cttggtgtag agcgcctgct tctcatcctt gaaaaacaag gcgtggccct
     2341 ccctatcgaa aacgccctag atgtctatat cgcagtcttg ggtgatggag caaatgtcaa
     2401 agccctagaa ctagtccaag ctcttcgcca acaaggtttc aaagcagagc gtgattacct
     2461 caaccgtaag ctcaaagctc agttcaagtc agcagatgtc tttgcggcta agaccctcat
     2521 caccctagga gagagcgaag tcgaaagcgg acaagtgacg gtcaagaaca accaaacccg
     2581 agaagaagtg caagtgtcac ttgagacaat cagccaaaac ttctcagaaa tctttgaaaa
     2641 actaggattt tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc
     2701 tcaaaacatg gttttgaggt tgtagatgaa gctgacgtgg tttgaagaga ttttagaaga
     2761 gtattaatga tagataaagt ggtcaggaac ttactcctga cctttttcct ttgcaaaatg
     2821 acaaaaatca taaacttttt gacaactata cttgtcaaaa agaaaaagat gtgttacgat
     2881 gtaagcaagt taagagaaaa gaagaaagga gctatgatgt gggtactagg atttatacta
     2941 tttatgattt tcttttattc taataattct aaaaaaatca agaaactaga gaataaaatc
     3001 aaaaaacttg agcgaaaaga gaaaggaaac gcagaaatgt cgagattatt tcaagaaatg
     3061 attggaaagg aaccaattat aacgggagtg tatattgggc cagataactg ggaagttgtg
     3121 gatgttgatg aggaatgggt aaagctacga cgtgtagata atacgggaaa agaaaaattc
     3181 aagttgcaac gcattgagga tatccaaacc gttgaatttg acggagagta ggtgtgtaac
     3241 atgcaactta aaaatcgtct aaaagagctt agagctcgcg atggtctcaa tcaaaccgac
     3301 ctagccaaac tggcaggggt ttccagacag accattagcc tactagaacg ggatgagtac
     3361 accccatcca ttatcattgc cctgaaaata tctcaaattt tcaacgaaac agtcgaatcg
     3421 gtatttcgtt tggaggagga cgagtgatga acaagtataa agtgatttat tatgtagtgg
     3481 tcatagcttt attagtcagt gtatttctac tgattgggat ggacctaagc tggtttaatc
     3541 tctatcaaag cgaccaattt gtttgggtct actttgctct catcccagta attgaatgga
     3601 ttgaaaagaa atccaaaaat ctagcaagtg aaaaaggaga atgaatatga aaaagaaacg
     3661 tagattgtta tttttgatgt ctattgtctt gggcatgttt gtagggatgt ttaaggcacg
     3721 tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg atgccatgga tatcagctat
     3781 ttgtttactg ataggtttca ttagtatgtt tttgactttc aatttcttaa agaaaagcag
     3841 aaaatttcat tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa cctattatgt
     3901 gcaaatgtat cggaatcttg agtttggaac cattgctttt aatattacag gtgtagcgat
     3961 tccattggct atttttattt cattaagtga ggtgattata ttgcatacaa accctcaaac
     4021 atttttcctt tctttcttac tctttgtggt attcttagtc gctcaaaaat ctctttttaa
     4081 aaccattgcg attgttcgtc agtttgattt ggaatttttc gctacaccaa aggatgtctt
     4141 gaactatata aattcttatg atgaagggga gcgtcaggct aatttggaac agagttttcg
     4201 aattttattc caattacacc aatatgtctt accagcctta tatatttttc ttattatcat
     4261 ttctttcttg acaggagaga ttcagttact agctttcttg cttgtaggag ccatccatgt
     4321 ttatatcaat gtgatgcagt tacctatggt aaaacgttat ttcaaataaa ggagttatct
     4381 atgaaattac ttaaaaacct tggctggatt cttctagccc ttctatcctt tttatttatc
     4441 tatggcttta ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc accctatgct
     4501 gttactctac tctatgtggc ctttgctgga gtatatgtgt acggcattta caaatggtat
     4561 cagaaggctc ctgttcatat tgagaagagc ggctttaatc gatttatttg gcttcctgtc
     4621 ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc ttcagtaaat
     4681 cagcaaatag cgacagactt gaccttgtct caaccacttt tctcattctt tgctgtggtt
     4741 atttttgctc ctttgacgga agagattgtt tttagaggga tgttagcacg ctatctcttt
     4801 cctaagcagg acaatagtaa acgaaccctg atttttcttc tggtatctag tcttctattt
     4861 gccttgattc attttccagg tgatgtgcaa caattttttg tctattttag ccttggtttt
     4921 agtttgggtt tggcttacat tagcagaaaa ggtctggtct acagtatttc tcttcacgct
     4981 ttgaataatt tagtcggctt tttgatgatt ctcatgctat aatagagtca ggaggtcaca
     5041 tgaaacgagt aattttatta gcagtgattc aggcagtcgt tctatttttc atcattggag
     5101 cgctagctta tgccttcaaa ggcgatttct tctataacta tctagcagtt gtctttgctc
     5161 ctattgcagg tgtactgcgt tttgggacgg cttacataac ggaaattgtc ttgcctcgaa
     5221 aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa aagagtccgg
     5281 tgaagttcat cggatttttg tattatactc aatgaaaatc aaagagcaaa ctaggaagct
     5341 agccgcaggt tgctcaaaac actgttttga ggttgtggat gaaactgaca aagtcagctc
     5401 aaaacatggt tttgaggttg tagatgaaac tgacgaagtc agctcaaaac atggttttga
     5461 ggttgtagat gaaactgacg aagtcagtaa ccatacctac ggtaaggcga cgctgacgtg
     5521 gtttgaagag attttcgaag agtattagcg ctaattttta gggctttcac ctgactttta
     5581 aagactggca aacttttctg atgattttca tgaagagcct gcgcttttat ggtaaaatag
     5641 taacagaata aaagaggaga gaaataatga aacgtagtat gtatgctggt cgtgttcgtg
     5701 aggaacacat cggacaagaa ataaccttga aaggatgggt tggccgtcgt cgtgaccttg
     5761 gtggtttgat ctttatcgat cttcgtgacc gtgaaggaat catgcagttg gttatcaacc
     5821 ctgaaaaagt atctgcagag gttatggcaa cagctgaaag ccttcgtagc gaatttgtta
     5881 ttgaggtgac tggtcaggtc gctgcgcgtg agcaagccaa tgataagttg ccaactggtg
     5941 cggttgagtt aaacgtgaca gctcttattg tgcttaacac agctaagaca acaccatttg
     6001 agattaagga tggcattgag gcaaatgacg atacacgttt gcgttaccgt taccttgacc
     6061 ttcgtcgtcc agaaatgttg gaaaatctta aacttcgtgc caaggtgacc cactctatcc
     6121 gcaactactt ggatgagttg gagtttatcg acgtggagac accattcctt tctaagtcaa
     6181 cgcctgaagg ggcgcgtgat tatttagtgc cgtctcgtgt taataagggg catttttacg
     6241 ctcttcctca aagtccacaa atcacgaaac agctcttgat gaatgctggt tttgaccgtt
     6301 actaccaaat cgttaaatgt ttccgtgacg aggacttgcg tggagaccgc cagcctgaat
     6361 ttactcaggt cgacttggaa acgtccttcc ttactgagca agaaatccaa gatattacag
     6421 aaggcttgat cgcgcgcgtg atgaaggaaa caaaaggcat cgaagtaacg ctaccgttcc
     6481 ctcgtatgaa atacgatgat gctatggctc tttacggttc tgacaagcca gatactcgtt
     6541 ttgacatgtt gcttcaggac ttgacagaag tggtcaaagg tgtagacttt aaagtctttt
     6601 cagaagcacc tgctgtaaaa gcgattgtgg tcaaaggagc tgcggacaac tattcacgta
     6661 aagacatcga caagatgacg gaagtagcca aacagtatgg tgccaaaggt cttgcttggg
     6721 tcaaggtggt tgatggagaa ttaaacggac cagttgccaa gttcttgact ggtatccaag
     6781 aagaattgac aacagcgctt gctcttgaag ataaggactt ggttctcttt gtggcggata
     6841 cgcttgaagt ggctaatgca acactgggtg cccttcgtgg acgtattgct aaagagcttg
     6901 gcttgattga taatgataag ttcaacttcc tttgggtggt tgactggccg atgtttgaat
     6961 ggtctgaaga agaaggccgc tacatgagcg cccaccatcc attcacactt ccacaggaag
     7021 agactgctca cgaattagaa ggtgatttgg ctaaggttcg tgccattgct tacgatatcg
     7081 tcttgaacgg ttatgagctt ggtggtggta gccttcgtat caaccaaaaa gaccttcaag
     7141 aacgcatgtt caaggctctt ggtttctcaa ctgaagaagc caatgaccag tttggtttcc
     7201 ttcttgaagc catggactat ggtttcccac cacacggtgg tttggctatc gggcttgacc
     7261 gttttgtcat gttgcttgct ggagaagaaa atatccgtga agtcattgcc tttcctaaga
     7321 acaacaaggc aactgaccca atgacacaag ctccatcaac agtcgctctc aaacaactag
     7381 aggaactcag cttacaagta gaagaagatg aaacaaacaa aacgaattaa gcggtggcgc
     7441 tattatctgc gccgctttgc ttatcagata aaaattttac gtgtcttaca aagtatctct
     7501 cgagaaaagt atgatgagaa gatttcggcc tctctggtct atggtttttt atcagcagta
     7561 gcagttaatt tctttttcca accagggcat gtgtattcga gtggtgcaac aggtctggca
     7621 cagattatct ctgccttgag taatcactgg tttggttttc atattccgat ttcgctaagc
     7681 ttctacgcca ttaacttccc tttgatggtc ttagcttggt atcagattgg ccataagttc
     7741 accgtcttta cctttatcac ggtatctatg agttccttct ttatccagtt tgtccctgtg
     7801 gcaaccttga cggaggatcc cattatcaat tccctttttg ggggtgttgt tatgggtttg
     7861 gggattggtt ttgctcttcg aaacaatatc tccagtggtg ggacggatat cgtcagcctg
     7921 actattcgca agaaaacggg taagaatgtc ggtagtattt ctttcttggt aaatggaact
     7981 atcatgctga tagcaggttt gacctttggt tggaaatacg ctctttattc tatgattacc
     8041 atctttgtct ctagccgtgt gacagacgca gtctttacta agcaaaagcg tatgcaggcc
     8101 atgattgtga caaatcatcc agagaaggta attgaaaaaa tccataaaaa attgcaccgc
     8161 ggagcaacca tgatccacga tgcagaagga acctataatc acgagagaaa ggcagtttta
     8221 atcactgtca ttacacgtgc agagtttaat gaatttaaac agattatgac acaagtggat
     8281 ccaagctcct ttgtctctgt ctcggaaaat gttcatattc taggaagatt tgttgagata
     8341 gataattagt gattaatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc
     8401 gtatatatgt tactgacttc gtcagttcta tctgcaacct caaaaccatg ttttgagctg
     8461 acttcgtcag ttctatctgc aacctcaaaa ccatgttttg agctgacttc gtcagttcta
     8521 tccacaacct caaaacagtg ttttgagcaa cctgcggcta gcttcctagt ttgcactttg
     8581 attttcattg agtataaaaa gatcttggga aaagactcaa tttcagtaga aaaggaagta
     8641 aatcttccca caataaaacg catagtatca agttttttca atacctgata gtatgcgttt
     8701 ttgcttttaa cgactctttg cccagtctct tatttttcga taattttgtg ggcgatcaat
     8761 tgacggtaac aaatttgttt attgttttta ttatcattaa taatctggag aatagtttca
     8821 agggaaacac gaccaagctc taaactattg atatcgacat aggctgccaa gttgagcttg
     8881 ggattaaccg agtcaaagct gagaacaggg acatccagct ggtgtttggc aatatagtta
     8941 caaacacctt cagctaggag gctatcggtt gtgatgatag catcaatttg tggatcgtgc
     9001 ttgaataatc gcttgctaaa tttatagccc ttttcttcca gaaactcgtc ggcaaagtag
     9061 atgcgattgt tgtcagtggt aagtttgtaa tgtttaagcg cctgttcata gcctgttaaa
     9121 cggtctttgg tcacgaagag ctttttactt cctccgataa aggcaatgcg tttgcagcct
     9181 tttttgatga aatattcagt cgcatcaaaa ccagcttgaa cattgtcgtt gtcgacaagt
     9241 gggatgaaag gagatagaga tttacctagg ataaggaagg ggaactgttc ttctgcgacg
     9301 agttttacga gagggtcttc ttcttgggca tagagaaaga ttagcccatc tacacgcttg
     9361 ccgtagacca tttgtgaaat agcgttgaga cgctccttct catctttccc tgttgctatc
     9421 tgaatggcat agtggttttc agatgcgact tgagagatgc cacgtagaac cgatggaaag
     9481 aaaggattct ggtagaaggc gtctgagtca tcaggaagaa ctaatccgat aacctgagta
     9541 tagctgctta ccaagctacg agcgttgagg tttgggtggt agttgagttc cttcatagcc
     9601 ttgcgaacgc gtttttttgt ttcgtcgcta atggttgatt tattttgaat aacacgggtt
     9661 acggttgaag gcgaaacacc agcagccttg gccacgtctt taatcgtaac gggcataaaa
     9721 atctcctatt tatggtaatt tggatcacgg aaatgtgttt tataaaagat agtgaccaga
     9781 tacagaacaa aaagaatatt ttgtacagta atcagggttg tcatattttg gccaaataat
     9841 cccaaaataa gtgtaatcag agtcggcaat cctaaacagt tcaagataaa gtgatagcac
     9901 tctttaaagg ttctaaatga aaagaggcgt gatttcttag tgatataaag gagaagacta
     9961 gctcctagag agacgataaa gaaattcaaa ccaaagagga agctcgcacc gagaactagg
    10021 aagaggctga tatagacacg attttgttgg taccagtctt tagaaattgc ttgggtcaag
    10081 ctgtctttgc ttttgaaact ctcagtctga atggctcggt aagagatgcg ggtcagttcc
    10141 ttgctttcct tgctgatgac tagctcattt gtatcgaaat gcagttgcaa gttcttaggt
    10201 aattccttga tttgacttgg accaatcaca acagaagagg cttgactaac tgttccagta
    10261 taagttaatg tgccatcgac aattgtagca tgttcagaga gatcctggac aacctcattt
    10321 gtcagaggtt catagacatt atcgataaaa gtttctagcg gataggtctc ctgggagctg
    10381 ttttggatag caatgggtac catagacaag ctgataagga agatactggt aaagagaagt
    10441 tgaaaccagt tgagcccgaa acgtttggac aggggcttac gaaaccccaa aatacttgaa
    10501 aaaaaggaaa atggatatgg aagcataggt atctttctaa aaggtgtttt ctatataagt
    10561 attattatat agagaaatgc gctttatttc aagtctagga gaaaaattgc ttgctacaag
    10621 gatattattt acagtgacaa ttgctaataa tcaatgaaaa tcaaagtgca aactagccac
    10681 aggttgctca aagcacaact ttgaggttgg agataaagct gacgtggttt gaagagattt
    10741 tcgaagagta taaaatgaaa aagggtggcg gggataaatt atcccttgtc gccaccactt
    10801 gtaagtcctg aaacaaagtt cttttgtagg aagaagaaga gaatacagat tggaagggcg
    10861 atgaggatag cacctgctga gaagtaggca atcttcaagt ttttcgcatt gttaacgaag
    10921 gtttggagac ctacggcaac agtaaagtat tctttctcac gaagcaagaa actagagagg
    10981 atgtagtccc cgaaaggtcc catgaaggcc cagagagctt gtacggcaac cattgggcga
    11041 acaagtggaa gaacaatttg ccagaagcgg cggaagtgtc ctgcaccgtc tagttttgca
    11101 gattcgtcta aagacattgg cactgtatcg aagtagcctt tcatgagcca agcattcatc
    11161 gggataccac caccaacgta gaggaagatg aggaaccagt tgtggttaag ggcgttcaac
    11221 ataagcgcca taacgaagaa ggctgtcaaa gcggccatag ttggcaccat ttggatgatc
    11281 aagaagaaga ccaaactttg tttacgagcc aagaagttgt aacggctgta agcataacca
    11341 gcaagtacga tgatacttgt ttgaacagcc atggtaatta aggcgataat caaagtgttg
    11401 aggtaccaag taccgtacaa ggtttcagtg aagaggcctt taaagttatc aaaattgagg
    11461 tcgatattag tatctagttt aaaggctgag acgttacctg ctttaaaggc tgacataatg
    11521 gtaatcaaca gtggatagat aattacaatt gatagaccaa tcaggtaaag gtaagtaagg
    11581 ctttgagtca gtctacgttt gagtttaatt gagttattca tcttagacgt cctccatatc
    11641 aaatgcgtgt agtttcttga atgcgatcat agagattgag atgacaatga tagagataat
    11701 caaggtaaca gctgccgcca ttgagtattg aggagatgta cctgttgtca aacggtagat
    11761 ccatgagatc aagatatcgg ttgaaccagc tccacctccg acactaccag gtcctccacc
    11821 attgaagagg tacatgatag agaagttgtt aaagttgaag gtgtattggc taatcaaagt
    11881 aggtgccgca acagccaaaa tcattgggaa agtgatgttg cggaattttt gccaagcgtt
    11941 ggcaccgtca atataagctg cttcgtaaag gtcgttagga atagattgca agatacccaa
    12001 ggtcagaacg tagatgtatg ggaatccgag ccaaccttgc atcataatca aggcaatctt
    12061 agtccaagtt gggtctgttt tccaaggaat aagagctcca tcaaggaaag gaaggaattt
    12121 agccaagatt ggcaatactt gagtgttgat agcaccgaca ctatcgttaa acatgtttga
    12181 gaatgtcaag atagtgatga aggctgggac agcccaagga agaaggaaaa taacaccaaa
    12241 gatacgtttt cctttgataa atggttggtt ggcaatgata gctgtgaaga taccaattac
    12301 gatttgtaaa gtagaagctg ccaaagccca aatgatagtc caagaaagaa cagaaccaaa
    12361 ggcagaacgg aaggtactca agctccaaat gtttgtaaag ttggtcaaac caacccagtc
    12421 caacaacttg tttggtggca agtgttggaa gtcgtagttg gtaaaggcga tcatcaaggt
    12481 tacgataact gggaagataa tcgcgaaggt catggcaaca taagatggaa tgatcaagag
    12541 gtaagggaag ccattttcat aaatcccttt gatcatgtct ttgagtgtgc gtggaactgg
    12601 aattccattg ttaatgcgtt ttgcaatcgt atgtgcatct ttgatatttg agaaataaaa
    12661 gagtacataa acgattacaa agattagatg gaaggcacca cgaatcagca taaagaggga
    12721 attatcacga cctggtttgt caccaagagt gatgaggttg ctcaattcag gggttgcaag
    12781 tgctaggaag taaaggacaa atacgatggt tacaccaagg aagataaaac ctttggcttt
    12841 ttgtttattg taaatctgtc ctaacccagg aatgatagac agcagggctg ctttactagg
    12901 ttgttgcttt tccatattaa ctcctttcat aggatactac ttttttataa gaaagctaaa
    12961 ttatttgtgt ctctattgat aaattcaaag ggggatttga tttccacccc ccttgaacaa
    13021 attttttatt caccaaattt ttgtttgatt gtttctttga tcaatgttac agcatcgtta
    13081 gcagctgttt tagcatcttt ttgaccactt acagcatcaa agagcatatt tttcgctgga
    13141 tcccaaactg cagacatttg agagatgttt ggcagtggtt gagtgttctt gaactgtttg
    13201 ataacagctg ttgtcaactc atcgttttta ccttcagcgt atgaacgagc ctcagtatta
    13261 gctgggattt cgttagtctt atcatataat actttttgtt gttcagttgc aacaaggaag
    13321 tctacaaatt tttgagaagc ttcaaggttc ttaacggctt gaggaatgac ccaagcttta
    13381 ccaccaccga atgcagcata ttcttttcca tttggaagag ttgggatagt tgcaactccg
    13441 tagtttactt tagcatcttt aaaggcttga gctttccaag gtccgtcgat gatagcagct
    13501 gttttacctt cttggaattg agtttggatt aagtttccag caccttctgt atcttgcata
    13561 cctttaggcc atttttcgta ccaagattta gcgtagttga tacctacgat agaaccgtcg
    13621 tttgcaagac cgatgtcttt agcgtcttta ccgttttggc caaagacgta agcaccgtta
    13681 ccggcaagaa gtccatatgt atagtagaag tttgtccagt cagctaggaa ggcagtagtt
    13741 ttaccatctt caccagcgaa tgcgtatttg ctatctttag caaggttttc caagtcagca
    13801 aatgtttttg gagcatcttt caccaagtct ttgttgtagt acataacaag tgactcgata
    13861 acggcaggag caccgtaaac tttaccatta gcagctgtta caagagattt agttgtgtcg
    13921 tctgttttag caccatcgct caatttcact tctgaaagtt gtccgtcaga accaaggcta
    13981 cctacacggt cgtatggagc catcataaca tcagggacat taccagattg gttgtcaaga
    14041 gaaagtttat caagacctcc tagagcatca ccagttttaa gagtgacttt tactccagct
    14101 tctttttcat aagctttagc aacctcttca atatagctct tatatccctc gtctacatat
    14161 acagtgagtt ctttgacttc agatgaacca gaatcagcag gcttatcagc agttttgctt
    14221 ccgcaagcta ccaaaagcaa gctagcaagt gtaacagttc caagcaccgc agtgctcttc
    14281 ataaatttag atgacatagt gtattcctcc caaagaatag caagttttat tgataaggaa
    14341 acgcaaacgt tttcctttat gagcttagta tagcacaaat agaaaacggt tgcaagtatt
    14401 ttttgtaaaa attttaaaaa atttttaagc ttgatttgat agcataattt tgcattttaa
    14461 tagaagaaaa gtatgaaata gataagaata cagtattttt aataaaaata tatggaatct
    14521 gtctaaagag ggaaaccagg aggggctacc tccctggttc taatccctat ctattttcta
    14581 tggacgtttg tgctttgtta catataaatt caagctccct aaggaggttt tgtactttgt
    14641 agactgtctc gtgagagtca aaccttagga ttagatagtt ttaagttatc tttgctaaaa
    14701 tgagttagtc tccttaaaaa taatcaaaaa agttttttaa aaacgcttgc aattatgctt
    14761 gaaaaggagt atacttataa gtaacgcaaa cgtttgcgtc tgcaaaatac gcaacgttcc
    14821 attattttaa cacacgaggt gctattatga aaaaacgtca aagtggtgtg ttgatgcaca
    14881 tctcttctct tccaggagct tacggaatcg gatcatttgg tcaaagtgct tacgacttcg
    14941 ttgatttctt ggtccgtaca aaacaacgtt actggcaaat ccttccatta ggagcaacta
    15001 gttacgggga ttctccttac caatctttct cagccttcgc aggaaacact cattttatcg
    15061 atttagatat cttggtggag caaggtttgt tggaagcaag tgaccttgaa ggagttgact
    15121 ttggtagcga tgcgtctgaa gttgactatg ctaaaatcta ctatgcacgt cgtcctcttt
    15181 tagaaaaagc ggtgaaacgt ttctttgaag tcggagatgt taaagatttt gagaaatttg
    15241 ctcaagacaa ccaatcatgg cttgagctct ttgctgagta tatggctatc aaagagtatt
    15301 ttgacaatct tgcttggact gaatggccag atgcagatgc tcgtgctcgt aaagcttcag
    15361 cacttgaaag ctatcgtgag caattggcag acaagttggt ttaccaccgt gtgactcaat
    15421 acttcttctt ccaacaatgg ttgaaattga aagcttacgc taacgacaac cacatcgaaa
    15481 tcgttgggga catgccaatc tacgtagcgg aagattcaag tgatatgtgg gcaaatccac
    15541 atctcttcaa aacagatgtc aatggtaagg ctacttgtat cgcaggatgc ccaccagatg
    15601 agttttctgt aactggtcag ctttggggta acccaatcta tgactgggaa gcaatggaca
    15661 aagacggcta caaatggtgg attgaacgct tgcgtgaaag cttcaaaatc tacgatatcg
    15721 ttcgtatcga ccacttccgt ggcttcgaat cttactggga aatccctgct ggttccgata
    15781 cagcagcacc tggtgagtgg gtgaaaggtc caggctacaa gctttttgca gccgttaagg
    15841 aagaacttgg tgagctaaac atcatcgcag aagaccttgg cttcatgaca gatgaagtga
    15901 tcgaattgcg tgaacgtact ggcttcccag gaatgaagat tcttcaattt gccttcaacc
    15961 cagaagacga aagcattgat agcccacact tggcacctgc taactcagtt atgtacacag
    16021 gaacacacga taacaatacg gttcttggtt ggtaccgtaa tgagattgat gatgcgactc
    16081 gtgagtacat ggctcgttac acgaaccgta aagaatacga aacagtggta cacgctatgc
    16141 ttcgtacagt attttcatca gttagcttta tggcaattgc aactatgcaa gatttactag
    16201 aattggatga ggcagctcgt atgaacttcc catctaccct tggtggaaac tggtcttggc
    16261 gtatgactga agatcaattg acaccagctg tcgaggaagg tttgcttgac ttgacaacaa
    16321 tttatcgccg aattaatgaa aatttggtag atttaaagaa ataagacaat aatcaggaga
    16381 caactaaaca tgttatcact acaagaattt gtacaaaatc gttacaataa aaccattgca
    16441 gaatgtagca atgaagagct ttaccttgct cttcttaact acagcaagct tgcaagcagc
    16501 caaaaaccag tcaacactgg taagaaaaaa gtttactaca tctcagctga gttcttgatt
    16561 ggtaaactct tgtcaaacaa cttgattaac cttggtcttt acgacgatgt taaaaaagaa
    16621 cttgcagctg caggtaaaga cttgatcgaa gttgaagaag ttgaattgga accatctctt
    16681 ggtaatggtg gtttgggacg tttggctgcc tgctttatcg actcaattgc tactcttggt
    16741 ttgaatggtg acggtgttgg tcttaactac cactttggtc ttttccaaca agttcttaaa
    16801 aacaaccaac aagaaacaat tccaaatgca tggttgacag agcaaaactg gttggttcgc
    16861 tcaagccgta gctaccaagt accatttgca gactttactt tgacatcaac tctttacgat
    16921 attgatgtta ctggttatga aacagcgact aaaaaccgct tgcgtttgtt tgacttggat
    16981 tcagttgatt cttctattat taaagatggt atcaactttg acaagacaga tatcgctcgc
    17041 aacttaactc tcttccttta cccagatgat agtgaccgtc aaggtgaatt gctccgtatc
    17101 ttccaacaat acttcatggt ttcaaacggt gcgcaattga tcatcgacga agcaatcgaa
    17161 aaaggaagca acttgcatga ccttgctgac tacgcagttg tccaaatcaa cgatactcac
    17221 ccatcaatgg tgattcctga attgattcgt cttttgactg cacgtggtat cgatcttgac
    17281 gaagcaatct caattgttcg tagcatgact gcctacacta accacacaat ccttgctgaa
    17341 gcgcttgaaa aatggcctct tgaattcttg caagaagtgg ttcctcactt ggtaccaatc
    17401 atcgaagaat tggaccgtcg tgtgaaggca gagtacaaag atccagctgt tcaaatcatc
    17461 gatgagagcg gacgtgttca catggctcac atggatatcc actacggata cagtgttaac
    17521 ggggttgcag cactccatac tgaaatcttg aaaaattctg agttgaaagc cttctacgac
    17581 ctttacccag aaaagttcaa caacaaaaca aacggtatca ctttccgtcg ttggcttatg
    17641 catgctaacc caagattgtc tcactacttg gatgagattc ttggagatgg ttggcaccat
    17701 gaagcagatg agcttgaaaa actgttgtct tatgaagaca aagcagctgt caaagaaaaa
    17761 ttggaaagca tcaaggctca caacaaacgt aaattggctc gtcacttgaa agaacaccaa
    17821 ggtgtggaaa tcaatccaaa ttctatcttt gatatccaaa tcaaacgtct tcacgagtac
    17881 aaacgccaac aaatgaacgc tttgtacgtg atccacaaat accttgacat caaagctggt
    17941 aacatccctg ctcgtccaat cacaatcttc tttggtggta aagcagctcc agcctacaca
    18001 atcgctcaag acattatcca tttaatcctt tgcatgtcag aagttattgc taacgatcca
    18061 gcagtagctc cacacttgca agtagttatg gttgaaaact acaacgttac tgcagcaagt
    18121 ttccttatcc cagcatgtga tatctcagaa caaatttcac ttgcttctaa agaagcttca
    18181 ggtactggta acatgaaatt catgttgaac ggagctttga cacttggtac tatggacggt
    18241 gctaacgtgg aaatcgctga gttggttgga gaagaaaaca tctacatctt cggtgaagat
    18301 tcagaaactg ttatcgacct ttacgcaaaa gcagcttaca aatcaagcga attctacgct
    18361 cgtgaagcta tcaaaccatt ggttgacttc atcgttagtg atgcagttct tgcagctgga
    18421 aacaaagagc gcttggaacg tctttacaat gaattgatca acaaagactg gttcatgact
    18481 cttcttgact tggaagacta catcaaagtc aaagagcaaa tgcttgctga ctacgaagac
    18541 cgtgacgcat ggttggataa agtcatcgtt aacatttcta aagcaggatt cttctcatct
    18601 gaccgtacaa tcgctcagta taatgaagac atctggcact tgaactaata ctcttcgaaa
    18661 atctcttcaa accacgtcag ctttatctgc aacctcaaag cggtgctttg agcaacctgc
    18721 ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaaa tttatactaa
    18781 tacattttgt aaaaaagcga gtttcgattg aaattcgctt ttttaaatgc tgtggatttg
    18841 ggtcaatctt gtctaaaaat agggaaatcc tagatacagt gaaggcttta aatgctggtt
    18901 tttactgtct tcagccttat attttttcgt agttggttac ctcatatctc ttgtattcgc
    18961 ttacataaag tattataata taattgtagg aaagaaggtg tttttatgat atacacactt
    19021 aaattggtgt tgtttattac ctttcttgta ataagcttgt tacctgataa gatttttgga
    19081 aaaaataaaa aaatttggaa aatagttttt gcaatattga cggcagtggc agcattgtca
    19141 tttatgtact aagttatttt aagaatgtag ggaaataaac cctacatttt tttagttttt
    19201 tctgttttct aaattctatt tatccaagag cttcaacatt tcttgcttct tcgcttcaag
    19261 ttctgcacgc ttttcttcga tttcggcatg ttttttctcg agttcagaac aacttgcatc
    19321 attgctaaat tcttttcgcc atcaggagat agggtgagtc tacatgtcta ttactcaccc
    19381 aaagcagtcc tacaaagcag gaattttctg ttactttttt ggaaatagta acgtttatac
    19441 agctttgaca cttcgtatca aagcgccaaa cacactccga gggatttaca gaaagcagaa
    19501 aaggaatgat ctggtataag atcattcctt ttctctcttt ttctttaagt aattatatac
    19561 aatgtacgac gaagtcgtca ttgcaatgct gatccaccac ctaaagggaa ctttaaacaa
    19621 cattgataag ataaagaata taaacaacga aaatacgtta tacccaatta attttattgt
    19681 atatctcatg attaaaagtt aatccttccg ttgttaggaa tggcatcatt tttatcccat
    19741 aattgtgcta aataagtccc cggtgataat aaattcatag cgaattctaa agcaacatca
    19801 tttacaaacc aactacctag atatctagaa attgctgaac gaatagcact ttttgctgca
    19861 tgttttcctt ttactttaat tagatttgca aggcctgcag tagttcctcc taatgctaaa
    19921 gctattgcag tatctaatag agcacccatt tgattaactg taataccttg ccaagctgct
    19981 ctaaatggag agtatgtagg tgggattgta taatcgcctt gtaattgtcg gttaattact
    20041 tctttgatcc attgttgtga gacgtctgga tgaaaagatt ggatttcgtt tgcaagtgta
    20101 ttgatttgtt cttctgttag agaagtgaca ggttgaagtt ccatatttgt ttcaatttgt
    20161 gatacttgtt cagaagcgta tacagctgaa acacttggaa tcgctgatac aattaacaca
    20221 attgacgtca aaaaaaccga aataaatttc attaatttgt tcatgagctt ttctcctttt
    20281 tatttgtatc tgcttacatt ttatcatata ctgttattat agtcaaaaaa atatgctatt
    20341 atgttaaaaa aatatttttc aaaatataaa tggacggatt tattttggat tttatttgtt
    20401 attttgacct gcctctatat tggtaaccat gatttgttta ctctcaatca tcaagaattc
    20461 tcttttcgtg gtagcgtttg gggtctggta ctggccttat atcacttatt gttcattgat
    20521 aagtttgtaa tttcgaatcg aaaataaaga ttagaactat gattgactgg ctacttttaa
    20581 tattgatttt ggaggaagat tttgtctcta ttatttatta ttttaaattt atctattttg
    20641 tacaagattt attctttgag acgggagaaa tcgaaatact tgatttatac ggcctatatc
    20701 atatttgggg taaatgtagt atatggtatt caatggttat taagagaact gatttcaact
    20761 atttcccctt aatgtgtatg gaaactataa caaaacgcat aagattaagg tttgtgtacc
    20821 tgttcttatg cgtttttata atattgaaga ttttcggtaa gttttatacc tttgggaagt
    20881 ctagtttaga atgctttccc aaccaaaatc tctgcttcga tggtaatctc tgtcagttgg
    20941 ctccagtcaa tcttgctctg gtcaacgtga aagaggagag gagtcatact gagtagggct
    21001 tggagttgtt ctgctgtgat agtcttagtc agagaggcag tttgactaga taggatggta
    21061 aagtgttcct ggaaatgctc cttgatatct tggttagaat actccttgtt tgtcagctgg
    21121 tcctgtactc tttgacggat ttctttgagg tgattttcag ttgggataac ctttatcaag
    21181 ataccgtctt tggataaaac gcgacgaaat tctccatagt tggcaggtga gaagatatca
    21241 agcagaatat ccatgttagc gtcttttata ggaagtcgtg ccaagtcgcc aacaaaccaa
    21301 ttgactgccc agttgggttc acttttagca gcgatttgga ctgaatcttt ggagatgtca
    21361 aaggcataga aagttttttc agagtgactt tcttgtagtt tgcgagaata gaatccttca
    21421 ccacaaccga tatccaaaat tgttgtggta gtttttgagc ttgcaagcaa gtcagataca
    21481 gcatctaaga tagcttggta aaagccggct tctaggattt gttgacggtt ttgaaaattt
    21541 tccttgttat agttagcaga ttgcttgatt tgaggtgcta gattgacata gccaaatttc
    21601 gccaagtcaa aagaatgacg gttgcagcac ttgaaattag tctctaacag agtcagattt
    21661 tcttgacaga taggacaggc aaaggcagtc gcagaagcaa aacgctgaag tttgggcttg
    21721 agatttgtat tcatagttta agtgtatcaa aagaggcaaa tgaaagcaac tttaggaata
    21781 agtagatggg agattcagta gaaataaaac taattctcca atttatagaa tgaaattgct
    21841 tttatatcta aattgctata taataatgat aaggaggaaa taagtatgtt aaaagaagta
    21901 ttaaccgttg caaaagttgc gaaaaaatct tcattatttt tgggtggtgt cgcatttggt
    21961 acccttggtt tgaaaatctt agcaagtaag gaagctaaaa aaggttattc taaagctttg
    22021 gctaaggctt acaagttgaa agacgagcta gatgcatctg tttctgttgt gaagcaacat
    22081 ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc aagagaaaaa agaagagcaa
    22141 ttagatagcc ttataggtga ataatatgtc ttttaaagtg ctacatagag gataccaaca
    22201 tatccgacta tcatcttctt tttcacttac cttggatatt caagactatc ttcgttcctt
    22261 ggcgagagat gaaaagggga ttgagtctat ccagttttac atggatcaac agcactttac
    22321 tctacgcata aaagaaggct tttctgtatt agataatgca gaagcctttt taaaaagaat
    22381 tgataaaggg aaagtttctg agttgatgac tcttcccatt cgtagagaag agagtgctta
    22441 ttctattgtt tcaggtgcag cggttaagcg tgtacttttt cgtagttttg tgccgtatcc
    22501 tattcgctat atatggactt gttatcaggc tttgggttat attagagaag cctatcaaac
    22561 actagcgcgt aaggaactaa cgatggaagt cttggactgt tcggctattt tattgtcttt
    22621 gtttatgaac caatccaaga cagctagcaa tatcatgttt atgcttgatt tggggaatca
    22681 tttagatcag tggtccttga aaaaaactgc aacagattta gaacagagtc ttcttgcaaa
    22741 agagagcgat gtattcctag tacagggcga tacggttgtt agtatcaaga gttccgatgt
    22801 tcaaatagga gatgtcttga tcttatctca aggaaatgaa attctgtttg atggacaagt
    22861 agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca ggagagagtt ttccagttga
    22921 aaaaagagag tctgatttgg tttgtgcaaa tacagtatta gaaactggag agttacgcat
    22981 tcgtgtaaca gataatcaga tgaacagccg tattttacag ctgattgagt tgatgaagaa
    23041 atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc aagatggcgg ataaagtcgt
    23101 caaatataat ttcttggggg ctgggctgac ttacctattg acaggttctt tttctaaggc
    23161 tatttctttc ctattggtcg atttctcctg cgctttgaaa atctctactc ctgtagctta
    23221 tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg attaaggatg gagatgttct
    23281 ggagaaatat ctggaagttg atactttctt gtttgataag acaggaacaa tcacaactag
    23341 ttatcctata gttgaaaagg tgttaccttt tggagactat agtgaggaag atattctcag
    23401 aatcagtgcc tgtcttgagg aacacattta tcatcctatt gctaatgcca tcgtcaagca
    23461 agctgagata gagggaattg aacatgagga aatgcatggg aaactccaat atatcgcaag
    23521 caaggggatc aaatctcata tagatggcca accagttctt attgggaatt atgtcttgat
    23581 gcaggatgag cagattcata tcagttcaga acaaaatgct ttaattgaag agtacaagag
    23641 tcactacaat ctcttattct tggcttatca aaatgaattg attggaatgt tctgcattca
    23701 tactcctttg agaaaagaag caaaaacagc cttggataaa cttaaggcac aggggaaaaa
    23761 attgattctg gcaacagggg acaccttggt taggacaaag gaattagtca aagatttgcc
    23821 ctttgatcag gtctatacag acttgaaacc tgatgggaaa tttgagttag tagagaaact
    23881 gcagaaagca ggtcacacta ttttgatggt tggagatgga ttgaatgact cagcggcttt
    23941 aactctatca gatatcggtg tggtgatgaa tgagagtgca gatatttcta agcagatgag
    24001 tgatatctta ttgttagata atcgtttgga tttcttccaa gagttggatt cgttatcatc
    24061 atctttgcaa acactcatca agaaaaatat tcaagatacc gttgtcgtaa atagtagttt
    24121 gattggcttc ggcttattta attggctcag tccttcaaat ctctctatct tacataatct
    24181 aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa aatagataga tgagagttat
    24241 taacagcaaa aaggagttac ctttctcgag gttaactcct ttgtttatag ataaatgttg
    24301 aatagtttag taagtcaata caaagtattt tttcttccca cgacggataa cagtcagttc
    24361 attctctaac ttatcagcgt cactcaagac atagtcaagc tcttggatgc ggtcgccgtt
    24421 tacgtagatg gctccgtttt ggacgtcttc acgggcttgg cgttttgagt taactatacc
    24481 agatgagacg agcagttcca cgatattgtt gttttcgtct gcctgtactt ggtagtttgg
    24541 cacaccacga agtccttgtt tgagctcttt gacagaaagg tttttgatgt ttcctgcaaa
    24601 gagttgctca gtgatgttaa gtgcttcttt gtaggcttct tctccgtgaa caagtgtaac
    24661 aacttcacga gccaagactt tttgagccaa gcgttcgtgt ggcgctgctt caaattgttt
    24721 acgaatatct tcaatctcat caagtgacaa gaaagtaaag attttcaaga agcgaacagc
    24781 gtcagcgtcc atcacgttca tccagaattg gtacatttcg tatggagaag tcttttcggg
    24841 attgagccag acggcatttc cttctgattt accaaatttc ttaccagttg catctgtgat
    24901 tagtggaaca gtgataacgt gaccagtctt gtccgcctta cgacgaagca attcggtacc
    24961 agctgtcata tttccccact ggtcagaacc accgatttga agagtgacat tatggtcttg
    25021 gttaaggacg aagaagtcat acccttgcat gatttggtaa gcgaactcag tgtaagaaat
    25081 tcctgtttcg atccgttttt taacagattc cttactcatc atgtagttga ccgtgaagta
    25141 ttttccaata tcacggagga agtcaatgaa gctgatgctg ccaaaccagt cgtagttgtt
    25201 gaccatgaca gccttgtttt cgccattttc aaagtcaaga aaacgagaaa gttgtccttg
    25261 gatagacttg acccagccat ctactgtgtc ttttgtttgg agactacgtt cagcatcttt
    25321 gaaggacgga tctccgatga gacctgtagc accgccaacg agcgcataag gtttgtgacc
    25381 tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg tggcctaggt gaaggctgtc
    25441 agcagttgga tcgtagccag tataataaga aacttgacct tcttctaggg ctttacgcaa
    25501 agcttcttca tcagtcgttt gaaatatcaa accacgctct tttagctcat caaaaatgtg
    25561 catgtgtttt ttctcctttt taaaattatt gtttctacct attgtatcac aaacttgggc
    25621 aatagcctag cagaataggg aagaaagtgg ctattttatt gaaaatttcc cttttgtggt
    25681 ataatagata aagtgaggaa atccatgcaa aatcaattaa atgaattaaa acgaaaaatg
    25741 ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag ctagacctgg caagaaaggt
    25801 tcaagtacca aaaaatctaa aaccttagat aagtcagcca ttttcccagc tattttactg
    25861 agtataaaag ccttatttaa cttactcttt gtactcggtt ttctaggagg aatgttggga
    25921 gctgggattg ctttggggta cggagtggcc ttatttgaca aggttcgggt gcctcagaca
    25981 gaagaattgg tgaatcaggt caaggacatc tcttctattt cagagattac ctattcggac
    26041 gggacggtga ttgcttccat agagagtgat ttgttgcgca cttctatctc atctgagcaa
    26101 atttcggaaa atctgaagaa ggctatcatt gcgacagaag atgaacactt taaagaacat
    26161 aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg ggaaatttgt aggtttgggt
    26221 tcctctagtg ggggttcaac cttgacccag caactaatta aacagcaggt ggttggggat
    26281 gcgccgacct tggctcgtaa ggcggcagag attgtggatg ctcttgcctt ggaacgcgcc
    26341 atgaataaag atgagatttt aacgacctat ctcaatgtgg ctccctttgg ccgaaataat
    26401 aagggacaga atattgcagg ggctcggcaa gcagctgagg gaattttcgg tgtagatgcc
    26461 agtcagttga ctgttcctca agcagcattt ttagcaggac ttccacagag tcccattact
    26521 tactctcctt atgaaaatac tggggagttg aagagtgatg aagacctaga aattggctta
    26581 agacgggcta aggcagttct ttacagtatg tatcgtacag gtgcattaag caaagacgag
    26641 tattctcagt acaaggatta tgaccttaaa caggactttt taccatcggg cacggttaca
    26701 ggaatttcac gagactattt atactttaca actttggcag aagctcaaga acgtatgtat
    26761 gactatctag ctcagagaga caatgtctcc gctaaggagt tgaaaaatga ggcaactcag
    26821 aagttttatc gagatttggc agccaaggaa attgaaaatg gtggttataa gattactact
    26881 accatagatc agaaaattca ttctgccatg caaagtgcgg ttgctgatta tggctatctt
    26941 ttagacgatg gaacaggtcg tgtagaagta gggaatgtct tgatggacaa ccaaacaggt
    27001 gctattctag gctttgtagg tggtcgtaat tatcaagaaa atcaaaataa tcatgccttt
    27061 gataccaaac gttcgccagc ttctactacc aagcccttgc tggcctacgg tattgctatt
    27121 gaccagggct tgatgggaag tgaaacgatt ctatctaact atccaacaaa ctttgctaat
    27181 ggcaatccga ttatgtatgc taatagcaag ggaacaggaa tgatgacctt gggagaagct
    27241 ctgaactatt catggaatat ccctgcttac tggacctatc gtatgctccg tgaaaagggt
    27301 gttgatgtca agggttatat ggaaaagatg ggttacgaga ttcctgagta cggtattgag
    27361 agcttgccaa tgggtggtgg tattgaagtc acagttgccc agcataccaa tggctatcag
    27421 accttagcta ataatggagt ttatcatcag aagcatgtga tttcaaagat tgaagcagca
    27481 gatggtagag tggtgtatga gtatcaggat aaaccggttc aagtctattc aaaagctact
    27541 gcgacgatta tgcagggatt gctacgagaa gttctatcct ctcgtgtgac aacaaccttc
    27601 aagtctaacc tgacttcttt aaatcctact ctggctaatg cagattggat tgggaagact
    27661 ggtacaacca accaagacga aaatatgtgg ctcatgcttt cgacacctag attaacccta
    27721 ggtggctgga ttgggcatga tgataatcat tcattgtcac gtagagcagg ttattctaat
    27781 aactctaatt acatggctca tctggtaaat gcgattcagc aagcttcccc aagcatttgg
    27841 gggaacgagc gctttgcttt agatcctagt gtagtgaaat cggaagtctt gaaatcaaca
    27901 ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagagg tagaagtcac aggttcgact
    27961 gttaccagct attgggctaa taagtcagga gcgccagcga caagttatcg ctttgctatt
    28021 ggcggaagtg atgcggatta tcagaatgct tggtctagta ttgtggggag tctaccaact
    28081 ccatccagct ccagcagttc aagtagtagt tctagcgata gcagtaactc aagtactaca
    28141 cgaccttctt cttcaagggc gagacgataa ttctctaaat gaagtggcca atcaatggat
    28201 tgccactttt ttcttttcgt gttacaataa gggtatgaat cagtatcaga aaaagattgt
    28261 taacggaaaa atttattcgc tcctatccgg cttaatatgg ggaatctgtg gaattttagg
    28321 agagtacttc tttactcatt atcaggtgtc ttcgggctgg attacctcta tgcgtttgac
    28381 actggcaggg agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc aagtgctaga
    28441 tatttggcga gacaagaaaa attacctgcc ctttttagcc tatgctattt tggggatttt
    28501 ttcagttcag tattttttct atctctgtgt agaatactca aatgctacga cagcaactat
    28561 tttacagttt attagccctg tctttatcct cttttacaat cgcttggttt atcaaaaacg
    28621 agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg ctgggtgttt gcttgatggc
    28681 gacaaaggga gacctctctc agttatccat gacgccgcta gctcttataa caggtttgct
    28741 gagtgccatg ggtgttatgt ttaatgttat cttgccccaa ccttttgcta agcgttatgg
    28801 ttttgttcct acggttgggt gggggatgat tttggcaggt ttgtttagca atgtcctctc
    28861 gccggtttat cagctttcct ttactcttga tatttggagt atcttgattt gcctcattat
    28921 cgctttcttt ggaacggctt ttgctttttt catttccatg aaggctgtgt ccttggtttc
    28981 tcctttggtg gttgccgtta tcagtgccag tgaacctctc tcttctgctc tcttgagtgt
    29041 tttgttctta ggattagtag tggattggtc cctccttcta gctatagcct tgattatttt
    29101 acccatgata tttttgtcta tagaagaagc gaaagaaagt agataaaaag tcttttctta
    29161 attctaaaag tgtgctatac tagaatagtc aataaaacac ggggagatag ttgtgaagag
    29221 tgtttttagg ttgtatcggt aggggcttgc ttttaccgac agcacgtttt atctcacatc
    29281 cctaaaaaat catacctaaa aacagacaaa aaggtttcaa atttgaggcc ttttttggta
    29341 gaataggtat cattataacg aaccaggagg cacctatgac tgctacaaaa atgaacgctc
    29401 aagaaattat ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa gtaacctttg
    29461 aggggcaact cgcaactgct gtgcctagct ctgttgtcaa actaggaaat gtcctattcg
    29521 gagactggaa ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa gattatgttg
    29581 tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga taagcgtgct atcaacgctc
    29641 gtatcgagcc aggtgctatt atccgtgacc aggtggaaat tggtgacaat gctgttatca
    29701 tgatgggagc tgttatcaat atcggtgctg aaatcggtgc tggaaccatg attgacatgg
    29761 gtgccatcct tggtggccgt gccatcgttg gaaaaaatag ccacgttggt gcaggtgcag
    29821 ttttggcagg tgtgattgag ccagctagtg ctgaaccagt ccgtgtcgga gacaatgttc
    29881 tcatcggggc taatgcagtg gttatcgaag gagtccaaat cggtagtggt tcagttgtcg
    29941 cagcaggagc tattgttacc caagatgtcc cagaaaacgt ggtagtagca ggtgttccag
    30001 ctcgtattat caaagaaatt gatgcccaaa ctcaacaaaa aacagcgcta gaggatgcgc
    30061 ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca gcctctttct
    30121 gctatatcgg aggacagata gatgttagat ttgattcaga ctagacgaga tttacaccag
    30181 attccagaga ttggcttgga ggagttcaag actcaggctt atttgctgga tgtgattgag
    30241 aaattgacta cgggcaagga ttttgttcaa attcgtactt ggcggacagg gattttggtc
    30301 tacctgcagg gaagtcagcc ggagcgaacc attggttggc ggacagatat tgatggcctg
    30361 cctatcgtcg aacaaacagg tctacctttt gcttctcaac accaaggtcg catgcatgcc
    30421 tgtggccatg attttcatat gaccattgcc ttaggctgtc ttgagcgcgc ccttgaggag
    30481 caacccaaga ataatctgct ctttctattt cagcctgctg aagaaaatga agctggtggt
    30541 atgctcatgt atgaggacga tgcttttgga gattggttgc cagatcaatt ttatggcctc
    30601 catgtccgtc cagatttgaa agtcggccag attgcgacta atactcatac actctttgca
    30661 ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc ttttcctcat
    30721 gaagccaatg acgccttggt ggcggctagt tactttgtga cccaagtgca gtcagttgtt
    30781 agccgcaatg tcaacccaat cgagggagca gtggtgacct tcggcgtttt tcaagctgga
    30841 accaccaaca atgtcatcac agacacagct tttttacatg gaactattcg tgccttgaca
    30901 caggacatga gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagg ggttgcagct
    30961 gcctttgata tggaagtcga agtggaactc aaacaaggtg gatacctacc tgttgagaac
    31021 aatccagcct tggcgcgtga actgatggac ttctttgacg aaaaagacgg aatcgagttg
    31081 attgatatcg aacctgctat gacaggcgag gactttggtt atctcctttc aaaggttgat
    31141 ggcgtgatgt tttggctagg tatcgatagt ccctacgctc ttcatcaccc tcaaatgagt
    31201 cctaaggaag aagtcttagc tattggggtg gctgcggtgt ctagtttcct gaaaaagaag
    31261 gcagcagaat agagggcttg tctatgaaat cggaattacg caagcaagtc ttgcatgaaa
    31321 tgaaggctat atctcaagag caaaaacagg ctatagacca agctttaacc gagcgaattt
    31381 tacaacaccc cttttatcaa gaagccaagg tcatcgcaac ctacctctct ttttctcatg
    31441 agtttcaaac gcgggaactg attgagcagg cgctgaagga cggcaagaag gttttaatac
    31501 ccaaaactta tcccaagggg cgcatggact ttgtagtcta tgatccgcag cagttggtaa
    31561 aaactgcctt tgccttactg gagccacagg gagatttgga agtggtggat gcatctcaga
    31621 ttgatttgat tcatgttcct ggcctggctt ttacgacgga tggatatcgg attggatatg
    31681 gtggaggtta ttatgaccgc tatctggaac atttttctgg tcatactttg agtacggttc
    31741 atccttgtca aattcaggac tttatacctg aaaaccatga tattcctgtt caggaggtat
    31801 taattgatga aggaaatctt tgatagacgt taccctgtga cgagtttctt cctcttagtg
    31861 acggccttgg tatttttact aatgttggtc actgcaggcg gaaactttga cagggcagat
    31921 acattatttc gatttggagc catgtatggg ccagctattc gcctctttcc cgagcaggtt
    31981 tggcgtctct tgtctgccat ttttgttcat attgggtggg aacatttcat tgttaatatg
    32041 ctttcacttt attatcttgg aaggcaggta gaggagattt tcggttctaa gcagtttttc
    32101 tttctctatc ttttatcagg aatgatgggc aatctctttg tttttgtatt tagtcctaaa
    32161 tccttagcag caggcgcctc tacctctctt tatgggctat ttgccgcgat tattgttctt
    32221 cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc aatcctatct gacacttttt
    32281 gtggttaaca ttattggaag tgttctgatt ccaggaatca gcctagcagg ccatatcggt
    32341 ggtgcagttg gtggcgcatt tctagcagtt atctttccag ttagaggaga aaaacggatg
    32401 tataacacca gccagagatt aggagcggta gtcttgttcg taggactcgc cattttgctt
    32461 ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa tttgtgtaat gaaaaaagat
    32521 aaggcatttt ttgaacctta tctttttatt ttattttatt ccttctcagt caattctttt
    32581 ccaagttgga tgaggtaatt cttcaaatca tctttgactt gtgggtgttt gagggcgtag
    32641 tcgatggatg ttttcatgaa gccaaacttg tctccgacat cgtaacgagc cccattgaac
    32701 tcacgagcaa atacacgttg tgttttattg agggtgtcga ttgcatctgt cagctgaatt
    32761 tcatttcctg cacctggagc ttggttttcg aggatttgga aaatttcagg cgtgaggagg
    32821 tagcgtccga taatagcaag gtcgctagga gcgtcctctg gagctggttt ttcaacaaag
    32881 gtttcaacac tgtaaagacc atcttttcct tcgccttgcg gagcaataac cccgtaagca
    32941 gatacttcgt catgagggac tggcatgaca gcgatagtag acgcgtgggt acgctcgtag
    33001 tcatccatga gttgtttggt aagtggaaca gccttttcgt ctgtgatatc catcaagtca
    33061 tcaccaagca taacgacaaa aggttcattt ccgacgaaag ccttggcttg caaaacagca
    33121 tctccgagac cgcgtggatg agtttggcgg ataaaatgca gccgcatgtc agttgtttta
    33181 tcaactagct tcaaaagatc tgttttccct ttttctttga ggttatattc caattcgaag
    33241 tttgaatcga agtggtcctc aatagaacgt tttgatttac cagtgacaac tagaatatct
    33301 tcaatacctg atttgagagc ctcttccacg ataaactgga tagttggttt gtctacgatt
    33361 ggcaacattt ctttggcaag ggccttggtt gctggtaaaa atcgagttcc tagtccagca
    33421 gcagggataa ctgcctttct aacttttgat gtcataaaaa tcctttctat agagggttaa
    33481 gaccactcat tttctgcttt aaattcattg ttcatgatgt cataaatggc atctttgata
    33541 ttggttccgt gataaataac ttggtaaata gcctgtgtaa tgggcatata gactccaagt
    33601 tcttgggcta gttcataggc tgctcgagtc gttgaaattc cttcgattac catgcccata
    33661 ttagcttcta tatcagctag ggattctcct cgtccgagag catctccagc tctccagtta
    33721 cgagagtgga tggaagttcc cgttacgatc aaatctccca caccagataa gccgctatag
    33781 gtcaatggac tggccccgag tgctacccct aggcgggtga tttctgctaa acctcgagcg
    33841 atgatggctg ccttagcatt atcaccaaat ccaagaccat gtaaagctcc agcaccgaca
    33901 gcaataatat ttttaagagc accagcagtt tcaaccccga taacatccgt attggtataa
    33961 agtcggaagt agtgattact aaatagctcc tgaacgtatt gagctgtttg taaatcttta
    34021 gaagcagcag ttattaaagt taggtcacgc acaatggtct cttctgcatg actaggccct
    34081 gaaacaacga cgatatcact acggagatgt tcaggaattt cttcttcaag aatggttgat
    34141 aatcgtttat ggctatcagg ttctaatccc tttgatgcgt gcatgatgat aaccttatgg
    34201 tccaaggttt gtgcaacttg ctgggcaaca agtcgtgtca cttttgttgg gacaacaaac
    34261 aaaatcgcat ccacattttt caatgtttct gctaagtcgg tgtaggcaat gatattttcg
    34321 tctagaacga catctttaaa gtagtgctta ttagtatggt gtgtattaat ttcattgatt
    34381 tgctcgggaa gatttcccca aatacgtacc tcgtgtccat tgtcatttaa gacttgtgaa
    34441 agggcggttc cccaagaacc aggccccaag acggcgacgg tttgtttttc catgatttcc
    34501 tccttgatag atttctttct cttattctat catattctag gggattttgc acttgcatta
    34561 ctggggtatg gtggaaaaat acacaaagac cgagatgaag ggataaactc ttagtcttta
    34621 gttaaagtga gaagaaatct gatagatagt ttgattcagt atatgcttat aatagaggta
    34681 aacaactcag gaagttcttg taggttgcga gagtttggcg aaaaaattaa aagattacgt
    34741 ttggctaaaa aaatcagtcg ttcagaattt tgtggtgatg agtctgaatt aagtatccgt
    34801 caattaatta gaattgaaaa tggagaatcc agaccaacac taacaaagtt aaaatatatt
    34861 gctgaacgtt tggaggttga agattacaag ttgatgccaa gttatataga gttggataag
    34921 gaatacctag aattgaagta tttcttgatg aggactccta catacgaaga tgaaactatc
    34981 gcccaaaaga aagagagtgt ttttgataag atttttgaag agtattatga taggctacct
    35041 gaggaagaaa gatttatcat cccaaattat tcatatctag cactagcgaa ctacacagtt
    35101 caaaaattac cagaaaagct agttgaaata ctgtccttct ggtgattttg cttaatttct
    35161 gatgttcgag acatgattga ggagatttgt cttgattttt tcctaaaaaa gggcagactc
    35221 ctcccttggt ttgatgctcg atttttaaaa taaggtgact tattctgtta ggcagttttc
    35281 ccctgccctc tagctctata tggaacaggg agtatcagat ttatctggca gattgtatca
    35341 aataaggctt gaaactgttt tgaataggcg tatagacttg agaatttgag aatatgtcgt
    35401 ctagcagtag agacatattt tccggcaata tgaaggaaga gacgtcgaaa acgcttgata
    35461 gtcaaggcct ttacttcatc accagctagc tgctttaaaa agaggtagag attataagcc
    35521 agacagccca tcatcatacg tacttcattc ttaatcatgg tcgaactatc tgtcttatcc
    35581 ccaaagaatc ctgctttcct ttctttgata aagttttcag cattccctcg ttcacgatag
    35641 aattgaaaca gctcctcact atctacactg cttaaattgg tcaaatgaac ttttttacaa
    35701 ccataaaaaa gagcacttaa tcgtactctt ctcttttaag gattagttga attaattcaa
    35761 atccactagt tctcctgttt ctaggtagac taggcgttca caaatgttag caatgtaatc
    35821 agcgaagcgt tccagatgcc ctatgatata aaggtattga gttccattgg gaattgaggt
    35881 ttcttggtct ttcataagtc caatgatttc ctttgataag gcataataat attggtcaat
    35941 ctgttcatct ttttgagcaa tactaatagc ttttgaggct tggtgcaaag gaaaggcaac
    36001 caataaatcg gctagcatgc tgagggataa tttacccatt tggtgtaact gttcttcgtc
    36061 aggggctagt tgattttctt ttagttgcaa aacagctttg gcaatgcctg ccatatggtc
    36121 tcccatacgt tcaaggtctg aacaagaaga catgatgcta atcacaaatc gaaggtcaga
    36181 cacttgtggc tgctgcaagg ccaacaaacg ggcacaggtc aattcgatag cgctttgacc
    36241 ttggtttata gcatgatcct tattgataat tagctctgcc atctccttgt ctttggaggc
    36301 taaggccagt aaggcttttg aagctgtttc aaggacaagt tgccctagtc ctaaaaagga
    36361 ttgttctaat tcatgcaatt ctaagtcaaa ttgatttctc ataggttttt ccttccttat
    36421 ccgaaccgtc ctgaaatata gtcttctgtg cgctgatctt ttggattggt aaacacgtca
    36481 acggtatctc caaattcgca aatttctcct gttaagaaaa aagcagtttt atctgaaata
    36541 cgtgaagctt gttgcatgtt atgggtaaca atgataatcg tataatcctt ttttagttgc
    36601 tgaatgaggt cttcaatttt taaagtggag atagggtcta aggctgaagt cggctcatcc
    36661 attaacagaa tatcaggttc tactgctaaa gctcgcgcaa tgcaaaggcg ttgctgctga
    36721 ccgccagata aggacatggc actcttttta agatcatctt tgacttcttc ccaaatggct
    36781 gcccctttta aagatttctc cactaaggca tctaattgtt ttttgtctcg aataccatgt
    36841 gtccttgggc cataagccac gttatcatag atagacatgg caaagggatt aggctgttga
    36901 aaaaccatcc ctacacgctt acgtagctga ttaaggttga atttgctact ataaatatct
    36961 tgctcatcta agaggacttg gccttcaata tggcaagaag gaaccaaatc gttcatccgg
    37021 ttaagggttt ttagaaaagt tgatttgcca caaccagatg ggcctatcaa ggcagtaatc
    37081 tgtctttctg gtaattgaat cgaaatattt tttaaggctt gaaaatcccc gtaaaataag
    37141 tctaggtgtc tgactgaaaa tgttcccata ctaggaagct cctttcacaa gttttcgaga
    37201 taataagctt gatagagtat ttatcattaa aacagtaata atcaaaatca caccggtagc
    37261 ataggcttca ttgacatgta gcccctcact tgacagcata tacatatgca gggctagaga
    37321 acgacctgaa gacatgagac tacttggcgt attggtagag gtacctaatg tatacatgag
    37381 ggcagctgtc tcaccaacga tacggccaat agctagtatc actccagcta aaatacctgg
    37441 catggcaact ggtagaacaa ttctaaaaac agtccgtaac ttacctgccc caagtccata
    37501 acttgcttga cgcatgctat cactaacaga taaaagggct tcttctgttg agcgaataat
    37561 gactggcaac accatgatga ctgaggttaa gattcctgat aacagagagt attgaaaacc
    37621 taagaagact acaaagaaga gcatgccaaa cagaccaaaa acaatggaag gaatcccaga
    37681 caaggtatct gaggccaatc gcatgatttt aacacaaagg gaatcttttt ttgtatattc
    37741 cacaagataa aaaccagcaa aaatccctat gggcaaggct aaaagaagag caccaaagac
    37801 cagaataacg gtggaaataa tcgctggcat aagggaaatg ttctcagaag tataagtcca
    37861 agaaaagagg gatagactta gatgaggtaa acctttgatg aggataaaac caatgattaa
    37921 aaagagagag ccaaaggtta aagctgaaaa acaataaacg agaagtttta gcaggtattt
    37981 actcataaga tgattttcct ttcaagtagg caaagtaggc attaatcaag agaataagga
    38041 aaaagagaac tgctgaggtt gcaataaggg cttccctatg ctgacctgat gcgtaagcca
    38101 tttccagaac aatattggtt gttaaggttc tggttcctga aaagagtcca cttggaataa
    38161 tcggctggtt gcctgccacc aaaataactg ccatggtttc acctactgcg cgaccgatgc
    38221 ctaaaataac tgctgataaa ataccagatc tcgcagctgg caagatgaca ctaaaaatac
    38281 tccgttcatg actagctcct agagccaagc taccagaata atacgttttg ggaactgttc
    38341 ggatagcaga ttctgacaaa ctgataatgg ttggcaaaat cattattcct aatagtaacg
    38401 aagcggttag gacactcatg ccatttccta aaaagcttct aatccaaggc accaataatt
    38461 gtaggccgaa aaaaccataa acaatagatg gaatggccgc catcaagttg atagctgatt
    38521 ttaagaagcc atagacgggc tttggacaat aataaaccat aaacaccgat gtcaagatgc
    38581 ctgttggcac cccaatcaca atcgctccta aggtaattaa taaggaacca acgatcattg
    38641 gtaaaatacc atagcttgcc ggaatgttcg ttggcgacca atcactgcct aataaaaaac
    38701 gggcaaagcc gtagttagcc atgaaaggta agccattact aaaaataaag aaacagatta
    38761 gcaaaatagc tacaacagct actgttgcac tcatgaaaaa aattgcccta aaaactgctt
    38821 ctttgaaggc ttgttttatc acatcttgtc ctttctagtg aagaaagtaa gggagatacg
    38881 acacctccct acttgccttc tttatcttat tgtacgatga aacgtctgca tctctttaga
    38941 gatttatgga gcaaacattt tatttaatct tgtcccaggt ggttaatttg ccactaaaaa
    39001 cgtctgcaag ttcagccata ctgacttggc ttgccttatt gtcattattg accacaacag
    39061 caataccgtc taaagcaata gcatcatggg tgagactctt accttcttca ggagttaatt
    39121 ccctagaaac cataccaata tcagcggttt tctccttaac agcggtaata cctgctgaag
    39181 acccattaga ggtaatatca atcgtaactt ctggattttc ttttttataa gcttctgcta
    39241 atttttccat taaagaagat actgaagtgg aacctacaac agacaacttg cctgataagt
    39301 gttggcttgt atattctgtg gtttcagttt tagcttcaat aaatttatta tctgtgacca
    39361 cttgttgacc ttgtttggag tggataaagc tgataaaatc ttgacctagc ttggaaagat
    39421 tagaagacca aacaatgttg aagggacgtt gaagagggta ttcaccatct aaaactgtgt
    39481 ctcgactagc cttgacacca tcaatctcta aagccttgac agatttcgtt aaagatccca
    39541 aggagatgta gccgatagca ttagcattcc cttgaactgc tgagagaaca ccttctgtac
    39601 tattttgaat cacagctgtt ttggcagtgt tgtcaatttt tttatcaccg tcttttttga
    39661 gaatccctgt gatttctgtg aaggcacccc gtgttccaga gccattttct cgtgaaatca
    39721 cctcaatcgt tcctgaagct gactgtttgg aagcagctga ctgattgcca caggcaacaa
    39781 gcccaaatcc tgataagcca atggctgcaa gagtaagcat ttttttgaat ttcataataa
    39841 tcacctttat ctctatgtat ttttcttgtg taggcttact acatttatag tctaacaagt
    39901 ctttgtaaag gtttatccct gattcatgta aagattgtgt aaagaatcaa aaaaagccac
    39961 ttttgaaaaa tggctgctcc taaaaatagc tttaaaaatt attagtcctg tgcgaaagat
    40021 tggttaggaa gaaaaatcgt gaagcaactg cctctgccaa gctgactcgt caccgtgact
    40081 tggccaccta ataattgact gagttctttg acaatggcaa ggccaagacc agtgccacca
    40141 gtttgtctgc ttcgaccttt attaactcgg taaaaacgtt caaaaatacg atcctgctct
    40201 aattgactaa taccaatccc tgtatctgat acagaaatct taatgccttc gttcaccttt
    40261 tgggtcttga cctcaatttt tcccccttgt tcagtgtaac ggatggcatt ggataaaaga
    40321 ttgagtaaga tttgggaaag taattgacta tctgatacga gggtgacatc atctggcacc
    40381 tgcaccttta gctgtaaatc cttcttcttg agctgaggtt gcaagctttg agtcaaatcc
    40441 tgtacaaatt cagccaaaga aagggtcgtc cattgtatag gcatttgttg agccttagat
    40501 aaggtaagaa gatgctcaac aatatgctca agacgcaaac tttctttgta aataatgtct
    40561 agaaagtcat ccttgagcgc ttcttcttca gctgacatcc ccttaatggt ttcagcaaag
    40621 cccttaattg aagtaactgg tgtcctcaat tcatgggagg catttgagac aaaggctaaa
    40681 tttaactttt cataagttct aatcgttgtt aaatcatata gcaagacgag cacagcttcc
    40741 acagattggg tggggctaaa aacgggaact gctgtcactt ctaaaatcaa gtcaccctca
    40801 tgaaacccac ttacttcttg ttttaacctt gttttttgat caaaggcttg gtgaactaaa
    40861 ttccgaatat ccatccgttt gaggtcatca agtgaactta tgtcgccgtc cacatcggga
    40921 aaataatgag gcagagagcg actggataat aacatctgac cttgagcgga aactaaaaac
    40981 gtccccatgg ttaggtgcga cagaagaacc tccattgttt cggctaggtc cttgtattgc
    41041 tgatcctgtt gggagacttt ggtttttagg ccagacacat actgagccaa agactttaag
    41101 tcttcttgcc ctttttctaa aaagtattca ctactggtca agagaggttg gtgcaaggtc
    41161 tcaaaagcaa cttcccattt ccaaaggcaa aagagccagt agccaccttg tcccaaagaa
    41221 agggctagaa gaaagagacc gatgccttta ctgatccaag ttaatgccat ccctgcaatc
    41281 agaatgaggc taacacttag attgactagc caaaattgaa ggtagcgttt catctataac
    41341 tccttgaact tataaccata accccgaatg gttcgaataa attgaggggc tttaggattg
    41401 tcttcaattt tttccctcaa cttaccaata tgaacgtcca ccaaacgtgt ttcctgccca
    41461 aagtcatacc cccagatacg ttccaaaaga cgctctctag tcagtgtcat gttgggatgt
    41521 ttcataagat agagcaagag ttcaaattct tttggggtca aactcagtaa cttattcgcc
    41581 ttgtagactt catgacgctc agggtatact ttcaaggtcc caaatagcca agaatcgtca
    41641 gcgatattat ctgaatcatc tccttcttgt tctcctttag ttcgcctgag gacagccttg
    41701 acacgcgcca gcaattctct agggctaaaa ggcttggtca ggtagtcatc agcccctaat
    41761 tccaaggcca aaaccttatc aaattcatca cttttcgcag aaaccatcat aattggagtt
    41821 ttgacgcctt tggctctcag ccgcttacaa acttccatgc catctaattg tggtaacatg
    41881 atatcaagca agataaaatc aaagggttct gtttctgcca aagctaaggc cttccgtcca
    41941 tttgttacca attgagtaga aaagccttcc ttacttaaat ggtagtcaag caatttcaga
    42001 atgtgttctt catcatccac taataagact tgttttgtca tctattatct cctattggta
    42061 acattataac acaattatca gaaatcctaa cattgctaaa tcagattaaa tttgcttatc
    42121 aagactagta tctggtcaaa cgctcaatca tctccttgtg ctctggatag gtcgccagta
    42181 gatctaccct ttcaaataat tcaaaatcct caaattcaaa accaggagca acaagacaag
    42241 aaaccagagc ataatcctta tcaactgttg atccccaaat agtgccctta ggaacacagt
    42301 agtgaagttg ttgccctttg gatatgtcca ggcctaaagt gactgcttcg tagtgaccat
    42361 ctgctgtaat catgtgaaca gtaagtgggg atcctgcatg aaaataccag atttcatctg
    42421 ctgtcaatcg gtgaaaatgt gaaggattcg tttcttctaa taagaaataa atactggtat
    42481 aaagcgccct tcccttacca gcaaggttta tagtgtctga agcttttttt gtttgtctaa
    42541 aatagccacc ttcaacatgg ggagctaact ctagagttct tatcaagtct tctttatcca
    42601 tcggggccaa tgggttgaag taactcttgt tcaaagtggt
//
LOCUS       DBERCW010000016        40273 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.016, whole genome shotgun sequence.
ACCESSION   DBERCW010000016 DBERCW010000000
VERSION     DBERCW010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40273
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.016"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            5..75
                     /locus_tag="ACL72M_001034"
     tRNA            5..75
                     /locus_tag="ACL72M_001034"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="ACL72M_001035"
     tRNA            110..183
                     /locus_tag="ACL72M_001035"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="ACL72M_001036"
     tRNA            266..355
                     /locus_tag="ACL72M_001036"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="ACL72M_001037"
     tRNA            366..439
                     /locus_tag="ACL72M_001037"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="ACL72M_001038"
     tRNA            443..515
                     /locus_tag="ACL72M_001038"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="ACL72M_001039"
     tRNA            528..608
                     /locus_tag="ACL72M_001039"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="ACL72M_001040"
     tRNA            613..683
                     /locus_tag="ACL72M_001040"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="ACL72M_001041"
     tRNA            698..770
                     /locus_tag="ACL72M_001041"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            784..855
                     /locus_tag="ACL72M_001042"
     tRNA            784..855
                     /locus_tag="ACL72M_001042"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:816..818,aa:Gln,seq:ttg)
     gene            865..948
                     /locus_tag="ACL72M_001043"
     tRNA            865..948
                     /locus_tag="ACL72M_001043"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:899..901,aa:Leu,seq:caa)
     gene            1055..2332
                     /locus_tag="ACL72M_001044"
     CDS             1055..2332
                     /locus_tag="ACL72M_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGS0716181.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2408..3892
                     /gene="thrC"
                     /locus_tag="ACL72M_001045"
     CDS             2408..3892
                     /gene="thrC"
                     /locus_tag="ACL72M_001045"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGS0716182.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3953..5233
                     /locus_tag="ACL72M_001046"
     CDS             3953..5233
                     /locus_tag="ACL72M_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS0716183.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5237..5857
                     /locus_tag="ACL72M_001047"
     CDS             5237..5857
                     /locus_tag="ACL72M_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0716184.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6023..7135
                     /locus_tag="ACL72M_001048"
     CDS             6023..7135
                     /locus_tag="ACL72M_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS0716185.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7458..7883
                     /locus_tag="ACL72M_001049"
     CDS             7458..7883
                     /locus_tag="ACL72M_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS0716186.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7894..8253
                     /locus_tag="ACL72M_001050"
     CDS             7894..8253
                     /locus_tag="ACL72M_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGS0716187.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8360..9004
                     /gene="pcp"
                     /locus_tag="ACL72M_001051"
     CDS             8360..9004
                     /gene="pcp"
                     /locus_tag="ACL72M_001051"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGS0716188.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(9032..9889)
                     /locus_tag="ACL72M_001052"
     CDS             complement(9032..9889)
                     /locus_tag="ACL72M_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGS0716189.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10019..11161
                     /gene="tgt"
                     /locus_tag="ACL72M_001053"
     CDS             10019..11161
                     /gene="tgt"
                     /locus_tag="ACL72M_001053"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGS0716190.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11259..13076
                     /locus_tag="ACL72M_001054"
     CDS             11259..13076
                     /locus_tag="ACL72M_001054"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS0716191.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13229..14380
                     /gene="nagA"
                     /locus_tag="ACL72M_001055"
     CDS             13229..14380
                     /gene="nagA"
                     /locus_tag="ACL72M_001055"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGS0716192.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14543..15601
                     /locus_tag="ACL72M_001056"
     CDS             14543..15601
                     /locus_tag="ACL72M_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGS0716193.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15752..16117
                     /locus_tag="ACL72M_001057"
     CDS             15752..16117
                     /locus_tag="ACL72M_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGS0716194.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16193..17134
                     /gene="comGA"
                     /locus_tag="ACL72M_001058"
     CDS             16193..17134
                     /gene="comGA"
                     /locus_tag="ACL72M_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGS0716195.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17082..18098
                     /gene="comGB"
                     /locus_tag="ACL72M_001059"
     CDS             17082..18098
                     /gene="comGB"
                     /locus_tag="ACL72M_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGS0716196.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18100..18426
                     /gene="comGC"
                     /locus_tag="ACL72M_001060"
     CDS             18100..18426
                     /gene="comGC"
                     /locus_tag="ACL72M_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HGS0716197.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18419..18823
                     /gene="comGD"
                     /locus_tag="ACL72M_001061"
     CDS             18419..18823
                     /gene="comGD"
                     /locus_tag="ACL72M_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGS0716198.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18786..19088
                     /gene="comGE"
                     /locus_tag="ACL72M_001062"
     CDS             18786..19088
                     /gene="comGE"
                     /locus_tag="ACL72M_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGS0716199.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19051..19512
                     /gene="comGF"
                     /locus_tag="ACL72M_001063"
     CDS             19051..19512
                     /gene="comGF"
                     /locus_tag="ACL72M_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGS0716200.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19490..19936
                     /gene="comGG"
                     /locus_tag="ACL72M_001064"
     CDS             19490..19936
                     /gene="comGG"
                     /locus_tag="ACL72M_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGS0716201.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            20039..20626
                     /locus_tag="ACL72M_001065"
     CDS             20039..20626
                     /locus_tag="ACL72M_001065"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0716202.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKVILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20687..21640
                     /locus_tag="ACL72M_001066"
     CDS             20687..21640
                     /locus_tag="ACL72M_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0716203.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21691..22881
                     /locus_tag="ACL72M_001067"
     CDS             21691..22881
                     /locus_tag="ACL72M_001067"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGS0716204.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYFAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22882..23013
                     /locus_tag="ACL72M_001068"
     CDS             22882..23013
                     /locus_tag="ACL72M_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716205.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            23030..23401
                     /gene="rnpA"
                     /locus_tag="ACL72M_001069"
     CDS             23030..23401
                     /gene="rnpA"
                     /locus_tag="ACL72M_001069"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGS0716206.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23376..24200
                     /locus_tag="ACL72M_001070"
     CDS             23376..24200
                     /locus_tag="ACL72M_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS0716207.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24219..25205
                     /gene="jag"
                     /locus_tag="ACL72M_001071"
     CDS             24219..25205
                     /gene="jag"
                     /locus_tag="ACL72M_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGS0716208.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25256..25879
                     /locus_tag="ACL72M_001072"
     CDS             25256..25879
                     /locus_tag="ACL72M_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGS0716209.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26010..27467
                     /locus_tag="ACL72M_001073"
     CDS             26010..27467
                     /locus_tag="ACL72M_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0716210.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27490..27771
                     /locus_tag="ACL72M_001074"
     CDS             27490..27771
                     /locus_tag="ACL72M_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0716211.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27848..28333
                     /locus_tag="ACL72M_001075"
     CDS             27848..28333
                     /locus_tag="ACL72M_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0716212.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGLYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28350..29015
                     /locus_tag="ACL72M_001076"
     CDS             28350..29015
                     /locus_tag="ACL72M_001076"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGS0716213.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29019..29882
                     /locus_tag="ACL72M_001077"
     CDS             29019..29882
                     /locus_tag="ACL72M_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGS0716214.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29884..30588
                     /locus_tag="ACL72M_001078"
     CDS             29884..30588
                     /locus_tag="ACL72M_001078"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGS0716215.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30767..32440
                     /locus_tag="ACL72M_001079"
     CDS             30767..32440
                     /locus_tag="ACL72M_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0716216.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            32552..33643
                     /gene="ulaG"
                     /locus_tag="ACL72M_001080"
     CDS             32552..33643
                     /gene="ulaG"
                     /locus_tag="ACL72M_001080"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGS0716217.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33757..35733
                     /gene="tkt"
                     /locus_tag="ACL72M_001081"
     CDS             33757..35733
                     /gene="tkt"
                     /locus_tag="ACL72M_001081"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS0716218.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35850..36149
                     /gene="yajC"
                     /locus_tag="ACL72M_001082"
     CDS             35850..36149
                     /gene="yajC"
                     /locus_tag="ACL72M_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS0716219.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36196..36624
                     /locus_tag="ACL72M_001083"
     CDS             36196..36624
                     /locus_tag="ACL72M_001083"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGS0716220.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36626..37036
                     /locus_tag="ACL72M_001084"
     CDS             36626..37036
                     /locus_tag="ACL72M_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGS0716221.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37336..39987
                     /gene="adhE"
                     /locus_tag="ACL72M_001085"
                     /gene_synonym="adhC"
     CDS             37336..39987
                     /gene="adhE"
                     /locus_tag="ACL72M_001085"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGS0716222.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12221 a         7217 c         9064 g        11771 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttaacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tattggggta tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga
      841 atccagctac cccagttact atttgccggc gtggcggaat tggcagacgc gctggactca
      901 aaatccagtg tccgcaagga cgtgccggtt cgaccccggc cgccggtata gtatagtgtt
      961 aggaacgttg ttattcttcg ttcctttttt atattatttt tggtataatt atagttattc
     1021 aaattttatt tagattaaga aagtgtaggg gagtatgtct tgttctatcg atttattaaa
     1081 acatcggtat ttgaaaaata ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga
     1141 gtatcctgtt gcaagtttag aaggggatgc tacagatgtt gaagttatga aggatctatt
     1201 tcattattta gtttctactt tggatctcac cgtagcaaag gtagatgatt ttggcaatct
     1261 gatccagtta gtagatccga taagtcagga tgctatttta tttgaagttt cctatacaac
     1321 gattgagttt gcatttggta aggctgaaac gattcaagag gtcgaaaatc gtttcaataa
     1381 ttatatgaat gtaattcaga gaaagttagc tgaatcaaat catgctattg ttggctgtgg
     1441 tatccatccc aactgggata aaaatgagaa ttgtccagtg gcttatccac gctatcagat
     1501 gttgatggat tatttgaatt tgagtagaaa tattattaaa tcagatttac atcatttccc
     1561 tgaatatggt acttttatct gtgggagcca ggttcagctg gatatttcaa aaaccaacta
     1621 cttacgggtg attaatgctt ttactcaaat tgaagcggct aaggcttatt tatttgcaaa
     1681 ctctgaattt tcgggtgcgg attgggatac gaaaatttca agggatattt tctgggaaga
     1741 atctatgcat ggtatctatc cagagaatgt tggggtcaat gctagactcc ttaatgatga
     1801 agctgatttt tttgactatc taaatcattc tgcgattttt actgcggaac gtgatgggca
     1861 gacctattat ttttatccta ttcaggctgg ggactatttg gctacgtccg aaatccaagc
     1921 atttgctctg aatggggatg aggttattat ttacccccaa gagaaggatt ttgaaactca
     1981 tcgtagttac cagtaccaag atttaacgac tcgaggaaca gttgagtttc gtagtgtgtg
     2041 tacacagcca cttgatagga cttttgcttc tgcagctttt cacttgggat tattggttaa
     2101 tttagacaag ttagaagctt acttagaaac agcacctttc tttaaagtat ttggttatga
     2161 ttacaagtct ttaaggagac aattttctaa gaaaaatctt acagatgagg aagaaactac
     2221 gattattgaa ttttccaaag acttactcct actagctgag gagggactag tggtgagaaa
     2281 taaggaagaa atgacctatt tacagccttt gagagaagaa ttgagcctat aatttctctt
     2341 ataaagggag aattttctga aaaatcatga tataatggac gagactatag ataaaggata
     2401 gagagtaatg acattagttt atcaatcaac gcgtgatgcc aacaatacag taactgccag
     2461 ccaagcaatt ttgcaaggtt tggcgacgga cggcggtttg tttacaccgg atacttatcc
     2521 aaaggtagat ttgaactttg acaaattgaa agatgcttct taccaggaag ttgctaagct
     2581 agttttgtca gcatttttag atgactttac agttgaggag ttggactact gtatcaacaa
     2641 tgcctacgat agcaaatttg atactccagc tattgcacca ttagtgaaat tagatgggca
     2701 atacaatttg gaacttttcc atggttcaac gattgccttt aaggatatgg ccttgtctat
     2761 tttgccatac tttatgacga ctgctgctaa gaaacatggt ttggagaaca agattgttat
     2821 cttgacagcg acatctggtg acacggggaa agctgctatg gcggggtttg cgaatgtgcc
     2881 tggtactgag attatcgtct tttatccaaa ggatggtgtc agcaagattc aagagttaca
     2941 aatgaccact cagactggcg acaatactca tgttattgct attgatggta actttgacga
     3001 tgcgcaaaca aatgtgaagc acatgtttaa cgacgtggct cttcgtgaaa aattgactac
     3061 caacaagttg caattttcat cagctaactc tatgaacatt ggtcgtctgg tgccacaaat
     3121 tgtttattat gtttatgctt acgctcaatt ggttaagact ggtgaaattg tagctggtga
     3181 aaaggttaac ttcacagtac caacaggaaa ctttggaaat atcttggctg ccttttatgc
     3241 caaacaaatt ggtttgccag ttggtaaatt aatctgtgct tcaaatgaca acaatgtttt
     3301 gacagacttc tttaaaacac gtgtctatga caaaaaacgt gagtttaagg taacaaccag
     3361 cccatctatg gatatcttgg tatcttcaaa cttggagcgc ttgattttcc atcttttggg
     3421 aaataatgct gaaaagacaa ctgaacttat gaatgccttg aacacgcaag gacaatataa
     3481 gttgacagac tttgatgcag agattttgga cctctttgca gctgaatatg cgactgagga
     3541 agaaacggca gcagagatca agcgtgtttg tgagttagat tcttatatcg aggaccctca
     3601 tacagctgtt gcttcagcag tttataaaaa ataccaatcg gccactggag atgtaactaa
     3661 gacagtgatt gcttcaacag ctagtccata caagttccca gtagttgcag tagaagctgt
     3721 aactggaaaa gcaggtttaa cagactttga agccttggct caattacatg aaatctcagg
     3781 cgttgcagtg ccaccagcag ttgatgggct tgaaatagct ccaattcgtc acaagacaac
     3841 agtggcagct gctgacatgc aagcagcggt tgaggcttat ttaggacttt aagacagagg
     3901 gagcaaactc ggttgggaaa ccaactgagt ttcttttcat caggaggaga gattgtttaa
     3961 gaaaaataaa gacattctta atattgcatt gccagctatg ggtgaaaact ttttgcagat
     4021 gctaatggga atggtggaca gttatttggt tgctcattta ggattgatag ctatttcagg
     4081 ggtttcagta gctggtaata ttatcaccat ttatcaggcg attttcatcg ctctgggagc
     4141 tgctatttcc agtgttattt caaaaagcat agggcagaaa gaccagtcga agttggccta
     4201 tcatgtgact gaggcgttga agattacctt actattaagt ttccttttag gatttttgtc
     4261 catcttcgct gggaaagaga tgataggact tttggggacg gagagggatg tagctgagag
     4321 tggtggactg tatctatctt tggtaggcgg atcgattgtt ctcttaggtt taatgactag
     4381 tctaggagcc ttgattcgtg caacgcataa tccacgtctg cctctctatg ttagtttttt
     4441 atccaatgcc ttgaatattc ttttttcaag tctagctatt tttgttctgg atatggggat
     4501 agctggtgtt gcttggggga caattgtgtc tcgtttggtt ggtcttgtga ttttgtggtc
     4561 acaattaaaa ctgccttatg ggaagccaac ttttggttta gataaggaac tgttgacctt
     4621 ggctttacca gcagctggag agcgacttat gatgagggct ggagatgtag tgatcattgc
     4681 cttggtcgtt tcttttggga cggaggcagt tgctgggaat gcaatcggag aagtcttgac
     4741 ccagtttaac tatatgcctg cctttggcgt cgctacggca acggtcatgc tgttggcccg
     4801 agcagttgga gaggatgatt ggaaaagagt tgctagtttg agtaaacaaa ccttttggct
     4861 ttctctgttc ctcatgttgc ccctgtcctt tagtatatat gtcttgggtg taccattaac
     4921 tcatctctat acgactgatt ctctagcggt ggaggctagt gttctagtga cactgttttc
     4981 actacttggg acccctatga cgacaggaac agtcatctat acggcagtct ggcagggatt
     5041 aggaaatgca cgcctccctt tttatgcgac aagtatagga atgtggtgta tccgcattgg
     5101 gacaggatat ctgatgggga ttgtgcttgg ttggggcttg cctggtattt gggcagggtc
     5161 tctcttggat aatggttttc gctggttatt tctacgctat cgttaccagc gctatatgag
     5221 cttgaaagga taggaaatgc aaaaaacagc ttttatttgg gatttagacg ggactttatt
     5281 ggactcttac gaagcgattt tatcagggat tgaggagact tttgctcagt tttctattcc
     5341 ttatgataag gagaaggtga gagagtttat cttcaagtat tcggtgcaag atttgcttgt
     5401 gcgggtggca gaagatagaa atctggatgt tgaggtgcta aatcaggtgc gtgcccagag
     5461 tctggctgag aagaatgctc aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg
     5521 ggcagacgaa tcaggaattc agcagtttat atatactcat aaggggaaca acgcttttac
     5581 cattctcaag gacttggggg tggaatccta ttttacagag attttaacca gtcagagtgg
     5641 ctttgtgcgg aagccaagtc cagaagcggc tacctatctg ctagataagt atcagttgaa
     5701 ttctgataat acttattata taggggatcg gactctggat gtggaatttg cccagaatag
     5761 tgggattcaa agcatcaact ttttagagtc tacttatgaa gggaatcaca ggattcaagc
     5821 gttagcagat atttcccgta tttttgagac taagtgataa aaagattgtg tcagttttgt
     5881 gacagagacc taacaaacta tttcaagtaa cctagtttgt tacaaggaat agacagttct
     5941 gttaaatagg cccgagaggg ctttttttct acattttttg tgttatgata gacaggtact
     6001 catttgaaag gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa cagtagcctt
     6061 gtcatttgcc ccagtattgg caactcaagc agaagaagtt ctttggactg cacgtagtgt
     6121 tgagcaaatc caaaacgatt tgactaaaac ggacaacaaa acaagttata ccgtacagta
     6181 tggtgatact ttgagcacca ttgcagaagc cttgggtgta gatgtaacag tgcttgcgaa
     6241 tctgaacaaa atcactaata tggacttgat tttcccagaa actgttttga caacgactgt
     6301 caatgaagca gaagaagtaa cagaagttga aatccaaaca cctcaagcag actctagtga
     6361 agaagtgaca actgcgacag cagatttgac cactaatcaa gtgaccgttg atgatcaaac
     6421 tgttcaggtt gcagaccttt ctcaaccaat tgcagaagtt acaaagacag tgattgcttc
     6481 tgaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacga ccgaaacaac
     6541 tcgcccagtt gaagaagcaa ctcctcagga aacgactcca gctgagaagc aggaaacaca
     6601 agcaagccct caagctgcat cagcagtgga agtaactaca acaagttcag aagcaaaaga
     6661 agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag aagagacgaa
     6721 aataatttca acaacttacg aggctccagc tgcgcccgat tatgctggac ttgcagtagc
     6781 aaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc tttaaagaag aaattgctaa
     6841 cttgtttggc attacatcct ttagtggtta tcgtccagga gacagtggag atcacggaaa
     6901 aggtttggct atcgacttta tggtaccaga acgttcagaa ttaggggata agattgcgga
     6961 atatgctatt caaaatatgg ccagccgtgg cattagttac atcatctgga aacaacgttt
     7021 ctatgctcca ttcgatagca aatatgggcc agctaacact tggaacccaa tgccagaccg
     7081 tggtagtgtg acagaaaatc actatgatca cgttcacgtt tcaatgaatg gataaacccg
     7141 acttgataac atcattttga cgaatgagat ctagctttcg tgatggaaag cgattctcgt
     7201 tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa ccacgtcagt tttatctgaa
     7261 acttcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctt tttgattttc
     7321 attgagtatc aatttgaatg gaaaatggaa agttatcatc ttgtaatgag ttaagcaaca
     7381 ttcttgcaat ctattttact ttatatcaca attaattagt caaatattga taaatcaata
     7441 aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc cgcttgtctg
     7501 agcaagcgag tacgcaattg tttgaaaaaa ggcttgggat tagtttgaca cggtatcaga
     7561 ttttactgtt tttgctggag cattctcctt gtaaccaaat ggcggttcag gagcgtttga
     7621 aaattgatca ggctgctttg acacggcatt tcaaaatttt ggaaacggaa ggtttggtgg
     7681 agcgtcatcg taatcctgaa aatcagcggg aagtgttggt agaggctgcg aagtatgcca
     7741 aggagcagtt agtggtgaat ccccctctgc aacatatcag ggttaaggaa gagatagaaa
     7801 gtatcttaac agagtttgag agaacagaac tcagccgttt attaaataaa ttggttttgg
     7861 gtattgaaaa tatagaaatt taaggaaaaa tagatgtcaa ttattttaac aacgatcgtt
     7921 gctttggagc atttttacat tttttatttg gaaagtattg ccacgcaatc agatgcgact
     7981 agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag ttcattgttc
     8041 aaaaatcaag gaatttataa ggctctgcta ggagtctttc tcttgtatgt catttatttc
     8101 tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc tgcgacttac
     8161 ggctctttaa cagcggataa aaaaattatt ttgaaacaag gtggatcagc tattttggcc
     8221 ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc gctaatcctt
     8281 tttaatccag aataagggaa atatgttata cttgttttta agaaaaaagt ctcattgaat
     8341 tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct ttggagggga
     8401 aaagggcaat ccagctttgg aggccattaa aggtttacca gctgaaatcc atggtgctga
     8461 ggtccgttgg ctagaggtgc cgacagtttt tcacaaatct gctcaagtat tggaagaaga
     8521 gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg gaagaactag
     8581 tttgacacct gaacgagtga ccattaatca agacgatgca tgcatttctg ataacgaaga
     8641 taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact ttagtagttt
     8701 gccgattaaa gcgatggttc aagctataaa aaaagagggc ttaccggcct ctgtttccaa
     8761 tacggcaggg acttttgtct gcagccattt gatgtatcag gctctctatt tggtagaaaa
     8821 gaaatctcca tatgttaagg caggttttat gcatattcct tatatgatgg aacaggtggt
     8881 gaacagaccg actactccag ctatgagttt agtggatatt cggcgaggga tagaagcagc
     8941 aatcggcgct ataatagaac atggagatca ggaactcaag ttggtaggcg gagaaactca
     9001 ttgatagaaa aaagcttgag gagaaaaacc ttcaagcttt tggacgtttt cgggccaata
     9061 ctgctcggta aaacataatt ttagtgcatt ggatataagg taggagtgaa aaactagcaa
     9121 tgccaaaggt aatccaattg aggaagtacc aaggaagaag ctgtaaatct aggacaaagt
     9181 gctggaactt gtagcccttc ataaaggaac ggctagtttt taggattcgt cttggtggga
     9241 cctgtcctag gtctagacta taacagagaa gaaattccac ctgtgaatag gcataatact
     9301 gtggaatata gaggatattt cctacaatga tcaagatgag acttgcaaga aagtagagtc
     9361 caaagaccat gaggaaacgc tcggtttcaa ctgatgagag atctagattt ggaaactcag
     9421 gatgtagggt gacgaatttt ttggctaaaa agctactata aaagaggagg taaatcccaa
     9481 gtaaattagg gatactccat aaaaagagat agaaacgttt gagaagtagg gtcaaaaagg
     9541 tttgagaaaa gcgctcctca tcaaagagag ctaggctgtt ttttacagat ggctccgttt
     9601 tagaatcttt catgagtgtc agtgttgcat agacggaact ggtcaaaaga atagtcccga
     9661 taaaggagac tagtagagga aagaggtagg tttgaagtat ttggccaagt atgctgaaaa
     9721 atggctgttc taaaacagtc ccgtggatcc gagataaggg attaagaaaa ccagataaga
     9781 tgaccagcat actgggaagg atatagagga gaaagagacg gggggtgtca gcctgaaaat
     9841 gttttgactc ctgacgaatt gtttttaaat caatttttgg atagttcatt ctcttattat
     9901 accatagttc ttatacatag ttcgtgacag ttcctacttt ttttgataaa atcatacagt
     9961 gtgtccttgg gcacactgta tgaactggga ctgtctttcc cagcttcgga ggtaaaaaat
    10021 gtcagattca ccaatcaaat atcgtttgat taagaaagaa aaacacacag gagctcgtct
    10081 gggagaaatc atcactcccc acggtacctt tccgacacct atgtttatgc cagttgggac
    10141 acaagccact gtcaaaactc agtcacctga agaattgaag gagatgggtt cgggaattat
    10201 cctatcaaac acctatcatc tctggcttcg ccctggagat gaactcattg cacgcgctgg
    10261 tggtctccac aagttcatga attgggacca gcctatcttg acagatagtg gtggttttca
    10321 ggtttattct ttagcagata gccgtaatat cacagaagaa ggagtaacct ttaaaaatca
    10381 tctaaatggt tctaagatgt tcctatcccc agaaaaagcc atctctattc agaataatct
    10441 gggttcagac atcatgatgt cctttgatga atgtcctcag ttttatcaac cttatgacta
    10501 cgttaagaaa tcgatcgagc gtaccagccg ttgggctgag cgtggtttga aggctcaccg
    10561 tcgtccacat gaccaaggtt tgtttggaat tgtgcaaggt gcaggatttg aagaccttcg
    10621 ccgccaatca gctcatgatc ttgtcagcat ggatttctca ggctactcta tcggtggttt
    10681 ggcagtggga gaaacccatg aagagatgaa tgcggtcttg gactttacaa ctcaactgct
    10741 acctgaaaat aaacctcgtt atctgatggg tgtgggagcg ccagatagct tgatcgatgg
    10801 ggtcattcgt ggggtggata tgtttgactg tgtcttaccg actcgaattg ctcgtaacgg
    10861 gacttgtatg accagtcaag gacgtttggt tgtgaaaaat gcccagtttg ctgaggactt
    10921 tacgccactg gatcctgagt gtgactgcta cacatgtaat aactatacac gcgcttacct
    10981 tcgtcacctg ctcaaggctg atgaaacctt tggtatccgc ttgactagct accacaatct
    11041 ttacttcttg cttaacctga tgaagcaagt gcgacaagcc atcatggatg acaatctctt
    11101 ggaattccgt gagtattttg tggaaaaata tggctataat aagtcaggac gtaatttcta
    11161 aaatggaatt gatataaaaa aatcctaagt tttctcttag gatttttctt ctttttttga
    11221 tagaataaag tgtacaatga aaggaagaat aaactcgtat gcgcattaaa tggttttcct
    11281 tgattaggat tataggttta cttttggtac tcttgtatca cttctttcag acgatctttc
    11341 ctggaggatt tttcggggta gatgtctttt tcacattttc aggtttcctg attacagctc
    11401 tactcattga agaattttct aagaacaatg agattgattt gataggattt tttagaagac
    11461 gcttttatcg gattgtgcca cctgtggttt tgatggtctt ggtgaccatg ccttttactt
    11521 tcttggttcg ccaagactat gttgctggaa ttggtggcca gattgcgggc gtcttaggct
    11581 ttatgaccaa cttctatgaa ctcctaacag gtgggagtta tgaatctcag ttcattcctc
    11641 atttgtttgt tcataattgg agtttggcag ttgaggttca ctactatatt ctttggggat
    11701 tggcagtttg gttcttatcc aaacaagcta aatcaaatgg tcagttgaag gggatggtct
    11761 ttctcttatc tgctgctgcc ttcttgatca gtttcttctc catgtttatt ggtagttttc
    11821 tagtgacctc ttattcctct gtttatttct ccagtttaac tcatgtctat ccattctttt
    11881 tgggaagtat gttagcaact attgtaggtg ttcgtcagac gacttccctc gtcaagcagt
    11941 tggataaaat ctgggattta cgaaagactt tggtagtttt tggaggaggc tttggtttcc
    12001 tagttctttt gactttcttt gtcaaattca cttatctttt tgcctatctt atcggcttct
    12061 tgcttgccag tcttgcagct cttgccatga ttctggcggc gcgtgtctta catgaaaaga
    12121 cacatcatat acaggagccg aagattatca gctttttagc ggatactagc tatgcggttt
    12181 atcttttcca ttggcctttc tatatcattt tctcacagtt gacatcaaat cttcttgctg
    12241 tattactgac tctgatttgt tcttatggct ttgccagtct gtcattctat gtattggaac
    12301 cttggattgc aggcaagaac acacctattt tacaaactct tcgtcccctg ccttatattc
    12361 acgcaattct tgtagcaggt acaggaatct tgaccatcat tgtctgcacg gtgaccttgt
    12421 tggcaccaca agtgggagcg tttgagacag acttgactgt caatggcttg aagcaagctg
    12481 caacaaatat tggccagacc aaggtgatgg cagaacgggc agatgcaaac agtttgggaa
    12541 ttgctgatgg cactatgtta attggtgact cagtggcttt aagggcaaat acagcactac
    12601 agacagctct tcctggagca cagattaacg cgcaggtcag cgtaacaacc aagaccgcaa
    12661 atgaaatcat gctaaataat agccagaata aatttttacc taagacggtg gtcattgcga
    12721 ctggggtaaa taatcctgag aattacaagg atgactggga cagtatcgtg aaaaatcttc
    12781 ctaagggaca ccatatgatt ttggtgactc cttatgaggg agataagaca aaagagacct
    12841 atgccatcgt tgagaaggct gctgcctata tgagagaatt ggcagagaag acaccttaca
    12901 ttacgatagc agattggaat caagttgcga aagagcatcc agaaatttgg gctggaacag
    12961 accaggttca tttcgggagt gagagtagca ctatcgaagc aggagcaaaa ttgtatgcag
    13021 atacgattgc cacagctttg cagacagctc aagacaagcc ggttaaatca aaataacttg
    13081 tattaaaaaa gagaagagtt ggagaaatcc agctctttta aaatatctcc aaaaaatagg
    13141 tctataccat ttacaaataa aaaagaaagg tttataatgt aattgacata ataaattgta
    13201 gaatcaatct tttaaggagg ttaacattat gcctaactat attaaagcgg atcagttttt
    13261 ctacccacac ggagttcgtc gaggtggtta cttggaactt gtggacggca agtttgggaa
    13321 acatgtagag cagattcctg aaggggctga ggtgattgac tatacaggtt atagcattgc
    13381 cccaggtctt gtggatactc atattcatgg atatgcaggt gtagatgtga tggacaacaa
    13441 cattgaaggt acattgcata ctatgagtga aggacttctt agtaccggtg ttaccagttt
    13501 cttacccaca actttaacag ccacttatga gcaattgctt gcagtcactg aaaatcttgg
    13561 aaaccattat aaagaagcaa caggtgctaa gattcgtggg atttattatg aaggtccata
    13621 tttcacagaa acttttaagg gggcacaaaa tccaacttat atgagagacc cgggtgttga
    13681 ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt aataaaattg cccttgcacc
    13741 agaacgtgat ggggtggaag actttgttcg tacagttacg ggcgaaggtg tgacggttgc
    13801 tcttggacat tcaaacgcga cttttgatga agccaaaaaa gcagtcgatg ctggagcgag
    13861 tgtttgggtg catgcctata atggaatgcg tgggttgact caccgtgaat tgggtatggt
    13921 tggagccatg taccaattgc cacataccta tgcagagttg atctgtgatg gtcaccacgt
    13981 agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga acagaaaaca tcgctcttat
    14041 cacagactgt atgacagctg ggggattgga agacggagat tatatgttgg gagaattccc
    14101 agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca ggtaacttgg caggttctat
    14161 cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg ggaattgcga atccgcatga
    14221 agcagtcatg atggccagct tcaacccagc taaatccgtt cacatcgatg acgtctgtgg
    14281 ccaaatccgt gaaggctacg acgctgactt catcgtatta gataaagatt tggaattggt
    14341 agcaacctat ctagatggcg taaaacgtta tcaagcataa gagagaaggc agaagttaga
    14401 gactagcttc tgctttttta tacagggtac tttactggta aataaaaagt taaaaaaatc
    14461 acaaaaaaag cttgaagaaa caaagaaaaa ggcttacaat tgaactataa atattacaaa
    14521 taaaaaaacg gaggagtgct ttatgaaagc ctatacttat gttaaaccag gacttgcttc
    14581 ttttgttgat gtagacaaac cagttattcg caagccaaca gacgctattg tgcgtattgt
    14641 aaaaaccact atttgtggaa cagacctcca tattatcaaa ggggatgttc ctacttgcca
    14701 aagtggtacc attcttggcc acgaagggat tgggattgtt gaagaagttg gggaaggagt
    14761 ttccaacttc aaaaaaggcg acaaggtctt gatttcttgc gtctgtgcct gtggtaaatg
    14821 ctactactgt aaaaaaggaa tttatgccca ctgtgaagac gaagggggct ggattttcgg
    14881 tcacttgatt gatggtatgc aggctgaata tctacgtgtc cctcatgcag ataatactct
    14941 ttaccatact ccagaagact tgtcagatga agctttggtt atgctgtcag acattctgcc
    15001 tactggatat gaaattggtg tcttaaaagg gaaagtagaa cctggttgca gcgtagccat
    15061 tattggttca ggtccagttg gattggctgc tcttttaaca gcccaattct attcaccagc
    15121 taaattgatt atggtagacc tagacgataa ccgcttggaa actgccctat cattcggtgc
    15181 gactcataag gttaattctt cagaccctga aaaagccatt aaagaaattt atgatttgac
    15241 agatggtcgt ggtgtggatg tcgctatcga agctgttggt attcctgcaa catttgattt
    15301 ctgtcaaaag attatcggtg tagacggaac ggttgccaac tgtggtgtgc atggtaaacc
    15361 agttgaattc gatttagata aactttggat tcgcaacatc aatgtaacaa ctggtttggt
    15421 atctacaaat acgactccac aattgttgaa agcacttgaa agtcataaga ttgaaccaga
    15481 aaaattggta actcactatt tcaaactcag tgaaattgaa aaagcctatg aagtcttcag
    15541 taaggcagca gaccaccatg ccattaaggt cattatcgaa aacgatatct cagaagccta
    15601 agtagtaaaa atatttttgt acataagtaa atagaaattc agtcatccat cagatggctg
    15661 gattttttat caaaaaatta agaaatgagc atatttcttt ccttgtctgg cggaattggt
    15721 tataatatac ggtacaaagg aatgaatgaa tatgtatcgt gttatagaaa tgtacggaga
    15781 ttttgaaccg tggtggttct tagaaggttg ggaagaagat attgtagcaa gtagaaaatt
    15841 tgaccagtat tatgatgctc tcaaatacta caaaacttgc tggtttagat tggaacaaga
    15901 atcccctctt tataaaagta gaagcgactt gatgaccatt ttttgggacc cggaagacca
    15961 acgctggtgt gatgaatgtg atgagtattt acaacaatac cattctttgg ctcttttgca
    16021 ggatgagcag gttatcccag acgaaaaact acgctcaggc tatgaaaaac aaaccagtca
    16081 ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga aaagtaactt ttttggagtt
    16141 gcttttttta tttttctaac gctttgcgaa tagtataggt gaggaggtaa gtatggttca
    16201 agaaattgca caagaaatca ttcgttcagc tcggaaaaaa gggacgcagg atatttattt
    16261 tgtccctaag ttagacgcct atgagcttca tatgagggta ggagacgagc gctgtaaaat
    16321 tggtagctat gattttgaaa agtttgcagc cgttatcagt cactttaagt ttgtggcggg
    16381 tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc tgtgattatg cctatgacca
    16441 gaagatggcg tctctacgtt tatctactgt aggcgattat cgggggcatg agagtttggt
    16501 tatccgtttg ttgcacgatg aggagcagga cttgcatttt tggtttcagg atattgaaga
    16561 attaggcaag cagtacaggc aacggggact ctatcttttt gctggtccgg ttgggagtgg
    16621 taagacgacc ttgatgcatg aattgtccaa gtcactcttt aaaggacagc aagttatgtc
    16681 catcgaagat cctgtcgaaa tcaagcagga cgacatgctt cagttgcagt tgaacgaagc
    16741 aatcggccta acctatgaaa atctaatcaa actttccttg cgtcatcgac cagatctctt
    16801 gattatcgga gaaattcgtg acagcgagac ggcgcgtgca gtggtcagag ctagtttgac
    16861 aggtgcgaca gtcttttcaa ccattcacgc caagagtatc cgaggtgttt atgagcgtct
    16921 gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt ctgcaaggag tctgctacca
    16981 gagattaatc gggggaggag gaatcgttga ctttgcaagc agagattatc aagaacacca
    17041 agcagccaag tggaatgagc aaattgacca gcttcttaaa gatggacata tcacaagtct
    17101 tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa aaatatcatc accctattta
    17161 acaatctctt ttctagcggt tttcatctgg tggagactat ctccttttta gataggagtg
    17221 ctttgttgga caagcagtgt gtgatccaga tgcgtgcggg cttgtctcag gggaaatcat
    17281 tctcagaaat gatggaaagt ttgggatgtt caagtaccat tgtcactcag ttatctctag
    17341 ctgaagttca tggcaatctt cacctgagtt tgggaaagat agaagaatat ctagacaatc
    17401 tggccaaggt caagaaaaag ttaattgaag tagcgaccta tcctttgatt ttgctgggtt
    17461 ttcttctctt aattatgctg gggctacgga attacctgct cccacaactg gatagtagca
    17521 atattgccac ccgaattatc ggtaatctgc cacaaatttt tctaggcatg gtagggcttg
    17581 tttccgtgct tgccctttta gcactaactt tttataaaag aagttctaag atgagtgtct
    17641 tttctatctt agcacgcctt ccctttattg gaatctttgt gcagacctac ttgacagcct
    17701 attatgcacg tgaatggggg aatatgattt cacagggaat ggagctgacg cagatttttc
    17761 aaatgatgca ggaacaaggt tcccagctct ttaaagaaat cggtcaagat ctggctcaaa
    17821 ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac ctatcctttc tttaggaagg
    17881 aattgagtct catcatagag tatggggaag ttaagtccaa gctgggtagt gagttggaaa
    17941 tctatgctga aaaaacttgg gaagcctttt ttacccgagt caaccgcacc atgaatttgg
    18001 tgcagccact ggtttttatc tttgtggcac tgattatcgt tttactttat gcggcaatgc
    18061 tcatgcccat gtatcaaaat atggaggtaa atttttaaaa tgaaaaaaat gatgacattc
    18121 ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga tgttagtagt cttgctgatt
    18181 atcagcgtgc ttttcttgct ctttgtacct aatctgacca agcaaaaaga agcagtcaat
    18241 gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc aggcagaact ttatagcttg
    18301 gataaaaatg aagatgctac tctgagcaag ttacaaggag atgggcgcat cacggaagaa
    18361 caggttaaag cttataatga atactatact aaaaatggag gggcaaatcg taaagtcaat
    18421 gattaaggcc tttaccatgc tggaaagtct cttggttttg ggacttgtga gtatccttgc
    18481 cttgggctta tccagctctg tccagtccac ttttgcagca gtagaggagc agattttctt
    18541 tatggagttt gaagaactct atcgggaaac ccaaaaacgc agtgtagcca gtcagcaaaa
    18601 gactagtcta aatttagatg ggcagacgct tagcaatggc agtcaaaagt tgacagttcc
    18661 taaaggaatt caggcaccat caggccaaag tattacattt gaccgagctg ggggcaattc
    18721 gtccctggct aaggttgaat ttcagaccag taaaggagcg attcgctatc aattatatct
    18781 aggaaatgga aaaattaaac gcattaagga aacaaaaaat tagggcagtg attttactgg
    18841 aagcagtagt cgctctagct atctttgcca gcattgcgac cctccttttg ggacaaattc
    18901 aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga agaagtcttg agggtagcta
    18961 agatggccct gcagacgggg caaaatcagg taagcatcaa cggagttgag attcaggtat
    19021 tttctagtga aaaaggattg gaggtctacc atggttcaga acagttgttg gcaatcaaag
    19081 agccataagg tcaaggcttt taccttgtta gaatccctgc ttgccctcat tgtcatcagt
    19141 gggggattac tcctttttca aactatgagt cagctcctca tttcagaagt tcgctaccag
    19201 caacaaagcg agcaaaagga gtggctcttg tttgtggacc aacttgaggc agaattagac
    19261 cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca tgaagcaaga tggcaaggac
    19321 atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa ccgatgctag tggacggggg
    19381 tatcagccta tggtttatgg cctcaaatca gctcagatta cagaggacaa tcaactggtt
    19441 cattttcgtt tccagtttca aaaaggctta gaaagggagt tcatctatcg tgtggaaaaa
    19501 gaagaaagtt aaggcaggtg ttctcctcta cgcagtcacc atagcagcca tctttagtct
    19561 tttgttgcaa ttttatttga accgacaaat cgcccactat caagactatg ctttaaataa
    19621 agaaaaattg gttgcttttg ccatggctaa acgaaccaag gataaagccg agcaagaaag
    19681 tggggaacag gtttttaatc taggtcaggt aagctatcaa aacaagaaaa caagcttggt
    19741 gacgactgtt cgtacgtcta agagccaata tgagtttctg tttccttcag tcaaaatcaa
    19801 agaagagaaa agagataaaa aggaagaggt agcgaccgat tcaagcgaaa aagcggagaa
    19861 aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca actataatgc
    19921 gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg atgttaagct
    19981 ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa ctaaagatat
    20041 gaaacatgat tttaaccaca aagcagaaac tttcgactcc cctaaaaata tcttcctcgc
    20101 aaacttggta tgtcaagcag tcgagaaaca gattgatatt ttatcagaca aagtaatttt
    20161 agatttcggt ggtggcacgg gtctattagc cttgccccta gccaagcagg ctaagtcagt
    20221 tactcttgta gacatttctg agaaaatgtt ggagcaagct cgtttgaaag tggagcagca
    20281 agcaatcaag aatatccagt ttttggagca agatttaccg aaaaatccct tggagaaaga
    20341 gtttgattgc cttgctgtta gtcgggttct tcatcatatg cctgatttgg atgcggctct
    20401 ctcactgttt catcaacatt tgaaggaaga tgggaaactc atcattgctg attttaccaa
    20461 gacagaagct aatcatcatg gatttgattt agctgaactg gaaaacaagc taattgagca
    20521 tggtttttca tctgtgcata gtcagattct ctatagcgct gaagacctgt ttcaaggaaa
    20581 tcactcagaa ttctttttaa tagtagccca aaaatcactc gcctagtcag ggagtgattt
    20641 ttctataagg atggaaaaaa gaagggaaat ttgataagat aggaatatgg attttgaaaa
    20701 aattgaacaa gcttatacct atttactaga gaatgtccaa gttatccaaa gtgatttggc
    20761 gaccaacttt tatgacgcct tggtggagca aaacagcatc tatctggatg gtgaaactga
    20821 gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt ttagcactac gcaaagaaga
    20881 atggctcaag acctaccagt ttctcttgat gaaggctggg caaacagaac ccttgcaggc
    20941 caatcaccag tttacaccag atgccattgc tttgcttttg gtgtttattg tggaagagtt
    21001 gtttaaagag gaggaaatta ctatcctcga aatgggttct gggatgggaa ttctaggcgc
    21061 tactttcttg acctcgcttg ataaaaaggt ggattacttg ggaatggaaa tggatgattt
    21121 gctgattgat ctggcagcta gcatggcaga tgtaattggt ttgcaggctg gctttgtcca
    21181 aggagatgcc gttcgtccac aaatgctcaa agaaagcgat gtggtcatca gtgacttgcc
    21241 tgttggctat tatcctgatg atgccgttgc gtcgcgccat caagttgctt ctagccaaga
    21301 acatacttac gcccatcact tgctcatgga acaagggctt aagtacctca agtcagacgg
    21361 atacgctatt tttctagctc cgagtaattt gttgaccagt cctcaaagtg atttgttaaa
    21421 agaatggctg aaagaagagg cgagtctggt tgctatgatt agtctgcctg aaaatctctt
    21481 tgctaatgcc aaacaatcta agactatttt tatcttacag aagaaaaatg aaatagcagt
    21541 agagcctttt gtttatccac ttgctagctt gcaagatgca agtgttttaa tgaaatttaa
    21601 agaaaatttt caaaaatgga ctcaaggtac tgaaatataa aatagatttt gttataatag
    21661 ttgaaaacgc ttaaaaaggg gtatcatgtt atgacaaaaa caattgcaat caatgcagga
    21721 agttcaagtt tgaaatggca attatactta atgccagaag aaaaagtgtt agccaaaggt
    21781 ttgattgaac gtatcggttt gaaagattca atttcaactg taaaatttga cggccgttct
    21841 gaacaacaaa ttttggatat tgaaaatcat acacaagccg ttaaaatttt attggatgac
    21901 ttgattcgtt tcgatattat caaggcttat gacgagatta caggtgttgg acatcgtgtt
    21961 gttgctggtg gagaatattt caaagaatca acagttgttg agggagatgt tttagaaaaa
    22021 gttgaagagt tgagtttgtt ggctcctcta cacaacccgg ccaatgcagc aggtgttcgt
    22081 gccttcaagg aattgttgcc agacattacc agtgtagttg tttttgatac ttccttccac
    22141 acaagtatgc cagagaaagc ttatcgctac cctctaccaa caaaatatta cacagaaaac
    22201 aaggttcgta aatacggtgc tcatggtaca agtcaccagt ttgtagcagg agaagctgca
    22261 aaactcttgg gacgtccatt agaagacttg aagttaatta cctgtcatat tggtaacgga
    22321 ggctcaatta cagctgtgaa agccggcaaa tctgtagaca cttctatggg gttcactcct
    22381 cttggtggta ttatgatggg aacgcgtaca ggggatattg atccagctat cattccttat
    22441 ttaatgcaat atacagagga ttttaacaca ccagaagata tcagtcgtgt tcttaaccgt
    22501 gaatcaggtc ttttgggagt ttctgctaat tctagcgata tgcgcgatat agaagcagct
    22561 gtagcagaag ggaatcacga ggctagcttg gcttatgaaa tgtatgttga ccgtatccaa
    22621 aaacatatcg gtcagtactt tgcagtgcta aatggagcag atgccattgt tttcacagca
    22681 ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa tctcagggat ttcgtggttt
    22741 ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta caggagacat ctcaacagag
    22801 gcagctaaaa tccgtgtctt ggttattcca acagatgaag aattagtcat tgcccgtgac
    22861 gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt caatacaagg agttgggaaa
    22921 gttatttttc cagcttcttt ttctgatgaa attgtccaaa accttgctat gattggcttt
    22981 tttgaaaaat atggtataat agtagtaatt taatagatgg agttgagttt tgaagaaaaa
    23041 ctttcgtgta aaaagagaga aagattttaa ggcgattttc aaggagggga caagttttgc
    23101 taatcgcaaa tttgtggtct accaattaga aaaccagaaa aaccattttc gagtaggtct
    23161 atcagttagc aaaaaactgg ggaatgccgt cactagaaat caaattaagc gacggattcg
    23221 gcatattatc cagaatgcaa aagggagtct ggtagaagat gtcgactttg ttgtcattgc
    23281 tcgaaaagga gtcgaaacct tgggatacgc agagatggag aaaaatctac tccatgtatt
    23341 aaaattatca aagatttacc gggaaggaaa tgggagtgaa aaagaaacta aagttgacta
    23401 gtttgctagg actgtctctg ttaatcatga cagcctgtgc gactaatggg gtaactagcg
    23461 atattacagc cgaatcggct gatttttgga gtaaattggt ttacttcttt gcgaaaatca
    23521 ttcgcttttt atcgtttgat attagtatcg gagtggggat tattctcttt acggtcttga
    23581 ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt ggcttctagg aaaatgcagg
    23641 aagctcagcc acgcattaag gcgcttcgag aacaatatcc aggtcgagat atggaaagca
    23701 gaaccaaact agagcaggaa atgcgtaaag tatttaaaga aatgggtgtc agacagtcag
    23761 attctctttg gccgattttg attcagatgc cggttatttt ggccttgttc caagccctat
    23821 caagagttga ctttttaaag acaggtcatt tcttatggat taaccttggt agtgtggata
    23881 caacccttgt tcttccgatt ttagcagcag tattcacctt tttaagtact tggttgtcca
    23941 acaaagcttt gtctgagcga aatggcgcta cgactgcgat gatgtatggg attccagtct
    24001 tgatttttat ctttgcagtt tatgcgccag gtggagtcgc cctatactgg acagtgtcta
    24061 atgcttatca agtcttgcaa acctatttct tgaataatcc attcaagatt atcgcagagc
    24121 gcgaggccgt agtacaggca caaaaagatt tggaaaatag aaaaagaaaa gccaagaaaa
    24181 aggctcagaa aacgaaataa ataaggagga atctggtaat ggtagtattt acaggttcaa
    24241 ctgttgaaga agcaatccag aaaggattga aagaattaga tattccaaga atgaaggctc
    24301 atatcaaagt catttctagg gagaaaaaag gctttcttgg tctatttggt aaaaaaccag
    24361 cccaagtgga tattgaagcg attagtgaaa cgactgttgt caaagcaaat caacaggtag
    24421 taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc tgtgaagacg gttagtgaag
    24481 aaaccgttga ccttggtcat gtggttgatg ctattaaaaa aatagaggaa gaaggtcaag
    24541 gtatttctga tgaagtcaag gctgaaatct taaaacatga aagacatgcc agcactatct
    24601 tagaagaaac tggtcacatt gagattttaa atgaacttca aatcgaggaa gcgatgaggg
    24661 aagaagcagg cgctgatgac cttgaaactg agcaagatca aactgaaaat caagacttga
    24721 aagagatggg cttgaaggtc gagcaaagtt atgatattgc ccaggtggct acggatgtga
    24781 ctgcctatgt tcaagcgatt gtggatgaca tggatgttga agctacactt tcaaatgatt
    24841 ataaccgtcg tagcatcaat ctacaaattg acaccaacga accaggtcgt attatcggct
    24901 accatggtaa agtcttgaag gccttgcaac tgttggctca aaattatctt tacaaccgct
    24961 attccaaaac cttctacgtt acaatcaatg tcaatgatta tgtcgaacac cgtgcagaag
    25021 tcttgcagac ctatgcgcaa aaattggcga ttcgtgtttt agaagaagga cgtagtcatc
    25081 aaacagatcc aatgtcgaat agtgaacgca agattatcca ccgtattatt tcacgtatgg
    25141 atggcgtgac cagttactct gaaggtgatg agccaaatcg ctatgtcgtt gtagatacag
    25201 aataagtaaa atcagggttg acctgatttt ttgctagcta gaggaggtta aactgatgtt
    25261 gaataagata agagactatt tagactttgc tggtttgcag taccgtaatc ctgataaagc
    25321 gggagcagag cgagagaaga tgctggcatt ccgccacaaa ggacaagagg cccgaaaggc
    25381 ttttacagaa ctggccaaag cctttcaagc aagccatcca gaatggcaac tccaacagac
    25441 tagtcagtgg atgaatcagg cccagcgttt gagaccacat ttttgggttt atctacagag
    25501 agacggacaa gtgacagaac ctatgatggc cttacgtttg tatgggacat ctactgactt
    25561 tggaatttct ttggaagtca gtttcatcga acgtaagaag gatgagcaaa cactgggcaa
    25621 gcaggccaaa gttttagaca ttccaaccgt taaagggatt tattatctaa cctactctaa
    25681 tggtcaaagt caacggtggg aggcgaatga agaaaagcgt cgtactttac gcgagaaggt
    25741 gagaagtcaa gaagttcgaa aagttttagt gaaggtagat gttcctatga cagaaaattc
    25801 gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat tctaaaattc ttccctatta
    25861 tctagctacg agaaaataag ataatttgta aaacatcata aatcatacag tccaagagtg
    25921 aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat ataataaact
    25981 tacaaaaaca attcaaaagg agaacaatta tggaagtcgt ttcaagtgtt ctaaattggt
    26041 tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg ttgataggat
    26101 atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa gcaacagtag
    26161 ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt ccaatcttag
    26221 cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac tttggacttg
    26281 ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact gcaactacag
    26341 ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag attacgaagg
    26401 taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca gtatctctta
    26461 tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg attggtatca
    26521 tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact caacgcttga
    26581 ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg tttgtagata
    26641 aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa ttacctaagt
    26701 tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc gtattcttcg
    26761 gggccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc atcacttcag
    26821 gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa acagccttta
    26881 ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta tctgagttga
    26941 caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca gcggttgacg
    27001 ttgcagcttc ttatggattt ggttctccaa atgctgtctt gtcaggattt acctttggtt
    27061 tgattggtca attgattaca attgtcttgc tcatcgtctt taaaaatccg attcttatta
    27121 ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac gctgataaac
    27181 gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt caagttgctc
    27241 taggagctct ttgtgtggcc cttctcgatt tggcatctta tggtggctac catggaaata
    27301 tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt ggtattgttg
    27361 gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt gccaaagcaa
    27421 aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat ctagaaaagg
    27481 agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc atcaatggtt
    27541 atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaacagattt tacagtcaat
    27601 tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt aatcgcttct
    27661 cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg acttgataac
    27721 ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta aaaggttgga
    27781 gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctcttt aaataaagga
    27841 ggcagatatg aatttaaaac aagctttaat tgacaatgac tcgatccgac taggtttaga
    27901 ggctaacaat tggaaagaag cagtcaaggt agcagtagat cccttaattg aaagtggggc
    27961 aattttgcca gagtattacg atgctatcat tgaatcgact gaagagtatg ggctttacta
    28021 tatcttgatg ccaggtatgg ctatgcccca cgctagacct gaagctggtg tgcaaagtga
    28081 tgccttttca ttgattacct tacaaaatcc tgttgtattt tcagatggga aagaggtatc
    28141 tgttttgttg gcactagcag caacaagctc aaaaattcac acaagtgtag ccattccaca
    28201 aattattgcc ctgtttgaat tagaagattc tattgcacgt ttacaggctt gccagactaa
    28261 agaagatgtc ttggctatga ttgaagaatc taaggatagc ccttatctcg aaggattgga
    28321 tttggaaagt tagaaagagg aataaagaaa tgacaaaaag aatacctaat ttacaagttg
    28381 cattagacca ttcagacttg caaggagcga ttaaagcagc tgtttctgtt ggtcaggaag
    28441 tagatattat cgaagctgga actgtttgct tgcttcaagt tggaagtgaa ctggctgaag
    28501 tcttgcgtag ccttttccca gataagatta ttgtggcaga cacaaaatgt gctgatgctg
    28561 gtggaacagt tgctaaaaat aatgcggttc gtggagcaga ctggatgact tgtatctgtt
    28621 gtgcaaccat ccctactatg gaagcagctc taaaggctat caagactgaa cgaggagaac
    28681 gaggcgaaat ccagatcgag ctttatggcg attggacttt tgaacaagct cagctttggc
    28741 tagatgcagg tatctcacaa gctatttatc accaatctcg tgatgctctt cttgctggtg
    28801 aaacttgggg tgaaaaagac cttaataagg ttaaaaaact cattgacatg ggcttccgtg
    28861 tatctgtaac aggtggtcta gatgtagata ctctcaaact ctttgaaggt gttgatgtct
    28921 ttacctttat cgcaggtcgt ggaattacag aggctgcgga tccagcagga gcagcgcgtg
    28981 ccttcaagga tgaaatcaaa cgaatttggg ggtaaatcat ggtacgtcca attggaattt
    29041 atgaaaaggc aaccccaaca cactttactt ggctagaacg tttaaatttt gccaaggagt
    29101 taggctttga ttttgtcgag atgtctattg acgaacgtga cgagcgttta gcaagacttg
    29161 actggagtaa ggaagaacgc ttggaagttg tcaaagcaat ctatgaaact ggtgttcgta
    29221 ttccttctat ctgtttttca ggccatcgtc gctacccatt gggttcaaaa gatccagttc
    29281 tagaggaaaa atctctagaa ctcatgaaaa aatgtatcga attagctcaa gacttgggag
    29341 ttcgtacgat tcaattagct ggttacgatg tttactatga ggaaaagtca ccccagacac
    29401 gccaacgttt tatcaaaaat ttgagaaaag cctgtgactg ggctgaagaa gctcaggtgg
    29461 tacttgctat tgaaattatg gatgatcctt tcatcaatag catcgaaaaa tatttggcta
    29521 tagaaaaaga gattgactct cccttcctct ttgtatatcc agatattggt aatgtgtctg
    29581 catggcataa tgatatctat agtgagtttt atcttggtca tcatgccatc gcagctctcc
    29641 atctcaagga tacttatgca gtgacagaaa gttcaaaggg ccagttccga gatgtacctt
    29701 tcgggcaagg ttgtgtcaaa tgggaagaag ctttcgatat tttaaaggaa accaattata
    29761 atggaccttt cctaatcgaa atgtggtctg aaaattgtga aacagtagaa gaaacacgcg
    29821 cagccattca agaggcgcaa gcttttctct atccactcat taagaaagca ggtttgatgt
    29881 aagatgaatc aagtaatcaa tgctatgcgt aaacgagtct gtgatgccaa tcaatcattg
    29941 ccaaaacatg gacttgtcaa atttacctgg gggaatgtat ctgaagttaa tcgcgaactc
    30001 ggtgtcattg ttatcaaacc atcaggcgtg gattatgacg aattgacacc tgaaaacatg
    30061 gtagtgactg atctagatgg taagatccta gaaggggatt taagaccatc ttccgacctc
    30121 ccaactcatg tgcaattata taaggcttgg tcagaaattg gtagtgtggt tcacacccat
    30181 tcgacagaag ctgttggttg ggctcaggca ggtcgtgata ttcctttcta cggaacaacc
    30241 catgcagatt atttctacgg ttcaatccct tgcgcccgta gtttgaccaa ggacgaagta
    30301 gaagtggcct atgaaaaaga tactggcctg gttatcgtag aagagtttga acatcgcgga
    30361 cttaacccgg ttgaagtacc aggaattgtt gtacgcaatc acggtccatt cacctggggc
    30421 aaaaatccag agaatgctgt ttatcactct gtcgtactag aggaagtatc aaagatgaat
    30481 cgctttacag aacaaatcaa tccaagagtt ggacctgctc cccagtacat actagaaaaa
    30541 cactaccaac gtaaacatgg accaaatgct tattatggtc aaaagtaaga acgatgaagg
    30601 aggagaaaaa gataaattta gctcctcttt ttacatttga tttttattga gagtaaagtt
    30661 ggaattgaag taattttaaa agatttttta gaaatagcgc ttgatatata tatggtaaaa
    30721 taaaaagaat tgctgtgata tcaatagatt tgggggattt tttaatatgg tactggataa
    30781 ggcaagttgt gatttgcttc aatatttgat ggatcaagaa acgtccaaaa cgattatggc
    30841 gatttcgaaa gatttgaaag agtcaagaag gaaaatttat tatcacattg acaaaatcaa
    30901 tgctgctctg gttgacgagg cgcttcacat cattagtatt ccacgaattg gtattcactt
    30961 aacggaagag cagagagatg cttgttgtaa actattatcg gaagtagatt cgtacgatta
    31021 tatcatgagt gcgcatgaac gtatgatgat aatgttacta tggataggta tttctaaaga
    31081 acgtattacg attgaaaaat tgatagagtt aacagaggta tctaggaata ctgttctcaa
    31141 tgatttgaat agtattcgtt atcaactaac tttggaacaa tatcaggtga tcttgcaagt
    31201 gagcaagtca cagggatacc accttcatgc ccaccctctt aataaaattc agtatcttca
    31261 atcgcttcta tatcatattt ttatggaaga aaatgccact tttgtatcta ttttagaaga
    31321 taagatgaaa gagaggttag atgatgagtg tttgctttct gttgaaatga accaattttt
    31381 taaggaacag gttcctttag ttgaacaaga tttagggaag aaaataaacc atcatgaaat
    31441 aacttttatg ttgcaggttc taccttattt gctgttaagc tgtcataatg ttgaacagta
    31501 tcaagaaaga catcaggata tagagaaaga attttctttg ataagaaaaa gaatagagta
    31561 tcaggtgtct aagaaattag gagaacggtt gtttcaaaag tttgaaattt ctttgtcagg
    31621 acttgaagtt tctcttgtag ctgttctcct cctctcctat cgtaaggatt tggatattca
    31681 tgcagaaagt gatgattttc ggcaattaaa acttgcttta gaagaattta tctggtattt
    31741 tgaatcacaa atccgaatgg agattgagaa caaggatgat ttgttacgaa atttgatgat
    31801 ccactgtaaa gccttgttat ttagaaagac ttacggtatt ttttctaaaa atcctctaac
    31861 aaaacaaatt cgatccaagt atggagaatt atttttagtc actagaaaat ctgcggaaat
    31921 tttagaagga gcatggttta ttcggctaac agacgatgat attgcctatt tgacgattca
    31981 tattggagga tttttaaagt atacaccatc gtctcaaaaa aatatgaaaa aagtttatct
    32041 cgtttgtgat gaaggtgttg cggtttcgag acttttgctg aaacaatgca aactttattt
    32101 tccaaatgag caaattgaca ctgtatttac aacagaacaa tttaagagtg tggaagatat
    32161 tgcacaagtt gatgtagtga ttactactaa tgatgatttg gatagcagat ttccgatttt
    32221 aagggttaat cctatccttg aagcagaaga tattttgaaa atgctagact atcttaaaca
    32281 caatatattt cgtaataaga gcaaaagttt cagtgaaaat ctttctagtc ttatttcgtc
    32341 ttatattgta gacagcaagt tggctagtaa gttccaagaa gaggttcaaa cacttataaa
    32401 taaagaaata gtagttcaag cttttttgga agatatttga aggacagtcc aatgatgaac
    32461 acaaacctgt gtttttcttg gtctttttta gtgttttgaa gggtggtata ctaatctcaa
    32521 agataacaat tatatccaaa ggaggcaaca tatgccaaac gtcaaagaaa ttacaagaga
    32581 gtcatggatt ttagccactt tcccagagtg gggaacatgg ttgaacgaag aaatcgaaga
    32641 agaagtcgta cctgaaggca actttgccat gtggtggcta ggcaactgtg gtacttggat
    32701 taagacacca gctggtgcta acgttgtcat ggacctttgg tcaaaccgtg gaaaatcaac
    32761 caaaaaagtg aaagatatgg ttcgtgggca ccaaatggca aatatggcag gtgttcgtaa
    32821 gttgcaacca aacttgcgtg ttcagccaat ggttatcgat ccatttgcta tcaacgaact
    32881 agactattac ttagtttcac acttccacag tgatcatatc gacccataca cagctgcagc
    32941 aattctcaac aatcctaagt tagagcatgt taagtttatc ggtccttacc actgtggacg
    33001 aatctgggaa ggatggggtg ttccaaaaga acgtatcatc gttgttaaac caggtgacac
    33061 tatcgaatta aaagatatga agattcatgc agtagaatca tttgaccgta cttgcttggt
    33121 aactctccca gtgaacggtg ctgatgagac aggcggtgaa cttgctggct tggctgttac
    33181 agatgaagaa atggctcaaa aggctgttaa ctatatcttt gaaacaccag gtggaaccat
    33241 ctatcatggt gcagattctc acttctcaaa ctattttgca aaacatggta aagactttaa
    33301 aattgatgtt gctttgaata actatggtga aaatccggta ggtatccaag acaaaatgac
    33361 atctatcgat cttcttcgta tggcagaaaa tctgcgtacc aaagtcatta tcccagttca
    33421 ctatgatatc tggtctaact tcatggcttc tactaatgag attctagaac tttggaaaat
    33481 gcgaaaagat cgcttgcaat acgatttcca tccatttatc tgggaagttg gcggtaagta
    33541 cacttatcct caagatcaac acttagtaga ataccatcat ccacgtggtt ttgatgattg
    33601 ttttgaacaa gactctaaca ttcaatttaa agctttgcta taatataaaa atattctttg
    33661 gaggttatcc gtatgttgca tgatacggat aattttcata taatagtaaa atagaatgtg
    33721 tgattcaata atcacctcaa atagaaagga aattctatgt caaatctatc tgttaatgca
    33781 attcgttttc taggtattga cgccattaat aaagccaact caggtcatcc aggtgtggtt
    33841 atgggagcgg ctccgatggc ttacagcctc tttacaaaac aacttcatat caatccagct
    33901 caaccaaatt ggattaaccg cgaccgcttt attctttcag caggtcatgg ttcaatgctc
    33961 ctttatgctc ttcttcacct ttctggtttt gaagatgtca gcatggatga gattaagagt
    34021 ttccgtcaat ggggttcaaa aacaccaggt cacccagaat ttggtcatac ggcagggatt
    34081 gatgctacga caggtcctct agggcaaggg atttcaactg ctactggttt tgcccaagca
    34141 gaacgtttct tggcagccaa atataaccgt gaaggctaca atatctttga ccactatact
    34201 tacgttatct gtggagacgg agacttgatg gaaggtgtct caagcgaggc agcttcatac
    34261 gcaggtttgc aaaaacttga taagttggtt gttctttatg attcaaatga tatcaacttg
    34321 gatggtgaga caaaggattc ctttacagaa agtgttcgtg accgttacaa tgcctacggt
    34381 tggcatactg ccttggttga aaatggaaca gacttggaag ccatccatgc tgctatcgaa
    34441 acagcaaaag cttcaggcaa gccatcttta attgaagtga agacggttat tggatatggt
    34501 tctccaaaca aacaaggaac taatgctgta cacggcgccc ctcttggagc agatgaaacc
    34561 gcatcaactc gccaagccct cggttgggac tacgaaccat ttgaaattcc agaacaagta
    34621 tatgctgatt tcaaagaaca tgttgcagac cgtggcgcat cagcttatca agcttggact
    34681 aaattagttg cagattataa agaagctcat ccagaactgg ctgcagaagt agaagccatc
    34741 atcgacggac gtgatccagt cgaagtgact ccagcagact tcccagcttt agaaaatggt
    34801 ttttctcaag caactcgtaa ttcaagtcaa gatgccttga atgttgtggc agctaaatta
    34861 ccaaccttcc taggtggatc agctgacctt gctcactcaa acatgactta tatcaagacg
    34921 gatggacttc aagacgatac caatcgcttg aatcgtaaca ttcagtttgg tgttcgtgaa
    34981 tttgcaatgg gaacaatctt gaacgggatg gcccttcatg gtggacttcg tgtatacggt
    35041 ggaactttct tcgtcttctc tgactatgtg aaggcagctg tccgcttgtc agccttacaa
    35101 ggacttcctg tgacttatgt ctttacccat gattcaatcg cagttgggga agatggtccg
    35161 actcacgaac cagttgagca tttagcaggt cttcgtgcta tgccaaatct aaatgttttc
    35221 cgtccagcag atgcgcgtga aacgcaagca gcttggtacc ttgcagtgac aagtgagaaa
    35281 acaccaactg cccttgtctt gacacgtcaa aacttgactg ttgaagatgg aacagacttc
    35341 gacaaggttg ctaaaggtgc ttatgttgta tatgaaaatg cagccgactt tgataccatc
    35401 ttgattgcga caggttcaga ggttaatctt gctgtctcag ctgctaaaga attggctagt
    35461 caaggcgaaa aaatccgcgt agtcagcatg ccatctacag atgtctttga taaacaagat
    35521 gcagcttaca aggaagagat tcttccaaat gcagtccgcc gtcgtgttgc agtcgaaatg
    35581 ggtgcaagtc aaaactggta caaatatgtt ggtctcgatg gtgccgttct aggtattgat
    35641 accttcggag cctctgcccc agcaccaaaa gtattggcag aatatggctt tactgtagaa
    35701 aatcttgtaa aaattgttcg aaacttgaaa taatcctaaa aatcagggcg taagctctgg
    35761 tttttcttac cagaaaagta aggtacaatc ttgtaaaagt agctgaaatt tgatatagta
    35821 gtcctatgta aaagacaaag gagaaaacaa tgaatccaaa tattactttt ttaatcatgc
    35881 ttgtaggtat gatggccttg atgttcttta tgcaacgttc tcaaaagaaa caagctcaaa
    35941 agcgtatgga aagcttaaat aaactacaaa aaggctatga agtgattaca atcggtggac
    36001 tttatggaac agtcgatgaa gtagatacgg agaagggaac aatagttctt gacgtagatg
    36061 gagtttactt gacttttgaa ctagctgcta tcaagacagt attaccgctg aaagaaacag
    36121 cttcactaga aggcgcaatt gaaaaataag acgggatcac gaactcccgt ttttctataa
    36181 aagaaaggaa atgggatgaa aaaattagtc tttgtctgtc tgggaaatat ttgccgtagc
    36241 cctatggccg agtttgttat gaaatcaatg acagataact acgaaatcca aagtcgagca
    36301 acttcctctt gggaacatgg caatccgatt cataagggga ctcagggaat ttttcaagag
    36361 tatgagattc cttatgacaa gaacaagaca tcgcttcaga ttagtaagga agattttgaa
    36421 gcctttgatt atattatcgg aatggacgct tcaaatattt ctgacttatg tcagatgtgt
    36481 ccagtagact gtcaagataa gatttactca ttttcatctg aaagtgttcc agacccttgg
    36541 tatacaggag attttgaaga aacctatcga cgtgttcaag agggctgtca agcttggtta
    36601 gaacgtttag aaaaggagag ttaaggtgga aaatcttacg aatttttacg aaaagtatcg
    36661 tgtctatctg actcgtccac gtttagagct tttggcagta gttaccattg ttttttgtgc
    36721 tgtactcgtc ttttttctaa atattccagg aaaaggtgtc ttaaaactcg ataatggaac
    36781 gattgtttat gatggcagtc ttgtccgtgg taaaatgaat ggccaaggta ccattacctt
    36841 ccaaaatgga gaccaatata caggtggctt caacaatgga gccttcaacg gaaaaggtac
    36901 ctttcaatct aaagaaggct ggacctacga aggtgatttt gtaaatggtc aggctgaagg
    36961 aaaagggaaa ctaacaacag aacaagaagt cgtttatgaa ggaactttta aacaaggcgt
    37021 ttttcaacaa aaataaagcc tccttatcaa aggaggtatt attagaatca caaggtaagc
    37081 gcttacctgt aaatcccttt ctttccaaat ccctcttcca agcaagtttg tgaaataaaa
    37141 aatatttgaa ataaatttca caaacttcaa agataaaact tgataagaaa agaaaatgag
    37201 aaaagtttca caagagttta aaaattcttt gtgaaatgtt tatgaaactg tttacaaagt
    37261 tgaaataatg cgttataata aacttgtgaa aaaattaaca aaggatatcg ttccttgaaa
    37321 gctatggagg aaaatatggc tgataaaaaa actgtgacac cagaggaaaa gaaactcgtt
    37381 gctgaaaaac acgtagatga gttggttcaa aaagctctag ttgcccttga agaaatgcgt
    37441 aaattggatc aagaacaagt tgactacatc gttgccaaag catcagtagc agctttggat
    37501 gcccacggag aattggcttt acatgccttt gaagaaacag gacgtggtgt atttgaagac
    37561 aaagcaacta agaacttgtt tgcttgtgaa cacgtagtaa acaatatgcg ccacactaag
    37621 acagttggcg ttatcgaaga agacgatgta acaggattga ctcttattgc tgaaccagtt
    37681 ggtgttgttt gtggtattac tccaacaaca aacccaacat caacagcaat cttcaaatca
    37741 ttgatttcat tgaagacacg taacccaatc gtctttgcct tccatccatc agcacaagaa
    37801 tcatctgctc atgcagctcg tatcgtccgc gatgcagcta tcgcagctgg tgctcctgaa
    37861 aactgtgtgc aatggattac tcaaccatct atggaagcaa caagtgccct tatgaaccac
    37921 gaaggtgttg cgacaatcct tgcaacaggt ggtaatgcca tggttaaggc ggcttattca
    37981 tgtggtaaac cagctcttgg ggtaggtgcc ggaaacgttc cagcttatgt tgaaaaatca
    38041 gcaaacattc gtcaagcagc acacgatatc gtcatgtcta aatcatttga taacggtatg
    38101 gtctgtgcat ctgaacaagc agttatcatt gataaagaaa tttacgatga atttgtagca
    38161 gagttcaaat cttaccacac ttactttgta aacaaaaaag aaaaagctct tcttgaagag
    38221 ttctgcttcg gcgtcaaagc aaacagcaaa aactgtgctg gtgcaaaatt gaacgctgac
    38281 atcgttggta aaccagcaac ttggattgca gaacaagcag gatttacagt tccagaagga
    38341 acaaacattc ttgctgcaga atgtaaagaa gttggcgaaa atgagccatt gactcgtgaa
    38401 aaattgtcac cagttattgc agttttgaaa tctgaaagcc gtgaagatgg tattactaag
    38461 gctcgtcaaa tggttgaatt taacggtctt ggacactcag cagctatcca cacagctgac
    38521 gaagaattga ctaaagaatt tggtaaagct gttaaagcta ttcgtgttat ctgtaactca
    38581 ccttctactt ttggtggtat cggggacgtt tacaatgcct tcttgccatc attgacactt
    38641 ggatgtggtt cttacggacg caactcagtt ggggataacg ttagtgccat taacctcttg
    38701 aatatcaaaa aagtcggaag acggagaaat aacatgcaat ggatgaaact tccttcaaaa
    38761 acatactttg aacgtgattc aattcaatac cttcaaaaat gtcgtgacgt tgaacgtgtc
    38821 atgatcgtta ctgaccatgc catggtagag cttggtttcc ttgatcgtat catcgaacaa
    38881 ctggaccttc gtcgcaataa ggttgtttac caaatctttg cggatgtaga accggatcca
    38941 gatatcacaa ctgtaaaccg tggtactgag attatgcgtg ccttcaaacc agataccatc
    39001 atcgcactcg gtggtgggtc tccaatggat gctgccaaag taatgtggct cttctacgag
    39061 caaccagaag tggacttccg tgaccttgtc caaaaattca tggatatccg taaacgtgcc
    39121 ttcaagttcc cattgcttgg taagaagact aaattcatcg cgattccaac tacatctggt
    39181 acaggatctg aagtaacacc atttgccgtt atctctgata aagcaaacaa ccgtaaatac
    39241 ccaatcgctg actactcatt gacaccaact gtggcaatcg tagatcctgc tttggtattg
    39301 acagttccag gatttgttgc tgctgatact ggtatggacg tattgactca cgcgacagaa
    39361 gcatacgtat cacaaatggc tagtgactac actgatggtt tagcacttca agccattaaa
    39421 ttggtctttg aaaatctcga aagctcagtt aagaatgcag acttccactc acgtgagaaa
    39481 atgcataacg cttcaacaat cgctggtatg gcctttgcca atgccttcct aggtatttct
    39541 cactcaatgg cccataagat tggtgcgcaa ttccacacaa tccacggtcg tacaaatgct
    39601 atcttgcttc catacgttat ccgttacaac ggtacacgtc cagctaagac agcaacatgg
    39661 cctaagtaca actactaccg tgcagatgaa aaataccaag atatcgcacg catgcttgga
    39721 cttccagctt ctactccaga agaaggggtt gaatcttacg caaaagctgt ctacgaactc
    39781 ggtgaacgta ttgggatcca aatgaatttt agagaccaag gaattgacga aaaagaatgg
    39841 aaagaacatt ctcgtgaatt agccttcctg gcttatgaag accaatgttc accagctaac
    39901 ccacgtcttc caatggtaga ccatatgcaa gaaatcatcg aagatgcata ctatggctac
    39961 aaagaaagac caggacgccg taaataattg tttatcagtc tagaagcaag acaaaaactc
    40021 aatttgaggg aaagatccag taatttttct atgataaaag gcatcctatc aaggtttttg
    40081 aacacctgat aggatgcctt tttatgatat tgaggccttt ttgccctttt tgaaaaacta
    40141 gaatagaaac aaaatatata atagattgaa actggaatag tacacttctg cttctaaaac
    40201 attgttagaa ttcgatttga ctgtcctgat cgatttgtcc tattcctatt tcattttatt
    40261 atataaaaaa tat
//
LOCUS       DBERCW010000017        39625 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.017, whole genome shotgun sequence.
ACCESSION   DBERCW010000017 DBERCW010000000
VERSION     DBERCW010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.017"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..783)
                     /locus_tag="ACL72M_001086"
     CDS             complement(<1..783)
                     /locus_tag="ACL72M_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716223.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPQVVEKSSLE
                     KKYEEAKAKADTAKKDYETAKKKAEDAQKKYDEDQKKTEEKAKKAEEAAKEVDDASLA
                     VQKAYVEQRKAQEEKNKHSGNPEYAKKLAEADKKITEETTKLTDAQTKFQSVQAMVVP
                     EPEQLAETKKKAEEAKAEEKVAKRKYDYATLKVVLAKKEVEAKELEIEKLQYEISTLE
                     QEVATAQHQVDNLKKLLAGADPDDGTEVIEAKLKKGEAELNAK"
     gene            complement(1069..1608)
                     /locus_tag="ACL72M_001087"
     CDS             complement(1069..1608)
                     /locus_tag="ACL72M_001087"
                     /inference="COORDINATES: protein motif:HMM:NF037419.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HGS0716224.1"
                     /translation="MLFYFEKIWSLSLKLLDCILDYQERFNRKACQVSTNYKYLETFK
                     VNFCLTDLHHLFGLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLYEFI
                     GDIFYFKITSCCIVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFT
                     SAKKYAKVRKTDVKEMKWL"
     gene            complement(2031..2228)
                     /locus_tag="ACL72M_001088"
     CDS             complement(2031..2228)
                     /locus_tag="ACL72M_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716225.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            complement(2707..3435)
                     /locus_tag="ACL72M_001089"
     CDS             complement(2707..3435)
                     /locus_tag="ACL72M_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716226.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            complement(3432..3764)
                     /locus_tag="ACL72M_001090"
     CDS             complement(3432..3764)
                     /locus_tag="ACL72M_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS0716227.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(3820..4722)
                     /locus_tag="ACL72M_001091"
     CDS             complement(3820..4722)
                     /locus_tag="ACL72M_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716228.1"
                     /translation="MMRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(4728..5045)
                     /locus_tag="ACL72M_001092"
     CDS             complement(4728..5045)
                     /locus_tag="ACL72M_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716229.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGDWNTFKNNIKGLARASSGFRF
                     AARETGLWAAIWSTRVYSYTYVVSAFAPILGSVAAVNAALAVIGGISVAGITYALWTR
                     KFY"
     gene            complement(5190..6542)
                     /locus_tag="ACL72M_001093"
     CDS             complement(5190..6542)
                     /locus_tag="ACL72M_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HGS0716230.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADNKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLLPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(6539..7006)
                     /locus_tag="ACL72M_001094"
     CDS             complement(6539..7006)
                     /locus_tag="ACL72M_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS0716231.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(6999..9218)
                     /locus_tag="ACL72M_001095"
     CDS             complement(6999..9218)
                     /locus_tag="ACL72M_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGS0716232.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIMEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            9684..10547
                     /locus_tag="ACL72M_001096"
     CDS             9684..10547
                     /locus_tag="ACL72M_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0716233.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            complement(10836..12227)
                     /gene="argH"
                     /locus_tag="ACL72M_001097"
     CDS             complement(10836..12227)
                     /gene="argH"
                     /locus_tag="ACL72M_001097"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS0716234.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAYHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(12256..13453)
                     /locus_tag="ACL72M_001098"
                     /pseudo
     CDS             complement(12256..13453)
                     /locus_tag="ACL72M_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(13470..14276)
                     /locus_tag="ACL72M_001099"
     CDS             complement(13470..14276)
                     /locus_tag="ACL72M_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0716235.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLVTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYSVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(14483..15124)
                     /locus_tag="ACL72M_001100"
     CDS             complement(14483..15124)
                     /locus_tag="ACL72M_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716236.1"
                     /translation="MIELENITKTIGGKVILDRLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(15121..17229)
                     /locus_tag="ACL72M_001101"
     CDS             complement(15121..17229)
                     /locus_tag="ACL72M_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS0716237.1"
                     /translation="MKKISHLCMLLLLLCTTFFVLNVNVTREIVRIQEMGKTTYSFDL
                     YLKDVTKPTETILQFFEEVASQDKVSIIKVDNGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLFSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     ALASRMEKRSLVELLKGGIL"
     gene            complement(17284..17565)
                     /locus_tag="ACL72M_001102"
     CDS             complement(17284..17565)
                     /locus_tag="ACL72M_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS0716238.1"
                     /translation="MNHEKISVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFGY
                     SDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            17977..18303
                     /locus_tag="ACL72M_001103"
                     /pseudo
     CDS             17977..18303
                     /locus_tag="ACL72M_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(18355..18942)
                     /locus_tag="ACL72M_001104"
     CDS             complement(18355..18942)
                     /locus_tag="ACL72M_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS0716239.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            19184..19855
                     /gene="sdaAB"
                     /locus_tag="ACL72M_001105"
     CDS             19184..19855
                     /gene="sdaAB"
                     /locus_tag="ACL72M_001105"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGS0716240.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            19864..20736
                     /gene="sdaAA"
                     /locus_tag="ACL72M_001106"
     CDS             19864..20736
                     /gene="sdaAA"
                     /locus_tag="ACL72M_001106"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGS0716241.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            20758..21390
                     /locus_tag="ACL72M_001107"
     CDS             20758..21390
                     /locus_tag="ACL72M_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0716242.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(21696..23546)
                     /locus_tag="ACL72M_001108"
     CDS             complement(21696..23546)
                     /locus_tag="ACL72M_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGS0716243.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(23588..24745)
                     /locus_tag="ACL72M_001109"
     CDS             complement(23588..24745)
                     /locus_tag="ACL72M_001109"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0716244.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENVEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            24803..25969
                     /locus_tag="ACL72M_001110"
     CDS             24803..25969
                     /locus_tag="ACL72M_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGS0716245.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            26108..26434
                     /locus_tag="ACL72M_001111"
     CDS             26108..26434
                     /locus_tag="ACL72M_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS0716246.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            26421..27014
                     /locus_tag="ACL72M_001112"
     CDS             26421..27014
                     /locus_tag="ACL72M_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGS0716247.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            27007..27918
                     /locus_tag="ACL72M_001113"
     CDS             27007..27918
                     /locus_tag="ACL72M_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGS0716248.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            27981..29045
                     /locus_tag="ACL72M_001114"
     CDS             27981..29045
                     /locus_tag="ACL72M_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGS0716249.1"
                     /translation="MKQEWFESNNFVKTTSKNKPEEQAQEVADKAEETIADFDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(29117..29977)
                     /locus_tag="ACL72M_001115"
     CDS             complement(29117..29977)
                     /locus_tag="ACL72M_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGS0716250.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDDSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILV
                     QDFKTLAQEK"
     gene            complement(30099..31085)
                     /locus_tag="ACL72M_001116"
     CDS             complement(30099..31085)
                     /locus_tag="ACL72M_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGS0716251.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(31357..32832)
                     /locus_tag="ACL72M_001117"
     CDS             complement(31357..32832)
                     /locus_tag="ACL72M_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0716252.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(33090..34013)
                     /locus_tag="ACL72M_001118"
     CDS             complement(33090..34013)
                     /locus_tag="ACL72M_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0716253.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(34027..34956)
                     /locus_tag="ACL72M_001119"
     CDS             complement(34027..34956)
                     /locus_tag="ACL72M_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716254.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(35275..35496)
                     /locus_tag="ACL72M_001120"
     CDS             complement(35275..35496)
                     /locus_tag="ACL72M_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716255.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(35450..35710)
                     /locus_tag="ACL72M_001121"
     CDS             complement(35450..35710)
                     /locus_tag="ACL72M_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716256.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(36136..36291)
                     /locus_tag="ACL72M_001122"
                     /pseudo
     CDS             complement(36136..36291)
                     /locus_tag="ACL72M_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            complement(36477..37088)
                     /gene="rpsD"
                     /locus_tag="ACL72M_001123"
     CDS             complement(36477..37088)
                     /gene="rpsD"
                     /locus_tag="ACL72M_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGS0716257.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(37283..38335)
                     /locus_tag="ACL72M_001124"
     CDS             complement(37283..38335)
                     /locus_tag="ACL72M_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0716258.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(38332..39030)
                     /locus_tag="ACL72M_001125"
     CDS             complement(38332..39030)
                     /locus_tag="ACL72M_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0716259.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGCETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(39197..>39625)
                     /locus_tag="ACL72M_001126"
     CDS             complement(39197..>39625)
                     /locus_tag="ACL72M_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HGS0716260.1"
                     /translation="TQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANG
                     SLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSED
                     KAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT        12112 a         8381 c         6750 g        12382 t
ORIGIN      
        1 tttagcgttt agctcagctt ctcctttttt taatttagct tctataactt ctgtgccatc
       61 atcaggatcc gcaccagcaa gaagtttttt caaattatct acttgatgtt gagcagtagc
      121 aacttcttgt tccaaagtag aaatttcata ttgaagtttt tcaatttcaa gttccttagc
      181 ctctacttct ttcttcgcta gtactacctt tagagttgca taatcatatt ttctcttagc
      241 tactttttct tctgctttag cttcttctgc ttttttctta gtctcagcca actgctctgg
      301 ctcaggaact accattgctt gaacagattg aaattttgtc tgagcatcgg ttagtttagt
      361 cgtctcctca gttatttttt tatctgcttc tgctaatttt ttagcgtact ctggatttcc
      421 tgaatgttta tttttttctt cttgtgcttt tctttgttcc acataagctt tttgcaccgc
      481 taaactagca tcatctactt ccttagcagc ttcttctgct tttttcgctt tctcttcagt
      541 tttcttctga tcctcatcat atttcttctg agcgtcttct gctttctttt tagccgtttc
      601 gtaatctttc ttggcagtat cagcttttgc ttttgcttcc tcatatttct tctctaatga
      661 agatttttcg acaacttgtg gagcttcttc tgctcttaca aaagtaggct gagacgtaac
      721 aaaaccagcc cctaagatag cgacgctggc tagacttgtt aaaatcattt ttttcttatt
      781 catctaaatt tacctctttt ctgatagtca tttttagact atacttatat taagtatact
      841 ccccccgtaa atatttgtca aatgttttat attacatttt tattacaaat ttctatatca
      901 taagcttcta ctccaaaaag ataaagacac tacttttgcc cttttcgatt ctctttttaa
      961 acatagcatc atcttccttc attcctataa aaacatttcc gatgagagag cttgtttttt
     1021 aatttcgtta aacaacaaaa aacgcaagct taagcctgcg gacaatcttt atagccattt
     1081 catttctttc acatctgttt tacgaacttt agcatatttc ttagcgcttg taaaatgtag
     1141 agtaactggt ttaaatactc cgcttttgtc tcttcgtaaa cctaaaactg cggatctttt
     1201 atttttatcc tcaaaaaata tgacgtccaa tttcatagta tttttagata aatccttagc
     1261 tacgatgcaa caacttgtta ttttaaaata gaaaatatca cctataaact catataaaga
     1321 tatcctttcg attacatcat tgtacaatag gatatttcta aaatcttcta aaataaaaac
     1381 accagcttga atagcaggtt ttgtttgact agcataatct cgtgtgattt tgtgtaagcc
     1441 aaataaatga tgtaaatcag tcaggcaaaa attcactttg aaagtctcta aatacttata
     1501 attcgttgat acttgacatg cttttctatt gaatctttct tgataatcca aaatacaatc
     1561 aagtaatttc aacgacaaac tccatatttt ctcaaaataa aaaagcacgg ggcagttctc
     1621 actactgccc aaagtggttg attagagtcg gcttctctaa ctccctatgt tgtgcttatt
     1681 aggcttatcg caagggaaca gtttttagct ctgccaagcc acatagtgtg cttactacta
     1741 tgtgtccatg tcaccatgaa ttgccgaacg gtttaacgag aaagtatagt agattgaaac
     1801 aagatgtgaa caaatcgatt aggaaagtca aattaatttc tagaaatatt ttaacagtca
     1861 taacggacta ttccagattc aatctactat attactttta ggtttatccc aactcaatta
     1921 tgacatcttt ttttcaaaag tcaatatatc tcactctttt caacgacaag aaagaggctg
     1981 ataatcgacc aacctctgtt tttagataca gttcaagtcc aaactattct ttatagaaaa
     2041 gtccgataaa ttcgagcaat agttaacata cttacaaata taactcccaa aatagataac
     2101 actattttca caaaactcag ttccgaacct atgacatata tatgaaaaag aggggctagt
     2161 cctacacata tatacaataa gtagccaaca agttttatct caccaattcc tgcaaaaaaa
     2221 tgtttcatgt aacgattctc catttactct attaaatcaa ttttatttta gactatcata
     2281 acacaatcac ctcttcaata aaaaccattg gcgaaatact attctgaagc attgatagct
     2341 cagatttctc agaatagagc tgtcctaact atcgagcagc tcaaatacat atatatgagc
     2401 aattctaagt ttagaattgc tataaaataa atgtttccag gctattctaa gtctttgact
     2461 gcttaaaatt ttacgttctg aaggattcta aagctagaac agctcaaaat cacgagaact
     2521 aaggtattcg aaacttcaga gtaatacaat ccccatagga attctccatt cttattaagc
     2581 atgattaaaa tgtaatccta acaagtgatc ctcgactgtg tttgtagcac ttagttacct
     2641 agataagact atttcccttt atcatatctg attttaagcc gttctaagat ttaacctatg
     2701 tttctattac ttgctatttt taaataattc gaattccttt tctttgataa atggaactga
     2761 aaaattagaa aaaagaagta aaaccgaaaa caaatagcct gctttttgaa tcactaaaag
     2821 atatcctaaa aataagtaaa ctataacatc caatgcgaaa agaaaaaata ttctcctctt
     2881 cattaaagta cttgtgtcaa ataatctgat gaataaaaat tttatcgtag tatctacaca
     2941 aatttttatc aaaaagataa gagccaatac acgattatca actgtaccgt aaagaataga
     3001 tggaaatata gttaatataa aactagaaat ctctaaatat tttatccaag gagattgaga
     3061 caccttgctt ctaaactgac taattttctt atattcgtta gtcaatttag tagcaaaatc
     3121 ttccccaatt aaatgaaaga ttgctaactc taggataaaa acacttatta atacggtata
     3181 agtcaaaaaa ctttctggga aaaacttatt gattaaaatg gggaaactca ttaacagaat
     3241 cgaatttatg gctagacaga tagatactat tttatttttc acagaatata gaggtagtga
     3301 tactattgag tagataaaag ctaaaaaaat aagcaaaaaa tactccgtgt catttataat
     3361 cgccctgaat gataaaaata tatacatcca acatacgata atatgtattt ttcgaatctt
     3421 atctacatta ttcatcttac tgtcgcagat ataaatccat cccaaggata agggttcccg
     3481 ctaatatcac aacctctatt aagagcacca tatccaatac agtaagctat ttttcctgct
     3541 gctgcaccaa taagccagcc tccaagacct ccaaccttaa tatagtttat tagttttttg
     3601 gttaaaactg cagctccagc taatgctata aaagttcctg aactcatagc taaagctacg
     3661 caaattcctt gacaagcacg cttgcttaaa taagctcccc catcaagata catcatttct
     3721 tcttcatcaa tcacaacata attatttggt aatacaagtt ccatttgttt tctcctcctt
     3781 agttgaaatt gtttcatttg ttttacaaat aggacgaact taaactatct ttttattact
     3841 cagtaataat ttccgagatt tcattttatg atactctcta ttcatacaga aatcaaaatt
     3901 ttgccttaac caacttgtat aatagaaaaa atctaattga tttattctga tgagctgtat
     3961 tctaatttta tcaacctttt cttgccagtt gttattgtta ctaatagaaa tctcatacag
     4021 cagtaactcg acaagacctg tacacagaag ggtgttatga gaatcttcaa ttttactcag
     4081 aatatcctca aaaagttcac tatccgttaa aaaggtggat tgattcatcg catcatacag
     4141 ctgaagagac attaagtcag aataactgag atctgatttt tgtattttat cctttaacgt
     4201 atttgtcaaa tcactttcaa acgaatcttc tttttcccat ttattttgat tgaaaagaaa
     4261 ttccgtctta ttaaaaacga gatgattgat atccattata gtccaaaaaa atattgtagt
     4321 aagcataatg atgacaaaag gaatttttaa aataaatact aggataatag caatttcaag
     4381 aataaaactc catataatcc tagatcttaa atcatcaggc gacaaacttt tacgatggaa
     4441 tgaaaaatag ggcgagaacc tcacatttac tttcttcctg cctataaaaa taaaaggaaa
     4501 aatcgtaata agagcttctt tcttgtacaa atctttcaat gcgtatagta tgtctaaaac
     4561 tatttttgat aaaatcaaac tacagaaagc aagactcata ctaatcacaa aatcaagggg
     4621 agattctaga ttcaatagta agttattcac taggacatgc aactctagcc acaagacaaa
     4681 aagagggagc attagtaaga aaacaattag tttacgcatt ataacaatta gtaaaattta
     4741 cgcgtccata aagcatacgt aattcctgca actgaaatac ctccaattac agccaatgcc
     4801 gcattaacag ctgctactga ccctagtatt ggagcgaaag cagaaacaac ataagtataa
     4861 gaatacactc ttgtagacca tattgcagcc cataaaccag tttctcttgc ggcaaaccta
     4921 aatcctgagg aagctctcgc taaacctttt atattatttt taaatgtgtt ccagtctccc
     4981 ccatcaaggt acatcatctc ttcttcatca atcacaacat aattatttgg taatacaagt
     5041 tccatttgtt ttctcctttt tattaagcat ggttaggatg gtttcctaac aagtaatcgt
     5101 cgtctgtgtt tctatcactt agctacctag ataagatatc ctttctctac cttatttgtt
     5161 tttataggtt acctaaggtt taaaaccaat tattgcttga aacttaacat ttctaaaatc
     5221 caatcaagat aggtttcttt atcatagaca atccgcactt caactggcat atccttttgg
     5281 aggacgactg tctcacttcc atgttttaga gttaaggttt ctaattctat catgacttta
     5341 taaagactaa tattgccttc tttcgtttct tgggaaattg ttcctgaatc aatctgtctg
     5401 acttgtccct ttagtgttcc atatttttga ctatttacac cagtaatagc aacatcagct
     5461 tttgctcctt tcgaaacacg agaaatatca ctcgcaagta caaaagcttc tacatagtaa
     5521 cctttttctt tccctgaaac ttctgctatc gtttgcccct gctgaataga cattccttgt
     5581 ttcaaaggta acagataatg cagagtacct tcatttggcg ctaatatact atgagcttta
     5641 tcttgacctg ttgccactcc aagattagcc tcaagctctg taatactttt attgttgttt
     5701 gaacgagcag tacctaactc actaactaat tgagcataaa tattataagc ctgagaagtt
     5761 ggatcattat aggtacggtt catatcctta atattgcttt gttgactatc aatctcgcta
     5821 ttcttagaag taatatttgt ttttaatgct tcgatttttg ttgttatttc tgatatctta
     5881 gtttctaact tagctttgtt atcagctgat gtcgtatctg atagagaagg tgagtctcct
     5941 tgctgttgaa gttgaagcaa ttcattttgt agagcttgca agtcggcatc taactgattt
     6001 ctttcagctg ttattttatt caacttcgta tattcatcct gaatctttga atactgggta
     6061 ccattattat aattttccga atttaactga gataggtagt attcaacttt cccataatat
     6121 tcctgttctt caccagaatt agataaatga ttgtatttct catttaatga ttgttcaaat
     6181 ttttgaaaga tagcttcttt tgcacgtaac ttctccaatt gtttatttaa agagctcgct
     6241 tgtaaacctt cttgcccact tgataacgaa ataatgacat ctccagcatt taccatatct
     6301 ccttctgact tatgtaaagt aactaccttc cctgaaccaa ttgctgatag gaactctgta
     6361 cctgttataa ctgaatttcc attcgctttt acaatatagt ttttgggtat ataagctgcg
     6421 ccaaccaatg caccgcttaa gataatagca gttgaaataa tgagaataaa cgcaaaagct
     6481 ggtggtctct tatcaaagaa aatacgagaa taacgtaatt ctgatttatt atataatttc
     6541 ataggcttac aattggtcta aaaatatcta ctaccatttt ttcaggagaa gaattaacat
     6601 aaactgtata gacaatccca tccgtttgaa tatcattttc atagacatat agatccaatt
     6661 tagaatacgc atactgtaga tactctggac tgtcttcaaa acgaacatat aaacaatatg
     6721 gaacagagat agaatcctgt acatcataaa tgttactgta ctgttgagca ttatgagctt
     6781 gaatataaaa ctcaaaatca gtcgttatta atccatcatc atgaatagta gtaccacaac
     6841 tttttacaat taatggacca aaaatttgtg cttttaacaa ctgcaaatgt tgatgaaatt
     6901 tattaatttc ctgatctaca tcttctactt ttgtatcatg taacttttta cagataactg
     6961 actttagtac cagtttttta ttatctttta cctctaactt agccataagt aacctcctct
     7021 gtatctaaca cagcctgtga ctgaatttgt tgattcactt gaacgctctg caaaccaacc
     7081 attctagcat actttccatt tttcgccatt agttcttcat gagtaccata ttccataata
     7141 gtcccatttt ctaaaaagca tatcttatca catcgaagaa ttgtagacag cctgtgggct
     7201 actacaattg ttgtcttatc cattatttta ttaaagatta aatcctgaat aatctgttca
     7261 ctaaatgaat ctaagttaga ggttgcctca tcaaatatat acaaatcagc tttactcagt
     7321 agtgctcttg caatagccaa tcgttgtttc tctccacccg agaaattttg accgccttct
     7381 tctacaaagg agccataacg attttgaaga cgttgaatcg tatcatgaat accaacaata
     7441 cgacaaactc tcaccatatc ctcatatgta acagaaggat taccaatttt tagattatca
     7501 ataattgtcc ctgtaaagag ttctatggtc tgaggaatgt aggaaatttt cttacgtagt
     7561 ttaccatagt caagatctga taagtcattt tctcctatac gaattttccc ctcactcgga
     7621 tttataaatc ttaataacaa acgaactagc gtactttttc ctgctccgct ttctccaaca
     7681 aaagctattt tttctccttg tttaattcgc aaattaaagt ccttgataac aggagggcgt
     7741 gaaccatagg caaatgttac atctttaaat tcaatgtcat cacataaggt gaagtctcta
     7801 atactataat ccaaggcaat gtcttcacga tctacttcca tcaattcttg aagccgacta
     7861 accgcaacct gtacctcttg aaaggttaac tgcaagccaa ctaaattctg aataggttct
     7921 gtaaaatatt gacttaatgt ctgaaaaacc aagaggtccc caatagtcat ttttccatca
     7981 atgataaata aggcgcccac tcccataaat aataacccac ccatggttga ggtcattgaa
     8041 gatattgtag attgaatatt ctgcaaaaca ccctctttat aaccaatttc taaagtatga
     8101 acaaattttt cttcaatttt gtttaaacgt tgttcctcat catgctgaga cttaatggta
     8161 tcaatgttac gaatagattc aattaactgt gaattaagaa gtccatttgc ttccatttgt
     8221 tcatgattaa tttttttata aggcttttta aaacagtata taagaatgat gttaacaata
     8281 accataaaaa ctaatatcag aaataaagat tgattaatag tccaaaggac aaccgcacta
     8341 ataactgaca aggtgatatc catgactaat gaaatagaga ctgacgtaaa cacattcttt
     8401 atcgtcatcg catcttgaaa tcttgttaaa acatcaccaa ctctacgact tccaaaaaaa
     8461 ctataaggaa gatgaataat atggtcataa tatcccatta aaaccggtat atcaattttt
     8521 cgagatagaa acaaaagaac gtgctgacga aatgcagata gaagagtctg taagaacgac
     8581 actattccaa atactatcaa aaacatatac agactatttt ttaaagcata tggaatcacc
     8641 tcgtccatga taacttttga aaagagactc gataaaatac caatgatact taaaacaaag
     8701 gaagctaata tgactgtact aatcaatcct ttttgattaa aaattaacct tccaaataaa
     8761 tcaagaagtc cttttccctt tagtttccct ctttcaaaat ccgaatttgg aaccataaaa
     8821 agagtaatac cttgataaat ttctcccagt tcgtcacttg acatcttgcg tatgccacta
     8881 gcagggtctg ctacgtagaa cttactattc cttttgatac tatgtagtac cacaaaatga
     8941 ttttgaccta aatcattctt aacttgaaga atcgcaggaa atgttaattt tggagtcaaa
     9001 tcttccagtg ctactcgaac agcttttact gtaaaattca acttattcag acctgaaaca
     9061 ataccactga cagtcgttcc atacatgtct gtaccaataa tttccctaat cttcatgatt
     9121 gatagttcct ttttgtaaga taaaagaact gttgaaacaa ctgccgcagc acaatctgac
     9181 tggtcatgtt gcatcgtaca aggatatttt tttaacatag aaatactcaa ttctttagaa
     9241 ttaatctaac ttttctttga tgtcacccaa acctcaatca ctgcccagta gttcttgaat
     9301 taatttattt tcaaccgtat cattctttgt tcttgatatc tttccaagca ttgtagtaca
     9361 gcagattttt gcccaaggac tgagcctcct ttaacaactc aaactccctt acattatatc
     9421 ggccagcccc atggaaagat tatagccaga ctaatcaatg atataataca tactagaata
     9481 caaaatattt ttttattcat actttttctc ctatctttat tttctaccta catagtacct
     9541 cttattaagc tcattttaaa attacgttaa cttttttcac aaatttattt cgactttctt
     9601 ttttactttt tacattgcta tgatacaata tttttaacaa aattttattg tttgttaact
     9661 tttttcacga aaaggagaaa atcatgcgtt atgatttcgg aaaggtctat aaagaaatac
     9721 gtgagtcaaa ggggctgacc caagaagagg tctgtggggg tgttctctca agaaccagct
     9781 tatcaaaaat cgaaagtggc aagacaaccc caaaatatga aaatatggaa tttcttctcc
     9841 gtcaaatcaa tatgagtttt gaagagtttg aatatatctg tcaactttat caaccaagtc
     9901 aacgcacaga gattatgcaa acctatctca atatgcgttc cattatcggg accagcgatc
     9961 ttgtcaattt atttcaaaaa tgccaagact acctcaagac ccaccacgat ctccctatag
    10021 aagaaatcag agatatgctt gaagttgtta tttatctccg tcaacacggg gcaggggaac
    10081 tatcaaaaca cgcagaacag gttgtcaaaa aactttggaa aaaaattgaa aaacaagata
    10141 catggtatga gagtgatcta aaaatcctca ataccattct tttcagtttt cccattgaat
    10201 acctccatct catcactgga aaaatattgc aacgcctaga agtctataaa aactatcaac
    10261 atttatatga cttgcgaatg acaattctat taaacctttc cacactctat ctatacaatc
    10321 aagataaaaa catgtgtaag caaatctgct acactttact ggaggacgcc aagaataaga
    10381 aaagctacga taggctggct atctgctatg tccgtattgg gatttgtagg gatgatgcga
    10441 aacttatcca aaaagggttc tcccttctgg agctaaccga ggaaacttct atactgtctc
    10501 atctcaaaaa agaagtagag atctattacc aagcgaagga aagataaaaa agccgaggga
    10561 tttcctcgac tctttacata ttatttgttc gttagttctt aataccagcc attgttaaac
    10621 cagaagtttt tagctctgcc aagccacata gtgtgtttac tactatgtgt ccatgtcacc
    10681 atgaatcgcc gaacgattta acgagaaagt atgactttta cgtttatccc aactcaatta
    10741 tgacattttt ttcaaaagtc aatatatctc actttttcaa cgacaagaaa gaggctgcca
    10801 atcgaccaac ctcttattct gaacccatca ctccatcact ttttagcttc attcgctttc
    10861 ttagcgactg caatctggta ttcgacttgg tcaaaccctg tgcctcccaa ggaatttcgt
    10921 ctttgaacag cagttttagg ttgcaagtag acatagatat cctcggtaat gagagaatga
    10981 taggtttgta attcctccaa agtccaatct tgaagatttt tagcagactt gatagagtct
    11041 agcactaatc ttcccacaac ctcatgagct tctctaaatg gcaagccttt ccctgccaaa
    11101 taatctgcca actcagttgc atttgaaaag tccttctctg ttgattcttg cattttttcc
    11161 ttgtttacct gcaaactaga taacatacct gccaacacat cgagggaatt taaaatcgtt
    11221 tcgaccgtat caaacattcc ttccttatct tcttgcaaat ccttattata agctaaaggc
    11281 aaggacttca tgactgtcaa cagtccaaac aaatgcccat aaactctgcc agtctttcct
    11341 cgaatcaact cagccatatc tggatttttc ttttggggca taatagagga acctgttgta
    11401 aacgtatctg acaaggtaat gaattggtac tcaaaactac accaattgat catttcttcg
    11461 caaaaacgac tcatatgcat catgagtatg ctggcatttg atagaaattc taagataaaa
    11521 tcgcggtcac taacagcatc caaagaattt gtataaggtt gcttaaactc cagcaaatcg
    11581 ctagacaatt ggcgatcaat ggggaaagtc gttcctgcca aagctgccgc acctaaaggg
    11641 cataggtctg tatgcttctg gttaaattca aaacgttcac tgtctctttg aaacatattg
    11701 tagtaagcca tcaggtggta ggcaaaacta ataggctggg catgttgcag atgggtatag
    11761 cccggcatga tcgtcgccac atgattttcc gccaagtcta ataaaacacc cttaagatga
    11821 gccagtttat ctaggacata gcctagttgt tccttgagat acaagtgcat atctgtcgca
    11881 acttggtcat ttcgagaacg agccgtatgt aacttccctg caaggggacc aattttttct
    11941 gtcagcaaca cttccatatt catatgaata tcttcgtttg cgatatcaaa gtcaagttga
    12001 cctgcctcta gctcttctaa aagctctttc aagcctactt gaatcttttc tgactcctcc
    12061 aaactcaaaa tgcccgtctg acccaacatc tgaacgtggg ctaaagaacc aatcacatca
    12121 aatttagcta atttctggtc aaaagatata ctcgcaccaa agcgctctac ccagtcttcg
    12181 acagtacctt caaagcgacc accccataat tttgtattct tagccatatc acatccacct
    12241 ctctatccaa tcgtcctatt tggcgctttt ttgaacctca gaatgaacct tggttggaag
    12301 tccccataac tcaataaagc caacagccgc atcttggtca aaggtatctg cactagtata
    12361 cgtcgccaaa ttttcatcgt aaagagaatt tggtgatttc cgagccacga cctgagcgct
    12421 cccccttata cagtttgact tttgcagtcc cattgacaac tttttgagtc tctttaatat
    12481 aagcaatcaa ggcttgtgta gccgaactaa accacaaagc attataaatg agatttgata
    12541 attcattttc tatgattggt ttaaaatgag ccacttctct cacaagcgtc aagtcctcaa
    12601 tttccttatg agctgtcagc agggtcactg cacctggaca ctcatagatt tctcttgatt
    12661 taatcccaac caagcgattt tccacgtggt caatccgtcc aaccccatgt tttccagcta
    12721 tttcattgag tttttgaatc aaatctgcca attttaacac ttctccattg agggaaactg
    12781 gaacaccttc actaaactca atctcaatgt attctggcat atctggagct tgctctggag
    12841 aagttgtgat gccaaaggct tcttctggag cctgattcca tggattttcc aaaataccac
    12901 actcattggc acgtccccaa agattttggt cgacagagta gggattgtca aggtcagcag
    12961 gaacaggcac cccatttttc ttggcataat aaatttcttc ctcccgagac catttccatt
    13021 cacgaactgg agcaatcact tttaaattgg gatccaaggc tgcaatcgat acttcaaaac
    13081 gtacttggtc attcccctta ccggtacaac catgagcaat tgtagtcgct cctatctgat
    13141 gcgctatttc aaccaatttt ttagaaatca gagggcggct caaggcagat accaagggat
    13201 acttttgttc ataataggca tgtgactgat gagccactag cacataatct gtagcaaatt
    13261 cgtccttaac atcaatgaca taagattcta ctgccccaac cttaagagcc ttatcatgga
    13321 tgaaatctaa gtctttccct tcacccacat ccatacaaac tgaaacaaca tcatagtctt
    13381 tctttaacca ggtaatagca actgatgtgt ccaaaccgcc agaataggcc aaaattactt
    13441 tttctttact catgttcttt tccttctttc tatttttcaa tggatgcttt aaaggcatcc
    13501 tcaatgagtt tgtctaattc cccagactcc ttcaactttt gaatagtttt atcgactgcc
    13561 tctttcaatt ccttactatc ttttttcatg gctaccgagt aggaatcatc ttgctctttt
    13621 tcaaaattga ggtctgcgat tgctaaatca ggattatttt ccacaaagcc cttggcaact
    13681 ggttcttcaa agataacggc atccacttgt cctgatttta aatctgtgat taaattccca
    13741 tttttaggca gagatacgag ggaagaattt tgtagcaaat ctttcgccat cgtctcttga
    13801 atcgaacctt tctgggctcc gaccttcttc tgcgctaagt cgttgacaga ctgataagtg
    13861 actaaatcag attttttgac aatgagttta ttttttgcag tatagtaggg aatggaaaag
    13921 tcaaacacct tgctccgttc atctgtctta gaaacacctg atatggcaag atcagctttt
    13981 cctgattgaa cactagccag tacattgtca aaactcatgg gagatagttc caattcgaca
    14041 cctagttctg ttgcgatagc cttggctaat tcgatatctg aacccacaat ctgatttttc
    14101 ccatcaacca ctttttggta ttcaaatgga gcaaaatctg gattgagggc tacaaccaat
    14161 tttcctttgg acttgatggc ttcaattcca gccgattgat tgttactaca agcaaatagt
    14221 agggggagca tcactaaacc aaacatcgtc atcaacacct tcttcatctt attcataaca
    14281 aagcctcctt tatgtttatt ccttttgttt gtataaataa tacacctatc ttcatccttt
    14341 gtcaagccta aattgtaatt tttttcaatt taaaacagaa aaacctagga aaattacata
    14401 aaaatgtcat tcctaggcgt atttatgcta ttcctctctg gaaaatatga gtattcagtc
    14461 agtcaaaaga agctgaacga actcattttc cctcgcccaa ttcaataatc cgatgacatt
    14521 gttgggctac ataagcatcg tgggtcacaa taatgactgt tttcccttct cgattcatct
    14581 ctaagagaaa cttcaagacc aaatctctat tttcaggatc cagcgaacct gtaggttcat
    14641 cggctaaaat cagctggctg ggttttaaga tggctctagc aactgcaatt cgttgttgtt
    14701 cgccaccaga caactcggag accttttgat gcaaagtagc tgacaaacct actctctcta
    14761 aaatctcttc cacctttttg agcttatctt tcttagacaa ttttacatat ttcagcgcca
    14821 gcataagatt gtactcgacc gtttcatcat caatcagggc aaaattttga aacagataag
    14881 agatatgttc acggattatt gtttgcgact tagcagaatt gaccgctaga tttgtctgac
    14941 caaaaatctc ataccgtccg ctataatcac catctatcaa acccaataaa tttaacaagg
    15001 tcgacttccc actaccactc ttaccaacaa tggcaaccaa atccccctga tcaatcctga
    15061 gagacaagcg atccaaaatc actttccccc caatggtttt ggtaatattt tccaactcaa
    15121 tcataagatg ccccctttca ataactctac tagacttctt ttctccatcc tagaagccaa
    15181 ggctagcaca aatagtatat ccaaacatgt aaagcctgca aacagcagga gtggcaagaa
    15241 cgcatgggca aagaaaatca agactagaag agggagacta tagcccagca agagcagaac
    15301 gaggagagga cggtagcgat cgaccagttt ccaccccata aacttcttgg taataatatc
    15361 cctgcgcttc aataagaaag ttattactag taagaagtag gaaatcatca tgctaaagag
    15421 accaaacaaa gcaaaaagta ggttaaaatt ccgaacagca tctcgataag aatccacttt
    15481 ctcttgttga atggcttgaa tagatgaaaa ttttaaataa tttccatctg acaatttctc
    15541 aactaactct gtaatctctt tttgatgttg aaccgtattt tcaattttaa tcggattatt
    15601 taagccagtt gttgacaggg aggctttctc atcccacatc atatcagaat cattgaccaa
    15661 gctaataatt ggattggaga gattttcctt tcgcttatca ctatatggga aaaatgacca
    15721 atctccttca taataggcaa tctcgacatc catctcctct atcgttcgtt tttgctgctc
    15781 ttcatacttc atcgaatgaa aggcaattaa cttccccaag agctgatttt tatcttcttc
    15841 acctttcgta cttgctggca tcaaaataac ttttttaata ccagtatctg gtagcttgaa
    15901 tcccttgctc tttagaaaat tgcgattggc atagtaaaca tccaccgtat ctgttaactg
    15961 atattgctga atctgttctg attggacaaa attttttaca ggaagactgc tactctgcac
    16021 atagcccgcc tgcgtttttt ctactaaatc ctgataaaat cgatagaaat aatccaatgc
    16081 cttccctgag cctgccaact gctcttgcca caagttgtca ttgagttgga aagtttctaa
    16141 ggtcagataa tttccttggc tgatccactg tttctggtaa tccaactctt tgttttcttg
    16201 ctccaaactt tttcctaccc caactagcaa gactgtcagt aaaatggtag ttccaatttt
    16261 catcaaataa ttaaagagta gaccaaattt gaaagatgaa aaacctttca gcagagagct
    16321 gattgtcatt ttttggatta agaggtaagt caaccaactg ataaagagat aaagctgcaa
    16381 cagcaaaaaa tgagacaacc acagcatagg aaacaaatct tttggcttat aatcaagcaa
    16441 gaaaaacacg cctagattga tcacaagagc cccacctagg aggaggtaaa ggttgccttt
    16501 tacaacatca gctaaaacag ccctatcttg aaaaccaagt aatttttgta ccccaactcg
    16561 tttcatctcc atcatcggtt gatacactgt cactaacaca agaagcaaaa tagccaagac
    16621 aaaaacaatg gcagataaaa gcaaatctcg atttatgact tccactgcac ttttgtaggt
    16681 cggctctagc aaggtagcct ggtctatctt gaaaaaatcg ctccatttct gtacaatcct
    16741 atccttgtcc atctcttgtg tagaagttat cgtatagcga ccatttaaac tacgagatgt
    16801 atccttgata taggtttgaa aagtcataag ctgaataggt ttggctttta gaaaggtcgg
    16861 aatcgtacca agtttattgg aaatttcttt attactatag actccttcac catctgtggt
    16921 aaaatcaaga gaagaaatcc caaactcttg gtaggggaag gtatctttat caaaaacacc
    16981 agacttgacc acctcatcgc cattatctac tttgataata gagaccttgt cttggcttgc
    17041 aacctcttca aaaaactgga gaatcgtttc tgtcggttta gtgacatctt tcaagtacaa
    17101 gtcaaatgaa taagttgtct tgcccatctc ctgaatccgc actatttctc gtgtaacatt
    17161 tacattcagg acaaaaaacg tagtacacag caagagcagg agcatacaaa gatgactgat
    17221 ttttttcata gagatacctc ccgtgaagaa actccctctc caaaagggga gggagaattt
    17281 taattaaaat ccatagaaat attccattcc cgttggtggg aatttgaaga ttgaagcccg
    17341 agcccacgcc tcagcttctg cacgatcctt agagaattta tttccatctt taacagttgc
    17401 tgtatgagag cgagtagaat gtaaataatc agaataacca aaatttcctg accatcctac
    17461 tccatagttc cattgaccac catcaaccca tactgccaaa acacttgtag aagcaagtat
    17521 actacatacc attaaagatg caacactaat tttctcatga tttatttctc ctattatcga
    17581 gagctattcc gtagaaacag ctatagtaat ttatcaacaa gtatcgtagt ccattggact
    17641 caccttcctt ctatctcatt tcatttttaa acaacgaact tactcttaac taggagaata
    17701 gttctcttct gtatcaggtc tttgaacaac cagagtagta ttaatcacac tctaactatt
    17761 actcaagaat cagcccaata aacaatatgg atagcgcttt caaattttta aactctatcc
    17821 catcctttta tctatattat gagcgaaaat ataataactg tcaagtaatc gaagtgaatt
    17881 ttataaaaaa aattacaagc caaatttgca aagtttacaa taagccgcta gggcaatcgt
    17941 ctatcagaat gtccgtttat ttgtcaataa tccgagaaaa tcttgcaacg cttagaagtc
    18001 tataaaaact atcaacattt atatgacttg cgaatagcaa tcctgctcaa cctttccaca
    18061 ctctatctat acaatcaaga taaaaacatg tgtaagcaaa tctgctatac tttactggag
    18121 gacgccaaga ataagaaaag ctacgatagg ctggctatct gctatgtccg tattgggatt
    18181 tgtacagacg attctaaact tatccaaaaa gggttctccc ttctggagct aaccgaggaa
    18241 acttctatgc tgtctcatct caaaaaagaa gtagagatct attaccaagc gaaggaaaga
    18301 taaaaaagcc gagggatttc ctcgactctt tacatattat ttgttcgtta gttcttaata
    18361 ccagccgttg ttaagccaga agtttttagc agctgtccat gaaccgtaac gtcctgcaac
    18421 gtaggcatct gctacacgtt cttggttttc agctgagtag tcaccgttca ggtatgaatc
    18481 tgttaattgg taacgtccga tataacgtcc atttgtagct gtatagctac cacctgattc
    18541 tttttgagca atccattctt tggcttctgc ttcagatccg cttacagttg aaacaactgt
    18601 ttcacttact actggagttt ctgctactgg agctgaaaca gtttcatctt gagcggctgg
    18661 tgccgcataa gtagctggcg ctggtgttgc aacaggcgct acagggccat cgataaccaa
    18721 ctcttgacca acataaatca aatgaatgtt atcaatgtgg ttgttttctg ccaatttttc
    18781 aactgttgtg ttgtgagttt cagcgatttc tgaaagtgta tcaccttctt taacagtgta
    18841 agttgatgat tcttgagcag atacaaatga tggagcaaat actgcaaaca aggcagctac
    18901 tcctgcaaga gttgctttaa tctttttagt tattgatttc atattcgaaa attctccttc
    18961 tttctatagt tctatcatac cctttaaata ttaccgtttc ttgacacttt tatgtagaaa
    19021 tattacaaaa ttatttttta tttccctaaa taaggtgttt tttgtcataa aagatactat
    19081 ttttatgcta tttgaggtat tagaaaggtt ttcatccaca attaaagcca agcccctcat
    19141 tctttgatat aatagagata agaattttta taaggggaaa ctgatgaaat cacttcgttt
    19201 tcaatctgtc tttgatatca tcggaccagt tatgattggc ccatctagta gccatactgc
    19261 tggtgctgtt cgtattggga agattgtctc ttccattttt gatgatactc cgacagaagt
    19321 tgaattccaa ctttttaact catttgccaa gacctatcgt ggtcacggaa cagacctagc
    19381 ccttgttgca ggtattttgg gaatggatac agatgatcct gaaattccaa atagtctgga
    19441 aattgcccac aagcgtggta tcaagattgt ctggaccatt cagaaagaca gcaatgcccc
    19501 tcaccctaac accactaaaa ttactgttaa aaatgcccac aagaccatca gcgtgactgg
    19561 tatttctatc ggtggaggaa atattcaggt aaccgaactc aatggttttg ccgtctctct
    19621 caatatgaat acaccgacta tcatcatcgt tcatcaagat attccaggta tgattgccct
    19681 tgttacagag gcgctttccc gctatggtat caatatcgcc cagatgaatg tcactcgtga
    19741 aaaagctggt gaaaaagcca ttatgattat cgaagttgac agtcgcaact gtgatgaggc
    19801 tatcgaagaa attcgaaaaa tccctcatct ccacaatgtc aatttcttta aataggagga
    19861 agcatgtttt attctatcaa agaattggtc gagcaagcag atctggactt tcaaggaaat
    19921 gtcgcagaac tcatgattac aacagagttt gaattgaccg gtcgcgaacg tgaagaagtc
    19981 ttccttctca tggaacgcaa tctggaagtt atgaaagcct ctgtccaact tggcctcaat
    20041 gaaaataaat ctcgtagtgg cctgacaggt ggagatgctg ccaaattgga tcactacatc
    20101 gaaaacggaa aaactttatc agattacacg attctctctg ctgcccgaaa tgctatcgca
    20161 gtcaatgaac acaatgctaa aatgggcttg gtctgcgcta ctcctaccgc aggaagtgcc
    20221 ggttgtctcc cttccgttct cactgctgct attgaaaaat tagacctcag ccacgagcaa
    20281 caattggatt tcctctttgc tgctggtgcc tttggactag tcatcgcaaa caatgcctcc
    20341 atctcaggtg ctgagggtgg gtgtcaagct gaagttggtt cagcctctgc tatgagtgct
    20401 gccgccttga ctctggctgc aggtggaaca ccttatcagg ccagtcaagc tattgccttt
    20461 gtcattaaaa atatgctagg cctcatctgt gaccctgttg caggtttggt cgaagttccc
    20521 tgtgtcaaac gtaatgccat gggagctagc tttgctttca tcgcagcaga catggccttg
    20581 gcaggtatag aatctaaaat ccctgtggat gaagtgatcg atgccatgta ccaagtagga
    20641 gcaagcatgc caactgcctt tcgtgaaaca gctgaaggtg gactcgctac cacccctact
    20701 ggtcgtcgcc tccaaaaaga aattttcgga gaataagctt atcaaatagg agaaaccatg
    20761 acctctatca cagcgatttt tttcgatttg gatggaaccc tcgttgatag ttctatcggg
    20821 attcacaatg cctttaccta tacctttaaa gagctggggg tgcctagccc tgatgccaaa
    20881 actattcgtg gttttatggg accacctctc gaaagtagtt ttgcgacctg cctgtccaaa
    20941 gaccaaattt ctgaagccat gcagatatat cgttcttact ataaggcaaa aggcatctat
    21001 gaagctcaac tctttcctca gattatagac ttgcttgagg agttatcgag cagttatcca
    21061 ctctacatca ccacgacaaa gaatacatct actgctcaag acatggccaa aaacttggaa
    21121 atccatcatt tctttgatgg catttatggt tctagccctg aagcacccca taaggcagat
    21181 gtcattcacc aagccttaca gacacatcaa ctagcaccag aacaagccat catcatcgga
    21241 gataccaagt ttgatatgct gggagctcga gaaacaggta ttcagaaatt ggccgtcact
    21301 tggggatttg gagagcaagc agatctacta aactatcaac ctgattatat cgctcacaaa
    21361 cccttagaag ttttggcgta ttttcaatag catagactgg gcgacaactc tatttcagaa
    21421 gaaaatgaag taatactcaa tgaaaatcaa agagcaaact aggaaactag ctgcgggctg
    21481 ctcaaaacac tgttttaagg ttgtagatgg aactgacgaa gtcagctcaa aacactgttt
    21541 tgaggttgtg gatagaactg acgaagtcag taacatatac atacggcaag gcgacgttga
    21601 cgtggtttga agagattttc gaagagtata agtctctaca taataaaacg catattacca
    21661 aggttgtgta acttgatact atgcgttttt cttttttatt caatgtgggt tgtttgatta
    21721 gcaaaggcga taatagcttg cttcaactca tctccactga gagtgcggaa ctctccaatc
    21781 ttttgattga tggattctaa aggcatgaca ttaaccttac caacgaaaat cttatccata
    21841 acttgattat caacgagttc ggttgatacc aagagttctt cgtagagttt ttcacctggg
    21901 cggattccaa cttcaacgat tggaatttca ctttcagtgt ggccacttag aagcaccatc
    21961 ttcttggcca agtcataaat cttgactggt ttgcccatat caaggataaa gacttcccca
    22021 tctttggcat aagcaccagc atggataacc agacggctag cttctggaat ggtcataaag
    22081 taacgggtca tgcggaagtc tgtcaccgtt acaggcccac cttcagcaat ctgacgttca
    22141 aagactggaa tgacactacc acggctacca agaacattcc caaaacgaac tgcacagtag
    22201 gttgattggc tacgttggtt aaagccagtg acaatcaact ccgccacgcg cttggttgct
    22261 cccataacat ttggtggatt gactgcctta tctgtcgaaa tcataaccat cttagacact
    22321 ttagcttcat caacagcctt agcaacattg taagttccac ggatattgtt tttgaaggct
    22381 tcttttggat tgcgctccat cataggaaca tgcttgtggg ctgccgcatg ataaacaata
    22441 gcaggtttgt actgctcaaa gacttgcaac aaacgatcat agtcttgaat gtccgcaatc
    22501 acaggtacat aatcaatccc ttggaactta cgaatcaatt catgataaac aaggtagatt
    22561 gagttttccc catgaccgag taagacaatg cgttcaggat tgaagcgact aacttgacga
    22621 cagatttcag aaccgattga acctccagct cctgtgacta agatggtctt acctgtcagt
    22681 tctgcaccca gacgcgattc gtcaagacgg atttcctgac gacccaaaag gtccgtaata
    22741 tcaatttttt ggaagccagt acctgcttgg tgaaggccct gaacaacagt ttcaacctta
    22801 ggcatcttgt aacatttgac acccagctta ttacacatct gcaagatacg ctcatattct
    22861 gacggatcca gcgacggaat cgcaacgatg acacgctcga tttgatggcg tttggctaat
    22921 tcaggcagat tgtcataaga gcccaaaaca ggaataccac caagtttttg accctttttc
    22981 ttagaatcct tatccaaaat accgaccagt tctaattcac tggttggatg ttggtaacta
    23041 tccataaaga gagccccacc atcaccggca ccaatcaaga aggtccgacg gtgttctcca
    23101 tcaccactac cttttttgcg tctggagtag attaactgcc aagtaatccg tggcaataaa
    23161 atcaagaagg tactcaacaa gataaagaga atgatgaaac ggatggagaa gagtggcaag
    23221 aaggcataac agatactata tgacaagaca ctgctagcag tcacaccaaa aaagattttc
    23281 atgaaatccg taatcttgct gtaacgacta atgctcgcgt tcaaccccca aaaaccaatc
    23341 atcaattgat agaacaagaa ggccaaactc gtatagataa tgtagtcaac aggtgctgga
    23401 ttaatcagcc cataaaataa aatataagat acaattatgg aaaccaccat actgaaaata
    23461 tcaaatattc cccagaaaac ctgcttttgt tgtttattta aaatttccac cagatcaatc
    23521 acataatctg ttagtttttt attcatagaa atctactcct ccttaaaaga gttttactat
    23581 attgttatta tagcatattt ttatttattt ggcttatttt atccaaataa attattgttc
    23641 tcttgtactc cttcttccat ttaaatcctc taattaaacc tacaatcgtc ccaaggccat
    23701 aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat tagaaatcca tttttatgtt
    23761 ttaataaagt cagcaaagtg agtaatgaca aaagtagaaa ataggcacct aatagtaaag
    23821 ttatgaatac gaatgtgatc ggtaacaatg ctagactaaa cacaagactc aaaacaaata
    23881 aacaaggaac atagtgaaat aatgataaac acttaaactg aacatgactt gtcaagccaa
    23941 tccacaaacc atttgaatac ttttgatgca gcattttctt gaatgttggt cgaatatact
    24001 gataagatag aatacttggg ctatagcgga ttttataacc atgttctcga attctataat
    24061 gaatatcatt atcttcagtt cggccaagtt gctcatttac taaaccaacc ttctggaaaa
    24121 cctctcgttt atacatccca tgaaaaatag aagaaacata tctatcctcg gaactatttc
    24181 gataattggc aatgctactg ccaaacatat tttcctcaac aagatgcaag gtctctgccc
    24241 attttccttt tccttcgaca atcgtcggtc taggcccccc acagacaaat tcaccttgtt
    24301 gaataatagc cacattgttc attacaaaac tctcagtaac ttttgaatga gcatcaattt
    24361 ttaaaataag gtcccctaca gaatgtttaa ctcccaggtt aaaaccacta gcttgatttt
    24421 tcttaggatt gttatacaat ctaattgagt taaactctgt atcttccttt ataaattgct
    24481 gaatgatagc tgtggtccca tctgtggaca tagcatttat aaatagaatt tcaacattct
    24541 ctttaggata ggtttgattt tttaagtctt caattagacc aggcagatat ttttcttcat
    24601 tgtatgcact gattacaatg gatacgagaa gactttcaac attttgagtc actactactc
    24661 tcctgaattt ttccttccac cattctatca taattttcaa gactttccca tttttatctt
    24721 gaaagccaga aaccttactt gacattatag tgaaaaagcc ttaaaataag ctgttattaa
    24781 aatcagctag aagaggtatt atatgaaaaa gcaatcactc ttttttgttc caggtattat
    24841 cctgattggt gtttccttgc gaactccttt tactgtttta cccattattt tgggaaatat
    24901 ttcgcaaggt ctggaggtag aagttagttc gcttggtgtc ttgaccagcc tgcctctcct
    24961 tatgtttacc ctcttttcac cattttctac ccgactggct cagaaaatcg gcttggagca
    25021 tctcttcacc tacagcctct tcttcttgac catcggctca ctcattcgac taatcaatct
    25081 gcccctgctc tatctaggaa ccttgatggt tggggcaagt gtcgcagtca tcaatgtcct
    25141 gcttcctagt cttatccaag ccaatcaacc aaagaaaatt ggttttctga ccaccttata
    25201 tgtaacgtct atggggattg caacggctct ggcttcctat ctagctgtgc ccattacaca
    25261 agccagttct tggaaaggac ttatcctcct cctcacgtta ctctgtctag caactttttt
    25321 ggtctggctc ccaaatcacc gctataatca tagactagct ccacaaacca aacaaaaaag
    25381 tcaaataaag gtcatgcgta ataaacaggt ttgggcaatt attatctttt caggttttca
    25441 atccttgatc ttttacaccg tcatgacctg gttacctacc atgtctatcc atgcaggtct
    25501 atccagtcac gaagctggct tgctgacttc tatcttatct ctgattagca ttcctttttc
    25561 aatgaccatc ccaagcctga caaccagttt atctactcgc aaccgtcagc tcatgctcac
    25621 tctggtttca ctagctggtg tggtcggcat ttccatgctc tttttcccaa tcaataattt
    25681 catttactgg cttaccatcc atctcctcat cggaaccgca accagcgccc tcttccctta
    25741 tctcatggtc aacttttcac tcaagacaag cgcccctgaa aagacagccc aattgtccgg
    25801 cctatctcaa acaggaggct atatcctagc agcctttggg ccaaccctct ttggttacag
    25861 ttttgacctg ttccactctt gggtaccagc tgtagctgcc ctcttgctca tctatatcct
    25921 gatgactgtg gccctcttta cagtggacag agcggataag atcctttaaa cttctagttt
    25981 tagctagaag ttttttatat ataaaaattt tacacatttc tcttgacagg gctttctttt
    26041 agatgtacaa tgtatgtgta gaaaaattat atataaaaat cttacacatt agaaaaggag
    26101 gtttcccatg tactttccaa catcctctgc cttgattgaa tttctcatct tggctgtact
    26161 ggagcagggt gattcttatg gttatgagat tagccaaacc attaagctga tcgctaatat
    26221 caaagaatcc acactctatc ccattctcaa aaaattggaa ggcaatagct ttctgacaac
    26281 ctattctaga gagttccaag gtcgcatgcg caaatactac tccttgacaa acggtggtat
    26341 agagcagctc ttgaccctaa aagatgaatg gacactctat acagacacca tcaatggcat
    26401 catagaaggg agtatccgcc atgacaagaa ctgaatacct gactcagcta gaactctatc
    26461 tcaagaaact acctgaagct gaccgtatcg aagccatgga ctatttcaga gagctctttg
    26521 acgatgctgg agtcgaagga gaagaagaac tcatcgctag tttgggaact cccaaagaag
    26581 cggcccacga agttctatcc aatcttctcg ataaaaaaat caatgaagca cccgctcaaa
    26641 aaaataaccg acaaatttta catatcgcct tgttagccct ccttgcagca cctatcggca
    26701 ttcctctggg aatcgccatc ctcgtgaccc tgttcgcaat ccttgtagcc gctttgactg
    26761 tcattctggc tttctttgca gtttccatac tgggtatcat cggcggattc ctatttttag
    26821 ttgaaagttt cactgtcctc gcccaagcca aatcagcctt tatcttgatt tttggttctg
    26881 gtttactggc tatcggtgct tcttcgctag ttttacttgg catttcctat gtaactcgct
    26941 tcttcggtct actcattgtt cgtctggtac aatttgttct taaaaaagga aagagaggta
    27001 accagcatgc gtaaatggac aaaaggattt ctcatctttg gtgtggtgac taccgttatc
    27061 ggctttatcc tgctttttgt aggtatccaa tctgacggga ttaagagcct actttccatg
    27121 tccaaagaac ctgtctatga tagccgtacg gaaaagctaa cctttggcaa ggaagtcgaa
    27181 aacctagaaa ttactctcca ccaacacacg ctcaccatca cagactcttt cgatgatcaa
    27241 atccacattt cttaccatcc atctctttct gctcaccatg atcttatcac caatcagaac
    27301 gatagaactc tgagtctcac tgataagaaa ctgtctgaaa ctccgtttct ctcttctgga
    27361 attggtggga ttcttcatat cgcaagtagc tactctagtc gttttgaaga agttattctc
    27421 cgactaccaa aagggagaac tctaaaaggg atcaacatct cagccaatcg cggacaaacc
    27481 accatcataa atgctagcct tgaaaatgcg accctcaata caaacagcta tatcctccga
    27541 attgaaggaa gtcgtatcaa aaacagtaaa ctcacaacac ccaatatcgt taatatcttt
    27601 gatacagttc ttacagatag tcagctagag tcaacagaga atcacttcca cgctgaaaat
    27661 atccaagtcc atggtaaggt tgaactgact gccaaagatt atctcagaat catcctagac
    27721 cagaaagaaa gccaacgaat taactgggac atctcaagca actatggttc tatcttccaa
    27781 ttcacaagag aaaagcctga atcaagaggt acggaattaa gcaaccctta caaaactgaa
    27841 aaaaccgatg tcaaggatca actcattgcg agatctgatg ataatattga tctaatatcc
    27901 acaccaagca gacgttgaca aaaacgctta catctgctac tatggaagca tatttatcta
    27961 actaaaaagg aggttctacc atgaaacaag aatggtttga aagtaataat tttgtaaaaa
    28021 caacaagcaa gaacaagcct gaagagcaag ctcaagaggt tgcagacaag gctgaagaaa
    28081 cgatagccga tttcgataca ccaattgaaa aaaatactca gttagaggag gaagtctctc
    28141 aagctgaagt cgaactggaa agccagcaag aagagaaaat tgaaactcct gaaggcggtg
    28201 aagcgagaac agaaatagaa gaaaagaagg catctaattc tactgaagaa gagccagacc
    28261 tttctaaaga aacagaaaaa gtcactatag ctgaagagag ccaagaagct cttcctcagc
    28321 aaaaagcaac cacgaaagag ccacttctta tcagtaaatc tttagaaagt ccttatatcc
    28381 ccgaccaagc tccaaaatct agggataaat ggaaagagca agtgcttgat ttttggtctt
    28441 ggctagtgga agcgatcaaa tctcctacaa gtaagttgga aacaagtatc acacacagtt
    28501 acacagcctt tctcttgctc attctgtttt ctgcatcttc ctttttcttt agtatctatc
    28561 acatcaaaca tgcttactat ggacatatag caagcattaa cagtcgcttc cctgagcagc
    28621 tagctccttt aactcttttt tctatcatct ctatcctagt agcgacaaca ctcttcttct
    28681 tttcattcct cttgggtagt ttcgttgtga gacgatttat ccaccaggaa aaggactgga
    28741 cgctagacaa ggttctccaa caatatagtc aactcttggc aattccaatc ttcctcactg
    28801 ctattgctag tttctttgct ttctttgata gcctacgatt tacagctctc ttgtgtgtga
    28861 ttagcattgg aatcattctg cttgccagtc tccatatcat tacaagacca agtcaagcaa
    28921 gtgaaaccga ctccttctat caattattct tgtctgtcct tgtgaacgga gttattatcc
    28981 tcctcttctt tgtagctgaa gtggcactga ttggagatta tcttcgtatc ttggcctttc
    29041 tttaaaattc aatcctgtca tccttggcag gattttttct atgtcaaaaa agcaagtcga
    29101 ttgacctgct tctgctttac ttttcttgtg ctaatgtttt aaaatcttgt actaggatgg
    29161 gttgtatttc tatttgattg gcgtctagtt ggtggtaaaa agatgggggt aatacctcta
    29221 agaattttgc atagtccaag cgagctatgg attcatagtc ttctggttta gagtcgtctc
    29281 ctgtgatttg aaccaagtca atctcccact ggacttcctt atccaccaat tgctcaatat
    29341 aggctgcagg aacaaacggt tctctcggta aaactgtctt gactccttga gctagatggt
    29401 aaacgccatg cacttttcct tctccatcct gatagaagga aactctcgca aagtaggcat
    29461 ctgtctcttg aaccgcacgc acacgcgctt caaactgagc caagccatct gcctctaaaa
    29521 agcttttcaa gttctcacga ctaaagaaaa taggattaaa aattccttgg caaatcgtaa
    29581 aacgagctac agggtctgct agataggctt gaatacttgc ttggaaataa gcttcaaaat
    29641 caaaaccatc tagcccttca atatcagtcc ctgtataagc aagcaaagca tctaaaaatg
    29701 acttgataat ctgccagtct gtctttgtta gtaggtcagg aagatcgaca cggtaagcct
    29761 tttgaccatc agcataactg accttaaaaa gaaattgtga ttgccccact atcgcacact
    29821 caatatactc gagacgatta agaggctgac ggagatagac tacatcatag ctatgtgact
    29881 ccaaaccgtc tagcaaggcc aagatcgact tggcattcaa aatctcttgt tctcctaaaa
    29941 tgctctgttt atttggaata aaaaatgttt tcgccataac tggactcctt tgaaatcgtt
    30001 tacatacagt ataccttatt tttctgaaag atacaaaaac aaactttaga tttttgagta
    30061 caaagcatag aaaaacagcc cctgaggact gtttgatctt atacagtagc tgcctgatcc
    30121 aagctttcac cgatagcggc taggcgctca atcacttcag cttgtgtcaa ttcatttttt
    30181 gaaacatagc ggttacgtgg gtgaacacgg cactcgtgtg agcatccacg aaggtacttg
    30241 tcttcatttt cttctgatgt caagatacga cggttacaga agggatttcc acagttgaca
    30301 taacgttcac atggtgttcc atcaaaccag tctttcccta cgatggttgg gttgacatgg
    30361 ttgacatcaa cggcgatacg ctcgtcaaat acgtacattt ttccatccca aagctcacct
    30421 tgaacttctg ggtctttacc gtaagttgcg attcctccgt gcaattggcc gacatctttg
    30481 tagccttcac ggaccatcca gcctgagaat ttctcacagc gaacgccacc tgtacagtaa
    30541 accacgacac gcttgtccat gaatttttcc ttgttatcac ggacccattg tggtaactca
    30601 cggaagttgc gaatatctgg gcgaatagct ccacggaaat gtcctaggtc gtactcataa
    30661 tcgttacgtg tgtcaaggac aacggtatct ttatcaagaa gcgcttcttt gaactctttt
    30721 ggagacaagt aagcacctgt tgtttcaagt gggttgatgt cattgtcaaa gtcgttgtct
    30781 tccaaaccaa ggtggacaat ttctttcttg tagcgaacaa acatcttctt gaaggcttgt
    30841 tcattttctt cgtcaatctt gaaccagagt tcttccattc ctggaaggct gtgaacgtag
    30901 tccatgtatt tttgagttgt ttcatagtca cctgaaactg ttccgttaat tccctcgtca
    30961 gcgactagga tacggccttt aaggccgatt gatttacaga aagccaagtg gtctgcagca
    31021 aattgctctg cattttcaat tggagtataa aggtagtaaa gtaagacacg aatatctttt
    31081 gccataagat ttgttctctt ttctattctt aaattttcta aattttttat ttatctacac
    31141 tagtatacct gcttgagaaa acgaatgcaa tttatttgac tggaaattgt agagggttct
    31201 cgaaatttcc tgaatggtta aaataaggac aagagaaaac atggatatct atatccttgt
    31261 gccaaaaaaa ccactgccct ccccagacca acctgaggaa agcagtgatt cttattttag
    31321 gagttaggaa tgaatacacg aaatcaattt agctgattat tttttgtttt tcaagaattc
    31381 atcgtattgt ttttgcattt cgttcaatac tttttcgtag gcaccttcag atttcaattt
    31441 ttccatcaat tctggaatcg ctttatctgg gtctacagta ccagtgttga tagctgtatc
    31501 aaattgttgc attgtgttag caatagctga gatttcagat ttcacattgt cagtattgaa
    31561 gataaatcca agcgctggag attctttagc ttctgccaat tctttcttag aattttcgat
    31621 ttgttggtct gtaacgtttt cgttgatgta aaggatccag ttgttaccag tgttccatcc
    31681 acccatgtga gtgtttcctt tgtagccatc aagaacgcga acacggtttt ctttaccttc
    31741 aattttttcc cagttcttgc cttctggacc gtaaacaaga ccgttcaaga gttctggatt
    31801 cgtattcaag aggttcaaga tttccattga tttttctttg ttcttagagt tgtttgagat
    31861 gacaaagtta gcaacttgtg ttgtttggtt tttcttgatg aagttagtaa ttggtttgat
    31921 ttggatatct ttgttggcaa cacgtgaaag caagctgtta ccgtagtcag ctggtcctac
    31981 tgtttcttca cgaacgaacc aagtatcttg ttgaaggtca aaggaagtat cgcttgttgc
    32041 gacatctttt ggaatgtagc cagcttcata gaatttgtga agagtcttca agtgttcttt
    32101 gaaacgaggc acttcgtaac ggtttacaac tttagtagta tcgccttcaa ggtcaataac
    32161 gaatggaagc ccgtttgcta ctgggtagtc aaagttatca gatgggatga aaactttacc
    32221 aatagcaaat ggtactacgt ctggagcttt ttctttaatt tgtttcaaga ctggctcaag
    32281 agtttcgtaa gaagtaacac ctgaaatatc gataccatat ttggcaagga gagttccgtt
    32341 gaaggcaaag ttttgagatg atgcaacgtt ggctgcaact ggaacagcgt aaattttacc
    32401 gtttacagta ttacccttga tgtaagctgg gtcaagtgcc ttgtaaaggt ctttaccttc
    32461 ttttttgtac aattctgtca agtcagcata agcacctttt tgagcattta caatatagtt
    32521 atctgcaaag gcgatatcat agttttcacc agatgatgtg ataactgaca ttttcttacc
    32581 atagtcaccc cagccaaggt attggatatc caatttagca ccaacttttt cttcgatgat
    32641 tttgttggca tttgctaaca attcatccaa gttatctggt ttgtcaccga tttggtacat
    32701 tttgataaca ggtttgtcac ctgaatcagc agcttttttg ctgttacctg tcaagttgcc
    32761 acaagcagca agacctgcag ccagagcgac tacactagca gatgcaaaag catatttttt
    32821 ccagtttttc atgataaaaa ctcctttttt tatttttaaa cttataaaca atgtaatgat
    32881 cttatactca atgaaaatca aagagcaaac tagaaaacta gccgcaggct gctcaaagca
    32941 ctgttttgag gttgtagata agactgacga agtcagttac atatatctac ggcaaggcga
    33001 cgttgacgcg gtttgaattt gattttcgaa gagtattaac ttcacacaag ggaagttggg
    33061 aactgagaaa tgttcttttt caataagcac tattctttca caccaccgat agtcaaacct
    33121 tttacaaagt agcgttggaa gaatggatat aaaatcgcga ttggaagggt tgcaaccaca
    33181 accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc agtcaagccg
    33241 accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata ttgcaatgga
    33301 tacaagttat cactcttgat gtaaagaagg gcgttgaacc agtcattcca gaaaccaaga
    33361 gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca gatttggaag
    33421 aaaatccggg cctcactggc accatcgata cgagccgatt cgagaatggc ttctggaatg
    33481 gtcttcttga agaaggaacg catcaagatg atattgaatg gtgagagaag cattggaaca
    33541 atcaaggccc aaacagtgtc cccaagctga agtacacggg tcaccatgat ataacctggt
    33601 accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa tctgcgatac
    33661 ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac atttgtcaat
    33721 gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt atccttaaac
    33781 tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct atagccgtat
    33841 tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa aggtaggata
    33901 caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt cttactgaag
    33961 gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc catattctcc
    34021 tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt ttgataggat
    34081 aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca taccgatatc
    34141 tgctgtctga gtcaaaccat taaagacata tacgtccaaa acgttggtta cattgtaaag
    34201 ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga agatatttcc
    34261 gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg ttacgttgcg
    34321 aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg ttggatcaat
    34381 tcccatgatc gtcgcatagt acatgacact gctatatcca aatcctttcc aaatacctag
    34441 gaaaagtagg agatagggcc agatgcccag gtcagcgtag aaattgactt ctttgagacc
    34501 aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg catctgtaaa
    34561 gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt gaaaaatctt
    34621 caccattctc ttagaacgga gctcgctgag gataatggcg atccctacag atacaactaa
    34681 acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa taaaggcgtc
    34741 tcttgaacta aataagaatc taaaattatc gagtccgacc catttactat ttatgatact
    34801 atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt tcccaaatac
    34861 tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca agagaaagat
    34921 ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt ttattttgat
    34981 atccatctaa aaattctttt ttagactttt gataacgatt acattattag tatactccta
    35041 tttgcaggtt aggttaaact cctaattata gaaaaaactc cacaaattat gtagcagatt
    35101 taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt ttatctctat
    35161 tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata ctgaaaaatc
    35221 tccagactag ggaactcagc gatagttcct aatctggaga tttttaatat gttattaggc
    35281 gtttgctttc aacttagcaa taacctcttt aagattatca atcaactctg ctgcagtatg
    35341 ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt tttgagagtt
    35401 ttcaaggaca tccttatcta ctgtttcaag gtttgagtct ttaagaagtt tacttaattc
    35461 cttggctaat ttcttgagtt tgatttgcag actcatcttc tcctgctgtt tctttgcccg
    35521 ctgtttgtcc tccatcctta gttgctgact ggctttcctt aatggactct agggaagcaa
    35581 tggcatcttt gactgtttgc aagatatcac gtaaaccttg ctctgtcaaa ctatcatctg
    35641 taagagcttt cttagcctct gccaaaacca gacgtgctga atctgtggta ggattcgata
    35701 cacctgtcaa tgatctcaaa agattttcta aggtttgagt ctgcttacta atactagact
    35761 aaaatcaaaa agcattacat aacagtgata tgaaatcaac taaagaagaa atccaaacca
    35821 tcaaaacact tttaaaagac tctcgtacag ctaaatatca taaacgcctt caaatcgttc
    35881 tatagtaaaa tgaaacaaga acaggacaaa tcgatcagga cagtcaaatc gatttctaac
    35941 aatgttttag aagtagatgt gtactgttct agtttcaatc cattatattt cgtctgatgg
    36001 gcaaatctta taaagagatt atagaacttt tatagtagtt tgaaataaga tgtgaacaac
    36061 tctatcagga aagtcaaatt aatttataga aatattttag cagccaaggt gtactgttat
    36121 agattcaata cactatactt ggtggtttag ctctcctgtt ttctctttta gctttaacca
    36181 gccataaatg gtattacgtg agatttggaa aacgtgtgat gcttctgtta tactacctgt
    36241 tcgctcacaa taagagagaa cttttttacg aaaatctatt gaatatgcca taaaaagatt
    36301 ataccacatt gtgtactatt tttggttcac tttactatat cactttggac tatatcggtc
    36361 tagttatgtc taaacgatta tagctggata ctaagagaaa tcaaaaaagc actaagggag
    36421 aacgtcccaa agtgcttaat atcaaggcct caaagcctat cttatttaat aaaatattac
    36481 aacattttgt tgtagaattc aacgacaagt gcttcgttga tttctgggtt gatttcgtcg
    36541 cgttctggca agcgagtcaa tgaaccttcc aacttttcag cgtcgaatga tacgaatgct
    36601 ggacgtccaa gagtagcttc tactgcttca aggattgctg gaactttcaa tgatttttca
    36661 cgaactgaga tcacttgacc tggagttacg cggtatgatg ggatatcaac gcgtttcccg
    36721 tcaacaagga tgtgaccgtg gtttacgaat tgacgagctt gacgacgagt agtcgcgaga
    36781 ccaagacggt aaacaacatt atccaaacga cgttccaaaa gaagcataaa gttgaaacct
    36841 aggattccac ctttgatttt tgtagcttgt acgaacaagt tacggaattg tttttcacct
    36901 acaccgtaag tgaaacgaag tttttgtttt tcagccaatt gcaaaccata ttctgacaat
    36961 ttagaacggt tgtttggtcc gtgttgtcct ggtacatagt tacgacgtgc caattcttta
    37021 cctgtacctg taagtgaaag gccaaggcga cgagcttgtt tccaagatgg tcctgtataa
    37081 cgtgacatat gaatgtcctc ctgatataaa taatatttcg gtggaaatag tcacttagaa
    37141 agccctgatt cgtgcagatg cccttcgcct aaacagccaa ggttacttgt cataagacac
    37201 ctgttgacga gcttcatgct ttcctgctga tatttcacac taaattcatt ttaccatgaa
    37261 tagctggatt tgtaaagggg ttttaggctt tattttcact accagagagg ttgagaacga
    37321 gggtaaaggt acttcctaga ccgtactggc tgctgactgt gatttcccca cccaattgat
    37381 gggccaattc acgcgcaatc gcaagtccta atccatgacc acctgtcttc atgttacgcg
    37441 aagtttcgac acgataaagg cgtttgaaaa tattttccaa atcctctggg gcaataccct
    37501 gcccttcatc ggtcacactg attgaaagct ggtccttctc cagcttagcc accacttcca
    37561 gcttggttcc tggagcagaa tatttaaaag cgttatcgac cagattcacc aagatacgag
    37621 aaagcttagc ataatctccc tcaatccggg cagactctgg gattacctgc aagtggacat
    37681 ctcttctctc ctgctcaatc aaaaactgaa attcactcat gcactcaatt aagagcttgt
    37741 ccagaaaaat actgtcttta ctggtagttt ccacctgatt tctagctgtg tttagggtca
    37801 aaaaattcaa ctcctcaacc agtttattga gcctctccgt ctggcgtcca atggttgcta
    37861 gataatgagc ttgctccgac tccttgataa taccatccaa aatcccttct accgtcgctt
    37921 ggatcgaagt gataggagtc ttaatatcat gcgacaactg ggcaatcatc aagccctttt
    37981 ctcgttcgct ttcttccaag gaatcaaagc ttacctgcaa atcatgggac atctcattaa
    38041 aagtttgccc taattgctga aattctacag gaccttgaac ctccaaattt gaaggaaaat
    38101 ccttggccgc tacccgcttg gcatgctcct tgagtttgcc caacgacgta aagactggca
    38161 ataggagaaa gagactaatc ccagcaccga caaggctggc aacgatggtc atcccaagca
    38221 aaaagtaaat ctcgcctttc gcaatcagca ttttttgaac agcccaaaaa acaaccaaaa
    38281 tggttaagag ggttgaaata atatatccaa ccaaaatata actttttagt ttcatgtttg
    38341 tcctctcggt ttctctatct tatatcccaa cccccaaact gtcttaatag tgggcgtttg
    38401 gtcactacta tattttgcca gctcctgtcg aagagcatgg atatgcacat tcaaggtatt
    38461 ggtgtcatcc acgtagtctt ctttccagat cttttcatag aggtctgtct tggagaaaac
    38521 tcgctctgga ttgctagcta aaatccacag caattcaaat gatttaacag ttaaatccag
    38581 catttcttct cctatttgaa cttcatgact actatgattc atttttagat tgccaaggga
    38641 aatcagctct gtttcgcacc cacgatgaag gcggcgcaaa atattgtgga cacgcaaaac
    38701 tagctcacgt gggctaaaag gcttagcaat aaaatcatct gctcccaagc tcaggccgta
    38761 aatcttgtcc tgttcactgg tcttagcagt aataaatagg aaaggctgct ctggtgataa
    38821 gtattgaacc tcactgatta aatcataacc atccatccga ggcatcatga catctgtgat
    38881 aatcaaatca atcggttttt tcttgaacag ctctagcgct tccagtccat catgggctac
    38941 caagacctga taacctgcct gaattaagta tctctgatga atatctgtga tttctacctc
    39001 gtcgtcaacg agtaaaattg tctttcccat ctgtctctcc tttgataaaa acagtgctat
    39061 actgctttaa gtataacact atttttattg ttttacgatg attttaatct gctattgaaa
    39121 gaaagtcctg attgctgatt gagttgttaa actaatctta gtcagcccac tatccatcat
    39181 ttatttcctt agctgattag ttttcttctt ttttgttttt caaacctaga ccaccgagta
    39241 aacctgcaag cgcaagccca aggaaaccaa tacttgccat tgatgtttga gtctcaccag
    39301 tatttggtag catagcttta tcctctgaca tcatcgtatc agacatcttg ttagcagaag
    39361 cagccatgtt ttcacctgcc atcgtgttgg tagaacttgt catggtgtca gcaggcatgc
    39421 tatctgtagt acctgtagca tgattgtgat tcatcggagt cacgccagaa ccagagttag
    39481 aaggtgataa tgaaccattt gctgtgtctg atgtttcttt aacatttatc ttaatagtga
    39541 cttttttagt tgctacgatg ttgtccaagt ctggtttacc gtctttgtta ccatagacat
    39601 tgactgtagc gctgtaagtt tgagt
//
LOCUS       DBERCW010000018        39415 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.018, whole genome shotgun sequence.
ACCESSION   DBERCW010000018 DBERCW010000000
VERSION     DBERCW010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.018"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..283
                     /gene="tnpA"
                     /locus_tag="ACL72M_001127"
                     /pseudo
     CDS             1..283
                     /gene="tnpA"
                     /locus_tag="ACL72M_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            465..527
                     /locus_tag="ACL72M_001128"
                     /pseudo
     CDS             465..527
                     /locus_tag="ACL72M_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(671..1300)
                     /locus_tag="ACL72M_001129"
     CDS             complement(671..1300)
                     /locus_tag="ACL72M_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGS0716261.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(1310..2311)
                     /locus_tag="ACL72M_001130"
     CDS             complement(1310..2311)
                     /locus_tag="ACL72M_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGS0716262.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(2342..2983)
                     /locus_tag="ACL72M_001131"
     CDS             complement(2342..2983)
                     /locus_tag="ACL72M_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGS0716263.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(3002..3817)
                     /locus_tag="ACL72M_001132"
     CDS             complement(3002..3817)
                     /locus_tag="ACL72M_001132"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGS0716264.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            4088..4522
                     /locus_tag="ACL72M_001133"
     CDS             4088..4522
                     /locus_tag="ACL72M_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0716265.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQESVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            4534..5724
                     /locus_tag="ACL72M_001134"
     CDS             4534..5724
                     /locus_tag="ACL72M_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGS0716266.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            5735..6226
                     /locus_tag="ACL72M_001135"
     CDS             5735..6226
                     /locus_tag="ACL72M_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0716267.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            6241..7020
                     /locus_tag="ACL72M_001136"
     CDS             6241..7020
                     /locus_tag="ACL72M_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS0716268.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            7007..7825
                     /locus_tag="ACL72M_001137"
     CDS             7007..7825
                     /locus_tag="ACL72M_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0716269.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGENQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            7825..8118
                     /gene="yajC"
                     /locus_tag="ACL72M_001138"
     CDS             7825..8118
                     /gene="yajC"
                     /locus_tag="ACL72M_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS0716270.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            8140..10041
                     /locus_tag="ACL72M_001139"
     CDS             8140..10041
                     /locus_tag="ACL72M_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGS0716271.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFMSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            10101..11102
                     /locus_tag="ACL72M_001140"
     CDS             10101..11102
                     /locus_tag="ACL72M_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0716272.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(11212..11547)
                     /locus_tag="ACL72M_001141"
     CDS             complement(11212..11547)
                     /locus_tag="ACL72M_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716273.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(11558..11800)
                     /locus_tag="ACL72M_001142"
     CDS             complement(11558..11800)
                     /locus_tag="ACL72M_001142"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716274.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(11816..12010)
                     /locus_tag="ACL72M_001143"
     CDS             complement(11816..12010)
                     /locus_tag="ACL72M_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0716275.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            12176..13126
                     /gene="rsmH"
                     /locus_tag="ACL72M_001144"
     CDS             12176..13126
                     /gene="rsmH"
                     /locus_tag="ACL72M_001144"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGS0716276.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPEGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            13138..13455
                     /gene="ftsL"
                     /locus_tag="ACL72M_001145"
     CDS             13138..13455
                     /gene="ftsL"
                     /locus_tag="ACL72M_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGS0716277.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            13459..15711
                     /gene="pbp2X"
                     /locus_tag="ACL72M_001146"
                     /gene_synonym="pbpX"
     CDS             13459..15711
                     /gene="pbp2X"
                     /locus_tag="ACL72M_001146"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGS0716278.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            15713..16693
                     /gene="mraY"
                     /locus_tag="ACL72M_001147"
     CDS             15713..16693
                     /gene="mraY"
                     /locus_tag="ACL72M_001147"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGS0716279.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            17257..19362
                     /locus_tag="ACL72M_001148"
     CDS             17257..19362
                     /locus_tag="ACL72M_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGS0716280.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(19658..20140)
                     /locus_tag="ACL72M_001149"
     CDS             complement(19658..20140)
                     /locus_tag="ACL72M_001149"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGS0716281.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(20235..21719)
                     /locus_tag="ACL72M_001150"
     CDS             complement(20235..21719)
                     /locus_tag="ACL72M_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGS0716282.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDATRAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            21872..23482
                     /locus_tag="ACL72M_001151"
     CDS             21872..23482
                     /locus_tag="ACL72M_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGS0716283.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVEMTD"
     gene            complement(23626..25022)
                     /locus_tag="ACL72M_001152"
                     /pseudo
     CDS             complement(23626..25022)
                     /locus_tag="ACL72M_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            25200..26645
                     /gene="cps4A"
                     /locus_tag="ACL72M_001153"
     CDS             25200..26645
                     /gene="cps4A"
                     /locus_tag="ACL72M_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGS0716284.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHRKFLFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTDRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            26647..27378
                     /gene="cps4B"
                     /locus_tag="ACL72M_001154"
     CDS             26647..27378
                     /gene="cps4B"
                     /locus_tag="ACL72M_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGS0716285.1"
                     /translation="MIDIHSHIVFDVDDGPKSIEESKALLREAYNQGVRMIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHAGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            27387..28079
                     /gene="cpsC"
                     /locus_tag="ACL72M_001155"
     CDS             27387..28079
                     /gene="cpsC"
                     /locus_tag="ACL72M_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGS0716286.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            28089..28772
                     /gene="cpsD"
                     /locus_tag="ACL72M_001156"
     CDS             28089..28772
                     /gene="cpsD"
                     /locus_tag="ACL72M_001156"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HGS0716287.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARTGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTAIGEVNKRDVQKAKQQLEQTEKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            28788..30155
                     /locus_tag="ACL72M_001157"
     CDS             28788..30155
                     /locus_tag="ACL72M_001157"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS0716288.1"
                     /translation="MDEKGLKIFLAVIQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            30161..30904
                     /locus_tag="ACL72M_001158"
     CDS             30161..30904
                     /locus_tag="ACL72M_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HGS0716289.1"
                     /translation="MNERMQILGVTIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCHEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEILQDMLKVFKQRYPNLNVVGYRNGYFSPEDEKKIQEDIKGGKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQKLNLEWLFRVVN
                     EPKRLFKRYFIGNVTFIKRVLDEKRKSKK"
     gene            30879..31964
                     /locus_tag="ACL72M_001159"
     CDS             30879..31964
                     /locus_tag="ACL72M_001159"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0716290.1"
                     /translation="MKSENQKNNILHISRTMDIGGAERIVYQLSSDLKDEFDSVHVAS
                     TGGLWESKLLSKGVQHHKILDVDSKNPLTMVKILSSFYRIIKNNDITIVHTHHRMAAF
                     YIRLLKIINPKLIHVYTAHNVFKNKLPLYKFSLKKAYCVAVSKAVNDNLKHDVGISDS
                     TVIYNGVVFEKTDKLVGEIVNYNGIKLGCIARLSEQKGLTYLIDAMSLVKHRNITLFI
                     VGDGELRDELENKVKQLNLQKSVIFLGYRKDIVECINSFDYLVSSSLYEGFGLNAIEA
                     FMKGKTMVSSDIPGINEVVNNKNGILVPVKDDVALARAIEKLATDKKLREKLAYQAKK
                     DYETKFNYSLFLDNYRRLYRKLMGESK"
     gene            31961..33049
                     /gene="wecB"
                     /locus_tag="ACL72M_001160"
     CDS             31961..33049
                     /gene="wecB"
                     /locus_tag="ACL72M_001160"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HGS0716291.1"
                     /translation="MKKVMLVFGTRPEAIKMCPLVNELKQNDSIKTLVCVTGQHKEML
                     EQVLEVFKVVPDYDLGIMKANQTLFTITTSILDKIQAVLEKEKPDLVLVHGDTTTTFA
                     TALAAFYMGIKVGHVEAGLRTYNLQSPFPEEFNRQTTSIIADYHFAPTEVAKENLLRE
                     DRKNIFVTGNTVIDALKTTVQDNYHHPILEWAKGSKLIMLTAHRRENLGKPMENMFNA
                     VNRILNEFEDVKVVYPIHKNPKVRELASKVFGDNERMKIIEPLEVIDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVVAGTLKLVGTEEENIYSNFKLLLEDET
                     EYNKMSKASNPYGDGMTCKRIVDIILEV"
     gene            33166..34230
                     /locus_tag="ACL72M_001161"
     CDS             33166..34230
                     /locus_tag="ACL72M_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGS0716292.1"
                     /translation="MATLFALLSTLVKLFVTFDYIPKVLLQHKVTLIDILVVLFLFFQ
                     AFAAFQSQTLYLNYVGGQFFLLGLYSFLKHFLLLDCKTTIKSLFLTFILFLCVQVITQ
                     LLFPVGFDSLHPTGDNRLYFLGRKNIATPYIIVGLGGFYLLNKKMNEFISLKEIIFLG
                     LFGILSFLTQSSTAIICYGLFIFIRLLGLKENIGKLYSLVSMAVYVCFSLSIIFSQST
                     ILSTFTAIFSKNATFSGRINIWQLAIRIFEENFWFGRGLNVNFNAWTNGIIVNSAHNT
                     LLDILARTGIFPGVLFIVLLMNLFLGKYRIESKTLLAMLASFMIYITMETSSMSILLL
                     IIVLCVYWPRGEEKLHEQVT"
     gene            34214..35083
                     /locus_tag="ACL72M_001162"
     CDS             34214..35083
                     /locus_tag="ACL72M_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HGS0716293.1"
                     /translation="MSKLLNTIYYRLFRLYKKIYLQVFSKKTVDILGEKANLENELIV
                     SFTTIPSRLNYLPSMIKSIFNQTIIPNRFIMYVYKDEFEGINLESILELEIKNGLEIV
                     YVDENLRSHKKYFYAMKDNPNSIVVLVDDDIIYPRNTIKKLIASYRIYPQCVSAMRCH
                     RIKLFSDGSLYPYNQWEYEISGATIPSYFNFFTSGGGTLFPPCTRNEDLFNKKNIREL
                     SFLADDVWLNFLVVKNGIKTVKATRYKGTPLTIDDNPEESLVYLNTVYDNNNDKCIRN
                     MVEYYQINFTEDK"
     gene            35083..36507
                     /locus_tag="ACL72M_001163"
     CDS             35083..36507
                     /locus_tag="ACL72M_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HGS0716294.1"
                     /translation="MNVEKNLKRGIFYTAIGKYSNVVIQLLVTAILSRILSPVEYGIV
                     AVVNVFLLFFQMLADSGIGPAIVQNKELNKSDLISIFSLTIYSGIVLSCIFALLGYPM
                     GVLYGETIYVSLFPLLGLCVLFYTITIVPQAILMKTMNFKIVNFLTIFSNIASGLVGV
                     ILAVSHFGVYSLIFSNIVKAMVLFIALYSKAKINFYWKVSKSSIGKIFEFSKFQFLFN
                     FWNYFARNLDNLLIGRLISPSDLGYYDKAYQLSLYPNQILSQVVTPALHPIMSNFQDN
                     ISKIGEVYLQISRIFVIVGIPISAYLYFNAQYVVTFMFGDNWSQSVPVFQILAATIWL
                     QMANSPTGAFYQATNQTKLLFRIGLLTSFINILAIVIGVMLQSIQCVAYMLLISFSLS
                     LVINTLYLTKKVLNISAQKYIKPILINLTIISPYIVFNLFISDFVNDLILHLSVQFVI
                     LFLIWGIGMYISGEYRRVFAVIRK"
     gene            36520..37722
                     /locus_tag="ACL72M_001164"
     CDS             36520..37722
                     /locus_tag="ACL72M_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0716295.1"
                     /translation="MKILFVNMFYNEAGGAQKSTKFLAEQLVKEGHEVFAYSDDAIDS
                     DIDEVINRVKIFRRRTPLFSLHYIFSAKKNPAKHFFYKIFETYNVFAKRKFINIIEEV
                     QPDIVHFNTISGMSLSIVKEAKKRNIRTVWTLRDYWLEYPWGEKDISLIKLLNRIYRP
                     FVKKSLRHLDIVTAPSAFTLNNFINKGFINPSSQKCMVIENAVIFSKGKLENIIKQKQ
                     ETKRNPEKTNFLFVGSILEIKGVFNLVKAFKKLTSPEISLKIVGKGKDLEKLQKEIES
                     DPRIQYLGFQDTETLYKTYQNSDVLVVPSAWDEPFGRVVIEGNANGLPVITSDRGGLP
                     EIVQTVGGGEIFTDESGNTLYSLLKKFVEMENYNVYYQCILENIDIYSIEKQSEKFTN
                     LYLDKEIE"
     gene            37756..38988
                     /locus_tag="ACL72M_001165"
     CDS             37756..38988
                     /locus_tag="ACL72M_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGS0716296.1"
                     /translation="MKIAVAGTGYVGLSIAVLLAQHHEIKAVDIVAEKVELINQKKSP
                     IQDDYIEKYLVEKDLNLEATMDAKYAYEDAEFVVVAAPTNYDSKKNFFDTSAVEAVIQ
                     QVKKINPKAVIIIKSTIPVGFTESVQKKYQYKNILFSPEFLRESKALYDNLYPSRIIV
                     GTDLEDTYLKDKANIFASLLKEGAIKEDIDTLFMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDAKAIIDGIGLDPRIGNHYNNPSFGYGGYCLPKDSKQLLANYFDVPQ
                     NMMTATVESNRTRKDFIAQRILEKAGVSETDSLDAFKNIQDIVIGIYRLTMKSNSDNF
                     RHSSIQGVMKRLKAKGVTVIIYEPTLKDGETFFGNKVVNNLDKFKEASNVIVANRFEP
                     SLEDVSNKVYSRDIFKRD"
     gene            39207..39386
                     /locus_tag="ACL72M_001166"
                     /pseudo
     CDS             39207..39386
                     /locus_tag="ACL72M_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        12221 a         6559 c         8425 g        12210 t
ORIGIN      
        1 tcaatataga agtagtttag gcgaaatatt tcatcgcttg tgtagttata aaggtgttga
       61 aatgatcgag ggtcacttaa tgccagacca tgtacacatg ttagtcagta ttccactaag
      121 gctaagtgtt tcgagtttca tgggttattt aaaaggcaaa agtgcactca tgatgtttga
      181 caaacacgcc aatctcaagt acaagtttgg gaatcggcat ttctgggcgg aaggttatta
      241 tgtaagtcca gtagggctta atgaagacac aattaagaaa tatagtcaag attaaagaaa
      301 ttatcgagtg gatgatttct tcacgagtat gaaaatttga gaactagtaa agtatgatat
      361 atagtaaaat gaaataagaa caggacaaaa tcgatcagga cagtcaaatc gatttttaac
      421 aatgttttag aagtagaggt gtactattcc agtttcaatc tactatagca ctagataaat
      481 tgagtgtaaa agaatatgag gatcccttta gggatagtgg taagtaatac caaagtctct
      541 taaagaggca agtgacgagt caagagcaat aaggcttgaa caacgtgaaa gccagcgtct
      601 ttaggcgctg gctgatgatt tgggcttata gctctgagat aaaccacccg ttagacgggt
      661 agttatgatt ttatctgagt gtaacatact gttgggcaat ctcgctgatg cggtcaaagt
      721 tgccttggga agcgagttta ttgagttcgc caccaattcc aacggcatct gcaccagcag
      781 cgaaccattg agggatgttg tttagaccga ctcctccggt taccattacg gaaacttgtg
      841 gaatcggtgc cttgactgca gagatatatg ctggactgag agtactacct gggaagagtt
      901 tgatgatttc actaccggct tcaagtgcag tcgtgatctc tgtgagggta atacagcctg
      961 gaatgtacgg tgtgctgtag agattgcaca ttttcgcagt ttcagcatgg aaagatggag
     1021 aaacaacgta atttgctccg gctagaatgg catctctagc agttacggca tcaagcacag
     1081 tacctgcacc gatacaaaca ctctgatcgt cctgatacaa gtctacaagt tccttgatga
     1141 tttgtcctgc atactgattg gtataggcga tttcaatagc tttgataccg cccttgatac
     1201 aagcaatcga ggcttgtagt ccttcttcct ttgtatttcc tcgaatgaca gcaacaattt
     1261 tctgtttttt tagttcaata attgtatctg atttggtcat gtaattctcc taacgaatga
     1321 tatcttgtgc atttgccagt aaattttcaa tactagttgc ggaagtggag agatggtctc
     1381 ctggaagagt gcatttgaga gttgcgctcg caactgcaaa gtcaatggta gtttttaggg
     1441 aggaatgatg gagtagttgg taaagggcac cagatataaa ggcatccccg ctaccaattc
     1501 gttgatagac tgcagttttt agttggacag actcttcaaa tcgttcttcc agagcatagg
     1561 cttgatagac atttttgtct tgctcatcac tagagcggag ggtatggaaa atggccttga
     1621 aaccataggc ttcttttaaa agtcgcatgc gattttccac ctcttctagg ctagcactgt
     1681 ctcttggaaa catctctaga ttttggtcat caatcatgag aggatcaata ccgaagcaat
     1741 agtcagtaaa acgtgcaaac ttagaaaatt catacttggc ttctaggact gaaatcatct
     1801 ttgttctcag attgagatcc attgaaacga caattcctcg gcgcttggct tcttccaaga
     1861 gtaggagaag gatcgcacgg acctcttgac cgatagctac ggtgattcca ctaaaatgaa
     1921 aatggctaat cccctgaaag agagaatcca tatctagcat gtttggccga atctggctga
     1981 tactcgtatg cttacgatcg tagaaaactt cactttgacg acaaccaaag ccgttctcca
     2041 aatagtagag gccgattcga tcgccaagcc gacagattga actggtatcg atttggtgct
     2101 gtttcaagaa tgtgagaaaa cgatctccaa tctcgttggc agggagtgcg gtaaagactt
     2161 tcgttgagat acccagggct tgcaaattac aagcgatgtt aatttctgat ccgccaaaat
     2221 aagtcgaact ggcaacatga tctccgatac tggtggcatc taatggtgag attcgaatta
     2281 atggttcgcc aaacagtaat attttcgtca tccattagtt cctttctggt ttagaatagc
     2341 tttacttggc taatacttct ttcaaataag cagcgacttc atcatcttgg cagttttcaa
     2401 agaagtattc ttggaagtat ttgccagata tggtgtcttt gaggaagtct tggtcgattg
     2461 ttttaaggat ggtcatcaaa tcattgtggg tgatttgttt cacctcgttt aagatacgag
     2521 cgttgcgttg ttcagggatt acacgttctc ttgggtagcc accgcccatt tcttcagcaa
     2581 ataagcgttc aaacatcaat ttgagggtca gttctgcccc ccagccaaat cctttggcat
     2641 aagggataga caaggcgtta ccaccattga tttgagaata aaggtaagcg tcagttgggt
     2701 ccactgctag accacagaca acaccaggga agctgtttaa agcaagcata gcccctacac
     2761 ccgtaccaca gccggtaaca acaaagtcaa ctgcctttgt atttaaaagg atggcagcca
     2821 ttagtccgtt ctgcacataa gttaattgac tttctccttc ttctccacgc ataccatagt
     2881 taaataattg gtagtctttt ttatctgtcg cttcttttag actatcgtaa ataatgtgat
     2941 tcttgctagc ttgactattt tcattgatta atgcgatttt cataagatct tctttctatt
     3001 tttactcagg ttgttttccg atgtaggcta agataccgcc atctacatat aggatgtggc
     3061 cattgacaaa attgctggca tcactagcga gaaagacagc agggcccatc aaatcttcag
     3121 gatttcccca acgtgcagca ggtgtttttg caatgatgaa ctggtcaaat gggtggcgag
     3181 aaccatcttc ttgcaactca cgaagaggtg ctgtttgagg agtggcaata taacccggtc
     3241 caattccgtt acattggata ttggctccac cgtattcaga cgcaatgttg cgggtcaaca
     3301 ttttcaagcc ccctttagca gcagcataag cgctaactgt ttcacgtccc agttcgctca
     3361 tcatcgaaca aatattgata atctttccat gccctttctt tatcatagaa ggaataactg
     3421 cctttgaaac gataaatggt gcgtttaagt caatatcgat gaccttacgg aaatcagcgg
     3481 cgctcatttc gcacattgga actcggcgga taataccagc gttattaacg aggatgtcaa
     3541 tgacaccaac ctcttgttcg atttgcttga ccatggcttg gataccgtcc tcgtctgtca
     3601 cgtcacagac atatccatgg gcttcgatgc caacttcacg ataagcttca atccctttat
     3661 tgaccagatc ttgattgata tcgttaaaga caatagtagc gccggcttca gcgtaggatt
     3721 tggcaatagc aaatccaatt ccataagaag cgccggtgat gagagcaatt tttcctttta
     3781 aagaaaactg ctcaattgag aatgatgtat ttgtcatttg atgcttcctt tcaaatttgt
     3841 taagacttct ctataaccaa attatattct agtaaaccgg ttttgtcaat aaataaatat
     3901 ttttatttat aaaaagattt attttcctta aaaatggaat attttgaaat ttctgtctat
     3961 taaaatggtt aaaaagataa tgaaagcgct aatatttttt taaaaaaact attgacaaga
     4021 taaaaataaa ggattacaat ggggaatata aagtaaaccg gtaaacttaa acaagaaagg
     4081 agaaaagatg aaaattgtac ttgtagggca tggacatttt gctacaggga tttatagttc
     4141 tttacaattg attgcaggca atcaagaaag tgtggaggcg attgactttg tggaaggaat
     4201 gtcagcagat gaactcaagc aaaaaatctt acttgcaatt tcaaatgaag aagaagtttt
     4261 aatcctaagt gatctcttgg gaggatcgcc attcaaggtt tcttctacca taatgggaga
     4321 aaatccagcc aaaacaatga atgttctctc gggtttgaac ttagccatgt taatggaagc
     4381 agtctttgct agaatggctc atagctttga tgaggttgtt aataaatcag tagtggcggc
     4441 ccagggcgga gtcgtaaatg gtaaagaatt gttttcaacg gatgcagagg aagaggaaga
     4501 agatttcgaa tcgggtattt aaagggtaaa agaatgataa aaaaggttac gattgaaaaa
     4561 ataaaatcgc ctgagcgctt cttagaagta ccacttctga cgaaagaaga agtcggccag
     4621 gcaatcgata aggttattcg gcagttagaa ctcaaccttg actatttcaa ggaagatttc
     4681 cctacgccag ctacctttga taatgtctat ccaatcatgg ataacacgga atggaccaat
     4741 ggtttctgga caggagaact gtggttggct tatgaataca gtcaacagga tgcatttaaa
     4801 aacatcgctc ataaaaatgt tctttctttc ctggatcgtg tcaataagag agtagaattg
     4861 gatcaccatg atctcggctt cttgtacaca ccgtcttgta tggctgaata taagataaat
     4921 ggagatggag aggctagaga agcaaccttg aaagctgcag ataagttgat tgaacgctat
     4981 caagaaaaag gtggttttat tcaagcttgg ggagacttgg gcaagaaaga gcattaccgt
     5041 ttgattatcg actgcttgct caatatccaa ctcttattct ttgcttatca agaaacaggc
     5101 gatcaaaaat actacgatat tgcagaaagt catttctatg cttcagctaa taatgtaatc
     5161 cgtgatgacg cttcgtcctt ccacaccttc tattttgatc ctgagacagg tcaacccttt
     5221 aaaggtgtaa cgagacaagg gtatagtgat gattcatgct gggcacgtgg tcaatcatgg
     5281 ggagtctatg gtattccttt gacttatcgt cacttaaaag acgagtcctg ctttgacttg
     5341 tttaagggtg tgaccaatta tttcttgaat cgtctgccaa aagatcatgt gtcctattgg
     5401 gatttgattt ttaatgatgg tagtgatcaa tcacgagatt cttcagcaac agctatcgcc
     5461 gtctgtggga ttcatgaaat gctaaaacat ctcccagagg tggatgctga caaagatatt
     5521 tataaacatg ctatgcatgc catgcttcgt tccttgatcg aacattatgc aaatgatcaa
     5581 tttacccctg gtgggacaag tctcctccac ggtgtgtact catggcattc aggtaaagga
     5641 gtggatgaag gcaatatctg gggtgactac tattacctag aagcccttat ccgtttctac
     5701 aaagactgga acctatattg gtaggaggag aaatatgaca atgccaaata ttattatgac
     5761 ccgtatcgat gaacggttga ttcatggaca aggacaactt tgggtaaaat acctaggttg
     5821 taatacggtc attgttgcca atgacgaagt aagcacggac aagatgcaac aaactctgat
     5881 gaaaacagtt gtgccagact cagttgccat gcgtttcttc cctttgcaaa aggtgattga
     5941 tatcattcac aaggctaatc ctgctcaaac gatctttatc gttgtaaagg atgtgaagga
     6001 cgctttaacc ttggtagaag gtggtgtccc tatcaaagaa atcaatattg ggaacattca
     6061 caatgctact ggtaaagagc aagtgacacg ctccatcttc ctgggtgaag aggacaaggc
     6121 agccctcaag gaattaagcc aaactcatca agtaacattt aatacgaaaa caactccaac
     6181 aggaaatgat ggagctgttc aagtcaacat tatggactat atttaaaaga ggagatcgtt
     6241 atgtcgatta atgtatttca agcgatttta attggattat ggacagcttt ctgttttagt
     6301 ggaatgctat taggaattta caccaataga tgtattgttc tgtcatttgg tgtcggaatt
     6361 attctaggtg atctgcctac tgctcttgca atgggagcta ttggtgaatt ggcttatatg
     6421 ggattcggtg ttggtgctgg aggtactgtt ccaccaaacc caatcggacc tggtatcttt
     6481 ggtaccttga tggctatcac tagtgctggt aaagtcagtc cagaagcggc tcttgccctc
     6541 tctactccga ttgctgtggc gattcaattc ttacaaactt tcgcctacac tgtacgtgct
     6601 ggtgcgcctg aaacggcgat gaagcacttg aaaaaccata atttgaagaa attcaagttc
     6661 actctaaatg caacaatttg gttgtttgcc tttattggat ttaccttggg ttgcttgggt
     6721 gccctttcaa tggatacctt gttgaaactc gtagactaca ttccaccggt attgcttaca
     6781 ggtttgacag ttgctggtaa aatgctccca gctatcggtt ttgcgatgat cttgtcagtg
     6841 atggctaaga aagagttgat tccctttgtc ttgttgggat atgtttgtgc agcttatcta
     6901 aacatcccaa caattggtat tgcaattgta ggtactatct ttgctttgat tgaattttat
     6961 aacaagccaa aaacagcgga tcatgtggta gaggaggaag cacacgatga ctggatctaa
     7021 caaattaaca aaacgtgatt atcttaaaac gtctttgcgg gcattctttt gtcaaaatgg
     7081 atttaactat agtaactatc aagggttggg atatgccaat gtgatgtatc ctgctttgaa
     7141 aaaacactat ggagagaatc aggaaggttt ctaccaagcc ttggaagaaa actgtgaatt
     7201 ctataatacc aacccacact tcctgccttt tattaccagc ttgcatcttg taatgttgga
     7261 aaatggccgt ccggcaaaag aaacacgtag catcaagatg gccttgatgg gaccattagc
     7321 aggtattggg gattctctct ctcaattctg tttagctcca ttgttctcaa ccatcgcagc
     7381 ttcgtttgct caagaaggct tggttgtcgg tccaatcttg ttcttccttg cgatgaatac
     7441 gattttaaca gcgattaaat tgtcaactgg tctgtatgga tacaaactag gaacgactgt
     7501 gattgataaa ctaagcgagc agatggcaac gatttctcgt attgccaata ttattggtgt
     7561 aaccgtaatt gctggtttgg cagcgacatc tgttaagatt atggtaccga tcacctttgc
     7621 tgcaggggaa gttaaagcag acgctaaaca aagtatcgta agtattcagg gaatgcttga
     7681 taaggttgct ccagctcttc taccagccct atttacactt ttagtttact acttgatcaa
     7741 agaaaagaaa tggacaacat ataaactcgt tattttaaca gttatcatcg gaattatcgg
     7801 aagctggctt aagattatag cttaatggat acaacattgt tttatggaat agtgattgtc
     7861 ttggcagtga gtcccctttt actgtcaagc tttcattcta ttcgtcagca aaagttgctt
     7921 cgcaaacaga tggagcaacg acaagagtat ttagcttctt taacatctgg tgatgaagtg
     7981 ttgttattgt ctggaattca tggaaaaatc atttctatcc aagatgactt ggtctccttg
     8041 cagattgcaa aaggtgtggt catctatgta gaaaaggaaa gtgtaatggg aaagacaaaa
     8101 gaactgcttt ttaagtagtt ctttttctgg taatagataa tgaaagaaga aagaagacaa
     8161 ttttttgaaa gaatcgatgg aaaccaatgt cgtgattata tcttgtccca ctgttcaaaa
     8221 gactatgaga aagtcaagag ttcccttgaa cgcttgatgg acaatcgttt tatgtttgat
     8281 agtccttggg atatggagcc ttgttcaaaa atccatcaaa tccagccgat ggtatgggat
     8341 caagtatttg aagatgatcc agaatggtct tatatgctca atcgacaaga atatctcttg
     8401 cagtttatga tagggtatgt ggtagaagga gataaggact atattcaaaa gtgcaagttc
     8461 tttctatttg attggattga gcaggtgaga gaattttctc ctcaatcctt gatgactaga
     8521 accttggata ccggtattcg ttcctttact tggttgaaac tactcttgct cctcttgaaa
     8581 tttgacttgc tagaggagaa agaactagag aaaattttgg tcagtctaga aaagcagatt
     8641 gactttatga aaagccacta tcgcgccaag tacaccctta gtaactgggg aattttacaa
     8701 acaattccga tgcttgctat ctatcatttc tttgcagata agatggacct agaagaagct
     8761 taccattttg cttcagagga gttgaaacag caaattgaga cacagatttt aggagatgga
     8821 agccagtttg aacagtcgat tctctatcat gtagaggttt ataaagcctt gctggatttg
     8881 tgtctcttgc ttccagactt gcaagatagt taccaagagt tgctggaaaa gatggcgacc
     8941 tatattcaaa tgatgacagg cttagatgga cgaactttgg cttttggtga tagcgattct
     9001 acagaaacga cagaaatgtt gagcctgtct gctgtggttt tgaacaagga agaccttctt
     9061 aacggtctgg atgttaaagt cgatttgctt agcctcttgt tcctggggcg agaaaaggtc
     9121 aagcgactgc aggaatttga aaagcgagct tggcagccta agttcatgag ctttgaagac
     9181 tctggacatg tctgcattaa ggatgaacat cgttatctat ttttcaaaaa tggtccgcta
     9241 ggaagtgccc atagccatag tgacgagaat agtttttgct tacagtatca aggccaacct
     9301 attttcatag atgctgggcg ttattcttat cgggagatat atgaacgtta tctcttaaag
     9361 agtgcttgga gtcattcgac ctgcattgta gatgggaaag ctccggaaag aatcacggga
     9421 tcctgggaat atgaatacta tcctcactcc ctgttttgtc accataaaga aagggaggga
     9481 atgcattata ttgaaggggc ttattggtca gcagaacctg atttgcctta tcttcacagg
     9541 agaaaaatcc tcatgttggt agaggatgtc tggctcttgg tagatgacat caggtgtcaa
     9601 ggtcagcatg aggcgttgac tcagtttatc cttgacaagg atgtgaccta tcaagatggg
     9661 aaaatcaatc agttgagact atggagtgaa gttgattttg atttggaaga taccatcatt
     9721 tctcctaaat acaatgagct tgaaagaagt agcaaactca ccaagcgcca attctttgag
     9781 aatcagatgc tggattatac catcattgcg catgagagtt ttgaaatcat ccgtcattct
     9841 gtctaccaga cagatgatcg tgaagtggaa aatgctctgg cttttgaagt gaaaaatgac
     9901 gaaacagaca agctgattct gttattaagc gaggatattt gtgtaggtga aaaattgtgc
     9961 ctcgttgacg gaacaaaaat gcgtggaaaa tgtctagtat atgataaaat aaatgagaga
    10021 atgattcgct tgcagtgcta gaaataggca ttttgaatag tgaatatgtt ataataagta
    10081 ttagtaggag gtgttttaga ttggagaaga aactgaccat aaaagacatt gcggaaatgg
    10141 ctcagacctc gaaaacaacc gtgtcatttt acctaaacgg gaaatatgaa aaaatgtccc
    10201 aagagacacg tgaaaagatt gaaaaagtta ttcatgaaac aaattacaaa ccgagcattg
    10261 ttgcgcgtag cttaaactcc aaacgaacaa aattaatcgg tgttttgatt ggtgatatta
    10321 ccaacagttt ctcaaaccaa attgttaagg gaattgagga catcgccagc cagaatggct
    10381 accaggtaat gataggaaat agtaattaca gccaagagag tgaggaccgg tatattgaaa
    10441 gcatgcttct cttgggagta gacggcttta ttattcagcc gacctctaat ttccgaaaat
    10501 attctcgtat catcgatgag aaaaagaaga aaatggtctt ttttgatagt cagctctatg
    10561 aacaccggac tagctgggtt aaaaccaata actatgatgc cgtttatgac atgacccagt
    10621 cctgtatcga aaaaggttat gaacattttc tcttgattac agcggatacg agtcgtttga
    10681 gtactcggat tgagcgggca agtggttttg tggatgcttt aacagatgct aatatgcgtc
    10741 acgccagtct aaccattgaa gataagcata cgaatttgga acaaattaag gaatttttac
    10801 aaaaagaaat cgatcccgat gaaaaaactc tggtatttat ccctaactgt tgggccctac
    10861 ctctagtctt taccgttatc aaagagttga attataactt gccacaagtt gggttgattg
    10921 gttttgacaa tacggagtgg acttgctttt cttctccaag tgtttcgacg ctggttcagc
    10981 cctcctttga ggaaggacaa caggctacaa agattttgat tgatcagatt gaaggccgca
    11041 atcaagaaga aaggcaacaa gtcttggatt gtagtgtgaa ttggaaagag tcgactttct
    11101 aaaatgaagg aaaatgactt gcaatctctg ttaagaaata aaataatccc acctagaaca
    11161 agctaggtgg gattatttgc ctatgaaatg agaaattatg ggagcaagct cctaaatcaa
    11221 ctgtttttga tctacttctt taactacttg ataaaagtta tagaagtagg ccaaacttga
    11281 aatgatggtt acgactagga atattgaaaa tttccattgg acagggttgg ttaaaagttg
    11341 tggaaaggat atgaggagaa agaagagggc tgcgttgagg acaggtatcc gttttgattg
    11401 tattttctca agtcctttat tgagcgcagg aagaaagagg agtaggagta gtaaaactgt
    11461 atgagaaaca gctcctgaaa taagggcaaa gaaaaggaaa atactgataa aaacatgaat
    11521 gatcagtagt ctagctagtg atttcataag gtacctccta atcctggtct tttttagctc
    11581 ttgcaatacg aagtgagtcg acaatatgta tcatcactcc gaaaaagaaa gctcccagta
    11641 tagttttaaa aatatgtttt gtatttagaa gagaactgat aaaatttgga ttttcacttg
    11701 ttagggtatc aatgagtgga attataaaaa atatcactgt tccataaatc gaacctgctt
    11761 tcagaccagg ataacgtaac tgtttctttt cttttttcat gagtttgctc cttttttaaa
    11821 aatcttcctc ccaaaagaga ctgttgaggt cagtttggag gctgcgggcg agattgagac
    11881 agagttccaa ggttggattg tacttgtcgt tttcaatcat attgatagtc tgtctcgaga
    11941 caccgatatc cttggcgagt tcgagctggg aaatacccaa ttccttgcga aattctttca
    12001 cacgattcat ctggtctcct ttctgattta tgtcgtatat atttgactat attatagtct
    12061 tttaaacata aagtgtcaag tatttttgac atattttttg aagaaatagt agtctccttg
    12121 tcctatttgt ctgacaagtg caagctggtc ggatttgtgg taaaatagat aagatatgac
    12181 aaaagaattt catcatgtaa cggtcttact ccacgaaacg attgatatgc ttgacgtaaa
    12241 gcctgaaggt atctacgttg atgcgacttt gggcggagca ggacatagcg agtatttatt
    12301 aagtaaatta agtgaaaaag gccatctcta tgcctttgac caggatcaga atgccattga
    12361 caatgcgcaa aaacgcttgg caccttacat tgagaaggga atggtgacct ttatcaagga
    12421 taacttccgt catttacagg cacgtttgcg cgaagctggt gttcaggaaa ttgatggaat
    12481 ttgttatgac ttgggagtgt ctagtcctca attggaccag cgtgagcgtg gtttttctta
    12541 taaaaaggat gcgccactgg acatgcggat gaatcaggat gctagtctga cagcctatga
    12601 agtggttaat cattatgact atcatgattt ggttcgtatt ttcttcaaat acggtgagga
    12661 taaattctct aaacagattg cgcgtaagat tgagcaagcg cgtgaagtga agccgattga
    12721 gacaacgact gagttagcag agattatcaa gttggtcaaa cctgccaagg aactcaagaa
    12781 gaagggtcat cctgctaagc agattttcca ggctattcga attgaagtca atgatgaact
    12841 gggagcggca gatgagtcca tccagcaggc tatggatatg ttggctctgg atggtagaat
    12901 ttcagtgatt acctttcatt ccttagaaga ccgcttgacc aagcaattgt tcaaggaagc
    12961 ttcaacagtt gaagttccaa aaggcttgcc tttcatccca gatgatctca agcccaagat
    13021 ggaattggtg tcccgtaagc caatcttgcc aagtgcggaa gagttagaag ccaataaccg
    13081 ctcgcactca gccaagttgc gcgtggtcag aaaaattcac aagtaagagg gaaaaagatg
    13141 gcagaaaaaa tggaaaaaac aggtcaaata ctacagatgc aacttaaacg gttttcgcgt
    13201 gtggaaaaag ctttttactt ttccattgct gtaaccactc ttattgtagc cattagtatt
    13261 atttttatgc agaccaagct cttgcaagtg cagaatgatt tgacaaaaat caatgcgcag
    13321 atagaggaaa agaaaaccga attggacgat gccaagcaag aggtcaatga actattacgt
    13381 gcagaacgtt tgaaagaaat tgccaattca cacgatttgc aattaaacaa tgaaaatatt
    13441 agaatagcgg agtaagatat gaagtggaca aaaagagtaa tccgttatgc gaccaaaaat
    13501 cggaaatcgc cggctgaaaa cagacgcaga gttggaaaaa gtctgagttt attatctgtc
    13561 tttgtttttg ccattttttt agtcaatttt gcggtcatta ttgggacagg cactcgcttt
    13621 ggaacagatt tagcgaagga agctaagaag gttcatcaaa ccacccgtac agttcctgcc
    13681 aaacgtggga ctatttatga ccgaaatgga gtcccgattg ctgaggatgc aacctcttat
    13741 aatgtctatg cggtcattga tgagaactat aagtcagcaa cgggtaagat tctttacgta
    13801 gaaaaaacac aatttaacaa ggttgcagag gtctttcata agtatctgga catggaagaa
    13861 tcctatgtaa gagagcaact ctcgcaacct aatctcaagc aagtttcctt tggagcaaag
    13921 ggaaatggga ttacctatgc caatatgatg tctatcaaaa aagaattgga agctgcagag
    13981 gtcaagggga ttgattttac aaccagtccc aatcgtagtt acccaaacgg acaatttgct
    14041 tctagtttta tcggcctagc tcagctccat gaaaatgaag atggaagcaa gagcttgctg
    14101 ggaacctctg gaatggagag ttccttgaac agtattcttg cagggacaga cggcattatt
    14161 acctatgaaa aggatcgtct gggtaatatt gtacccggaa cagaacaagt ttcccaacga
    14221 acgatggacg gtaaggatgt ttatacaacc atttccagcc ccctccagtc ctttatggaa
    14281 acccagatgg atgcttttca agagaaggta aaaggaaagt acatgacagc gactttggtc
    14341 agtgctaaaa caggggaaat tctggcaaca acgcaacgac cgacctttga tgcagataca
    14401 aaagaaggca ttacagagga ctttgtttgg cgtgatatcc tttaccaaag taactatgag
    14461 ccaggttcca ctatgaaagt gatgatgttg gctgctgcta ttgataataa tacctttcca
    14521 ggaggagaag tctttaatag tagtgagtta aaaattgcag atgccacgat tcgagattgg
    14581 gacgttaatg aaggattgac tggtggcaga atgatgactt tttctcaagg ttttgcacac
    14641 tcaagtaacg ttgggatgac cctccttgag caaaagatgg gagatgctac ctggcttgat
    14701 tatcttaatc gttttaaatt tggtgttccg acccgtttcg gtttgacgga tgagtatgct
    14761 ggtcagcttc ctgcggataa tattgtcaac attgcgcaaa gctcatttgg acaagggatt
    14821 tcagtgaccc agacgcaaat gattcgtgcc tttacagcta ttgctaatga cggtgtcatg
    14881 ctggagccta aatttattag tgccatttat gatccaaatg atcaaactgc tcggaaatct
    14941 caaaaagaaa ttgtgggaaa tcctgtttct aaagatgcag ctagtctaac tcggactaac
    15001 atggttttgg tagggacgga tccggtttat ggaaccatgt ataaccacag cacaggcaag
    15061 ccaactgtaa ctgttcctgg gcaaaatgta gccctcaagt ctggtacggc tcagattgct
    15121 gacgagaaaa atggtggtta tctagtcggg gtaaccgact atattttctc ggctgtatcg
    15181 atgagtccgg ctgaaaatcc tgattttatc ttgtatgtga cggtccaaca acctgaacat
    15241 tattcaggta ttcagttggg agaatttgcc aatcctatct tggagcgggc ttcagctatg
    15301 aaagactctc tcaatcttca aacaacagct aaagctttgg agcaagtaag tcaacaaagt
    15361 ccttatccta tgcctagtgt caaggatatt tcacctggtg atttagcaga agaattgcgt
    15421 cgcaatcttg tacaacccat cgttgtggga acaggaacga agattaaaaa cagttctgct
    15481 gaagaaggga agaatcttgc cccgaaccag caagtcctta tcttatctga taaagtagag
    15541 gaagttccgg atatgtatgg ttggacaaag gagactgctg agacccttgc taagtggctc
    15601 aatatagaac ttgaatttca aggttcgggc tctactgtgc agaagcaaga tgttcgtgct
    15661 aacacagcta tcaaggacat taaaaaaatt acattaactt taggagacta atatgtttat
    15721 ttccctcagt gctggaattg tgacattttt actaacttta gtaggaattc cggcctttat
    15781 ccaattttat agaaaggcgc aaattacagg ccagcagatg catgaggatg tcaaacagca
    15841 tcaggcaaaa gctgggactc ctacaatggg aggtttggtt ttcttgatta cttctgtttt
    15901 ggttgctttc tttttcgccc tatttagtag ccaattcagc aataatgtgg gaatgatttt
    15961 gttcatcttg gtcttgtatg gcttggtcgg atttttagat gactttctca aggtctttcg
    16021 taaaatcaat gaggggctta atcctaagca aaaattagct cttcagcttc taggtggagt
    16081 tatcttctat cttttctatg agcgcggtgg cgatatgctt tctgtctttg gttatcaagt
    16141 gcatctaggg attttctata ttgtcttcgc tcttttctgg ctagtcggtt tttcaaacgc
    16201 agtaaacttg acagacggtg ttgacggttt agctagtatt tccgttgtga ttagtttgtc
    16261 tgcctatgga gttattgcct atgtgcaagg tcagatggat attcttctag tgattcttgc
    16321 catgattggt ggtttgctcg gtttcttcat ctttaaccat aagcctgcca aggtctttat
    16381 gggtgatgtg ggaagtttgg ccctaggtgg gatgctggca gctatctcta tggctctcca
    16441 ccaagaatgg actctcttga ttatcggaat tgtatatgtt tttgaaacaa cttctgttat
    16501 gatgcaagtc agttatttca aactgacagg tggtaaacgt attttccgta tgacgcctgt
    16561 acatcaccat tttgagcttg ggggattgtc tggtaaagga aatccttgga gcgagtggaa
    16621 ggttgacttc ttcttttggg gagtgggact tctagcaagt ctcctgaccc tcgcaatttt
    16681 atatttgatg taagaatggc accctgatgt ttcagggtgt ttttgtgttt aaatacacaa
    16741 tgaaaatcaa agaacaaact agaaagctaa ctttaggctg ctcaaaatat agtagattga
    16801 aactagaata gtacacatct acttctaaaa tattgttaga aatcgatttg actgtcctga
    16861 tcgatttgtc ctgttcttat ttcattttaa tatacagttt tgaggttgta gataaggaga
    16921 agctgatgtg gtttgaagag gttttcgaag agtgtaaaaa aatattggtc agttaaagtc
    16981 aaaactcttg accttttctg actaatgtag tatattatga acgtaaggta aatgaaagcc
    17041 ttactagaac acttatttaa agtaaaatag aaagaggtgg gtctatgttt catctagaaa
    17101 tcttcagaag taaagatagt ctactcctgc ttgaaaaaga aaaaccagaa atagtacgta
    17161 gggtagcgat ctagctagtc taaatttttt aaaacaatgg tcaaagatag tcaatatcag
    17221 taatcataac taagtaaaca aaaagaggta aagaatatga ataacaactt taataatttt
    17281 aataacatgg atgatttatt taaccaattg atgggtggta tgcgaggata cagttctgaa
    17341 aatcgccgtt acttaattaa tggacgcgaa gtcacacctg aggaatttgc tcactatcgt
    17401 acgactggtc aattaccagg aaatgcagaa actgatgtgc aaatgccaca acaggcatca
    17461 ggtatgaaac aagacggtgt ccttgcaaaa ctaggtcgaa acttgacagc agaagcgcgt
    17521 gagggcaagt tggatcctgt tatcggacga aacaaggaaa ttcaagaaac atctgaaatc
    17581 ctctcacgcc gcaccaagaa caatcctgtt ttggtcggag atgcaggtgt tggtaagaca
    17641 gcagttgtcg aaggtctagc gcaagccatt gtgaacggag atgttcctgc tgctatcaag
    17701 aacaaggaaa ttatttctat tgatatctca ggtcttgagg ctggtactca ataccgtggt
    17761 agctttgaag aaaatgtcca aaacttagtc aatgaagtga aagaagcagg gaatattatc
    17821 ctcttctttg atgaaattca ccaaattctt ggtgctggta gcactggtgg agacagtggt
    17881 tctaaagggc ttgcggatat tctcaagcca gctctctctc gtggagaatt gacagtgatt
    17941 ggggcaacaa ctcaagacga ataccgtaac accatcttga agaatgctgc tcttgctcgt
    18001 cgtttcaacg aagtgaaggt caatgctcct tcagcagaga atacttttaa aattcttcaa
    18061 ggcattcgtg acctctatca acaacaccac aatgtcatct tgccagacga agtcttgaaa
    18121 gcagcggtgg attattctgt tcaatacatt cctcaacgta gcttgccaga taaggctatt
    18181 gaccttgtcg atgtaacggc tgctcacttg gcggctcaac atccagtaac agatgtgcat
    18241 gctgttgaac gagaaatcga aacggaaaaa gacaagcaag aaaaagcagt tgaagcagaa
    18301 gattttgaag cagctctaaa ctataaaaca cgcattgcag aattggaaaa gaaaatcgaa
    18361 aaccacacag aagatatgaa agtgactgca agtgtcaacg atgtggctga atctgtggaa
    18421 cgaatgacag gtatcccagt atcgcaaatg ggagcttcag atatcgaacg tttgaaagat
    18481 atggctcatc gcttgcaaga caaggtgatt ggtcaagata aggccgtaga agctgtagct
    18541 cgtgctatcc gtcgtaaccg tgctggtttt gatgaaggaa atcgcccaat cggcagcttc
    18601 ctctttgtag ggtctactgg ggttggtaag acggagcttg ctaagcaatt ggcactcgat
    18661 atgtttggaa cccaggatgc gattatccgt ttggatatgt ctgaatacag tgaccgcaca
    18721 gctgtttcta agctaattgg tacaacagca ggctatgtgg gttatgatga caatagcaat
    18781 accttaacag aacgtgttcg tcgcaatcca tactctatca ttctcttgga tgaaattgaa
    18841 aaggctgatc ctcaagttat tacccttctc ctccaagttc tagatgatgg tcgtttgaca
    18901 gatggtcaag gaaatacagt aaacttcaag aacactgtca ttattgcgac ctcaaatgct
    18961 ggatttggct atgaagccaa cttgacagaa gatgcggata aaccagaatt gatggaccgt
    19021 ttgaaaccct tcttccgtcc agaattcctc aaccgcttta atgcagtcat cgagttttca
    19081 cacttgacta aggaagacct ttctaagatt gtagatttga tgttggctga agttaaccaa
    19141 accttggcta agaaagacat tgacttggta gtcagtcaag cggctaaaga ttatatcaca
    19201 gaagaaggtt acgacgaagt catgggggtt cgtcctctcc gtcgcgtggt tgaacaagaa
    19261 attcgtgata aggtgacaga cttccacttg gatcatttag atgctaaaca tctggaagca
    19321 gatatggaag atggcgtttt ggttattcgt gagaaagcct aagacagaat tttgagaata
    19381 aaaaagaagg agccagctga aaaaaactgg ttccttttga ggtacgacgg gcatgtcgtg
    19441 tagtagagat gtactattct agtttcaatc tactatagta gctcagaaat cggtacttaa
    19501 acgtgctata tcaaaaccag tccttgaaaa acgtggactg gtttcgtgtt tggattatta
    19561 ctttgaacga catgcgttaa aagttagttg aaccgccgta tgccgaacgg tacgtacggt
    19621 ggtgtgagag gggctagaga ttatccccta ctcgatttta aatcacatga cgttcaaagg
    19681 catcatctga aatcccttgt tccaagatga gttttgccca ttctttagca gagaagaggc
    19741 tgtggtcctt gtagtttccg caagattcga tggttgtccc tgggacatct tcccaagtag
    19801 tagtttcagc gatttccttg agcgaatcct tgataacagc tgcgatttta gcactggtgt
    19861 gacgtcccca cataatcatg tggaagcctg tgcggcaacc aaatggcgaa cagtcaatca
    19921 tgccgtcaat gcgggtacgg atgagtttgg ctaagaggtg ctcgatagtg tgaaggccgg
    19981 cggtagggat agagtcttcg tttggttgca ccaagcgaat atcataattg gagatgatgt
    20041 ctccttttgg tcctgtttct tccccaatca agcgaacata gggtgctttg acaatggtgt
    20101 ggtcaagttc aaaactttcg acaataactt cttttgacat ggtaaatcct ttcagttttc
    20161 ttctctcatt atatcataaa ggttgctcct gagacagaga gaaaacctct ccgaggctgg
    20221 agaggttgaa atctttactt acgatataag cggtcgtatt ggtagtatgg gtcaaaggtt
    20281 acgttgatac ccagtttacg aaggacattc ttgtcttcat cagtcaagat gatggttgag
    20341 tgggcttcgc ttcctttgag gttgccgagt tcttccatag cgcgggtagc atcaggattt
    20401 tctgtagctg tgatagcaag tgcaatcagg atttcatttg aatgaaggcg tggattgcgg
    20461 ctaccgagat gatcgatttt aagaccttgg attggcttaa caacttccgg ctcgattaat
    20521 tttacttctt tagcgatgtc agctgatttt ttgatggcgt tgatcaaggc agcggctgta
    20581 gggccaaaga gttctgagtt cttaccagtg acgatttccc catttggcaa ttcaaaggct
    20641 agggctggtc caccagtttc ttctgctttt tggcgcgcaa cgacagcaac cttacggtct
    20701 gcaggtgtga taccgaggtc gttcatgagc aactcaattt tcttgacggc agcttcgcca
    20761 actttttcag ctttgaagtc aagaactgtt tgatagtaac ggcggatgat ttcttgttta
    20821 gaagcttcga cagcggcctc gtcatctgta atagcgaaac caaccatgtt gacacccata
    20881 tctgtcggtg aagcgtatgg tgattttccg agaatacgtt ccaacatgcg tttgagcact
    20941 gggaagattt cgatatcacg gttgtagttg acagtggttt ctccataggt ttggagatgg
    21001 aaggggtcaa tcatgttgac atcatcaagg tcagctgtgg cagcttcata agccaagtta
    21061 actggatgat gaaggggaag attccaaaca gggaaggttt caaatttagc gtagccagat
    21121 ttgatgccat tgatttggtc gtggtacata ttggacatac acgttgccaa ttttccagaa
    21181 ccaggtccag gagcggttac gacaatcaag ttgcgactgg ttttgatgta gtcgtttttg
    21241 cccatgcctt ctggggaaat gatgtgatcc atatccgtcg gatatccttt gattggataa
    21301 tgaagatatg aatcaattcc gtttttctca agttggttgc ggaaggcatc tgcagcgggt
    21361 tggccagcgt attgtgtaat gacaacggaa ccaacaaaaa tccccaattc attgaatttg
    21421 tcaatcaaac gaagaacttc ttggtcataa gaaatgccta agtcgccacg tgctttggaa
    21481 tgttcaatgt tgctagcatt aatggcaatc acaacctcaa cctgctcttt caattcttgc
    21541 aagagcttga ttttgttgtc aggttcataa ccaggaagga cacgagcagc gtggaaatct
    21601 tctaacattt taccgccaaa ctctaagtag agcttgccgt caaattggtt aatacgctcc
    21661 aaaatatggt cgcgttgtaa attcaaatat tgttcagaac taaaagcttg ttttttcatt
    21721 tttttacctc tggactctat tataataaaa aattggaagt taggaaacta cggagctaaa
    21781 aaagaaatta aaaagattaa gcaaacgctt gcacaaaatt ttaaaaagtg ctatcataga
    21841 ctatagatta ttaaaataat gaggtaaaca gatgcaagaa aaatggtggc ataatgccgt
    21901 agtctatcaa gtctatccaa agagttttat ggatagtaat ggagatggag ttggtgattt
    21961 gccaggtatt accagtaagt tggactatct agccaagcta ggaatcacag caatttggct
    22021 ttctcccgtt tatgacagcc ctatggatga taatggttac gatattgctg attatcaagc
    22081 gattgcaacg atttttggaa ccatggagga tatggatcaa ctgattgcag aagctaagaa
    22141 gcgtgatatc cgtatcatca tggacttggt ggtcaatcat acctcggatg agcatgcctg
    22201 gtttgtagag gcctgtgaaa atcctaatag ccctgagcga gactactata tctggcgcga
    22261 tgaacccaat gacctagatt ctatctttag tgggtctgct tgggaatacg atgaaaagtc
    22321 aggtcaatac tatctccact ttttcagcaa gaaacagccg gatctcaact gggaaaatga
    22381 aaaacttcgc cagaaaattt atgagatgat gaacttctgg attgataaag gtattggtgg
    22441 tttccgtatg gatgttattg acatgattgg caaaattcct gacgagaagg tagtcaataa
    22501 tggtcctatg ctccatccct atctcaagga aatgaatcag gcgacctttg gagataagga
    22561 tctcttgaca gtaggggaga cttggggagc aacgccagag attgccaagc tctactctga
    22621 tccaaagggg caagaattgt ctatggtctt ccagtttgaa catatcggtc ttcagtatca
    22681 ggaaggtcag cctaaatggc actatcaaaa agagctgaat atcgctaagt taaaagaaat
    22741 cttcaacaaa tggcagacag agttaggagt tgaggacggc tggaattccc tcttctggaa
    22801 caaccatgac ctccctcgta ttgtctcaat atggggaaat gaccaagaat accgcgaaaa
    22861 atctgccaaa gcctttgcaa tcttgcttca tcttatgaga ggaactcctt atatctacca
    22921 aggtgaggag attgggatga ccaactatcc gtttgaaaca ctagatcaag tagaagatat
    22981 tgaatctctc aactatgcgc gtgaggctct tgaaaaaggt gttccgattg aagaaatcat
    23041 ggacagtatc cgtgttattg gacgtgacaa tgcccgtacc cctatgcaat gggacgagag
    23101 caaaaacgct ggtttctcaa caggtcaacc ttggttggcg gttaatccaa attacgagat
    23161 gatcaacgtc caagaagcgc tggcaaatcc agattctatt ttctatacct atcagaaact
    23221 ggtccaaatt cgcaaggaga atagctggct agttcgagct gactttgaat tgcttgatac
    23281 ggctgataag gtctttgctt atatacgtaa ggatggcgac cgtcgcttcc tagttgtggc
    23341 taacttgtcc aatgaagagc aagacttgac agtagaagga aaagtcaaat ctgtcttgat
    23401 tgaaaacacc ctagctcaag aagtctttga aaaacaaatc ttagttccat gggatgcttt
    23461 ctgtgtggaa atgactgact agaatgagca aacctcaagt ttttgaagct tgaggttttt
    23521 tactatagtg gattgaaact agaatagtgc acctctgctt ctaaaacatt gttagaaatc
    23581 gatttgactg tcccgatcga tttgtcctat tcttatttca ttttgctata cttgtagttg
    23641 aggagaatta agctcctcac tagtaaactc ttcataatcc tttttatttt tatgaagata
    23701 ttgtttgaaa gatgtgagtt tccacggatg ggtttgtgga gggatatact tgcgtctttc
    23761 tttttttgtt ctggttcttg ttcaaagttt ttcgaataga gttcatgatt tagtagctcc
    23821 tttgtgtgat agattttgtc agcgatattg aggtagatgt ctccgtcaaa tgcttttata
    23881 actaatgctt tcgtctttct gatgaaatag acttcttttc cttgttcggt agggatatag
    23941 taacgatttt ggaatcggat atggtgtcca ctatcgacga ctctctccgc cagtctagcc
    24001 agaatgagat tcctttcaga ggggttagga acctcctcga agacagagag ttttgtcttg
    24061 tttccaaact gttcattaaa ggtttgaatg taggaaagca ggaaggtatt ggcttcttcc
    24121 aaggtatgaa tattgttttg ttccagttcg ataggcaggc gagattgtag tgtctgattg
    24181 agtctttcga ctctcccttt agcttgaggg atagaggttg tctcaaggag aatccctagt
    24241 tggtgacagg cgtatccaaa ctgtgtatgg gtatcgtcct ccattttctt agagttggag
    24301 gcttgatagg taaagaccgt tctcttatct gttttaattt gaaggggaat gccgtgattg
    24361 gctaagattt gttcgaggac atgatagtaa gcattcaagt tctcttgttt atcaaaataa
    24421 gcgcctagga tattgccaga agcatcatca atggctaagt gtaagttaga tgtttgggct
    24481 ccaaactagg catgagggct ggcatccatt tgaatgagtt caccagcaaa tttctttctg
    24541 ggtctactag gatgtacttt tttagggtct tcaaggaagt tttcagccgt cggtaagatt
    24601 ggattgtcta ggggttgatt caggttcagt ttagcttgtt ttcttactct cttctttgtc
    24661 tttctatggg acttaggcga caggatattt ttcttataga gtatttttct aacagtagta
    24721 tcagagagct gaattccttc ttcttcagct agcaattcac agaaatgaag gacatttggt
    24781 ttatatgttt cataggagag gtattttttt aggagacgtt ctttgatttc atcagggatt
    24841 gcatgttttg gttttcgatt tctgtttccg tgtctgaagg cttcttttcc tttcagttga
    24901 taggctagta gcagacgatt gatttgtctt tcagaaagat tgagctcgac acaggctcgt
    24961 ttctttgttt tctttccttg ggctatagct tttatcacaa gatatttttt cgtttcattc
    25021 atattcagtt ggatcctttt catatgacta ttctaccaaa tgggacattt tcacgttcga
    25081 tttactaaag acattatcac attcgaatta cacaagatgc agatagtgaa aataaaggtg
    25141 tagacattac cgtaaaaaag tgatataatt gtatgatgtt caatgtatag gtgttaatca
    25201 tgagtagacg ttttaaaaaa tcaggttcac agaaagtgaa gcgaagtgtt aatatcgttt
    25261 tgctgactat ttatttattg ttagtttgtt ttttattgtt cttaatcttt aagtacaata
    25321 tccttgcttt tagatatctt aatctagtgg taactgcgtt agtcctacta gttgccttag
    25381 tagggctact cttgattatc tataaaaaag ctgaaaagtt tactattttt ctgttggtgt
    25441 tctctatcct tgtcagctct gtgtcgcttt ttgcagtaca gcagtttgtt ggactgacca
    25501 atcgtttaaa tgcgacttcg aattactcag aatattcaat cagtgtcgct gttttagcag
    25561 atagtgagat cgaaaatgtt acgcaactga cgagtgtgac agcaccgact gggactgata
    25621 atgaaaatat tcaaaaacta ctagctgata tcaagtcaag tcagaatacc gatttgacgg
    25681 tcaaccagag ttcgtcttac ttggcagctt acaagagttt gattgcaggg gagactaagg
    25741 ccattgtcct aaatagtgtc tttgaaaata tcatcgagtc agagtatcca gactacgcat
    25801 cgaagataaa aaagatttat accaagggat tcactaaaaa agtagaagct cctaagacgt
    25861 ctaagaatca gtctttcaat atctatgtta gtggaattga cacctatggt cctattagtt
    25921 cggtgtcgcg atcagatgtc aatatcctga tgactgtcaa tcgagatacc aagaaaatcc
    25981 tcttgaccac aacgccacgt gatgcctatg taccaatcgc agatggtgga aataatcaaa
    26041 aagataaatt aacccatgcg ggcatttatg gagttgattc gtccattcat accctagaga
    26101 acctttatgg tgtagatatt aattattatg ttcgtttgaa ttttacctca tttttgaaat
    26161 tgattgactt attgggaggg gtagatgttc ataatgatca agagttttca gctctacata
    26221 ggaagttcct tttcccagta gggaatgtcc atctagactc tgagcaggct ctaggttttg
    26281 tacgtgaacg ctactcacta gccgatggag accgtgaccg tggtcgcaac caacaaaagg
    26341 tgattgtggc tattcttcaa aaattaacgt caaccgaagc actgaaaaat tatagtacga
    26401 tcattaatag cttgcaagat tctatccaaa caaatatgcc acttgagact atgataaatt
    26461 tggtcaatgc tcagttagaa agtggtggaa cttacaaagt gaattctcaa gatttaaaag
    26521 ggacagatcg gatggatctt ccttcttatg caatgcctga cagtaacctc tatgtgatgg
    26581 aaatagatga tagtagttta gctgtagtta aagcagctat acaggatgtg atggagggta
    26641 gatgaaatga tagacatcca ttcgcatatc gtttttgatg tagatgacgg tcccaagtca
    26701 atagaggaaa gcaaggcact tttaagagaa gcttataatc aaggagttcg aatgattgtg
    26761 tctacttcgc atcgtcgaaa agggatgttt gaaactccgg aagagaagat agcagaaaac
    26821 tttcttcagg ttcgggaaat tgcaaaagaa gtagcagatg atttagtcat agcttatggc
    26881 gcagagatat actatactct ggatgctcta gaaaagctag aaaaaaaaga aattcctacc
    26941 cttaatgata gtcgttatgc tttgattgag tttagcatgc atacttccta tcgtgagatt
    27001 catgcgggat tgagcaatat tttgatgttg ggaatcacgc cagtaattgc tcatattgaa
    27061 cgttatgatg ccttagagaa taacgaaaaa cgtgttcgtg aactgattga tatggggtgc
    27121 tatactcaga taaatagtta tcatgtttta aaacctaagt tctttggtga aaaatataaa
    27181 ttcatgaaaa agagagctcg gtattttttg gaacgtgatt tagttcatgt agttgcaagt
    27241 gacatgcaca atttagacag tagacctcca tatatgcaac aggcatatga tatcattgct
    27301 aagaaatatg gagcgaaaaa agcgaaagaa ttttttgtag ataatcccag aaaaattata
    27361 atggatcaat taatttagga gaaaatatga aggaacaaaa cactttggaa atcgatgtat
    27421 tgcaactatt cagggcttta tggaaaagaa agttggtcat tttattagtg gcaattataa
    27481 cttcttcagt tgcttttgcc tacagtactt ttgttatcaa acctgagttt actagtacga
    27541 ctcggattta tgtagttaac cgtaatcagg aagagaagtc tggtttaacc aatcaagact
    27601 tgcaggcagg atcatacttg gttaaagact atcgtgaaat tatcctatcg caggatgttt
    27661 tggaggaagt tatttctgat ttgaaactag atttgacgcc aaaaggtttg gctaataaaa
    27721 ttaaagtaac agtaccagtt gatacccgta ttgtctctgt ctcagttaat gatcgagttc
    27781 ctgaagaggc aagccgtatc gctaactctt tgagagaagt agctgctcaa aaaattatca
    27841 gtattactcg tgtttctgat gtgacaacac tggaggaggc aagaccggcg atatcaccat
    27901 cttcgccaaa tattaaacgc aatacactaa ttggtttttt ggcagggggg attggaacta
    27961 gtgttatagt tcttcttctt gaacttttgg acactcatgt gaaacgtccg gaagatatcg
    28021 aagatacact gcagatgaca cttttgggag ttgtaccaaa cttgagtaag ttgaaatagg
    28081 agagaggaat gccgacatta gaaatagcac aaaaaaaact ggagttcatt aagaaggcag
    28141 aagaatatta caatgccttg tgtacaaata tacagttgag cggagataaa ctaaaagtaa
    28201 tttccgttac ttctgttaac cctggggaag gaaaaacaac tacttccgta aatatagcaa
    28261 ggtcgtttgc gcgtacaggc tataaaactc ttttgatcga tggcgatact cgaaattcag
    28321 ttatatcagg agtttttaaa tcgcgtgaaa aaattacagg gctaacagaa tttttatctg
    28381 ggacagctga tttatctcac ggtttatgtg atacaaatat tgaaaattta tttgtaattc
    28441 aatcgggatc tgtatcacca aaccctacag ccttgttaca aagtaaaaat tttaatgata
    28501 tgattgaaac attgcgtaaa tattttgatt atatcattgt tgatacagca cctattggaa
    28561 ttgttattga tgcggcaatt atcactcaaa agtgtgatgc gtccatcttg gtaacagcaa
    28621 taggtgaggt gaataaacgt gatgtccaaa aagcgaaaca acaattagaa caaacagaga
    28681 aactgttcct aggagttgtt ttaaataaat tggatatctc ggttgataag tatggagttt
    28741 acggttccta tggaaattat ggtaaaaaat aacttaggaa agattttatg gatgaaaaag
    28801 gattgaaaat ttttctagca gtaatacaga gtattattgt cattttattg gtttattttc
    28861 ttagctttgt tagagagaca gaacttgaac gttcttcgat ggttatacta taccttctcc
    28921 acttttttgt attctatttt agttcctatg gtaacaattt ttttaaaaga gggtacctag
    28981 ttgagtttaa tagtactata agatatattt ttttctttgc aatagctata agtgtattaa
    29041 acttttttat agcggaacgg tttagtatct ctagaagagg aatggtatac ttcttaactt
    29101 tagaaggaat atccttatac ttgttaaatt tcttagtaaa gaaatattgg aagcatgtgt
    29161 tttttaatct aaaaaatagc aagaaaattt tactgttaac agtaacgaaa aatatggaaa
    29221 aagttcttga taaattgcta gaatctgatg aactttcatg gaaattggta gcagtaagtg
    29281 ttttggataa atctgatttt caacatgata aaatacctgt aattgaaaag gaaaaaatta
    29341 ttgaatttgc aacgcatgaa gttgtggatg aggtgtttgt caatcttcca ggagagagct
    29401 acgatattgg agaaattatc tctaggtttg agacaatggg gatagatgta actgtaaatc
    29461 ttaaagcatt tgataagaat ttgggtcgca ataaacaaat tcatgagatg gtaggattga
    29521 atgtagtcac tttctctaca aatttttata aaactagtca tgtgatttca aagagaattc
    29581 tcgatatttg tggtgccact attggcctta ttctttttgc tatagctagt ctagttttag
    29641 ttccattgat tcgtaaagat ggcggatcag ctatttttgc tcaaactcgt atagggaaaa
    29701 atggtcgaca ttttaccttt tataaattcc gttcgatgcg aatcgatgct gaagctatca
    29761 aagaacagtt gatggatcaa aatacgatgc aaggtggtat gtttaagata gacaatgatc
    29821 ctcgtgttac aaaaattggt cgctttattc gtaaaactag tttagatgaa ttgccgcagt
    29881 tttggaatgt ctttatagga gatatgagtt tggtgggaac acgtccacct acagtagacg
    29941 agtatgatca gtatactcca gaacagaaac gtcgactcag ctttaaacct ggtattacag
    30001 gtttatggca ggttagcggc cgtagtaaaa taaccgattt tgacgatgtt gtaaaattag
    30061 atgtggctta tattgataat tggacaatct ggaaagatat tgaaattttg cttaaaactg
    30121 ttaaagttgt atttatgaga gatggagcga agtaattcat atgaatgaga gaatgcaaat
    30181 attaggagtt actatagatc cattaacgat gaaagaaaca gtggatgctg ttgaacagta
    30241 tgttttaaag aagcatcctt tgcacttgat gggagttaac gcagataaaa ttaatcagtg
    30301 ccatgaagat gagaaaatca aaaaaatcgt taatgaatca ggaatcatta atgcggatgg
    30361 agcatcagtt gttcttgcaa gtaagttttt aggaacgcct gttcctgaac gagtagcggg
    30421 tattgatttg atgcaatgtc ttttagagtt gtcaaataaa aaaggatatt cagtttactt
    30481 ttttggagct aaagaagaaa ttttacaaga tatgctaaaa gtttttaaac aaagatatcc
    30541 taatcttaat gttgttggct atagaaacgg atatttttca cctgaagatg aaaaaaagat
    30601 tcaggaagat attaaaggag gaaaaccaga ttttgtattt gtagggatta cttctcctaa
    30661 aaaggagtat atcatccaat cattcatgga taatgggatt aatgctgtct ttatgggtgt
    30721 tggtggcagt tttgatgtat tatcaggaca cattaaacga gctccattat ggatgcaaaa
    30781 attgaatctg gaatggttgt tccgtgtagt taatgaaccc aaacgccttt ttaagcgtta
    30841 ttttataggg aatgttactt ttattaagcg agttttagat gaaaagcgaa aatcaaaaaa
    30901 ataatattct acatatttct cgtacaatgg atattggtgg tgcagaacgt attgtatatc
    30961 aattgagttc tgatttgaaa gatgaatttg atagtgtcca tgtcgcttca acaggtggac
    31021 tatgggagag caaactttta tcaaaaggag ttcaacatca taaaatttta gatgttgaca
    31081 gtaagaatcc cctaactatg gtaaagatcc tttcaagttt ttatagaatt atcaaaaata
    31141 atgatattac cattgttcac actcatcatc ggatggctgc cttttatatt cgcttgttga
    31201 aaatcattaa tcctaagttg atacatgttt acactgcaca taatgtattt aaaaataaat
    31261 taccattata caaattttcc ttaaaaaaag cgtattgtgt agctgtaagt aaagcggtta
    31321 atgataattt gaaacatgat gtaggaatca gtgatagtac agtaatctat aatggggttg
    31381 tttttgaaaa aactgataag ctagttggtg aaattgtaaa ctataacgga atcaaattgg
    31441 ggtgtattgc taggttatca gagcaaaaag gattgaccta cctaattgat gcgatgtctt
    31501 tagtgaaaca caggaatatt acgttgttca ttgtcggaga tggagagctt cgagatgagc
    31561 ttgaaaacaa ggtgaaacaa ttaaatcttc aaaaatcagt gatattttta ggttatcgaa
    31621 aagatattgt tgaatgtatc aatagttttg attacttagt gtcatcatct ttatatgagg
    31681 ggtttggtct aaatgcaatt gaagcattta tgaaggggaa aacgatggtt tcatcagata
    31741 tcccaggaat aaatgaagta gtcaataaca aaaatgggat tcttgttcct gttaaggatg
    31801 atgttgcctt agcgagagcg attgaaaagc ttgcgactga caaaaaactt agagaaaaac
    31861 tcgcttatca agcaaaaaaa gattatgaga caaaatttaa ttattccttg tttttggata
    31921 attatcggag actttataga aaattaatgg gagaatcaaa atgaaaaaag tcatgttggt
    31981 ttttgggaca cgtccagaag ctattaaaat gtgtccttta gtaaatgaac tgaaacaaaa
    32041 tgattcaatc aagacacttg tgtgtgtaac tggtcaacat aaggaaatgt tagagcaggt
    32101 tttagaggtg ttcaaggttg tcccagatta tgatttgggt atcatgaaag caaatcagac
    32161 cctatttacc attacgacta gtatcttgga taaaattcag gcggttctag agaaagaaaa
    32221 accagatctt gttcttgttc atggagatac tacaacaaca tttgcgacag ctttagcagc
    32281 attttatatg ggaatcaaag tgggacacgt cgaagcaggt ctcagaacct ataatctcca
    32341 aagtccattt ccagaggaat tcaatcgcca gacaacttct atcattgccg actatcattt
    32401 tgcgccgact gaagttgcga aggaaaatct actaagagag gacagaaaaa atatctttgt
    32461 gacgggaaat acagtcattg atgctttgaa gacgactgtt caagataact accatcaccc
    32521 aattttagaa tgggcaaagg gtagtaagtt aatcatgcta acggctcatc gacgagaaaa
    32581 tcttgggaaa ccgatggaaa acatgtttaa tgctgttaat cgaattttaa acgaattcga
    32641 agatgtaaaa gttgtatatc ccatccataa aaatcctaag gttcgagaat tagcaagtaa
    32701 agtttttggc gataatgaac gaatgaaaat cattgaaccg ttagaggtta ttgattttca
    32761 taattttatg aatcaaagct atatgatttt gacagattct ggaggtgtac aggaagaagc
    32821 accttcttta ggaaaacctg tcttggtgat gcgtgataca acagagcgtc ctgagggggt
    32881 cgttgctggc acgttgaagt tggtaggaac agaagaagag aatatctata gcaacttcaa
    32941 acttcttctt gaagatgaaa cagaatataa caagatgagc aaagctagca acccttatgg
    33001 agatggaatg acttgtaaac ggattgttga tattattctg gaagtataaa aataattcaa
    33061 ttatggatga ggaaagaata aattagattg atgataaaaa gaaaaatata tataatctgt
    33121 gtattactgt cgtatttttt acctagtttt tttacagttg gatcaatggc gactttattt
    33181 gctttgcttt ctactttagt taagctattt gtaacttttg attatattcc caaagttctt
    33241 ttacagcata aagtaacact gattgatatt ctagttgttc tatttttatt ttttcaagca
    33301 tttgcagctt ttcaaagcca aacgttgtac cttaactatg ttggaggtca gtttttcctt
    33361 ttaggactat attcattttt gaaacacttt ttattgttgg attgtaaaac aacaataaaa
    33421 agcctctttt taacctttat cttgtttttg tgtgttcaag taataactca attgcttttt
    33481 ccggtcggtt tcgattcttt gcaccctaca ggagataata gactttactt tttaggaaga
    33541 aagaacatag ctaccccgta tatcattgtt ggattaggtg gtttttactt attaaataaa
    33601 aaaatgaatg agtttatatc actaaaggag attatttttt taggattgtt cggaatttta
    33661 tcatttttaa cacaatccag tacagcgatt atatgttatg ggctttttat tttcatacgt
    33721 ctattgggat taaaggaaaa tataggaaaa ctatattctt tagtcagtat ggctgtatat
    33781 gtttgttttt ctctttctat aatcttttca caaagtacaa ttttatcaac ttttacagcg
    33841 attttttcca aaaatgcaac tttttcagga cgtatcaata tttggcaatt agcgattcgt
    33901 atttttgaag agaatttttg gtttggacga ggcctcaacg ttaattttaa tgcttggaca
    33961 aatgggatta tcgttaattc agcacacaat accttattag atatacttgc tcgaactggt
    34021 atatttccag gtgttttatt tatagtgctt cttatgaatc tgtttcttgg aaaatataga
    34081 atagaatcaa aaacactgtt ggctatgtta gcctcattta tgatttatat tacaatggag
    34141 acttcatcta tgagcatatt gctgctaatt attgttcttt gtgtatattg gccacgtgga
    34201 gaggagaagt tgcatgagca agttacttaa taccatctat tatcgactat ttagattata
    34261 taaaaaaatt tatctacaag tttttagtaa aaaaacggtt gacatcttgg gtgaaaaggc
    34321 taatttagaa aatgaactaa ttgtttcgtt tacaacaatt ccaagtcgtc ttaattattt
    34381 accaagtatg attaaaagta ttttcaatca gacaattatc cctaaccgtt ttattatgta
    34441 tgtttataaa gatgaatttg aaggcattaa tttggagagt attctagaac ttgaaatcaa
    34501 aaatggtttg gaaattgtct atgtggatga gaatcttcgt tcacacaaaa aatattttta
    34561 tgctatgaag gataatccga acagtatagt tgttctagtt gatgacgata tcatttatcc
    34621 tcgaaatact ataaagaaac tgattgcatc ctatagaatt tatccacagt gtgtttcagc
    34681 aatgcgatgt catcgaatta agttgttttc tgatggaagt ttatatccat ataatcaatg
    34741 ggaatatgaa atatcaggag ctactatacc atcgtatttt aattttttta ctagcggagg
    34801 tgggacatta tttcctccat gtactcgcaa tgaggatctt tttaataaaa aaaatatcag
    34861 ggaactcagt tttctagctg atgatgtatg gttgaatttt ttggtagtca aaaatggaat
    34921 taaaacagta aaagcaacac gatataaagg gacaccatta actatagatg acaatcctga
    34981 ggagagtttg gtatatttga ataccgtata tgataacaac aatgataaat gtattagaaa
    35041 tatggttgaa tattatcaaa ttaattttac agaggataaa taatgaatgt tgaaaaaaat
    35101 ttgaaacgtg gaattttcta tactgcaata gggaagtatt cgaatgtagt tattcaatta
    35161 cttgtaacag caattcttag ccggattctc tcacctgtag aatatggtat cgtagcagta
    35221 gtaaatgtat ttcttttatt ttttcaaatg ttagcagatt caggaatagg acctgctatt
    35281 gttcaaaata aagaactgaa taagtcagat ttaatcagca ttttctcatt aacgatttat
    35341 agtggaatcg tactttcttg tatttttgct ttactaggat atcctatggg ggtgttatac
    35401 ggcgaaacta tttatgttag tttatttccg cttttaggtc tttgtgtttt attttatacc
    35461 attacaattg taccgcaagc tattctaatg aaaacgatga actttaaaat agttaatttt
    35521 ctaactattt tttctaacat tgctagtggc ttggtgggcg ttattctagc ggtatcacat
    35581 tttggtgtct attctctaat tttttctaat attgtaaaag caatggtttt atttatcgct
    35641 ttatattcta aagcaaagat aaatttctat tggaaagttt caaaaagttc tattggtaaa
    35701 atttttgagt tttcaaaatt ccaatttttg tttaattttt ggaattattt tgctagaaat
    35761 ttagataatt tattaattgg acgattgatt agcccgtcag atcttggtta ttatgataag
    35821 gcttatcaat tatctttgta ccctaatcaa attttatcac aggttgtgac accagcattg
    35881 catcctatta tgtccaattt tcaagataat atcagtaaga taggcgaagt ttatcttcag
    35941 atttctagaa tattcgtaat agttggcata cctatttcgg cttatttata ctttaatgct
    36001 caatatgttg ttacatttat gtttggagat aattggtccc aaagcgttcc ggtgtttcaa
    36061 atattagcag caacaatttg gttacaaatg gctaatagcc ctactggtgc attttaccaa
    36121 gcaactaatc agacaaagtt attgtttaga attggcttat tgacatcttt tattaatatt
    36181 ttagctattg ttattggtgt aatgttgcaa agcatccaat gtgttgcgta catgcttttg
    36241 atttctttca gtcttagttt agtaatcaat actctttact taacaaaaaa agtattaaat
    36301 atttctgctc aaaaatatat aaaaccgata ttaattaatt tgacaattat cagtccctat
    36361 attgtgttta atttgtttat ctcggatttt gtaaacgacc ttattttaca tttatcagtt
    36421 cagtttgtta ttttattttt aatatgggga attgggatgt atattagcgg agagtatcga
    36481 cgagtcttcg cggttataag aaaataaagg agcaattttg tgaaaatttt atttgtgaat
    36541 atgttttata atgaagcagg aggtgcacaa aagagcacca aatttctagc tgaacaactt
    36601 gtaaaagaag gacatgaggt atttgcatac tctgatgatg ccattgattc agatattgat
    36661 gaagttatta atagggttaa gatttttaga agaagaaccc cgctttttag tcttcactat
    36721 attttcagtg ctaagaagaa tccagctaaa cattttttct ataaaatatt tgaaacctat
    36781 aatgtatttg cgaaaagaaa atttatcaat atcattgagg aagtacaacc agatattgtt
    36841 cactttaata caatttcagg aatgtcttta tcaatagtta aagaagctaa aaagagaaat
    36901 atcaggaccg tttggacctt gcgagactat tggctagaat atccatgggg tgagaaagat
    36961 atttctctta tcaaacttct aaatagaata tatagacctt ttgttaagaa aagtttaaga
    37021 cacttagaca tagtaacagc accatcagca tttactttga ataattttat caataaagga
    37081 tttattaacc catcttctca aaaatgtatg gtcattgaaa atgctgttat attttcaaag
    37141 ggtaagttgg aaaatattat caaacaaaag caagaaacaa aaagaaatcc agaaaaaacg
    37201 aattttcttt ttgtaggttc tatacttgaa ataaagggcg tttttaactt agtaaaggcc
    37261 tttaaaaaac taactagtcc ggaaatttct ttgaaaattg taggaaaagg aaaagattta
    37321 gaaaaacttc aaaaagaaat tgagagtgat cctagaatac aatatttagg ctttcaagat
    37381 acagaaaccc tctataaaac ttatcaaaat tcggatgtat tggtcgtccc atctgcttgg
    37441 gatgaaccgt ttggtagagt tgtaattgaa ggaaatgcaa atggccttcc tgtcatcact
    37501 tcagatagag gtggattacc tgaaattgtg caaacagtag gaggaggaga aatttttaca
    37561 gatgaatcgg gaaatacatt atatagtctt ttaaagaaat ttgtagaaat ggaaaactac
    37621 aatgtctatt accaatgcat tcttgagaat attgatattt attctatcga aaaacaaagt
    37681 gaaaagttca ctaatctgta tttagataaa gaaatcgaat aataagttgt ttttgtagca
    37741 gtaacggagg taattatgaa aatagcggta gcaggaacag gttatgtagg attatcaatt
    37801 gctgtgttgt tggcacaaca tcacgaaata aaagcagttg atattgttgc tgaaaaagtt
    37861 gaattaatca atcaaaaaaa gtctccaatt caggatgatt atattgaaaa atatttagtg
    37921 gaaaaagatt taaatttgga agcaactatg gatgctaagt atgcttatga agatgcagaa
    37981 tttgttgttg ttgcagcacc aacaaattat gattcgaaaa agaacttttt tgatacatca
    38041 gcagtagagg cggtcattca acaagtaaaa aaaattaatc ccaaagcggt aataattatt
    38101 aaatctacaa tccctgttgg attcacagag tccgttcaaa agaaatatca gtataaaaat
    38161 atcttattta gtccagaatt tttacgcgaa tctaaagcat tatacgataa cctgtatcca
    38221 agtcgcatca ttgttggaac tgacttagaa gatacttatt taaaagacaa agctaatata
    38281 tttgcttccc tactaaaaga gggggctatt aaagaagaca tagatacact tttcatggga
    38341 gtaacggaag ctgaggcagt taaattattt gccaatacct accttgcgtt gcgtgtttct
    38401 tactttaatg aattggatac ttatgcagag gtgaaaggtt tggatgcaaa agccattatt
    38461 gatggtattg gcctagatcc acgtatagga aatcattata acaatccatc ctttggctac
    38521 ggtgggtatt gtttacctaa agatagtaag cagttattag caaattactt tgatgtacca
    38581 caaaatatga tgacagcaac tgttgaaagc aatcgaacgc gtaaggattt tatcgctcaa
    38641 cggattttag aaaaagctgg agtatctgag actgatagtt tagatgcgtt taagaacata
    38701 caagatattg ttataggtat ttatcgttta acaatgaaaa gtaattcgga taacttccgt
    38761 cactcctcta ttcaaggcgt tatgaaacga ttgaaagcta agggagttac ggttatcatc
    38821 tatgagccaa ctttgaagga cggggaaaca ttctttggta ataaagtggt aaataatcta
    38881 gataaattta aagaagctag taatgttatt gtagccaatc gttttgaacc ttcactagag
    38941 gatgtgtcta ataaagttta tagtcgagat atatttaagc gtgactaata aatacgtcca
    39001 cgtgacgtaa tatctattaa atgaataaaa tattaataaa catggcatcg atatcttttt
    39061 tggacttgaa ttgtcaaatt aagtgcacat ttttttcata gaaaacttca taaggtgttt
    39121 tccggttaag acattttcgt ggtctattat ctaagttggt ttatataata gacttcctgc
    39181 gaaacaaaat atggtataat agttctatga attatgaagc aagtaaacaa ctaaccgatg
    39241 tacgatttaa gcgtcttgtt ggtgttcaac gcacgacttt tgaagagatg ttagctgtat
    39301 taaaaacagc ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa ttaagcctag
    39361 aagactttct tatggcgact cttcaataag tgcgagaata ccgcacttat gaaca
//
LOCUS       DBERCW010000019        36073 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.019, whole genome shotgun sequence.
ACCESSION   DBERCW010000019 DBERCW010000000
VERSION     DBERCW010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.019"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(299..481)
                     /locus_tag="ACL72M_001167"
     CDS             complement(299..481)
                     /locus_tag="ACL72M_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716297.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            complement(483..1262)
                     /locus_tag="ACL72M_001168"
     CDS             complement(483..1262)
                     /locus_tag="ACL72M_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716298.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            complement(1541..1891)
                     /gene="rbfA"
                     /locus_tag="ACL72M_001169"
     CDS             complement(1541..1891)
                     /gene="rbfA"
                     /locus_tag="ACL72M_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGS0716299.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(2142..4934)
                     /gene="infB"
                     /locus_tag="ACL72M_001170"
     CDS             complement(2142..4934)
                     /gene="infB"
                     /locus_tag="ACL72M_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGS0716300.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(4951..5250)
                     /locus_tag="ACL72M_001171"
     CDS             complement(4951..5250)
                     /locus_tag="ACL72M_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGS0716301.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(5243..5536)
                     /locus_tag="ACL72M_001172"
     CDS             complement(5243..5536)
                     /locus_tag="ACL72M_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGS0716302.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(5558..6694)
                     /gene="nusA"
                     /locus_tag="ACL72M_001173"
     CDS             complement(5558..6694)
                     /gene="nusA"
                     /locus_tag="ACL72M_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGS0716303.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(6738..7217)
                     /gene="rimP"
                     /locus_tag="ACL72M_001174"
     CDS             complement(6738..7217)
                     /gene="rimP"
                     /locus_tag="ACL72M_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGS0716304.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(7343..7978)
                     /gene="trmB"
                     /locus_tag="ACL72M_001175"
     CDS             complement(7343..7978)
                     /gene="trmB"
                     /locus_tag="ACL72M_001175"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGS0716305.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(7975..8769)
                     /gene="ccrZ"
                     /locus_tag="ACL72M_001176"
     CDS             complement(7975..8769)
                     /gene="ccrZ"
                     /locus_tag="ACL72M_001176"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGS0716306.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(8930..9541)
                     /locus_tag="ACL72M_001177"
     CDS             complement(8930..9541)
                     /locus_tag="ACL72M_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0716307.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            complement(9692..9925)
                     /gene="blpZ"
                     /locus_tag="ACL72M_001178"
     CDS             complement(9692..9925)
                     /gene="blpZ"
                     /locus_tag="ACL72M_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGS0716308.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(9967..10656)
                     /locus_tag="ACL72M_001179"
     CDS             complement(9967..10656)
                     /locus_tag="ACL72M_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0716309.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            complement(10708..11091)
                     /locus_tag="ACL72M_001180"
     CDS             complement(10708..11091)
                     /locus_tag="ACL72M_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGS0716310.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(11720..12039)
                     /locus_tag="ACL72M_001181"
                     /pseudo
     CDS             complement(11720..12039)
                     /locus_tag="ACL72M_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(12559..12678)
                     /locus_tag="ACL72M_001182"
     CDS             complement(12559..12678)
                     /locus_tag="ACL72M_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS0716311.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(12782..12931)
                     /gene="blpO"
                     /locus_tag="ACL72M_001183"
     CDS             complement(12782..12931)
                     /gene="blpO"
                     /locus_tag="ACL72M_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGS0716312.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(13175..13423)
                     /gene="blpK"
                     /locus_tag="ACL72M_001184"
     CDS             complement(13175..13423)
                     /gene="blpK"
                     /locus_tag="ACL72M_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HGS0716313.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(13492..13761)
                     /gene="blpJ"
                     /locus_tag="ACL72M_001185"
     CDS             complement(13492..13761)
                     /gene="blpJ"
                     /locus_tag="ACL72M_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGS0716314.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSL"
     gene            complement(14228..14425)
                     /gene="blpI"
                     /locus_tag="ACL72M_001186"
     CDS             complement(14228..14425)
                     /gene="blpI"
                     /locus_tag="ACL72M_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGS0716315.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            14708..15295
                     /locus_tag="ACL72M_001187"
     CDS             14708..15295
                     /locus_tag="ACL72M_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGS0716316.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            15222..16865
                     /locus_tag="ACL72M_001188"
     CDS             15222..16865
                     /locus_tag="ACL72M_001188"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGS0716317.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            16876..18237
                     /locus_tag="ACL72M_001189"
     CDS             16876..18237
                     /locus_tag="ACL72M_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGS0716318.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            18294..18422
                     /gene="blpC"
                     /locus_tag="ACL72M_001190"
     CDS             18294..18422
                     /gene="blpC"
                     /locus_tag="ACL72M_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGS0716319.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(18493..19833)
                     /locus_tag="ACL72M_001191"
     CDS             complement(18493..19833)
                     /locus_tag="ACL72M_001191"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0716320.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(19847..20584)
                     /locus_tag="ACL72M_001192"
     CDS             complement(19847..20584)
                     /locus_tag="ACL72M_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0716321.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(20589..20927)
                     /locus_tag="ACL72M_001193"
     CDS             complement(20589..20927)
                     /locus_tag="ACL72M_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0716322.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            21203..21532
                     /locus_tag="ACL72M_001194"
     CDS             21203..21532
                     /locus_tag="ACL72M_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS0716323.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(21700..22749)
                     /locus_tag="ACL72M_001195"
     CDS             complement(21700..22749)
                     /locus_tag="ACL72M_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716324.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(22746..23477)
                     /locus_tag="ACL72M_001196"
     CDS             complement(22746..23477)
                     /locus_tag="ACL72M_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716325.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            23545..23955
                     /locus_tag="ACL72M_001197"
     CDS             23545..23955
                     /locus_tag="ACL72M_001197"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS0716326.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            23965..24252
                     /locus_tag="ACL72M_001198"
     CDS             23965..24252
                     /locus_tag="ACL72M_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716327.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            24507..24698
                     /locus_tag="ACL72M_001199"
     CDS             24507..24698
                     /locus_tag="ACL72M_001199"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716328.1"
                     /translation="MDRTDEVSSKHCFEVVDTTDEVSSKHCFEVVDRTDEVSNHTHDK
                     PTLTWFEEIFEEYHSPFHN"
     gene            complement(25010..26146)
                     /gene="dnaJ"
                     /locus_tag="ACL72M_001200"
     CDS             complement(25010..26146)
                     /gene="dnaJ"
                     /locus_tag="ACL72M_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGS0716329.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(26548..26904)
                     /locus_tag="ACL72M_001201"
     CDS             complement(26548..26904)
                     /locus_tag="ACL72M_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGS0716330.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVPAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(26906..28729)
                     /gene="dnaK"
                     /locus_tag="ACL72M_001202"
     CDS             complement(26906..28729)
                     /gene="dnaK"
                     /locus_tag="ACL72M_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGS0716331.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(29209..29733)
                     /gene="grpE"
                     /locus_tag="ACL72M_001203"
     CDS             complement(29209..29733)
                     /gene="grpE"
                     /locus_tag="ACL72M_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGS0716332.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(29760..30794)
                     /gene="hrcA"
                     /locus_tag="ACL72M_001204"
     CDS             complement(29760..30794)
                     /gene="hrcA"
                     /locus_tag="ACL72M_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGS0716333.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(30958..31467)
                     /locus_tag="ACL72M_001205"
     CDS             complement(30958..31467)
                     /locus_tag="ACL72M_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGS0716334.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            32075..34408
                     /gene="hsdR"
                     /locus_tag="ACL72M_001206"
     CDS             32075..34408
                     /gene="hsdR"
                     /locus_tag="ACL72M_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGS0716335.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            34421..35884
                     /locus_tag="ACL72M_001207"
     CDS             34421..35884
                     /locus_tag="ACL72M_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS0716336.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            35884..>36073
                     /locus_tag="ACL72M_001208"
     CDS             35884..>36073
                     /locus_tag="ACL72M_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGS0716337.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT        11261 a         7591 c         6411 g        10810 t
ORIGIN      
        1 aacatatata ctgcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa
       61 tgattttact gcttatatta taccatatgg agagagatta aaaaactagc agtggagttc
      121 ctgctagctc tctgcgactt ggattaccat ctagataagt ttaaagagcc aatccaatat
      181 cttaaacaat atcttgtaaa acagcaattg aactgcaaag gaaatgatca tccaaaagaa
      241 tttcacaatc ccaataatcg gtttgataaa aagaatagca agaagaccaa aaaaaatttc
      301 attctctctc ctctggccta atgagccacc gagccgtatc cattagctta tctgcaataa
      361 aaagttttcc cagaccaaca acgacatggt cagctttctt tatcgttttc atcactttta
      421 caccttgcac ggtcaaaaag taattaccat aaattttatc aaaagctttg ataggattca
      481 tattactctc ctttaatgat ttcagcctct tttcggattg tttcaacatc ttcttgatat
      541 tgaacttcac tatagttgac tagcttggat aattctttct gcaagctttc ccccattggt
      601 ttcatagttg caaaggttaa accacctgca atgataccac ccaagatagg aataaatttc
      661 cctattcctt tggccagccc tcccttggta agattcacac caaatatttt taagactttt
      721 ttcaaaatag ggtaccaaag cgtctttgtt aaagctttat taggcactgt tttcattacc
      781 tgtttggcaa ttgttatacc accagcacat agcaaagcag cggttccatt cacccctaac
      841 attacgccta gataaagcaa gagggtattt tgagcatctt cactcaactc ctcgcgtgaa
      901 gcccaaagat cctcataacc ataaatataa cctaattctt gagccaattt cagagagaaa
      961 gcataaaatt gagccacatc agctggaatg gtaattgcca tagcaagccc tccagctaat
     1021 cctgccaaaa cagaagtccc actcgctaat aatacattgt cccgaataca agcattagct
     1081 acacgatcta atatttcttg agatagaaga gtcgttgtac cttgttccaa taaggtagga
     1141 atatcttttg gatccaattc tttggaaaac ttatccacta aaaatttcga acgatcaacc
     1201 ttaacaacag gtagtttcac cacttgttgc aatacttgca tagctaagtc ttgttcagcc
     1261 atatacaaac tccttatttc ttttttacac cttatcatat tatatttcct acaaaaaaag
     1321 cattttctaa ttagataaca ttaaaaaata cagaacccct tttttatagt aaaatgaaac
     1381 aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag
     1441 aggcgtacta ttctagtttc aatatatttt aaaagaatat ttttccattt caaattcaac
     1501 ctattttcct ccaccaaaaa agaggggcaa cccctcttct ttagttctta tccagattgc
     1561 gtagcatctc gtcaatcttg tttccatact cgatggactc gtctttgacg aaggtcaaat
     1621 ctgggatttt gtacaatttc aaattgcgac caagttcacg tttgatggta ccagttgctt
     1681 tttcaagccc gatttgggct ttttggttat ccgaagcaag gttactcaaa atggtgtaat
     1741 aaaccttggc aacagacaag tcacccagca tctgaacatc tgtgatggtc acaccttgga
     1801 cacgtggatc acggactttc ttttgcaaaa tctcattgac ttcacgcttg atttccatgc
     1861 ccacacgatc tgtacggaaa tgatttgcca tgatattcct ttctctactt tgaaccaaaa
     1921 gctaggccag cagacctagc tattttaaac ttcttgattt tcagtttaaa ttgaaacgaa
     1981 gttcaatttg aagtcatctg cttctttcgc cgtggtgaaa gtgatggaac tgatttatca
     2041 gtcccatcac aggggatttt tgagacccta ggctcaaaaa taagcaatga aaccatcggt
     2101 ttgcttgcgt ccctcaccac ctaagaaagg agcaaaaaat cttatctctt gatttcttcc
     2161 atgacatacg cctcaatcac atcatccatc ttaatatcat tgtagccgtc gatcatcaat
     2221 ccaccttcac gaccgtttgt cacttctttc acgtcgtctt tgtagtgttt caagcttgcg
     2281 agttcgccat catagataac gacaccatca cggataacac ggactttaga gtcacgggca
     2341 accttaccgt tgataaccat aaatccaccg atagttccca ctttagacac cttgaaggtt
     2401 tcacggataa ccgcttcacc aataactttt tcttcaaatt ctggatcaag catccctttc
     2461 atagcttctt ccatctcttc gataaccttg tagataatgc tgtgaagacg gatttccaca
     2521 tcgtcagctt ctgcttgttg acgagcttgt ggtgtagggc gtacgttgaa accaacgata
     2581 aaggcatttg aagcttcggc aagggtcacg tctgattcgt tgatagcacc gaccgctgag
     2641 tggacgatag tcactttgac accttccacg tcaatctttt gaagtgaggc agaaagggct
     2701 tcaacagaac cttgtacatc agccttgatg ataacattaa cagatttgag ttccccagct
     2761 ttaagggtat caaagaggtt ttcaaggcta acacgttggg tagcttgacg ttgtttcatg
     2821 agggcacgtt tggcacgctc ttcacctgct gcacgcgcag atttttcatc ctcgtaaacg
     2881 gcaaagtggt cacccgccat cggtgcttcg ttcaaacctg tgatagagac tggtgttgat
     2941 ggtccagcaa ctttaacacg acgaccaagg tcgttggtca tagcacggac acgaccgaag
     3001 gtatttccga caacgattgg atcttgaaca ttcaaggtac cttgttgtac aagaagggtt
     3061 gcgaccgcac cttttccttt atccaagcgc gcttcgataa ccgtaccgat tgcacgcact
     3121 gttgggtctg ccttgagttc ttggatttca gctacaagaa ggactgtttc caacaattct
     3181 tcgatatttt ggttgaattt agctgagatt tcaacaaatt cagaatctcc accccaagcg
     3241 gttgacatca caccatgctc tgccaattca ccgataacgc gttctgggtt agcacctggt
     3301 ttatcaatct tgttaatagc tacgatgatt ggaacgttag ctgcttttga gtggttgatg
     3361 gcttcaatag tctgaggcat aaccccgtca tctgccgcta cgaccaagat cgtaatatcg
     3421 gtaacagaag caccacgcgc acgcattgat gtaaaggccg cgtgtcctgg tgtatcaagg
     3481 aaggtaatct tcttaccatt ttccacgatt tggtaggcac cgatatgctg agtaatacca
     3541 cctgcttcac ctgtcgcaac acgtgagtta cgaagagtat ccaaaagggt tgttttaccg
     3601 tggtcaacgt gtcccatgat agtaacaact ggtggacgct caaccaattc atcttcattg
     3661 agataaccat cttcgacaaa gaaacgttcg atgtcagcat tatccacttc aaccttttgt
     3721 ttggcttcga taccgtaatc caccatgagg agttcaattg tttccccatc caaggattgg
     3781 ttttgtgtgg ccatgacacc catcatgaaa agtttcttaa caatttcagc tggttcacgt
     3841 ttgatacgtt ttgcgatttc cgcaacggtc ataccatctg tatattcaaa ttctgttggc
     3901 aattcatgga atttacgctc cgtaacaggt tttggagtct gattacggtt gttcttgtta
     3961 ttgccttttt tgttcttttt gttgttattc cagttactat tcttttgatt tctcacttga
     4021 ttttgactac ttcgattctt ttgttgtttt ctaggaccat cttcttcatg atcataatcg
     4081 tcacgatttt tgtctggtcg agcttgtttt ttacgacgtg tatccactgc aggttctttt
     4141 ttctcaggga cgacttcaac cactgcttga acttgctgtg cttgttcagc taacttagcc
     4201 gcttcttcaa agatttcctc tggttccttg cgtttgttag cttgagccaa ggcttcttta
     4261 gcagcctgat actgcttgaa gcgttcctca cttgaacgag cgtactctgc attttgctct
     4321 gcttttaggg ctgctgcacg ggctttaaag tcaatacgtg gagccgcttg atttgaacgt
     4381 ttatcctctt gctgacggcg ctcatttcta cgtttttgct gaccttgctg cttcttagct
     4441 tggtcattaa agcgacgatt gtcgcggttg ctttgacctt gttttccacc attacggccg
     4501 tcgtttttct gacggtttcc gttttgttgt tggtcacggt tattgccctt attttgcttg
     4561 cgtcgttctg cctgctcttt agcacgggct tcacgctcag ccttgaaatt acgactttgc
     4621 ggtttcactg ctactttttc tgttttcgga gcaactggct cagccggttt tgcctcttcc
     4681 ttagctacag ctggtttagc tggctcagat ttttcggctt tcttttctgc acttactttt
     4741 ggtgctgcag gttttgcttc tactttcgga gcagctgcag gcttaaagct ggcagcaatt
     4801 tttgcagcga cagcttcttc cacacttgat gagtggcttt tcacatccaa gcccaactct
     4861 tttgcacgcg ctacaacttc tttactttct tttccaagtt cttttgcgat ttcgtacaat
     4921 cttttcttag acaaatcatg tcctcctctt ctattccata agagacctca ttttctttgt
     4981 aaatccagca tctgttacag ccaaaacctt tctcgatttc ccgactgcta tgcttaattc
     5041 cagtgttgaa aacacggtta caatttctac ttgataataa tgacttttat cttgaatctt
     5101 cttggtcaga ttgggtccag catcatgagc tagaaagacc aacttggcct tgccgtcttg
     5161 aatggccttg accaccaatt cttcacccga tatgatgcgc cctgctcgct gagcaagccc
     5221 caagagatta cttatctttt gcttattcaa gtcccaactc tcttcttttc actttgtgat
     5281 ccacataagc gatcaactcg tcataaaagc tttcttccac ttccatgcta aagctgcggt
     5341 taaagacctt cttctttttc gcctctaggg cttctgcatt gtctagtttg atataagcgc
     5401 cgcggccatt ggccttgccc gtaggatcaa taaagacttg tccttccttg ttcttgacaa
     5461 tgcggagcaa atcacgctta tcaatcactt cgttagacac aacagacttg cgcaaaggga
     5521 tttttcttgt tttcatcttt ccctcctcta gcagctttta ttcttctaca gtatcgtttt
     5581 ctacttccaa ctctactgaa gcagcgtctt ccatggcttc aaattcgcta gcagacttga
     5641 tatcgatacg gtaaccagtc aagtgagccg ccaagcgcac gttttgtcca cgacgaccaa
     5701 tggcaagaga aagcttgtta tctggaacaa ccaccaaggc acgtttgctg tcgttttcat
     5761 caaagataac ttggtcaacc tcagcaggag cgatggcatt gtagataaat tcagctggat
     5821 ctgctaccca ctcgataaca tcgatatttt cttcgattgg taccatgcgg tcatttttag
     5881 catcgtaacg agctgggtgg aatttgctag taatcttctt gatattagca ccaccacgtc
     5941 caacgattgt accgatagca tccacgtttg gattgtggct acgaacagca accttcgtac
     6001 ggtcacctgc ttcacgagcc acgctcatga tttcaacagt tccatcataa acttctggaa
     6061 tttcttgctc cattaaacgt ttgatcattt ctggatgact acggctaaca aagacgttca
     6121 caccacgagg gttgtcttca accttgtaaa cataaacttc gatacgatca tgagaagcaa
     6181 aaacttctcc aggaatttgg tcttgttttg acaattgggc ttcgatgcta ccaaggttga
     6241 catagataaa gcggttgtca aagcgttcta ctgtaccaga catgatttct tgctcatgtt
     6301 ctttgtaagt attgtaagtg atggcacgtg tttgcttgcg cattttttcc atgatggttt
     6361 gtttggcaga ctgggctgct acacgaccaa actcagctgg tgcttcttca aacttgattt
     6421 tgtctccaag ttcataagct gaattaatgg caagagcatc tttcaagctg atttccaaac
     6481 ggctatcaaa tacttcatca acaacttcac ggacagtata aactgtaaag tcacctgttt
     6541 tttcgttgaa gtcaatagct acgctgtctg actgaccata gcgtctgcga taagcggaac
     6601 gaagcgactc tactactgcg tcgatgatat cttctttttt gattcccttg tcttcttcca
     6661 aaatgcggaa ggcctctagc atttctttac tcatgttttc ttcacttttg aatcctcaaa
     6721 agctatcctt tctttttcta taatttaact gctaaacgtg cttttgatac taaactgtat
     6781 ggaatttgga cggttttctt acgcgtcttg tccatatatt ccatagtcaa ctcgtcctct
     6841 tcgaaggcca acaaggttcc ttcaaagacc ttttgcttat cgatggcttg gtagagcccg
     6901 acatggatgt attttccaac cgctccagcg acggcatcct tggttttcaa agggcgttcc
     6961 aaacctggac tggtaatttc taggaaatat tgttctggga agggatctgg cttgatggtg
     7021 tctaggacag gactgataat ttctgtcaag tctgccgtgt cgttcaaggt aattccttcg
     7081 ggtttatcta caaaaatact gagaatcatg tcactgccaa tctttccata ctcgatatcc
     7141 acgagttcaa aaggagcttc tatgacaggt tctacaactt ctctgactaa ttctacgatt
     7201 gttgcgattg cgtccacctc ctcataagca agaggcgaag atatttcccc gcctcacttt
     7261 tcatattctt actatcagta tagcacgttt gccaacttat gtaaagcaaa agcacttgta
     7321 cagcctaatt ttaggctatc tcttaaaatt ctgcctcaac tcggtagata acttgcccct
     7381 tgtttgagaa tttttgctcg tattctgtca tgacattgcc ttcaaaatca ctggcatgca
     7441 aatctaacca gacaccattg agtttcatgc catattgaga aaagctcact aaactgtact
     7501 caaacaagcc acggttatcc gtcttgaaat gaatttctcc attttcaggc aagatacgtt
     7561 tgaaggtatc caagaaggtc ttgtaggtca aacgacgctt ttcatggcgt tttttcggcc
     7621 atggatctga aaagttcaga tacaagcgat caatctcacc gtcttcaaaa tagtcagtta
     7681 agtcagaacc atctacccac aagagcttga tgttaggcac tccaacttca agcaccttgt
     7741 ccaaagcgta gctcaaaaca gacttttgaa tatcaatccc gatatagttg atgtcagggt
     7801 tttgcttggc catacctgaa acaaaggcac cctttccact tccaacttcc acatgaatgg
     7861 gattatcatt gccaaacaag tcccgccatt ttgccttggc ttccaaggga ttgaggacca
     7921 catactgggg atttgcctct agtaattctg ttgccccttt acgatttcta actctcatct
     7981 tctctttcca tacttgtctc ggaaatgacg caaaccatga atctcccgat tgacattttc
     8041 taaatcttgg ttcatataat acttggaaat ctgactcaaa taagacaatt gaccatacca
     8101 atacaattta cttaataccg tttgattgta cttgtaaccg tagtaggtca accattcctt
     8161 ccactgatgt tctgaaatat aatggcagag catatgggcc acatcaaaca tgcgatcggt
     8221 caagcgaacc gaatcccaat ctactaaata aatcaagcca ctatctgtct caatccaatt
     8281 actatgtcgt acatctccat ggacaatggt cgcatggtcc tctctaaatc ctggaatagt
     8341 ctgacgtaaa tcagccatca cttcactgat aaaatgattt ttacgcaaag catctggagc
     8401 cgtttcctgc caagactgta gtaaatctac aggtgtttcc atggcatagc ccaaacgact
     8461 caattgtgtc atcaacggac gtgagcgatg aagacgggtt aaaatattga cgatttgctt
     8521 acgattcata tcataggggg tcaatatctt gcctgtcaac cattcttgag cacacatatc
     8581 acgcccatct gccaaacgac gactccataa taattgtgga gcaatttgtt ctctagctag
     8641 accaggtagg attggagagg tgttcatttt tacaaagatg cgcttcccgt caggatagct
     8701 acccatataa gccttgccac ttttcccagg tatgggagtc agtgttagct cattatcacc
     8761 caaatccatt tctttcctcc gtataaagtt tccttactat tctactagtt tttggcctat
     8821 tcgtcaacca ctctaacccg attctcaaag aaaagcctct ggattggctt gggtatcatt
     8881 atagcttgaa aaaggtaagc accatcttct gcttaccttt tcataatttt tataaataat
     8941 ataggagtgg ccaactgttg taaaacatgt ggactagagt agaaacccat aggttttgac
     9001 tctttttata agcaaagccc agcaacaaac ccccaagtag ataaaaaata aacgaaggga
     9061 cattagaagg tccatgcatg aaagaaaaga gagaggaagt tagcacaagc cctaaccaag
     9121 aattgtcaaa aaccgcacct tgaagaagtc ctctgaaaat gagttcctcc tggatggggc
     9181 caaaaactga ggtagtcaaa atcaaagaca gggaaattcc tctgctgact tccgccaagt
     9241 gttggacccc tgagccagaa gaaacagcga agaaatgaat ataaaccagc gtctcaagta
     9301 cacttagaag aaagattgca atgaaaagca aaagttgttt cttgcttaac atcccaaaag
     9361 aaatcatttc aaactttcta gcataagcaa cactcagcga ggttacaaga agacttacaa
     9421 gaatcaatgc agattcattt tgaaaaaaac ccccatggtt aatcgtataa ggaactgtaa
     9481 tgacaattat tagtactaaa aatccaaaac acaaggcatg aaatttatca aaaaactcca
     9541 taaaactatc ctcctcacca aacagacttc ctacgcgtca ttctttagtt ctagcctttc
     9601 caaaacaaac cattttatac tcttcgaaaa tcaaattcaa accacgtcaa cgtcgccttg
     9661 ccgtactcaa gtacagcctg cggctagttt cctagtttgc tctttgattt tcattgagta
     9721 ttagtaacca aaatccgacc acatagccag cccctatgaa tatagccatt aaagctagca
     9781 tggaatttag gaaattaaaa accaccgcag atacaaaggt tagcacaaaa acattaaaag
     9841 caatggtgtc agaagccaag actagaatat agggtgtcaa ccgatctaaa gttttggaat
     9901 ctaggaaaaa taagtgttta tacatgataa tctcctctat ggctgaaaag caagcctttt
     9961 gtttttttac cccaagaccc tatgtaaaaa agtcagcaaa aatggtaatg ttgcgaaaat
    10021 attattgatc acatgcaccg cataggaagg ataaatgctc ttggtatagc gggtcaaact
    10081 agcaaagatg atgccagatg ttgcaaagat gaagatatct aacaaactag gcaggcttga
    10141 aaaatgagga agagcaaata aaattgacgg aagaagcaaa tcaaggccaa atctcgaatg
    10201 cttaaaaaag gcgtgttgca gtaatcctct atagattagc tcttccataa gtggagtcag
    10261 aaagaacaaa gttatataga tacctagctc agcaaagttg gtcccactat aaccgatcaa
    10321 tacagcccaa ccttcagcag ttgactgaac atgtttagct gtctgaacgt taaaagagat
    10381 ctggagcact accactaata ctgtcaaaat cgaataccaa agccattttt ttcttggaat
    10441 gtgaaagaga taaccatgac ctgtcttaac cagaatccaa atcatgactc cgctaaatag
    10501 caaactcaag aaattttgaa tccagacgaa attgccaatc tgggaagaaa attgccaata
    10561 attttgaata ataagcgtca tctgagaaag accaaatacg aaaaataagt aagagaaaac
    10621 tgcacttatt ttgaatagaa gttgatactt tttcatagaa atcctcccta ctatgacctc
    10681 accttgtcag gctctactgc tgtaagatta agaagacagt ttgttttttt taaggctaac
    10741 ctgactacta gataatagat acattaaggc attaaagaca atgaaaatat gtccatagaa
    10801 taaaatcaac ctcgcatcca aaccaagata aagtttgatt atcaaaaaga tgagcaaaag
    10861 aatttgaaac cataaggttt ttccaaaaat aaatttaaag cgatttcgaa tatctacttc
    10921 cttgattttt accgccaccc ctttattagc aagaaggaaa actcctgctt caaacaaacc
    10981 actgtaaaga acaagccacc caatagatac gatagagatt tgtaaaaatg tccctaaaag
    11041 aatatccaac acactactca agaaaataac aaaaaataat ctgtatttca tattaaatac
    11101 ctccattcat ttatttcact aacaatttaa tagagccttc tactcaaata tcctgtcaga
    11161 aaaggataga aagctacttt ttataatact tcaagcccca catgagcaga agcgtgataa
    11221 acaagcagag aatacaccta tataagcgat tagttgttga tagaattctg tttctgaaat
    11281 acctctatac aaacaaatga caaacataaa atctgccaag ccgataaaca taagttgatt
    11341 ggttctagga ctaaccaaat catcatttac ttatatttaa gagtatctct tttatgttaa
    11401 tgtatgttag cactgaaaag caagacaggc caataatatt taaaatgaac agtaacgggg
    11461 ttaagtctct aaaaaaatta tctactgaca ctacaagaaa tactatacat attatagtcg
    11521 aaactatctt tttcttatcc ataattattt actcctttcc taacaaatcc aacttatcaa
    11581 tcaagagcga tttttaacat aatgtagcag cacccgttgc aactttgaca agtttagtat
    11641 atcattgttt tttaaaattt ttcatccaaa tcttgaattg tcatcgaaac ctcctaaatt
    11701 gcaaaaactt cattagcccc tactttttat aatacttcaa accccaaatg agtagaagca
    11761 tgatgatcaa gcaaagaata gcaccaatat aagcgattag ttgttgataa gattctcctg
    11821 ctgtgatacc tctatacaaa caaataatag acataaagcc tgtcaagccg ataaacatga
    11881 gttgattggt tctaggacta accaaatcat catcttcaaa ctctcttaat ctcatttccc
    11941 tagtaagata aacagtaacc aaaatagaag tcaagttaat aactactaaa agaaattgga
    12001 aaactgacga aatagaaata gataagtaga aacaagcaaa ggcaactgac ccaggaacaa
    12061 tctcacaaag aatatgattc tttttaatca agaaaatctt tcatttcttt tctttctttt
    12121 taattaaaga aaaatagatc ataaccgcaa tcatataggc tatggtataa aatagattat
    12181 accaaatact ctccctaagc ggataaagaa agatggacat gatcagatac agaacgaaaa
    12241 taatcagtat ttttttcttc ataagttttc ctcctaaatg tgcgatttat cttagttgag
    12301 caagaacatt tacactgcta gtatagcact tattttgacc ttggatcact caaatcataa
    12361 atggtcatca aaacctcttg aattgtaaaa attaaaaaag caagcatgaa aaacatactt
    12421 tcctctttat attgtattga taccaacttg tttgtagact tttcatcctg ctatcacata
    12481 tcattttgac aggcgaaaca atattaaaga aactcccctg taaattaagc tagcaaatac
    12541 aggggagaaa tttatttttt agagagtact atccgtatcc tttttggaag attttgaaaa
    12601 tatttttcta attaagtcat ccatataagg accaaatata ccaactacta aaccaataat
    12661 aaaactttta aaatccataa ttaccaccaa catgttgctg cataggctac acctccaagt
    12721 atagctccac ctgcagcacc agttacacct attcctatag caaatggtcc caatagaaat
    12781 gtcaaaccgt tgttgcacac ccatcaattg cgccatatgc aacccctgct gcacaactaa
    12841 tttttcttcc ccaatcaata tctccacctt caacgcaagc aagcatttca ttatccataa
    12901 cagaaaattg tgacatcatt tttgtattca tatagtatgt cacttttcag ttacggaaca
    12961 agtttaatat aaaaattatc aaaaaaacat aggcaataaa gagaaaaatt aatttatcat
    13021 agattagaaa taatatgaca aaacaattca atgatgttaa ttcaatagtc ttttgttttt
    13081 tatcagagat acttatggat agataaataa gataggtttg aaaagcgaag agaataataa
    13141 agaatatagc cttcataaaa tttagctttc atttttatga tgtagcggta taggctaaat
    13201 atccacaaac cactgctcct ccaattcctc ctattgcagc gccccatggt cctagaattt
    13261 tcccatattt cactccaccc gctgcacaac ctaaagcagc aactacagct gctcctccaa
    13321 cacctgcttt ggcaaaatct ccccaattgc atccgccacc ttcaacgcaa gcaagcattt
    13381 cagtatccat aacagaaaat tgtgacatca tttttgtatc catgacaaat actccttttt
    13441 taaaaaacta aaataaatca gaatagaatc ctcataattt tactataagt cttacaaact
    13501 tagtcccaat ttatcaccaa ccatacctcc taagcatgtt aatccacccc caattgcacc
    13561 aatgtgtgct ccaacaaatg caccagcaag tccagctact cctaaagtgg ccaaacctgc
    13621 tccagttcca ccagttataa ttcccgtagt gactcctgta atcagtgcat tttgacaatc
    13681 agtggagcta tacccccctt caactttcgc aagcatttca gtatccataa cctctaactg
    13741 tgacaacatt tttgtattca tgatgaatac ctccttttta ttttcaattt gttaccaaag
    13801 tcttaaattc aataaacaaa tagatttttt ttagtatctt tttgattttc ttaaaaaagt
    13861 atatacgtct actatcttct taaaggtagc agtacctatt ttttagtcta agatttcaat
    13921 aatcttgagt atctaaaata tcttaatttc gttattctcc ttgcaataaa aagttttact
    13981 atactattta ttaacttgca gaaagcaaaa aatattagta aataatagtt tatagttaag
    14041 ttttttattc ctaccaatcc atcaactaag taaagcatca acgattacat aaacgattga
    14101 taatataatt aaaattttgc taactatctt attctcatga ttcttagata actttgatat
    14161 tttgtaagta agtaaataag acagtaaatt aatagcgata ataatactat atttaagaat
    14221 cataatctta caaagaggac ataattcctg aacctacaca aataagtgtt gctgctcccc
    14281 cagttatcgg accagtcgca gcagctaata gtactgctcc aatacaacca ccgattgcag
    14341 atcctaaatt gcctcttcct ccactaacta tttcgagttc ttcattatcc ataacagaaa
    14401 attgttccat catttttgta ttcatgacaa atactccttt tttctttttt tatttttgtc
    14461 ttgttgtaac tttgataagt ttagtatatc atcgtttttt aaaatttttc atccagatct
    14521 tgaattgtca tcgaaacgtc ttgaattagg ttttttattt caagccacct ctaaatgttt
    14581 aaaaaaaaat aatttctaat cactttttta ccattcagga agttttaatg actattcaag
    14641 atttcataaa atatgaactt agttttatga cataatagac ctatccacta tatgaaagga
    14701 attgccaatg acttcttata aacgtacatt tgttcctcaa atagatgcga gagactgtgg
    14761 tgtcgctgcc ttagcctcga ttgctaaatt ctatggttca gatttttctc tagctcactt
    14821 gagagaactt gcaaagacca ataaagaagg gacgactgct cttggcattg taaaagccgc
    14881 tgatgaaatg ggctttgaaa caagacctgt tcaagcagat aaaacgctct ttgacatgag
    14941 tgatgtcccc tatccattta tcgttcacgt taacaaagaa ggaaaactcc aacattacta
    15001 tgttgtctat caaacaaaga aagactatct gattattggt gatcctgacc cttctgtaaa
    15061 aatcactaaa atgtcaaaag aacgcttttt ctatgaatgg actggagtag ctatttttct
    15121 agctaccaaa cccagctatc aaccccataa agataaaaag aatggtctac taagcaagct
    15181 tccttcctct gattttcaaa caaaaatctc tcattgctta cattgttctc tcaagcttat
    15241 tggtcactat tatcaatata ggtggttctt actatctcca aggaatcttg gatgaataca
    15301 ttccaaatca gatgaaatca actttaggaa tcatctcagt tggtctggtt atcacctata
    15361 tcctccaaca agtcatgagc ttctccagag attatctcct aaccgttctg agtcagagat
    15421 taagtattga tgtgatttta tcctatattc gccatatttt tgaacttccc atgtctttct
    15481 ttgcgacacg tcgtacagga gaaatcattt cacgattcac agatgctaac tctattatag
    15541 atgccttggc ttctaccatt ctttctcttt ttctggatgt ttctattctg attcttgtag
    15601 gaggcgtctt actggcacaa aaccctaatc tcttccttct ttctcttatt tccattccta
    15661 tatacatgtt catcatcttt tcttttatga aacctttcga aaaaatgaac catgatgtca
    15721 tgcaaagtaa ttctatggtt agctctgcca ttatcgaaga tatcaacggg attgaaacta
    15781 taaagtcgct cacgagtgaa gaaaatcgct atcaaaatat agacagcgaa tttgtagatt
    15841 atttggaaaa atcctttaag ctcagtaaat attctatttt acaaacgagt ttaaagcagg
    15901 gaacaaaatt agttctgaat atccttatcc tatggtttgg cgctcaatta gtcatgtcga
    15961 gtaaaatttc tatcggtcag ctgattacct ttaacacact tttttcttac tttacaactc
    16021 ctatggaaaa tattatcaac ctccaaacca aactccaatc tgcgaaggtc gctaataacc
    16081 gtttgaacga agtctatcta gtcgaatctg aatttcaagt tcaagaaaac cctgtccatt
    16141 cacatttttt gatgggcgat attgaatttg atgacctttc ttataagtat ggttttggac
    16201 gagatacctt aacagatatt aatctcacga ttaaacaagg agataaggtt agcctagttg
    16261 gagttagtgg ttctggtaaa acaactttag ccaaaatgat tgtcaatttc tttgaaccct
    16321 acaaaggaca tatttctatc aatcatcagg atattaaaaa cattgataaa aaagtcttgc
    16381 gccgtcatat taattaccta ccacaacaag cctatatctt taatggctct atcttggaaa
    16441 acttaacttt gggcggtaat catatgatta gccaagaaga tattctaaga gcttgtgaat
    16501 tagctgaaat tcgtcaagac attgaaagaa tgcctatggg ctatcaaact cagctctctg
    16561 atggagctgg tctatcagga ggacaaaagc aacgaatagc cctcgctcgt gctcttttaa
    16621 ctaaagctcc tgttttaata ctagacgaag ctactagcgg tcttgatgtc ttgactgaga
    16681 aaaaggttat agataatctt atgtctctaa ctgataaaac cattctcttt gtagcccatc
    16741 gtctcagtat agccgaacga accaaccgtg tcattgttct tgaccagggg aaaatcattg
    16801 aagttggtag tcaccaagag ttaatgcagg cgcaaggttt ctaccatcat ctattcaata
    16861 aataaggaga atgtcatgaa tcctaatctt tttagaagcg tcgagtttta tcagagacgt
    16921 taccataact atgcgacagt gttcattata cctctttcat tactatttac tttcatcttg
    16981 attttctccc ttgttgccac aaaagaaatt actgttactt cccaaggaga aatcgcccct
    17041 acaagtgtca ttgcctccat tcagtcaacc agtgataatc ctatcctagc taatcattta
    17101 gtggcaaatc aagtagttga aaaaggggac ttactcatca aatactctga aacaatggaa
    17161 gaaagtcaga aaactgcctt agcaactcaa ttacaaagac ttgagaagca aaaagaagga
    17221 cttggaattt tgaaacaaag cttagaaaaa gcgactgatc ttttttctgg cgaggatgaa
    17281 tttggctacc ataatacctt tatgaatttt actaaacaat cccatgatat tgaactgggt
    17341 atcacaaaga ctaacaccga agtttcaaat caagctaatc tttccaatag cagttcatca
    17401 gctattgaac aagaaattac aaaagttcaa caacaaattg gagaatatca agagttgaga
    17461 gatgctatca taaataacag agcacgctta ccaactggca atccgcacca gtcaattttg
    17521 aatcgttatc ttgtagcctc acaaggacaa acacaaggaa ctgcagagga gccattttta
    17581 tctcaaatta atcaaagtat tgcaggtctt gaatcatcta tcgcaagcct caaaattcag
    17641 caagctggta tcggaagtgt agcaacttat gataacagtt tagcaaccaa aattgaagta
    17701 ctccgcactc agtttttaca gacagcctca cagcaacaac taactgtgga gaatcaatta
    17761 acagaattaa aagtacaact agatcaagcc acacagcgtt tggaaaacaa taccttaacc
    17821 tccccaagta aaggtatcgt tcatctgaac agcgaatttg aaggtaaaaa tagaattcca
    17881 actggtacag aaattgctca aatattccct gtcatcacag atacaagaga agtactaatc
    17941 acttactacg tatcttctga ctatctacct ctactagata aaggacaaac tgtaagatta
    18001 aaactggaga agattggaaa tcacggcacc accatcatcg gccaacttca gacaattgat
    18061 caaactccta ccagaacaga gcaaggaaat ctctttaaat taaccgctct tgcaaaacta
    18121 tctaacgagg atagtaaact catccaatat ggcttacaag gtcgcgtcac tagtgtaact
    18181 acaaagaaaa catattttga ttatttcaaa gataaaattt taacccattc tgattaattt
    18241 tcagataaca ctctataact atttattatc ttatcaaaaa ggagaatcat aacatggata
    18301 agaaacaaaa cctaacttca tttcaagaac taacaactac cgaactcaac caaattacag
    18361 gtggaggatt gtgggaagat ttattatata acattaatag atatgctcat tacatcacat
    18421 aagaacttca tcatccaata caactataaa aaaataagac cgagaaacaa gtactctcgg
    18481 tcttattttt catcattctg tatgtatcac agtaagtacc tgacgaaaga cttgattttg
    18541 acaggtggta tttagactgg tattaggatg gctttccaca atcttcatga cggtatagag
    18601 accaactcct ctctcctccc ctttagaact ggctccaaag gagaagattt cagaaatatc
    18661 gatgccctct tctttgatgg agttttcgat gataaaggtc tcctgtgctc cattttttaa
    18721 aaaggcgatt gaaacatgag gttgactagc ttccacactg gcttcaatag cattgtcaca
    18781 aaggatagac acaatggtta gaaaatcaag tagactcatc ccctcgacct gaatctcctc
    18841 aggaacttcg acattaaaga caatgttctt atctctggct tttaaaaatt tccctgctag
    18901 aagacttttg agggctttat cacgaatatt taccaatctg cccaggtcat atttattgtt
    18961 ctgcaatttc tgactggaat cctttaagac ggagccatag acctctttta tctgctccat
    19021 atcctcctct tcaatgccca gacgtaagct agtcaagagg ttggtataat catgacgaaa
    19081 gctccgtact tccttgtaaa gctcctctat atgccgacta tagcgttcca tatctctata
    19141 gcgcagggcc tgctcttgtt ccaatctctc atagagtttt tccttcaaat aggtatccaa
    19201 tttcttgata acccccataa aaaagagtag gtaaaagact aggatgagat ggcgaacagt
    19261 ctttgattga atactttgtt catattcaaa aaaagacaga ctttccatga ctagatagta
    19321 gccacccatt atccagttaa tctgagtcag ggacttttga aaggctttat cgagaatctc
    19381 ctttctcaag ctagtaaaat cgtagtccaa ccatttcaaa aaagctagag aaatgaagaa
    19441 attgaaaatt attatacata acccagtaaa tgagtagcca tcatatactt gcccttgtcc
    19501 caaaaatgga agcacaaaat aggagactcc tctataaaag agattcacca atatcattgg
    19561 aaagagacca taaaagaaaa ggagtttttt aggaagccct ctcaataata agaaagataa
    19621 gcctatgccg tacaagggtt ccataaaata agataggtaa acatttccta ctatatagct
    19681 aatcatcaca aaaacaaagg ccaacagtat cttaaaaaga aaggccttaa aaatcctctc
    19741 gaaagtaaga tcaattccat ccaccttaaa gaagatgaca atttctagtc cattagtaac
    19801 aagtgtatac aacaatatcc aagcaatgtt cataaattct cctagctcag tgtaatttat
    19861 tgatggcctc agacacttcc ctgaccttat aacgggcgat tagacaactt ccaccattgg
    19921 gaaagaaaag cagtttttct ttcttatcca aatgcaccac atttgcagga ttgatgagaa
    19981 aagagcggtg gcactgcaag agacggggct cctgcttgaa aacctcctct aaactcgctg
    20041 taaattccag cctgtctgtc ttggtataga gaataacacg atgggctctg ggcgacgttt
    20101 cgagatagta aacctcttta aaaggatact gaaattgggc aaattttgat ttaaagtaaa
    20161 agcaatcttc cgccagactt ttactatctt gactattggc atagaggagg gctgtctcga
    20221 tccgagattc aaactcctct gctgacaagg ccttatcaat gtagtccaaa gcagacactt
    20281 ggtagcgaaa agacaggggc ataaactccg agtgagtcgt cacaaagaca atcagggcat
    20341 aaggatcccg atcccgaatc tttctagcca cttccagtcc cttcatctct tcatttcgaa
    20401 tctcaatatc caaaaagaat agctgatggg cccccttctc atgcacttca gccagcagtt
    20461 ggtccggctt gccaaatacc tcaaaagagc taggaatgat atgatgtgct ttcaaaagtt
    20521 tctcaatcgt cgtttcaatt ctagtctgtt gggaaaaatc atcctctaaa acaaatattc
    20581 tcatcttctt actctccctc tttcaaccat ttttgacgaa tttctctata gcgacgtctg
    20641 gcatacttga cagcgtattg accttcttct ccgagaaaaa ggattctttc ttgaaaatca
    20701 atcgatttta atttatcaag attaaccaaa caatttcgat gacatctcat caaggtttcc
    20761 ccacattggt tctcaagatt acttaaattt tgaagcatat taaaactagc ttcttctgta
    20821 acaatctgta cggtatgggc tttagttgga tgtgtttgga tatagtagat atcgtcgatg
    20881 tttactttat agactgtttt ctgcgtctga ataatcatat atttcattgg attctcctcc
    20941 taagaaaaga ataacagaaa aggtctagcc caagcacacc caatcctaaa cagtctttga
    21001 aaactcctaa aaggattatt ttctacaaca tcatgatgag cttacaacta ttttatcata
    21061 aaattcactc agcgcaattc aagacatttc aatgacaatt aaagatttga ataaaaaaaa
    21121 agaattaaaa gtgataaact aacagtatca aaacacagtt gccagaagta agactggcac
    21181 ccagattaaa ggaggcattc ccatgacaga tacagacccc atcaaaagag ctcatacttt
    21241 gattactgac ttaaacaaag cctaccaagc atgcaaacag gcaagcgctg acgacgtccg
    21301 ctttcaggag caattaaact ctattcttgg ttttctagcc aaggctgaaa cagtggataa
    21361 tcgattcttg attgaactag aaaaatttta ccagacttcc agtcttctca tgggactcag
    21421 cgctcttgat ccagatgctc caactcgcgc cgcttggcgg gcctatgacc gcttccactt
    21481 tgaccaagtc aagaccaagt taatactcaa tgaaaatcaa agagcaaact aggaagctag
    21541 ccgcaagctg tacttgagta cggtaagacg acgctgacgt ggtttgaaga gattttcgaa
    21601 gagtataagt ctctacggac caaccattat cctgtagtaa caaaaaagaa gttgagacag
    21661 actgaactca acttcttttt tagtgtcgta tcagcaatgt tagtcctgca tctgacgttt
    21721 tacctgataa ggcaaataca agactagtaa aaccaaacca gctcctagta aggctagaag
    21781 ggctagtttt tcttggaagg taatcaaccc aacaactaat tccacaagta aaacaaaact
    21841 ggtcaatcct cgaactacct cctgtaagcc tttttccttt tgccccttgt ccagcggaaa
    21901 gagttgggtc aaatactggt agtcaaaggc atgatagagg gccagcaact ggaagagcaa
    21961 gaggtagtta aagagaacta ccactgctgt cgcaatccaa gcttgctcga taaaaacctg
    22021 cgccagtacg gaaagtaaga gaagacgaag actgagagca aagaggtcgc catttcgcag
    22081 ataagaacgc agatagagat tttgccaaat ctttccagac accttctgaa cagcctttaa
    22141 gataaagtcc agataggcac gacgtttgac actgtttgaa attcccttta cctgcgtaaa
    22201 gagggcaaag aaacgaagca agacttgctt acgcttgctt tcttgggaaa tgacatagtc
    22261 ccagtccagc ccagtttcag tgaaaaattt gctggccttt tgacgaaagt ggaaatattt
    22321 tcctaccccc aataaaagca catagagcag aaaaactggc aagccataac ccattgctaa
    22381 aaataaaggc gcaaataaca gcaagaaaag ggtctgtaca aagagccaaa agactaggga
    22441 aatgccagtt tgacgcttga gatggagctt gatttcctct tctccaacta agagaaagag
    22501 cttgtctgga gcctccatat aggtggcaat tcctccccaa agtaaaagta aaacagacgt
    22561 aattcctaca aacaaaagga taggccaatg attttcagga aaatgttgta agagttgact
    22621 gtactggtag gctagaaagc ccaacaggac aagcaggaac aagacaaagt ggtcattgag
    22681 cacatagcgc agataaccaa ggcactcctt acgaaaggcc tgctttctct ttaaaaacaa
    22741 gtctttcata gatcctcctc tttggtcaga gccaagtaaa tatcattcaa actagcctca
    22801 ggcatatcaa aggcttcacg tagttgcagg agattgcctt tggcacgcac ctctcccttg
    22861 tgaagaatga caaaggcatc acacatcttc tccgccgaat ccagcacgtg ggtactcatg
    22921 agaatagact tgcccttttg cttctccact tccaaaagct gaatcaaatc agaaatagcc
    22981 agcggatcaa gaccaaggaa aggctcatcc acgatgaaaa gacttggatc caccacaaaa
    23041 gcacagataa tcatgacctt ctgcttcatc ccttttgaaa aatgaacagg gaaccagtct
    23101 aatttctgtt ccaaacggaa catttttaac aagggctcta ctcgttcgaa agccactttt
    23161 tgctcaatac cgtaagccat agcaaccgtt tcgatatgct ctctgagggt caattcctca
    23221 tacagactag gcgtctcagg aatgtagcca atctgcttgc ggtagctagt cgcatctcct
    23281 tgcagagtca ggccattgat attgatggag ccactataag gtgccaacag accgataatc
    23341 tcattgatcg tcgttgattt cccagcacca ttgagaccaa tcaaaccgac caactgccca
    23401 ctttcaacag taaaggacac atctttcaaa acagggacat gaacatagcc acctgtcagg
    23461 tttttaattt ctaacatatt ttctccaaat ctggtataat gtagctatat tatatcaaaa
    23521 ttcagtacag tagaggtaga ttttatgtca gattgcattt tttgtaaaat catcgcaggg
    23581 gaaattcctg cttcaaaagt atatgaagat gagcaggtcc ttgcctttct tgatatctct
    23641 caagtaacac taggacacac cttggtcgtg ccaaaagaac actatcgcaa tcttttggag
    23701 atggatgcta cgagcgccag ccaactcttt gcccaagtac caaaagtagc tcaaaaagtc
    23761 atgaaagtca ctaaggctgc tggtatgaat atcatttcca actgtgaaga agtcgctggt
    23821 caaacagttt ttcatactca cgttcacctt gtacctcgct acagtgctga cgatgacctc
    23881 aagattgatt ttatcgccca cgaaccagac tttgacaaac ttgctcaagt cgctgaaacc
    23941 atcaaaaacg cttaaggagt tgctatgaaa ttatccaacc tactgctatt tgcaggagct
    24001 gcagccggaa gttatctggt cacaaaaaat cgccaaacca tcacagatga agtcttgaat
    24061 accactgacc gcgttcaagc tatcaaggac gatgtggata ttatccaaaa cagcctgcaa
    24121 atcattgacc agcaaaaaga acttatcaag gaataccaag aagacttgac ttacaagttt
    24181 aaggtcttgg aaaaggatat ccagactaga ctagctgtga taaaagaaat gcagggaact
    24241 gaagataagt aaaaagagcc ccccggctct tttttaaaac gtaaacaagt tatagtgaat
    24301 tgaatttaga atagcacatc atagtttcta aagcattgtt agagattact ttaaaatcct
    24361 cttatcaatt tgttcatatt ctatttcaat ctactatata tatcccatca actatgcatc
    24421 ataatttagg taactcatac tcaataaaaa tcaaaaagca aactagaaag ctaggcacag
    24481 actgctcaaa acaccgtttt aaggttgtgg atagaactga cgaagtcagc tcaaaacact
    24541 gttttgaggt tgtagatacg actgacgaag tcagctcaaa acactgtttt gaggttgtgg
    24601 atagaactga cgaagtcagt aaccataccc atgacaagcc gacgctgacg tggtttgaag
    24661 aaatttttga agagtatcat tcaccatttc acaactaaat cgaagacttt ctgccgtaat
    24721 gaaaacacct gaaacagctt ggtttcggct gtccggaaac tttaagactt aggttcaaag
    24781 tttaggtatg gaacttcgaa ggaggtcgct accgtccgtc attacttagg aaagtcttaa
    24841 aaaatcggct ctataaagta aaaagagccc gacagctctt tttgtttata ttcaatgaaa
    24901 atcaaaaagc aaactaggaa actagccacg ggctgctcaa aacactgttt tgaggttgta
    24961 gatacgacaa gccgacgctg acgtggtttg aagaaatttt tgaagagtat tattctccat
    25021 caaaggcatc tttaatatgg tcaaagaagc cttttttctt tggatttact ttcaagtcac
    25081 cagcagccgc gaattctttc aaggctactt tttggcggtc gttcaagcct gtcggtgtta
    25141 cgacattaac agtaacgtat tggtcaccaa ctgcaccgcc acgaaggctc ggtgccccct
    25201 tactacgtag gcggaatttc ttaccagtct gagttccctc tggaataacc aattcaacat
    25261 caccgtgaac agttggaata tctactgtat caccaagagc cgcttggaca aagttgaggt
    25321 tgagattgta gaagatagtc gttccttcac gttcaaactt gtcgctagct tctacagaaa
    25381 ctactacata caagtcacca taaggtccac cgttaaagcc tgcttcacct tgaccagcga
    25441 ggcgaatttg ttgacctgtt tccacaccag cagggatttt cacatgtacg ctatgagctt
    25501 gtttctcatg acctgttcca tgacaggttg tacatggata tttgatttct tttcctcgac
    25561 cgtgacagac atcacaggtt acttggcgac gcatcatacc aagaggagtc tgcgtatcga
    25621 cgttaatgac accagcgcca tgacagcgtc cacaagtgac tggacttgtc cctggcttag
    25681 caccagagcc attacatgta cgacagccag cttcacgatg atacttaact tccttctcag
    25741 ttccgaagat agcttcttca aaggtcaaat tgacacgata ctggagatca tctccttggc
    25801 gaggagcgtt tggattgcgc gaagaaccgc ctccgccgaa gaaacttgag aaaatatcct
    25861 caaaaccacc gaaaccacct gccccattga aaccgccgaa accaccagct ccaccaaaac
    25921 caccattggc gcctgcagca ccatactggt cataggcagc acgtttttgg tcgtcactca
    25981 aagtctcata ggcttcttga acttccttgt acttgtcctc agcaccaggc tccttgttga
    26041 tatctgggtg atattttttg gaaagcttac gataagcctt tttgatttcg tctgccgaag
    26101 cgtttttgga tacccccaga cgatcataaa attcagtatt gttcataatt caagatacaa
    26161 agggcgtcaa acggacacag ccatctagga gttttgacga cggacgctta cgtcctagaa
    26221 aaaactatct tttgggcaca gtccgtagcc cgtgttcagt tacgaacacc cttattcctt
    26281 tctattgatg ttctgaatcg aaccaccatt taggtcgggt tcaattcctt tcttttatat
    26341 ttagtaagaa attctgaaac ccgtgttcag ttacgaacac tctttgttcc cttctattga
    26401 tgagacaaaa cccaaacaaa tgagattccg tcccttttta tcgaaaaaca gaggctgggt
    26461 tgcaacctct gcaaataagt aaattaactt tattttgatt ttaaatatcc tataagtaca
    26521 gaaatattta tatatttttg tctcttctta gtatttgcct atataattcc aattgatcat
    26581 aagaaataca actactgtcc aaatcatacc aattatgaac ggtattacaa atttatatgt
    26641 ttgtatttct aatgatatca tagctggtac catcgccgat acaaatgcag acaacaatac
    26701 tgaggtaaca aaattcctta ccgcttcatc atttttgata caactatcat gttcagctaa
    26761 tataatttct ctatatctag ctaaatattc tattggaata ttatcaataa aatcttttga
    26821 tgttctatag ttatcagctt gattacaaaa atcattataa acttttcgtg tattttttag
    26881 atactcttca tccaatacac tcatcttact tttccgtaaa ctctccgtct acgacgtcat
    26941 cgcctgcgtt ccctgttgct tgtgcgcctt ctgctccttc ttgagcttgt tgcgctgctg
    27001 cggcttgttc gtagagttta acagcaagtc cttgagcttt ttcgttcaat gcttcaagtt
    27061 ttgttttcat gtcgtccaag ttgttgtctt cttgagcttt cttaaggtca tcaagggcag
    27121 cttgggcagc gtcacgttct gcgtcgaagc ctttaccttc agtttccttg attgtctttt
    27181 cagtcgcaaa gattgcttgg tctacttcat tacgaaggtc tacttcttct ttacgtttct
    27241 tatcggcttc agcgtttgct tctgcatctt tcatcatgcg gtcgatttct tcgtcagtca
    27301 aacctgagtt cgattggatg acaatagttt gttctttttg agttccaagg tctttggcct
    27361 taacagacac gataccgttc ttgtcgatgt caaatgttac ttcgatttga ggaattccac
    27421 gaggtgcagc tgggatatca gtcaattgga agcgtccaag agtcttgtta tctgctgcca
    27481 ttgggcgttc accttgaaga acgtggatat caacggctgg ttggttgtct gctgctgttg
    27541 agaagacttg tgatttagat gttgggattg tagtgttgcg atcgataagt tttgtaaata
    27601 ctccacccat tgtttcgata ccaagtgaca atggcgttac atcaagaagg acaacgtcct
    27661 tgacatcacc agtaatcaca ccaccttgga tagccgcacc catagcaact acttcatcag
    27721 ggtttactga tttgtttggt tctttaccag tttcagcttt aacagcttca acaacggcag
    27781 ggatacgagt tgaaccacca acaaggataa cttcgtcgat ttctgacaag ctcaaacctg
    27841 catctgaaag ggcttgacga actggaactt ttgtacgttc aacaaggtca cgagtcaaat
    27901 cgtcaaattt cgcacgagtc aaagtcattt ccaagtgaag aggtccagcc tcacctgcag
    27961 tgataaatgg caagctgatt tgtgttgaag ttacaccaga aaggtctttc ttcgcttttt
    28021 cagccgcatc tttcaaacgt tgcattgcca tcttgtcagt agacaagtcg ataccgtttt
    28081 ctttcttgaa ttctgctacc aagtggtcaa tgattttttg gtcaaagtcg tcaccaccaa
    28141 gtttgttgtc ccctgcagtt gacaatacgt cgaagacacc gtcacccaat tcaaggatag
    28201 agacgtcgaa tgtaccacca ccaaggtcaa ataccaagat tttttcttct ttgtcagtct
    28261 tgtccaaacc ataagcaaga gctgctgcag ttggttcgtt aacaatacgt tctacttcaa
    28321 gaccagcaat tttaccagcg tcttttgttg cttgacgttg agcgtcgttg aagtaagccg
    28381 gaactgtgat aacagctttg gttactttct caccaaggta gtcttcagcg tagcctttca
    28441 agtattgaag gatcatagct gagatttctt gtggagtgta ttcttttcca tttgcagaaa
    28501 ctttttcaga agttcccatc ttagatttga tagagataac tgtatctggg tttgtaactg
    28561 cttgacgttt tgcagcatca ccaacgatga tttctccgtt tttgaatgag actacagatg
    28621 gagttgtgcg gtttccttct gggtttgcga tgattttgct ttcagttcct tcaagaactg
    28681 caactgctga gtttgttgta cctaagtcaa taccgataat tttagacatg tgtttttctc
    28741 cttgttagtt aattttctat ttttcttttt gatactcttc ttaagtggcg acgccgtcag
    28801 agcttgactt cgtcagtctc ttttactaaa ctttgagcct aaggtctcaa aatttgcgca
    28861 aatagcgcca cggcgaagag tatcgtcttt ggttcgcttc gctcactatt acaaagcaaa
    28921 acatatttta tctttcttca tagtttattg tcgtttcgga caagttttct attatgtaaa
    28981 ttgcgacacg aggagtcgaa atcgatttta tttcgacgac gagttagtaa ggaagctagg
    29041 caaacgccat agcaattgcc gttttctgac gagttgcttt agctaccgtc agaattgccg
    29101 aatcgaacac gccctaagct ctgagtaaaa aagatagatt ttcttgtgtt catcgaacac
    29161 ttcgtcaatc tcctattttt actgcgagct ttttacgggc tttgtatctt agttatacac
    29221 cactaccatt gctgggcgta ggatgcggtc atggagtttg tagccttttt gaaagacttg
    29281 ggcgatggta tctactgggt gttcatcgtc tgctgggaga gtttggatgg ccatatggta
    29341 gttatggtca aattcgccat ctgctgcgat ttcttcaatt ccttcttctt tcaaagcgtg
    29401 aatcaagctt tcttgcacca tccccaagcc cttcttcaca tcatctgtca aaccttcaac
    29461 tgcaagtgca cgctcaaggt tgtcaagaga tggtaagatt gcttttgcca agtcctggct
    29521 acgataacgt tgcaagtttt gacgttcttc attggcacgg cgttggatat tttgcatttc
    29581 tgcatgagcg cgaagatatt tgttttcgaa ctcatctgca cgttcatttg ccaagtccaa
    29641 ctcagacttt tcaggagttg tttcttcagc tgtttccaca acttcctctt cttgaacttc
    29701 ttctacttct tcatttttta tatcttgggc catgttcgcc tcctttaatg atttcaatct
    29761 taatgtactt cgtaatgatt actgctgagg tagcggtaaa aatctgtcaa cttcatggtc
    29821 aaaacacggt tgaccacatt gatttgattg attagctgtt ggtaatccag attaactgga
    29881 ccgataatgg ctagaattcc aactccccga taaggaatga ggaacttact actaatcacc
    29941 gctaggtcag ctaaacagga ctcttgaccg tctgcaacac gaacattttg catctgatcc
    30001 tcacgcaacc cctcacgaat ctccaaggcc accttttgcg gttggtcaaa gaactgatag
    30061 gctgctagat tggcaaaatt caagagattg accttgcccg ccatcacaat gttttcgttg
    30121 aacatttcct taaagatgtg ttcaaagaga tcgatgacat tatccgttgt tgtaaagtaa
    30181 cgctggataa tctgcggaat ctccgtccga atcttgtagt gaatatctaa aacggtgtga
    30241 ccgaggaaac gttcctgaat gatgctcttc agtttcagca aatcctcctg caagaagttc
    30301 cttggaatca gaaactgact agtaaccgtt cgcgactcgt ctagggtaaa taccgccaag
    30361 gctgtatgtt gccccaaaac aacgatatca aaggctgtca aacgttgcct gctcggctca
    30421 acatccagtg ccactaccgt acagccactc aggtctgtta gcaagttagc agcctcttgc
    30481 agaatatcct ccaatttgaa gaattcctga tcaaaggctt tgacaatctc atatacctca
    30541 ttttcagcca gtcggtcaaa atccagtgag tgtttcacat agtactgaaa accagcaaca
    30601 cttggcatcc gaccgcttga agtatgagcc ttctcaagca acccttgttt ttctagttcc
    30661 gccatgtcat tacgaatggt tgcactgcta gagttaatag actcttgcaa ggcttttgat
    30721 ccgacaggtt cgtgcgtttt ggtaaagatg tcaataatca gatttaaaat atcctgctga
    30781 cgctctgtaa ccatctcatc actcctctct gtctgatcaa ttagcactca atgcatccaa
    30841 gtgctaactt atgattctat tatacaccct tagaagagaa tgtcaagaca aaaactcaaa
    30901 aaattagcac tcttttataa agagtgctaa aaatcaatct gaagacctag aaccttgcta
    30961 ttcatctact cggtatttcc tttttagtct gaaataacca tgaattagat aagaaatcag
    31021 aaaagcatat aaaacaaaaa taagaaagaa agacatagaa agatcctctc taaacaaact
    31081 catacaaaca acaagaccac ctaagaaagt agctatacag gaacgaagtc tagatcgcat
    31141 aacttcccat ttgagcccct tactcatata gacttgatcc tctggaagta aatcagaaga
    31201 cgatttacga agaatcgaac aagaacctgc tcctatcaat tcccaacctc tatctctaaa
    31261 atcttgcagt tcacgcttat gctctttaag aaatctagaa tcatagatac gatagataac
    31321 atcgtccggt tgaccttgct caaaatagaa caaaccaaaa cgactagttc tatacctcca
    31381 acctttcaaa tgcatctcat gtaaatattc ttctttcttg tccaaatcaa caatggtgaa
    31441 aatccgaaat tctactctgc tattcattgt cttaccccaa aattagaaaa catgcctagc
    31501 gttatttatt agataattct ttccactttt gactcaatct ccaaaaaata taagaaatct
    31561 gaatcgcaaa aactatcaat aaaacccaat ctattatgaa aatcaaaaac acttcccaac
    31621 tgaaagaact acctccagtg acaaactttg agaaaaacgg tagtagagct aaaaagagaa
    31681 gcaaaatagg aagcatccgc attgttaaaa tccttttggc ataaaaaaat ctttatttaa
    31741 acgaaaatat tatggcaaaa tttacgccag tttttgaacg gctgatgtag atattttata
    31801 ctttcaaaat gtttaaatgt gattatttat ttttgaaaaa tagctcacca gcccgactga
    31861 aagtgcttat agaatgataa taagtcgcct gccgaaaaca gcgaaaaata gcagtgttat
    31921 gcggagataa tctgacgcga tgcgaaagta tattgcatac ttattttcaa caatttagca
    31981 gagtattttt ataagtgtga tataatagaa gtataatttg ttctgatagt ttattttatg
    32041 gagaagtaga tttttagaat gcggaggatt caatatggtt gagtttataa agtctaagaa
    32101 agaaatgagt gaggaggata ttaaagcaaa tttcatcact cctgctattg tatccaaagg
    32161 atggaaaaat ggtgagcata tcgcttacga agaatacttc actgatggtc gaattgaagt
    32221 tagaggagat aaggctcgtc gtaaagaagg aaaaaaatca gactattcac tgtattacca
    32281 atttggaact cgaattgcaa ttgttgaggc aaaggataat aaacacagcg ttcgagcagg
    32341 attacaacaa gctattgaat atggagagat tttagatgtt ccatttgttt attcttcgaa
    32401 tggtgatggc tttattgaac acgaccgtat cacgagagaa gaacgtgagc tggagttaga
    32461 cgaattccct actcgtgaag aattattttc tcgtatgacg aaggaaaaag gattgacgta
    32521 cgaaattaca gaagctatct caactccata ctatacagac gccttctcaa tgaaaacgcc
    32581 acgctattat cagcaaatag ctatcaaccg tactattgaa acagttgcca gaggacaaaa
    32641 acgagtaatg tttgtgatgg caacaggaac ggggaaaacg ttcatggctt ttcaaattat
    32701 tcatcgcctt cgaaaagctg gtttggctaa acgagtttta ttcttagcgg atagaaacat
    32761 cttagtagac caaacgatgg ctgaagactt taagccattc gaaaaggtaa tgacgaaaat
    32821 tacaccaaaa cttttgactg ctcctgaaaa attaaattct tttgaaattt atctagggct
    32881 ttatcagcaa ctaactggtg aagatggaac tgaaacacat tatcaaaaat ttgataaaga
    32941 cttctttgat ttaatcgtaa ttgatgaagc gcaccgtggt tcagctaagg aaaacagtaa
    33001 ctggcgtaag ataattgatt atttcagttc tgcgacacag attgggatga ccgctactcc
    33061 taaagaaacc aagaatgctt ccaatacgga atactttggt gagccaatct atacttatag
    33121 tttaaaacag ggaatcgagg atggtttttt ggctccatat cgtgttatga gggttaattt
    33181 agatgtggat gtggatggtt atcgtccaga aactggaaaa gttgatacta acggacaatt
    33241 aatagaagat aggtactacg gcaggaaaga ttttgataaa accattgtca ttgatgatag
    33301 aacgcaaaga gttgccaagt ttgtttctga ttatatgaag caaaacaatg cacgatttga
    33361 taaaacaatt gttttttgtg ttgatattga ccatgccgag cgaatgcgtg ctgcacttgt
    33421 aaaagagaat ctagacttag tccaagaaga ctatcgttat gtcatgcaag taactggtga
    33481 caacgctgaa ggaaaagctc aactggataa ctttatggat gtcaattcta attttcccgc
    33541 tatggtaaca acgtctaaat tattaacgac aggagttaat gctaaaacat gtcgtttgat
    33601 tgttttagac tctaatatcc aatccatgac tgaatttaaa caaattattg gtcgtggcac
    33661 acgtctttat cctcaaaagg ggaaagaatt ttttacgatt attgattttc gaaatgttac
    33721 caatttgttt gctgaccctg attttgatgg tgagccagtg aaggtgctgg aaacaggtgc
    33781 gaaaacagtc agtggttcca cgcccggttt cgtagatgag gaaggtgacc cagtagaaaa
    33841 atatatcgtt acagacaagc aggttaccat tcttaattct actgttcaag tattggatga
    33901 aaacgggaaa ctgattaccg aaagcctgac cgactacact cggaagaata tcttaggtag
    33961 ctacgccact ttgaacgatt ttatcacagt ttggcatacg gcggataaaa agaagcttat
    34021 cttagacgaa ctttataaaa aaggagttta tctagatgct attcgagagt cggagggaat
    34081 atcagaacaa gaaatcgatg attttgattt actcctaaaa cttgcctatg gtcaaaaaga
    34141 attaaccaaa acggaacgta tcaataagct caaacaaagc ggatatttat ataaatatag
    34201 tgaggaagcg cgtgctgttt tggaaatttt actgaacaaa tacatggata aaggtattgg
    34261 agaactcgaa agcattgaaa cattaaaact tccagaattt cagatatatg gtggaacctt
    34321 caaaatcatc aatacttatt ttggagataa aaaacgatat ttacaagcaa ttaaagaatt
    34381 ggagcaagag ctatttacag tagcttaatg aaaggaaagt atgtcaatta catcatttgt
    34441 aaaaagaatt caagatatca ctcgaaacga tgctggtgtt aatggtgatg ctcaacgtat
    34501 tgagcaaatg tcttggttat tattcttaaa aatttatgat agccgtgaaa tggtttggga
    34561 attagaagaa gacgagtatg agtcaattat cccagaggaa ttaaaatggc gaaattgggc
    34621 tcatgctcaa aatggggaac gggtattgac aggcgatgaa ttacttgatt ttgtcaataa
    34681 caagttattc aaagagttga aagagcttga aataacttca attatgccta ttcgaaaaac
    34741 gattgttaaa tcagcttttg aagatgcgaa caactatatg aaaaatggcg tcttgttacg
    34801 ccaagtcatc aatgttattg atgaagttga tttcaatagc cctgaagatc gtcattcgtt
    34861 taatgatatt tacgaaaaaa ttcttaaaga tattcaaaat gctgggaact caggagaatt
    34921 ttatacgcca cgtgcagcga ctgattttat tgccgaagtt cttaacccaa aacttggaga
    34981 atcaatggca gaccttgctt gcggaacagg aggcttcttg acttcgactc tgaaccgttt
    35041 aagtagtcaa cgtaaaacta gtgaagatac caaaaaatat aatacagctg tttttggtat
    35101 tgaaaagaaa gcatttcctc atcttttagc agttacaaat ctgtttcttc acgaaattga
    35161 tgaccctaaa attgttcatg gaaatacttt ggagaaaaat gttcgtgaat atacggatga
    35221 tgaaaaattt gacattatta tgatgaatcc accttttgga gggtcagaat tagaaacaat
    35281 aaaaaataac tttccagcag aattacggag ttctgaaaca gctgatttat ttatggctgt
    35341 cattatgtat cgtttgaaag aaaatggtcg tgttggagtt attttacctg atggttttct
    35401 atttggtgaa ggtgtaaaaa ctcgcttgaa acaaaaactg gtagatgagt tcaacttgca
    35461 tacgattatt aggttgcctc atagtgtctt tgcaccgtat acaggaatcc atacgaacat
    35521 tcttttcttt gataaaacaa agaaaacaga agaaacttgg ttttatcgtt tagatatgcc
    35581 agatggttat aaaaatttct cgaaaactaa gccgatgaag tcagaacact tcaatcctgt
    35641 tcgtgactgg tgggaaaatc gtgaagagat tctggaaggt aagttctaca aatctaaatc
    35701 atttacacct agtgaattgg ctgagttgaa ttataattta gaccagtgtg gctttccaaa
    35761 agaggaagag gaaatcttaa atccctttga gttgattcag aattatcaag cggaaagagc
    35821 aactttaaat cataagattg ataatgtatt agctgatatt ttgcagttgt tggaggacaa
    35881 ataatgacac cagaacaact taaagcaagt attctccaaa gagcgatgga agggaaatta
    35941 gtgccgcaaa atcccaatga cgaacctgca agtgaattat taaagagaat taaagctgaa
    36001 aaagaaaaac ttatcagtga aggaaaaatc aaacgagata aaaaggaaac tgagatattt
    36061 cgtggtgatg atg
//
LOCUS       DBERCW010000020        35196 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.020, whole genome shotgun sequence.
ACCESSION   DBERCW010000020 DBERCW010000000
VERSION     DBERCW010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35196
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.020"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(525..1214)
                     /gene="rplA"
                     /locus_tag="ACL72M_001209"
     CDS             complement(525..1214)
                     /gene="rplA"
                     /locus_tag="ACL72M_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGS0716338.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1422..1847)
                     /gene="rplK"
                     /locus_tag="ACL72M_001210"
     CDS             complement(1422..1847)
                     /gene="rplK"
                     /locus_tag="ACL72M_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGS0716339.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1970..2686)
                     /gene="ldcB"
                     /locus_tag="ACL72M_001211"
     CDS             complement(1970..2686)
                     /gene="ldcB"
                     /locus_tag="ACL72M_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGS0716340.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2704..3165)
                     /locus_tag="ACL72M_001212"
     CDS             complement(2704..3165)
                     /locus_tag="ACL72M_001212"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS0716341.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3167..4204)
                     /locus_tag="ACL72M_001213"
     CDS             complement(3167..4204)
                     /locus_tag="ACL72M_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGS0716342.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4302..5627)
                     /gene="brnQ"
                     /locus_tag="ACL72M_001214"
     CDS             complement(4302..5627)
                     /gene="brnQ"
                     /locus_tag="ACL72M_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGS0716343.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5798..6085)
                     /locus_tag="ACL72M_001215"
                     /pseudo
     CDS             complement(5798..6085)
                     /locus_tag="ACL72M_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6245..6823)
                     /locus_tag="ACL72M_001216"
     CDS             complement(6245..6823)
                     /locus_tag="ACL72M_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGS0716344.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6877..8277)
                     /gene="pepV"
                     /locus_tag="ACL72M_001217"
     CDS             complement(6877..8277)
                     /gene="pepV"
                     /locus_tag="ACL72M_001217"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGS0716345.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8290..8895)
                     /locus_tag="ACL72M_001218"
     CDS             complement(8290..8895)
                     /locus_tag="ACL72M_001218"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGS0716346.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9066..9866
                     /locus_tag="ACL72M_001219"
     CDS             9066..9866
                     /locus_tag="ACL72M_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0716347.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10050..10883)
                     /locus_tag="ACL72M_001220"
                     /pseudo
     CDS             complement(10050..10883)
                     /locus_tag="ACL72M_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
     gene            complement(10873..12720)
                     /gene="uvrC"
                     /locus_tag="ACL72M_001221"
     CDS             complement(10873..12720)
                     /gene="uvrC"
                     /locus_tag="ACL72M_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGS0716348.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGSIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12760..13461)
                     /locus_tag="ACL72M_001222"
     CDS             complement(12760..13461)
                     /locus_tag="ACL72M_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGS0716349.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLAGQ
                     FLSVTVRLNHYYLSNPHYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13540..14772)
                     /gene="murN"
                     /locus_tag="ACL72M_001223"
     CDS             complement(13540..14772)
                     /gene="murN"
                     /locus_tag="ACL72M_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGS0716350.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEYFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14777..15997)
                     /gene="murM"
                     /locus_tag="ACL72M_001224"
     CDS             complement(14777..15997)
                     /gene="murM"
                     /locus_tag="ACL72M_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGS0716351.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16109..16888)
                     /locus_tag="ACL72M_001225"
     CDS             complement(16109..16888)
                     /locus_tag="ACL72M_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0716352.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16957..18618)
                     /locus_tag="ACL72M_001226"
     CDS             complement(16957..18618)
                     /locus_tag="ACL72M_001226"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS0716353.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18793..21015)
                     /gene="recJ"
                     /locus_tag="ACL72M_001227"
     CDS             complement(18793..21015)
                     /gene="recJ"
                     /locus_tag="ACL72M_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGS0716354.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GGASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21292..22095
                     /locus_tag="ACL72M_001228"
     CDS             21292..22095
                     /locus_tag="ACL72M_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0716355.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     EVADRIIFMADGEVLVDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22135..22899
                     /locus_tag="ACL72M_001229"
     CDS             22135..22899
                     /locus_tag="ACL72M_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS0716356.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQGDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     EFNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22912..23589
                     /locus_tag="ACL72M_001230"
     CDS             22912..23589
                     /locus_tag="ACL72M_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0716357.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23599..24258
                     /locus_tag="ACL72M_001231"
     CDS             23599..24258
                     /locus_tag="ACL72M_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0716358.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNSVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24554..25744
                     /locus_tag="ACL72M_001232"
     CDS             24554..25744
                     /locus_tag="ACL72M_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGS0716359.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26065..26946)
                     /locus_tag="ACL72M_001233"
     CDS             complement(26065..26946)
                     /locus_tag="ACL72M_001233"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGS0716360.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27087..28415)
                     /gene="vncS"
                     /locus_tag="ACL72M_001234"
     CDS             complement(27087..28415)
                     /gene="vncS"
                     /locus_tag="ACL72M_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGS0716361.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28412..29068)
                     /gene="vncR"
                     /locus_tag="ACL72M_001235"
     CDS             complement(28412..29068)
                     /gene="vncR"
                     /locus_tag="ACL72M_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGS0716362.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29117..29200)
                     /gene="pep27"
                     /locus_tag="ACL72M_001236"
     CDS             complement(29117..29200)
                     /gene="pep27"
                     /locus_tag="ACL72M_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGS0716363.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(29380..30759)
                     /gene="vex3"
                     /locus_tag="ACL72M_001237"
     CDS             complement(29380..30759)
                     /gene="vex3"
                     /locus_tag="ACL72M_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGS0716364.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30811..31458)
                     /gene="vex2"
                     /locus_tag="ACL72M_001238"
     CDS             complement(30811..31458)
                     /gene="vex2"
                     /locus_tag="ACL72M_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGS0716365.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31471..32748)
                     /locus_tag="ACL72M_001239"
     CDS             complement(31471..32748)
                     /locus_tag="ACL72M_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716366.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGNSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33105..33275)
                     /locus_tag="ACL72M_001240"
                     /pseudo
     CDS             complement(33105..33275)
                     /locus_tag="ACL72M_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(33418..34017)
                     /locus_tag="ACL72M_001241"
     CDS             complement(33418..34017)
                     /locus_tag="ACL72M_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716367.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYTTIDKTSDATALLKLKLNNVDNQPATEVLSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     VGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            34380..35196
                     /locus_tag="ACL72M_001242"
                     /pseudo
     CDS             34380..35196
                     /locus_tag="ACL72M_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9974 a         8026 c         6495 g        10701 t
ORIGIN      
        1 cccctctcac accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc
       61 atgtcgttca aggtaataat ccaaacacga aaccagtcca cgtttttcaa ggactggttt
      121 tgatatagca cgtttaagta ccgacttctg agctactata gtagattgaa actagaatag
      181 tacacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgaa cgattcgtcc
      241 tattcttatt tcattttatt ataattgata gtggtcgccc cagccagata ccttatccgc
      301 tatataggcc ttattatcac gttcctgttc gtagagccac gatttcgcta tcccttcctc
      361 tgacgattct tatttccagc gtcagacttg ggaatcgcta ttgggttcac cggtagtagg
      421 tgcccaccga ggacttacac ctcagatata cgacatgccc gtcgtacatc aaaaaaagtt
      481 gagacatagt gtcttcaact tttttacatt actttaacta ctgattaaag tgagtttacg
      541 tcaactttga taccaacacc ttgagtagtt gtgatagtca agtttgttac gtaagttcct
      601 ttagctgtag ctggttttac tttttggatt gtttcgttga aagctttaaa gttttcaacc
      661 aatttttcag cttcaaatga tactttaccg atgattgctt gaacgttacc tgcacggtca
      721 gcacggtaag tgattttacc acctttagac tcttcaactg ctttagcaac atccattgtt
      781 acagtaccag ttttagggtt tggcatcaag ttacgtggtc caaggacacg tccaagacgt
      841 ccaacaagag ccatcatatc aggtgtagcg ataactacgt cgaagtccaa ccaaccgtcg
      901 ttgattttag caacaaggtc atcttcacca acaaagtctg caccagcagc ttttgcttct
      961 tcagcttttg caccacgtgc gaaaacaaga acacgtgaag ttttaccagt accgtttggc
     1021 aataccattg ctccacggat ttgttggtca gcttttttaa cgtcgatgtt caagttgtaa
     1081 gcaacttcta cagttgcatc aaattttgca aagttagttt cttttgcaag tgctacagct
     1141 tcttctacac tgtatgcttt tgtgctgtcg attttctcaa gagcagcacg aagttgtttg
     1201 ctttttttag ccattttcta ttctccttgt aagtggttca atcgattttc atctcccacg
     1261 tcacttctcg aaatgatgaa gtcttgcggg ttttcagtct actatttttc tcttcctacg
     1321 gccttaagct cccttgctgt atccaagtac aagcctcagt cacttgccta gtatgaaaag
     1381 caactaatag actgctgtga gattttctac tgtgttattg attagtcaac aacagtgaat
     1441 cccatagaac gagcagtacc ttcgatcata cgcattgcag actctacgtt tgctgcgttc
     1501 aaatctggca tcttagtttc tgcaatttct tgtacttgtg cacgagtaac tgtagcaact
     1561 ttagttttat taggtgtacc tgatcctttt tcaacacctg cagctttttt caaaagaaca
     1621 gcagctggtg gtgttttcgt aacgaaagta aatgatttat cttcgtaaac tgagataaca
     1681 actggaatga tcataccagc ttggtcagct gtacgagcgt tgaactcttt tgtgaatccc
     1741 atgatgttga taccagcttg accaagagca ggtccaaccg gtggagctgg tgtagcttta
     1801 ccagcaggga tttgcaattt tacaagtttt tcgacttttt tagccatttt taaatcctcc
     1861 tttgtggttt tggcggtaat tagagatttt tacctcccac aagtatgctt tacacatacc
     1921 tttccattat acactattta tctaaaaatg caagagaaaa ctttcatttt taatcgacat
     1981 aatcgccgcc ttcaaagcca tagtactctt ccaaactgag accacttgca gcaatttctt
     2041 tggcttcttt tccaacgtag cggagatgcc attcttctgc catgtagcca gtctcctttt
     2101 ccttgccttt aagatagcga acaacaaagc catagtcagc cgcatggtcc aagagccact
     2161 gggctgcctt ttcttcagta actaaatccc catctgtccc aatcaaatca aaagcaagac
     2221 ccgtctggtg ttcactgtaa cctgggcgtg ctgagtagcg atctgctgct tccttaccat
     2281 cttgattgac atagtcttgg tagagcttag cctgagtttc ataactccta aacccactgt
     2341 attggtcact gattggatag ccctcagcct gcatagctgc gattagtttg agcaactctg
     2401 ccttggctgt tggattttct cctggattgt aatcttttga caaaggataa cgtttattag
     2461 ctaggataat ctcatcgtat ttcccttgga tactataata gctcccttta ttgctaactt
     2521 ctgccttttt ctgactagaa gcttgagatt tgctacctac agttccttcc ggttgactgc
     2581 tttgctccgt tttttgagtg ttttcttcaa ctttggtttt ttcttgcgaa caagctgcaa
     2641 gggtcaatgc tagtaaacca gataaaatga catatctttt tttcatttct ttcttcctct
     2701 ctcttaggcc aaatacttct ccaattcatg agataagatt ttaatcatct cttccagctc
     2761 tggcgattgt acttggcaat cttctgccgc catttcttcc cagggcaccc accagactgg
     2821 gccacggcca ttcaaaccgt gactcttcat atcacctgct cttcggggaa aaagatgcca
     2881 atgagcgtgg gcatcgccat ttcctaggag ttcaatattc atcttttcag cctcaaatgc
     2941 tttggcgact gcttcttgga ctaaactcat ttcctctaaa aagcgaagtt ttacagaagt
     3001 ttccatatga tggagttctg tgacatgatc ttttgctaaa aataaggtat agcccttaaa
     3061 gtattggtag tcaccaataa caacatagcc tgtttctagt tcttttacaa agtagggatt
     3121 ttgcccagct ttaatgagtt cgattctctg acagattaag cacattctat gataccgcct
     3181 cgctcttaag ataagcatca accatacgct cagtcgctat tactgaatcg atgtgggtgc
     3241 gctcataaga gtgactggac tcaataccag ctccaagaag tgcatgcttg acctctgcac
     3301 ctgctgacat cgctgctgaa gcgtccgatc cgtaaaatgg atagatgtcg agcttaaatg
     3361 gaatatcttg ctctttagcc aaggcaacca agtgttgacg gaagtcatag tgataaggac
     3421 ctgaagcatc cttgacacag atagatactg tgtactcatc tgtctgctgg tcatctccca
     3481 tagctcccat atccacagcc agatattcta ctacctgagc aggaatgtta gaattagcac
     3541 catgtcctac ttcttcaaaa actgaaaaag caaaatgagt tgttactggc aattcaatct
     3601 tctctttctt ataaatacga agcaggttga gcaaaatcgc tgcgctgacc ttatcatcca
     3661 aatgacgaga cttgataaaa cctgtatcag tcacaacagt tcgtgtatcg aagctgataa
     3721 aatcaccgac ctcaatccca agagcacgag tttctttttc attgcttact tttacatcca
     3781 aacgcacttc catattgtcc tgcgtgcgtt ctgcagttcc tgcatccttg tagacatggc
     3841 aagaagtttg gtggatgagg atggttcctg ataccttttg acctgtgcta gccacatgaa
     3901 cggtacagtt ttcaccttca atcatgttcc aaggaaaacc accgatacgg tccaatttaa
     3961 gacgaccatc tggtttgaca gcacgaacaa tagcacccag cgtatccaca tgggcagtca
     4021 catagcgatg ttgctcatca ttttgacctt tgatggtcac attgacacca cccttagctg
     4081 tgcgaactgg ctggtaacca aaaccttcta gagtcttgac taaataattc gaaatttcac
     4141 gagtgaagcc cgttggcgat gcgatggctg tcagttcttt gatatattct actgtttgat
     4201 tcatttcttc acctctttcg ctacctatta taacacattt atcatcggat aaaaaaagaa
     4261 aatcactcct gtagacttgg ctacaaaagt gatttaagtg attattccat ttcaaaaaca
     4321 tcgctttctt gcttgtttgg tagaaccaat gagagcaaga ttccaacaat ggctggcacc
     4381 aaccatggga gagatgcctt ggcaaaagga agaacgctaa caagatttgc aagaaactca
     4441 accttaaacg agcttcctag tacgcttgca atggcaataa ctgtaaccac agcaattgtc
     4501 aactgcatac ctggttttga aagggcaaca aatttgttga caatgacaat cataacgata
     4561 gcaatcgtga ttgggtacaa gataaccagt actggaattg agtacttgat aatcgcatca
     4621 agacccaaat tggcaatagc aaatccaatc aaggtaaagg ctgtcgcata aaccttgtag
     4681 ctgatttgtg ggaagcgctc attaaagaac tcagctgttg acacaatcaa accaacagtc
     4741 gttgtgaagc aggttacggt aaccatagct gcaaggaaga gttgagctgt tgagccaaag
     4801 atttcttgag tggcttgtga caagatgtaa acacctggtg ttccaccctt catcgcttca
     4861 gctggtactg ggaaatgatt tccaagaaaa cctaaaccga tgtaaagagc gctgaaggca
     4921 agggcaacaa cgataccaac aacccaaata gttgaaatgt attctttctt acttgaaaat
     4981 ccaagttgtt tcaaggtttg aactgcgatt acgctaaagg ccactgaagc aagggcgtcc
     5041 aaggtattgt aaccttctag gaaacctgta ccaaaggcag aagcttgata agcagctgaa
     5101 gcagcttgag gacttgttcc accatatttg atagctccca gaacgaccaa gataacaatc
     5161 aaaattgcaa agactggcgt taaaacacgt ccaatgcggt ctaagatttt tgatggatta
     5221 agcgaaatca aataggctgc cgcaaaatac agaaccgtaa atacaatcaa gccaagtcct
     5281 ttatttgcat ccgacaaaag ggggctaatc cctacttcgt aagctgttgt agcagtacgt
     5341 ggggtagcaa agaatggacc gattgacaag taaagaactg agaggtaaag agtcgcaaac
     5401 caaggcgcta tcttcgttga aatctcgtag atatatcctt taggatttag cgttccaata
     5461 ataagggtca agacggcgat accaacgcct gaaaagacaa aacctgcgat ggcaggaaga
     5521 aaatgttctc cagatagagc acctagagaa ggcggaaaaa tcaagttccc cgcaccaaaa
     5581 aatattccaa acaggagcaa acctgttagg gtaccttttt tagccataaa aatctccttc
     5641 atatttataa aatactgacc tagtatacca cgattaggag tctgaaaaaa gcatcacgag
     5701 gcaaatatta aatgttttca attttcttaa aaataagaat tatctaaaaa taaaactctc
     5761 ctacccagtc cacaccaagc aggagaaatg caaaatttta aagttcttca aaggctaaca
     5821 tgccaccctg gacattgata acattataac cttgttctaa caggaattgg caagcacgcg
     5881 ccgatctcat tccagatttg caaataatat aatgcaagcg atctttgtcc aattaatcat
     5941 aactatcagc caattgacta agcggtaggt tgtgggcaca ttctaaatga agagctgcaa
     6001 actcatccac ttctctcaca tccactagag aaagctggtc gttttggtaa agctggtaaa
     6061 atgcgtcaaa ggctatttct ttcattcttt ttcttctaat actcttcgaa aatctcttca
     6121 aaccacgtca gcgtcgcctt accgtgcgta tgttaccgac ttcgtcagtt ttatctgcaa
     6181 cctcaaagct gtactttgag cagcctacga ctagcttcct agtttgctct ttgattttca
     6241 ttgactataa aatggtttta attctttttt tcaaatctgg cactacttct gcctcaaacc
     6301 aaggattttt ggccatccag atttgatttc gtggtgatgg gtgaactagc ggaaaatagg
     6361 ctggcagata gtctttatag tgtttcaccc tctccgttac cttcccactg attttctcct
     6421 gtaaatagta ggcttgggca tattgcccaa tcaagagggt taactgaata tcaggcaatt
     6481 cctgtaagag ctgcggatgc catttttctg caaaacctgt acgaggcgga agatcacccg
     6541 acttgccatg tcctggaaag tagaaatcca taggcaaaac agcaaaataa cctgaattgt
     6601 aaaaggtatc ttcatccaca cctagccagt cccgcaagcg gtcaccactt ttatctttcc
     6661 agtaaaggcc tgcttcttga gttttaagtc ccggagcctg accgatgata ttgatgcgag
     6721 cagtttttgg cgctgcaaag agaggctcaa tgccacgctc tgtatagctg gcattctgtg
     6781 aatccgccat gatagcctgt ttgattcttt cgatttgaga catctacttt ccctccaaaa
     6841 agaagtccaa gcataagatc tcagacttct atcgttttat ttgatcaatt cgtaaatagc
     6901 ttcggcatag attgctgctg ctcggaagag atcgtccaag gcgataaatt cattggcttg
     6961 gtgcatggta tcaattgagt ctgggaacat agcaccatag gcaactccgc gctctaacaa
     7021 gcgaccaaag gttccaccac cgatgacttg ttcatgacct ttaaagccag tttgtttttc
     7081 atagatattc aacaaggttt gcacaagtgg atcttccatt ggcacatagt gaggcgtgtg
     7141 accgtgttca gacaggctaa cagaaacaac tggcaagttt tcaaggattg acttgatttg
     7201 ttctggactt gttccttttg gatagcggat gttgagggca atggtattat cagcacttgt
     7261 ttcatcgaag cggaagacgc cggcattcat agaaagagca cccatctttt catccacatg
     7321 agcaatctta agattttcac cctcatgatc gttcaagaga attttacctg cgatgtcaag
     7381 gtagtctttg gctggaccag caaagccaaa ctgactgagg aagagggcaa ggtaagttgc
     7441 gccattgaca cctgaagcag gcatagcacc gtgggctgat ttaccaatga tcgtcacctt
     7501 gtatttgcca gcttcttctt ggagttctcc tctaagtttg tgttctgcaa caaaggcatc
     7561 tagtttagct tgcaagtcag ccaagtcacc tgaaacgact gctgttgctg attctggtac
     7621 catattttca cgtaaaccac ctgtaaagct gtgaagacgg gcaacacctg tattttctcc
     7681 tgcaaagtgg aggtattccg tgatatttcc tttttcacca ttgatgattg gaaattcagc
     7741 atctggtgag aaaccgaaat ctggtttggc aagtcctacg tgctcaaagt agtagtccat
     7801 gtctgcccag cctgattctt cgtctgttcc aacgatgaag cgaactttct tagaagttgg
     7861 aagacccaat tctttgatga ttttcaaacc atagtaacaa gctgttgtag gacccttatc
     7921 gtccgaagcc ccgcgcgcat aaaggcgacc atctttgata gttggtgtgt aagggtctgt
     7981 gtcccaaccg ctaccagcag gcaccacatc catatgggca aagattccga gaacttcttc
     8041 tccatcacca aactcaaaat gtcctgcata gttatcaaca ttcttagttg ggtagccatc
     8101 gcggtctgcg atttcaagga atttctccaa ggcttttact ggaccaggcc caaatggatg
     8161 ctgggcatca gccttgctgt catcacgttc tgaattgatt tccaaaaggc taaacaagtc
     8221 agccaagagg tcttctttgc gtttttctac ttctgctgta aaatcaattg ctgtcatttt
     8281 ttcttctttc tatcttttct cgatgatttc atctactggc aagcggtagc ttggttccaa
     8341 tttttcgtct gtataaccca ctgtgatcaa gagttctggg cggaaacggt cttcgatttc
     8401 caaaacttca ttaacttttg atttgtcaaa accaagaata atgttagaac caattccttg
     8461 gtctgtcaat gcaagaacca agttcatggc aaccaaacct gcattgagag ctaggtagtc
     8521 gctgacttgt tgttcattgt agcgtgcaaa ttcagctggc aaatttttca tgaagtattg
     8581 aagttgttct tctgagaaat tgttagcacc accaactcgg gcaatcttac gagcgcgttt
     8641 ggcaaggtct gtatctgtaa atagggcaat ggttacaggt gctgatgata cctgctcaaa
     8701 gtttgaacca taagccaact ttgccagttc agcatttttc tcacgaacaa ctacaaattt
     8761 ccaaggctgg ctgttgtggg cgcttggcgc caaggttgca atttcgatag ccgtacgcac
     8821 atcttttgga tcaacaggct tatcagtgaa atgcttggtc gcatgacgtt ttttatttaa
     8881 ttcaagaaat ttcataatcg atttcctttt ctaattctac tgcttccatt ctaccataat
     8941 ttgaaagagc ttgcagggat ttttcatgat taagtttttc tatcacagac ataaaagata
     9001 tatattggtt tatcaggaaa gtttctgata aactagcaag tactttacat ttgaatggag
     9061 acagtatgaa aaaatttagc ctattactag ctatcctacc atttttggtt gcctgtggga
     9121 atcaagctac acccaaagag actagcgctc aaaagacaat cgtccttgct acagctggcg
     9181 acgtgccacc atttgactac gaagataaag gcaatctgac aggcttcgat atcgaagttc
     9241 taaaggcagt agatgaaaaa ctcagcgact acgagattca atttcaaaga accgcctggg
     9301 aaagtatctt cccaggactt gattctggtc actatcaggc tgcggccaat aatttgagtt
     9361 acacaaaaga gcgtgctgaa aaataccttt actcgcttcc gatttccaac aatcccctcg
     9421 tccttgtcag caacaagaaa aatcctttga cttctcttga ccagatcgct ggtaaaacaa
     9481 cacaagagga taccggaact tctaacgctc aattcatcaa taactggaat cagaaacaca
     9541 ctgataatcc cgctacaatt aatttttctg gtgaggatat tggtaaacga atcctagacc
     9601 ttgctaacgg agagtttgat ttcctagttt ttgacaaggt atccgttcaa aagattatca
     9661 aggaccgtgg tttagacctc tcagtcgttg atttaccttc tgcagatagc cccagcaatt
     9721 atatcatttt ctcaagcgac caaaaagagt ttaaagagca atttgataaa gcgctcaaag
     9781 aactctatca agacggaacc cttgaaaaac tcagcaatac ctatctaggt ggttcttacc
     9841 tcccagatca atctcagtta caataacact cttcgaaaat ctcttcaaac cacgtcagct
     9901 ttatctgcaa cctcaaagct gtgctttgag caacctacgg ctagcttcct agtttgctct
     9961 ttgattttca tattgagtat aagatatatt aaaagcgatg ggatcagcca atcgcttttt
    10021 tagtttgcat tggttatttt aggaaactct tacaaaaaat caaaaaaatt cttcacatcc
    10081 tctacatacc tatgcttttc tattaagctt gctaatagtt ccagattgtg cctctgatag
    10141 ttatcttcac gacgtagttc ttcatacatt tcgataaagg gaaaaccctt ggatttggca
    10201 aattctaact cagcctcgta atcataagcg actttacgaa ataggatatt taccaattcc
    10261 ccatcttcaa cctctatcac ggcatactgg gcacggtgat tttttaacgc ctcccaatta
    10321 aaatagggca tgccaatcga ccctggattg atgatttgtt gcccttgact accataacga
    10381 agcaactact tgtgaacatg accataaact gccacgtccg tttccgcatc tagcagttgg
    10441 tcaaatttct ctgtatcatt ctcaactagc aagtcaccac catagttttt gtcaggtaaa
    10501 ttatgagaga tagaaaagcg caatccgtca atttctttct tttccagcaa aggcaagctt
    10561 cgtagccaga caatcgttgc aggatccatt cgctccatca aatactgtgt catacgcaag
    10621 agctgaactt cctgtgggtc ttctaagcca tattgcccat ctaaagcctc aaggacacaa
    10681 tcatcccaat tgcctcgaac acttgccgtg ataggaagtt cctttaacag agcgaccaag
    10741 tcatttgcac ctggaccagg gaggaaaatg tctcccatga gccaatattc actggctcct
    10801 tgagttttag catctgcaat cactgcttct agcgccgtcg cattgccatg aacatctgat
    10861 aaaattgcga ttttatggtt tattgtggtt tccttccgtt tggtaatcta ctctttcttc
    10921 cgccacttga agcaagattt ctgtttcctg cgggttcaac ttggtttgca cagcctctgc
    10981 tactgctctt ggtactccaa cttcgacaat ctcatccaca ctggcttcct tgattttggt
    11041 cagagacttg aagtgcctca tgagattttg cttgcgttta ggtcccagac catcaatccc
    11101 atccaattga gatgagaaag aatttttgga gcgcagttgg cggtggaagg taatggcaaa
    11161 gcggtggacc tcatcttgaa tgcgttggag gaggaaaaat tcctgagaat tgcgagacaa
    11221 gtccaccact tccagcggat ctccaaagag caattcatgg gtttggtgct tatcattctt
    11281 ttgcagacct gcaattggaa tatccaagcc cagttcttct tggatgactt gcttagcaat
    11341 attgacttga ccttgccccc catcaatcac aatcaaatct ggaggagtca aagcctcacg
    11401 ctgtactcga ccatagcgtc tgcgaatgac ctctcgcata ctggcatagt cgtctggccc
    11461 gactacggtc ttgattttat acttacggta atctttttta cttggcctgc cgttaacaaa
    11521 gaccaccatg gctgaaacag gactggtccc catgatgttg gagttatcga aggactcgat
    11581 gcgaactgga gtcggaattt ggagcaaacg tcctagattt tcaatagctc cttgggtctt
    11641 ttcgactgat ttttctagca ggttaaattt ctgctccaga ctaacacgtg cattttttat
    11701 ggctagattg accagctgtt ttttctctcc acgttggggt ttgagaatct tggtatccac
    11761 caaagccttg acagcttctt cgtcaatatc ctgcggaatc agtacctcat tgggaactag
    11821 gtgagatttt tcttgataga attgtcccac ataggtcaag aaatcctcat ctggatcatt
    11881 gaagtagggg aagagattga catcgcgctc gatgagcttg ccctgacgaa caaagaaaac
    11941 ctgcacacac atccagccct tatccacata gtagccaaag acatcgcgat tttggagatc
    12001 cttagccatg acccgttgct tggttcgaag cgttccaata gcctgaatca ggtcacggta
    12061 ttccgccgca cgttcaaact ccatagtctg ggctgccgct gccattttgc cctttagctc
    12121 atcaatgatt ttgttatcct gccctttcag aaaatcagaa acctcctggg ccatagactt
    12181 gaaataagcc tcatccttct tacagatggt gtgagccata cactggccga tatggtaata
    12241 aaaacagacc ttagagggcg ggttggtaca cttacgaaaa gggaatatcc gatccagcaa
    12301 ccgcttgatt tcattggctg cccccacatc gggatagggt ccaaaataaa gacctccgtc
    12361 ctttttgacc tgacgagtga taatcaagcg tggatagcgc tcattggtga ttttgatgaa
    12421 aggataggac ttgtcatcct tgagcatgat attgtacttg ggcttgtttt ccttgatcag
    12481 gttgatttct aggagaagtg cctcaatatt agactccgta acaataaatt caaaatccac
    12541 aatttcagac accagagcct ctgtcttggt atcatgactt ccacgaaaat aggaccgtac
    12601 tcgattacgc agatttttag cctttcctac atagataatg gagccatttt tatccttatg
    12661 aatgtagcaa ccagggctgg tcggcaagag ctctagtttt gatttaatca agttgttcat
    12721 agttccatta tagcaaaaaa agtagggaaa gatagtaccc tactcactag tctcatatat
    12781 ttttcggagg tttgcaacat cctcttcctg gataccataa aaggaacctg ctggttgcat
    12841 gacagacttc tcatctgtat ggtccaagcc aatcgcatga cctaactcat gttctgccgt
    12901 atggacaagg cgttcatagg agtagccata gtgtggattg gacaaataat aatgattcaa
    12961 ccgcaccgtt acggacaaga attgccctgc taagagatta gtttgacttt ccgcctctcc
    13021 tgccacagga gtgcctccgt cgttcatctc cgtagccgta atatccgcct tactagactc
    13081 agtcacgagt tcaaagttaa aagcaccagt ttgattccag ttctggattg cttctaaata
    13141 agcctcttga aagcgtgaat ccatctgcgg atccaggtaa atacgagcag aggcctgtgc
    13201 ccaccttcct tcagaatgct ggtgactatc tgtctggctt aacttaggca gttgccctgt
    13261 tttctcccat tggtcaatac tttgttgacc aatttttact gaccgttctg cttgctttag
    13321 cgctccttga aaatccccgt tcagatacca gagaagtccg aaagcaagca cacataagag
    13381 cacaactatc caaaccagac gccaaaacaa acgccacaca aaagaaaaga aagcccctat
    13441 caaacgaaaa agccagcgca tgtctctcca cctttctagc aaataagaat tattttacta
    13501 aaagaagcta aaagaaatct aaatactgac tttttcatct taacgtccta ctattttttt
    13561 gagtaactgg atagctttgt attttaaagg cgatggatgg taacggaaag tacccgcttt
    13621 gcgtacaata tagccattaa aattctgttt aaaacgcaaa acaccatcac ttccatcaaa
    13681 aatcccttga atgcctagga aattgtattt aggtattcca cgttttatgc tttccaacat
    13741 aacatatttt tgaagcagtg caggggcata gaacttatta aactcagtgt aggaaccact
    13801 aaagagataa gtcgtttcct gaggcatata aacaaataaa ctcccagcta aaacaatatc
    13861 ttcttctcca tatttttcaa tcaagtctcg cgcttctgct tttcgaactt caaacgtttc
    13921 aaattgacta gaatattctc tcagttgatt ttgttttttc tcagaatgag gatttttact
    13981 caaatcaagt cgcaacttgt ccaagttttc ttctagttta ctttgttcac cttgcaattt
    14041 gctcatatac tccgaaaaat tcaagcttgc tatgagaaac tccgcttgtt ctccaaaagt
    14101 atcataaaaa tactcataat attctaaact tttatcacta tattctctac gttcagaggt
    14161 ttcttttgtt atattcttaa aaatcgatag ttcttcacgt tttaactttt tcaaccgaat
    14221 gccaaaggtt tcagcctttt tcaccaaggg tttacccttt ttgctaaaac ttttaagcaa
    14281 actcttttca gttaattcag ttaaatcttt atagtataac caatctggtt ctccacctgg
    14341 gtaacctgtt gttaagccat caaattgata acctaaatca gtcaaacctt gaataatact
    14401 ttttttctca gcatctattg gattaccttg gctatcaaaa gtttgataag tttcataagg
    14461 ttttacaagc aactctaata caccattttg cttggcatat tcttttaact ctgcataaaa
    14521 aactggaaga gcatcttgtt gggtataaat cggccccgaa ttgagttcca tatgcagacc
    14581 acccagcatg ggcaggctat aaaccagagc tgcaacttga atttctcctt cttgtttcaa
    14641 agcaagataa acaattcgag cccctctttt ttctagcaaa tcccccatct ggacagattg
    14701 cataaaggaa cgagaagaaa cctgatcaga ataagtctga aactcttctt tcgtgagtgt
    14761 tgttagtgcc atatacttac tttctatgtt tttttcttaa tgttttacgg aaatcaagag
    14821 caagtcttaa cagaggatag agaggatgag tgggcattgt aaattcaccc aagtattctt
    14881 caatcgttgg attaaatttt tccttaaaat gataaagtcc accattgaga gagttttcaa
    14941 caccacctaa attttgccag accatacctc gctcaaaggc atagcgagcc gtttcatacc
    15001 atgttaaaat tggtgcattg taacgtttaa aatcatcatc cataccagca tatatattga
    15061 cagaggtagt accaaattcc aaactcaaag tagccgctaa aggaactctc gcttgaccta
    15121 catctatata ttcctgcaag aaggtcaatt cctctaacaa acgttctttt tccttcttct
    15181 gcgcttctac ttttgaagtt cgagtcgact cagtaaacgt ctcttccaag gctctatttt
    15241 tcgctaactg ttcttctaac tcttgcgaac gtttagaaac atccaaggtg gccaaggtga
    15301 tataggcctt gtccttaaaa ttatctaaca attttttata ataggcttca ttcctcaaat
    15361 gaatctcttt tcgcttctca gtttttttca tcaactccga aaatgaatct aatagttcca
    15421 gtccaccata ttgaatctca agccctttgt ttcgtgctgt tcgaatagcc tgttttgttg
    15481 acttggaaag tttatcttct tcaaaatttt ccttgtatat tttcgcctga atacgaggtt
    15541 gaatggtgtc tcccatttcc tccgtttttc ctgaccacct tactcccatt tgttgcaaac
    15601 tatcaataat agccagattt tcaggaaatt ctgtcttttc ctgattgatt aaactttgag
    15661 ataggcaaat acttgggtca aaagtcacaa aaaccgctct cttactgcga gcataggact
    15721 taatagactg aatgacaaaa ttcaagagtt ctttatcccc ataatccaat ataggtcctc
    15781 ttgggatgta aaacatttta tagcctagcg gaagagttct aatcaaaata ctagctgtcg
    15841 ccagtaattt ttcttccctg taaacaccaa acttctcatg ttgccaatta gacttaactt
    15901 cctcccaagc actactttgt aatacattgg ctaattcatg ttctttgaca aactgatcat
    15961 attctaatgt gggaatgcca atttgataac ggtacatttc ctactctctt tcctccagta
    16021 ttttattact attctactac tttcgtttga aaagtctagt gaaaacatat tttattttag
    16081 ttctactccc cctatgctga agttcaaact aagtcagtct ctcttctaat ttgaaatcaa
    16141 ttggtagggt tgttaaaaaa acttccaatt gtttttccca gtagtaccac tcgtgagttc
    16201 cagcgctatg gctataggtc acatcaaaac ctagtttttt gagatttttc actgcgagat
    16261 tattggcttc gtacaagaaa tcctgttcgc cacaccacgc ccaaagtttg gtctttttat
    16321 ccgatttttt agccagactt tcaagagaat agggactagt tgtccagtct ttaatctctc
    16381 caaaaacacc tctccagtag gctggacttc ccagattttg actttcagga gaaaagtttt
    16441 gaaagctgag ggcacctgaa aagctagctg catgagaaaa acgatttgtc gcaagagcca
    16501 gtttgaagca gccgtagcct cccatagaaa gaccagcgat aaaggtcttt tcacgcttgc
    16561 tagtcatatt agggaagaag cgtttcagaa cctgtggcaa ttcctctgct agagccgtgt
    16621 agtagtcaaa accatactgg gtatcggtgt accaaccatt gctggtattg ggcataacaa
    16681 cgatgagatt agttcctcga agcaagcgtt ctacattggt ccgcttaagc caactattat
    16741 gatttccaga catcccgtgc aaaaggtaca agacgggaat atcttcacac tctggttctt
    16801 ccactcgatt ggcatcaggg tagaggacat tcacccccca ctccatatcc aatacttgtg
    16861 agtaatactc gattttcatt actgccatga ttttctcctt ctatttttct ataagaaaaa
    16921 gccgaaactc gactttctct ctgtttattt caacgattat tttgcttcca tgactactgg
    16981 taaaatagct ggacgacgct tggtttggtc aaagagatac ttggtcaaat tatctcgaac
    17041 cttcccttta agatctgccc agtcaaagtc atctccttga agatactctt ctaccgtttg
    17101 gttaatcaat tctgaacttt cacggagaat atcgcgactc ttcttgagat aaacaaatcc
    17161 gcgcgtatga acacgagccc tagccacaat tttcttctca cgacggttga ctgtaatagc
    17221 cacgatgaaa attccatcct ctgacaagac cttacggtca cgaagaacaa catttccaac
    17281 atcaccaatg gcattcccat caatcaagat atctcctgct gaaaccgatc cagctggaac
    17341 aaagtctcca ttctcgtaag ccatggtcgt ccccttttta ggaatgaaga tgtgttctgg
    17401 caacatccca actgccatgg cagccttagc gtgagcatcc aactcacgat actccccttg
    17461 gacagggaag aggtacttag gttgcaaaag attgatcatc agctgcaaat cacgcacatt
    17521 tccgtgccct gatacatgta aactttgggt aatcaatttg acaaccccac ctgcctgata
    17581 aatcatattt tccacacgcg caacaaaggc ttctttagca atagacggag ccgtagcaat
    17641 atagaccagg tccccatcct tgatttctac ataacgatgg cgaccaatcg acatcttacg
    17701 aagtccattg ataggttcac ccatacgacc tgtctcaaga ataatcaact catggtcttc
    17761 aaagcgagac atatctttag gcttaatcaa gagaatttcg ttggctaaag acaacttctt
    17821 aagacgaatc gctgtgcgga cgatattttc aatatcaaat cctgtcaaga cgatacgtcg
    17881 acctgtttta tccgcagcgt caaaaatctg ctgaatacga gaaagattac tggaaacagc
    17941 tgcaacgatg atacgacctt cccagtcagc aatagtttgg gtaatttcat ccctaacttc
    18001 actttcacta gccacctgaa tattgctgtc tgcattggcc gaatcactga ggagagccag
    18061 gacgccgtca cgaccaatct ctgccaaacg agcaaaatca gttgcataag attcactagc
    18121 cgtttggtca aatttgaagt cacctgtata aacgatgctt ccttccgatg tcttcaagac
    18181 aattcccaga ctctctggaa cggagtaagt cgtagggaag aaggaaacca ctgtcccacc
    18241 aaaatcaatc tccgtattct catcaatgac atggaaatca ttaaatttct taacggcatc
    18301 atttcctttg acaaagagct ttgccaactc aatggtcaac tcagacccaa atacaggaac
    18361 tttagcctct gccaagagat aaggtagagc accaatggca tccgcatgcc cgtgggtcaa
    18421 gaaaacccca gcaatacggt cgctattttc aaaaaggtaa tccatgtttg gaatcaccac
    18481 atcgacccct aattgttcat tttcaggata ttttaaccct acattcaaaa caaaaatgga
    18541 ctctccaatt tcagcaatgt acatattttt tccattctca cgcacaccac caagtgttgt
    18601 taaactgata ttactcattt ttcctccaaa atcttagttt atcttgatta tagggcaact
    18661 ctaccctctt attctaaaag ttctaatact ttcagccgaa tcttttccta ccattatacc
    18721 atttttttga tgattttcaa aatgaaggtc tgttttcaaa aaagagttga tttcccaact
    18781 ctttcctaac ttctactctt tttccatcaa aaaatcataa atttcttgca ccgtacccag
    18841 cgccatcatt tcttggtctt taacggtttg tttgagattt tggtaaattt gactttctcc
    18901 tatctcccgc tttggcgcct ctttattgac tgtcatcaca ccatctttta tcgtcacaaa
    18961 gcctagttct tcaaatactt gaatcatctt gaccagcaag atttgttgaa tattaagata
    19021 tgcagccaaa tctttcagct tgtagcgaat atcaaactct gggaactggt aaatagtctt
    19081 gtacaatttg gcaaactgat ctctagtccc ataacctgtc agataatagg ccttgtcaat
    19141 atcatttttg aaatagacag cagagaaatg ctgttcctga aaaatggtct tcagctgagt
    19201 aatatcctct ggaatgtttt ttacgacaat agcttcacta gccgcaagat ttggcagttc
    19261 tccaggaaaa tccaagactg gaacaccttc tggcaagact gcattttttc cacgaatgtt
    19321 aaaaagttga acaccttcca ctcgcgcatc caccatcatc aactggaggg cagtttggcc
    19381 attccattgg ttgacagaca atttaaccgc taactctaga ttcttggttt gagaaaactc
    19441 tgtcgcccat ctgccttgac caaaggctac cacttcaaaa ctcgccccac ccttggaaat
    19501 tttcagcttt agatgggcat tacctgcccc catagtacga gcactttcga cctgaaaatt
    19561 cttgatataa aaaataggtt tctgattatc cattccaaaa ggagctaaac gttcaaaact
    19621 tttgaccgtt tccaagctaa gtgcctccaa atccaactct tcatctaggt ttaacttatt
    19681 cttgccacca gcatctgcac ctttttcacg aacataatct tccaaaacct gagataaatc
    19741 tgagagttgc tcaacttcca gcgtcatacc cgctgcacct gcatgacctc caaaggcgat
    19801 gaagaggtct cgatggggat ccagagcttc aaaaatatcg accgcttcca cactacgagc
    19861 actgcccttg gcacgaccgt cttctatatt aagaacaatg actgtctgtc ccaattcttc
    19921 caataaacga ccagccacga ttcctagaac cccaggattc cagccttcct tggccaagac
    19981 ctgaaccttc ttctcaggat ccaccatggt cttggcttct tcatagatag actgaacgat
    20041 ttccttgcgc tcttcgtttt tctggtgaat cataagggca atctcatgcg cttcctcatc
    20101 atcaaatcca gtcaacaaat caatggcagg attgggatca tccaagcgac ccaaggcatt
    20161 caaacgagga gcaatctgga aaccaaccgt ttcttctgtt acttcgttgg cagcaatccc
    20221 agccatgtcc agcatttctt gcagaccaat gcgctgggta tgacccaaca tttccagacc
    20281 atattgaact aagatacgat tttcatccgt cagactcacc atatctgcaa tagttccaat
    20341 agcgaccaaa tcaagcaatt ccacttgcac ttcttctaac agggcacaag ccaacttgaa
    20401 agcaactcca caaccagcca aatatttaaa aggataatcc gcatctggat gttcaggatg
    20461 gacaatagca taagcatctg gcagggtttc aggcatggaa tgatggtctg tcacaatgac
    20521 atctactccc atagactgag ccaatgcaat agcctcatga ccagcaaccc cattgtccac
    20581 cgtcacaatc aaggaaattc cttcttgctc gataaagtat ttataaacac tagcattagg
    20641 gccatagcca tcggtaaaac gatttggcag gtaaactcgg cactccgcac caagttgttc
    20701 caaactttcc ttcacaatag aagccgaagt catgccatcc gcatcgtagt ctccataaac
    20761 gagaatattt tccctttctt caatagcctg acgaatccgc tccactgcct tgtccatatc
    20821 atggagcaga taagcatcat gtaagtcctc caaggaaggt tctaaaaact tcttcagact
    20881 ttcttggtcc tgaatccctc tctcaaacaa taaccgagcc acctcaggac ccagtccagc
    20941 cttcttggct atctttgtaa aatccgcatc ttctacctgc agggcaaact gccattcata
    21001 agtaggtgtt atcaaaaaga catccactcc ttctaagaat tctattgctt cattataaca
    21061 tgatttagac gttttctcta tccagattgc ttttttataa catttcatag tatattgaaa
    21121 ctagaatagt acacctctac ttctaaaata ttgttagaaa tcgatttgac tgtcccgatc
    21181 gatttttcct gttcttattt cactatagtg aattttttca gatatggttt gacaagaaca
    21241 ttcttttatt gcagaattgt gttataaaat ctaacataaa ggagttctct catggcttta
    21301 gtagaattta aaaacgtcga aaaatattac ggagactacc acgcactccg caacatcaat
    21361 ctccgttttg aaaaaggaca agttgttgtc ctgcttggac cttctggctc tgggaagtcc
    21421 actcttatcc gtacgatcaa tggtttagag gctgttgaca aaggaagtct cctagtcaat
    21481 gggcaccaag ttgctggtgc cagccagaaa gatttggtac ctcttcgcaa ggaagtcggc
    21541 atggtttttc aacattttaa cctttatcca cacaaaacag tgttagaaaa cgtgacactt
    21601 gcacccatta aagttctagg aattgataaa aaagaagctg aaaaaaccgc caaaaaatat
    21661 ctggaatttg taaatatgtg ggacaagaaa gattcctatc ccgccatgct atctggtgga
    21721 caaaaacagc ggatcgccat cgctcgtggt cttgctatgc atccggaact cctcctcttt
    21781 gatgaaccaa catctgctct tgatcctgag actatcggag atgttctagc agttatgcag
    21841 aaactggcgc gtgatgggat gaacatgatc atcgttaccc acgaaatggg ctttgctcga
    21901 gaggttgcgg accgcattat ctttatggcc gacggagaag ttttagaggt tgcggaccgc
    21961 attatcttta tggccgacgg agaagtttta gtagatacga cagatgtcga taactttttt
    22021 gacaatccaa gcgaacctcg tgcccaacaa ttcctcagca aaattatcaa ccacgaaagt
    22081 gacaaagtca aataaggagg cgcctatgaa aaaaaattct ttttatcagc attattgatt
    22141 agccttttcg gccttgctgc tgccaaacca gtccaggctg atacaagtat cgcagacatt
    22201 caaaaaagag gcgaactggt tgtcggtgtc aaacaagacg ttcccaattt tggttacaaa
    22261 gatcccaaga ccggtactta ttctggtatc gaaaccgact tggccaagat ggtagctgat
    22321 gaactcaagg tcaagattcg ctatgtgccg gttacagcac aaacccgcgg ccccctccta
    22381 gacaatgaac agggcgatat ggatatcgcg acctttacca tcacggacga acgcaaaaaa
    22441 ctctacaact ttaccagtcc ctactacaca gacgcttctg gatttttggt caataaatct
    22501 gccaaaatca aaaagattga ggacctaaac ggcaaaacca tcggagtcgc ccaaggttct
    22561 atcacccaac gcctgattac tgaactgggt aaaaagaaag gtctgaagtt taaattcgtc
    22621 gaacttggtt cctacccaga attgattact tcccttcacg ctcatcgtat cgatgccttt
    22681 tccgttgacc gctctattct atctggctac actagtaaac ggacagcact actagatgat
    22741 agtttcaagc catctgacta cggtattgtt accaagaaat caaatacaga gttcaacgac
    22801 tatcttgata acttggttac taaatggagc aaggatggta gtttgcagaa actttatgat
    22861 cgttacaagc tcaaaccatc tagccatact gcagattaag gaggacaccc catgacagat
    22921 ttatcatctt ggacagccta ttttcaggat tttggacaat ttttcaatgg tttcctcttc
    22981 acccttgccc tagcgattgg atcctttatc ctcgccatgg tcttaggaat cttctttggt
    23041 gccatgtcaa ccagtaaacg tccaatttta cgcattttag ctcgcatctt tgtggaattt
    23101 taccaaaaca ctcccctctt ggtgcagttt gttattgttt tttatggcct acctcttatc
    23161 agtgaccata ctatcatgat tccgatttat tggacagctg ttctctgcgt gggactctat
    23221 cacggcgctt atatcgctga ggttattcgt tcagggattc agtctattcc tagtggtcag
    23281 atggaggccg ccttatcgca aggttttacc tatatcagtg ccatgcgctt gattatcttg
    23341 cctcagacct tccgcatcat tctccctcca ttgaccaacc aaattgttaa cctcatcaag
    23401 aacacctcta ctgtagctat catctctgga gtagacttga tgtttgtgac taagtcttgg
    23461 tcggctctca acggaaacta tatcccagcc tttttaggtg ctgctcttct ctactttgcc
    23521 ctatgcttcc ctgttgccca gtttggtcgc aagatggagc aagccaacaa aaaagcctat
    23581 tcactttagg aggttactat ggaatctatt ttagaagttt taaccccaga taacctagtc
    23641 tttatcttta aaggatttgg cttgaccctc tatatttctc tgattgccat catcctctct
    23701 actatcatcg gtacggtgct agctgtcatg agaaatggca aaaattctgt cttgcgaatc
    23761 atctccagta tttatatcga gtttgtgcgc aacgttccca accttctctg gatttttact
    23821 atctttttgg tgttcaaaat gaaatccaca ccagcaggta ttacagcctt tactctcttt
    23881 acatcagcag ccttggctga gattattcga ggcggtctca atgccgtaga caagggacaa
    23941 tacgaagcag gaatgtcaca aggcttcacc tcagcccaaa tcctctacta catcattctc
    24001 ccacaagcca tccgcaaaat gctaccagcc atcatttctc agtttgttac cgtgattaag
    24061 gataccagtc tcctctactc tgttatcgcc ctacaagaac tctttggagc cagccaaatt
    24121 ctcatgggcc gttatttcga accagagcag gtcttcagtc tttacatcct gattgccctc
    24181 atctacttca gctttaacct agcaatttct agcctgtctc atatgctagc caaacgttgg
    24241 caacaagccg cagaataata ctcttcgaaa atctcttcaa accacgtcag cttcaccttg
    24301 ccgtatatat gttactgact tcgtcagttc tatccacaac ctcaaaacgg tgttttgagc
    24361 agcctgcggg ctagcttcct agtttgctct ttgattttca ttgagtataa acagccactc
    24421 tccaattcaa ttggagagtt ttttgatgag agtagatatt tatagacctc aatttgacac
    24481 catacatttt ctatgataaa atgtaacaaa ttcatttaca acaaatcgaa atctaaatga
    24541 aatggaattt tctatgaaat cagtcaaagg actactcttt atcatagcta gttttatctt
    24601 gactcttttg acttggatga acacttctcc ccaattcatg attccaggac tagctttaac
    24661 aagcctatct ctgactttta tcctagccac tcgtctccca ctactagaaa gctggtttca
    24721 cggtttggag aaggtctaca ccgtccacaa attcacagcc tttctctcca tcatcctact
    24781 aatctttcat aactttagta tgggcggttt gtggggctct cgcttagctg ctcagtttgg
    24841 caatcttgcc atctatatct ttgccagcat catccttgtc gcctatttag gcaaatacat
    24901 ccaatacgaa gcttggcgat ggattcaccg cttggtttac ctagcctata ttttaggact
    24961 ctttcacatc tacatgataa tgggcaatcg tctccttaca tttaatcttc taagttttct
    25021 tgttggtagc tatgcccttt taggcttact agctggtttt tatatcattt ttctatatca
    25081 aaagatttcc ttcccctatc tagggaaaat tacccatctc aaacgcttaa atcacgatac
    25141 tagagaaatt caaatccatc ttagcagacc tttcaactat caatcaggac aatttgcctt
    25201 tctaaagatt ttccaagaag gctttgaaag tgctccgcat cccttttcta tctcaggagg
    25261 tcatggtcaa actctttact ttactgttaa aaattcaggc gaccatacca ataatatcta
    25321 tgataatctt caagccggca gcaaagtaac cctagacaga gcttacggac acatgatcat
    25381 agaagaagga cgagaaaatc aggtttggat tgctggaggt attgggatca cccccttcat
    25441 ctcttacatc cgtgaacatc ctattttaga taaacaggtt cacttctact atagcttccg
    25501 tggagatgaa aatgcagtct acctagattt actccgtaac tatgctcaga aaaatcctaa
    25561 ttttgaactc catctaatcg acagtacgaa agacggctat cttaattttg aacaaaaaga
    25621 agtgcccgaa catgcaaccg tctatatgtg tggtcctatt tctatgatga aggcacttgc
    25681 caaacagatt aagaaacaaa atccaaaaac agagcttatt tacgaaggat tcaagttcaa
    25741 ataagtaatc atactctcct gggatttccc aggagagttt tttatagcca aatgaaataa
    25801 gaccggaacg atggaatttt ggcattcaaa tcaattgata agaatatttt atagtggagt
    25861 gaaataggat acgaacaaat tgattaggaa aatcaaatga atttatagaa atcttttagc
    25921 agttatgttg tcctattcta gtttcaaaac gctatagaag cagcattgta ctagtctaga
    25981 ttcagtttac tatactaaaa cgagtagctt gaaatcaaaa aacccaccct cacaggcagg
    26041 ttttatctgt attattcagc tagattatgc tttaccttct gaaccgaata cgtcgatacg
    26101 ttcttcaacc gatgcttgga tagcttttac accgtcagcc aagaatttac gtgggtcgaa
    26161 gagttttttc ttgtcgtatt ctgcttcgtt tgcttcgtag tcacgagcaa atttacgagt
    26221 tgcgttagcg aatgcgattt ggcattctgt gttaacgtta actttggcaa caccaagttt
    26281 gatagctgct tggatttgct catcaggaat acctgatcca ccgtgcaata cgattgggaa
    26341 tcctggaaga gcttctgtca atttttgcaa gtggtcaagg tcaagacctt cccagtttac
    26401 tgggtaaggg ccgtggatgt taccgatacc agctgccaag aagtcgatac cagtttcaac
    26461 cattgcttta gcgtcttcga ttggagccaa ttcaccttta ccgatgattc cgtcttcttc
    26521 accaccgata gtaccaactt cagcttctac tgagatacct ttagcgtgtg ctttttcaac
    26581 aacttcttta gccaatttaa ggttttcttc aactggaagg tgtgaaccgt caaacatgat
    26641 tgaagtataa ccaacttcga tacactcaag tgcatcttcg tagtgaccgt ggtcaaggtg
    26701 gatagctact ggtacagtga tacccattga ttcaacaagg ttagcgatca agttgcgagc
    26761 aactttgtaa ccacccatgt atttagcagc acccattgaa gtttggatca aaactggagc
    26821 ttttttagct tctgctgcgc gcaagatagc ttgagtccac tcaaggttgt ttgtgttaaa
    26881 tccaccaact gcataaccgt tgtcacgggc tgcttggaca aatttttctg ctgaaacgat
    26941 tgccatttta tcaggcctcc tgtatatttt tatgggtcat cccatttaca ttgttcattt
    27001 tatcactttt tgccaaaaaa atctagtttt tcccgcagtt tcgattgatt ttcttctaac
    27061 tccatctatg taaacccttt ctctccctag tcttgggcga cttttggaaa agctataaag
    27121 aaggttaaac gattctcctc catctcgaaa cgataagcta atttttcatg ttctaataga
    27181 ctcttaacca caaagagccc cataccagac cccttgacct tgcgactggc attgtcagaa
    27241 aaagactggg ctagtttttc ttgttcctct gagctacagc tattttcgat aaaaagttct
    27301 ccttctcttt ctccaattcg aactaagcca cctggaacag agtgcttaat ggcattgctg
    27361 atgagattag aaagaatcaa cttcataact gatgggttta gataagcctg ctgatgggtc
    27421 aaactattgt ctatctggag ctctctttcc ttggctagca aggcataatc tttgaccaga
    27481 ttttgcgtca tctggaggag gtcaattgtt tccctatcat ctcgcaattc ctgcacagaa
    27541 gagagggaaa gtatctgcag aacatggtga ttgagttcat ccacaatccc caaggcaact
    27601 cccagatact ggtctctatc cttataacga ccgatattct ctctcatatt ttcgattagg
    27661 attttcaaac tagccagcgg tgttttcaat tcatgagaag ctcctcgtag gaattcgacc
    27721 ttcatcttct ccagctggag aatggcttca ttcttttcat gcaagtccgc aataacagtc
    27781 aagagatgct ggtagaggct attgatttgt tccttgagat tacctatctc atccttagaa
    27841 tccacgcgca atcgcacttg ggaatccagg tccatcatcc gacgggtcac ccgcttgatt
    27901 tccaaaatcg gtgcaacaat agtccgggcg tagatgtagg ccaccaagag ggaaatcaga
    27961 aaggaggcca gcaaggtata gggaagaaac tggagactga tttgctccgc ttccttttgt
    28021 aaatccatgg aagctagaaa ctggagaatc atagtaccac cgtcttgcgt tttcacctcg
    28081 cgctcctcaa taaagagaga ggttgtctgg cggtctgtgt ccagaggaag actgtccttg
    28141 acttctaact tgtcctcggt catctcacct ttgacggtcc ccttgatatc actagtctgg
    28201 gaatacaagt ctaacacttg ctcgatactc tgcctatctt tcccttctag ggactgggca
    28261 atggctgttg ccttttgacc aatggtttcc tgacgatgac tcagataagt cgaaggaaaa
    28321 agaaaataaa tagctaaatg aaggcagata accagaacac taaatatcga gaaggtatag
    28381 ataaatatct ttgcaaataa acctgttcgt ttcattttcg ctccaattta taaccaacat
    28441 tgcgcacagt gaggatacaa tccaagtcta gctttttccg caattccttg atataaacat
    28501 caataacacg gtcaaaggga acctcatctg tcgctttcca gacggcatcg ataatctgag
    28561 accgagtcaa ggcccggcct tcatttttca ctagatagtc cagaatttcc aactctttgg
    28621 cattgatagg cacttcttga cctgcgaggc ttgcactgta gctttcaaag tccaccttgg
    28681 tatccttgta agaaaagatt cgtcctgtat cgtagtagcg cttgaaaatc gcgtccaccc
    28741 tcacttttaa gagggagaga gagaaaggtt tttccagata gccatctgcc aaagaggcaa
    28801 aggcactcat cttgtattcc tcatcctgaa aagctgtcaa catcaagaca ggaacctgac
    28861 tggttttacg aatctcagct aggacttcta agccgttaag cttgggcatc tggatatcca
    28921 gtaaaaccag ggccacctca tagctagaaa attgctccag agcttcctga ccgtccgctg
    28981 cctcaatagt ttcatagcca caatccgtca aataatcact gaccccctca cggatcatct
    29041 cttcatcttc tacaattaaa attttcatac tttaactgct ctctattttt tatttttctt
    29101 agaataaata cctactctat tttctattat agtctcttgc tggccttttg tctgtaagca
    29161 actgatcact agataaaacg ttgtgaaatt cctttctcat aaattccata actttagtat
    29221 attatattta agcactaaag tacaaagaaa gcaactgaaa gcaatgattt tcaccactgc
    29281 tttcagattt attttgaatt gttaaatagc tattcctatc cactattctt gaatagaaac
    29341 acaagatgca atctttattc cagactcatt ttttcaaatt tattcaccat ccagcaagag
    29401 ctcttttggt tgttttctaa ggagattgct tgaagcaagc gccataacga gaaccactag
    29461 aaccaaggca aggacaaaaa tgatgataaa gtctgatgtc tgaatggaaa tgtctaggct
    29521 cgacaaggtc ttgctaaagc catctacttc tgcaccgcca ccaaggttag aggcttgagc
    29581 cgccttacta gcctgtttgg caacacctga agtcacattg gcaaggacag tgtttccaat
    29641 tgcacgggca gtgtaattag ctaggaagta agcagaaact agagcaggga tagcaatcaa
    29701 gatagattcg gtgatgaatt gacccaagat acttgcctgc ttgaggccga tagagaggag
    29761 aattcccact tccttgcgac gggcgttgat ccaaaggctg agcaagaggg caaggaggag
    29821 aactgagaag ctcaagctac cccagaagag gaggttggcc atcttgtaca taccagagat
    29881 agattgctca agagctgggt agttagagga gctcttgacg agtgtgtagc tcttccagtt
    29941 gataccactg atgccattca actctttcat aacatcatcc aagttcttgt ctgctgttac
    30001 aaagaaggtt gcgtccccat aaatggctgt gtcttctgtg tatccataaa gttttgcagc
    30061 agtgtgaatg tctgtaatag ctgtgttttc gtaaagttct tgtgagtagg ttactgctga
    30121 cttattatga ccatcaaaga gtcccttgat tgtcacttca actgtttcct tggctccttt
    30181 ttcattatct gcatcgtaga tattagagtc cagtttaacc ttgtccccta ctttccagcc
    30241 gtgtttggct gccaagtcct tgtgcaagag gattttatcc ttgtcgtcgt tggttaagtg
    30301 ctctccttcg actagtttat aagaaccaga gacaaacttg tcttctttag aggagtcatt
    30361 gacacctgta atcatcaagc tacttccaaa acgtttggca cgatcagcag tgagattctt
    30421 cttggtttct ggcgtttcaa tcaggtcata tccagtcaaa tctccgatag cgttgatacg
    30481 tttgacataa gactcaatgg ccttgttttc ggtgattttt ttgatgtctt cacccttgat
    30541 attcccagca ccgcgaggcg ttccttggtt gacgcgacga ttgatttgca tggagaagct
    30601 attggtgata tttttaaagg tctcctgaga agccttggca gtagctccct tgattgacaa
    30661 gccgaccaaa ctcaagctcg ccatgaggag aataatcagg aagatgacaa tcgatttgaa
    30721 aaacttcctt gtaacatagg caaatgcgtt gtgtaacata gattcccttt ctagattttg
    30781 ttttaatcat tctattaaag taagctcaaa ttatttacta gtattgcgcg tttcagtcag
    30841 tttcttatcc tttaattcaa gtgtaatatc tgacgcttgt gccacttctt tactgtgagt
    30901 tacgacaatc acacatttac ctgttttctg ggcaagtgat ttgagtagtt cgacaatatc
    30961 tccagcagtt ttaggatcca gatttcctgt tggctcatca gctagaataa ctggagcttc
    31021 tgagaccaaa ctgcgagcaa tggcaacacg ttgctgttga ccacctgata actggagaac
    31081 attccgcttg atctggcttt catccaaacc aagctcaaga agtgtattct tgcttgcctt
    31141 tttgttgacc aatcggatat tttccagcgg agaaagataa tctatcaagt tataattttg
    31201 aaagaccagg gaaatatggt gcatgcgatg gtaagaatag cccttcttac gaatatcctc
    31261 tccttgaaaa aggatagaac cttcaacagg actatctaga ccagcaagta gggacaagag
    31321 tgtggatttt cctgctcctg actccccaat aatactgtaa aattttccgg gttcaaaatt
    31381 ataattgatc tgatatagga ctgcttcagc agtattctta taacggtagg taacatcttg
    31441 taattgtaat aaagtcatga tttctccttc ttaactaata gatgataaaa tttctttcgg
    31501 tgattttcta aataagaata ggaaacaaag ggctacagat aagcaactaa gcagaactag
    31561 aaaaacatag gattctgcaa aagataagat gctagttgat aaactgcttg ctttggctag
    31621 tgtatcttgt aagcttgcct gatctccact tgctagtaga gtttggagta ggtaagttgt
    31681 gattccgttt cctgcaacaa atgctggaag caaagctcca agagatacca aaactacctc
    31741 taaacagaat tgtaggaaaa tcgagctctt gccttttcca agtgcaagta aaatccccac
    31801 ttcatagacc cgttctctca accagagaga caaaaccaga attaaggctc cagctcctgc
    31861 tatcaacatc ccataaagga agatggtcag gaaggtttgg aaagttgcaa ctgagtcttt
    31921 gatttgttca aaagccttgt tttccttttc gacttggtag ccttgatttt ccaaggccaa
    31981 gttttctacc tgcttcatga gtccgtccat ttccttagga ttttctacat agaagcgtgc
    32041 tgcactgact tgagcttcac tattgcccaa aagggtttgg ctactttcat agtctgtaaa
    32101 gacttgattt tcactgaagt cagaagacaa gcctgtgaat ttctcttgtt ttttaccaga
    32161 aaagatgccg ataatctcaa actctactgt ttgtcctttt ccagattcag actgaccagc
    32221 atccaagcca atcttgtcat gaagtgaaag accgttcttc ttagccaatt cttcgtggat
    32281 aaggattttc ttggaattcc ctttttgaag gtgtcgccct tcttttagat tgaaagccga
    32341 actggtaaag gttacatcct tggatgaatc ctcaagagcc gttaagctaa ccaagttatt
    32401 gtctgcagct gataaatcat cacgctccac gctctgctcg ccagtcactg cttccttgtc
    32461 ttttagtttt gcgaccgtct cgagttcagg agagacattt tccagcccct taatcttgct
    32521 tacagatgct aggtctgaca acttgaatgt ctgaccattc tctatcttct taatagaaaa
    32581 agatgtattg agtgatttat aaagattgct ttctactgtt ttgttggact tcatcagagt
    32641 caaacaggct gaaattccgg ccaataagac caataaaatc agaaataaaa taaaacttct
    32701 cagtcgcttt ctgctgacat aagcccaaga tctttggatt ggattcattt gtcacctcca
    32761 tatttgtaag actattataa aacccaaata tgaaatgttt atgaaatacg aaaaaaaaat
    32821 atcgagtagg ggataatctc tagcccctct cataccaccg tacgtgccgt tcggcatacg
    32881 gcggttcaac taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt
    32941 ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact
    33001 atagtagatt gaaactagaa tagtacacct ctacttctaa aatattgtta gaaatcgatt
    33061 tgactgtcct gattgattcg tcctactctt atttcatttt actataattg atagtggtcg
    33121 ccccagccag ataccttatc tgctatccat ttaggaaccc ctaacttaag caatccccat
    33181 aatcgtctcg atttcttctt ccattgcttc cagataatca ctcgtaggcg agtacgcaag
    33241 cgctcatcta tgctagtgac tatacttttc atatttataa ttcattcctt tcgtttcact
    33301 caaggcacaa cacagaatga aaaagtgttg tgctctttat tttgttttat aataatagtt
    33361 agaaagccta tcactactac aaatcacggg gaggtgaata agtgagtggt acagccacta
    33421 cctcgcatat tttgtcacat catttaacgg tacataataa gttgtaccat ctgaataagt
    33481 tgctacaata tcatttgcat gctctccttc acctttagca aaggttggag ctcctactgg
    33541 ataattttta tttgcctctt tcaatttttc aataatggca tttttttctg tatcttttat
    33601 attatcagga tttttcacta agattttgtc tggatatgtc ggtttagcag aaacaatttt
    33661 tactgttatt tcttttttat tcgaagcact tgtccagttt ccagcattat ctttagcatt
    33721 taattttaca gtaattcctg aactaagaac ttcagtagca ggttgattat caacattatt
    33781 caactttaat ttcaaaagag ctgttgcatc agacgtttta tcaatcgttg tatataatga
    33841 taaattgtta ttataaccag tttcttcata tttagctgtt tgtgagctac ttgaaacaga
    33901 actgaaatta tgcccactac ctccctgatt atcttcaatg cttacgtcta aatgaacttc
    33961 cccactatta tttggcttag caacaactgt tatagtaaaa taacataaaa tttgcataaa
    34021 tagattaggg aaatcaaagc aacttctagg aatgttttat actcttcgaa aatcaaattc
    34081 aaaccacgtc agcttcacct tgacgtactc aagtacagcc tgcggctagc ttcctagttt
    34141 gcactttgat tttcattgag tattagcagt cacagtgtac tttcccagca tcaagtcact
    34201 ataactctgc acataaaaat ggagaagatg gccatcctct tctccaaata ttaacggctc
    34261 tataatattt gtagtgggta aatcccctat ggatattatg gagcctattt ttgtgtagaa
    34321 aaaaagtccc ataagatcta taatgaaaag cgatcaaaca actcattaga aagattcata
    34381 tggaacaatt acattttatc acaaaactac tcgatatcaa agacacaaat atccaaatta
    34441 tagatgtcgt caatagggat tcacacaaag aaatcatcgc caaactggac tacgacgcac
    34501 catcttgccc tgagtgcgga aaccaattga agaaatatga ctttcaaaaa ccttctaaaa
    34561 ttccttatct tgaaacgact ggtatgccta ctagaattct ccttagaaaa cgccgtttca
    34621 agtgctatca ctgttcaaaa atgatggtcg ctgaaacttc tatcgtcaag aagaatcacc
    34681 aaatccctcg tatcatcaac caaaaaattg cgcaaaagtt gattgagaag atttctatga
    34741 ccgatattgc tcatcagctg gccatttcaa cttcaactgt tattcgtaag ctcaatgatt
    34801 ttcactttaa acatgatttt tcttgtcttc ctgagattat gtcttgggat gagtatgctt
    34861 ttacaaaggg aaagatgagc ttcattgcgc aagattttaa caatctcaat atcatcactg
    34921 ttcttgaggg tagaacacaa gctatcattc gaaatcactt tcttcactac gatagagctg
    34981 tccgatgtcg cgtcaaaatc attactatgg atatgtttag cccttactat gacttggcta
    35041 aacagcttcg ctttcaaatt tctaggctca ggctgaaaca gtctcccaga ctgtttcact
    35101 cccgaatgct aaaatcgttc ttgatcgctt tcacattgta caacatctta gccgtgctat
    35161 gagtcgtgtg cgtgttcaaa tcatgaatca gtttca
//
LOCUS       DBERCW010000021        35002 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.021, whole genome shotgun sequence.
ACCESSION   DBERCW010000021 DBERCW010000000
VERSION     DBERCW010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.021"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(381..1361)
                     /locus_tag="ACL72M_001243"
     CDS             complement(381..1361)
                     /locus_tag="ACL72M_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGS0716368.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1678..3693)
                     /gene="recG"
                     /locus_tag="ACL72M_001244"
     CDS             complement(1678..3693)
                     /gene="recG"
                     /locus_tag="ACL72M_001244"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGS0716369.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLI
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3712..4815)
                     /gene="alr"
                     /locus_tag="ACL72M_001245"
     CDS             complement(3712..4815)
                     /gene="alr"
                     /locus_tag="ACL72M_001245"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGS0716370.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4805..5167)
                     /gene="acpS"
                     /locus_tag="ACL72M_001246"
     CDS             complement(4805..5167)
                     /gene="acpS"
                     /locus_tag="ACL72M_001246"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGS0716371.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(5212..6243)
                     /locus_tag="ACL72M_001247"
     CDS             complement(5212..6243)
                     /locus_tag="ACL72M_001247"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS0716372.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6245..7276)
                     /locus_tag="ACL72M_001248"
     CDS             complement(6245..7276)
                     /locus_tag="ACL72M_001248"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS0716373.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7357..9870)
                     /gene="secA"
                     /locus_tag="ACL72M_001249"
     CDS             complement(7357..9870)
                     /gene="secA"
                     /locus_tag="ACL72M_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGS0716374.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10016..10303)
                     /locus_tag="ACL72M_001250"
     CDS             complement(10016..10303)
                     /locus_tag="ACL72M_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716375.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10331..10963)
                     /locus_tag="ACL72M_001251"
     CDS             complement(10331..10963)
                     /locus_tag="ACL72M_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0716376.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10967..11608)
                     /locus_tag="ACL72M_001252"
     CDS             complement(10967..11608)
                     /locus_tag="ACL72M_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716377.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLVFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11601..12392)
                     /locus_tag="ACL72M_001253"
     CDS             complement(11601..12392)
                     /locus_tag="ACL72M_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716378.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12414..12806)
                     /locus_tag="ACL72M_001254"
     CDS             complement(12414..12806)
                     /locus_tag="ACL72M_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716379.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            13133..13984
                     /locus_tag="ACL72M_001255"
                     /note="rgg1518"
     CDS             13133..13984
                     /locus_tag="ACL72M_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator
                     Rgg1518"
                     /protein_id="HGS0716380.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            complement(14216..14566)
                     /locus_tag="ACL72M_001256"
     CDS             complement(14216..14566)
                     /locus_tag="ACL72M_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716381.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(14706..15041)
                     /locus_tag="ACL72M_001257"
     CDS             complement(14706..15041)
                     /locus_tag="ACL72M_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716382.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(15129..16439)
                     /gene="der"
                     /locus_tag="ACL72M_001258"
     CDS             complement(15129..16439)
                     /gene="der"
                     /locus_tag="ACL72M_001258"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGS0716383.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(16453..17166)
                     /locus_tag="ACL72M_001259"
     CDS             complement(16453..17166)
                     /locus_tag="ACL72M_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGS0716384.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(17163..18059)
                     /gene="dnaI"
                     /locus_tag="ACL72M_001260"
     CDS             complement(17163..18059)
                     /gene="dnaI"
                     /locus_tag="ACL72M_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGS0716385.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(18060..19229)
                     /locus_tag="ACL72M_001261"
     CDS             complement(18060..19229)
                     /locus_tag="ACL72M_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS0716386.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(19230..19703)
                     /gene="nrdR"
                     /locus_tag="ACL72M_001262"
     CDS             complement(19230..19703)
                     /gene="nrdR"
                     /locus_tag="ACL72M_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGS0716387.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            19843..20208
                     /locus_tag="ACL72M_001263"
     CDS             19843..20208
                     /locus_tag="ACL72M_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0716388.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            20213..20908
                     /locus_tag="ACL72M_001264"
     CDS             20213..20908
                     /locus_tag="ACL72M_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716389.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            20925..21692
                     /locus_tag="ACL72M_001265"
     CDS             20925..21692
                     /locus_tag="ACL72M_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716390.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(22045..23244)
                     /locus_tag="ACL72M_001266"
     CDS             complement(22045..23244)
                     /locus_tag="ACL72M_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716391.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(23241..24134)
                     /locus_tag="ACL72M_001267"
     CDS             complement(23241..24134)
                     /locus_tag="ACL72M_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716392.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            24257..24448
                     /locus_tag="ACL72M_001268"
     CDS             24257..24448
                     /locus_tag="ACL72M_001268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716393.1"
                     /translation="MKIKEQTRKLAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYTYGKAKLTWFEEIFEEY"
     gene            24841..25029
                     /locus_tag="ACL72M_001269"
                     /pseudo
     CDS             24841..25029
                     /locus_tag="ACL72M_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            25444..26061
                     /locus_tag="ACL72M_001270"
     CDS             25444..26061
                     /locus_tag="ACL72M_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGS0716394.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(26381..27268)
                     /gene="scrK"
                     /locus_tag="ACL72M_001271"
     CDS             complement(26381..27268)
                     /gene="scrK"
                     /locus_tag="ACL72M_001271"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGS0716395.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(27417..29300)
                     /locus_tag="ACL72M_001272"
     CDS             complement(27417..29300)
                     /locus_tag="ACL72M_001272"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGS0716396.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            29677..31131
                     /locus_tag="ACL72M_001273"
     CDS             29677..31131
                     /locus_tag="ACL72M_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS0716397.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31112..32077
                     /locus_tag="ACL72M_001274"
     CDS             31112..32077
                     /locus_tag="ACL72M_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0716398.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKPAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(32112..33386)
                     /locus_tag="ACL72M_001275"
     CDS             complement(32112..33386)
                     /locus_tag="ACL72M_001275"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGS0716399.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(33386..34558)
                     /locus_tag="ACL72M_001276"
     CDS             complement(33386..34558)
                     /locus_tag="ACL72M_001276"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGS0716400.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(34689..34937)
                     /locus_tag="ACL72M_001277"
     CDS             complement(34689..34937)
                     /locus_tag="ACL72M_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716401.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPISQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT        10348 a         7755 c         6523 g        10376 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttaaaga gatttttgaa aagtattaac
       61 acctacagac aagcctgacg atagcaagaa ctaccctact cgataggtat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 ataatagatt gaaactagaa tagtacacat ttgcttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gatcgttttg tcctattctt gtttcatttt actatatttc catgataaaa
      301 cgcatagtat caagtttttt taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atgcgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattaatg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aagtgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga agggtaaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaaagagca tttcgctctc tcttctgttt atactagttt tttgcttcct tcttttggaa
     1561 agtggtttgg taatttactt taatcgttac tgtcatatga gagtcctcgt ttctttttga
     1621 tgactttagt ataagagcca aacctaaaaa ctagcttaag ttttccttag agaaagctta
     1681 atccagatgt tctttctttt ccagatgaag ggcaatcatg cgccactctg gatcttcttg
     1741 ccaagcttct atagaactaa tgtagctagc aacctttctt gcttcttcta aaatcggaaa
     1801 atcttcgata atatcagcca cttggaactc tggaagtcct gactgtctgg ttccaaaaat
     1861 ctcaccagaa ccacgcattt tcaaatcttc ctccgcaagg acaaatccat tggtcgtttc
     1921 tgtcatgata cgcatgcggt ctttcccaga atccgtcttg ggattagcaa cgagaacagc
     1981 gtaggactgc ttgtcccccc gaccgacacg acctctaagc tggtgaagtt gactgagacc
     2041 gaagcgatcg gcatccatga taatcatgac agtcgcattg ggaacgttga ccccaacctc
     2101 aataaccgtc gtcgaaacca gaatatccgt ctttctctcc ttgaaatcct gcatgatctg
     2161 gtctttttcg tcactcttca tcctaccatg tagaagagcc acctctgcct tgcctgcaaa
     2221 atgagtcgtc aactcctctg ataaggcaat ggcatttttc aaatctagag cttctgattc
     2281 ttcaatcaaa ggagagatga cataggcttg ggaacctttt tgaatttccc cctctaacca
     2341 agtcaagacc tgaggtagtt gctcatgttt gatccagcgc gtcacaatag gcttccgacc
     2401 tgctggcatc tggtcgataa tggaaacatc catatctcca aaggctgtga tggcaagcgt
     2461 ccgtggaatg ggagtcgccg tcatcatgag gacatctgga ttgtcacctt tttcccgtaa
     2521 aatacgcctt tgccctacac caaaacggtg ctgctcatcg ataataatca aagcaagacg
     2581 agcatactcc accccatctt gtatcagagc gtgagttccg ataatcaaat cagcctcacc
     2641 cttggcaatg gtctccaaga cctctctctt ttctgcagct ttcaaggaac ctatcaagag
     2701 agccagtttc aaattgggaa aaaggttctg taaactctca aagtgttgct ctgcgaggat
     2761 ttctgttggt accattaggg cagcctgata acctgctgtc actgccgcaa acatggccaa
     2821 gccagcgact accgtttttc cactccccac atccccttgt aggagacgat tcatgtggtg
     2881 gtcggacttc atatcagtta aaatttcctg caaactcttt tcctgagctt gggtcagggc
     2941 aaaaggaaga cttactttaa ctgctgtcac tttttcctga gaccaattca gaaccagacc
     3001 acttccctga actctatttt cagacttgag catctgcagc tgcatttgga aataaaagag
     3061 ttcctcaaac tttatacggc gaagagcctg cttgtattct gccaaatcct ttggaaaatg
     3121 catagctcgg actgcctgac aacgggacat gagtttgtat ttgtctagta aagactgggg
     3181 cagattttct tctatcaaga ggtccagtcc ctgatcaaaa gccgtcttga tgaccttgac
     3241 cagactggcc tgactgattc cctgagccag acgatagaca ggctggaggt catcttctac
     3301 ctgagccaga accttcatcc cagtcagact agccttagcg cggtcccatt ttccaaagac
     3361 agcaagggtt gctcccaact ctattttatc agccagatag ggctggttaa agaaattcac
     3421 cgcaaaaacg acctctccct gcttgagact aaaacgcagg cgattgcgct tgaaaccata
     3481 atactggaca ctagcaggag tcactacctg accagaaaga actgccttct caccgtcttc
     3541 cagctccagc acctgcttgg ttttgaagtc ttcataacgg aaaggaaagt agagcaagag
     3601 atcttgcaag ttttcaattc ctagtttggc gtatttttct gctgactttg gtcccacacc
     3661 aggcaagaca tgcaagggtt gatgtagatt catgctccac tcctttcttt tctaataata
     3721 ttctctcgga atacggtcgc tgaggaggca aaccacctca tagttaatgg ttacgcggta
     3781 ggtcgctacc tgagttgcag tgatttcctt atccccattg gagccaatca aggttacctt
     3841 ggttcctagc ggataaagct taggcaatcg aatagtgatt tggtccatcg aaaccctgcc
     3901 gacaattggg caagcttggc catctaccaa gacagagaaa ttttgcatgt ctcttgtcca
     3961 tccatctgca tacccgattg gcacggtcgc gatgacttgc tcgctatccg cttgataagt
     4021 tgctccatag cccatgcaag ctccagctgg aactgtcttg acatgaacca gagcagactc
     4081 caaggtcaag gccggtatca aatcataagg caaatccaag accgctccac ttggattgag
     4141 gccatacatg gcatctccca tacgaaccgc attgaaaata gtctctacat gccaaagagt
     4201 cgttgcagaa ttgctagcat gaaccagctc tggaacttcc ttcatactag ctaaaatagt
     4261 tttaaaccgt tctaactggg cattaaaata gtcatctgat tcctcatcag cagtagcaaa
     4321 gtgggtaaag attccttcaa cacaaacacc gtgttgttgg agcaaatctt gagcctgctc
     4381 aacctcactt gcctctctaa aaccaatccg tcccatccct gaatcaatct tgaggtggac
     4441 tgtcaatcca gttaggtcca cttccttatc taagagtgct tgaatccact ccagtccagc
     4501 cactgtcaag gtgaagtcat attctttagc tagagcaaca gcttcgattt cagaaactcc
     4561 taaaatgagg attggcttgc tgagtccagc ttgtctgagt tcaatggctt catcgatatt
     4621 ggaaacgcaa aagccatcaa catcatcttg aattgccttg gcaacggcaa cagctccatg
     4681 accataagca ttggccttaa ccacagccaa cttgagcgtt ccttgaggga tatgagcccc
     4741 catttgctga atattttgtc gaatagctcc cagatgaatc agagccttgg ttggtctatg
     4801 tggactagct ttcatgattt tcctccaaaa tgacactggc tgtcacaaac tgatcggtgt
     4861 ggctgataga cagccaaatc tttcctgaaa atggtgcctg actaaaataa ggcgccccac
     4921 gttcattgtt caagacttcc aaatcctgaa aaccgagctt gctaatgccc gttcccatag
     4981 ccttggaaaa ggcctcctta gccgaccagc gaccagctaa atattctatt tgcctgcgtc
     5041 ctttgagact ggtgaagcgc tccatttcct gagcggtcag tacacgctta gcaaatcctt
     5101 catgtcgtgt aactgcgctt tctatcgaag ccaattcttc gatgtcaatt ccgtgtccaa
     5161 ctatcattct catcaaaagg agttgagatt ccccaactcc atccttttca cttattttgt
     5221 caaggtaaca taaatctctt ctaccaaggc ctctgtattt tcccaaccta ggcaagggtc
     5281 agtaatagag caaccaaaga tctctggttg gttttgacga ccatctgcta ggtaagattc
     5341 aatcataaat cctcgaaccg tctttttaat tttctcattc caatcacgat tctgcaaggt
     5401 ctggcgaaca attcgaatct gctccatata ttgcttgcct gagttatcat ggttggtgtc
     5461 aatgaggata aaaggatttt caagtcccat ggtttcatag cgttcaatgg cttggagtag
     5521 attttcatag tagtaattcg gcatataatt gccatactcg ttgactgctc cacggaggat
     5581 aacatgggcc aaaggattac ctgatgtctc aacttcctgc ccatgataaa ggaaggtttg
     5641 cttgttttga gcagcataga tggcgttaaa cataacaccc aaatttcctg aggttggatt
     5701 tttcatccct actggtgcat caatcccaga agccacaaag cggtgctctt ggtcttccac
     5761 agaacgagct ccaacggcat ggtagctgac caagtcatcc accaagatca gatttgacgg
     5821 ataaagcatc tcatctgccg ttgtcaaacc agtctctgta atcacgcggt agtgcaactg
     5881 gcgcacagcc tgcaagccat taatcaggct tggagcctta gaagtatctg gctggtgaac
     5941 taatccttta tagccgtctc cattggtacg aggcttagca gtatacacgc gcatgaccat
     6001 gaaaatctta tccgctacct tcttttgcaa ggcagataaa cggcgagcat attccaagac
     6061 cgcctcttca ttatcagaag agcaaggacc aatcaccaag agaatacggt catcttcccc
     6121 tgaaataata tctgccaatt ccctgtcacg gctttccttg agtctcaagg cttccgcaga
     6181 caattgggtt tcagccttga tgacttccat atcgatttct tgaccttttt caataaatgc
     6241 catcttattc tcctaacgtt ttgtaaattt ctctgacaag agcttctgtg ttatcccaac
     6301 ccaggcaagg gtctgtgata gacttaccaa atacttctgg ctcattttgt cgaccatctt
     6361 ccagataaga ctcaatcata aaaccacgaa cgaactgctt aattttttca ttccaagcac
     6421 ggttaatcaa ggtctggcgg acaattcgga tctgttcaat atactgctta ccagaattgt
     6481 catgattggt atcaatgatg ataaaaggat tttccaagcc cattttctca tactgggcaa
     6541 tggtatcaat taaattgtca taatagtagt tgggaatatt ttttccatac tcattaagag
     6601 caccacgaag aatagcgtgt gaaagcgggt tcccagttgt ttctacttct tttcctaaga
     6661 aaaggaaact ttgtttgttt tgagcagcat aaatcccatt aaacatgaca ttgagatttc
     6721 cagaggttgg atttttaaaa ccagtagaaa atcctgcccc acttgccaca aagcggtgtt
     6781 gctggtcttc aactgaacgg gcaccaactg ccatgtaaga aatcaaatca tctacaagcg
     6841 gaaggttttc aggataaagc atttcatcag cagttgtcat ccctgtttct gtgatgacac
     6901 gatagtgaag atggcgaacg gctttgattc cattgataag actaggcgct tctgtcgcgt
     6961 taggctggtg aatcaagccc ttatagccat ctccgttggt acggggtttg gcagtataaa
     7021 cacgcataac cataaagata cgatctgcca cttcttcttg taggactgcc aaacgcttag
     7081 cgtattcaag gacagcttct tcgttgtcag atgagcatgg cccgattacc aagagaattc
     7141 gctggtcttc tccacgtata atggcttcta gctcttgatc tcgctgtgat ttcctctcca
     7201 aagcctgacc ttctaatttt gacaaggcac gaacttcttc tatatttatt ttagagcttt
     7261 ttgctgtaaa taccataact catctcctta taaagcaaac ggatacccag taaaaattta
     7321 cttttcacaa gatatccgcc tctaaactat ctcattttat tgtcttttac cgtgacagtt
     7381 tttaaatttc ttaccagaac cacatgggca aagttcattg cgtccaatct ggctcaaatc
     7441 caaatcttct ggcatacttg cttggtgagc agcgatattg cgagtcgctg ttgtactgat
     7501 atgacgttct gcctgtggtc tttcttgttc atgaatttgt gctttcatca tcaagcgtgt
     7561 cacatcaaac tcaatcgaac caatcatatc attaaacata cggaaacctt ctgcctgata
     7621 ctcaacaaca gggttgttct gagcatagcc acgaagtcca accgcgttac gcaattgatc
     7681 aagggcatcg atatgatctg tccacttgtt atccaccact cgtagaatca aaactttttg
     7741 gaattcttta actgcttctt catcgcgtag ttttgaaacc tgactatcgt aaaccttcaa
     7801 ggaacgttgg aaaagctctt ccttgatggc cttatcagac aagcctgaca agtcttccat
     7861 cgtaatagaa tcttcaggaa gcaagttgta cttagcaaag ttcaaaattg cctctagttt
     7921 ttcatcttgt ttggcacgcg catgaccatc aacgacacgt tcaatcgtgc gtttgatcat
     7981 agactgaatt tcaggtgcca agtcacgatc tgcagtgatg acatcgtaac gttgagcata
     8041 gataatctca cgttgttcac gcatgacatc atcgtattga aggacttgtt tacgggtatc
     8101 gtagttattt ccttcgacac gtttctgagc tgcttcaacc tgacgcgtca acatgcgaga
     8161 ctcaatggcc tcttcagaca tgttgagacg ttcaaagatt cccttcaagc gttcagaacc
     8221 aaaacgtttc atcaaatcat cttcaagaga taggtagaat tgtgactcac ctggatctcc
     8281 ttgacgacct gaacgtccac gaagctggtt atcgatacga cgactttcat gacgttctgt
     8341 accaataaca caaagtcctc caagttcacg aacaccttca ccaagcttga tgtcggtacc
     8401 acgacccgcc atgttggttg cgatggtaac ggcaccacgt tgaccagcat tcatgatgat
     8461 ttgggcttct ctatagtggt ttttggcatt caagacttcg tgaggaacac cagctgcaac
     8521 caatttctta gaaatgtagt cactagtttc aaccgctact gtaccaacca agacaggttg
     8581 acccttttgg taacgagcct taacgtcttc gacaaccgct ttaaacttag attcgatact
     8641 tgcataaaga aggtctgagt ggtcaatacg ttgaacagga cggtttgttg ggattggaat
     8701 aacacgaatg ttgtagattt cacgaaattc ttcttcctca gtcttacctg tacccgtcat
     8761 accagacaat tttttgtaca tacggaaaag gttttggtac gtgattgagg cagatgtctt
     8821 ggtttcatcc tggattggca caccttcttt ggcttcaata gcttggtgca atccatcaga
     8881 ataacgacga ccttccatgg tacgacctgt aaattggtcg acaatcaaga tttcttgctc
     8941 ttcgctcacc acatagtcaa tatcgagaag catgatgtag ttggcacgaa gggcgttatc
     9001 gataaagtgg gtcaaagcca cgttttcgat gtcatagagg ttttcaagtt tgaagtagct
     9061 ttcagccctg tcaatccctg aatcagacaa accaatagtc ttagactgca catcgatgat
     9121 gtagtcatct ttgttcaaag attttacata gtggtctgcc atgtgataca actgactggt
     9181 ttcaaccgca ttggcacctg atacaatcaa aggtgtacga gcctcgtcaa tcaagataga
     9241 gtcaacctca tcgaccaagg catagttaag cggacgttgt accatgtttt cagcgcgaac
     9301 gaccatgttg tcacgaaggt agtcaaatcc gatttctgag ttagttgagt aagtaatatc
     9361 acactcatag gcttcttttt tctccattgg agatttggta gccaagttaa tccctactga
     9421 caaaccaagc caagagtaca attcacccat ctcagtcgcg tcacgttctg acaggtattc
     9481 attaaccgta actacgtgaa cccctttacc tgaaagggca ttgaggtata ccggcatggt
     9541 cgcagttaag gttttccctt cccctgtacg catctctggc acgtcaccat ggtgaagaac
     9601 aatccccccc atgacctgaa ccttataagg gaagagacct aggacacgtt tggcaccttc
     9661 acggacaacc gcaaatgctt cgtaaagcaa tgaatccagt gattctccat tttgataacg
     9721 ttccttaaat tcaactgttt ttgcttttag ttggtcgtca gtcaaagcag ccatttggtc
     9781 ttcgtatttg aaaaccttgt cagccatctt ttccagacga cggatttctc ctttatcatt
     9841 ttcgataatt gtttttaaaa tattagccat gtttttcctt actttaaatt ccgaatattt
     9901 tagaatgttc ctttaatttt agcacaatta ctgattattt tcaaggaaga atccccattt
     9961 tgaaaaggaa aaagaggtta gttttcaagc taacctctcc gacttttatg actgtttaat
    10021 tgccaaaaat cggcaaaatg gcaaatgtga taaataagtt aatccaaaga gaaagacagc
    10081 aaatcagtcc aaaaacaaag agactgactt tcttggacag caaggccatg agaatggaca
    10141 gaattccaaa agctagcaag attttctgta tgatgaagat gtcaatcctt acccccagaa
    10201 tcgctctatc ccaagggata aagaagaaag acagccagat cagcagaact aaaccaatat
    10261 aaaccttgga atagcgtgta ataaatgatt ttagatgtgc cataagccat ctcctaggat
    10321 tgtatatcct ttacatttgt atatgtccat tttcgacaac taatacatct gtacaaaggt
    10381 ctgaaatatc ttccgatatg tgcgacgtca ggataaccag accattttct tttttcaggt
    10441 aagataaaat gacctgtttg gttaacctca cactcttctc atccaaagca ttcataggtt
    10501 catcgagaaa gagtatagaa ggagaggaaa taaaggcttg aatcaaggcc attttttgct
    10561 ttgttcccaa ggataaatga cggtattcaa cgtcttcaaa ttcctgtaaa tcatagtatt
    10621 gaatccaata ggcaattctt ttttccgtaa ctttagatga aaaatacctt aacagttcca
    10681 aattttctct cagggataaa tgagataaaa actcgacttt ttcaattaaa attcctgcat
    10741 cctgaatata atgatttttt atcccgtaga ctttcccgtc ttgaagaact tttcctttgt
    10801 caagcttaat atagccagca agtaccttta aaagaaccgt cttgccagat ccattatcac
    10861 ctttaagtcc ataaattttt cctgattgaa acaccaaatt caactgattt aaaataggtc
    10921 ttttcccata aattttctgt ccatttataa tttcaagtct catcgtttat cctttcttaa
    10981 atttctcttc caagcgacta acaatcaaca taactaataa acttaagagt agtaaataca
    11041 ctgttacaat atgatccatc atccattctt gtcccacaaa tactaaaaaa tagagaaaaa
    11101 aggaaaaacc agcgcccgca ctaatcagtg ctatcagata agacagtagt aagtacaaca
    11161 tcattaactg agcaagtaaa aagaaaagtg cgactgtttt gaaatgaatt cctagcggaa
    11221 gtaaaccaag gaaccagaca aacaaatctt gagtaaaaaa tttagaaatg acaaccaatc
    11281 gtttccttgt ataatcgaaa aaggagcttg attgatagcg aatcaagtga tggtaatggt
    11341 ctgccaaatc actttcaagt aaaatgacag agagccatcc taccatgaaa agcgaaaggt
    11401 ttaacaagag tttggggatt tctaaattcg cttcagaata gtcattatag gaaaaaattg
    11461 aaatcaattc tctcttgaaa aagataacag catcctgctt ttgaaccgct gttgacaata
    11521 gatggtttat caaaatcatc atcagaacta tacgaagtag taaaacaatc tttctcttta
    11581 gcaaaatatt gttaaaattc ttaaacatta tcttcatatt tttcaagcac catgtaaggg
    11641 acaatataaa ggatataagg agtaaagagt ttcatcaaac ttacatcccc atagctagct
    11701 tgcatcaaac tcgtcatagg aaccatatag taaggcaagg cactatagag cagcatagaa
    11761 ccaagccaaa gaaacatcaa ataggtgatt gccgaacgag tcacattccc cacataatca
    11821 actatttgta aaaaatagat tgcattgatg aaaataccga ttagcaggac acaagtaaag
    11881 aacaaatagc tttttatctc tccatctagg agtctttgta aaccacttcc atcagaaaat
    11941 agagaattcc atccaagagg agaaaaagtc ccaaggaaat aggttataat tgcaattgtc
    12001 agcacagtca ctaaatatat caaacaaggg atacttgcaa cttgcaaagt caactttctt
    12061 tttaaccctg gatagctcac ttctcttcca atactcaatc gtaaaacttt atttttcagc
    12121 tcaatatatt gaaaacctag caaaacaatg atgattggaa taataaatga ttgataaaaa
    12181 cctagattga actggagaat acgaaaatct aatgctgatt ttaataagtc atttttaatt
    12241 gcttgtccat cgaatttagc tagatcgggc gcatgaatat caaaaaagaa ataagtcatc
    12301 aaaacgtcac gataaaccaa agcaagaaaa agcaaagtaa gcaagacata aacaaattta
    12361 tgccttgcca aagttaagag aggaatcttc ataaattata cctactttac gaattaattt
    12421 ggtgaccaac tacctgaaat ggcagctgat aaatcccacc aattttgtct tgccatatct
    12481 gctgcataaa catagccaac cgttgcccaa ttaccatgag ttgaacgagt accacaggtt
    12541 gttaacgatt ctccactacg agcttctcca ttagaattta ctatacgatg cttaacagtc
    12601 atgggatgta aatttctaca aggatttaag ttcatgatat attccgcacc ttcattttct
    12661 ttagtcaaat aacctgttct cttataactg gtagtaataa caaaattact aaaagcacct
    12721 atctgatttg cttctacgaa agtagttcca acagcactta tcattaaaac aggaataacc
    12781 attttcaata atttcttaat tttcattttt tctgtttcct ttcatttttt attcaagaag
    12841 attccttata acttctattt taaatataga cttattctaa acgatggtat atcatacaaa
    12901 ttcctccttt acttattata tatagactct aatttcttta tccccaaaac catgtttcaa
    12961 accagataag ttgaatccaa ctccaaatca aaaatccaga gtttttcggt aaattcttca
    13021 aatatttttt aaagcccatg actttttccc tcctttttga tataataata ccaccttttt
    13081 ctacgttttt tataaatgta gaaaatattc acatttacct aggaggaaca atatgagatg
    13141 ggattatgga caaattttta aagaaattcg aaagtcaaaa ggattgaccc aacaagatgt
    13201 atgtggacaa gtcatacatc gaacaactct aacaaatatt gaacacggta aagttattcc
    13261 cagttttgaa aacatggtat ttcttcttga acaaattgat atgagcttgg cagaattcaa
    13321 gtatatatgc aacgaatacc atcctagtaa aaggcgagat attattgtag agagccaaaa
    13381 tccgtctact tttcaagata ctagaaaaat ggttgaactc actgagaaat gtcaaaaata
    13441 tcttaagaca catcacgatg ttcctattca aaatatctat cgtcatacaa aaattgtcac
    13501 agagttacga actaaaggat tcaaaaacaa ccacgtcttg aaagatttgt atgaagaaat
    13561 ttgggactat cttgaaccta tggatacatg gtacattagt gatttgaaat tgcttggaac
    13621 cattctcttt ttctttcctt ctgaaaatct tccccttctt attgatagaa ttatgaaaac
    13681 catcgagaaa tataaatact tccgagaaac aaaagcattt ttatcatctt ttttagccaa
    13741 tctctccact gtatattttc aacatcattt attcaaagaa tgtgaaacaa tcaccctaca
    13801 acttttggta ttagcagaag aattaaaaat atacgatatt cttggattct ctcaagtacg
    13861 cttgggaata ctacaacata actccgattt gattgataaa ggaataactt tattacgact
    13921 aaccaaagaa gaggcattag ttaaaatact cgaaaaagaa attaatgatt tttcaaacct
    13981 ataatttgta ataactctca tcattttatt atagtagatt gtaatagaat gtaatagaat
    14041 gtgaacgaat caattagggg atctaaagca ttttatacca atgttttata agttgtattg
    14101 tattattcca tattcaatcc actatacaag atgaatattt ctctcaagtt tcataatcaa
    14161 aataaaaatg actgtatcta tagctccata aacaaatcat agatacagtc attttttagt
    14221 tcctacacct tcctttatgc acacctttag atttccctag ttcccgcctc aagcgaatca
    14281 tttttttgaa aaagacatag gctaaccaat cactagcaaa agcgataagt agtaataata
    14341 gccaaatacc ccataacttg atatctgtca aatttctcaa gacgatattg aaaaacagaa
    14401 ctgaaaaaac tgtccaagca aggctaaaaa gagcatagag ggtgatgtaa atccagtaaa
    14461 aatagtaaaa aattgggaaa aatttacttt ctctattatc cttgtcaatc cagctgaaaa
    14521 agtaaaaaca gggtaataag attatcattt taaacaagtg ttccatcaca agcctccttt
    14581 tttaaattgt tttctttagt ttcgttctat taaatgttat taccaatata aaccttggaa
    14641 tagcgtgtaa taaatgattt tagaggtacc ataagccacc tcctacaaat agaaaccgat
    14701 ataaatcaat gccttccacc cttagacttc cctagttcct gtctcaagcg aaacatttct
    14761 ttgaaacagg aataagttaa ccaattcata ccaatagcta gcagaataaa aagaaaccaa
    14821 atgccccata acttgatatc tgtcacattt ctcaagacgg tattgaaaaa cagaactgaa
    14881 acaactgtcc aagcaaggct aaaaagagaa tagaagggga tgtaaaacca gtaaaaataa
    14941 taaaaaattg gaaaaaactt actatttctg ttggcctttt caatccagtt atcaaaataa
    15001 aagtacggtg ctaaaagtaa gaatttaaac aaatgttcca tcaccgacat cccccttctt
    15061 ttgatagcgt tttctattat tttattatat caaaaaaatc cggaactgtc attccagatt
    15121 ctactttttt atttgcgttt tcttgcgatg agatgaatcg gtgttccctc aaaaacaaag
    15181 gccttgcgga tttgattttc caagaaacgc aggtaagaaa agtgcatgag ttcttcttca
    15241 ttgacaaaga tgacaaaggt tggtggtttg gttgccactt gggtcgcata gaaaatcttg
    15301 agacgttttc ctttgtctgt cggtgttggg ttgatggcaa tggcatccat gatgacatcg
    15361 ttcaagacag ctgatggaat acgtgtattt tgactttcgc tgatttgctt aatcatctca
    15421 ggaagtttgt ggagacgttg cttggttaaa gctgatacaa agataatcgg tgcgtaaggc
    15481 aggtattgga actgctcacg gatatcttct tcccagtttt tcatagtgtg gttatctttt
    15541 tcaagcgtat cccacttgtt gaccacgata atcatccctt taccagcttc atgagcaaat
    15601 ccagcgatac gcttgtcgta ttcacgaatc ccctcttccg cattgatgac cattaagacc
    15661 acatctgaac ggtcaatagc acgcatggca cgcatgacag agtacttctc agtattttca
    15721 taaaccttac cagacttacg cataccagcc gtatcaatca tggtaaactc ttgaccatct
    15781 gtatctgtaa agtgggtatc aatagcgtca cgagttgttc cagcaacagg actggcaatg
    15841 acacggtctt ctcccaagat agcattaatc aagcttgatt ttccaacgtt aggacgacca
    15901 atcaagctaa acttaatgac atctggattt tcttcttcat attcatttgg aaggttttcc
    15961 acaatcgcat ctagtacatc ccctgtaccg ataccatgga cagatgagat aggcagtggt
    16021 tcacccaaac cgagagcata gaaatcatag atatcatttc tcatctcagg gttgtccacc
    16081 ttgttgactg cgaggataac tggtttgtgg gtcttataaa gcttacgagc tacgtattcg
    16141 tctgcatcag taattccttc cttaccagac acgacaaaaa cgataacatc tgcttcttcc
    16201 atggcaattt ctgcctggtg cttgatttgt tccatgaaag gagcatcgac atcatcaatt
    16261 cctcctgtat caatcatgct aaaagaacga ttgagccact cacccgttgc ataaatacgg
    16321 tcacgtgtca ctccttcgac atcttctaca atggagattc gctcaccagc gatccgatta
    16381 aatagggttg atttcccaac attgggacgt cctacaatgg caatagttgg tagggccata
    16441 atttctcact ttctacaata atttcttctg ttcaagattt tttctagttg agcttggttc
    16501 agcttgacca aactgttctg ctaggcgctg actccagctt gtggtcgcac gcgccccagc
    16561 atagtcagcc tgaacacggt cataagcttg gattgcctca gttgactgtt cttggtattc
    16621 ttcctcaaag acaacattct ctagtggcag tctcggtttc atatcatgat gttgatttgg
    16681 cacacccagt gccatcccaa agacagaata ggtgtagtca ggtaggttaa agagctctgc
    16741 cacttcttca gacttgtatc gaaccaaacc gataatcaca ccaccatagc ccaagctttc
    16801 agctgccaac aaggcgtttt gtccagcaag agctgcatcg accgaactaa tcaagagacc
    16861 ttccacacct tggggttgga aggtgtcggt atgaagtctg gctccctttt ctgctcggtt
    16921 caaatctccg acaaagagaa ggaaaacagc agactggcga atggcttctt gaggtaccaa
    16981 ttcatacaag gcatctttct tctcttgact tcgtaccaca atcacagagt aggattggaa
    17041 attcttccaa gatgatgcca tctgggctgc tgtcaaaatc tcatttaagt ctacttgggg
    17101 aatttcttgc tctttaaacc tgcgcactga agtatgagcc ttcatcaatt taatggtttc
    17161 tgtcatcgac ggtttactcc ttctaaacga gtctcctcag ccaaataacg gatgcgttcc
    17221 atgacccgtc tggcttccca ggtttcgtca tttccatgtt tcactttcgc aaaatgcttc
    17281 tccaaatctt caaagttgaa gttggatgtg aaaaaggtcg gtaaattttc ctgcatccga
    17341 tattggagaa tgacctgcag gatttcatca cgcacccaag cggtggattg ctcggcgcca
    17401 atatcatcta aaatcaggac ctcagacagc ttaatctcat ccaccaaggt cttaacattg
    17461 ccatcactga tagcattttt gacatcaatg acaaagctag gatagtggag gagagttgat
    17521 gaaacaccac gtttttctga taaatcatga gctaaggccg ccaccatgaa acttttaccc
    17581 acaccaaagt ctccatataa gtaaagacct tttcgaatag ctggatattg ctccacgaag
    17641 gctagtagct tttcaaaaac tggtaagcgc cccaaatcat ccaagtcaac ttgagccaaa
    17701 ctagctttct tgagactggc tggtagattg attaacttga gacggttctt aatagccgct
    17761 tctttttcag ccgcgattag ctcaggagtt tcttcatatg aaacatctgc atagccatga
    17821 ttcttaacca aaatcggctt gtagcctttg gcaatataat ccgtatcccc acggagaaac
    17881 ttgtcacgct cggtgatgta ctgattaaac ttggagatac tgcgatttaa ttcctctgga
    17941 gtcaaggatt cttgctggat aaaagccgca acatcagggt ccttcatgat tttctggacc
    18001 aaatcttgat aataaaaacg gctgggttga cgtttgagta cgtctccgac actttccatc
    18061 taatctcctc ctttttctaa tcgagctaat agttcttgct tcttacgttc tagttccaga
    18121 cgagtttcct cgctggtttc attcttatat tcaggattac tccatttagg aacattggtt
    18181 tttactgggg cagtctgatt ctgtttttgt gtttttgctt tctgtcctcg ctcacggatg
    18241 cgcaagactg ccttttctgc cgaatgaatc ttttgatagg catagtcatt ggctaccttc
    18301 atggcatatt tctcattgat atttgccgaa tcgaccttat taaaggtcaa taaaagaatg
    18361 atattgatga cttcgtccag caagcccaag ccagccatct gttgcaagag ttctctttct
    18421 gtttgggtaa tggttccctt gcgtgtttgc ttgatttctg ccaagaactg cagggcagtt
    18481 ttacttttgg cttctttgat aatggttgtt tccttaagac taaagtcaga ggaaactggt
    18541 ttttgagcaa ttttttcacg catgcgtttg gttgaaataa cctgagaaac agctgttgac
    18601 ttggccaatt gataggtttc aaaccaagtc catttcttct cctcggcaat agcaaagagg
    18661 tttaagacat cggactgctc atccgcaaaa cgaagtccat ctcgagccat cagctggcga
    18721 aaatgttcca agtcaaaatc attggccact ttcttcttga gaccaaggtc ttcttgactg
    18781 cctagttctg ccaattctgg aaagacttga ttgagtgaga caggtatttc ttcaccatca
    18841 gcactttcaa ctttcaaatc ctccacagca gagtcgccaa tctttttctc taagagtctg
    18901 cgataaacag gatgctccaa gaagtcttga ctagatagag gagcatggag ggctagctga
    18961 taaacatccc ccttttgata gagggtcaag agattaaaag cagataagat tttcaatgat
    19021 tttatcagtc tatccatccc aaagttgaga tgattgagga tacttgaaaa aagatattcc
    19081 tttctaccat tatcccaaaa actgattgta taaagataaa ggctcagtgc ctcctgaccg
    19141 ataatcggga ggtagcactg taccagagat gaggtatctt gcgacacccg attattcttt
    19201 agataagaaa aacggtcaat tggcttcatt tatctttcct ttttcttttt agaggactgg
    19261 gtgatttgtt ggagcaagct ctctaactca ctgacatcct taaaactacg atagacacta
    19321 gcaaaacgta cataggtaat ctcgtccaat tcagccaact cctccatgac gagtgaacca
    19381 atgtcctcac tttgaatttc attttcattt cgaccacgga gtttctgttc gatacgattg
    19441 actaccatgt tgatttcatc acttgacaca ggacgtttct gggctgagcg gataatccca
    19501 ttaaagattt tatctctgga gaattgttcc cgtgtgccat cttttttaac aaccactaag
    19561 gttctttctt ctactcgttc gtaggttgta aaacggtgtt ggcactcgtc gcactctcgt
    19621 cttctacgaa tggtgttccc ttcttctgct tggcgactat cgataacact tgacttggta
    19681 gccccacatt ttggacaacg catcctttcc ctccttatcg ttttcttttc attataccat
    19741 tttttaagcg attcccaaaa caattcttct ttttgcttga caagtttttt gttttgttgt
    19801 attatttaat taagacaaaa ggataagaga aaggagacta agatgtcctg gacatttgac
    19861 aacaaaaaac ccatctattt acagattatg gagaaaatca agcttcagat tgtttcccat
    19921 acactggaac ccaatcaaca acttccaacc gtgagggagc tagctagcga ggctggtgtc
    19981 aatcccaata ccatccaaag agccttatca gaccttgaac gagaaggatt tgtctacagc
    20041 aagcgaacaa ctggacgatt tgtgactaag gataaggagc taatcgccca gtcacgcaaa
    20101 caattatcag aagaagaatt ggaacacttc gtttcctcca tgacccattt tggctatgaa
    20161 aaagaagaac taccaggcgt agtcagtgat tatattaaag gagtttaagc ctatgtcatt
    20221 actagtattt gaaaatgtat ccaaatcata tggagcaaca ccagcccttg aaaatgtttc
    20281 tcttgacatt ccagctggaa aaattgtcgg ccttcttggg ccaaacggct caggaaaaac
    20341 aaccctgatt aaactaatta atggcctctt acaaccagat caaggacgtg tcctcatcaa
    20401 cgacatggac ccaagcccag caaccaaggc cgttgtagct tatttgcctg atacgaccta
    20461 tctcaatgag caaatgaagg tcaaagaagc cctaacctac ttcaagacct tctataaaga
    20521 tttcaatctt gaacgcgccc atcatctact tgcagacctg ggcattgatg aaaatagtcg
    20581 tctcaagaaa ctatcaaaag gaaacaaaga aaaggttcaa ctgattttgg ttatgagccg
    20641 tgatgctcgt ctctatgttt tggacgaacc cattggtggg gtggatccag cagcccgtgc
    20701 ttatatcctc aataccatta tcaacaacta ctcaccaact tctaccgttt tgatttctac
    20761 ccacttgatt tctgatatcg agccaatctt ggatgaaatt gtcttcctaa aagacggaaa
    20821 agtcgtccgt caaggaaatg tagatgatat tcgctacgag tcaggtgaat ccattgacca
    20881 actcttccgt caggaattta aggcctaagc aaaggagatt atttatgttt tggaatttag
    20941 ttcgctacga atttaaaaat gttaacaagt ggtatttagc cctctacgca gccgtgctag
    21001 tcctttctgc cctcatcgga atacagacac aaggctttaa aaatctacct taccaagaaa
    21061 gtcaggctac tatgctactt tttctagcta cagtctttgg tggcttgatg cttacacttg
    21121 ggatttcaac cattttcttg attattaaac gcttcaaagg tagtgtctac gaccgacaag
    21181 gctatctgac tttgaccttg ccagtttctg aacaccatat catcacagcc aaactaatcg
    21241 gtgcctttat ctggtcattg attagcaccg ctgtattggc tctaagtgct gttattattc
    21301 tggctttaac agctccagaa tggattcctc tttcttatgt gattacattt gtagaaacac
    21361 atctccctca gatctttctt acaggtatat ccttcctact aaatactatt tcaggaatcc
    21421 tctgcatcta cctggctatt tccattggac agcttttcaa tgaataccgt acagcactcg
    21481 ctgttgcagt ctacattggt atccaaatcg tcattggatt tattgaactt ttcttcaatc
    21541 ttagttctaa tttctatgtc aattcactgg taggactcaa tgaccatttc tatatgggag
    21601 caggtatagc cattgttgaa gaactcatat tcatagctat cttttatctc ggaacctact
    21661 acatcttgag aaataaggtt aatttgcttt aaataatttt tacctagata tgtaacatac
    21721 tcatagaaca aaagagacca ggcaaaaagt ctttacaatt agaaaacgca tagtatcaag
    21781 tgttaaaaat ccttgatatt atgcgttttt tgtgagctga cttatttcct ttcactatat
    21841 cgcaaaatga aataagaacg gaacgatggg attttggaat tcaaatcaat ttataagaat
    21901 gttttagaag taatattatc ctattccaga ttcagttcac tatacaattg agttttcaag
    21961 caacctgttt acataatgtg tacataatta ggttcgtgat tccacccttt tcacctttaa
    22021 aaacctcgct ttcgcaaggc tcttctattt ataagataag gcacgtttaa aggttttcca
    22081 aatccctaaa tcatccgttt gaagaacgag actagcatac atgcgtccga taaatcctgt
    22141 tgctaccacc gcaaaaatca ctgtaatagc aagtgaaatc catgcttccg ctccctccgc
    22201 atagccatta atcgttcgaa acggcataaa gaaggtcgaa ataaagggaa tataagaacc
    22261 aatcttcaag aggagattgt caccagctgc acctagagct gtcactccaa aaaaaccacc
    22321 cataatcaaa atcatcaaag gcgacaaggc tttccctgag tcttcaggac gagaaaccat
    22381 agatcctagg aaggctgcca agactacgta catgaaaaga ctgatcaaaa taaagagcaa
    22441 ggtattcagt gagatagcat ctcccaagtg atccaaaata ccagactgag ccaagaatgg
    22501 caaatcttta aagagcaaaa cggcagccag accacctaca acatagatcc caatatgcgt
    22561 taaaatcact agaaacagag ccatcatccg cgcatagaaa tagtgacttg cccttatgct
    22621 agaaaagacg acttccataa ttttggtgcc tttttcactg gcaacttcct gagctgttac
    22681 acccgcatag gtaatcagaa tcatataaag aaagaatcct aaggcacctg ctgcaattgt
    22741 ttgaataaac tttttatttt ccttggcttc atcaatcttt tctgtgaatt gaattgtctg
    22801 cgctaagcgt ttttcctgct cttgagacaa ggaagcagtt gaacgattaa gctgattttg
    22861 cagttcattg agtgtacctg taacctcaaa tttaattcca ttttcaagcg atgtttcgcc
    22921 atgataaact gcctttagaa cactatcttc ttgatcaatg gtcaaataac cttttaattt
    22981 ttcttcttta attgcttctt tggcacttgc ttcgtcttta tagtcgaagt taacaccatt
    23041 tacattcttc agtccttctg ctacagatgg cactgttgtc actactgcca ctttattatt
    23101 tttagccata gaagaacctt ggagatgccc aattcctaca gagattccta aaaagaggaa
    23161 cggcgaaatc accataaaga agaaactcca tgactcgaca tgtcgaagat aggtttcctt
    23221 gattacaacc cacatatttc tcatacttcc actcctgatt ctagtttaaa gatttcatcg
    23281 atagttggcg cttgttggtc aaatgttgcg atatattgac cttgagtcaa gattgggaag
    23341 agttcccttc cagcgctctc atcctccaaa atcaatttcc aactgccttg tttggtcaag
    23401 ctcacctgtt tgacatgagg aagattttcc aattcttcct tgcttcgttc acttgaaaca
    23461 aagagacgcg ttttcccgta ttgattgcgg acatcctgaa ctggtccgtg caagaccaca
    23521 cggccatctc gaatcatcag aatatcgtca caaagttcct caacattggt catgacatgg
    23581 tcagaaaaga taatggttgc tccgcgctct ttttcctgaa aaatgacttg tttgagcaat
    23641 tctgtattaa ctgggtccaa tccactaaaa ggctcatcca agataatcag gtctggttca
    23701 tgaatcagag taataatgag ctgaatcttc tgctgatttc cttttgacag actcttgatt
    23761 ttatctgtca gctttccttt tacttccaac ctcttcatcc attgagggag tttttctttg
    23821 acttctttgg catccatgcc ttttagagtc gccaagtagc gaacttgttc aagaactgtc
    23881 aatttaggca tgagactgcg ttcttcaggc agataaccaa tccgagcata gatctcctga
    23941 cgaatatcct gaccatccag accgatttct ccctgatatt ctaggaattt taaaatacta
    24001 tggaaaatcg ttgtttttcc agcaccattt tttccgacta gtcccaaaat acgacctggt
    24061 cgcgcttgaa agtcaatacc aaacaaaact tgcttggatc caaaactttt ctctagactt
    24121 cttacttcta gcatctttca cctccgaaat ttcttgcact cattatactc ctttttgata
    24181 gcctttacaa tgttttttgt ccatttttag aagactattg ctgtgtaaaa tatggcctgg
    24241 agcactttta tactcaatga aaatcaaaga gcaaactagg aagctagccg tagactgctc
    24301 aaagtacagc tttgaggttg cagataaaac tgacgaagtc agctcaaaac actgttttga
    24361 ggttgtggat agaactgacg aagtcagtaa ctatacgtac ggcaaggcga agctgacgtg
    24421 gtttgaagag attttcgaag agtattagtg ataaatccat tatacagcag caaacttaat
    24481 ttataccttc cgctcctcaa ctgtctattt ttaatcctga attgttattt gagtaactcc
    24541 tttttcctcg taaagttttc ttcctctaaa acttctggaa aaaggctaat agtttcagac
    24601 aacattttta taagaaacaa gttcatctgt catttcaaga aggagtaatc ctttatctac
    24661 taatggacgg aacagaattc aaccgcttgt ccgatatgtt ttctaaggat tatatagtaa
    24721 aatgaaataa gaacaggaca aattgatcag gacagtcaaa ttgatttcta acaatgtttt
    24781 agaagtagat gtatactatt ctagtttcaa tctgctatat ctattatgca cacccctata
    24841 ggatctaatg aaaatcacaa caggctcatt catagatagt tacctcagga aactaagaaa
    24901 acgactacaa aggaagtcgc attcatcgaa aagtggatta acaactatcc taaaaaatgc
    24961 ttgaactaca agtcccccag agaagacttc tggatgacta acttgaactt gaaatttagc
    25021 aataattaat tcaccatcta actatattta gtaattattt cagaactgat taatattaaa
    25081 attaactaac aattcaaagg attcatacta gccataaatt acgtccatca gagagagact
    25141 cttactactt ttagatttta gtctttctag cttcagaata catctaaact ttagggaaaa
    25201 tgactattcg aaagcgcgaa tgcctcaaaa ttatctcaga taagctattc gaaacttaga
    25261 atgcttttaa atttatggaa ttgcgattat tcgaaaccta gaatgcatat aacctttagt
    25321 tgacagacct attctaagtc tcgaagggct atttactttc tattccttat caaaaaagac
    25381 tcattccccc tttctcctcc aaaatatggt atagtagaaa tatactatct atgaggagtt
    25441 tacatgtcac aggataaaca aatgaaagct gtttctcccc ttttgcagcg agttatcaat
    25501 atctcatcga ttgtcggtgg ggttgggagt ttgattttct gtatttgggc ttatcaggct
    25561 gggattttac aatccaagga aaccctctct gcctttatcc agcaggcagg catctggggt
    25621 ccacctctct ttatcttttt acagatttta cagactgtcg tccctatcat tccaggggcc
    25681 ttgacctcgg tggctggggt ctttatctac gggcacatca tcgggactat ctacaactat
    25741 atcggcatcg tgattggctg tgccattatc ttttatctag tgcgcctata cggagctgcc
    25801 tttgtccagt ctgtcgtcag caagcgcacc tacgacaagt acatcggctg gctagataag
    25861 ggcaatcgtt ttgaccgctt ctttattttt atgatgattt ggcccattag cccagctgac
    25921 tttctctgta tgctggctgc cctgaccaag atgagtttca agcgctacat gaccatcatc
    25981 attctgacca aaccctttac cctcgtggtt tatacctacg gtctgaccta tattattgac
    26041 tttttctggc aaatgctttg acacgtaaaa aatccgtttg gtttcccaag tggattttta
    26101 aagcgtagat taactatagc ttgatactaa atatactttg gtatggaaat catgcatatt
    26161 tttcgatagt gaagcgagga cttacctagc ctttccaccg tgatagaaac acctgaaatc
    26221 taatggtttc aggtgttcgg aaactttgag cctagtgtct caaagtttag gtatggaatt
    26281 tcgaagaaag tcgctaccgt ccgtaatcac ttaaggaaag gctcaaaaat attgttttca
    26341 accacaaaat ccgtttggtt tcccaagcgg attttgtgct ttattttgaa acttcttttg
    26401 caagaacaaa gttcccaagt gtggcagaac catttcctgc gactgctggc gtcacgatat
    26461 agtcacgcac atctggtact ggtaggtaac cattaagaag agatgtaaat ttctcacgga
    26521 cacggtccag catatgttgt tgagccatga cccctccacc aaagacaatc acgtctgggc
    26581 ggaaagtcac tgtcgcatta accgcagctt gagcgatata gtaggcttga acatcccaaa
    26641 cagggttgtt gagttcaata gtttccccac gtacacctgt acgagcttcc aaacttggac
    26701 cagctgcata gccttccaga catcccttat ggaaaggaca aacaccctta aactcttttt
    26761 caatatccat tgggtgtcta gcaacataat aatgacccat ttcagggtga cccacaccac
    26821 cgataaactc accacgttgg atgacgcctg caccgatacc tgtaccgatt gtgtagtaaa
    26881 ccaagttttc gatacgacca ccagcattgt tacgggcaac cacttcaccg taagcagagc
    26941 tgtttacgtc tgttgtgaag tacattggca cgtttagggc gcgacgaagg gcaccaagca
    27001 agtccacatt tgcccagttt ggttttggag tcgtcgtgat aaagccataa gtttttgagt
    27061 ttttgtcaat atcaatcggc ccaaatgaac caactgcaag accagcaagg ttatcgaatt
    27121 ttgagaagaa ctcaatggtt ttatcgattg tttcgattgg agttgttgtt ggaaattgtg
    27181 ttttttctac aacgttaaag ttttcatcac cgacagcaca gacaaacttt gtaccgccag
    27241 cttccaagct tccatataat tttgtcatga taaacctctt gtttttattt tctttattat
    27301 agcatacttc gaaagtctaa atgtctctat tttttagatt ttcctctgta aatcttacta
    27361 tctaataaaa acgaacaaac atgtcatttg ttcgttttca cattagagag gattgattag
    27421 attttcactt cgatcacagc atcccccttc gcaactgaac ctgttgcgac tggagctact
    27481 gaagcgtagt cagctgtatt tgtaacgata accattgttg tatcatcaag tccagctgta
    27541 gcgattttat ttgagtcaaa tgttccaaga acatcgccaa ctttcacctt atcaccttga
    27601 gcaacttttg cttcaaaacc gtcaccgttc atagatacag tgtcaatacc aacatgaatc
    27661 aaaacttcag caccatttct tgttttcaaa ccaaaagcgt gccctgttgg aaaggcaatt
    27721 gaaacttcag catcagctgg tgcatagacc acgccttggc ttggtttcac agcgatacct
    27781 tgtcccatag ctccacttga gaagactggg tcattgacat cagcaagagc gacaacatca
    27841 ccgacgatag gagttacaag tgtttcattt tgaagagctg ctggcgcaac ttcttctttt
    27901 tcttcagcca cttcagcttg ttttgcagct gcagttgcgt ctacttcatc ttcgtaacca
    27961 aacatgtaag taagagcaaa accaagggca aatgatacag ctaccataag aaggtattgt
    28021 ggaagttgtc cgttaccaac ataaagcatt gtaccaggga tgatggtgat accattacca
    28081 gtaccagcaa gtccaaggat agaagccaat ccaccaccga ttgcaccagc aatcaatgaa
    28141 aggaagaatg gtttacggaa gcgcaagttc accccgaaga tagcaggctc tgtaatacct
    28201 aggaaggcag aaagagcagc cgggaaagca agtgttttca gttttggatt ttttgtttta
    28261 acaccaaccg caacagtagc agcaccttga gctgtcatag cagctgtgat gatagcgttg
    28321 aatgggttag catggtcagc agcaagtaat tgcacttcaa gcaagttgaa gatgtggtgc
    28381 acacctgaca cgacgatcaa ttggtgaacc ccaccaatca agaaaccacc aagaccaaat
    28441 ggcatgctaa gaatcgcttt tgtagcaata aggatgtagt tttcaacaac gtggaaaact
    28501 ggtccaatga caaagagtcc aaggatagac atgaccaaaa gtgtcacgaa tggtgttacc
    28561 aagaggtcaa tgacatctgg aacaaccttg cggacagctt tttcaaattt agctccgaca
    28621 accccgatga tgaaggctgg aagaacggaa ccttgcaaac caacaacagg gatgaaacca
    28681 aagaagttca tcgctgttac ttcaccacct tgagcaactg cccaagcgtt tggaagtgag
    28741 ccagagacaa gcatcatacc aagaacgata ccaacggcag gatttccacc aaatacacgg
    28801 aaggttgacc acacaaccaa acctggcaag atgatgaagg ctgtatctgt caagatttgt
    28861 gtgtaagttg caaagtcacc tggaagtggc atttcaagag cgttgaaaag accacgcaca
    28921 cccatgaaga gacctgtcgc tacgataact gggatgattg gaacgaaaac atcaccaaaa
    28981 gtacggatag cacgttggaa ccagttccct tgtttagcaa cttctgcttt catgtcatcc
    29041 ttagatgatg ttggtaatcc aagtacaaca acttcatcgt acattttgtt aactgtacct
    29101 gtaccaaaga taatttggta ttgccctgag ttaaagaaag caccttgaac tttttccaag
    29161 ttctcaatca cttctttatt gattttctct tcatctttga ccatgacacg tagacgtgtc
    29221 gcacagtggg caacactatt gacattttca cgtccgccca aggcatcgat gacttttttt
    29281 gcaatttcct gattgttcat ttgcaaaaat ctccttatat aacattttgt tcttgtttga
    29341 aagcgatttt attcgccctt acgactatta ttttatcatg ttttaaaaat atgtcaagcg
    29401 ttttgcagaa aaaatattct atctacttag tgggcaagct ttagattgat tgtttttgac
    29461 tgtttcatca ggaatttctt gaaaaataag tttgaaacct tggttaaaaa gtcttttatt
    29521 tcattatctt tcacattttc gtaaaaattt gattgatttc ctgtatttat tttatgataa
    29581 tcgtttgaca gttttttctc ttttttaaca taaagggctt gcatttttta tcgaaaacag
    29641 ttactattaa aagtgataag atttttggag gaatgaatgg aatggacaac tgagcgtcgt
    29701 tacagacttt atcaagattg gacgcaagaa gaaattcaac atataaagga aaatatggca
    29761 caatctccat ggcatactca ttaccatgtt gagccaaaaa caggacttct caacgaccca
    29821 aatggctttt cttactttga tggcaagtgg atcctctttt accagaattt tccttttggt
    29881 gcagcccacg gtttaaaatc ttgggcacag ctagaaagtg atgatttggt tcactttaga
    29941 gaaactggag tcaaagtttt gccagatact ccattagata gtcacggtgc ctactctggt
    30001 tctgccatgc aatttggcga taacttattc ctattttata caggaaatgt tcgcgatgaa
    30061 aactggatcc gtcacccata ccagatcggt gctttgatgg acaaggaggg taagattaca
    30121 aagattgaca agatcttgat tgaccagcca gcagactcta ctgaccactt ccgcgatcca
    30181 caaattttta actttaaagg tcaatactat gctgtcgtcg gtggacagga cttggagaaa
    30241 aaaggcttcg tccgtctcta caaggctgtc aataacgact acacaaactg gcaagcagtt
    30301 ggcgaccttg actttgctaa cgaccgtact gcctacatga tggaatgtcc taatctggtc
    30361 tttgtagagg aacagcctgt ccttctctac tgtccacaag gattggataa gaaagttcta
    30421 gactacgata atatctttcc aaatatgtat aagattgggg cttcctttga ccctaaaaat
    30481 gccaaaatgg tagatgtgtc tcaacttcaa aacatggatt acggtttcga agcctatgca
    30541 actcaagcct tcaacgctcc tgatgggcgt gctctagcag ttagctggct tggtttgcca
    30601 gatgtttctt acccatctga ccgttttgac caccaaggaa ccttctcttt ggtcaaggaa
    30661 ctcactatca aagacgacaa gctctaccag tatccagtcg ctgctattaa ggaccttcgt
    30721 acttctgaag aagccttctc aaaccgttcc caaaccaaga acacttacga acttgaactc
    30781 aacttggaag ctaatagcca gagcgagatt gtcttacttg ctgataaaga aggtaaggga
    30841 ctttcaatca actttgacct tgtaaacggt caagtgacag tggatcgtag ccaggctgga
    30901 gagcagtatg cccaagaatt tgggataact cgttcttgcc ctatcgagaa tcaggctact
    30961 actgctacaa tcttcatcga taactctgtc tttgaaattt tcatcaataa aggagaaaaa
    31021 gtattttctg gtcgtgtctt cccacatgcg gaccaaaatg gtatcctgat caaatctgga
    31081 aacccaactg gaacttacta tgaattagat tatggtcgca aaactaactg atgtcgccaa
    31141 acttgcaggc gtcagtccta ctaccgtttc tcgggttatc aataaaaaag gatatctatc
    31201 tgagaaaacc atccaaaaag tcaatgaagc catgcgagaa ttgggctata aacccaacaa
    31261 cctggctcgt agtctgcaag gaaaaccagc taagttaatc ggcttgattt tccccaatat
    31321 ttccaatgtt ttctatgcag aattgattga taaattggaa caccaactct tcaaaaatgg
    31381 ttacaagacc atcatctgca acagtgaaca tgattctgag aaggaacgtg aatacatcga
    31441 aatgttggaa gccaatcagg tggacggcat catttctggt agtcacaacc taggaatcga
    31501 agactacaat cgtgtgacag cgccgattat ttcctttgac cgaaacctat cgccagacat
    31561 ccctgtcgtc tcctctgaca actatgctgg tggggttctt gctgcccaaa ccttggtcaa
    31621 gacaggtgcc cagtctatca tcatgattac agggaatgac aattccaatt cgccaaccgg
    31681 actgcgccac gctggttttg catccgtact cccaaaagct cctattatca atgtttccag
    31741 tgacttttct cccgtcagaa aagaaatgga aatcaagaat atcttgaccc gggaaaaacc
    31801 agatgccatt tttgcttcgg atgatttgac agctattctg gtcattaaaa tcgctcaaga
    31861 attgggcatt tctgtcccaa aagagctcaa ggtcatcggc tatgatggga cctactttat
    31921 cgaaaattac taccctcaat tggctactat caagcaacct ttggaagaga ttgcttgtct
    31981 cactattgat cttctcttgc aaaagattga aggcaaggaa gtcgccacaa ctggttactt
    32041 cttaccagtt acgctattac caggaaaaag tatttaaaca caagaaaact cagaccgatt
    32101 cgtctgagtt tttatgatct taaattttcg agatagcgct gggctgtctc taggttaaag
    32161 gttttatctg agatgaggcg ctctactagg ggagcaactt cagattcact agccccagct
    32221 aggagagcta gggatttggc ctgtagtttc atgtggcctt gctggatgcc cgtacttacc
    32281 aaggctttga gggctgcaaa attttgagca agaccgatgg acacgataat ctgggctaat
    32341 tctctggcag aaggatttcc tagtagatca tgactgagag ctacacgtgg gttgaggccg
    32401 atagagccac ccttagtcgc tacaggcatg ggcagggtca tctcaccgac caattcttct
    32461 ctttcaaggt ccagcgtcca gcagctaaga ccttgatagc gtccatctcg actggcaaag
    32521 gcatgggccc cagcttcgat ggcacgccag tcattaccag tggcaatcaa aatcgcatca
    32581 ataccattaa aaattccttt attatgagta gcagctcggt aaggatcagc ctgcgcaaac
    32641 tgactagcca acgcaatttt ctccgcaatc tctcgtcctt gatccttttg gcggctcaag
    32701 tagcgaaagg cgatgcgaca gcttgcagtc accagagaat cagtcgcgta gttggacagg
    32761 attcccatga gactctgtcc ctgactgagt tcttctaaga ctggtttcaa ggcttccagc
    32821 atggtgttga gcatattggc acccatggct tcctgggtat cgacatgaat ataaacaacg
    32881 agaaagtctg gttcgccttt tatctgctcg acatgcagat cacgcgcccc acccccacgt
    32941 ttaacgatag aaggataggc ttgattggca agctccaaga gctccgcttt cttgctggca
    33001 atcttctctt gcgctagttt aggattagca acttgataaa gggctacctg cccaatcatc
    33061 tggcgctgat ggacttgtgc agtaaaacca cctgcacgct tgatgatttt gctggcatag
    33121 ctggccgccg caaccacaga gggttcttct gtcacatagg gaacggtgta ttcctgaccg
    33181 ttgacaagta cctccggaac cagcgaataa ggcagagaaa aagttcccac cacattctca
    33241 ctcagctggt ctgccacagt cacactcatc tgttcatcct tctccagact agcttgtctc
    33301 tcaggactaa ggagcgcctg agcttttagc agctcgaggc gctcttggta tgatttttta
    33361 gaaaatccat tccaacttat cttcattatt tttcaacctt gctataacgg cgttggtggt
    33421 caagaatttc aaccaaggca aaatcttgat tttcatagcc agcaaactgg gcagagtttg
    33481 tttcatccaa gtttacttcc tcaaaaaaga ccttttcata gtctgcaacg gatagggcag
    33541 ttcgttggtt gagcttgttc aagcggtctt tatccaaata agcttcatat ccttcaacca
    33601 attcaccact gaagaactca gccacagctc cacttccgta actataaagg gcgattttat
    33661 ccccagcttt caagctatct gtattttcca agagagacaa aagtccaagg aaaagtgaac
    33721 ctgtgtagat attccccacc ttttgactgt agagaataga ctggtcaaaa tgcttttgta
    33781 agaggtcttt tttctcttga ggcaggctct tatccatgat ttttttcaag ccttttagcg
    33841 ctaatttagg ataaggcaag tggaaacaaa cagccgcaaa atcatccaaa gtaagctggt
    33901 agcgtttttg atattcaagc caagtcgttt tcaaactatc caagtattgt tgggtagaat
    33961 agacaccatt tacataagga gttgtcgagt aatttggtcg ccagaaatcc atgatgtcac
    34021 gggtctgagc tacattgtca ttattaaagg ccatcatgcg tggattttgt gtaatcaaca
    34081 tagctacact tccagcacct tgagttggtt ctcccggagt ttcaatacca tatttggcaa
    34141 tatcactggc aatgaccaag accttggact ccggagaatt ttccacatgc aatttggcat
    34201 aatggagggc agctgtcgcc ccatagcagg cttctttaat ctcgaaacta cgagcaaagg
    34261 gctggatgcc cagcaagcca tgcacaaaga cggccgcagc cttactctgg tcaattcctg
    34321 actcggtagc cacaatgacc atgtcaactt cttgtctttc ttgctcagtt aaaatagagt
    34381 cactagcact ggccgccaag gtcacgatgt cctcagttag gggcgcaata ctcaattcct
    34441 tgagtaagag tcctttactt aatttttcag ggtcaattcc cctcgcttct gctaagtctt
    34501 gtaatttcaa gacatattga ctggtcgcaa aaccaatctt atcaataccg attgtcatat
    34561 ttacctctgt tttatcattc atgtaaaaaa tcgttctata ctattttatc acaaatggca
    34621 gtaaaagaga gaaaaaagac ttgattcacc aaatcaagcc tcttattggt catcatttta
    34681 aagaatgatt agttgctaga gagttcaccg atataagtag ctttataagc tccattcaca
    34741 gttatcagct cctggaggat caaatttcct gagtaaatcc ttcccatctc atctacaaat
    34801 ttttgataaa actgactgat cggaatttct ctgacatcct tatcaaatgt cttatcaagt
    34861 gttttactaa ccttctcagc aatcaattga tgctcttgcc atccactttg aaactctgag
    34921 cccgaactag aaaccatgac tgggataaac aacaaggtca gtagatttac agacaataag
    34981 gaaagtagta gacttcctgc aa
//
LOCUS       DBERCW010000022        33748 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.022, whole genome shotgun sequence.
ACCESSION   DBERCW010000022 DBERCW010000000
VERSION     DBERCW010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.022"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..4099
                     /locus_tag="ACL72M_001278"
     CDS             <1..4099
                     /locus_tag="ACL72M_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS0716402.1"
                     /translation="RGLTGAQGAKGEKGDQGERGLTGAQGAKGEKGDQGEQGLQGRDG
                     EQGPKGEDGKNPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEA
                     DKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDN
                     NNGTHTITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSY
                     TAGKDELVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFV
                     KKGNTWEPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGAKGADGAAGRDGRDGRD
                     GKDVLNGKVNPEENQGKDGDKYVNTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAKG
                     EKGDRGERGLTGAQGAKGADGAAGRDGRDGRDGKDVLNGKVNPEANQGKDGDKYVNTE
                     TGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKD
                     PVTVNVKDGENGLNGKTPKVDLLRVQGQNGNPPHTIVTFYTDENNDGKYTPGTDELLG
                     SEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGK
                     SPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQDGQTPTITTQR
                     GQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAATP
                     TRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTI
                     TVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGK
                     TPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNP
                     DGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVT
                     ITDEQNGTHKISVLNGDGTTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSETT
                     VRDGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEV
                     PVKPVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNAN
                     PVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            complement(4336..4884)
                     /locus_tag="ACL72M_001279"
     CDS             complement(4336..4884)
                     /locus_tag="ACL72M_001279"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS0716403.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5205..5693
                     /locus_tag="ACL72M_001280"
     CDS             5205..5693
                     /locus_tag="ACL72M_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGS0716404.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            5690..6877
                     /locus_tag="ACL72M_001281"
     CDS             5690..6877
                     /locus_tag="ACL72M_001281"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0716405.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            6870..7235
                     /locus_tag="ACL72M_001282"
     CDS             6870..7235
                     /locus_tag="ACL72M_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0716406.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7251..8597
                     /gene="asnS"
                     /locus_tag="ACL72M_001283"
     CDS             7251..8597
                     /gene="asnS"
                     /locus_tag="ACL72M_001283"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGS0716407.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            8750..9040
                     /gene="rpsF"
                     /locus_tag="ACL72M_001284"
     CDS             8750..9040
                     /gene="rpsF"
                     /locus_tag="ACL72M_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGS0716408.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9052..9522
                     /gene="ssbA"
                     /locus_tag="ACL72M_001285"
     CDS             9052..9522
                     /gene="ssbA"
                     /locus_tag="ACL72M_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGS0716409.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            9554..9793
                     /gene="rpsR"
                     /locus_tag="ACL72M_001286"
     CDS             9554..9793
                     /gene="rpsR"
                     /locus_tag="ACL72M_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGS0716410.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10088..11488
                     /locus_tag="ACL72M_001287"
     CDS             10088..11488
                     /locus_tag="ACL72M_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGS0716411.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            11490..11849
                     /locus_tag="ACL72M_001288"
     CDS             11490..11849
                     /locus_tag="ACL72M_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGS0716412.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            11903..12652
                     /locus_tag="ACL72M_001289"
     CDS             11903..12652
                     /locus_tag="ACL72M_001289"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGS0716413.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            12642..12941
                     /locus_tag="ACL72M_001290"
     CDS             12642..12941
                     /locus_tag="ACL72M_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGS0716414.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13012..13947
                     /locus_tag="ACL72M_001291"
     CDS             13012..13947
                     /locus_tag="ACL72M_001291"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGS0716415.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14033..14545
                     /locus_tag="ACL72M_001292"
     CDS             14033..14545
                     /locus_tag="ACL72M_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGS0716416.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            14529..15178
                     /locus_tag="ACL72M_001293"
                     /pseudo
     CDS             14529..15178
                     /locus_tag="ACL72M_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15279..15476
                     /locus_tag="ACL72M_001294"
     CDS             15279..15476
                     /locus_tag="ACL72M_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS0716417.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(15519..16964)
                     /locus_tag="ACL72M_001295"
     CDS             complement(15519..16964)
                     /locus_tag="ACL72M_001295"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGS0716418.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVKDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17070..18692
                     /locus_tag="ACL72M_001296"
     CDS             17070..18692
                     /locus_tag="ACL72M_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGS0716419.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLCSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            18896..20854
                     /locus_tag="ACL72M_001297"
     CDS             18896..20854
                     /locus_tag="ACL72M_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0716420.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSVQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21026..21259
                     /locus_tag="ACL72M_001298"
     CDS             21026..21259
                     /locus_tag="ACL72M_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGS0716421.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            21277..21798
                     /locus_tag="ACL72M_001299"
                     /pseudo
     CDS             21277..21798
                     /locus_tag="ACL72M_001299"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
     gene            21985..22707
                     /locus_tag="ACL72M_001300"
     CDS             21985..22707
                     /locus_tag="ACL72M_001300"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716422.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARAYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            22865..23959
                     /locus_tag="ACL72M_001301"
     CDS             22865..23959
                     /locus_tag="ACL72M_001301"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS0716423.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            23967..25133
                     /locus_tag="ACL72M_001302"
     CDS             23967..25133
                     /locus_tag="ACL72M_001302"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGS0716424.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            25226..28324
                     /locus_tag="ACL72M_001303"
     CDS             25226..28324
                     /locus_tag="ACL72M_001303"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0716425.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWIPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28372..28989
                     /locus_tag="ACL72M_001304"
     CDS             28372..28989
                     /locus_tag="ACL72M_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS0716426.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29000..30334
                     /gene="murC"
                     /locus_tag="ACL72M_001305"
     CDS             29000..30334
                     /gene="murC"
                     /locus_tag="ACL72M_001305"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGS0716427.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30344..30808
                     /locus_tag="ACL72M_001306"
     CDS             30344..30808
                     /locus_tag="ACL72M_001306"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716428.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            30805..31299
                     /locus_tag="ACL72M_001307"
     CDS             30805..31299
                     /locus_tag="ACL72M_001307"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716429.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31380..33035
                     /gene="mltG"
                     /locus_tag="ACL72M_001308"
     CDS             31380..33035
                     /gene="mltG"
                     /locus_tag="ACL72M_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGS0716430.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33106..33588
                     /gene="greA"
                     /locus_tag="ACL72M_001309"
     CDS             33106..33588
                     /gene="greA"
                     /locus_tag="ACL72M_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGS0716431.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10471 a         6272 c         7631 g         9374 t
ORIGIN      
        1 acgcggtcta accggagcac aaggtgccaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctaaccgga gcacaaggtg ctaaaggtga aaaaggggac caaggtgaac aaggtcttca
      121 agggcgtgat ggtgaacaag gaccaaaagg agaagatggg aaaaacccaa cagttaaagt
      181 aactgatggt caagatggaa cgcatacaat tacaattaac gatggtaaag gtggtataac
      241 tactacagta gtaagagatg gatttgatgg tgcaagccct cttgtttcta ctcatagaaa
      301 tgaagcagat aaaacaacaa ctgttatttt ctattatgat ctaaatgata ataatcaatt
      361 tgatgaagga gatacaaaac ttaaagaagt tgttatcgca gatggaaaac aaggaccaaa
      421 aggtgacaaa ggtgataacg gaaaagatgg attcacacca gaagtaacag ttacagataa
      481 caataacgga acacacacca tcacaatcac acaaccagac aacagaccat cattaacaac
      541 aatcgttaaa aacggtgaag atggaaaaac accaaaagtc aaagcagaac gagatgatgc
      601 gaagaaacaa acaacattaa cattctacat tgacaaagat ggagatggaa gttacacagc
      661 aggaaaagac gagttagttc aaacaacagt agttaaagac ggacaagacg gagctgcagg
      721 agcatctgga cgtgatggaa aagaagtatt aaacggaaaa gtagacccaa caacagaagg
      781 taaagatgga gacacattcg taaatacaca aacaggagat gtattcgtta agaaaggtaa
      841 cacttgggaa ccagcaggaa acatcaaagg accgaaaggt gacaaaggtg cagatggtgc
      901 caagggtgaa aaaggagccc aaggagaacg cggcctgact ggagcgcaag gagctaaagg
      961 tgcggatgga gcagcaggtc gtgacggacg tgatggacgt gacggtaaag acgtgttgaa
     1021 cggcaaagtt aacccagaag aaaatcaagg taaagacggc gataaatacg ttaatacaga
     1081 aacaggtgat gtctatgtta aaaacaatgg aaactgggat aaagagggca acatcaaagg
     1141 acctaaaggt gacaaaggtg cagatggtgc caaaggcgaa aaaggagacc gaggcgaacg
     1201 cggcctgact ggagcgcaag gagctaaagg tgcggatgga gcagcaggtc gtgacggacg
     1261 tgatggacgt gacggtaaag acgtgttgaa cggcaaagtt aacccagaag caaatcaagg
     1321 taaagacggt gataaatacg tcaatacaga aacaggcgac gtcttcgtta agaataacgg
     1381 caactgggat aaagagggca acatcaaggg acctaaaggg gacaaaggtg aacgcggaga
     1441 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     1501 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     1561 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggacaaa acggaaatcc
     1621 acctcataca attgtgacat tctatacaga tgaaaacaat gatggcaaat atacaccagg
     1681 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggtg cggacggacg
     1741 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     1801 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     1861 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     1921 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     1981 tggtgctaag ggagaaactg gtgcaaccgg tcaagatgga caaactccta caatcactac
     2041 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     2101 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     2161 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     2221 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     2281 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     2341 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     2401 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     2461 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     2521 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     2581 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     2641 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     2701 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     2761 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     2821 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     2881 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     2941 tcataagatc tctgttctaa atggtgacgg aacaactact gaaacaatca ttaaagatgg
     3001 taaatcacca gtagcaacag ttagagataa ccaagatggt acttacacta ttcgtgtgga
     3061 aaacggtaat ggtactgttt ctgaaaccac agttcgtgac ggtaaatcac caactgctaa
     3121 ggttgtggat aatggagatg gaactcacac tatcacagtt gtgaactcag acggaacaac
     3181 tacaacaact acagttcgtg atggtagaga accaaaactt gaagttattg ataacaacga
     3241 tggttcacac actattaaag tgacaggtgc tgatggtaaa ggaacgacaa ctacaatctt
     3301 tgatggtaaa tcaccaaaag cgaacatcgt tgataacgga gatggaactc atacattaac
     3361 aatcgtagat tctgatggtc gtgaatacaa atctattatc aaagatggta aagacggcaa
     3421 agatagcgtt tcaccaactg taactgttaa aaataataac gatggaactc acgttgttac
     3481 aatcactaat ccagatggaa gtaagacaga aatggtgatt aaagacggta aagatggtaa
     3541 atcaccaaaa gtttctgttg aagataatgg tgatggtagt catacaatca caatcatcaa
     3601 ttctgatgga actgtgacaa aaacagttat taaagatggc aaagatggta gagatggacg
     3661 tgatggtcga gacggcaaag acggtaaaga cggtaaagat ggaaaatgtg gatgccaaga
     3721 caaaccagta acaccatcaa atgacaaacc agttcctcca acaccaaatg tgccgacacc
     3781 agaagtaccg gttaaacctg tgccagcgca accaacacca aatgtaccga caccagaagt
     3841 gccagtacaa ccaactccag ctgttccaac accagaagta ccggttaaac cagtaccagc
     3901 ggttccagaa caaccagtag taccaacacc ggctcaacca gcaactccag taaatgctaa
     3961 tccagtagca ccaactacag gtaaagaaaa ccgtggggac aaattacctg aaactggaag
     4021 ccaatctgat tatatctctg ttcttttagg tagcggtatt ctattgagcc tatatgtagg
     4081 acgaagaaaa gaagattaat cagccaaaag cagtcactaa tttctcgaaa gaagatgata
     4141 agtgatagat ctcgaatgaa agaatattct tagaatgatt ttcctatgat ggaaaagact
     4201 gctaaaaacc ttgagtggta acgctcaagg tttttttgga tggctgatgt ttgtctgaaa
     4261 atcttgattg agaaataaaa agccacccta ttaggtggct ataattgatt tagactttct
     4321 aaaattttct attttttact gaatcgcttc gaccaagtct tgagcttgtt tttcaagtga
     4381 gtttaggact gtttcttcaa gaaccaattt tccgtctgcc caggcagagt cattaacacg
     4441 tgcagcagtg aaatcaccaa cgccttgtgt acggataaat ggcaagaggt ctttgtagat
     4501 agcgaaaagt tgatcgtgcc ctgcattggc tacagatgat actgtgacaa acttgtcttg
     4561 aagggcagaa acgccacgtg tatcagacaa gtcaagggca cgagatagcc agtcaagcaa
     4621 gtttttcact gtaccaggga tagagaagtt gtagactgga gagaaaatcc agatagcatc
     4681 cgcaacgaga actgcttcac gagcagcagc tacagctgga tgtgttggaa cttccaaatc
     4741 ttggctgaag agaggaaggg ctgaataatc aaggtagcta acttccgctt taccagcaag
     4801 tgctttctca gcttcgagcg ccatttggtg gttgaaagaa ccttgacgta gtgatccgac
     4861 gataaataat acttttttag acatgatgtg tctccttttt cttaaaattt cgagaactct
     4921 ctcgttgtta taaaatatat tacaacaaaa caaaagaact tgcaagaaat ttgctcagag
     4981 tttatttgaa aattgtaaaa tttcggaaac tctaatcatt tgtgactgaa aaagtaagaa
     5041 ctgtttcact ttcaaaatcg gttttgtttg aagggagaaa tagaattggt tgctcaaagc
     5101 acagctttga ggttgcagat aaagctgacg tggtttgaag agattttcga agagtattct
     5161 tatattcact tgtaataaag cttaatagat ggtaaaatag acgagtgaaa aaaagacaaa
     5221 acaaagcaaa aaataatcta ctgtggcagt atggtctagg gatgacgatt ttgtttgtgg
     5281 ttatcagtgg ttcctttctg tatatggttt ctcttagcat gaaaccctat caaacagcta
     5341 aaagtgaagg agaaaaatta gctcagcagt atgcaggatt agagcaggtc gatcaggttg
     5401 atttatacaa tggcttggaa tcttattaca gcgttcttgg tcgtaataaa cagcaagaag
     5461 cgcttgctgt cctgattggt aaagatgacc ataagattta cgtttatcag ctaaatcagg
     5521 gtgtttcaca agaaaaagca gaaacggttt ctaaggaaaa gggagctggc gagattgaca
     5581 agataacctt tggccgttat caagataagc caatctggga agttaagtca ggatctgatt
     5641 tttatctagt agattttgaa acaggagcat tggtcaacaa ggagggccta tgaaactatc
     5701 caaccgtgtt ttagaaatgg aagaaagtgt gactttggct gctggagccc gtgccaaagc
     5761 actgaaggct gagggtagag atattttgtc tctaaccttg ggtgagccag atttcactac
     5821 tcccaaaaat atccaagatg ccgccattgc atcgattcga gatgggcgtg cttcttttta
     5881 tacagtaacc tcaggtctgc cagagcttaa ggcggcggtc aatagctact ttgagcgctt
     5941 ttacggctat tctgtagcgt caaatcaagt gacagtcgct gcgggagcca aatattctct
     6001 ctataccttc tttatggctg tggtcaatcc aggtgatgaa gtcatcatcc caaccccata
     6061 ctgggttagc tatggagatc aggtcaagat ggcagaaggc gttcccgtct ttgtttctac
     6121 taaggaagac aatcacttta aggtgaccgt agatcagtta gaagcagctc gcactgacaa
     6181 gaccaaggtt ttggtgctga attcgccatc taatcccaca ggtatgattt acacccgtga
     6241 ggaactcttg gcaattggaa actgggctgt agaaaatgat attctcatcc tagcagatga
     6301 tatctatggc cgcttggttt ataatggtca tgagttcaca ccgatttcta gcctatcgga
     6361 agcgattcgc aagcaaacag tggtcatcaa tggtgtgtct aaaacctatg ccatgactgg
     6421 ttggcggatt ggttatgccg ttggagaagc agatattatc gctgccatgt ccaagattgc
     6481 aggtcaaaca acttcgaatc cgtcagcagt agcccaatat gcagcagttg aggctctatc
     6541 aggtgagcaa gatactgtag aaagcatgcg tcaggccttt gaggaacgtc ttaataccat
     6601 ctatcccctc cttgcagagg taccaggatt tgaagtggtc aaaccgcaag gggccttcta
     6661 tctcttccca aatgtcaaaa aggccatgga gatgaaaggc tacacggatg tgacagactt
     6721 tacaactgct atcttagaag aagccgaagt ggccttggta acaggagctg gatttggagc
     6781 accagaaaat gtccgcctca gctatgcgac agacctagac acgcttaaag aagcagtcga
     6841 acgcttgaaa gcatttatgg gtagtgagaa tgattgatca ttttgagatt aaggtaaagg
     6901 atttacaaat ttcagaagga ttttatagga gttttctcgc tcctttggac tataaattgg
     6961 cttttaagac tagttctcta attagttttc tatccccgaa cagccctcat cctggtggtg
     7021 atttttggct gactcaggga acacaagatc ctgttcattt tgctttttta gcagaaaata
     7081 aggaagaagt tcaggcttgt tatgaggctg gcttagaggc aggtgggcga gacaatgggg
     7141 ctcctggtta tcgaagtgag catccgattt actatgctgc ttttatgatt gacctggatg
     7201 ggaacaatat agaggtggtt tgccataaag aataaaaaag aaaaggaaaa ataatgacaa
     7261 aacgtgtaac gattattgac gtaaaagact atgttggtca ggaagtgacg attggcgctt
     7321 gggttgccaa caaatcagga aaaggaaaaa tcgctttctt acaattgcgt gatggaacag
     7381 ccttctttca aggtgtggct tttaaaccaa actttgtcga aaaatttggt gaagaagtgg
     7441 gacttgagaa gtttgatgtt atcaaacgct tgagccaaga aacgtctgtt tatgtgacag
     7501 gtattgtcaa agaggacgaa cgttctaaat ttggctatga gttggacatc acagacatcg
     7561 aagtgatcgg tgaatctcaa gactacccaa tcacaccaaa agaacacgga acagactttt
     7621 tgatggataa ccgtcacttg tggctacgct ctcgtaagca agtagctgtg ttgcaaatcc
     7681 gtaacgctat tatctatgca acttatgagt tctttgacaa gaacggtttt atgaagtttg
     7741 acagcccaat tctttcagga aatgcggcag aagattctac agaactcttt gaaactgact
     7801 acttcggaac gccagcctac ttgagccaat caggtcagct ttacctagaa gcaggggcta
     7861 tggctcttgg tcgtgtcttt gactttggtc cagttttccg tgctgaaaaa tcaaaaacac
     7921 gccgtcactt gactgagttc tggatgatgg atgctgagta ctcatacttg acacatgatg
     7981 agtcgcttga cttgcaagaa gcttatgtga aagctcttct acaaggtgtt cttgaccgcg
     8041 cgcctcaagc cttggaaacc ttggaacgtg atacagaact cttgaaacgc tacattgcag
     8101 agccattcaa acgtatcact tacgatcaag ccattgacct cttgcaagag catgaaaatg
     8161 atgaagatgc tgactacgag catcttgagc atggtgatga ctttgggtca ccacacgaaa
     8221 cttggatttc aaaccacttt ggtgtgccaa catttgtcat gaactatcca gcagccatca
     8281 aggccttcta catgaaacca gttcctggaa atccagagcg cgtgctttgt gcagacttgc
     8341 ttgctccaga aggctatgga gaaattatcg gtgggtctat gcgtgaggaa gattacgatg
     8401 cccttgtcgc taagatggat gaacttggca tggatcgtac agaatatgaa ttctaccttg
     8461 accttcgtaa atacggtaca gttccacacg gaggatttgg tatcggtatc gaacgtatgg
     8521 taaccttcgc agcaggaaca aaacatatcc gtgaagctat tccattccca cgtatgttgc
     8581 accgtatcaa accataagaa caggaaaacg cccatgtggc gttttttcga attctagtgt
     8641 ttttacttgc gtaaaaaaat tttttctagt ataatagttt attgtgagcg aacctcactt
     8701 accccttgca aagtcttggg gtcattagac caaaaggagg aacatatcaa tggctaaata
     8761 cgaaattctt tatatcattc gtccaaacat tgaagaagaa gctaaaaacg ctttggtagc
     8821 acgttttgac tctattttga ctgacaacgg tgcaactgtt gttgaatcaa aaacttggga
     8881 aaaacgtcgt cttgcatacg aaatccaaga tttccgtgaa ggactttacc acatcgttaa
     8941 cgttgaagca aatgacgatg cagctcttaa agagtttgac cgtctttcaa aaatcaacgc
     9001 tgacattctt cgtcacatga tcgtcaaaat tgacgcgtaa gaaggtaaac tatgattaac
     9061 aatgttgtac ttgtagggcg tatgacacgt gacgctgagt tgcgttatac cccatcaaat
     9121 gtagcagttg cgacttttac tcttgcagta aaccgtacat ttaagagtca aaatggtgaa
     9181 cgtgaggctg attttatcaa tgtcgttatg tggcgccaac aggctgaaaa tcttgctaac
     9241 tgggctaaaa aaggctcact tatcggggtg acaggtcgta tccagactcg tagttacgat
     9301 aaccagcaag gacaacgtgt ctacgtgaca gaggtcgtgg ctgagaattt ccaaatgttg
     9361 gaaagccgta gtgtgcgtga gggccacaca ggtggagctt actctgcacc aactgcaaac
     9421 tattcagcac ctacaaattc agtaccagac ttttcacgta atgaaaatcc atttggagca
     9481 acaaacccat tggatatttc agatgatgat ttaccattct aatggacaac taaacttata
     9541 aaggagaaaa aacatggctc aacaacgtcg tggcggattc aaacgccgta aaaaagttga
     9601 ttacatcgca gcaaacaaaa ttgaatatgt tgattacaaa gatactgagc ttcttagccg
     9661 tttcgtttca gaacgtggga aaatccttcc tcgtcgtgta acaggaactt cagctaaaaa
     9721 ccaacgtaaa gtaacaacag ctatcaaacg cgctcgcgta atggctttga tgcctttcgt
     9781 aaacgaagat taaagaaaag acccggttgg gtctcttttt catgagcttg aaaacaagaa
     9841 agcgaattaa gaccccaacg ggtctttttt cacaagcttt gaaatgagag agcgagttag
     9901 gctcagtggc tcccttttta cgagtttgaa aacaagagaa cacattaaaa gcacgatgga
     9961 gctttttcat aaatatgtct tttttctcat ccaagaaatt aaaataaaaa tgataaactt
    10021 tttgaaaata ggggatttgc ctactttatg atataatgga aagagttaga ttgaaagagg
    10081 tagtgagatg gacgcgaaat taagatacaa ggcaaagaag atcaagattg tcttttttga
    10141 tattgatgat acattgcgga attcaaagac agggtttatt ccaactacaa ttcccactgt
    10201 ttttaaacag ttgcgtgaaa aaggaatttt aacaggaatc gcctctggac gtggcatttt
    10261 tggtgttgtt ccagagattc gtgatctcaa gcctgacttt tttgtaactt tgaatggagc
    10321 ttatatcgaa gataaaaaag gtcaggtcat ttatcagcat cagattgaaa agtcagatgt
    10381 tgaggagtat atctcttggg ctaagcaaga aggaattgag tatggcttgg ttgggagtca
    10441 tgatgccaag ttgtcgactc gcaccgatat gatgagtgaa gctatcaatc caatttatcc
    10501 cgacttagat gtagatcccg atttccatga aaaagaagat atctatcaga tgtggacttt
    10561 tgaagataag ggagatgact tgcacttgcc tgacagtctc tcagacaaac ttcgcatggt
    10621 tcgttggcat caacattcgt ctgatattgt gccgatttca ggctccaaag cgacgggggt
    10681 ggaaaaggtt gtggaacacc ttggcttgaa accagagaag gtcatggttt ttggagatgg
    10741 tctcaacgac ttggaactct ttgattatgc tggaatcagc gttgccatgg gaatttctca
    10801 tgataaaatc aaagaaaaag cagattatat tacaaaaaca ttagaagaag atggcatttt
    10861 tgatgcctta gaagtatttg gtatggtaga aaaagaattg cattttccac aagtagacat
    10921 tgaaacagta gaaggtcctc ttgcgactat taagaccaat cacggagact tacgtatcaa
    10981 gcttttccct gaacatgctc ctaaaacagt ggctaacttt gtatctcttt caaaagatgg
    11041 ctactatgat ggtgtcattt tccaccgtat tatcaaggac tttatgatcc aaggtggaga
    11101 cccaactgga actggtatgg gtggcgagtc aatctacggc gaatcttttg aggatgaatt
    11161 ctcagaagag ctttacaata tccgtggtgc tctttccatg gcaaatgctg gtccaaatac
    11221 caacggcagc cagttcttta tcgtgcaaaa ccaacaccta ccttattcga agaaagaaat
    11281 tactcgtggt ggttggccag aaccgattgc agaaatctat gccaatcaag gtgggacacc
    11341 tcacctagac cgccgtcaca cggtttttgg tcagttagct gatgaagcat cttacgctgt
    11401 cttggatgcc attgctgctg ttgagacagg agctatggac aagccagttg aagatgttgt
    11461 aattgaaact attgaaatcg aggactaaga tgaaaatcgg tgataagcta aaggggcgta
    11521 ttacagggat tcagccctac ggtgcctttg ttgagttaga gacgggtgat acggggctga
    11581 ttcacatttc agaaattcgg acaggattta ttgaaaatat tcatgaaacc ttgaaagtcg
    11641 atgaagaggt tcaagttcag gtagtggatt tagatgaatt tacggggaaa gccagtcttt
    11701 ctatccgcac tttggaggaa gaaaagtacc agtttcctag acggagacgc ttttcaagcg
    11761 accgctttaa ctacggtttt gctccctttc gacgaatgct accaatctgg actggagaag
    11821 ccctgcacca tttaaaaaag aagaagtagt ttagagtttt atattttttg taatgttaat
    11881 atgaatttgc tataatagga ccatggaaga agaacaatta ttaaaatcag gagagcgcat
    11941 taaccagctc ttttcgacag atatcaaaat cattcaaaat agagaggttt ttagctattc
    12001 ggtggatagt gttctcttat cacgatttcc acgttttcct aagaaggggt tgattgtgga
    12061 tttctgtgct gggaatggag cagtggggct ttttgctagc actcgtactc aagcacagat
    12121 attgtctgtt gagattcagg agcgtttggc ggatatggct gaacgctctg tccgtttgaa
    12181 tggattagag gagcaaatgc aggtcatctg cgatgatttg aaaaatatgc ctgctcacat
    12241 tcaggggagt aaggtggata tgattttgtg taatccaccc tatttcaagg tgaatcctta
    12301 ttctaatctg aacgagagtg aacattatct cttggctcga cacgaaatca cgactaattt
    12361 ggaagaaatc tgtcgtagtg cccagagtat tctcaagtct aatgggcgtt tggccatggt
    12421 tcatcgtcct gatcgacttc tggatatttt ggatacgtta aaacgacata atctagcccc
    12481 taagcgcctg cagtttgttt atccaaaaag agaaaaggaa gccaatatgc ttttgattga
    12541 ggcgatcaag gatggctcaa caagtggctt taaggtctta cctcctttga ttgtccacaa
    12601 tgatgatggc tcttatacgc ccgaaatcga agagatttat tatggatcat aaggcttata
    12661 tgtacgttct ggagtgtcgt gatggatcct actatatagg ctatacgact gatatgagaa
    12721 gacgcctcgc tatccacaat agtgggaagg gagccaaata tacacgagca cgcttgccag
    12781 tcaaacttat ctatgctcaa ggttttgcca gtaaggaaga agccatgtcg gctgaagctc
    12841 ttctcaagcg taagaagagg ccacagaagg aagaattttt atctgaaaat caagatagaa
    12901 atttactcag ttattttgaa gaatcgtggg gagtcctttg actcctctta cctttgtcaa
    12961 aaagcgaaaa aaatgctaca ataaagaaaa taaacaaaat gaggtattat catgtccaag
    13021 attctagtat ttggtcacca aaatccagac tcagatgcca tcggatcatc tgtagctttt
    13081 gcctaccttg caaaagaagc ttacggtttg gatacggaag ctgttgccct tggaactcca
    13141 aatgaagaaa cagcctttgt cttgaactat tttggtgtgg aagcaccacg tgttatcact
    13201 tctgccaaag cagagggggc agagcaagtt atcttgactg accacaatga attccaacaa
    13261 tctgtatcag atatcgctga agtagaagtt tacggtgttg tagaccacca ccgtgtggct
    13321 aactttgaaa ctgcaagccc actttacatg cgtttggagc cagttggatc agcgtcttca
    13381 atcgtttacc gtatgttcaa agaacatggt gtagctgtgc ctaaagagat tgcaggtttg
    13441 atgctttcag gtttgatttc agataccctt cttttgaaat caccaacaac acacccaaca
    13501 gataaaatca ttgctcctga attggctgaa ttggctggtg tgaacttgga agaatatggt
    13561 ttggcaatgt tgaaagctgg taccaacttg gctagcaaat ctgctgaaga attgattgat
    13621 atcgatgcta agacttttga actcaacgga aataatgtcc gtgttgccca agtgaacaca
    13681 gttgacatcg ctgaagtttt ggaacgccaa gcagaaattg aagctgcaat gcaagctgcc
    13741 aacgaatcaa acggctactc tgactttgtc ttgatgatta cagatatcgt caactcaaac
    13801 tcagaaatct tggctcttgg tgccaatatg gacaaggtcg aagcggcttt caacttcaaa
    13861 cttgaaaaca atcatgcctt ccttgctggt gccgtttcac gtaagaaaca agtggtacct
    13921 caattgactg aaagctttaa tgcgtaagat tttgggtgtc agctcaaaat cggaaagtct
    13981 agtttgcctt atatcgaaag gagtttcggc tccttttttc taggagtgaa gtatgttaga
    14041 aaatggcgat ttgatttttg tgagagatgg gtcagacatg ggacaggcca tccagacttc
    14101 cacaggtaac tatagccatg ttgccattta tttggatggg atgatttatc atgctagtgg
    14161 acaggctggt gttgtctgtc aagaaccggc agacttcttt gagtccaatc atttatacga
    14221 cctctatgtt tacccagaaa tggatatcca gtcggtgaag gaaagagctt gcaaacatct
    14281 tggagcaccc tacaatgctt ctttctatcc agatgcacct ggtttctact gctcccagta
    14341 tatagcagaa atcctaccta tttttgaaac tattcctatg aaatttggag atggggagca
    14401 ggagattagt gatttttgga gggagtatta catagaacta ggtctgcctg ttcctctgaa
    14461 ccaagctggt accaatccta gtcagttggc agcatcgcct ctgttacaat gtaaagaaag
    14521 gaatcttcat gattcagatt tttaatccat ctcgtttgac gagacagcca tttttggaga
    14581 attgatccgc tatctggacc agtatgagga tgtgattcta cgggaaatta aggctcaatt
    14641 tccagatgtt gcagttgata aactcatgga agagtatata aaggcaggct tgattctacg
    14701 tgaaaataag cgctattacc tcaattttcc tacgcttgaa tcacttgata gtcttgaact
    14761 ggatcaagag atttttgtca gagaagctag tccggtctat caagccttgt tggagcagag
    14821 ttttgagacg gaattgcgca atcaaatcaa tgcagctatt ttagttgaaa agacggactt
    14881 tgcgcgcatt aaaatgactc tgtccaatta tttttacaag gtcaaacagc agtatccttt
    14941 gacagaaaaa cagcaggagc tctatgacat tttaggagat gttaatcctg agtatgcact
    15001 caagtatatg acggcttttt tgttgaaatt tctcaaaaaa gaccagctta tgcagaaatg
    15061 ccgtgatatc tttgtggaca gtttggttgt cttaggctat attgtgcaaa atgaagatgg
    15121 aaagtatgag ttggctatcg attttgataa ggagagatta actttctact tagcgtgatt
    15181 tcttgtttct gagtacattg tttgactttc cttagtattc ggtataaact atatgtaacc
    15241 ggtaacacat atcggaataa actaaaggag acaatcatat gtcacttgaa aacaaattgg
    15301 aacaagcaac aggcgctgtc aaagaaggtt ttggtaaagt tactggagac agcaagacag
    15361 aacttgaagg agctgttgaa aaaacagttg ctaaggcaaa agacgttgta gaagacgcaa
    15421 aaggtgctgt agaaggtgcc gttgaaggtt tgaaaaacgt ttttactaaa gaataggaaa
    15481 aaatcaaggg tttcattttc ccttgatttt ttctattctt ataaataatt ttctgcgacg
    15541 gctgtatctc ctgggtagga ttctttcttg ccctggatga tttggtaaca atcggctccc
    15601 ttacccgcaa taataactgc atctaattcg tgatttgtga tagccattgc cgccttgatg
    15661 gcttcttggc gatccgcaat cttctcaaca ggatgattga tgtagctact aatttcatct
    15721 gcaatggcca ttgggtcttc atagttaggg tcatcagcag tcagaaagac ttgaatctca
    15781 gggtgttgat tgaggaggag gccaaagtcc ttacgacgac tttctccctt gtttcctgtt
    15841 gatcccagaa ccagagcaat ctttccggtt tgatgagttt caaccacatt gatgagtttt
    15901 ttcagactat ccccattgtg ggcatagtcg atgaagacct tggctccatt tttctgagtg
    15961 aggacttcca tacgaccagg aacgcgggtt gcagcgatgc cttttttgat gtcctcaaga
    16021 cttgctccga gacggagaca agcaagtcca gcagcaactg cattttcttg gttgaagttg
    16081 ccaatgagtt ggatatcata atctccagcg agtttacccg tagctgaaaa gctaaaggct
    16141 ttggaattct cgatttggtt atcaaattgg ctaccataga aatcatggtc ttgatcttta
    16201 acctgttctt tcaagactga gaagtggtcc atgtcactgt taatgatgac tgctcggcta
    16261 ttttccatca agagacgctt gtggtagaaa tagtcttcaa agctagggtg ttcaatcggg
    16321 ccgatatggt ctgggctgat attgaggaaa actcccacat caaaggttag accatagaca
    16381 cgtctgacca gataggattg actggagact tccatgatga ggtgggtacg gtcattttgc
    16441 acagcctgat tcatcatgtc aaagaggtca atactctcag gggttgtcaa cgctgactta
    16501 aagaaagtct cgccatcaag agttgtgttc atggtcgaca acatagcagg tcgatgccct
    16561 tgagataaga tgttataggc gaaataggct gctgttgtct tacccttagt accagtaaag
    16621 gcaaggagtt tgagtttttc ctgtggatta ccatagaact ccatggcaat caaactcatg
    16681 gctttcttta tatcgttcac aatgatgaca gggataccga cttcgtagtc cttttcagct
    16741 acataccaag ctaagccttg tgttatagca gaaagaaggt attctttttt aaaggcagcg
    16801 ccttttgcaa aaaaaagagt gtcttctgtt acttttcggc tgtcgtagct gatgctatca
    16861 aaaacaactt tgctgtagtt gtagtggtaa tgaccttggt caataatttc gcgaaaaagg
    16921 ccatctttct ttaaaatatc taatacagtt tcaattttta tcatactttc tattgtaaac
    16981 cgaaagtcgc aaatttacaa gtaacaagga aaagtttata atggaagata aggagttttt
    17041 cctagttatc aaaattgaat gaggaatcta tgtcgcacga aaacaatcac cagcaggccc
    17101 agatgttacg ggggactgct tggctaacgg ctagtaactt tatcagtcgc ctactcgggg
    17161 ctgtttacat tatcccttgg tacatctgga tgggggctta tgcagctaag gcaaatggtc
    17221 tctttaccat gggttacaat atctatgctt ggttcttgtt ggtttcaaca gcggggattc
    17281 cagttgcggt ggccaagcaa gttgccaagt ataataccat gcgagaagaa gagcatagct
    17341 ttgccctgat tcggagcttc ttaggcttta tgacaggact aggcctggtt tttgctttag
    17401 tcttgtatgt ctttgctcct tggctagcag acttgtctgg cgtgggcaaa gacttgatcc
    17461 caatcatgca aagcttggct tggggagtct tgattttccc gtctatgagt gttatccgag
    17521 gatttttcca agggatgaat aacctcaaac cctatgccat gagccaaatt gctgagcagg
    17581 tcattcgtgt tatctggatg ctcctagcaa cctttatcat tatgaagctc ggttcaggag
    17641 attatctagc agccgttacc caatcaacct ttgctgcctt tgtcggtatg gtagccagtt
    17701 ttgcagtctt gatttatttc cttgcccaag aaggttcact caaaagagtc tttgaaacag
    17761 gagataagat taacagtaag cgtctcttgg ttgataccat taaggaagcc attcctttta
    17821 tcctgacagg gtctgccatc cagctcttcc agattttgga tcagctgacc tttatcaata
    17881 gtatgagctg gtttaccaac tacagcaatg aggacttggt tgtcatgttt tcttatttct
    17941 cagccaatcc taataaaatc acgatgattt tgatttctgt aggggtttcg attgggagtg
    18001 ttggtttgcc acttttgacg gaaaactatg tcaaggggga cttgaaagca gcttctcgtc
    18061 tggttcagga cagtctcacc ctactcttta tgttcttgct accagcaacg gttggagtgg
    18121 ttatggtagg agaacctcta tatacagtct tctatggtaa gccagatagt ttggctctgg
    18181 gcttatttgt ctttgcagtt ttgcagtcta ttattttagg cttgtacatg gtcttgtctc
    18241 caatgcttca ggccatgttc cgcaaccgca aggccgttct ctattttatc tatggttcta
    18301 ttgccaagct agtcttgcaa ctacctacca tcgccctctt ccacagttat ggtcctttga
    18361 tttcaacaac cattgctctc atcattccta acgtcttgat gtatcgggat atttgtaaag
    18421 taactggtgt caagcgcaag gtgattttga agcgaaccat tttaatcagt ttgctgaccc
    18481 tagtcatgtt tctgttaata ggaaccatcc agtggctgtt aggatttttc ttccaaccaa
    18541 gtggacgttt gtgtagcttc ttttatgtag ctcttgtcgg tgccatgggg ggtggacttt
    18601 atatggttat gagtctgcgt acctatttat tagataaggt aataggaaaa gcccaagcag
    18661 atcgcctgcg agcaaaattt aagctttcgt aaggtagcat ttataaataa aaggaataag
    18721 ttgaacaatc ttttaggaga acttgaagct tattcctttt ttagcgtaaa aatagctaaa
    18781 attatatttc aaaaatagaa aatgaggctt ttttcgattt tttggaaaaa atcattgact
    18841 aaacaaacta aacgttgtat aataaaacaa atatttaaag caggaggttc cggaaatgaa
    18901 aaagtctaag agcaaatatc taaccttggc aggtcttgtc ctgggtacag gagttttatt
    18961 gagcgcgtgt ggaaattcta gcacggcgtc aaaaacatac aactatgttt attcaagtga
    19021 tccatctagc ttgaactatc tagcagaaaa ccgcgcagca acatccgata ttgttgcaaa
    19081 tttggtagac gggttattag aaaatgacca atatgggaat attattccat cattagcaga
    19141 ggattggact gtttctcagg acggtttgac ctatacctac aaacttcgta aggatgccaa
    19201 gtggtttact tctgagggag aagaatatgc gcctgtaact gcccaggatt ttgtgacagg
    19261 tttgcaatat gcagctgata aaaaatcaga agccttgtat ctagtgcagg actctgttgc
    19321 tggtttggat gactatatca ctggtaaaac aagcgacttt tcaactgtcg gtgtcaaggc
    19381 acttgatgac caaacggttc aatatacttt ggttaaacca gaactttact ggaattcaaa
    19441 aacacttgca acgatacttt ttcctgttaa tgcagatttc ctgaaatcaa aaggggatga
    19501 ttttgggaag gcggatccat ctagtatttt gtacaatgga cctttcttga tgaaagcact
    19561 tgtctcaaaa tctgctattg aatataagaa aaaccctaat tactgggatg ctaagaatgt
    19621 ctttgtagac gatgtgaaat tgacctacta tgatggtagc gaccaagaat cactggaacg
    19681 taattttaca gctggtgctt atactacggc tcgtcttttt cctaacagct ccagctatga
    19741 agggattaaa gaaaaataca aaaacaatat catctatagt gtgcaaaatt caacttcata
    19801 tttctttaat tttaacctag ataggaagtc ttacaattat acttctaaaa caagtgacat
    19861 tgaaaagaaa tcgacccagg aagcagttct caataaaaac ttccgtcagg ctatcaattt
    19921 tgcttttgac agaacatctt atggggctca gtctgaaggg aaagaaggtg caacaaagat
    19981 tttgcgtaac ctagtggttc ctccaaactt tgtcagtatc aagggaaaag actttggtga
    20041 agttgtagcc tctaagatgg tcaactatgg taaggaatgg caaggtatca actttgcgga
    20101 tggtcaagac ccttactaca atcctgagaa agccaaggct aagtttgcgg aagctaagaa
    20161 agaactcgaa gcaaagggtg ttcaattccc aatccacttg gataagactg tggaagtaac
    20221 agataaagta ggcatacaag gagttagttc tatcaaacaa tcaattgaat ctgttttagg
    20281 ttctgataat gtagtgattg acattcagca attaacatca gatgagtttg acagttcagg
    20341 ctactttgct caaacagctg ctcagaaaga ctatgattta tatcatggcg gttggggacc
    20401 tgattatcaa gacccgtcaa cctatctcga tatttttaat actaatagtg gaggagttct
    20461 acaaaatctt ggactagagc ctggagaagc caatgacaag gctaaggcag ttggactgga
    20521 tgtctatact caaatgttgg aagaagctaa taaagagcaa gatccagcca aacgttatga
    20581 gaaatatgct gatattcaag cttggttgat tgatagttct ttagttcttc caagtgtttc
    20641 gcgtggggga acaccatcat tgagaagaac cgtaccattt gctgctgcct atggtttaac
    20701 cggtacaaaa ggggttgaat catataaata cctcaaagta caagataaga ttgtcacaac
    20761 agacgaatat gcaaaagcca gagaaaaatg gttgaaagaa aaagaagaat ccaataaaaa
    20821 agcccaagaa gaattggcaa aacatgtcaa ataaaatcta attgtagata agtttgtgta
    20881 agaagtcttt gtgcttaaaa acgcataata tcaggtatat aaaatcctag atgttatgcg
    20941 ttttgttata ggaagattta ttagatttta tcctcaaatt gagttattcc cgactttatc
    21001 cgttgaaata ttataaggag tatttatgaa attaaaatta ttaagagtag atactaaggt
    21061 gattatgggg agtttcttac ttgttctgtc tagtctactt gctttgttgc ttccccttat
    21121 cttaaagggt ttaatagatg ggagttctat tgaaaatata ggttccaaag tatttcaatc
    21181 gtttttgatt tttattggtc aagccttgtt ttcttctatt ggttactatc tgtttagtca
    21241 atcgggtgaa aaaagatagc aaaaatcagg aaaaaagtga tagaggggtt gatttatgca
    21301 gagaaatcct tctttgataa gagccaaagt ggggagttga cttctgccat tgtcaatgac
    21361 atgagtgtca ttcgtgagtt tttaattacg actttcccaa atattattct gagtttagtt
    21421 atggtacttg gttccattgt agtcttattt agtcttgatt ggaatctttc tctactttta
    21481 ttcatcactc ttccttgtat gatgtttatt atcttgcccc tttccaatat cagtgaaaag
    21541 tatagtcgtc gtttacagga ggaaatcgga tttttaacag ggcaattgac tgaaaagatt
    21601 caagaacatg aattaattaa gactaaccaa gcagagaaaa gtgtacagga tgttttggat
    21661 aattgtattg aaagggtaca aaacaattca ctgaaatcag atagggttac ttcttttgag
    21721 accccgtttg ctctcttatt tatctttgcg actatagttg tgatgctaac ctatgggggt
    21781 tatcgggtca gcgcaggata tatatctgtg ggaaccttgg tttcgttttt gatttacctc
    21841 tttcaattac ttaatcctat tagtaatata gctaattttg taactattta ttctagtagc
    21901 aagggatctt cagttgcact ggagaacttg cttgcagttc ctaaagaaaa atttgaggga
    21961 ggaaaatcgg tatcaggaca agggttgaat tttaaccatg tctattttgg ttatgatgaa
    22021 aatcgacctg tcttaaagga tattacttgt tcaattttca aggggcaaaa aattgctttt
    22081 gttgggccat ctggatcagg aaaatcaacg attgtgcgtt tgttagagcg gttttataaa
    22141 ccgctttcag gagatattct aatggagcaa tcaagtatat atgattttaa cttaaaagaa
    22201 tggagaagta aaatcgcttg ggtttcacaa aataatgcag tcttatctgg cagtattcgt
    22261 gacaatcttt gtctcggttt gaatcgctta gtaactgatg atgaattgat gaaagtgcta
    22321 gacttagtat cactaggtga tgagattcgc tccatgaaag agggactaga tactgaagtt
    22381 ggtgaacgcg gacgactctt gtcagggggg cgaagccaaa gacttcaaat agctagagcc
    22441 tacttaaaag atgctgaaat tcttatattt gatgaagcca ctgctaatct tgatgcggat
    22501 tctgagtatg cgattatcag tagcctctat tctgtactaa aggagaagac ggttgtgatt
    22561 atagcgcatc gcttgtcaac ggtaaaagat gtggattgta ttttcttctt agaggagggg
    22621 aaaatcactg gctcaggaac tcataaggaa ctactggaaa atcatgagcg ttatgctcgt
    22681 tttgtgcagg agcaaatgat agagtgaagg tgtcttttga gattcaccat tttatagtct
    22741 attaaaggga gcaggaaaaa ctcccttttt atatagtttg aaactataac tagctcttga
    22801 aaagaagaaa atgagttgat gaaaataagt ggtacaatag ttactataga tttggaggaa
    22861 ttgtatgagc aaggaattac acattaacac aattttagca caagcaggga tcaagtctga
    22921 tgaggcaaca ggtgctttgg tgacaccact tcatttttca acgacctatc agcatccaga
    22981 gtttggtcga tctactgggt ttgactatac gcgcactaaa aatccaactc gtagtaaggc
    23041 tgaggaagtc ttggcggcta ttgagtcagc agactatgcc ctagcgacta gctcagggat
    23101 gtcagctatt gtactggcct ttagcgtctt tccagtagga agtaaggtct tggcagtgcg
    23161 tgatctttac ggtggttctt ttcgctggtt taaccaagtg gagcaggaag gtcatttcca
    23221 ttttacctat gccaatacag aagaagagtt gattgccgag ttagaaaagg atgtggatgt
    23281 tctctatatc gaaaccccaa ccaatccctt gatgttggaa tttgatatcg aaaaactagc
    23341 aaaattggct catgctaagg gtgccaaagt ggtggtggac aataccttct atagccctat
    23401 ctaccaacgt ccgattgaag atggagcaga tatcgttctc cattcagcaa ccaagtatct
    23461 agcaggccac aatgatgtct tggctggagt ggttgtgacc aatagtttag aactatacga
    23521 gaagcttttt tacaatctta atacaacagg ggcagtcttg tctccatttg acagctacca
    23581 gttgcttcgt ggtctcaaga ccttgtctct tcgtatggag cgctcaacag ctaacgccca
    23641 agaagtggtt gcctttttga aggattctcc agcagttaag gaagttctct acactggtcg
    23701 tggaggcatg atttccttta aagtagccga tgaaacacgc attcctcata ttttgaacag
    23761 tctcaaggtc ttctcttttg cggaaagttt gggtggagtg gaaagtctta ttacttatcc
    23821 aacgactcaa actcatgctg atattccagc agaagtacgc cattcttatg gtttgacaga
    23881 tgacctcttg cgtttgtcta ttgggattga ggatgctaga gatttgattg cagatttgcg
    23941 ccaagcctta gaaggataag acaaagatgg gaaaatatga ttttacaagc ctgcccaacc
    24001 gtttagggca ccatacctat aaatggaaag aaacagaaac ggatagtgaa gttctaccag
    24061 cttggatagc ggatatggac tttgtagtct tgcctgaaat ccaccaagcc gtgcaaactt
    24121 acgcagacca actggtttat ggttatacct atgccagtga agacttaatt aaggaagttc
    24181 aaaagtggga agctacacaa tacggttaca actttgacaa agaggctctt gtctttatcg
    24241 agggtgtggt accagccatc tcaacagcta ttcaaacctt tacaaaagaa ggcgaggcgg
    24301 ttttaattaa cacgcctgtc tacccaccct ttgctcgcag tgtcaagttg aataatcgta
    24361 gattgattac taattcctta gtggaaaagg atagtctgtt tgagattgac tttgaccaac
    24421 ttgaaaagga tttggtggaa gaggaggtta aactctatgt tctttgcaac cctcacaatc
    24481 ctggtggacg tgtttgggaa aaagaagtgt tggagaagat tggccaactc tgccaaaaac
    24541 acggtgtttt gttagtttcg gatgagattc accaagattt gaccctcttt ggtcacaaac
    24601 accagtcttt caataccatc aatcctgcct tcaaaaattt tgctatcgtc ttgagcagtg
    24661 ccactaaaac atttaatatt gctggaacaa aaaattccta tgcagtcatt gaaaatccta
    24721 agttgagact ggctttccag aaacgcctgt tggccaataa tcagcatgaa atttcaggct
    24781 tgggttattt ggcgacagaa gctgcctatc gatacggtaa agattggcta gaggaactca
    24841 agcaagtctt tgaagaccac atcaattatg tggtggatct atttggaaaa gagactaaaa
    24901 tcaaggtcat gaaaccgcaa ggtacctact tgatttggct tgacttttca gcttatgacc
    24961 tgactgatga aacattgcaa gagttgttga gaaatgaagc caaggttatc ctcaaccgtg
    25021 gtttggattt tggagaggaa ggaagtctcc atgcccgcat caatatagct atgcccaaat
    25081 ctctgttgca agaagtctgt cagcggattg tggctacttt tgccaaatgt taaaaatcca
    25141 gccttctagg agaaaagtct tcctagaagg ctattttcat aggcgaaaat atggtataat
    25201 aaaaagataa ggtaaaggtg aaaatatggc taaattgatt ccggggaaaa ttcgtatcga
    25261 aggtgttgcc ctttatgaaa ctggtaaggt tgatatcatc aaggaaaaga acaatcggct
    25321 ctacgctcgc gttgcagaag aagaactgcg ctatagttta gaggatgatt tgattttttg
    25381 tgcctgtgat ttttttcaaa agaggggcta ctgtgtgcat ttggcagcgc tagagcattt
    25441 tctgaaaaat gatgagcgtg gtcaggaaat cttgtggagt ctggaagaag gtcatgaaga
    25501 aaaagaggcc gttgaaacca aggtgacctt gggtggcaag tttttggatc gaattttatc
    25561 tccaaaatca gaatgcgcct atgagttatc agctgtgggt caggtggaag caggaaccaa
    25621 tcatatcttg tggactctga gaatcggcca aatcaatagc caaaaatact atgtcattcg
    25681 ggatattcca ctttttttaa ggattgtcga gcagagaaag tcgtatatga ttggcaagat
    25741 ttatgaggag tctctttctt gggaagcctt tgatgatgcc agccaagaac ttttgacttt
    25801 cttgcacgga ctaacggagg aagggctggt tccagacctc tttttccaaa accaaggtcg
    25861 gcacctcttt ttccctctga ccttttttga gcagggtgtg aatttactga tggccttgcc
    25921 ccattttcaa tttgaccatc aagtggatag ctaccaaacc ctgctttttc aggatatgca
    25981 tgctgatgcc aatctatttg cctttacagt aacagaatat tcggactatt ttgaaatgga
    26041 aatcagtgag agtcctaggg tcaatgtctt ttatcaagga gcagtacttt tccataaagg
    26101 tcaggtttat tttttaacag accagcagat gcgtcttctc aaggaaatta aagcgttacc
    26161 tgtggatcga caaggaaaga aatacctgca atttgatagc agtgatcgag acaaattggc
    26221 ctcctgtctg actcttttta tccagatggg caccgtttca gctccagaac gtctacaaat
    26281 caaaactttt gcgccctctt tttactttga cagggaagaa gataatcgga ttcgtttaga
    26341 aattcagttt gattatggaa atagacaggt atctagccga caagagctag aagaattacc
    26401 attttcaagt gacgcggact tagaagaaag aattttccaa gtctgtttgg ctgcgggctt
    26461 tgaagccgat tttcaatctt ggcgtcaggc cttaaaagcg gagtctgtct atcatttttt
    26521 tcatgatatc attccagtct ttgaaaaact cgggcatgtt gacctatcag ataaactaga
    26581 agagctttat agcctagcga gtcctcaggt gcagattgcc tccaagggag gtctcttgga
    26641 aatccagttt gattttcaag atattgccca ggaggaaatc gaccaagcca tacaggcctt
    26701 ggttgccaat caggattttt atattgattc gtctaatcaa gtttactttt tcgatgaaga
    26761 aaccaagaaa attcgccaaa atctacagga actggggcaa tttgaattaa aagatgggac
    26821 cttgcaggct cggaaatcct tggcctacag tttagctcat ctctttgaag ggcgagaccg
    26881 tgtttctttt tcacaagaat tccagaatct ggcccaggat ttgacgcatc cagaggactt
    26941 tcctttgcaa gcaactcagg tcaaggctga cttgcgagat tatcaggaaa agggaattgg
    27001 ctggttgcag atgctccatc attatggttt tggtgggatt ttggctgatg atatgggact
    27061 tgggaaaacc cttcagacca ttgctttttt gactagtcaa gtgacaaaag aaagtcgggt
    27121 tttgattctc gctccgtcgg gtttgattta caactgggca gatgagtttc agaaatttgc
    27181 tccacagttg gatgtggctg ttgttcatgg tttgaaagca agtcgtgagg agattcttgc
    27241 cgagagccat caaatctatg tgactagcta tgccaccttc cgtcaggaca gtgagcttta
    27301 tcaggggatg gcctttgact tccttttctt agatgaagct caggtcatga aaaatgccca
    27361 gaccaagatt gcccagacct tgagacaatt tgtggtgccg tcggtctttg ccttgtcagg
    27421 aactccgatt gaaaaccatc tgggtgagtt gtggtctatt tttcaaatcg tcatgcccgg
    27481 acttttgcca agcaagaaag aatttatgaa attgccagca gagcgagtgg ctcagtttat
    27541 caagcctttc gtgatgcgac gcaagaaaga agaagttctg actgaattgc cagacttgat
    27601 tgaggtggtt tataaaaatg aactggaaga ccagcaaaag gctatttacc ttgcccagtt
    27661 acaacagatg cgagaccatc tggctcaagt gtcagaacag gaatttcagc gaagtcgtgt
    27721 ggaaatttta tctggtttga tgcgcttgcg tcaaatatgt gacactcctg ccctgtttat
    27781 ggaagattat cagggagcca gcggcaaact agatagtctc cgagacctac tggtacaggt
    27841 ggcagacggc ggacaccgtg tcttgatttt ctctcagttc aagggaatgt tggaaaaaat
    27901 tgaacaagaa ctgccagact tgggcctgac atcctttaaa attacgggtt caaccccagc
    27961 caaggaaaga caagacatga ccaaggcctt taaccaagga gaaagagatg cctttctgat
    28021 ttccctcaag gctggtgggg tcggtctgaa cctgacaggt gcagatacag tgatcttggt
    28081 tgacctttgg tggattcctg cggtggaagc gcaagccatt ggccgtgccc atcggatggg
    28141 tcaggaagaa acggttgagg tctatcgctt ggtgaccaag ggaaccattg aagaaaaaat
    28201 tcaggaactc caagaacaaa agaaacatct ggtgtcacaa gtattggacg gcacagagtc
    28261 acgtggtagt ctgaccctag cagaaattag agaaattttg ggaatttctg aagccagcac
    28321 ttgaaaaatc aagacaatac gctataatga agtgttgaaa ggaaatagaa aatgaaacaa
    28381 gaacgatttc cattggtgtc agatgacgag gtcatgttga ctgaaatgcc agtcatgaat
    28441 ctctatgatg agtctgatct gatcagtaat atcaagggtg agtatcgaga taaaaattat
    28501 ttagaatggg ctcctattgc tgaagaaaaa ccagtaaaac cgattgaaaa gcaagtaggg
    28561 aaacctaaaa aagctccttt aggggttaaa aaagaaggaa agagctatgc ggaggtggcg
    28621 cgtgaagaag cgcgtgcaga cttgaaaaag aaacgctctg ctaactatct aactcaggat
    28681 ttcagccttg cgagacgtca ttctcagccc agtctagtta gacagggcaa tcaaccgaca
    28741 actcctttcc aaaaggaaaa tcctggtgaa tttgtcaaat atagccaaaa attgacccag
    28801 tctcattata tcttggcgga agaagttcat tctatcccta ccaagaatga agaagtgtca
    28861 gcacctgctc caaagaaaaa caattatgat tttctaaaga agagccaaat ctacaataaa
    28921 aaaagtaaac aaacagaaca agaacgtcgg gttgcccaag agttgaatct gaccagaatg
    28981 acagaatagg ggagaaaaca tgtcaaagac atatcatttt atcggaatta agggatcagg
    29041 gatgagtgcc ttggccttga tgttgtacca gatggggcac aaggttcagg gatcagatgt
    29101 tgaaaagtac tactttaccc aacgcggtct tgagcaggca ggaattacca ttcttccttt
    29161 tgatgaaaag aatctagacg gtgatatgga aattatcgct ggaaatgcct ttcgtccaga
    29221 taacaacgtc gaaattgcct atgcggacca aaatggtatc agctacaaac gttaccatga
    29281 gtttctaggt agctttatgc gtgactttgt tagcatggga gtagcaggag cacatggaaa
    29341 aacttcaacg acaggtatgt tgtctcatgt cttgtctcac attacagata ccagcttctt
    29401 gattggagat gggacaggtc gtggttcggc caatgccaaa tattttgtct ttgaatctga
    29461 cgaatatgag cgtcacttca tgccttacca cccagaatac tctattatca ccaacattga
    29521 ctttgaccat ccagattatt tcacaagtct cgaggatgtt ttcaatgcct ttaacgacta
    29581 tgccaaacaa atcaccaagg gtctttttgt ctatggtgaa gatgctgaat tgcgtaagat
    29641 tacgtctgat gcaccaattt attattatgg ttttgaagct gaaggcaatg actttgtagc
    29701 tagtgatctt cttcgttcaa caactggttc aaccttcacc gttcatttcc gtggacaaaa
    29761 cttggggcaa ttccacattc caacctttgg tcgtcacaat atcatgaatg cgacagccgt
    29821 tattggtctt ctttacacag caggatttga tttgaacttg gtgcgtgagc acttgaaaac
    29881 attttccggt gttaaacgtc gtttcactga gaaaattgtc aatgatacag tgattatcga
    29941 tgactttgcc catcatccaa cagaaattat tgcgaccttg gatgcggctc gtcagaaata
    30001 cccaagcaag gaaattgtag cagtctttca accgcatacc tttacaagaa ccattgcctt
    30061 gttggacgac tttgcccatg ctttaaacca agcagatgct gtttatctag cgcaaattta
    30121 tggctcggct cgtgaagtag atcatggtga cgttaaggta gaagacctag ccaacaaaat
    30181 caacaaaaaa caccaagtga ttactgttga aaatgtttct ccactcctag accatgacaa
    30241 tgctgtttac gtctttatgg gagcaggaga catccaaacc tatgaatact catttgagcg
    30301 tctcttgtct aacttgacaa gcaatgttca ataggatgtt cccatggaaa ttccaattaa
    30361 gatcattcag gcaagcaagt ctgatttgcc tgagataggg gcacttcaga cctcgtcttt
    30421 tccagctgaa aagcagcaac tttcccatat tttagaagaa agtatccgta agtgtgcgga
    30481 tacctttctt ctagctaggg atgaaaatca acttttaggc tatattttat caagtcccca
    30541 gtcagacaat ccgcaatatc taaaagtaca ttctttagtc atcgagtctg accatcagag
    30601 acagggcttg ggaacacttc ttcttgcagc cttgaaagag gtggcagttg agctggatta
    30661 caaagggatt cgtttggaga gtcctgatga gctgctttcc tattttgaaa tgaacggttt
    30721 tgttgatgaa gaagcaactt tgctctatgc aactagccag ggctatagta tgatttggtt
    30781 taatcccttt tatctggagg aacaatgaaa atcagacaag caagattaga agatttggat
    30841 cggattgttg aacttgaatt tgaaaatttt tcggtcgaag aagccattcc tccttctgtc
    30901 tttgaagcac atttgagaga aattcagacc tcttttctgg ttgctgaaaa agaaggaaga
    30961 atcatgggtt atatcgaagg accagttggc ctgcaccgcc atctgcaaga ccagtctttt
    31021 acagaagaaa taaaagacta tagtcatgag cctggtggtt atatctctgt gacctgtctg
    31081 tctattgcca aggaggcaca gggactcgga ctgggtcaga aattgctgac agccttgaaa
    31141 gaagttgctc ttgaagatga gagagatggc attaatctaa cctgtcatga ctatctcatc
    31201 gcctactatg aaaaacatgg atttgtcaac gaaggccagt cccagtcaac ctttgcaggg
    31261 gaaacatggt atgatatggt ctgggaaatg aaaaaataag ttaggaaaag tatcatagat
    31321 tgcttttttt ggacttttaa gatataatat tatggattat caacaaggag gaaaaacttt
    31381 tgagtgaaaa gtcaagagaa gaagagaaat taagctttaa agagcagatt ctgagagatt
    31441 tagaaaaagt aaaaggctat gatgaagttc tgaaagaaga tgaggcagta gttcgcactc
    31501 ctgcaaatga accttcaact gaagaactca tggctgattc cttgtcaacg gtagaggaga
    31561 ttatgagaaa agctcctacc gtgcctactc acccaagtca aggtgtacca gcttctccag
    31621 cagatgagat tcaaagagaa actcctggtg ttccaagtca tccaagtcaa gatgtacctt
    31681 cttctccagc ggaagaaagt ggatcaagac caggtccagg tcctgttaga cctaagaaac
    31741 ttgaaagaga atacaatgaa accccaacaa gggtagctgt ttcctatacg acggcagaga
    31801 aaaaagcaga acaagcaggt ccagaaacac ctacgcctgc tacagaaaca gtggatatca
    31861 tcagagatac atcacgtcgt agccgtagag aaggagcaaa acccgttaag cctaagaaag
    31921 agaagaagtc acatgtgaaa gcttttgtga tttcattcct tgtattcctt gccttgctct
    31981 cagcaggtgg ttactttggt taccagtacg tgctagattc cttattacct atcgatgcta
    32041 attctaagaa atatgtgacg gttggaattc cagaaggttc aaacgttcaa gaaatcggta
    32101 cgacgcttga aaaagctggt ttggtaaagc atggtctgat ttttagtttt tatgccaagt
    32161 ataaaaatta taccgacttg aaagcaggtt actacaattt gcaaaagagt atgagtacag
    32221 aagacttact caaagagttg caaaaaggtg gaacagatga accgcaagaa cctgtacttg
    32281 cgactttgac aattccagaa ggttatacct tggatcagat tgctcaagct gtgggtcaat
    32341 tgcaaggtga cttcaaagag tctttgacag cggagacttt cttggctaaa gttcaagatg
    32401 agacgtttat cagtcaagca gtagcgaaat atcctacttt actggaaagt ttgcctgtaa
    32461 aagacagcgg tgcgcgttat cgtttggaag gatacctttt cccagctaca tactctatca
    32521 aggaaagcac aactattgag agcttgattg atgagatgtt agctgctatg gataagaacc
    32581 tatctcctta ctatagtact atcaaatcta aaaacttgac tgtcaatgag ttgttgacca
    32641 ttgcttcctt ggtcgaaaaa gaaggtgcca agacagaaga tcgtaagctc attgcaggtg
    32701 tattctacaa tcgtttgaat cgtgatatgc cacttcaaag taatattgca atcttgtatg
    32761 cccaaggaaa actggggcaa aatatcagtc tagctgagga tgttgcgatt gataccaaca
    32821 ttgattcacc ttataatgtt tataaaaatg taggtctcat gcctggtcca gtcgatagtc
    32881 caagtctgga tgcgattgag tcaagcatca atcaaactaa gagcgataac ctctactttg
    32941 tagcagatgt cacagaaggc aaggtctact atgctaacaa tcaagaagac cacgaccgca
    33001 atgtcgctga acatgtcaac agcaaattaa actaaacaaa ctaaaattat gttatacttc
    33061 acataatttt ctttagaaaa tattatcaga agaaagttga gaaaaatggc agaaaaaaca
    33121 tatcctatga cccttgagga aaaggaaaaa cttgaaaaag aattagaaga attgaaattg
    33181 gttcgtcgac cagaagtggt agaacgcatt aagattgccc gttcatacgg tgacctttca
    33241 gaaaacagtg agtacgaagc agctaaggat gaacaagcct ttgtcgaagg acaaatctct
    33301 agcttagaaa caaaaatccg ctatgctgaa atcgtcaata gcgacgcagt tgcccaggac
    33361 gaagtagcga ttggtaaaac agtcaccatc caagaaattg gtgaggacga agaagaagtt
    33421 tatattatcg taggttcagc tggtgcggat gcctttgcag gtaaggtttc aaatgaaagc
    33481 ccaattgggc aggccttgat tggcaagaaa acaggtgata cagcaaccat tgaaacgcct
    33541 gttggtagct atgatgtaaa aatcttgaag gttgaaaaaa cagcctaaaa acagaaaaag
    33601 gagtggggag gcgatgtgct tcactcactc ctttttccat tttgctattc ttcgaaaatc
    33661 tcttcaaacc acgtcagcgt cgccttgccg tatgtatggt tactgacttc gtcagtttca
    33721 tctacaacct caaaaccatg ttttgagc
//
LOCUS       DBERCW010000023        33664 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.023, whole genome shotgun sequence.
ACCESSION   DBERCW010000023 DBERCW010000000
VERSION     DBERCW010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33664
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.023"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            467..1588
                     /gene="mnmA"
                     /locus_tag="ACL72M_001310"
     CDS             467..1588
                     /gene="mnmA"
                     /locus_tag="ACL72M_001310"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGS0716432.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1729..2184
                     /locus_tag="ACL72M_001311"
     CDS             1729..2184
                     /locus_tag="ACL72M_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0716433.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQYGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2194..4107
                     /gene="mnmG"
                     /locus_tag="ACL72M_001312"
     CDS             2194..4107
                     /gene="mnmG"
                     /locus_tag="ACL72M_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGS0716434.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4460..6139)
                     /locus_tag="ACL72M_001313"
     CDS             complement(4460..6139)
                     /locus_tag="ACL72M_001313"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS0716435.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6141..6374)
                     /locus_tag="ACL72M_001314"
     CDS             complement(6141..6374)
                     /locus_tag="ACL72M_001314"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGS0716436.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6654..6869
                     /locus_tag="ACL72M_001315"
     CDS             6654..6869
                     /locus_tag="ACL72M_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716437.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(7192..7344)
                     /gene="cibB"
                     /locus_tag="ACL72M_001316"
     CDS             complement(7192..7344)
                     /gene="cibB"
                     /locus_tag="ACL72M_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGS0716438.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7346..7531)
                     /gene="cibA"
                     /locus_tag="ACL72M_001317"
     CDS             complement(7346..7531)
                     /gene="cibA"
                     /locus_tag="ACL72M_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGS0716439.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7709..8392
                     /gene="tsaB"
                     /locus_tag="ACL72M_001318"
     CDS             7709..8392
                     /gene="tsaB"
                     /locus_tag="ACL72M_001318"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGS0716440.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8389..8826
                     /gene="rimI"
                     /locus_tag="ACL72M_001319"
     CDS             8389..8826
                     /gene="rimI"
                     /locus_tag="ACL72M_001319"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGS0716441.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENIFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8816..9826
                     /gene="tsaD"
                     /locus_tag="ACL72M_001320"
     CDS             8816..9826
                     /gene="tsaD"
                     /locus_tag="ACL72M_001320"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGS0716442.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9866..11172)
                     /locus_tag="ACL72M_001321"
                     /pseudo
     CDS             complement(9866..11172)
                     /locus_tag="ACL72M_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11508..12199)
                     /locus_tag="ACL72M_001322"
                     /pseudo
     CDS             complement(11508..12199)
                     /locus_tag="ACL72M_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12442..12996
                     /locus_tag="ACL72M_001323"
     CDS             12442..12996
                     /locus_tag="ACL72M_001323"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0716443.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKK"
     gene            13124..13648
                     /locus_tag="ACL72M_001324"
     CDS             13124..13648
                     /locus_tag="ACL72M_001324"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0716444.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLS
                     EIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVET
                     MRVYDELLEKSSHG"
     gene            13641..14594
                     /locus_tag="ACL72M_001325"
     CDS             13641..14594
                     /locus_tag="ACL72M_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0716445.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMSDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            14604..16220
                     /locus_tag="ACL72M_001326"
     CDS             14604..16220
                     /locus_tag="ACL72M_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0716446.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16569..16997
                     /locus_tag="ACL72M_001327"
     CDS             16569..16997
                     /locus_tag="ACL72M_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716447.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPSTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17009..17758
                     /locus_tag="ACL72M_001328"
     CDS             17009..17758
                     /locus_tag="ACL72M_001328"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGS0716448.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            17771..18943
                     /locus_tag="ACL72M_001329"
     CDS             17771..18943
                     /locus_tag="ACL72M_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGS0716449.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPFGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            19339..20202
                     /locus_tag="ACL72M_001330"
     CDS             19339..20202
                     /locus_tag="ACL72M_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS0716450.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            20488..20688
                     /locus_tag="ACL72M_001331"
     CDS             20488..20688
                     /locus_tag="ACL72M_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HGS0716451.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            20755..21420
                     /locus_tag="ACL72M_001332"
     CDS             20755..21420
                     /locus_tag="ACL72M_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0716452.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            21492..22718
                     /locus_tag="ACL72M_001333"
     CDS             21492..22718
                     /locus_tag="ACL72M_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0716453.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            23124..25025
                     /locus_tag="ACL72M_001334"
     CDS             23124..25025
                     /locus_tag="ACL72M_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0716454.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            25028..25891
                     /locus_tag="ACL72M_001335"
     CDS             25028..25891
                     /locus_tag="ACL72M_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS0716455.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            25971..27149
                     /locus_tag="ACL72M_001336"
     CDS             25971..27149
                     /locus_tag="ACL72M_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0716456.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            27242..29200
                     /gene="ligA"
                     /locus_tag="ACL72M_001337"
     CDS             27242..29200
                     /gene="ligA"
                     /locus_tag="ACL72M_001337"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGS0716457.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDIASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            29312..31591
                     /gene="pulA"
                     /locus_tag="ACL72M_001338"
     CDS             29312..31591
                     /gene="pulA"
                     /locus_tag="ACL72M_001338"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGS0716458.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            32136..33560
                     /locus_tag="ACL72M_001339"
     CDS             32136..33560
                     /locus_tag="ACL72M_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS0716459.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
BASE COUNT        10245 a         5810 c         7216 g        10393 t
ORIGIN      
        1 aggtgccctt gcagtcaaca caactgtaga cggatatact gtaaatgaaa acggtgaatg
       61 ggtttaagcc gattaaatta aatcatgtta agaacatttg acattttaat tttgaaacaa
      121 agataaggtt cgattgaata gatttatgtt cgtattcttt aggtacctgt cttatgattt
      181 caggaaatgt cattaaaaaa cgactccttt tctctaactt gaaaaataga ttagagaaaa
      241 tgggttgttt tatttattat agttatttga atgaagataa gaagaaggta tactcacgtc
      301 attcacataa tctgtatatt gactataagt tttaaaaaac aatttttaag ctcttccttg
      361 tcttctctaa ccaagcgtgt tataatgaat actgctcaag cgaccttcaa tcgtgaagca
      421 cacacgacct tcaatcgtga ataaacgaat agatgggaga cttaccatga gtgataactc
      481 taaaacacgt gttgtcgtgg ggatgagtgg tggtgttgat tcgtcggtga cggctctttt
      541 gctcaaggag cagggctacg atgtgatcgg tatcttcatg aagaactggg atgacacaga
      601 tgaaaacggc gtctgtacgg cgaccgaaga ttacaaggat gtggttgcgg tggcagacca
      661 gattggcatt ccctactact ctgtcaattt tgaaaaagag tactgggacc gcgtttttga
      721 gtatttccta gcggaatacc gtgcagggcg cacgccaaat ccggacgtta tgtgcaacaa
      781 ggaaatcaag ttcaaggcct ttttggacta tgccataacc ttgggggcag actatgtagc
      841 gactgggcat tatgctcgag tggcgcgtga tgaggacggc actgttcaca tgcttcgtgg
      901 cgtggacaat ggcaaggacc agacctattt cctcagccaa ctttcgcaag aacaacttca
      961 aaaaaccatg ttcccactag gacatttgga aaagcctgaa gttcgaaaac tagcagaaga
     1021 agcaggcctt tcgactgcta agaagaaaga ctcgacaggg atttgcttta tcggagaaaa
     1081 gaactttaaa aacttcctca gcaactacct gccagctcag cctggtcgca tgatgactgt
     1141 ggatggtcgc gatatgggcg agcatgcagg tcttatgtac tatacaatcg gtcagcgtgg
     1201 cggactcggt atcggtgggc aacacggcgg tgacaatgcc ccttggttcg ttgtcggaaa
     1261 agatctaagc aagaatattc tctatgtagg acaaggattc taccatgatt cgctcatgtc
     1321 aactagccta gaagccagtc aagtccactt tactcgtgaa atgccagaag agtttacgct
     1381 agaatgtacg gctaaattcc gttaccgtca gcctgactct aaggtgaccg tccatgtcaa
     1441 aggagacaag gcagaggtca tctttgcgga accacaacgc gcgattacac caggacaggc
     1501 agttgtcttt tacgatggcg aagagtgtct aggtggtggt ttgattgaca atgcttaccg
     1561 cgatggacaa gtttgtcagt acatttagat tgacaaattt tctcaatttg ctacaataat
     1621 aacagcaata gaaatgatgg tcaaagctca tggatgttgc aggctttttt gtcctgcact
     1681 tctttgtagt tttgactgtt tttgtgtcgt ttaagggaaa ggacaagaat gactcaacaa
     1741 gactttcgga caaaagtaga caatacggtt tttggtgttc gggcgacagc cttgattgtc
     1801 caaaatcaca agcttctagt taccaaagac aagggcaagt attacactat tggaggtgcg
     1861 attcaagtca atgaaagcac ggaagacgcg gtagtccgtg aagtgaagga agaactgggt
     1921 gttaaagctc aagctgggca gctagctttt gtggttgaaa atcgttttga acaatacggt
     1981 gtttcctatc acaatatcga gtttcattat ctggtggatt tgcttgaaga tgccccattg
     2041 accatgcagg aagatgagaa aaggcagccc tgtgagtgga ttgacttgga taagctccag
     2101 aatatccagc tagttccagc ctttttaaaa acagccctac cagattggga aggccaacta
     2161 agacacattc atcttgagga ataggagaga aacatgactt atcattttac tgaagaatac
     2221 gatattattg taattggtgc gggacacgct ggggttgagg cttccttggc cgctagccgt
     2281 atgggctgta aggtcctgct tgcgaccatc aatattgaaa tgctggcttt catgccttgt
     2341 aatccctcta tcggtggttc tgccaagggg attgtcgtgc gtgaagtcga tgccctcggt
     2401 ggcgagatgg ccaaaaccat tgacaagact tacatccaga tgaagatgct aaacacaggg
     2461 aaggggccag ctgtccgtgc ccttcgtgcg caggctgaca aggaacttta ctctaaggag
     2521 atgcgcaaga cggttgaaaa ccaagaaaat ctgacccttc gtcaaaccat gattgatgag
     2581 attttggtgg aagatggcaa ggttgtcggt gtgcgtacag ccacccatca agaatatgct
     2641 gctaaggctg ttattgtgac gacagggact gctctccgtg gggaaattat catcggagac
     2701 ctcaagtact catcaggtcc taaccacagc ttggcttcta ttaacctagc tgacaatctc
     2761 aaggaactgg gtctcgaaat cggtcgtttc aagacaggaa cccctccacg cgtcaaggcc
     2821 tcttctatca actacgacgt gacagaaatc caaccaggag atgaagcgcc taatcacttc
     2881 tcatacactt cacgtgatga ggattatgtc aaggaccaag tgccatgctg gttgacctat
     2941 accaatggta ccagtcatga gattattcaa aacaacctcc accgtgcgcc tatgtttaca
     3001 ggtgtggtca agggagtggg gcctcgttac tgtccgtcga ttgaagacaa gattgtgcgc
     3061 tttgcggaca aggaacgtca ccaactcttc cttgagccag aagggcgcaa tactgaggaa
     3121 gtctatgttc aaggactttc aaccagtctg cctgaggatg tccagcgtga cttggttcat
     3181 tccatcaaag gtttggaaaa tgcagagatg atgcggacag gttatgctat tgagtatgat
     3241 atggtcttgc ctcatcagtt gcgtgcgact ttggaaacca agaaaatctc aggtctcttc
     3301 actgctggtc agacaaatgg aacatcaggt tacgaagaag ctgctggcca agggattatc
     3361 gcgggtatca atgcggctct gaaaatccaa ggcaagcctg aattgatttt gaagcgcagt
     3421 gatggttata tcggggtgat gatcgacgac ttggtgacca agggaaccat tgaaccctac
     3481 cgtctcttga ccagtcgtgc tgaataccgt ctcattcttc gtcatgacaa tgctgatatg
     3541 cgcttgactg agatgggacg cgagattggc cttgtggacg atgaacgctg ggctcgtttt
     3601 gaaatcaaga aaaatcaatt tgataatgag atgaagcgcc tagacagtat caaacttaag
     3661 ccagtcaagg aaaccaatgc caaggttgag gagatgggct tcaaaccctt gaccgatgca
     3721 gtgacagcca aggaattcct tcgccgtcca gaagtttctt accaagatgt ggtggccttc
     3781 atcggaccag ctgcagaaga cttggatgac aagattatcg aattgattga aacagaaatc
     3841 aagtatgaag gctatatttc caaagccatg gaccaggttg ccaagatgaa acgcatggaa
     3901 gaaaaacgca ttccggccaa tatcgactgg gatgacattg attctatcgc aaccgaagcc
     3961 cgtcagaagt tcaaactcat caatccagaa accatcggcc aagccagccg tatttcggga
     4021 gtaaacccag cagatatttc tattttgatg gtgtatctgg aaggtaaaaa tcgtagtatt
     4081 tctaaaactc ttcaaaaatc aaaatgatac gtcgtcggct tcttacgaat gagttcaaag
     4141 cttggctttg attcatctcc agcctcccat agtttcccga actatgggag ctaactcaag
     4201 ttatgctttc gcttagcctt ctagtctgat ttcgattttt attgatactc ttcgaaaatc
     4261 tcttcaaacc gcgtcaacgt cgccttgccg taggtatggc tactgacttc gtcagttcta
     4321 tctacaacct caaagcagtg ctttgagcaa cctacggcta gcttcctagt ttgctctttg
     4381 attttcattg agtatgagtt ttaatctcaa aagaaagcat agagaaaaac agctccgagg
     4441 acggggctgt tttcttgctt tattcttcat ctggtgtgag gatcatcggg atgatgatcg
     4501 gttcacgttc ggtattttca tagaggaagg ggcgaatagc gttgacaatg gcaccattga
     4561 cagattgcac gctggcatcc ttatttttca gtgcgatacg aatggcattg aagaggatac
     4621 gctggctttg gcgaatcaag tcgccagact ctctcatgta gacaaagcct cggctgagga
     4681 tgtctggacc agacagaatc atctgcgatt tgaagtcaac agttgcgact gccagaacga
     4741 caccgtcttc agatagatcg cgacgatctt tgaggacagc tgcgccaatt tcaccgatac
     4801 gatttccatc gacatagata tcttgggcgt tgaaatgacc tgcgatacga gctgagtcag
     4861 cagtaagggc aagcacatcg ccattgctca tgataaagat attgtccttc tcaacaccag
     4921 tatccactgc tagtccagcg tggacttttt gcatgcggta ttcaccgtgg acaggcatga
     4981 agtattttgg cttaatcaag cagagcatga gtttttgctc ttgctgacca ccgtgtccag
     5041 atgtatggat attgttcact ttaccgtgga taacttcgac accagcttca gaaatgatgt
     5101 taatcagctt gttgacgcta gtagtgtttc cagggatggg actagaagag aagataacgg
     5161 tatcacctgg ttgtaattgt acttgacggt gggttccgtt ggcgatacga gagagagctg
     5221 ccataggctc accctgacta cctgtacaga ggataagaac ttctcctgca ggataatctt
     5281 tgatttcatt tggctcgata aaggttccct taggagcttt gatgtagcca agatcgattc
     5341 cgttgacaat ggccttttcc atagaacgac caaagaccgc aatcttgcgt ccagtcttaa
     5401 cagcagcttc tgttgcctgc tggagacgga agatatttga ggcaaaggat gcaaagatga
     5461 tacgtccttc aataccttgg ataatcttca taatggactg accaacgact ttttcagagt
     5521 tggtaaaggt tggtacttcc gcatttgtcg agtcagacag gagacagagc acgccttctt
     5581 caccaagcgc agccatacga tgcaagtccg caggttctcc aactggagta aagtcgaact
     5641 taaagtcacc cgtacagacg attttccctt gaggagtatg aatgacaatc cccaaaggct
     5701 ctggaataga gtgagtcgtt ctaaagaaag ttgccttgag atttttaaag gtcaactcgg
     5761 tgttgtggtt gatttcgtaa agtttggcgt tgcgcaagag gccgtgttct tcgagtttcc
     5821 cacggatcaa agccaaggca agcggtccag cgtagatagg gacatttgct tgcttgagta
     5881 ggaacggaat cccaccaatg tggtcctcgt gtccgtgtgt gattaaaaca gccttgacgc
     5941 ggtcgatatt gtccacgatg taagagtagt caggaatgac atagtcgata ccaagcaagt
     6001 catcttctgg gaatttaatc ccagcatcga cgatgataat ctcgtcttgg tattcaattc
     6061 cgtaagtgtt tttcccgatt tctcccagac caccgatggc aaaaacgccg acttcttcag
     6121 gtttaagagt ataggccata ttagaactcc gtgatttcga aggcgccagt ttctttttcg
     6181 taatcgagca atttgtcaga caagagttcg atatattcga tattgtactc tgggcgattt
     6241 tcttcgacaa gttggcgagc agtgatgcga ccctcaagtt ctgagctggc atcgatgtct
     6301 aggtaaagtg cgcgtgttgt ttcacggcgt gggctacgtt cttttgtttc ttgataaaaa
     6361 actttgtaaa tcatatagtt cctttctatt tacaggtcag cttattccaa acttttagca
     6421 gatatttgct tgatttcatt ccattttgtg tctagattga ccttgattcg ttacaattat
     6481 ttcaattata ccacaaaatg aaaaattagt aaaagacgga aacgagaaag ttaggggacg
     6541 atttctttgg taagcgtttg caagaataaa gaaaatgtat tatgttgata acggaagtga
     6601 aatttattgc ttgtcataat tccatataga ttttaagtca aggaggttgc cctatgtata
     6661 acttatttgc ttttgctatc ggagctcgct tggtagcttt tattgttttt gttgcttgcg
     6721 tttatgcggg gaatcttcta tttgccaaac tggaacgacg acaaaccaag ttcttgtgga
     6781 aaatgacctt tgtgactctc tactcgcttt ttctcctcct cgtgacctat gtcgtttggt
     6841 ttgtatttta ctttgaatta aatgcttaga tgccctgctt atgctggggt tttttgtttg
     6901 gggatgtaga gatagtagat ttacgacacg aaaattccac cccatctatc aagatgaggt
     6961 ggtctttgca tttttctaac atgacatgac aatggaattt tcaaagctta ttatttttat
     7021 gggagtcatt gttctgatca aaaatagagt tgaagcataa aaataaaaca atacaaacag
     7081 ataaatcgaa tggtaaaggg atggtagtaa tgttcaaatc attgagaatg ctgagcaaac
     7141 tgtaagagat gaagacaata aaatttatcc ttctaaaaat gtgtttctta tctagcatga
     7201 cttaccaaac tttttacgaa ggtcttttcc aatggtataa cctgccataa ataaagcgat
     7261 accaacaccg acaccaaagc cacccttgat ttcttgcaat tccttattag aaatttcacg
     7321 ataattgttc aaatctttca tcatattaat ctcctcctaa aaaataacca gctgccaaac
     7381 cagaacctat aagtgctgtt ccacctgcaa tagccttcca agatactgct actccaaaga
     7441 taaccaaggg agcgagaccg ccatcaatat ctgataattc attttcagat aaggataaaa
     7501 attgattgtc aagaatgtca aaatttgtca ttgaactttc ctcctttttt cttgttcact
     7561 tttatattcg gaaaagaaaa ggaaaagtga gcattttttt aaattatttt tagttaagtg
     7621 agggcactct tgtctggggg caaagaaaat tcccatgtgc cagcttttgt agtataatag
     7681 taagcagaca aaaagatagg aatgtgttat gaaagtatta gcttttgata cgtccagcaa
     7741 ggctctttct ctggctattt tagaggataa gcaggttctt gccgagacga cgattaatat
     7801 taagaaaaat cacagtatta ctcttatgcc tgccatcgat tttttgatgg caagtttgga
     7861 ttggacaccc aaggatttgg accgaatcgt ggtagctgaa gggccgggta gctatacagg
     7921 cttgcgaatt gcggtagcaa ctgctaagac cttagcttac accctgaaca tcgagttggt
     7981 tggtatgtcg agtctcttgg ctctggtgcc ccaccaacaa gaaggtttgt ttgtcccctt
     8041 gatggatgcg cgtcgcaata atgtttatgc aggattttat gaaaatgcca aacctgtcat
     8101 ggcagaagcg cacctatctt ttgaagaggt gctagaaaaa gtcaagggta ctagtcaggt
     8161 aacctttgtc ggagaagttg gcccctttgt tgagcagatt caaaaacact tgccaaggac
     8221 tgattacaaa gaaacattgc ccaatgcagc caatcttgct cttttagctt gggacaagga
     8281 agcagactcc ttgcatgatt ttgtgccgaa ttacctcaaa cgagtcgagg ctgaggaaaa
     8341 ctggctcaag aaccataccg agtctggtga gtcctacatt aaacgcctat gatagaaatc
     8401 aagcgaattc aacaacagcc tgacctagct caagccatct acgctgttat ggcagctgtt
     8461 tacctagtca gtccttggac tctggagcaa atccaagcag acctgtccca agaccagact
     8521 tggtatgttc tggcttatga tggggcagaa gtgattggtt ttctagctgt tcaggaaaat
     8581 atctttgagg cagaagtctt gcaaatcgct gttaaaggag cttatcaggg tcagggaatt
     8641 gcgtcagcct tgtttgctca attgccgaca gataaggaga ttttcctcga agtcagaaag
     8701 tcaaatcaac gagcgcaagc attttacaag aaagaaaaaa tggcggtcat cgctgagcga
     8761 aaggcctact accatgaccc agtcgaggac gccattatca tgaagagaga aatagatgaa
     8821 ggatagatat attttagcat ttgagacatc ctgtgatgag accagtgtcg ccgtcttgaa
     8881 aaacgacgat gagctcttgt ccaatgtcat tgctagtcaa attgagagtc acaaacgttt
     8941 tggtggcgta gtgcccgaag tagccagtcg tcaccatgtc gaggtcatta cagcctgtat
     9001 cgaggaggca ttggcagaag cagggattac cgaagaggac gtgacagctg ttgcggttac
     9061 ctacggacca ggcttggtcg gagccttgct agttggtttg tcagctgcca aggcctttgc
     9121 ttgggctcac ggacttccac tgattcctgt taatcacatg gctgggcacc tcatggcagc
     9181 tcagagtgtg gagcctttgg agtttccctt gctagccctc ttggttagcg gtgggcacac
     9241 agagttggtc tatgtttcgg aggcaggaga ttacaagatt gttggggaga cacgagacga
     9301 tgcagttggg gaggcttatg acaaggtcgg tcgtgtcatg ggcttgacct atcctgcagg
     9361 tcgtgagatt gacgagctgg ctcatcaggg gcaggatatt tatgatttcc cccgtgccat
     9421 gattaaggaa gataatctgg agttctcctt ctcaggtttg aaatctgcct ttatcaatct
     9481 tcatcacaat gccgagcaaa agggagaaag cctgtctaca gaagatttgt gtgcttcctt
     9541 ccaagcagca gttatggaca ttctcatggc aaaaaccaag aaggctttgg agaaatatcc
     9601 tgttaaaacc ctagttgtgg caggtggtgt ggcagccaat aaaggtctca gagaacgcct
     9661 agcagccgaa atcacagatg tcaaggttat catcccccct ctgcgactct gcggagacaa
     9721 tgcaggtatg attgcctatg ccagcgtcag cgagtggaac aaagaaaact tcgcaggctg
     9781 ggacctcaat gccaaaccaa gtcttgcctt tgataccatg gaataaagag tggctctttg
     9841 tcaagtgtag tgggtaggcg aaaagctaca atctggagag tacgaaattc gtactctctt
     9901 ttttgatgtt caaagtcatc aaaatccgtt ttttaaaatt gttaaagttc cggaaaccaa
     9961 aggctttgcg cttgataacc ttaatcaaat tattggtcgc ttcaagttta gcgttggaat
    10021 aaggcagctt aagtgcgttg ataatcttat ctctatccct taaaaaagtc caaaagaccg
    10081 tttgaaaaag cggatgaacc gttggcagtt cttgctcaat caatccaaag aaatggtcgg
    10141 cattcttctc ttgaaaatga aagagcagga gttgatagag ttcgtagtga acctgtaatc
    10201 cctcagagta agaaagcagc ttatctcgta cttcccgatg ggttaagtgc attcgaaacg
    10261 tgggctgata gaatcgtttc tgacagagct tgaagctatc ctggtgtagt aaatcagtcc
    10321 agtggactga tttagcccga gcctagaaac gaaaaagcga gggttccaaa agcgcttgag
    10381 cgcccgatac tccaaggatt ttcggtcaaa ttggttcatg atttggattc gtactcggtt
    10441 catagctcgg ctcagatgtt ggacaatgtg gaagcggtca agaacaatct tcgcctttgg
    10501 aaagagttgc ttagcgagcc gataataagg gctgtacatg tccatggtga tgacctcgac
    10561 cagctcccga acctctctct gatagcgttg gaaatggttt cgaatcaccg catgagttcg
    10621 cccgtctaaa attgcgagga tggatttgga ctcaaaatct tgggcaatga agctcatttt
    10681 gctctttttg aagctatact catcccaact cataactttt ggcaacttgg tccaatcggt
    10741 ttcaaactta aattccctca gttttcggat gacggtggaa gttgagaccg ccaatctgtg
    10801 ggcaatctca gtcatagact gcttttcaag gaggagctga gcgatttttt gtctcaccat
    10861 gttggaaatc tggcaatttt tcttgacaat ggatgtttga gaaacgacca ccttaaggca
    10921 attcttgcac tgaaagcggc gctttttgag atgtagtacc gtgggtaaac cctgacagtc
    10981 gagaagcgga attttagagg ctttctggaa gtcgtatttg atcatcttcc cttgacaatg
    11041 aggacaagga ggagcggggg aatccaactt tgcctgaacg actagatggg tttggtattt
    11101 cagaacagac aagattttga tatttttgtc tttcaatccg agcaaatctg tggtattctt
    11161 aagttgttcc atatgaaccc tttctaatga gttggttaga cgcttttcat tataggtcat
    11221 atggggcttt ttttctacaa gaaacgaccc tataattcct ggggtgggat tacccactac
    11281 agaaattata gagccaaaac attccaaagt cttgtctgac tctggaatgt tttctgttca
    11341 cagttgtttt gtaactgcct aataagtaac cgcgctataa cgaggtatct accgagattg
    11401 tcaattctcc agtatactgt tataaaaaac aaaactggag gattttttta tgtcccccca
    11461 tcgtcccatc gactgttccg tagctgccca ataacggagt atagtcggct gaaacaagaa
    11521 taggacaaaa gtgcctcaag aaaagcatcg taatttgaca atattattct gagatgtttt
    11581 tgatgtaagc ccatattttc tcaatgggat tatactcggg tgaataggta ggaagtggta
    11641 acagtctatg ccctgctcct tacacatgtt cattctgtga aaccttgcat tgtccataat
    11701 gataagggat ggtgtatcta aagtaggtag taagaatttt tggaagcaag cttcgaaaaa
    11761 gtcactcgtc atcgtatctt tataggtcat cggagccata gtatattgaa acaaaaaagg
    11821 gcattagtac ttctataaca gtatcgcaat ctctggtgtg cgttgtctcg atcttaattc
    11881 aaataattat atcttcttcc agagagacta actgcctgct caaggctcga tcatattcga
    11941 gataaaaata ggtctcaacc cctgtctcat aaatataaat aggagtcagg tagcttaagt
    12001 gattcaattc tttaaggaac cgatttactt tttctgggtc ttgttcgcag taggtacagc
    12061 tcttttttag actatatccc atagccttta gagcgtaatg aatagttgtt ggaggacagt
    12121 tgaattcagc agctatttca gtcaaataag catcgggatg agtttcaata tagatcttta
    12181 atttatctct atcaactttt tcaattaata gtggaagttt tcttaaagtt agtgtgttga
    12241 aacgttttta tacagtgcta aaatttgaag tgtagtgcag atgtatttgt aatagtatta
    12301 tagcaattct ttggagaagg tcgagacaag agaaaatagg tatctttgag atataagcat
    12361 gatttactat aaaattattg agttattcat aaaaatttct ctatcaaata tcataatgcg
    12421 tcgtttaagg agatggttac aatgcaatat agttgtggaa aaataaatat taatatccct
    12481 gatggatatg gagacattaa ggatatagtg ttttcggctc atattatagt taggtataat
    12541 aatggacatt gtggaggtat agatccgcat ataattggac tttgtaaaaa gcagatcaga
    12601 aggatgtctc tatatcctat tttgataatc gtatctagag attcaaaggt tattgatgat
    12661 tataaaaatt tagatattgc ctatgttgat tgtactcaat gttcaaataa ttttgaaact
    12721 gccttacacg ttaaaaatat tttaaaatta ttaaaaatcc aacttataca ctgtcatggc
    12781 tactcaacta attatttttt atatatgtta aaaaaacttg acaagaatgg atttggaaag
    12841 gttaagacag tgataacatg ccatggatgg gttgaatata acttaaaaaa gaaattcttg
    12901 acttattttg atttttggac atattctatg ggagatgctt ttatttgtgt atctgaaact
    12961 atgaaaaaaa gattggagag tataataaaa aaataagaag atagttgtaa taaataacgg
    13021 aattaatgta tcaaatagcg atttagatgt agtaggtgtt caagacttta aaaaagaatt
    13081 ttgtattcca aataacaaaa aaatcatttg ttatgttgga aggttggatc cagaaaaaag
    13141 gccggataga ttccttgaat ttgcagaaaa attattttta gtcagagaag atgtgatttt
    13201 tattatggct ggaaatggta gtatgtgggc tgctttgaaa gaaaaaattt gccatttgaa
    13261 atgtagagat aatttcaggt tacttggtga aatctatcca gctactatag tttaccaaat
    13321 atcggattta ttgtatattc cttctgatac agaaggaata cctatgtgtg ttttagagtc
    13381 aatgtcacaa ggaactccgg ttttagctag taatgttggc gggttaagtg aaattattga
    13441 acatagggtt gatggatttt tatttgagaa ggaagatgtt gagggagtgt gtgcttgtgc
    13501 taatttttta ctcaatgatt ctgagtattt gaaatatata ggtgagaata gtaaatcaaa
    13561 aataagaaaa catttttctg tgcaaaaaat gtttgtagaa accatgagag tatatgatga
    13621 attattagag aagagtagtc atggatagga atatagatca agaattagta agtattataa
    13681 taccaacaca taataggtat gaatctctga ttagagctgt gaaaagttgt ttacatcaaa
    13741 gttataaaaa tatcgaagtt ataattattg atgataatta tagtaatgta aatttaagaa
    13801 ataaaattat ccatcaattt ggctatacca atcatagaat taagttaatt ttaagtaatg
    13861 aagatttagg tgcaactaat gccagaaaca taggtatcaa aaattctaga ggtaagtata
    13921 tatcattttt agacgatgat gatgaatata tgtcagatcg aattttaaag ttgatggctt
    13981 gttttaaaaa gagtagaatg aagaatttag ctttagttta tagttatgga ataataattt
    14041 atccaaatgg tacacgagaa gaggagaaga ccgattttgt tggaaatccc ttgtttgttc
    14101 aaatggttca caatatagca ggtacgtcat tttggttgtg taaaaaagag gtgctagaat
    14161 taattaatgg ttttgagaaa atagattcac atcaggacgg tgttgtttta ttaaaactac
    14221 ttgctcaagg ataccaaatt gatatagtgc gagaattctt ggtgaattac tacgctcaca
    14281 gtaaagaaaa cggtatcact ggagtgacac aaaaaacaat taatgcagat gaagaatatt
    14341 ataattactg taggaaatat tttaatttat tgagtttcaa cgagagaata ttggttacaa
    14401 agaaatatta ttctttaaac ataaagcggt tactattaat aggagacaaa tgcaaggctt
    14461 taaaagtaat caagaaggca agagaagaaa aaatttttaa cgaatttctt tttttgaaat
    14521 atatgttatt atatcatttt ggttttttct attgtatata tgacaactat gttcaattaa
    14581 aatttagaaa gtgagaaact attgtgtata ctattataaa atcaaatata aaaaaattta
    14641 gtttattaac gatatttatt gttgctggtc aattattgct aatttatgca gcaactatta
    14701 atgctctggt gttgaatgaa ttaattgcga tgaatttaga gcggtttttg aaattgtcaa
    14761 tctaccaaat gattgtctgg tgtgggataa tattccttga ctgggtagtg aaaaattatc
    14821 aggttgaagt gatccaagag tttaatctag agattcgaaa tagagttgcc acagacatct
    14881 ctaactctac ctatcaagaa tttcatagta aatcatcagg aacatatctt tcgtggctaa
    14941 ataatgatgt tcagacttta aatgatcagg cttttaaaca acttttttta gtaataaaag
    15001 gaatttctgg tactatattt gcagttgtga ctcttaatca ctatcattgg tcattgactg
    15061 tagccacctt gttttcatta atgattatgc tacttgtacc aaaaatcttt gcatcgaaaa
    15121 tgcgagaagt tagtctaaat ttaactaacc aaaatgaagc ttttttaaaa tctagtgaga
    15181 ctatattgaa tggatttgat gtgttagcat ccttgaatct tttatatgta ttgcctaaga
    15241 aaattaaaga agcaggaatt ttattaaaga tggttataca aagaaagaca actgtagaaa
    15301 cgttagcagg cgctattagc ttctttctca atattttttt tcagatatct ctcgtttttt
    15361 taacaggcta tcttgcaata aaaggaatag tgaaaattgg tactattgaa gcaataggag
    15421 cactaacagg tgttattttt acagcgctag gtgaattagg aggtcaatta tcctctatta
    15481 ttggtacgaa gcctattttt ttaaaattgt attcaattaa tccaattgag tcaaataaaa
    15541 tgaatgatat cgaaccaaat gaggtgaata gagattttcc gttatatgaa gcaaaaaata
    15601 tttgctataa gtatggagat aaagaaatat taaaaaactt aaatttttgt tttcaacgta
    15661 atgaaaagta tttaatttta ggtgaaagtg gaagcgggaa atctacatta ttaaaattat
    15721 tgaatggctt tttgagagat tatagtggag aattgcgatt ctgcggggat gatataaaaa
    15781 aaacctccta tttaaatatg gtttcgaatg ttctatatgt agatcaaaaa gcttatttgt
    15841 ttgaaggtac gattagagat aatattttat tggaagaaaa ttatactgat gaagaaatac
    15901 tacagtcttt agagcaagtt ggtttgagtg taaaagattt tcctaataac attttagatt
    15961 attatgttgg tgatgatggg agattactgt caggagggca gaaacaaaaa attactttag
    16021 ctagagggct aattagaaat aagaaaatag tattaattga cgagggaact tctgctatcg
    16081 ataggagaac ttcgttagcg attgaacgta agatattaga tagagaggat ttgactgtca
    16141 ttattgttac ccatgctccg catccggaac ttaaacaata ttttactaag atatatcaat
    16201 ttccaaagga ttttatttaa gaatataggg gagggaaaca tgagattcta ttgtgaagct
    16261 tatgaggtaa ttactgaaga gaaaaaagta tactttaatg atattgagtt agaagttaag
    16321 tattcctctg tcgaagaatt gtttataata tgtgagaaat tattagataa gaaaaaagta
    16381 tcattttttt atgtagatga gaaaccctta aggtatctgt tatttgacta tatatttcta
    16441 ctagttctag ctaaaaaaat atcccaatct tatgaactgc accccaaaag ttagatttat
    16501 tctgtctaac ttttggggtg cagttcattt tgcatagttt tggcattcat cctagatatc
    16561 catataaaat gtctgagatt gttgaaatgt ctaaaaaaat atcagatcta aacgataaaa
    16621 aagaatttca caaaaagaac tgtgagttga ggtttcaaga tagtgttctt gataacataa
    16681 atagtgtccc gagtacaact catttattta gttgtttaaa tattcaaaca ttagtaaaaa
    16741 ttattttata tatttttcga tacaacagtt gtatgaaaat atttaatttt agagataaag
    16801 agcttatctt ttttaataag attgtaaatg ggctgataca aaatattgag gagaatttag
    16861 aggatgatat tgaaaggata ttgaaatatt tatatatatg tttatttaac gaaatattca
    16921 ttattaagaa taaggtgaat ttttttgatg atgtggaatt taatcagaca cttagtgagt
    16981 ttttagataa attgtagagg gaatggttat gagtaacaat actaagtata tctttttatc
    17041 tccacattta gatgacgcaa ttttttcctg tggtgattat atttcaaaat taacttcaga
    17101 aggagaaatt gtacttgtta ttactatatt ttctggttac cctttgagcc aacagctaca
    17161 gccctctgct aagcaatttc ataagttgtg taaccttggg aaatatccga ttgaagaaag
    17221 gaagaaagaa gacaggttag cttgtgaacg tctacagtgt gattttagac acttatcgta
    17281 ctatgaatgt ctctatagga aagatagaaa tggcaatttt ctataccgtc atatctatag
    17341 tgaattaaaa aatgaggaca cattaaagaa tgatatcata aaagagctgt taatgcattt
    17401 agacgacaaa tgtgtcgtat attgtccgct ttcacttggt gaccatgttg atcatgtttt
    17461 tgtgaatagt attggaaggg cgcttgaatt tatgcgttat aaagtaatat attatgagga
    17521 cttcccatat gtaagtgata gtagtatggt tagttatatg ggaaaaacta aagaattaaa
    17581 aatgtatcaa gaggaacttg atgaaaaaca ttatattgat agaatatcat caatattgtg
    17641 ctataaatct cagattttga taatctggaa atcagttgaa aaacttttaa acaatattaa
    17701 agagttgtat ttaaggaatg gggcagctta ttctattaga ttttggatta agaaataagg
    17761 aagtagtttt atgaatatag cagtaattgg tttggggcat gttgggctgg cctacgcgtt
    17821 actatttgca tctaaatata aagttgttgc atatgatata gattctgtaa aaataaataa
    17881 tttaaaaaag ggcattcttc catctaaaaa tgaagagctt atgaagtttt tttgcgagaa
    17941 taacttaaat attacttttt ttgatacatt ttctgaaatt aaaaataata ttgattatta
    18001 tattattgcg cttccgacag attatgatga gaaaattggt agttttaata catatgaaat
    18061 cgaacaaacg gtatcgaaga ttctgagggt aaaacctaat ggaaagatta ttttaaagtc
    18121 aacagttccg ttcggctttt caaacaaatt aaaaaggctg tttgatacaa aaaatatcat
    18181 ttttgtccct gaatttttga gagaaggttg ttctatatat gataatttat atccaagtcg
    18241 catagttgtt ggagatgaga cagttgaagg aagaaaaatt gcagagttgt tcctttcgat
    18301 tagtactcat agtactgcca atattaaaaa tgttatgtta gtttctccta ctgaagcaga
    18361 agcaattaag cttttttcta acacattctt agctctccgt gttgcttttt ttaatgaact
    18421 agattctttt gctgagagga gaagtttaaa tgctgaagtt gtaataaaag gtgtttgttt
    18481 agatccaaga attggaaatt tttataataa tctttctttt ggatttggag gatattgtct
    18541 tcccaaagat actaaacaat taaaaaaaga atttatagaa ataaatgccc cagtgataga
    18601 agcgattgat atttcaaaca caaatagaaa acagttcata gttaaacaaa tattggaacg
    18661 aaagccaaag atagtaggaa tatataaatt ggggatgaaa tataattcag ataattacaa
    18721 agagtcagct attttaagta taattaatga actattgatt gtcggtataa aaattttagt
    18781 atatgaacca aatttaaacg ttagtataga taacgtaatt tttgaaaaga attttgaact
    18841 atttacaaaa caaagtgatc taattgttgc aaatagatgg gataggggcc ttgaagctta
    18901 taaagataaa gtttacacaa gggggatctg gataagagat taactattga tattaaaaag
    18961 gcaataattt ataaaatttg tacaaaaaaa tgttaaattt tcacattttc atagtatact
    19021 gtttaataga aagtaggttc tttgtaaccg ctccattata aaatcctttc actcttccgg
    19081 tatactatta ggaaaaacat aactggagga tattttgagc tcacacctca tcgttccagt
    19141 ggctgttccc caagctcgtg tactgcccaa aaaagttaga cattctattt agaacgagga
    19201 ttgagttctg tattgtacaa ggctcggtcc ttttagagtc agcttaaggc tggctttttt
    19261 attttttcta actatcagaa tattttgaca aatgaacaca aataatgata taatatgcaa
    19321 aagctaggag gtggtaggat gattgaaaaa atggaattgg gggaatttta caaggaatta
    19381 cgtttggcga gaaagctcaa gcagtcagat gtggcttgtg acgggctaac agcttctcag
    19441 ttgtccaagt ttgagctagg gcagtccatg ttgtctgctg ataagctcat attagccatc
    19501 caagggatca atgtgacctt tgatgagttt gggcacaagc tcaacaacta tcaagaatct
    19561 ccacatatgc agattggtag aaaggttgtg gatcgctttg ctcatcaaga tatagctggc
    19621 ttagagcaac tgttggagga agtcgagcaa gaacagatgg cagagactta tcgtcgtttg
    19681 aatgctattg taatcaaaga tgccatccac tcactagata aaagctaccc actagcagag
    19741 gaggatagcg agtttttgac cacctatctc tatgctatcg agtcttggac ctggtttgaa
    19801 ctctatctct tttgcaatac tctgcccttc ttgagcaatc aagatctgat ctttttatca
    19861 acctccttac tcgaaaaatc caaagaattt aaagagttag tacacaatcg attgtatatg
    19921 aagcaaggac tcttaaatat catctcagag ctcatggagc gcaaactttt ttcttatatc
    19981 ccaatctttg aagccgagct ggagagtatg ctccgtccat acgatgtttt tgagaaagtg
    20041 ttgtggcagt ttttaaagaa gatgagcatt ttccttcaaa ctaagggaag caatcaaaaa
    20101 gagattgaac actttatcca atctctgcaa gtattagaaa atccacaatt aatagccctt
    20161 tttgaattgc gtttgcagca atacaaaaag cttatcgatt agttagaaat ggcaaaataa
    20221 taataatctc agcaacgatt ttcaataatg ttaaaatttg tttcttcata tttctccact
    20281 cctcattagt agtaacttta ttataccaga gaagtaatca aattcaccaa aatcgcaaat
    20341 ctgaaatttc tataagaaaa aatatcaaat atgcgatttt ctaaaataag ccaattttcg
    20401 tgttatactg tacttgtaaa gcacttgaag caaatcctag gtcgcagaag tggtttacaa
    20461 atgaagataa ttgaaggagt gtaaaagatg ttaaatttac aatttgcaga aacaatggaa
    20521 ttgacagaag ctgagttgga gatagtttat ggaggggaat ttgggaataa tgctgttatc
    20581 ccagccggtg cttggggagg gttcgggaca ccttggtcaa tcactaattt ctggaagaaa
    20641 aattttaacg atagacctga ctttgattct gaccgccgtc gttattaata tccaaagccc
    20701 ttgccttttc ttgggtaggg gctgtcttta tttcatagta taggaggaaa tagaatgaaa
    20761 aagataatct cacaccgcta ctttattata gtttttctac tagttattgc tgaccagaag
    20821 ttcagtgttc tagttttacg cagcgacctt gttactgggc tatctgactt tgcctattat
    20881 ctgtcggata tgatgttgaa ttttcttgtg gttttatttg ctcttattgc tatgatttgg
    20941 tcggggaaat ggcagaaaat caatagtaga aagtttaaag gatcctatct tttctattcc
    21001 ttcctagctc tgcttgcttt tgttgtttgg aatttcgtta ccttttttct tttcccacct
    21061 actcgaaatg aaatttctta tcaacatgct gctccgactt ttacaggggc tacagcattt
    21121 ttgatgtatt ttttctatcc tgtgattgca ggtcccattt ttgaagagat aatccatcgg
    21181 ggattggtga tgacagctct ggaaaaagga aagaaatggg ggctagatgt acttggctct
    21241 gctattttat ttggggtctc gcacattagt aatcacggtt gggtcttgac agactttgtc
    21301 ttctatatgg gtggaggtct tatatttgca gtcttattta gaatgacaaa gtcaatttat
    21361 tggcctattg gactgcatat agtctacaat ggtattggtc agcttttgat gttactgtaa
    21421 ttttggttgt tagtagtatc gcggtctatt cttggggaaa gattcccatt tgaacttaag
    21481 aaggagttgt aatgaaagta tttcttcaaa atagagattt taggcaatta actatcaacc
    21541 agtggatttc aacgcttggg gatacgattt tttatctggc cttcctgaat tatgtggcag
    21601 atgcgtcttt tgcccctttg gcgattttac ttatcacgat ttcagaaacc cttccccaag
    21661 ttctacaaat ctttctggga gttttggcgg attttcaaca tcatcgtgtc ttgaaataca
    21721 cagtcattag ttttacaaaa tttttgcttt actctatagt gtccctatcg ctttcagggc
    21781 agtctttttc cttgttgcta gtaaccttta tttgtatgat taacctcttg tctgacacat
    21841 tgagttattt ttcaggcgcc atgctcactc cgattttcat tagaattatt gggcaagatc
    21901 atctggcaga agctattgga tttaaacagt caactgttag tttagtgaaa acaatcagta
    21961 atatcctagg aggagtctta ctaggtattc tatccatcca gtttatttcc ttactgaacg
    22021 ctcttacctt tttaatcgca tttttaggta tcctcttcat aaaaactgac ctcttgaaag
    22081 tagaaaaaac gattagctat caagaaggac tctctgtaaa atccttttgc cagcatttgc
    22141 tccaatcatc gaaattgata tggaatatga ataaggtgct cttggttttg tttattatct
    22201 ctactagtca agcagtgata aatgttacag ttcctgtctc tactctattt ttgaggaatc
    22261 aacccttttt gaatttacaa acaggtcaat ctcttgcctt gctatccact tttgaactgt
    22321 cagccctgat tgtcggaagc cttgtaagtg gctatctgca acataccatt tccataaaaa
    22381 cagctctcta tgcctcactt gtcatccagt tgcttcttct agtaggattt gccacagttc
    22441 gttttgactg gattctcatc tttagtacct tggatgcctt tttcgcaggt gttctctctc
    22501 ctagattgca agaactcgtc tttaaacaaa tacctgagga gtcaatggga gcagttcaat
    22561 cttctatcag tgccattacg gttgttttac ctagcttatt tacaatatct ttggtaacca
    22621 ttgctactag ctttggaact ctggcagtta gctttgtttt attgctattt cttctagttg
    22681 cctttgttat gcttctgaat attcgtgaaa gtatttagtg gagaatttct ataatatatg
    22741 tttgagactg gattgccagt ctttttatga tggtcaaaat caacagactt tttctctttt
    22801 ctgaatgtgt tatagtagac tgaatctaaa atagtacgaa acaattgcta aaacatttat
    22861 agaaattaat tttactttcc caatcgattt gttctcatct tatttcaatc tgctatacgc
    22921 gtacgtaaat aatgaaaaga attaaataat aggcttgtgc gataactatt tgaaacaaga
    22981 ttagctggtt agaaaatcca acaagatagt gaaggaatct aatataaaat atacataatt
    23041 tagtttattt tatgttataa aagttgtact aaaagactta cgattatctt gaatgcctta
    23101 gggaaacatg ctatactact tgtatgatta ttttacaagc taataaaatt gaacgttctt
    23161 ttgcaggaga ggttcttttc gataatatca acctgcaggt tgatgaacga gatcggattg
    23221 cccttgttgg gaaaaatggt gcaggtaagt ctactctttt gaagatttta gttggagaag
    23281 aggagccaac tagtggagaa atcaataaga aaaaagatat ttctctgtct tacctagctc
    23341 aagatagccg ttttgagtct gaaaatacca tctatgatga gatgcttcat gtctttgatg
    23401 acttacgtcg gacagataaa caactgcgtc agatggagct ggagatgggt gaaaagtctg
    23461 gtgaggattt ggataaactg atgtcagatt atgaccgctt atctgaaaat tttcgccaag
    23521 caggtggctt tacctatgaa gctgatattc gagcgatttt gaatggattc aagtttgacg
    23581 agtctatgtg gcagatgaaa attgctgagc tttctggtgg tcaaaatact cgtttggctc
    23641 tagctaaaat gctccttgaa aagcccaatc tcttggtctt ggacgagcca actaaccact
    23701 tggatattga aaccatctcc tggctagaga attacttggt aaactatagc ggtgccctca
    23761 ttatcgtcag ccacgaccgt tatttcttgg acaaggttgc gacaattacg ctagatttga
    23821 ccaagtattc cttggatcgc tatgtgggga attactctcg ttttgttgag ttgaaggagc
    23881 aaaagctagc tactgaggca aaaaactatg aaaagcaaca gaaggaaatc gctgctctgg
    23941 aagactttgt caatcgcaat ctagttcgtg cttcaacgac caaacgtgct caatctcgcc
    24001 gtaaacaact agaaaaaatg gagcgtttgg acaagcctga agctggcaag aaagcagcca
    24061 acatgacctt ccagtctgaa aaaacgtcgg gcaatgttgt tttgactgtt gaaaatactg
    24121 ctattggtta tgacggggaa gttttgtcac aacctatcaa cctagatctt cgtaagatga
    24181 atgctgtcgc tatcgttggt ccaaatggta tcggcaagtc aacctttatc aagtctattg
    24241 tggaccagat tccttttatc aaaggtgaaa agcgctttgg cgctaatgtt gaggttggtt
    24301 actatgacca aacccaaagc aagctgacac caagtaatac ggtgctggat gaactctgga
    24361 atgatttcaa actgacacca gaagttgaaa tccgcaaccg tcttggggcc ttccttttct
    24421 caggagatga tgttaaaaaa tcagtcggca tgctatctgg tggcgaaaaa gctcgtttgc
    24481 ttttagctaa attgtctatg gaaaacaata actttttgat tctggatgag ccgaccaacc
    24541 acttggatat tgatagtaag gaagtgctag aaaatgcctt gattgacttt gatggtacct
    24601 tgctttttgt cagtcatgat cgttacttta tcaatcgtgt ggcaactcat gttttggaat
    24661 tgtctgagaa tggttcaact ctctaccttg gagattacga ctactatgtt gagaagaaag
    24721 caacagcaga aatgagtcag actgaggaag cttcaactag caatcaagca aaggaagcaa
    24781 gtccagtcaa tgactatcag gcccagaaag aaagtcaaaa agaagttcgc aaactcatgc
    24841 gacaaatcga aagtctagaa gctgaaattg aagagctaga aagtcaaagc caagccattt
    24901 ctgaacaaat gttggaaaca aacgatgccg acaaactcat ggaattacag gctgagctgg
    24961 acaaaatcag ccatcgtcag gaagaagcta tgcttgagtg ggaagaatta tcagatcagg
    25021 tgtaaagatg gaacatcttg gaaaagtatt tcgtgaattt cgaacaagtg gaaattattc
    25081 tttaaaggaa gcagcaggcg aatcctgctc tacctctcag ttatctcgct ttgagcttgg
    25141 ggagtctgac ctggcagtct cccgtttctt tgagattttg gataacattc atgtaacaat
    25201 cgaaaatttc atggataagg caaggaattt tcataatcat gaacatgtgt ctatgatggc
    25261 acagattatc ccactttact attcaaacga tattgcaggt tttcaaaagc ttcaaagaga
    25321 acaacttgaa aagtctaaga gttcgacgac ttccctttat tttgagctga actggatttt
    25381 gctacaaggt ctgatttgtc aaagagatgc gacttatgat atgaagcagg atgatttgga
    25441 taaggtagca gattatctct tcaaaacaga agaatggacc atgtatgagt tgattctttt
    25501 cggtaacctc tatagtttct acgatgtaga ctatgtcact cggattggta gagaagttat
    25561 ggagagggag gaattttacc aagagattag tcgccataag agattagttt tgattttggc
    25621 cctcaattgt taccagcatt gtttagagca ttcttctttt tataatgcca actattttga
    25681 ggcttataca gagaagatta ttgacaaagg tattaagctt tatgagcgta atgttttcca
    25741 ttatttaaaa ggttttgcct tatatcaaaa aggacagtgt aaagaaggct gtaagcagat
    25801 gcaaaaggcc atgcatattt ttgatgtgtt aggtcttcca gagcaagtag cctattatca
    25861 ggaacactac gaaaaatttg tcaaaagtta attttcccaa ataagggaaa aaataaaaag
    25921 ctcctttcgg ttttgataca atagtttcaa aatttgagag gagctttaat atgaatcgct
    25981 atgcagtgca gttgattagc cgtggggcta tcaataaaat gggaaatatg ctctatgatt
    26041 atggaaatag tgtctggttg gcttctatgg ggactatagg acagacagtt ttaggaatgt
    26101 atcagatttc tgagctcgtc acatctattc tcgtcaatcc ctttggcgga gttatttcag
    26161 accgtttttc tcgtcgtaag attttaatga cggcagatct tgtttgtggg attctttgtc
    26221 tggctatttc tttcataagg aatgatagct ggatgattgg cgctttgatt gttgctaaca
    26281 ttgtgcaggc tattgctttt gccttttctc gcacagccaa taaagctatc ataactgaag
    26341 tggtggagaa agatgagatt gtgatctata attctcgctt agagctggtt ttgcaggttg
    26401 taggtgttag ctctcctgtt ctttccttcc ttgttttaca gtttgcaagt ctcaatatga
    26461 cgctactgct agactcgctg acttttttca ttgcttttgt tctagtggct ttccttccaa
    26521 aagaggaagc aaaagttcaa gagaaaaagg cttttactgg gagagatatt tttgtagata
    26581 tcaaggatgg gttacactat atctggcatc agcaagaaat tttcttcctt ttgctggtag
    26641 cttccagcgt taatttcttt tttgcagctt ttgaatttct acttcccttt tcgaatcagc
    26701 tttacgggtc agaaggagcc tatgcaagta ttttaactat gggggctatt ggttccatca
    26761 ttggggctct tctagctagt aaaattaaag ctaatattta taatcttttg attttactgg
    26821 ctttgacagg tgtcggagtt tttatgatgg gattaccact tccaactttt ctttcctttt
    26881 ctggaaattt agtttgtgaa ttgtttatga cgatttttaa tattcacttt tttactcaag
    26941 tacaaaccaa ggttgagagc gaatttcttg gaagagtact gagtacaatt tttaccttag
    27001 ctattctatt tatgcctatt gcaaaaggat ttatgacagt cttgccaagt gtacatctct
    27061 cttctttcct gataattgga agtggtgtta tcatcttgtc ttgtatatcg tttatttatg
    27121 ttcgaactca ttttgaaaaa ttgatataag gttgcttgag tttcaaaaat aatttcaaac
    27181 taagtgtttt ttccgccctt ctcgtttgtg aggagggctt gttttatggt aaaatggtct
    27241 tatgaataaa agaatgaatg agttagtcgc tttgctcaat cgctatgcga ctgagtacta
    27301 taccagcgat aatccctcgg ttgcagacag tgagtatgac cgcctttacc gtgagttggt
    27361 cgagttagaa actgcttatc cagagcaagt gctagcagac agtccgactc atcgtgttgg
    27421 tggcaaggtt ttagatggtt ttgaaaaata cagtcatcag tatcctcttt atagtttgca
    27481 ggatgctttt tcacgtgagg agctagatgc ttttgatgcg cgtgttcgta aggaagtggc
    27541 tcatccgacc tatatttgtg agctgaaaat cgatggctta tctatctcgc tgacttatga
    27601 aaaggggatt ttggttgctg gggtaacacg tggagatggt tcaattggtg aaaatatcac
    27661 agaaaacctc aagcgtgtta aggacatccc tttgactttg ccagaagaac tagatatcac
    27721 agttcgtggg gaatgttaca tgccacgcgc ttcctttgac caagttaacc aagtgcgcca
    27781 agaaaatgga gagcctgaat ttgctaatcc tcgtaatgcg gcagcaggaa ctctgcgtca
    27841 gttggataca gcagtagttg ccaagcgtaa tcttgcaacg tttctctatc aagaagccag
    27901 cccttcaact cgtgatagcc aagaaaaggg tttgaagtac ctagaacaac taggttttgt
    27961 ggtcaatcct aagcgaatct tggctgaaaa catagatgaa atctggaatt ttatccaaga
    28021 agtaggacag gaacgggaaa atctgcctta cgatattgat ggagtggtaa tcaaggtcaa
    28081 cgacatagca agtcaagaag aacttggttt tacagttaag gctccaaagt gggcagtagc
    28141 ctacaagttc cctgccgaag aaaaagaagc tcaactctta tcagttgact ggacagttgg
    28201 ccgtaccggt gttgtaactc caactgctaa tctaacacca gtacaacttg ccggtacgac
    28261 tgttagccgt gcgaccctgc acaatgtaga ttatattgct gaaaaagata tccgaaaaga
    28321 cgatacggtc attgtatata aggctggtga catcatccct gccgttttac gtgtggtaga
    28381 gtccaaacgg gtttctgaag aaaaactaga tatccctaca aactgtccaa gttgtaactc
    28441 tgacttgttg cactttgaag atgaagtggc cctacgttgt atcaatccgc gttgccctgc
    28501 tcaaatcatg gaaggcttga ttcactttgc ttctcgtgat gctatgaata ttacaggcct
    28561 tggtccatct attgttgaga agctttttgc tgctaattta gtcaaggatg tggcggatat
    28621 ttatcgtttg caagaagagg atttcctcct tttagagggg gttaaggaaa agtccgctgc
    28681 taaactgtat caggctatcc aagcatcaaa ggaaaattct gccgagaagc tcttatttgg
    28741 tttgggaatt cgtcatgtcg gaagcaaggt tagtcagctt ttacttcaat atttccattc
    28801 aattgaaaat ctgtctcagg cagattcaga ggaagtggct agtattgaaa gtctaggtgg
    28861 cgtgattgcc aaaagtcttc agacttattt tgcgacagaa ggctctgaaa ttctgctcag
    28921 agaattgaaa gaaactgggg tcaatctgga ctataaagga cagacggtag tagcggatgc
    28981 ggccttgtca ggtttgaccg tggtattgac aggaaaattg gaacgactca agcgctcaga
    29041 agctaaaagt aaactcgaaa gtctgggtgc caaagtgaca ggtagtattt ctaaaaagac
    29101 cgacctcgtc gtggtaggtg cagacgctgg aagtaaactg caaaaagcac aagaacttgg
    29161 tatccaggtc agagatgagg catggctaga aagtttgtaa tggatcgttt aaaaacagag
    29221 tttagagaat atgactatgt ctgttaattg agacgagatt gacaaaaatt tattagtgaa
    29281 atagaaacaa agtaaaaagg aaaaataaaa aatgtataac taccctatgc gcattcatta
    29341 ccatcgtaag aatggagaat atgacacttg ctcctttgta aaaagtcagg atcaacgaat
    29401 tgatttgcta acctacaaag aagattattt tggagcttta tttagctttg aacacccaag
    29461 ttcacatgtt atagaaagct tgaattttgt ggttcataca ggtcaaacta gtaaagaata
    29521 ttctatccgt tttaatcact atcccctatt aacagaggtc tggattttgg aaggcgatga
    29581 taggatttat tactctgaaa atcctgctat tgccagtcct ttctataaaa atcaaaatcc
    29641 ttttgccttt gataaggcca ttaacagtgc tagttttgac catcattggg gttaccaagg
    29701 agaattgggt tgccgtgtag aggacaatca ggctcatttt tccctctggt cacctacagc
    29761 gacagaagtg caagttgtcg tttatgaatc agctgctaat gatgcacccg tttggaagac
    29821 ttttgagatg aaaagaggca atagctactc ttataatcat aaggacaata caatcggtgt
    29881 ctggagtttg gatgttgagg aagatttggt aggtaaggct tatcagtatc aagtccaatt
    29941 ccctcatcac caaacactga cacgtgatcc ttatacaatc gcgaccagcc ctgatggcaa
    30001 acgttcagct attctgagcc atgtagaaaa gcaagttgaa aacttcgagg ttaagcacgg
    30061 ttcggaggct acttggcgct tggaaaatcc atgtaaggca gttatctgtg aaatgcatat
    30121 tcgtgatttg actaaatcac ctacatcggg tgtagatgaa catcttcgag gaactttctt
    30181 gggtgctgct caggctggaa cagttaacca atacggccag tcaactgctt ttgattacat
    30241 caagaagctg ggctacaatt atgttcaatt gcaaccaatt gcagaccgtc ataaagaata
    30301 cgatgaggat ggaaatgtaa cctacaactg gggttatgat ccacaaaact ataacgcgcc
    30361 agaaactagt ttttcaacta atccagatga tccagctcag gtcattcgtg atttgaaggt
    30421 gatggttcaa gcttatcacg atgcgggtat tggagtcatt atggatgtag tctataacca
    30481 taccttctca gttgttgatg caccattcca aacaacagtc cctgattact attatcgtat
    30541 gaatccagat ggtaccttcc agaatggaac gggtgttgga aatgaaacag ccagtgaaca
    30601 cgaaatgttt cgcaagtata tgattgattc tcttctatac tgggtgcagg aatataatat
    30661 tgacggcttc cgttttgact tgatggggat tcatgatgtc aagaccatgc agatgattcg
    30721 tcaaagcttg gatgaaatcg actccaacat tatcctctat ggagaaggat gggatatggg
    30781 aacaggtctt gccccttatg ataaggccaa gaaggacaat gcctaccaga tgccaaatat
    30841 tggtttcttt aatgacaatc agcgcgatgc tgtcaaaggg ggagaagttt atggtgctat
    30901 caagtcaggt tttgtcagtg gtgctgcgac agagccaatt ctagctaaag caatcctagg
    30961 aagtcgtgaa ttaggaagct atacacatcc aaatcaggtg cttaactatg tagaagccca
    31021 tgacaattac aatcttcacg atttattggc aacccttcat ccagaccaaa gttcagagca
    31081 aatcatgcgc aaggtcgaaa ctgccacagc catgaatctg ctcatgcagg ggatggcctt
    31141 tatggaaatc ggtcaagaat ttggtcgtac caaactggtt gcgactggtg aaaatggtga
    31201 gttgacccat gatgatagag agcgtgcgat gaatagctat aatgctcctg acagtgtgaa
    31261 ccaagtgaac tggaacttga ttaatgagcg tcaagacagt attgagttta tccgtcaagt
    31321 catccgattg aagacaaaaa ctggtgcctt ttcttactct agctatgatg aaatttacca
    31381 tcatgtcttt gtgcattctg cgattgaaca tagcggctac cttatctatg aagttcacgg
    31441 caaagaacac ctcttggtgg ttgtgaatgc taaatcagaa ccctatcaat ttgaaaatgc
    31501 aggaaattta gctatgttgg taaccaacag tcgctcaaaa gaagataatg ttttaaatga
    31561 tattagtcta gctgtcttga gtgttttata aataccatct atctcgctat ttttacacag
    31621 acaaattccc agttatgagt attagtaaaa aatccattca ttgaaattga aagaatagaa
    31681 agaacctggc taacagctca cttgtataga aaatttgata aatattttca caaaacaaga
    31741 cctcctatca aagtttttga acacttgata ggaggtcttt ttattatgaa gacttttacc
    31801 tagactttgt ttcagcaatc tatgacagtt atagtaggct gaaattggag tagcacaccc
    31861 ttgtttctga aacattgtga gaaattggtt tggctgtccc caaccaaatt gttcagtttt
    31921 tttattttac tatagatgat actcattcac gctcttcgaa aatttcttca aaccacatta
    31981 gcctcgcctt gacgtagtgg atttttttta tttttattga gtatactttg aaaaatcaag
    32041 tttgtgaaaa taatctcaaa aattttgcaa aaagggttgt gattttctga aaatttggta
    32101 aaatatatct taatcatttt caggaggaca agaatttgac aagatatcag aatttagtaa
    32161 atggaaaatg gaaatcatct gaacaagaaa ttacgattta ttcaccaatc aatcaagaag
    32221 aattgggtac agttccagcc atgactcaga ctgaagctga tgaggctatg caagctgcgc
    32281 gtgcagccct gccagcatgg cgagctttat cagcagttga acgtgcggct tatttacata
    32341 aaacagcagc tattttagaa cgcgataagg aagaaattgg tactatcctt gccaaagaag
    32401 tagcaaaagg gattaaagca gcaattggag aagtagtgcg tacagcagac ttgattcgtt
    32461 atgctgctga ggaaggtctc cgtatcactg gacaagcaat ggaaggtggt ggttttgagg
    32521 cagcaagtaa aaacaaactg gctgttgtcc gtcgtgaacc agttggtatc gtgctagcga
    32581 ttgctccctt taattatcca gttaatttat ctgcttctaa aattgcacct gccttgattg
    32641 cagggaatgt ggtcatgttt aagccaccaa cacaaggttc catttctgga ctcttgttgg
    32701 ctaaagcatt tgaagaagca gggattccgg caggtgtttt caacaccatt acaggtcgtg
    32761 gttcagaaat tggggattat atcattgagc acaaagaagt caacttcatc aactttacag
    32821 gttcaactcc tattggagaa cgtattggtc gtttagctgg tatgcgtcct atcatgttgg
    32881 aacttggtgg gaaagatgca gctcttgtac tagaagatgc agatttggaa catgctgcca
    32941 agcaaattgt tgcgggagcc tttagctact caggacaacg ttgcacggcc attaaacgtg
    33001 tcattgttct cgaaagtgta gcagataaat tagctacttt gcttcaggaa gaagtttcta
    33061 aattaacagt tggtgatcca tttgacaatg ctgatattac acctgttatt gacaatgctt
    33121 cagccgactt catttggggc ttgattgagg atgcacaaga aaaagaagct caggctctta
    33181 caccaatcaa acgtgagggc aatcttctct ggccagtgct ttttgaccaa gttacaaaag
    33241 atatgaaagt ggcatgggaa gagccatttg gtcctgtttt accaatcatt cgtgtggcta
    33301 gtgtagagga agctattgcc tttgccaacg aatctgaatt cggccttcaa tcatcagtct
    33361 ttacaaatga tttcaaaaaa gcctttgaaa ttgctgaaaa acttgaagta ggtacagtcc
    33421 acattaataa taaaacccag cgtggtccag ataatttccc attccttggt gtcaaaggtt
    33481 ctggagctgg agtgcaagga attaaatata gcattgaagc gatgacaaat gtcaaatcca
    33541 ttgtttttga tgtgaaataa cgtgtaaaac caggaaattg ttttcctggt tttatttttt
    33601 tgctataaaa taataataat tatagaaaaa atacgaactt tttggtatta taatagattg
    33661 aaac
//
LOCUS       DBERCW010000024        33636 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.024, whole genome shotgun sequence.
ACCESSION   DBERCW010000024 DBERCW010000000
VERSION     DBERCW010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.024"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(372..521)
                     /locus_tag="ACL72M_001340"
     CDS             complement(372..521)
                     /locus_tag="ACL72M_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGS0716460.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            486..605
                     /locus_tag="ACL72M_001341"
     CDS             486..605
                     /locus_tag="ACL72M_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGS0716461.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL72M_001342"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL72M_001342"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGS0716462.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL72M_001343"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL72M_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGS0716463.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYENQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="ACL72M_001344"
     CDS             complement(2517..3044)
                     /locus_tag="ACL72M_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS0716464.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL72M_001345"
     CDS             complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL72M_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGS0716465.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     VALTEK"
     gene            complement(4466..9376)
                     /locus_tag="ACL72M_001346"
     CDS             complement(4466..9376)
                     /locus_tag="ACL72M_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGS0716466.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYRFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            9669..11299
                     /locus_tag="ACL72M_001347"
                     /pseudo
     CDS             9669..11299
                     /locus_tag="ACL72M_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            complement(11858..13465)
                     /locus_tag="ACL72M_001348"
     CDS             complement(11858..13465)
                     /locus_tag="ACL72M_001348"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGS0716467.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDTEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13855..14442)
                     /gene="rpoE"
                     /locus_tag="ACL72M_001349"
     CDS             complement(13855..14442)
                     /gene="rpoE"
                     /locus_tag="ACL72M_001349"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGS0716468.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14570..15019)
                     /locus_tag="ACL72M_001350"
     CDS             complement(14570..15019)
                     /locus_tag="ACL72M_001350"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716469.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15024..15413)
                     /locus_tag="ACL72M_001351"
     CDS             complement(15024..15413)
                     /locus_tag="ACL72M_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGS0716470.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15441..16091)
                     /locus_tag="ACL72M_001352"
     CDS             complement(15441..16091)
                     /locus_tag="ACL72M_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS0716471.1"
                     /translation="MRDKQTFLMKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16081..16644)
                     /locus_tag="ACL72M_001353"
     CDS             complement(16081..16644)
                     /locus_tag="ACL72M_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0716472.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16809..17043)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17097..17600)
                     /locus_tag="ACL72M_001354"
     CDS             complement(17097..17600)
                     /locus_tag="ACL72M_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGS0716473.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17793..18623)
                     /locus_tag="ACL72M_001355"
     CDS             complement(17793..18623)
                     /locus_tag="ACL72M_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0716474.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18608..20290)
                     /locus_tag="ACL72M_001356"
     CDS             complement(18608..20290)
                     /locus_tag="ACL72M_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716475.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20392..20649)
                     /locus_tag="ACL72M_001357"
     CDS             complement(20392..20649)
                     /locus_tag="ACL72M_001357"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716476.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(20656..21204)
                     /locus_tag="ACL72M_001358"
     CDS             complement(20656..21204)
                     /locus_tag="ACL72M_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGS0716477.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21219..22067)
                     /locus_tag="ACL72M_001359"
     CDS             complement(21219..22067)
                     /locus_tag="ACL72M_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGS0716478.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22255..23604
                     /gene="trkA"
                     /locus_tag="ACL72M_001360"
     CDS             22255..23604
                     /gene="trkA"
                     /locus_tag="ACL72M_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGS0716479.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23608..25047
                     /locus_tag="ACL72M_001361"
     CDS             23608..25047
                     /locus_tag="ACL72M_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS0716480.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25172..25573)
                     /locus_tag="ACL72M_001362"
                     /pseudo
     CDS             complement(25172..25573)
                     /locus_tag="ACL72M_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
     gene            26971..27255
                     /locus_tag="ACL72M_001363"
     CDS             26971..27255
                     /locus_tag="ACL72M_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716481.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            27582..27800
                     /locus_tag="ACL72M_001364"
     CDS             27582..27800
                     /locus_tag="ACL72M_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716482.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(28167..30491)
                     /gene="pflB"
                     /locus_tag="ACL72M_001365"
     CDS             complement(28167..30491)
                     /gene="pflB"
                     /locus_tag="ACL72M_001365"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGS0716483.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            30885..31946
                     /gene="dinB"
                     /locus_tag="ACL72M_001366"
     CDS             30885..31946
                     /gene="dinB"
                     /locus_tag="ACL72M_001366"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGS0716484.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(32093..32938)
                     /locus_tag="ACL72M_001367"
     CDS             complement(32093..32938)
                     /locus_tag="ACL72M_001367"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGS0716485.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(32969..33106)
                     /locus_tag="ACL72M_001368"
     CDS             complement(32969..33106)
                     /locus_tag="ACL72M_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716486.1"
                     /translation="MRYQTHYQLKQKLWLDPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            33193..33636
                     /locus_tag="ACL72M_001369"
                     /pseudo
     CDS             33193..33636
                     /locus_tag="ACL72M_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT         9999 a         7233 c         6191 g        10213 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 aacctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttggcaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattag tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttgaaattg aatttttcca tagtgactcc ttaattttct
      541 tctacacgtc tgatgataaa tctaattcgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acgaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaagct agtatagatg tgatctccga gagcagcttt aaccacttca tcttctgtca
      841 aagctttcaa agcgttgtga agagttgatg gaaggtctgt aataccagct tccttgcgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccata caaaccaact tccaaaagaa cagccatagc aacgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatggcagt atagttgtaa gcatgcttga
     1201 tcaaaccgcc taggaaatgg taagctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgcat caaacaagga catattacag tgcatacctg
     1321 agccagcaat accaaatttt ggcttcgcca taaatgttgc gtaaagtccg tgtttgcgag
     1381 caatggtttt aacaacaagt ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 cgtacttaaa gtcaatctca tgctgtccaa ccgcaacctc gtggtgactc gcttctactt
     1501 caaatcccat tttggtcaag acattcacaa tctcacgacg tgtgttgtcc gcaaggtcag
     1561 taggtgccaa atcaaagtag ccacccttgt cattcacttc aagtgttggg tccccatttt
     1621 catccaactt aaataggaag aattctggct ctggaccaag gttgaaggat ttgaatccaa
     1681 cttcttccat gtgacgaaga gctcgtttca aattaccacg agggtcaccc gcaaatggtt
     1741 caccttctgt tgtataaaca tcacagatca gacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtccg ggtacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acataacctt gttcgacaag accttatcta
     1921 actgttcatc tgtagcagga atttcgacgt ttttcatggt tcccaaaata tctgagaaca
     1981 taagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcataag ttttctcctt aatctatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaaa cgcccctgtt ggaggagttc attgtgaagt gcacgacgta
     2161 cttcagtctg actaaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 tttcataata acgaatctga cgcgccgata gatcggtcaa cttcataaca ctgccgatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattaataat gttataaaat gtaacattat
     2521 ttttcttttt tctctaaaaa gagacgaata cgatcaatat cgtaatttac gataattgcg
     2581 acaaaaactc ccataaatgt ttctaataca cgcacaaaca cgtacaaaat tgtctcacca
     2641 cttggaattg atagggtaat aattaacata gctgctacac caccaataac ccctgctttg
     2701 ttattcatgg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga agaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctc atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaag
     2941 ccaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttgaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactttcatc cctctcttct ttgatttgtt tataaaatct
     3181 tatttttctg tcaaggctac aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccga ttgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atgtcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccgatt
     3661 tcgatacctt gtgctttgta gaatgtgtaa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg agataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgcttccaat
     4081 tcagcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtca
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattaca ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga cttttttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattcgaaa ctattatatc acactttaga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctaaact agcaagacca aggctggcta agcctgctat tagggcttca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccgtttt
     4741 catcaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcgttgtt
     4801 ccccaactag catctcagca ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagccgg ttgataagta ggttttggaa
     4921 ggactgtgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtga ggtgctgtaa agataacatg actatccgtt tgttcaaaag
     5041 ccaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcat aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaac ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tggcttgtct tctttcaata
     5341 aagcaaccag atcttttaga ctctgtttcg ctgttgcaag ctcttctgga ctcaaatcta
     5401 ctttttcaac caaggccttg tttttctcaa gaagcggagc tagggcagaa cctgaaggat
     5461 ggtttggttt ggcagccaag agttcttgaa cctcacctgt taaacgatca agctctgtct
     5521 tttcttcctt aaatttctct tgaccattca gagctttatg agcttctgtc aatttattaa
     5581 gtcggtcatt gacttgatct tgggtgctag tttcatggtc tttcaacact tgttcggccg
     5641 cttcaattgc tttcaagaaa gcttctttta cttctggtga agcaaagtta tagaccacct
     5701 tgttcttagc agcttcaact tctgctaatt tttgtttgag gtactcatcg ttcaatgctg
     5761 cttttggaga taccaaaaca tcaaagttga cttcatgacc ttggtaacga agcgtcaagg
     5821 tttgacgacc agtcttttga gcatcgtaac cagaaatttc aactccctca tcagtaaagg
     5881 aatgttcttc catggtgtca ttgctataag ccactgcaaa gcgtccttca gacaagtcta
     5941 agctatcacc aactaggtaa tcttttttcg gttcctgact tacttcaatt cccaaaatag
     6001 ttttcggact tgcttcgtct tggccagtga cagtcactga caaattagca tttactggtt
     6061 gtcccaaata ttggagagta agattctgtt ctcccttatg atgcgtatca aaacctgata
     6121 ctgatacacc tgcgtgagtt aggcgaatga gttcgtcctc agttcctcct tcatactgaa
     6181 ctcgaagaac accacctcta aggtccaaat cctccccttc ggcgtagctt gttttcttag
     6241 gtcctgtttc taggctgact gacttgattc ttctgtcatc ttttggaacg gaaactgcta
     6301 ggacattact aatttccttg cctggcaact gggtacgata ataaagaaga ccagattgat
     6361 ttgtcaaatc caatggtgca cttgctaggt ctcctccaac ttcgctcttc aaggttgcga
     6421 gtggagtttg agaatttgga ttatcataaa cggtaatagt tgctccagcc ggtacatctg
     6481 caaagccaac ttgtaccttg ttattgccta gagaacgggc tgcagccttg gccatcggaa
     6541 tattgacact ctcagtatca agcttttcat acattttcca gttatagata cgaatagcct
     6601 tccatggagt tccattgtca gaagtgacaa cattcaagcg ccagtcttga gcagtgattg
     6661 gtttatcaag agtgatatct gtcacgtgtg ctttgttgcc acggacttcc ttagctagct
     6721 tccactcacc atctgcatct ttataataaa ggtcaaagtc tttggtgttc atcaagccat
     6781 cgttaacaga ctcaccacca gcccctgcat gatccatgac ccatctaaca acggtacgtg
     6841 gcttggtcaa acgaatatcc acactaccac tcaactgagc tgaagaccat ttatctgaca
     6901 agctagtaat ggtaccgttc aacatacctt caataccttc tccaccttct gtatctggga
     6961 aggtacttcc gataacagta gcccctggaa cgatgttttc tgctagaggt cttggaagac
     7021 ttgtgtcttg gacagtcatc ccccactcaa aggttgtggt tgcagcttct gaacgaactc
     7081 catttttacc gactgctaca accttcagtt cttgagttgt accctgagca cttgctgagc
     7141 ggctaacttt tggtagataa atagttgtag aagatgagcc agttagtaat ttccagctgt
     7201 ctccatcttt ttcataaact tcatagaaat ctgcatcctt gttgccttta aattgcacaa
     7261 ctgcttccgc ttcttgggca tttttaagag attgtttcac tacagaaaag cttgtcggcg
     7321 attgtggctc ttggtgattg tccgagatag ttaattgtcc taggttgaac cgataatctt
     7381 ttacagcacc ttcatgctcg aaaaatagtt tgactgcata gatggtttta cctgctagtg
     7441 agctgagatc aaattcttca tttgtccagt tgtcagaaag ggttagctct ttccatgcat
     7501 ctgcatcatc gaatttgtag tctggagttg tagagaatgc catataaact ttagaacctt
     7561 ttcctccctt gtgggcaaca cgaagtttgg tcttctcagt tacttctaac ttagtagaat
     7621 aaagtctcac atcctgatct gtcttaccgg ctacatcacc agagaattta agggaatttc
     7681 cgccattata ggcatctgta aaatcatatt ctgcacgaag tttttcccct gttgaagtct
     7741 gccaccagcg ccatgttgga agaacacctg atactgaacg ataattccac tcagaatcct
     7801 tagaaacctt accatctacg aaccattttt taccatgacc tgtattaaaa gaagtagtaa
     7861 aagtattacc taccgctggc gtacggtccg caactaggtt agcaatacca taccaatctt
     7921 tgtcacctgg tttttgacca gtagggtctc cttgataacc tgtaaagaag atatcttcat
     7981 ttttatgata atcttcacca gtttttccta aacttgtaat ggtatctggg gcaaataaac
     8041 caagagaaag gcgcaatttc ccattttcgt ctaaaatgtc attccactta acctttgtct
     8101 tgtaggaacc accctgttgc aattccaaac ctgcaaatac atcataagga ttacgaccaa
     8161 tccagttggc agttgcaata gtgtaatcat ttttagcctt atcccagtta aagttagcaa
     8221 agaagttatc tgccggaacc ttatctcctt ctggttgcat gaattggtag ttgtattctc
     8281 ccaaaccatc ttgatggtaa cgtccatagt tataggtcat ggcatcatac caagaatact
     8341 tgattggatg gtttacctta gcagcatatt ccttgctata gagcataaac tggcgcatct
     8401 tttctccaag aggtttaacc aaatctccag ttgtttcttg gttgatgaaa tagccatcat
     8461 agccataata cttggccatg tctaccaatt tacgggcaat tgggaagcta ccatctgcgt
     8521 cttgcttcaa agcttcagca aatctttctt gatctgcaat actattagac cagttgaaga
     8581 agagtgtacc gtatacagga accccgttac ggtgacctgc atcaataacg tcaggagttg
     8641 gtacgagacc ttcccagaag accattgaat ctagatattg ccaatagtca aaagcatagg
     8701 ccttgaactc ttctccacca acagaagcat ggtcttttgc tttagaattg gtgtttgata
     8761 aggcttgaac ttttgcttcc ttgctagctt tttcattgac taaatgacct gtccgacgtg
     8821 aagcgaggac aacagatccg cggttaatag catcatcttc acgagcacct ggttcccatt
     8881 ttaacaattc ttcccaagaa ttaaatttga tttcctttgg ttttaatgtt ttttctgtat
     8941 ttttagggac atctggctgg acttcttttt cagtcttatt agcttctgct gctggcttag
     9001 actcatcccc ttggttagtt gcttcgggct ttgcttctgt ttccttgtca gacttaggtt
     9061 ttgcttctgc agatggtgtt tctgcaacca cctcacctgc tttttcctct ggtttagctg
     9121 cgctagctgc ttctgccttt tctagcttgt tttctctagc atgttcccct tcattctgct
     9181 tatcagcttc attggtcgaa tgctcactct ctcctgaaac aagctctgta ttagctccgc
     9241 tattttcagg aactgcagtt tcttcagcca aggctggacc agcaaataaa acagcaccaa
     9301 tcatcagcga gcaggctcct actgataact tacgaatact gtaacgacaa cgtctttcaa
     9361 aaaatggatt cttcattttc tcctcctaaa agattgattt tgttgtttta aagaaagcgc
     9421 tttatattct gtagtttttt atcaaactct agaaccatga taatcacatt tttatcctaa
     9481 aacattttta gacaaaaaac aataactgtt tgcacaaatc taaaataagg ttaaaaactc
     9541 ttaaaaataa tacacttatc aattataatt ttcttttaca aacttgacat taacacttgt
     9601 tagatttact tttatccttt aaaatagaat aggagatatt ccgcgattat ttttcggagg
     9661 aaaaagaaat gtccattaat tggcaggaaa ttttatttca ctttttaggt ggtctggggc
     9721 tattcttata tagcatcaag accatgggag acggtttgca acaagctgct ggagatcgcc
     9781 ttcgttttta cattgacaaa tatactagta atcctttctt tggagttctg gttggtattg
     9841 ggatgactgc tctaattcag tctagttctg gtgtaacagt tattacagtc ggcctggtca
     9901 gtgccggtct cttaacctta cgtcaggcta tcgggattgt catgggtgct aatattggga
     9961 caactgtcac atcctttctc atcggtttta aattaggtaa ctatgcccta cctatgctct
    10021 ttatcggtgc cgtctgtctc ttttttacga aaaatcggac agtcaataat atcggacgca
    10081 tcctctttgg tgtcggtggt atcttttttg ccctcaatct catgagcggc gcaatggctc
    10141 cactcaagga tttacaggtc tttaaggact atatgattga gctaagtaag aatcctgttt
    10201 tgggtgtctt tgtcggtacc ggcttgacct tgctaattca agcttcttcg gctaccattg
    10261 ggattttaca aaacctctac gccggcaatc taattgacct acagggagct ttgccagttc
    10321 tatttggtga caatatcggg acaaccatta cagccatcat tgcctcttta ggggctaata
    10381 ttgcagctaa acgggtagca ggagctcatg ttgccttcaa cgttatcgga acagtcgtct
    10441 gcgttatttt tctagttcct tttactgtcc tgattcattg gtttgaagct acgctaaatc
    10501 tagcaccgga aatgaccatc gcctttgctc acggaacctt aatattacca acaccattgt
    10561 ccaatttcca tttatcggag ctctggctta ctttgtaacc aagattattc ctggagagga
    10621 cgaggttgtc aaatacgaac ccttatatct tgatgaacat ttcatcaaac aagccccatc
    10681 tatcgctcta ggaaatgcta aaaaagagct cttgcactta ggaaactacg ctgctaaagc
    10741 ctttgacctt tcctataagt acatcattga cttggatgaa aaagttgctg aaaaagggca
    10801 taaaaccgaa gaagcaatta acaccatcga tgagcaatta acacgttatc tcattgccct
    10861 ttcaagcgaa gctctcagcc aaaaagaaag tgaagtgctc accaatatcc ttgattcctc
    10921 ccgtgatttg gaacggattg gagaccacac ggaggctcta ctcaatctga ctgactatct
    10981 tcaacggaaa aatgttgaat tttctgatgc cgccttgaaa gaattagagg aagtttaccg
    11041 ccaaactagt gactttatca aagatgctct ggatagtgtg gaaaacaatg atattgaaaa
    11101 agcacgcagt cttgtagaac gtcatgaagc aatcaataag atagaacgtg ttctcagaaa
    11161 aacccacatc aaacgcctca acaaaggcga atgttcaaca caagctgggg tcaactttat
    11221 cgacatcatc tcacactaca ctcgtgtatc agaccacgct atgaaccttg ctgaaaaggt
    11281 ttttgcagaa caaatctaat aaccaagaag ctatccatca taattggatg gcttcttact
    11341 ttttcctaag caagactagg ctgaatgaaa ctgaaagagt attctgcaga tatatagtat
    11401 attgaaacta gaatagtaca cctctatttc taaaacattg ttagaaatcg atttgactgt
    11461 cctgatcgat ttgtcctgtt attatttcat tttactatag tggattaaat taaaaaagta
    11521 taatgtattg aatctataac agtacatctt gactgctaaa atatttctat aaattaattt
    11581 gactttcctt atagagatgt tcacatctta tttcaattca tgatacaatc cagttcctaa
    11641 aactttgcta gaaattaatt tggctttccg aattaatttg ttcagatttt atttcatttc
    11701 aatatactga taaatccatt cactagcaca gggcaagagg gagtcgctat tgatttcaac
    11761 ggtagcaggt acatacagag gactcctacc tcagatatac tgcaatatca tcgtatgcaa
    11821 aaaacctctg agatttttct caaaggttct gattttgcta attgctgttc tcaaccgctg
    11881 cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg acggcttgac agttcagggt
    11941 gatactgaca agctacaaag aatttatttt caggaatttc cacgatttct accaaacgat
    12001 tgtctggaga aactcctgaa aagacaaaac ctgctgcctc aaactgctca cggaaggcat
    12061 tattaaactc ataacggtga cggtgacggc gttgcaccac ttcttgattg tgataagcag
    12121 cagcagcctt agagccacgt ttcaacttag acggataaag tcccaaacga agggttccac
    12181 ccatatcctc aatatcaatc tgatcacgca tgatatcaat gatagggtat tttgtttctg
    12241 gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac gtgacgagca aactcgatac
    12301 atgtcaactg cattcccaag cagactccca acattggaac atcattttca cgcgcatagc
    12361 ggatggcttg gattttccct tctgtaccac gttgaccaaa accacctggt acgatgatcc
    12421 cgtccgcatc agacaagagt tctgctacat tctctgctgt cacatcattg gcattgaccc
    12481 aattgatttt aacttctgta tcattgacat agccagagtg tttcaaggct tcgaccactg
    12541 agatataggc atcttgcaac tccacatact taccaacaag ggaaatctta acttgtttct
    12601 tgaggttcat gaccttgtcc accatggctg accattctgt catagccgct gctggtgcgt
    12661 ctaatttcaa atgatcacaa acaatttggt ccatcccttg tgcctgcaag ttcagtggaa
    12721 tttggtaaag gtgttcaaca tccaacgatt cgataacggc ttctggtgcc acatcacaga
    12781 actgggccag tttattttta attccttgac cagctggctc ttctgtacga ataaccaaca
    12841 tatttggttg gattcccaag ccacgcaatt ctttgacaga gtgttgggtt ggtttggttt
    12901 tcatttcacc agcagccttg aggtaaggaa gcaaggttgt atggatatac atgacattat
    12961 ccgcacccac atctgccttc atctgacgaa gagcctctag gaatggcaag gactcgatat
    13021 ctcctactgt tccaccaacc tctgtgataa tgacatcaga gtcggtcgtt agagcggcac
    13081 gcttgatttt ttctttcaaa gcatctgtga tatgaggaat gacttgaaca gttgccccaa
    13141 ggtattctcc acggcgttct ttacgaagaa cttcactgta aattttccca gttgtcacgt
    13201 tggaatattt gttgagattg atatcgataa aacgttcata gtgacccaag tccaaatctg
    13261 tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg gtaaggactc atggttcccg
    13321 gatcaatatt gatataaggg tcaaactttt gaatggttac tttgagacca cgatttttca
    13381 agagacggcc tagactcgct gccacaatcc ctttcccaat agacgatacc acaccaccag
    13441 ttacaaaaat atatttcgta gacatagatt cctctttcta aaatgctcaa ggtcttgtta
    13501 actacgaggg gatatagaaa acaagaccct actaataaga ataatctggg acgactgcac
    13561 cagattcaca actaatactc ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg
    13621 tagatatgtg ttcctgactt tgtcagtctt atctacaacc tcaaaacagt gttttgagca
    13681 gcctacggct agtttcctag cttgctcttt gattttcatt gagtataaaa tacaagaaga
    13741 taacttcttg aaaaaacaaa aatagctccc taagaactag ggagccccga cctctaaaag
    13801 aggtgcccaa acaatatgat acctaaaaat aggataattg tcaatagcta actcttattc
    13861 ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg tcttcgttga gatccacatc
    13921 ttctcccaag tcatctggag cgatttcgtt gatttctgca tcataagctt ccacttcatt
    13981 tttttcatca tctggatttt catcatcgta tgaaagagct ggatctgctt cgtatgcatc
    14041 ttcgtcttct ggatcatctg cattgtagtc aatggcatct gaatcaccat ccataaaggc
    14101 attgacacgt tttttcttag cttttggtgc tacttcatcg tcgtcatttt cttcaagagc
    14161 gatgatttct tcgtcgattt cgtccacacc ataccatgaa cgaagacccc atttgttgtc
    14221 cccaagtgag atgaagctac cgtcaaagtt caactctgtg tagaacagag gcaaagcttc
    14281 gcggatatcg ctgtttgatg ttccaaggta gttttgaatt tcgtttacaa gatcgctaaa
    14341 atgcatctca tgatcgcgac cacgaagttc taatatagca cgcgctacct caatcataga
    14401 tagttcactt ttttcttgcc cagcaaatac ttctaattcc aaagcgtttc tcctcattta
    14461 tactactatc gccagagcga acagactctg acctcatttt atcatttact ctttatttta
    14521 cgataatttt gcggaatagt caaaggttaa gggggagaaa gtggcaggat tagactaatt
    14581 ccaatataaa actccttcct ttttctgttg ctccattttc cacaaatcca agcgacttga
    14641 aacacctcct agaagcatga ttgtaggtgt agatttcctt gactctcaat tctttccatc
    14701 cttttactcg agccaattca atcaaagcac ttagaatctt ttttccaagt cctcgatgtt
    14761 ggtaagcgga attcccaatc acaatgggga gattatcctg agatagtgta atatccccaa
    14821 ttggaaacca ttctcccttc tccttgactt caatccaaaa aagctcacca tgccgatcca
    14881 aataggaata catggcttcc aaggtcgctt gactgtaagg aagcttcacc ccatctacga
    14941 ggtaaaccaa gttcacatcc tgataccaag caaaagcttc ctcacaatga ttgaccttat
    15001 aataaggaac aaaacacaat gcactacctt ttcaacaaaa gagttgctgc ttgattaaaa
    15061 ccatcacacc agttatacca ttttgcttca tacccatctt gagctaggat acgatcttct
    15121 aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt gcgcatagag atgatatagt
    15181 tcatcaccac catctctatc ccactcagca gaaatcgtat cccgatctgc caataaagtc
    15241 tgataagccc tgtgatgccc atctgtaatc agcaaacaat ctccaaaggc aagaatactg
    15301 attggatcga cttggattgt ttctgccgac tggtaaagca tctgaatatc ttgcaacttc
    15361 ttttctgata aatatagttg agtcggatga agatctgcta tgttgacttt catttctttc
    15421 tcctcaaggg aattcgatac tcacttctgt ttgcctttaa atcgccattg gaagcggagc
    15481 ttgtcataga agggaaactc gataaacagg actcccaagc ccacacagag actggcaagg
    15541 acgtctgatg ggtaatgaac tcccagatag actcttgata ccagcacact gactaggtag
    15601 aggccaagga cgatttgtac gatttttctc cagactggat ctttaatccg ctgactaaga
    15661 ataacaatca aagtacctac catcaaggtt acagccagag aatgcccact tgggaaggaa
    15721 aatcccttct cctccaccag atgtaagata tctggccgtg ggcgctggta gatattttta
    15781 aaggtcacga ttaaaagacc tgccaaagcc agatttccca gcatgaagaa actttctatc
    15841 ttccatcgct tacgataaaa gacaaaagct gtaatgacaa cccaagtgat aatcactggg
    15901 atatcaatca gacgtgtgag ggctcgaaaa agaatagtca aataatctgg taagtctcct
    15961 cgaatggcag tctgaatcga ttggtcaaaa ttgaccagcg tttcagggta aaatttgacc
    16021 atgtagccaa gaataacgaa aagtaaaagg gcaaaactgc ccttcattaa aaatgtttgt
    16081 ttatctctca taatgtttta aggttggttt caagagaaca tacaacaacc agaatgaaac
    16141 ggaaaagata acaccttcaa tcaagttaaa aggtaatacc atggtcatta ggtagttgga
    16201 aagtcccaaa atttttccaa tatcaaagtt agcaaactta gcgtacaaag gaacagcata
    16261 aacatagttg agaaccaaca tggccaaggt taaaccaata gttccagcta gagagcctag
    16321 taggaaacga agggttgtcc gttccttttt ccaaatcaaa gcaaatacga tgacaaaaac
    16381 tcccaaagct acgatattca tcggcaaacc aatgtaagta ttcactcctt ggctgttaag
    16441 aagcaacttc aagagtgagc gaagcaagag cactcctaga gcagcaggca aatccatgac
    16501 caccagaccc acaaggactg gcaagatact aaattcgatc ttgaggaaag atgccgctgg
    16561 taaaagcgga aaatcaaagt acatcagcac aaatgagatg gctgatagaa ttgcaatggt
    16621 cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat tttctataaa atcagaagaa
    16681 gttggaaagg attcctctat ctattctcac tttttatatc ccaaaagttc cctcttactc
    16741 tattaaagaa aaacaaagca agtggttaca atccggctat aaatctatca aaacagacaa
    16801 agctattctt tcgtcttctc ccatccagac tatactgtcg gttgtggaat ctcaccacat
    16861 cagcttgcgc tcgcggactt ctttaaaggg aaagaaatag agatttttct tttagactag
    16921 gcgacaagct gtaggcataa cttctggtta ggcaaagctt gtcaacaaag tataaaagga
    16981 aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat cacaccctgc cctgaagact
    17041 cttttatcat aacaaaaaac gcttgcaagc gcaagcattt tgttcatttt cattttttat
    17101 ttcaatttat ccacttcata ggtatggacg agctcaagac ctgcaaagtt ctgctggcga
    17161 agagcctcat agacaatcat gcagacggta ttagacacat tgagactgcg gacatgttca
    17221 tcattcatgg gaatacggag agccttctca ggatgttctc gcataaaatc ttcaggtaag
    17281 cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt cagtcgataa atccacctca
    17341 gaatagattt tttccgcgaa tttcgaaatc agatagagtt ttcccttcat ctgagatatg
    17401 aaatcttcta aactctcgta aaaataaatc tctagcttat cccagtaatc caatccagcc
    17461 cgcttcatct tgcggtcatc aataggaaag cccataggct tgatgatgtg gaggggagaa
    17521 ttggtcgcag cgcaagtacg cgcgatattg cctgtatttt gtggaatttg aggttcaaat
    17581 aatacaatgt gatttgtcat gacttgcttc ctttcaccat tgcaaaaaaa tagccacact
    17641 gcccggagtc aagctcagca aacagcgtgg ttaaggcatc gttaacttac ctcacaacag
    17701 gtttgaagta aatcagcgaa actactttct tagtataaca ctttcagaat cattgtcaat
    17761 agaaatgact tgattttttc aattttttca agctatttcc aagggttgta aaatcgtccc
    17821 tgattctgca agataagtag taaactaact actaaaaaca aggttgccaa gagcaaggta
    17881 atatagtctc cttttttcaa ggcctgataa ctataccatg tgcgtttttt ctctttccca
    17941 aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc gttctagcga gctaaaaatc
    18001 aagggcgtaa taatgagcag attgcctttg attcgttgca taagagaagc tttcttggat
    18061 aattccatcc cacgcgcctc ctgagacatc ttgatagtaa agaattcttc ctgcaaatct
    18121 ggaatatagc gcaaggtcag gctgacagaa taagcaatct tatagggcac accaatttga
    18181 tttaaactgg aagcaaactg actaggatgg gttgtcatca aaaagataat agccagagga
    18241 atggtgcaaa gatacttaat ggccaaattt agcagataaa agagctcctg gctggttaga
    18301 gtgtagacac cgattccctg ccaaatcaca cttctctctc cataaagtcc aaccccatac
    18361 tcgggagaaa agagatagac catcaaaacg tttaaaacgg caaataccgt cgcaaaaacg
    18421 gctacaaagg aaacatcttt aaagcgaatt tctgataaat agaggagaaa gactgaaaag
    18481 atggcaatca gcaagagcat tctggtatca tagctaatca tggccgccaa tgataccaga
    18541 atgaaaaaga gaagtttccc agctcctgac aagcgatgaa tcacagtatc tctatgctgg
    18601 taaccgatta atttagcttg catccctctc tcctttcttt gtaaaatgcc gttaaatcca
    18661 gtggatccac atctagtttc ttagccaagt taaagatgga ggtttctttt agattggctt
    18721 ttactaacag ctcaggatcg ctcaacagac tggctggaac agtatcggca atcaattctc
    18781 catccaccat gacaaggacc cggtctgaat aatccagcat caattgcata tcatgggtaa
    18841 tcatgacaat ggtatgccct ttttgatgta actcttcgag aaattccata atctcagtat
    18901 agttcttctg atcttgacct gcagtcggtt catctaggag aataatttca gctcctaaga
    18961 ccaaaattga agcaatggtg acacgttttt tctgaccaaa tgacagggca gaaataggcc
    19021 aattacggaa ttcataaagt ccacagattt tcaaggtttc atagactctc gtttcaattt
    19081 ccttctcatc cacacctcgc aaacggagcc ctagagccac ctcatcaaaa atcatattgg
    19141 ttgaaatcat ttgattagga ttttgtagca catagcctac tcgttccgcc cgctctgcaa
    19201 cagaatcgcc ttttatatcc tgtttttccc aaagatagcg tccttccgtc tgaataaagc
    19261 tacttatagc cttggctaga gttgatttcc ctgctccatt ttttccgaca atagcaatct
    19321 tttcaccctt tttaatatct aaatgtaggg attttaaaat cggtctatca tcataagaga
    19381 aagacacgtc ctctaattta aagagtgact gcaattctgg agtttctttt gccagttcat
    19441 tctgcagctg aacctgacct tttgagatag acatgttatc cagattcgct aactgttctt
    19501 ccttgactaa gtccacacct aattgacgga gagtcgttag ataaaggggt tctcgaattc
    19561 cattttgagt caataaatca gtcgcaagca actggtcagg gctcccatta aaaaggatac
    19621 gaccatcgct tatcaagaca atccgatcca cagggcgatg cagaacatcc tccaaacggt
    19681 gctcgataat cagagtcgtc gtcccctctt ccttatgaat ctggtcaatc aattcgataa
    19741 tatcctgacc tgacttggga tctagattgg cgagtggctc atcaaacaag agaatcggac
    19801 tttcatcaat caagacacca gccagactga ctcgctgctt ttgtccacct gacaaatcct
    19861 gaggacgctg atccagtaaa ggaagaaggt ccagcttttc agcccattta taaacacgac
    19921 ctttcatctc atctagggct gtcacatcat tttccagagc aaacgccaaa tcttctgcca
    19981 cagacaagcc aataaactgc ccatctgtat cctgcaaaac tgtgctaacc agatgagact
    20041 tatcatagat gctcatatca aaggctactt gaccctttat caaaaattct ccatatgtct
    20101 gacccttgta aatattggga ataatcccat tcaaacactg acccaaggta gatttacctg
    20161 acccagatgg tccaacaatt aagactttct ctcccttgta aatggtcaag tctatccctt
    20221 gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa atccttccac tcaattatag
    20281 cttctttcat cttactctct tcattcgctt cttagacttc tattttatca taaatcaagc
    20341 ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa agattcctat cctagcttac
    20401 ttgcctaact aatctataaa catcgaaaaa gactagttgc ccagccttcc ccatcatttt
    20461 atactcttcg aaaatctctt caaaccacgt cagcttcgcc ttgccgtagg tatggttact
    20521 gacttcgtca gtttcatcta caacctcaaa accatgtttt gagctgactt cgtcagttct
    20581 atccacaatc tcaaaacact gttttgagca acctgcggct aacttcctag tttgctcttt
    20641 gattttcatt gagtattagt cctttttcaa acttcctgca cgagtttggg ttcctgcata
    20701 ggcaagtaag agaagagttc ctgcaatagc tacagataca ccattggcaa ttcccgcaac
    20761 aatcccttgt gcaaatactt tttctgccgc ttcttgataa atcacaacat ctccaagtgg
    20821 tgccaagaca ccccaaacaa gggcatttgc aagtagttga atgaggttaa aaataagaat
    20881 atctttccag tcaaaaacac cattgatcac tcgaacgtac tttctaaaaa gtcccacaac
    20941 tagaccaaag agtccgctag cgataatcca agtccaccat agaccataac cagcaagaga
    21001 gtccttgatt gcatgaccaa tcaacccgac aagcaaaccg ataatcggtc caaaaataat
    21061 agaaagtagc gcttgtaccg catactgaag ctggatgctt gtatttggaa caggggttgg
    21121 aatgttgatc atcccgatga cgacaaagag ggcagcgcca attccgacag caacaacttg
    21181 tttaattgta aatttgattt ccatactatt ctcctatttt atccttctat tttctttatt
    21241 tcaatggtcc aagatgaacc gacacctaca ttataggcct tggcaaagga accttggttg
    21301 atagccaaac ctaaacgata gagagagttg atgtaaagga tgggttgccc aattctcaca
    21361 tctgcaaatg atttgccata gacaacctga ttttgataga ccagcatatc agcatgatag
    21421 atggtcactt caaaacgatc accaaattct ggttccagct tgtaaaattc ttcccgtgtg
    21481 atagaggtcc aaagcgaacc gaaacgcaca tccagaatat caatggctcc cttcaccaga
    21541 tgatcttcta tgatggtcgc tacgactgga agctctacaa tctgttccac actgagctct
    21601 ggccctactt cctcaaaagt aatgtgacca ctggccagtt tagcaccagt ataggcatag
    21661 acatcacgac cgtggaaggt ataagaatgc tctgtgtttt gacgcctatt ggccacctca
    21721 gaaatctcac gaatggctac aatgccaacg tgtttcttga taaaggaaag cgtcccatta
    21781 tctggcgtga caatgtattg attttttgca gtcttggcaa ctacactctt acgtttcgaa
    21841 ccgacacctg gatcgacaac cgatacaaac gtcgttccct caggccagta atccaccgtc
    21901 tgaaagagac gatagctccc ctcaaaaata ttataaggcg tgatatcgtg cgtcaagtga
    21961 tggattttta aggttggaga ctcttctaaa gccactccaa tcatagccga caccgcacca
    22021 tcaaccagac caaagtctga ttgtaatacc agtaaattat tgttcatttt atctccttgt
    22081 atatccttta tcataccata tttcagagaa agtcgctaat agctatttca attggttagg
    22141 gtatagtttt accttatagc gaattttcac taaaagctct tgttattagc tagtaggtgc
    22201 attttttctt gaaaaagggt atgatagtta catcatgaaa aagtaggttt tattatgaaa
    22261 attatccttg tcggaggggg aaaagttggt tttgccctct gtcgctcctt ggttgcagaa
    22321 aagcatgatg ttttgctgat tgagcaagac gaagctgttc tcaatcatat tgtcagtcgc
    22381 tttgatatca ttggtatcct tggtaacggg gccgattttg ccattcttga gcaagccagc
    22441 gtccaagatt gtgatatctt tatcgccctg actgagcacg atgaagtcaa catgattgca
    22501 gcagttctag ccaagaaaat gggagctaaa gaaactatcg ttcgggtgcg gaaccctgaa
    22561 tattctaact cttatttcaa ggaaaagaat attctcggtt tttctcttat cgttaatcct
    22621 gagctcttgg ctgcccgcgc tatcgcgaat atcattgact tccccaacgc cctgtctgtc
    22681 gaacgctttg ctggtggacg cgttagcctc atggaatttg tcgtcaagtc caccagcggt
    22741 ctttgccaaa tgcccatttc tgattttcgt aaaaaatttg gtaatgtcat tgtctgtgcg
    22801 atagagaggg atcatcaaat tatcattcca agcggtgaca tgactgtaca ggataaagat
    22861 agaatctttg tcactggtaa ccgtgtcgat atgatactct tccataatta ttttaaatca
    22921 cgcgccgtga agagccttct catcgttgga gcaggtagaa ttgcctatta tctacttggt
    22981 attctcaaag atagtcgtat cgatacaaaa gtcattgaaa tcaatcctga aatcgccagc
    23041 ttctttagcg agaaattccc aaatctctac atcgttcaag gagatggaac cgcaaaagat
    23101 atcctgctgg aagaaagtgc tcaacactat gatgccgttg cgactctaac aggagtcgat
    23161 gaggaaaatc tgattacatc tatgttcctt gacagggtag gtgtacagaa aaatattact
    23221 aaggtcaatc gtaccagtct cctcgagatt atcaatgcgc ctgatttttc aagtatcatc
    23281 acacctaaaa gcatcgctgt agatacgatt atgcacttta ttcgtggtcg agttaatgcc
    23341 cagtattcag accttcaagc catgcaccat ctagccaatg gccaaatcga aaccctgcaa
    23401 ttccatatca aggaagccaa taaaatgact gccaaacctc tttctcaact gaaattgaaa
    23461 aaaggggttc ttattgcagc cattattcga aagggcaaga ctattttccc aactggggag
    23521 gatatgttgg aagttggaga caagctccta gtaacaacct tgttgccaaa catcaccaag
    23581 atttatgact tgattgcgag gtaagaaatg aataaaagta tgattcgtta cctcctttca
    23641 aagttacttt tgattgaagc tgttctcctc ttggttcctg tggctatcgc tgtctattac
    23701 cgtgaatcga gccaagtctt tacagccctc ttttcgacca tagggattct cgtattgtta
    23761 ggcggttcag ggagtttaca gaagccaaaa aatcaacgga tttatgccaa ggagggagtc
    23821 ttgatcgttg ccctctgttg gatcctttgg tctttctttg gtggtctccc ctttgtcttt
    23881 tctgggcaaa tccctagcct tattgatgcc ttttttgaaa ttagttctgg gtttacaact
    23941 actggagcaa gtattttgaa cgacatttcg gttctcagcc gttccctcct cttctggcga
    24001 agttttaccc acttgattgg agggatggga gtgcttgttt ttgcacttgc tattatggac
    24061 aatgccaaaa atagtcacct agaagtaatg aaggctgagg ttcctggtcc tgtctttggt
    24121 aaggttgtat ccaaattaaa aaacactgcc cagatcctct atctccttta catagccctc
    24181 ttttccctct ttgtcatcat ctattatcta gccggtatgc ctctctacga tagttttgtc
    24241 attgctatgg ggacagcggg aactggagga tttaccgtct ataacgatgg aattgcccac
    24301 tatggtagct cactgattac ctatctggtt agtataggag ttttggtttt tggggtaaat
    24361 ttcaatctct actactacct tatgctccgt cgggttaagg ccttctttgg agatgaagag
    24421 cttcgggctt acttggtcat cgtgctggtt tctacaggct tgattagcct caatactctc
    24481 tacctctacc cagggttttc aaagagcttt gaaatgacct tcttccaggt ttccaacatc
    24541 attacaacaa ctggttttgg atatggagat attaccaact ggcccctctt ctcccagttt
    24601 atcctccttt tcctcatggc aatcggtggc tctgctggat caactgcagg tggactcaag
    24661 attattcgag gcctcatcct ttcaaaaatt gccaaaaacc aaattttgtc aatcctatcg
    24721 ccccaccgtg ttttgaccct ccatgttaat aaaatggtga ttgacaaaga tacccagcat
    24781 aagattctca agtactttgt catctatgct atgattttgc tagcgcttat ctttattgtc
    24841 agcctagata gcaatgattt tctggtcgtg accagcgctg tctttagctg tttcaataat
    24901 atcgggccta ttctaggaac cacttctagt ttctcaatct ttagtcccat ctcaaaaatt
    24961 ctcctctcct ttgcaatgat tgcagggcgc ttggagattt acccaatcct ccttctcttt
    25021 atgaaaagaa cttggtctaa gagataaaat acaaaatccc tctttttaca attgtgaaag
    25081 agggattttt atattaaaaa gggggaacgt ttttaaatcc aagcctgtct gtaagcaaag
    25141 ttcttactca aataaaagat ggaaaaactt actacacagc ttggtaatgc tccaatacaa
    25201 attgtaaggc tttacttgga ttctttgtta aatgaatata ttccattcct ctggtagcaa
    25261 ctatctgaat acctaatctt tctgcatcca ccttcatctc tctataataa ctccgaactt
    25321 gtggagccag aataattaaa tcataaacac ccataatatc ataatgagct ccgtacgctc
    25381 ctgaattcgc aatcactcta acttctgcta attgagcgcc ctcgttaatt gcattggcta
    25441 attacgcact tgttccagac cctgcacaaa gaaccagtac tttcaactcc ttacttttta
    25501 ttacatctat ctcaccaggc attatttcac ttgtatcctc ctctaaaata atatcatttg
    25561 agcttgcaat atctacaacc tgtagtagat atctcgtatt tagacaatat gaaaacaaga
    25621 cgacttccat ataggaaacc gccttctctc tatgttgagt gatttatatt aaaataactt
    25681 ttcttctagc tgcattttat tattataaaa acattcatca taaccctgaa cttaaataac
    25741 gatttttatt caagatacat actcctagaa taaactttat atgaaattct catttttgtt
    25801 tttacaattc tccttagtta aatcttgttt aatatatgtt ttacatatag tatttagcgc
    25861 cacatagtac tgaactctct ccaaaaacgg ttattcctct ttgaataggg cgttatcaca
    25921 agaaaagcat ctccacgttt caacttcata tggctcaaaa acaatcaatt gatgctaaaa
    25981 cctgtaccta gatgtttcgg ttcataaaac catgaaactg taaaagtgaa tgaaattgat
    26041 agcgatagtc aaatcaagag gcatcataac tctaaaaagt cacaatatat aagttcatcc
    26101 tcggaaaaat atcattctaa ttgttgaaat gcctacatga aaagaaacgt caaatgctca
    26161 tgaaacaacg aatacaggta tcaaaactat gacaaaacaa gtccctaaat ttactaaaga
    26221 cactgctcaa ctttacacct gtaagtggtt gttgtataat aaagttacaa agatgtacga
    26281 ccacactgtt gtaaatcata gtgttcgcga atatattact gatagcattt ctacaaatac
    26341 aattgaagag actggataga ctttaaacga aatatgtcag tgttttggca ttcctagcct
    26401 tcatatcatt taaagaattc tatagacaaa atttttccca atacagacac tcgtaacaac
    26461 tgcttcattt ttctaccaac atatttagga acaggataag atacaagagg attaatccat
    26521 agatcagttc tataccaatc taagacaaat aagctaaaaa aacgattgat aataagcaaa
    26581 tagattccaa attttctcta tctgctcatt ttaataaaca atactagtgt aactatcctt
    26641 ccagtcagaa acttgtcaaa tcacaccgaa aactcttcta aaatttatct cgttaggcaa
    26701 tcaagcaaaa actcgacgat agtacaaaca ttatcataca gaattgactg cctaaattat
    26761 atactttagt aaggttttcg gataagaaaa aaggttcatt ttacatttct aaacattctt
    26821 ttctaagatg aaaaacagaa tttttcgatt gtgatttaaa gcaacaagaa gattttcagt
    26881 atcatcctat agatacgagc taattaagaa aaactacatt tttgaatata aactacaata
    26941 atataaacta aattttatag gaggaagaca atggattggt acgattatat gatacaggca
    27001 tccaaacaat cacaattcaa cgcaagccat tggtttcgct atttgcgaaa agttattttt
    27061 gaagactatt cttatttaac aaaccaagat gtagaaaagt tgctagactc caaagaacta
    27121 acccgttttc aaaaaattag cttgaagtat gcctttcaag agcatactcc aactcataaa
    27181 tatgtgattt cattaaataa acctgctaag ttaaccaatg ttcaaaaatt gatggagaaa
    27241 tacaaacatg gataaaatga aaccggtctt ccaagcccta aataagaaat taattcagga
    27301 aaatctgact ttaacaatta tggttatgtc ttagaatatc atggtttacg taccacacaa
    27361 gatgttgatg ctttttatga ccaaaatcag aaaatcaatg aaattattgc tcgtgtagga
    27421 aaacagttta atcttaacat ccacgaagag ttatggctca acaatcatgt tgcaaagcaa
    27481 atatgaacaa acaacctccc ttaagtttat gcgaatcctt gtactcattt gagaatctga
    27541 ccgttttagt agtccctatt gagtatgtgt taggaatgaa gatgatgagt atcagagagc
    27601 aggatttgca agatattggt gcaattatta aatacaaaaa ctttcattca ccattcgata
    27661 cctttaaata tttaaaagac atgggatttg atactattga cctctctgtt ctattagaag
    27721 gttttagtta tgcttatggt atggattggt tagaaaaatt ttttaaagaa aatcaagata
    27781 aacttcgcga attttattaa cagtatcaaa caagatgatt gtcaattagc cagtcatctt
    27841 atttttatga tgaaatgaaa taaaatcgga acaaatcact tagagaattc cagtcaattt
    27901 ctagcactgt ttgagccgtt tcagcggact atagtaaaat gaaataagaa taggacaaat
    27961 cgatcaggac agtcaaatcg atttctaaga atgttttaga agtaaaggtg tactattcta
    28021 gtttcaatct attatatttc agattcggtc cactattcct tcccaaaaac attgcatatt
    28081 gcgccgaagg aattgctcat actatcccaa gcacaaaacc ctcagtcgtt tgaccgaggg
    28141 ttccttttca ttattcaaaa acttgattag ctcaatgcat ccaaggcatc atccattgaa
    28201 agaacttcgt ggaagacacg ttgtgtcaat tcagtttttt gttctggagt gaggtattta
    28261 gtatttacac agtatccaga gatacgtacg ataacgtctt cacctgacat aattttttcg
    28321 taaacatcgt tcaagtccat aacgttcaag ttaacgtgtt gtccaccgtt ttcgaagtaa
    28381 ccatcaagga ttgttaccaa gttatcaact tgttcatcac gagtcttacc aagagcgcga
    28441 ggtgatactt gtgtagtcaa tgagataccg tcagctgcat aactaaagtc aaggctagaa
    28501 agtgagttca agttttgcaa ccaaccacct ttagctttgt tagatgggtt agcacctggt
    28561 gagaagaatt caagtttaga caagttcaca gaaccatctt cgttgaggta tacacctttg
    28621 tgaactggtg agttaccagt ttgtttagag taagcaacgt tagatgtgat tgtcaaaagt
    28681 gatactgtag cttctgcgtc tttgtatagt ttgtggctac gtagacgagt tgtgtaagct
    28741 tcgatcaacc attctgccaa ttcgtttgaa cgtgggtcat cttcacccca gcgtgggtag
    28801 tcaccgattg tttcgtaatc gtagatgtag ccatcttcgt cacggattgg tttaactgta
    28861 gcgtatttga tagctgacaa tgtatcaaca gtgttagcaa atccacagat accgaatccc
    28921 atgttggcac gttgtttagt tggcaagaag gccatttgaa cagcttcgta gttgtaccta
    28981 tcagtcatgt agtggatgat gttcaaggca tctacgtaag tgtcagtcaa ccagtcaaga
    29041 gatttttcaa agttcgcttt aactgattcg aattcaagaa cttcgtcacg gattggttcg
    29101 atatcaaata ctttgtagtc tttgtgaaca tcgtcgtaac caccattcaa accagtaaga
    29161 agggctttaa gaacgtttac acgagcaccg aagtactgga tgttgtggcg ttgttcttca
    29221 ttttctggat caagtggaga cacacagcat gagatacagc tcatttcacc atatccgtct
    29281 ttagccattg ttgttacacc ttcgtattgg atagaagagt gtttgtggct catgtgcata
    29341 cagtagcgac ggaagttgta tggcaatttg tcagtccaaa gaactgtcaa gtttggttct
    29401 ggtgagttac cgatgttgtc aagagtgttc aagaaacggt agtccatctt agtaacacgg
    29461 tgacgaccgt cgttacccat accagccata gaagttgtga taaaggttgg gtcacctgag
    29521 tacaattggt cataagcttt tgtacgagca aatttaactg tacgaagttt cataacgaaa
    29581 tcatcaacga attcttggat ttctgattca gtaaatgtac cacgagcaag gtcacgttct
    29641 gcaaagatgt ccaatacgat tggtacacga cctagagatg tagcagcacc gttaatcaca
    29701 cggcagacag ccatgaaagc aatgttaacc cattggattg cttctttcac gttcatcgct
    29761 ggtttgcgaa catcaacccc gtaaaggtca cccaggcgaa caacttgttg caatgcttgg
    29821 tattgaaggt ttacttcttc acgaagacgg attgtttctt catcgatttc tttgattgca
    29881 ttccagtcat ttactttttc ttgcatcaag tagtctgcac cgtaaagagc aagacgtgcg
    29941 taaacaccga tgatacgtcc gcgtgagtat gcatctggaa gaccagttac agtgtgtgcg
    30001 tgacgagcgc gacgaatatt tgaagtgtag gcacggaaaa taccgtcgtt aactgttgtt
    30061 acatatttag tgaagatttc gtgaacagct gggtctggtt cgtatccatt ttctttcaaa
    30121 gtagtttcag ccatacggat accacctttt ggcatgaagt tcaatttgaa gagttcatcg
    30181 ttttggatac cgaagataac ttcattttct ttgtcgataa atccagcagg gatatcagcg
    30241 atagatgttg gacgagtgtc cattgggaaa cgagtttctt cgtagtgtgc tttagtttct
    30301 tctacaattt tcttgatgtg aagtgaacgc tctgttggtc ctgcaaggaa gctttcgtct
    30361 ccatcataag gtgtgtagtt agcttgtaca aagcgtgata cacttgcttt ttctttccaa
    30421 tctacgcctt tgaagccttc ccaagctttg tcaaaaatat cttgtgcttc aacaactgtc
    30481 ttaacaacca tattaatgtc ctcttttttc tagtaacagt catctgttac attcatgaga
    30541 caagtatacc atatagtaac cgattttaac aagtgaaaaa tccctatttt tacactttct
    30601 tttctaaaac agtctatatt ttatttcaaa ctgtattata tttttgaaaa aataaagtcc
    30661 ttttttcttt ttttcagaaa aaagggtata ataaaagaaa ataagcagta acactcaatg
    30721 gaaatcgaaa agcaaactag gaagctagcc gcaggctgct caaagcactg ctttgaggtt
    30781 gtaaatagaa ctgacgaagt cagctcaaaa tactgttttg aggttgcaga tggaagctga
    30841 cgtggtttga agagattttc gaaaagtata aaaaggtgct aggcatgttg atttttcctt
    30901 tgctaaatga tttgtcaaga aaaatcatcc atattgacat ggatgccttt tttgctgcgg
    30961 tggaaatcaa ggataatcct aaactcagag gaaaacctgt cattattgga agcgaccctc
    31021 ggcaaacagg tggacgggga gtcgtttcta cctgtagcta tgaggctcga gcttttggtg
    31081 tccattctgc catgagttcc aaggaagctt atgaacgttg tccccaggcc gtctttatct
    31141 caggaaatta tgagaaatac aaagctgtgg gactccagat tcgagctatt tttaagcgct
    31201 atacagattt gattgaaccc atgagcattg acgaagccta tttggatgtg acagaaaata
    31261 aactcggtat caagtcagcg gtcaaaattg ctcgcctcat tcaaaaagat atctggcaag
    31321 aactccatct aactgcttct gccggtattt cctataacaa gttcttagct aaaatggcga
    31381 gtgattatca aaaaccacat ggtttgacag tgattctacc tgaacaggct gaggattttc
    31441 tcaaacaaat ggatatttcc aaatttcatg gagtaggaaa aaagacagta gaacgtcttc
    31501 atcaaatggg cgtttttact ggtgctgatt tacttgaagt tcctgaggta accctaatag
    31561 accgttttgg tagactaggc tatgatctgt atcgaaaggc tcgtggcatt cacaactctc
    31621 cagtcaaatc caatcgcatc cgtaaatcaa tcggcaagga gaaaacctac gggaagattc
    31681 tccttgctga ggaagatatc aaaaaagagc tgactcttct atcagaaaaa gtcgctctca
    31741 atctacatca acaagaaaaa gctggaaaaa ttgtcatttt gaaaatccgc tacgaggact
    31801 tttcaactct taccaaacga aaaagtcttg ctcaaaaaac acaagatgct agtcagataa
    31861 gccaaatagc cctgcaactc tatgaagaat taagcaagaa agaaagaggt gtccgcctat
    31921 tggggattac catgactgga ttttaaagct caatgaaaat caaagagcaa actaggaggc
    31981 tagccgcagg ctgctcaaaa cactgttttg aggttgcaga taaagctgac gcggtttgaa
    32041 gagattttcg aagagtataa aaccttgaag agttgcccct tcaaggtttt tcttatacaa
    32101 ataaacggac aaaactgtaa agtagcaaaa cactaccaag cacgatacgg tatttaccaa
    32161 aaagggtgaa gtcgtgtttt ttcacatagc tggtcaagaa gcgaatagcc accatgctga
    32221 ccgcaaaagc tactcccatc gcgaccaaga gcaaaaacaa ttgcccaaag ctcaagagtt
    32281 ctccggcttt cacaaatttg aaaatcttta aggcactagc tccaaacata acaggaatcc
    32341 caagatagaa ggtaaattct gtcacaactg aacgactggt tccatttaac aaaccaccga
    32401 caatcgttgc acctgaacgg ctagtccctg gtaaaagagc aagaacttgg aagagtccga
    32461 tatagaaagc ggtcgtataa ggaagcttgt ccaactctgt tacacttggc tcgatagcac
    32521 gcgctttatt gcgcttttcc aaatagatga aggcaacccc gtagataatc aacatgagag
    32581 caactgaaac catgttatgg aagtgggtat caaaccaatc atcaaattta aagacaccaa
    32641 gtaaaggtaa agtagcaatc aagaccttca accatagtct ccaagtctta cgaacttcct
    32701 gtttgtcctt agtcggttta aaaggattga gcttgttaaa ataaatcacc ataactgcta
    32761 aaatagcacc aagctgaatc acgacattaa acatggacat aaaggcttca ttttgatttt
    32821 ggtattggat gaattcctct gctaaaatca agtgacctgt actggaaatc ggcaaccatt
    32881 ccgtaattcc ttcaacaatc ccgaagaaga tagattttaa aatttcaata agatacatag
    32941 attactccct atattataat tagcgcagtt agctactgcc aaagcccaag tggtatactt
    33001 ggaataagcc actgtggatt agttcatttc ctccaatcgc ttgacgattt ccgaaaggat
    33061 ctaaccacag cttttgtttc aattggtaat gagtttgata acgcatagac gttttatctc
    33121 gtctaaggta acaaggcaaa aagttcgtgg ataaccaagt agacttgaaa tactatatct
    33181 ggaggtactc ccatgcttta tgtgggcatt gatatcgcta aaaataaaca cgatgttaca
    33241 gccttgaatg ttccaggaaa aactgttctt aaaccactca ctttttcaaa taataaagct
    33301 ggttttgaac tcttagatct gtctcttcga caactcaacc aagactgtct catcgctctt
    33361 gaaaataccg gacattatgc ctttaatcta ctgaacttcc tgcatgaaca aggatataaa
    33421 gtttacacct acaatccttt gctcatcaag gaatttgcca aatcattatc acttcacaag
    33481 actaaaacgg ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat
    33541 cgtgaacaat ttcaacacga taatcggcaa gtagaactaa aaatactggc tagacatatt
    33601 catcgtctca agaaaaacag tctgattgga aagtac
//
LOCUS       DBERCW010000025        28504 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.025, whole genome shotgun sequence.
ACCESSION   DBERCW010000025 DBERCW010000000
VERSION     DBERCW010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 28504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.025"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1452)
                     /locus_tag="ACL72M_001370"
     CDS             complement(<1..1452)
                     /locus_tag="ACL72M_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGS0716487.1"
                     /translation="MIYLTEGNTPLNEAYNDEIVHLGNNTYQLTFRFPTSDTKWELLK
                     EETFLTADDLHGEQDFYIFEVEKQQGYIQVYANQVISLLNNYIVSSIEVDRVSGTRVL
                     SAFAGSITRANPFSFFSDIDDRHTLNIKDKNAMEVLAKGKHSILGQWGGDMVRNGYNL
                     RLLKNGGSENESLFMYKKNLSSYQHKTSTKSLKTRITFKTTVKGEGENAVDHDYMVVI
                     DSPLLGNYSQIYEDVVEVNDQDVTDEASLIEYGKQYFRTSMCDMLEDNLEISVVGQSD
                     VAVQMFDVVSFYHEWYGLDVRKKITKYTYSPMAKLLKSIGFGTFQSSLANAIGGIVND
                     AVLNESRNLHQIFEERLKKEIANADRAFDAEFSKREKTITDAIELAKAKAEEVKQELS
                     DTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQTT
                     SAQTALSGDLDALKRTIANDIRPKQAQAEAEIAK"
     gene            complement(1449..2147)
                     /locus_tag="ACL72M_001371"
     CDS             complement(1449..2147)
                     /locus_tag="ACL72M_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGS0716488.1"
                     /translation="MFYMIINGFNTSTIPHCVVTDFGQVEAAKPRVVEDANLYGANGS
                     YRVLDGGYESYERTFSFYIPKLLDVSTIVEKFQPKDNVLEFSYQLGSVFYADFIGATY
                     SPHGMHAWKLEIKLNMQPFRYQKNVAPLIFTASGNINNPGSVYSEPVIEIEGDGDISL
                     TIGRTTMHLTVRRKVTIDCRHKKQNIYNADGAVQNTLRKRGGFFELAVGNNSLVFTGS
                     VRKVTVRPNWRYIL"
     gene            complement(2147..6322)
                     /locus_tag="ACL72M_001372"
     CDS             complement(2147..6322)
                     /locus_tag="ACL72M_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGS0716489.1"
                     /translation="MASGTPLGAMYIELGLDVSNFNPTLTGAKNAVKYFQNTVRSLDS
                     TLKGNEKNASLLQAKYKTLGQAIDSQRKVLDEMKKSFDKLEPGTAKFDKAAADIQREN
                     AKLAAMEGQLRGVEKALQDVGRENSWSGKMDALSEKFAKGGKKLRAMGDAMKPVSAAL
                     LAGFTLSTKKAIDFESQMNTTKSLLADTIPTADELNSTTQKLGESSKNWAKQYGISTA
                     SINEGMQEIIKKGFDANQTIEAMPAILDAAKASGEDFNTVMNATTNILQQFGLSTQDT
                     ERVTNSLTFVANKTAAGFADMGAAMEYVGPVAKNVGMDLEETAATVGLLSNNGIAGEK
                     AGTALRGALTRLLKPSKQNANAMAKLGFSAEEFRSGAIKLPDILDRIKKNTEGMTDAQ
                     KSALIATAFGTEAQTAMNILVDQGGDALRNLANETKGATTYTKDLANELSKSSKNGVE
                     RFKSSLEVLQINIGQKLLPLLTPVIEKVNQFIDWLSKAPPAVQSLAVGIGGFLALGYP
                     LLNFLGNGATALSILIKHAGKLGGLLKGGIGLAKLTERAGKLKGLLQGGIGLAKVGSE
                     ATVLAEGAGVAASSSGLLSGAIGALTNPIGLLVGGVALLAGGLVYLGHKKDEARIKAE
                     EFGSQLSDTARKELRDFQSKVDETSKAVANFGTHAGDAEKVSGAFKKLYDEIAAGAEK
                     SNQRMQELTGKWGLSEEDLAKAREKNAQMVSNAESMMNKINDIYQRHNGDASKFSQEE
                     KEIILNNQREMIKTRISMMNLSAEQQKAALQALNGEIGSLNETQLKHTRDVLKKSLDE
                     EKQLYETSKSELKELLEGKVIDQETYNKKLQTLETNHQQTMEALGTKYYQVMQNLDAK
                     VKARTGQSWNYWEEAKKVLEEYGLSYEVIGQKAAEASQKMGESHSILAKYTSEMSKET
                     KEANDAWSLLVGNINENGNFEIKSNVKEVIGEATKSAEGWEQLQFIVKSANINSNARV
                     MIAEALVESGKWSTMTLEEKQLIVQNQAGLQAIFDSENHLRIWNSMPAEVKQLLLENT
                     DVMNKAEEASKALYNYDALTPKQKELLATDENFRKAVARSTDTLTTWNATTPFTKDLK
                     LDPTNVLNNGQLSIDKIMVWNLSNPETKSLNATDNTSEAVDSAKASVNSPKQEKPIDL
                     LAKDQTAGVRNETSAAINAIKQNNPVDILAKNSTSSTVSEVKSGVNSIQDKTVTISAR
                     DNASGVLAGIRSWIIRVTGDFFTNVFASRHAHGTNYHPGGLAMVNDQRNSTYKELVTL
                     PDGRSFIPEGRDVLLPLPKGAKVLRADKTKRLMREMGVPKYAAGVGIPSDAKFLREME
                     EAQAKIVVQAKGETNSKDSDKVVSEIAILRASMEKILTAILEKPSDTYLDADKISMSV
                     YQRQGAIYAREGM"
     gene            complement(6379..6609)
                     /locus_tag="ACL72M_001373"
     CDS             complement(6379..6609)
                     /locus_tag="ACL72M_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716490.1"
                     /translation="MSRKEKARRRYWFWFTIFILYLAFGLYCICTNFGDTLGMLLLSP
                     FIFASLPLYAYLFLGLFIWAFMSLAMDDFYKE"
     gene            complement(6858..7151)
                     /locus_tag="ACL72M_001374"
     CDS             complement(6858..7151)
                     /locus_tag="ACL72M_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716491.1"
                     /translation="MAKVQFTIKNDKGEDVLKKSKEITTRDYRDYLVMNDSLTSDLSE
                     VEKLDKQLGFIASLFDDVTVEQLLEYTDFAKVISIFTDIYAHLVGDVDPKEKS"
     gene            complement(7200..7796)
                     /locus_tag="ACL72M_001375"
     CDS             complement(7200..7796)
                     /locus_tag="ACL72M_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HGS0716492.1"
                     /translation="MTVKGTALIGLKSVTIRVHDGQTPTVGQNLFTLEGKDNEGATQT
                     ARVTGLSSDPVKTYGSNVAYHVSNRGVGDVKVEMGLLDVPLALYTNALGYGDDDGIYY
                     FGADTVAKNVSILIESNTADGEPVYYGFYKGQLSMDAIDFETIKDKANELATTNVNFA
                     ATASSDTATKGRYGAIVYGSDAEKLKKLKGQLNMAAAG"
     gene            complement(7813..8193)
                     /locus_tag="ACL72M_001376"
     CDS             complement(7813..8193)
                     /locus_tag="ACL72M_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716493.1"
                     /translation="MIKDKLTELYDALEEDESLSGISIKSFERPESLGDDETSIVIIP
                     VGPPMQTAHGSNTSLAKTFLYQINVESTNRVECKELQGRIEKIMEEQGFYQTEGGLEQ
                     WIPDIKRYVDVRTYRGMSALYEKY"
     gene            complement(8193..8591)
                     /locus_tag="ACL72M_001377"
     CDS             complement(8193..8591)
                     /locus_tag="ACL72M_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716494.1"
                     /translation="MSSGANLKGFDDILRNIEARLGEPVVRRNVNRALKETVEEFEPT
                     FKRAMAVYADTGKTVGAVVHGNVTGTSSGVPMVKLGFKSPRWTLIHLNEFGYAKNGHP
                     RGFGVMRRFFEASKPVFKSKVGMKLKQEFL"
     gene            complement(8584..8973)
                     /locus_tag="ACL72M_001378"
     CDS             complement(8584..8973)
                     /locus_tag="ACL72M_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HGS0716495.1"
                     /translation="MKRSEGPSYRYKKPESQNGDLRTPLTFYTSKIKKGVDGRDVSYE
                     KAFYTMGQTYSPSMKDVEIATGKAMKAKMTLKIRDPLTDYQPENRHFVEVGDIRLVGK
                     KWQIIDVRPDYDNRDFLIVLIGGGRDV"
     gene            complement(8960..9148)
                     /locus_tag="ACL72M_001379"
     CDS             complement(8960..9148)
                     /locus_tag="ACL72M_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716496.1"
                     /translation="MIKVLKEFYDLKEGVLRQVGGRFEATEERFAELKEHLPGYVELE
                     KSSRSRSSKEVVSVNEEE"
     gene            complement(9141..9431)
                     /locus_tag="ACL72M_001380"
     CDS             complement(9141..9431)
                     /locus_tag="ACL72M_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HGS0716497.1"
                     /translation="MEIEAKLHSLLDPFKERMRIFHSGEDANLSRMLESSQMVITRLV
                     GSGNIHDHQIRELILERARYVYNDQVEFFYENFKADILALSLDKIEMEDSDD"
     gene            complement(9445..10560)
                     /locus_tag="ACL72M_001381"
     CDS             complement(9445..10560)
                     /locus_tag="ACL72M_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGS0716498.1"
                     /translation="MMKLGNEFTTARQNFMNAVETGAPMEEQNKLYNEMIEALTDKLQ
                     DDAREAARKEIATMNPYDAQLTAEAREFFNNIEKLPPKGIEKLFPQETIDRIFEDMVA
                     ARPLLQHIGLRNAGIRLKFLKSSRTGQAVWGKINAEIQGQLKQEFAEEEAIQSKLTAF
                     VVIPKDSEKFGPAWLQSYVSIQITEAFAAALEAGYLNGDGDKQPIGLSRTLTGTVESE
                     KVTYAEKQAQKKPLTFADSATVVKELTEVYKYHSTKADNTTPVAVEGNLVMVVNPVDA
                     WDVKKQYTSLNAQGVYVTAMPYNLILVESVAQTSGKVTTFVKGRYDAFVGGGIEFGRF
                     TETYALEDLNLYTAKQFAYGKAHDEKTAAVWTLNIGK"
     gene            complement(10579..11301)
                     /locus_tag="ACL72M_001382"
     CDS             complement(10579..11301)
                     /locus_tag="ACL72M_001382"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HGS0716499.1"
                     /translation="MTIIQIKGAIVSNDDRWFYDWIDMDATAPKDIVLPTTGEDVEVH
                     INSGGGDVYAGSEIYTALRAYQGHVTVKIVGIAASAASVIAMAGDQVEISPTAQIMIH
                     NVSAGVRGDHKALLHEAGVLEGFNKSIAYAYIDKTGKALDDLLDLMEGETWFDARSAV
                     NHGFADKVMFESQEAPVLVASQTPVIPRDFIEKIRSAMTPDVELLADLVRDRLNNSLL
                     IPEDKKKEDKTAEPVGLGRFPF"
     gene            complement(11282..12430)
                     /locus_tag="ACL72M_001383"
     CDS             complement(11282..12430)
                     /locus_tag="ACL72M_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGS0716500.1"
                     /translation="MGFLNLFKRDAPDVGFDFEELERMLGRLQLKSLAIDKSAEFVAR
                     IFAKSEFRYMVENHHVASDWDYILNVRPNKNESASEFWQKVIYRLLTKNEVLIVLSDD
                     KQLLVADAFTRRRYALYDDTFEMVSVGDYIFQRKFAMSDVIFLQYNNNRLQEYVSDLF
                     SDYEKLHTRLVEALARNNQIRGVLATKANGTFDDDKRKKLQRYADNLFKSFTSKTVAI
                     VPTMDGVEYSELTNTVGTTNLSVEELKKLRRQFDDEVADILGLPTALMHGDMADLSNS
                     QKMFNSYCYESLVKKVGDALNHAMVSSAGYANQKKFVIFGEGGLDKFALAENIDKLIS
                     SGAMTRNEVRLELGLEAVPGGDSFLITKNYQGENEIEKGGNEDDNHSD"
     gene            complement(12487..14127)
                     /locus_tag="ACL72M_001384"
     CDS             complement(12487..14127)
                     /locus_tag="ACL72M_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGS0716501.1"
                     /translation="MISHPLVDDYIKMAESGEIVVNKERKLLFKIIKEKIYPRDDLYF
                     DNDLIDKFIRFAEKNFFPLAKYQLFLTPFIFLFRKEDGEPHFDEYLYTLARGGGKNGF
                     MSARSSFFISPIYPIRDYDVTITANSEKQGKVSFEEVYETIQRRGLEDHFYLTKMSIT
                     GRANNSVFSFRTNNPKTMDSARDGCLEFDEIHQFEDDKAVKVQRSGLGKIAHARTFYN
                     GTNGYVREGFYDKLIEKSMQILNGEVDDFRLFPFICKLDSADEVDDMKKWPKANPMLD
                     ESTPYAKRLLARTKADYDDLELEPSGRQEFMTKRMNLPEADLEKDVTSREKLVACLRS
                     PGIDLLGKSCVAGFDYASIRDFASVGLLFKNGDEFIWKQHSFARKVFLKAFKLKAPIQ
                     EWADKGLFTIVDGPSIDPRLLVAKLEEWSKFYQIELVCADGFRMDLLKPLLEEAGFEY
                     EFLRNPGAIQSKVAPIIEDGFANERFVFENDNSMIWYTDNTYIKEDKDGNKRFLKKEP
                     VRRKTDGFHALIAALYKRELVHESNVGEFLDMLDSWDF"
     gene            complement(14124..14462)
                     /locus_tag="ACL72M_001385"
     CDS             complement(14124..14462)
                     /locus_tag="ACL72M_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716502.1"
                     /translation="MEEYSEKNIKELENQLLSKIGYFSPRKKDAIQYEKVNRYLYLVR
                     LLYELKAKLHEDGLVITVHNGQQRFQKANSLIKEINTTSNQLLAIERSFDFEVENSPV
                     EKPTSGSDLL"
     gene            complement(14581..14877)
                     /locus_tag="ACL72M_001386"
     CDS             complement(14581..14877)
                     /locus_tag="ACL72M_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HGS0716503.1"
                     /translation="MIDVSTREERNQFYNSSEWRTIRRQALKRDHYECVWCRDEGKVT
                     TTNLEVDHIKELELYPEFALDIDNLRTLCKACHNKRHDRFDKNDRNFRKDEWWG"
     gene            complement(14874..15080)
                     /locus_tag="ACL72M_001387"
     CDS             complement(14874..15080)
                     /locus_tag="ACL72M_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716504.1"
                     /translation="MKGIIKRLFNKRTTKQKPLGKIVVGVEIENRSELKELTQQCCEA
                     IEHLNNCIDKLNKFELKVSTSIIK"
     gene            complement(15246..15812)
                     /locus_tag="ACL72M_001388"
     CDS             complement(15246..15812)
                     /locus_tag="ACL72M_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0716505.1"
                     /translation="MVVVEPIRNRDDVQLMIEWLTLHSAVKESDRQRNLMLFLSGVNL
                     GFRIGDIVKLKVKHVKGWHVQIVDEKTDKPTKRKMPKKFKNAMRQYIKDKKDEDFLFP
                     SRNGKHQHIKPNTAYKIIKRAAEEVGLENIATHSMRKTFGLFMYEQTKDVALIMDLLN
                     HSSQSISLRYIGKNQDSQDRAMTKFQGF"
     gene            complement(15899..16324)
                     /locus_tag="ACL72M_001389"
     CDS             complement(15899..16324)
                     /locus_tag="ACL72M_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000963208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HGS0716506.1"
                     /translation="MAIDIKKRLKALPYIDIKAKSKHQEIISLKSGILRGQQFDSMPK
                     SKSNKNQTEELNVLIIDKSEQLYKEIKQMYHERDELVQAIESLDDPVENIVMRLLYID
                     GLSWKEVQIKLNCSPATIQRAKHKALLKLSKMYDKNDSK"
     gene            complement(16328..16726)
                     /locus_tag="ACL72M_001390"
     CDS             complement(16328..16726)
                     /locus_tag="ACL72M_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HGS0716507.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIINEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMP
                     AVYLKGFGDGYAWTEYEEIIGNIYENPVRR"
     gene            complement(16738..17121)
                     /locus_tag="ACL72M_001391"
     CDS             complement(16738..17121)
                     /locus_tag="ACL72M_001391"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716508.1"
                     /translation="MNTIEKVKQWFIDRDLENGRVVGLMVLSSKRRIYKMKRLGIIIG
                     AVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQALGMDALLSFIWPVLSSKKESEEDY
                     SYAVKSSISKIITCAFLIWLASLFI"
     gene            complement(17118..18200)
                     /locus_tag="ACL72M_001392"
     CDS             complement(17118..18200)
                     /locus_tag="ACL72M_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HGS0716509.1"
                     /translation="MKFLDLFAGIGGFRLGMESAGHKCIGFCEIDKFARESYKAIHNT
                     KGEIELHDITAVSDESIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRRERTRRFFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAIKSNTIKQFGVLQPNFNQCGVVYETDGIAPTIRAYQGGGLEPKIIQRG
                     HGYNKGGEHDIAPTLTSNSYHENNHLSDGFRIRKLTPRECWRLQGFPDWAFDKAQEVN
                     SNSQLYKQAGNSVTVNVIAAIAKELS"
     gene            complement(18231..18518)
                     /locus_tag="ACL72M_001393"
     CDS             complement(18231..18518)
                     /locus_tag="ACL72M_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716510.1"
                     /translation="MTQTLEEGMKNKSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEERV"
     gene            complement(18518..19105)
                     /locus_tag="ACL72M_001394"
     CDS             complement(18518..19105)
                     /locus_tag="ACL72M_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HGS0716511.1"
                     /translation="MNKDLIETPRFNFFIGDEVLLKGKIVGFDVDENKCVENVVRLEY
                     GQTLNVPNNNIYITDDIVDKSKIKVVVPQFVADWYEENKDSFEFNVWDWIAFRDEAKK
                     SENREFNNWINNSRENPIQTLVNMHQFGYEVEEEKRYTVVTKATKQPLYYNAMDKKLF
                     FSMGGLATKFTRKQLEEVGVGWVFDCPGIEIEEVE"
     gene            complement(19098..19598)
                     /locus_tag="ACL72M_001395"
     CDS             complement(19098..19598)
                     /locus_tag="ACL72M_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HGS0716512.1"
                     /translation="MNKQELIKKLEERRTMTRNFQGYVVWWKDVKEIFEQLGEPQPVK
                     VPQFVADFIAEQKKLGHTLSYSIDASMSDIVAEWYWDNSELFALAWLNGYEVEKEKRY
                     FVKIKGNIKENMLVYGEFLKRYFFTKGFSLDDVIYSHTRKQLEDANFGWVFDCEGIDI
                     EEVENE"
     gene            complement(19600..19917)
                     /locus_tag="ACL72M_001396"
     CDS             complement(19600..19917)
                     /locus_tag="ACL72M_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716513.1"
                     /translation="MMEELKQKVNAVYNWTVEDGKPQPPKQDLPQVVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKDWLPKSREFDDWIGYSPSMAQVVIAVYLIY
                     GGN"
     gene            complement(19889..20098)
                     /locus_tag="ACL72M_001397"
     CDS             complement(19889..20098)
                     /locus_tag="ACL72M_001397"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716514.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKLEELEDDGRVKAKS"
     gene            complement(20085..20252)
                     /locus_tag="ACL72M_001398"
     CDS             complement(20085..20252)
                     /locus_tag="ACL72M_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716515.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGSPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            complement(20379..20606)
                     /locus_tag="ACL72M_001399"
     CDS             complement(20379..20606)
                     /locus_tag="ACL72M_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716516.1"
                     /translation="MLELYFVYNGHCKFYLGTFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            complement(20606..20800)
                     /locus_tag="ACL72M_001400"
     CDS             complement(20606..20800)
                     /locus_tag="ACL72M_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716517.1"
                     /translation="MFILKHGTREDKPFLMSAVIGVTGLDISCSEEKKAMRFVSRGAA
                     VQVGKALRGSFGNFYPVEVE"
     gene            complement(20815..21585)
                     /locus_tag="ACL72M_001401"
     CDS             complement(20815..21585)
                     /locus_tag="ACL72M_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0716518.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQARVNELADAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LVFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(21579..21737)
                     /locus_tag="ACL72M_001402"
     CDS             complement(21579..21737)
                     /locus_tag="ACL72M_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716519.1"
                     /translation="MGVLELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            complement(21725..22525)
                     /locus_tag="ACL72M_001403"
     CDS             complement(21725..22525)
                     /locus_tag="ACL72M_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGS0716520.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALEEDKDKNRLDKDK
                     NKKRITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENDVDLVKEALKTAINS
                     GKPNIKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            complement(22518..22814)
                     /locus_tag="ACL72M_001404"
     CDS             complement(22518..22814)
                     /locus_tag="ACL72M_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716521.1"
                     /translation="MEELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRDVELKNKLLKIEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            complement(22830..23150)
                     /locus_tag="ACL72M_001405"
     CDS             complement(22830..23150)
                     /locus_tag="ACL72M_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716522.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     AYMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPELLALPEPKQSG
                     IRFL"
     gene            complement(23236..23493)
                     /locus_tag="ACL72M_001406"
     CDS             complement(23236..23493)
                     /locus_tag="ACL72M_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGS0716523.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(23506..24219)
                     /locus_tag="ACL72M_001407"
     CDS             complement(23506..24219)
                     /locus_tag="ACL72M_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HGS0716524.1"
                     /translation="MNEIFNFHGQEVRTLTIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQVTMLEDIDYLKSEQPIHPSYAQSLLKKRKA
                     RVVACLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMELNSFDEG"
     gene            complement(24362..24565)
                     /locus_tag="ACL72M_001408"
     CDS             complement(24362..24565)
                     /locus_tag="ACL72M_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGS0716525.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVASSVISELLKYG
                     KGSESVKEKVADVLGIENPWRNH"
     gene            complement(24577..24723)
                     /locus_tag="ACL72M_001409"
     CDS             complement(24577..24723)
                     /locus_tag="ACL72M_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716526.1"
                     /translation="MEDKIIELADYFISENTTYREAKIACEKLFKQASHEIELRALES
                     ETKK"
     gene            24842..25063
                     /locus_tag="ACL72M_001410"
     CDS             24842..25063
                     /locus_tag="ACL72M_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716527.1"
                     /translation="MSKLTKEDVLQVSQEIINDAIPVIQDMLDEVFKEYPIDMEIRKA
                     ILNSVLVAHKLSTETTVSLLTELVNAQEN"
     gene            25441..25803
                     /locus_tag="ACL72M_001411"
     CDS             25441..25803
                     /locus_tag="ACL72M_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0716528.1"
                     /translation="MFFTFEKIKELADKQGISLNKLEEKLGFSRNTIYNMKKSTPNVE
                     RVSMIADYFNVSTDYLLGRTDNPTIAGSHDYKWEGKTLNVEEMASNVMMFGGRELTDE
                     KKKIIQSIIEGYLKEAGD"
     gene            25816..26199
                     /locus_tag="ACL72M_001412"
     CDS             25816..26199
                     /locus_tag="ACL72M_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGS0716529.1"
                     /translation="MTEKEIISHFQIRIIDFDGDLMPDELGFYEKETNTAFLSNKLSK
                     KERVKVLLHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDAIESLDDPTEFDYLK
                     FMSYYNLKTMTNEVMVKEEYFALME"
     gene            26212..27135
                     /locus_tag="ACL72M_001413"
     CDS             26212..27135
                     /locus_tag="ACL72M_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HGS0716530.1"
                     /translation="MSYSYVALDVETANDFRGSVCSIGLVKFKDGNIVDSFYTLINPE
                     EEFDDFNIFIHGITPEDVLDSPTFPEVRKAIVDFIGSDIVVAHFAQFDMGALKDVYQK
                     YELDFDNIEYICSYRLAKVALPGQLNYKLKRLAKNLNIELDHHNALSDARASGLILEY
                     LLSTNSFSDLNAFLKEYSYNKTGLLGQYGFKRKKSYQYKENLIYQPTEEEKAAMNPDH
                     YFYGLYFCFTGKLERMTRKEANKATALVGGIPEKGVTKHTNILVVGEQDWRVVGTDGL
                     SSKMKKAQTLLEKGQDIEIMTENDFIRLLEE"
     gene            27314..28462
                     /locus_tag="ACL72M_001414"
     CDS             27314..28462
                     /locus_tag="ACL72M_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0716531.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
BASE COUNT         8154 a         6741 c         4676 g         8933 t
ORIGIN      
        1 cttggcaatc tcagcttcag cctgtgcttg cttcggtcga atatcattcg cgatagtccg
       61 tttcagagcg tccaagtcac ccgacagagc cgtttgtgcg ctcgtagtct gcgacttaaa
      121 cgcttcaagt ctagcaacag aatccagccc aatccgcttg gattcctgag caagagaact
      181 acttgcgcca gcatttcgca aagcttcctc agccttgcgc ttagcttctt tcaatggccc
      241 gttgtcaaag ctattaaagc gctgattgat agtgtcagac agttcttgct tgacttcttc
      301 cgctttggcc ttggcaagtt cgatggcatc cgtgatggtt ttctcacgct tggaaaattc
      361 agcgtcaaag gcacggtcag cgttggcgat ttcctttttc aaacgttctt caaaaatctg
      421 atgcagattt cggctttcat tcaaaacggc atcatttaca atcccaccga tcgcatttgc
      481 aagactggac tggaaggttc caaaacctat tgattttagg agttttgcca ttggcgaata
      541 ggtatatttg gtgattttct tacgaacatc aagaccgtac cactcatggt agaagctgac
      601 cacatcaaac atctgcaccg caacatcact ctgaccgaca accgagattt caaggttatc
      661 ttctagcatg tcgcacatac ttgtccgaaa atactgctta ccgtattcaa tcaagctagc
      721 ctcatctgtc acgtcttggt cattgacttc caccacatct tcgtagattt ggctgtagtt
      781 cccaagtaag gggctgtcaa tcaccaccat ataatcatgg tcaaccgcat tttctccctc
      841 gcccttaaca gtcgttttaa aggttatccg agtttttaaa gacttcgttg aggtcttatg
      901 ctggtagctg gacaagtttt tcttgtacat aaaaagcgat tcattttcag aaccgccatt
      961 cttcaacaag cgtaaattgt agccgtttcg caccatatct ccgccccact gaccaaggat
     1021 agaatgcttg cctttggcca agacctccat ggcattctta tccttgatat tgagcgtatg
     1081 cctatcatca atatcagaga agaaagaaaa aggattggct ctggtaatac taccagcaaa
     1141 agcactcaac acccttgtcc cactgacacg gtcaacctcg atagagctaa cgatgtaatt
     1201 atttaacaaa ctgataacct gattggcata gacttgaata tatccttgtt gcttttcaac
     1261 ctcaaaaata taaaaatcct gctcaccatg caggtcatct gcagtcagaa aagtttcctc
     1321 tttcagtaat tcccacttgg tatccgatgt aggaaaacga aaggtcagtt gataggtatt
     1381 gttccccaaa tggacaattt catcattgta ggcctcattt aaaggtgtat tgccttcagt
     1441 aagataaatc ataagatata cctccaattc ggccgaaccg tgaccttgcg aaccgaacca
     1501 gtaaagacca gactgttatt accaactgcc aactcaaaga agcctccacg tttacgtaaa
     1561 gtattttgaa ccgcgccatc tgcattatag atattctgtt tcttatgcct acaatcaatg
     1621 gtcacttttc gtctaacggt caagtgcata gttgtccttc cgatagtcaa agaaatatca
     1681 ccgtctccct caatctcaat cacaggctcg ctatagacag agcctggatt gttgatattt
     1741 ccacttgcgg taaagataag aggagcaaca tttttctgat aacggaacgg ttgcatgttc
     1801 aacttgattt ctagtttcca ggcatgcatc ccatgagggc tataggttgc accaataaaa
     1861 tccgcataaa atacagaccc caactggtag ctaaactcta gcacattgtc cttaggctga
     1921 aatttctcca cgatagtaga aacatccagt aacttaggaa tatagaacga aaaagtccgt
     1981 tcataactct catagccacc atccagcact cgataacttc cgttggctcc gtagaggtta
     2041 gcatcttcaa ccaccctagg tttagctgcc tccacctgac caaaatccgt caccacgcag
     2101 tgagggatag ttgatgtatt aaacccattg ataatcatat aaaacattac attccctccc
     2161 tggcgtaaat tgcaccttga cgttggtaga cgctcattga aattttatca gcgtctaggt
     2221 aagtatctga cggcttttca aggatagcag taaggatttt ctccatactt gctctcagaa
     2281 tcgctatctc agacacgact ttatcgctgt ctttgctatt tgtctctcct ttggcttgaa
     2341 ccactatttt agcttgtgct tcttccatct cacgaaggaa tttagcatca ctcggaatgc
     2401 caactcctgc agcatattta ggaacaccca tctcacgcat caagcgtttg gtcttatccg
     2461 ctcgcaaaac tttagcccct ttaggaagag gaagaagaac atccctcccc tcaggaatga
     2521 agctcctacc atctggaaga gtaactaatt ccttgtaggt actattgcgt tggtcattga
     2581 ccatagcaag accacctgga tggtagttgg taccatgagc atgccgacta gcaaaaacat
     2641 tcgtaaagaa atcaccagtt accctaataa tccaagacct aatgcctgca agcacaccag
     2701 aagcattatc tcgagcgctg attgtaaccg ttttgtcttg aatactatta acgccacttt
     2761 tgacctcgct aacagtactg gaagtgctat ttttagcaag gatatctact ggattatttt
     2821 gcttaatcgc attaatagcc gcactcgtct catttctaac gcctgcagtc tgatctttcg
     2881 caagtaaatc aattggtttt tcttgtttcg gagagtttac gctggctttt gcactatcaa
     2941 ctgcttcact agtattgtca gtagcattta atgatttagt ctctggatta gatagattcc
     3001 aaaccatgat tttatctatt gacaattgcc cgttattcaa aacatttgta ggatctagtt
     3061 tcaaatcttt tgtaaacggt gtggttgcat tccaagtcgt tagcgtgtca gtcgaacgcg
     3121 caacagcctt tctgaaattc tcatccgtag ccagcaactc tttctgttta ggagtcaagg
     3181 catcgtagtt atagagagct ttggaagctt cctcagcctt attcatcaca tctgtatttt
     3241 ccaaaaggag ttgcttgact tctgcaggca tactgttcca gattctaaga tggttttcac
     3301 tatcaaagat agcttgcagt cctgcttgat tttggacaat caactgtttt tcttccagtg
     3361 tcatagttga ccacttacca gactcaacca aagcctcagc aatcatcaca cgagcgttag
     3421 agttgatatt cgcactttta acaataaatt gcaattgctc ccaaccctca gcagatttag
     3481 tcgcttcccc aattacttct tttacattgg atttaatctc aaagttgcca ttctcattaa
     3541 tattaccaac aagtaaagac caagcatcat tcgcttcttt tgtctctttg ctcatttcgc
     3601 tagtgtattt agcaagaata ctgtgagatt ctcccatttt ttgagaagct tctgctgcct
     3661 tttgaccgat tacttcataa gacaagccat attcttccag aaccttcttc gcttcttccc
     3721 agtagttcca gctttgccca gtccgagctt ttaccttagc gtcaaggttt tgcataacct
     3781 gataatattt agtccctaag gcttccatag tttgctggtg gtttgtttct aaagtttgaa
     3841 gtttcttgtt ataggtttct tggtcaataa cctttccttc cagcaactct ttcagctcac
     3901 ttttagaagt ctcataaagt tgtttttctt cgtccagaga cttcttcaaa acatctcgtg
     3961 tatgtttcaa ttgcgtctcg tttaaactac caatttctcc attcaaagcc tgaagcgcag
     4021 ccttctgttg ctctgctgac aagttcatca ttgaaattct agtttttatc atctctcttt
     4081 gattattcaa gatgatttct ttttcttctt gagaaaactt actagcatct ccattgtgac
     4141 gttggtaaat atcattgatt ttgttcatca tgctttcagc atttgaaacc atttgagcat
     4201 tcttctctct agcttttgcg aggtcttcct cactgagacc ccatttgcca gtcagttcct
     4261 gcattctctg gttagacttt tcggcaccag cagcaatctc atcataaagc tttttaaaag
     4321 ccccagagac tttctcagca tctccagcat gtgtaccaaa gttagcaact gctttgctgg
     4381 tttcatctac cttactttgg aagtctctta attctttcct tgcagtatca ctcaactgag
     4441 aaccaaattc ctcagcctta atacgcgcct cgtctttctt atgccctaga tagaccaatc
     4501 ctccagctag taaagcaaca ccacccacca gcaaaccaat cggatttgtc aaagccccaa
     4561 tagctccaga caagagacca gaactagatg cagcaacacc agctccttcc gctaaaacag
     4621 tggcttcact tcctacctta gcaagaccga taccaccttg taaaagtcct tttaatttac
     4681 cagcacgctc tgtcaattta gcaagaccga taccgccctt taaaagtcct cctaatttac
     4741 cagcatgttt tatcaaaata ctaagagccg tcgcaccatt gcctagaaag ttcaataaag
     4801 gatatcctag agccaaaaaa ccaccaatac caaccgccaa gctctgaacg gctggaggag
     4861 ccttacttaa ccagtcgata aattggttca ccttctcaat cacaggagtt agtaagggta
     4921 ataatttctg accaatgtta atctgtaaaa cttctaaact agatttaaaa cgttccacac
     4981 catttttaga agacttagat aattcatttg ctaaatcctt agtataagtt gtcgccccct
     5041 tggtttcgtt agcaagatta cgcaaagcat ctccaccttg gtcaaccaag atattcatcg
     5101 ctgtctgagc ttctgtacca aaggctgtag caatcaaggc cgatttctga gcatctgtca
     5161 ttccttccgt attctttttg atacgatcca aaatatcagg tagcttaatc gcaccactac
     5221 gaaattcttc tgcagaaaaa ccaagttttg ccattgcatt tgcattttgc ttagatggtt
     5281 tcagcagcct tgttaaagct ccacgaagag ccgtaccagc cttttcacca gcaataccat
     5341 tattggacaa aagaccaaca gtagctgcag tctcttccaa gtccatacca acgtttttag
     5401 caacgggacc aacatactcc attgcagccc ccatatcagc gaaaccagca gccgttttat
     5461 tggcgacaaa ggttaaacta ttggttactc gctctgtatc ctgagtagat agcccaaatt
     5521 gttgcaagat attcgtagtg gcgttcataa ccgtattgaa atcctcacca gacgccttag
     5581 cagcgtctag gatagcaggc atggcttcga ttgtttgatt ggcatcaaaa cctttcttga
     5641 taatttcttg catcccttca ttgatagatg cagtagaaat cccatactgt ttcgcccaat
     5701 tttttgaact ctcccccagc ttttgtgtgg tactgttcag ttcatccgct gttggaatag
     5761 tatcagctaa cagagattta gttgtattca tctgactttc aaagtcaatc gccttcttag
     5821 tcgaaagtgt aaaaccagct aataaagcag cagatacagg cttcattgca tcacccatag
     5881 cccgcaattt ttttccacct ttagcaaatt tctcactcaa ggcgtccatc ttaccagacc
     5941 aactattttc acgccctaca tcttgcaaag ctttttcaac accacgtagc tgaccttcca
     6001 ttgctgctaa cttggcattc tcgcgctgaa tatcagcagc agccttatca aacttagctg
     6061 tccccggttc aagcttgtca aaacttttct tcatctcatc caaaacttta cgttgtgaat
     6121 caatggcttg tcccaaagtc ttgtatttcg cttgaagtaa gctagcattt ttttcattcc
     6181 cttttaaagt actgtccaaa gaacggacag tattttgaaa gtactttaca gcgttttttg
     6241 caccagttag agtaggattg aaattcgaca cgtccagccc tagctcgata tacattgctc
     6301 ctaacggcgt accgcttgcc attttgttct ccttcctaac tcctcagagc aaagaaaaaa
     6361 gcccttacgg acttttcatc attctttata aaaatcatcc attgccaggc tcataaaagc
     6421 ccagataaac aaaccaagaa atagataagc gtagagcggc aaggaagcaa agataaaggg
     6481 tgataataaa agcataccca aggtatctcc aaaatttgta caaatacaat acaagccaaa
     6541 agcaagataa aggataaaga tggtaaacca aaaccaatat cttctacgcg ccttttcttt
     6601 tcgagacata tcttccacct cccttatata gctctattat attcctaagt cttttatttg
     6661 taaagtcctg acttagagac tctctaaaaa atctgccaag tcaaccactt cttcttgttc
     6721 actcgttttc atacttccaa gaacgcccat caagtcctcc caactcgtat ccatcacgtc
     6781 gcgaatactc attccataag gaccctctgt aacttgcttg ataaagccat aaaaacgttg
     6841 gatagcttgc ccaggtgcta gctcttttcc tttgggtcta catcacctac cagatgagca
     6901 taaatgtctg taaaaataga aatcactttt gcaaaatctg tgtattctag taattgttct
     6961 actgtcacat catcaaacaa actagcaata aatcccaact gcttatcaag cttctctacc
     7021 tcagataaat cacttgtcaa ggaatcgttc atgaccaaat agtcacgata atcacgagtt
     7081 gtgatttcct tactcttttt taggacatct tctcccttgt catttttgat tgtaaattga
     7141 accttagcca tatactttcc tttctaaaaa cggtaaaaaa gagagctttc gccctccttc
     7201 taccctgcag cagccatgtt tagttgaccc ttcaatttct tcaacttttc agcatccgaa
     7261 ccatagacaa tagcaccata acgaccctta gttgcggtgt ctgaactagc tgtcgcagca
     7321 aaattcacat tagtagtagc taactcatta gccttatcct tgattgtttc aaaatcaata
     7381 gcatccatag aaagctgacc tttataaaaa ccatagtaaa ccggttcccc atcagcagta
     7441 ttactttcaa tgagaatgga aacattctta gcaacagtgt ccgcaccgaa gtaatagata
     7501 ccatcatcat cgccataccc taaagcattc gtatataaag ctaatgggac atcaagcaag
     7561 cccatctcta ccttaacatc cccgactcct cgattggaga cgtgataagc aacattacta
     7621 ccataagtct ttacagggtc actagataat ccagttactc tagcggtctg tgtagcccct
     7681 tcattatctt taccttctag cgtaaagagg ttctgtccaa ccgttggagt ctgtccatca
     7741 tgcacacgaa tggtgactga tttaagtccg ataagtgcag ttccttttac tgtcatttct
     7801 ttttccttct ttctagtatt tctcatatag agcgctcata ccacgataag tccgaacgtc
     7861 tacatagcgc ttaatatcag gaatccattg ttccaaacca ccttcagtct gataaaatcc
     7921 ctgttcttcc attatttttt caattcttcc ttggagttct ttacactcca ctcgattagt
     7981 agactctaca ttgatttgat agagaaaagt cttagccaaa ctagtattac taccatgagc
     8041 cgtctgcatt ggaggcccta cagggataat gacaatactg gtctcgtcat ctcccaagct
     8101 ctcaggacgc tcaaaagact tgatactaat accagataaa gactcatcct cttccaaagc
     8161 atcgtagagt tcagttaatt tgtctttaat cattacaaaa actcctgttt taacttcatg
     8221 ccgactttag acttaaagac cggcttactc gcttcaaaaa agcggcgcat gactccgaaa
     8281 ccacgaggat gcccattctt tgcatagcca aattcattta agtgaataag agtccaacga
     8341 ggacttttaa aacctaattt aaccattgga actccgctgg atgtaccagt cacattccca
     8401 tgaacgaccg caccaaccgt cttcccagtg tcagcgtaca ccgccatagc ccgtttgaaa
     8461 gttggctcaa actcctcaac cgtctccttc aaggctctgt tgacatttct acgaactacc
     8521 ggctctccta gtcgagcctc aatattcctc aaaatatcat caaatccttt tagattagct
     8581 ccactagaca tcacgaccac ctccgataag gacaatcaaa aaatcccgat tatcataatc
     8641 aggacggaca tcaatgattt gccatttctt accaactaga cggatatccc ccacttcgac
     8701 aaaatgccga ttttcaggct gatagtctgt cagagggtca cgaatcttca aagtcatctt
     8761 agctttcatc gcttttccag tcgcaatctc aacgtctttc atacttggag aataagtttg
     8821 ccccatcgta taaaaagcct tctcgtaact cacatcacga ccatcaaccc ctttttttat
     8881 tttagaggta tagaaagtca ggggagttct caggtctcca ttttgagact caggcttttt
     8941 gtaacgatag cttggtccct cactcctctt catttacact cactacttcc ttagagctac
     9001 gacttctgga cgacttttcc aactcgacat agccaggtaa atgttccttt agctcagcaa
     9061 atcgttcttc tgtcgcttca aaccttcctc cgacctgcct aaggactccc tccttgaggt
     9121 cataaaactc ttttaatacc ttaatcatca ctatcctcca tttctatctt atctaacgat
     9181 aatgctaaaa tatccgcttt gaaattttcg taaaaaaatt caacttggtc attatagaca
     9241 tagcgagcac gttctaagat aagttccctt atttgatgat cgtgtatatt cccacttcct
     9301 accaagcggg taataaccat ttgagaactt tctaacatcc gtgagagatt cgcatcttct
     9361 ccgctatgaa aaattctcat ccgctcctta aaaggatcaa ggagggaatg aagtttagct
     9421 tcaatctcca tccttagtca ccttttattt tccaatattc agtgtccaca cagcagcagt
     9481 cttttcatca tgcgctttac cataagcaaa ttgcttagca gtgtagagat tcaagtcttc
     9541 taaagcatag gtttcggtaa atcgtccaaa ctcaatccca ccacctacaa aggcatcgta
     9601 gcgacctttg acaaacgtcg tcaccttacc agaagtttga gcaacagact caaccaagat
     9661 gaggttataa ggcatagctg ttacatatac accctgagca ttgagagacg tatattgctt
     9721 cttcacatcc caggcatcta cagggttcac taccataacc aaattacctt ctactgcaac
     9781 aggagtggta ttgtcagctt ttgtagaatg gtatttataa acctccgtca actcttttac
     9841 cacggtagca gagtctgcga aagtcaatgg ttttttctga gcttgtttct cagcataagt
     9901 tactttttca ctttctacag tccctgtaag agtacgagac agcccaatag gttgcttgtc
     9961 cccatcacca ttcaaataac cagcttcaag agcagcagca aaggcctctg taatttgaat
    10021 agagacataa gattgcaacc aagccggacc aaatttctca gagtctttag ggattacaac
    10081 aaaagcagtc aatttagact gaatcgcttc ttcttcagca aattcttgtt tcaattgtcc
    10141 ttgaatttca gcattgattt taccccaaac cgcttgacct gtacgactag acttgaggaa
    10201 tttcaaacga ataccagcat tacgcaagcc gatgtgttga agaagtggac gggctgccac
    10261 catatcctca aaaatacggt caattgtttc ctgagggaac aatttctcaa ttcctttggg
    10321 aggaagtttc tcaatgttgt tgaaaaattc gcgagcttca gcagtcaact gtgcatcgta
    10381 tggattcata gttgcgattt ctttacgagc agcttctcta gcatcatctt gcaacttatc
    10441 tgtcaatgcc tcaatcatct cgttatagag cttattttgc tcctccatag gagcaccagt
    10501 ttctactgca ttcataaagt tctgacgagc agttgtaaat tcattaccaa gtttcatcat
    10561 tgttttttat ttcctttctt aaaatgggaa acgacccaac cccacaggtt cagccgtctt
    10621 gtcttctttt ttcttatctt ctgggataag taaactgtta ttcaacctat cacgaaccaa
    10681 gtccgccaat aactccacat ctggggtcat cgcagatcgg attttttcga taaaatcacg
    10741 aggaatcaca ggtgtctgac tagctaccaa gacaggagct tcctgacttt caaacatgac
    10801 cttatctgcg aagccatgat taacagcaga acgagcatca aaccacgttt caccctccat
    10861 tagatccagt aaatcatcta atgccttacc agtcttatca atataggcat atgcgatgga
    10921 cttattaaac ccttctaaca caccagcctc atgcaagagc gccttatggt caccacgtac
    10981 accagcagat acattatgga tcatgatttg cgctgtagga ctaatttcca cctgatcacc
    11041 agccatagcg ataacactcg cagcactagc agcaatcccc acgattttca ccgtcacatg
    11101 cccctgataa gcacgcaatg ctgtatagat ttcactacca gcatacacat caccaccacc
    11161 agaattgatg tgcacctcca catcttctcc cgtcgtcggc aatacaatat ccttaggagc
    11221 agttgcatcc atgtctatcc aatcataaaa ccagcggtca tcattggata caatcgctcc
    11281 cttaatctga atgattgtca tcctcatttc ctcctttctc tatttcgttt tcaccctgat
    11341 agttcttagt gataaggaaa gaatccccac caggaacagc ctcaagacca agttccaatc
    11401 tcacctcatt tcgagtcata gccccagatg agatgagttt atctatgttc tcagccagag
    11461 caaacttatc cagtcccccc tcaccaaaaa tcacaaattt tttctgatta gcgtatccag
    11521 ccgaactcac catagcatgg tttagagcgt cacccacttt tttaaccagc gattcataac
    11581 aataactgtt aaacatcttc tggctattag acaaatcagc catatctcca tgcatcaaag
    11641 ccgtcggcaa acctaatata tccgcaacct cgtcatcaaa ttgacgtctc agtttcttca
    11701 actcttcaac tgatagattt gtagttccta ccgtattggt caactccgaa tactccacac
    11761 catccattgt cggtacaatg gcaaccgtct tagacgtaaa ggacttaaaa agattgtccg
    11821 catatctctg cagttttttt cgcttgtcat cgtcaaaggt tccattcgct tttgtagcca
    11881 gaaccccacg aatttgatta tttctagcta aggcttccac tagacgagta tgcagttttt
    11941 cataatcaga aaacaagtct gatacatatt cttgcaagcg attgttgtta tactggagaa
    12001 agatgacatc actcatagca aacttcctct gaaatatata atccccgaca gacaccatct
    12061 caaaggtgtc atcatacaga gcataacgcc tacgagtaaa agcatcagct accagtaact
    12121 gcttatcatc agacaagaca ataagtactt cgtttttcgt caataagcga taaatgacct
    12181 tctgccaaaa ctctgaggcc gactcattct tattgggacg cacatttaaa atataatccc
    12241 agtctgacgc cacatgatga ttctccacca tataccgaaa ttccgactta gcaaagatac
    12301 gagccacaaa ctccgccgac ttatcaatcg ctaaactctt caattgcaag cgtcccaaca
    12361 ttcgttccaa ctcttcaaag tcaaaaccaa catcaggcgc atcacgctta aataagttta
    12421 agaatcccat gcttcccctc cttcctctta tttttgccga ccacccaccc aaaatttatt
    12481 cttagattaa aagtcccagc tatcgagcat gtcaaggaat tccccaacgt ttgactcatg
    12541 tactagctcc ctcttgtata gagcagcaat caaggcatgg aaaccatctg tctttcttct
    12601 gaccggctct ttcttcaaga aacgcttatt gccatcctta tcctctttga tataggtatt
    12661 atccgtatac caaatcatag agttatcgtt ctcaaagaca aaccgctcat tggcaaatcc
    12721 gtcttcaatg attggcgcaa ccttagattg aatcgcccca ggattccgca agaactcata
    12781 ttcaaaacca gcctcttcca aaagcggttt taacaagtcc attctgaaac catcagcaca
    12841 tacaagttca atctgataaa acttactcca ttcttccagc ttcgcaacca acagccgcgg
    12901 atcaatgcta ggaccgtcca caatcgtaaa caaaccttta tctgcccatt cctgaatagg
    12961 ggcttttagt ttgaaagctt tcaaaaacac tttacgagca aatgaatgtt gtttccagat
    13021 aaactcatcc ccgttcttaa acaacaaacc aacacttgca aagtctcgaa tactagcata
    13081 gtcaaaccct gcaacacaag acttacctaa caagtcaata ccaggtgaac gcaaacaagc
    13141 aactaacttt tcacgagagg tgacatcttt ctcaaggtca gcttcaggaa ggttcatccg
    13201 tttagtcata aactcctgac gaccagatgg ttccaactca aggtcatcat agtcagcttt
    13261 agttcttgca agtaacctct tagcgtaagg agtgctttca tccaacatcg gatttgcctt
    13321 tggccacttc ttcatatcat ccacttcatc cgcactgtct aacttacaga tgaaaggaaa
    13381 gagcctgaaa tcatcaacct ctccgttcaa gatttgcata gacttctcta tcagcttgtc
    13441 ataaaatccc tcacgcacat acccattcgt accgttgtag aaagtccgag catgagcaat
    13501 cttaccgaga cctgaccgtt gaaccttcac ggccttatca tcttcaaact ggtgaatctc
    13561 atcaaactca agacagccat cacgagcgga gtccatggtc ttcggattat tcgtccgaaa
    13621 agaaaagacc gagttgttcg ctcgacctgt aatagacatt ttagttagat agaaatggtc
    13681 ctcaaggcca cgcctttgaa tagtctcata gacctcctca aatgaaacct tgccctgttt
    13741 ctcagaattg gcagtgatag tcacatcata atctctgata gggtagatag gactgataaa
    13801 gaacgaggat ctggcagaca taaaaccatt cttaccaccc ccacgagcaa gtgtgtacaa
    13861 atactcgtcg aagtgtggct ccccgtcttc cttccgaaaa agaaagataa acggagtcaa
    13921 gaaaagctga tacttggcca gagggaaaaa attcttttcc gcaaaacgaa tgaacttatc
    13981 aatcaagtca ttatcaaaat acaaatcatc acgaggatag attttctcct tgatgatttt
    14041 aaacagcaac ttcctttcct tgttgacgac aatttctcca ctctcggcca ttttgatgta
    14101 gtcatcaacc aagggatgag aaatcatagc aggtcacttc cagacgtggg tttctcaaca
    14161 ggagaatttt caacctcaaa atcaaacgat cgctcaatag ccaaaagctg attgcttgtt
    14221 gtgttgattt ccttgatgag agaattcgct ttttggaatc tctgttgccc attgtgaaca
    14281 gtgatgacca atccgtcttc atgaagttta gctttcagct catatagcaa tctgacaaga
    14341 taaagataac gattcacttt ttcgtactgg atcgcatcct tttttctcgg actgaaatag
    14401 ccgattttgg aaagtagctg attttctaat tcttttatat ttttttccga gtattcttcc
    14461 attacccccc acccccttta attttttgtt aaaaatttgg acagtcgagt gcagaccgct
    14521 tactggctcc tttgaaattt cctgattttt ttgaccgggg ggtgtttaag attcgttcac
    14581 ctaaccccac cattcatctt ttcggaaatt tctgtcattc ttatcaaaac gatcatgcct
    14641 tttattatga catgctttgc acaatgttcg taggttatcg atatcaagcg cgaactctgg
    14701 atataactct agctccttga tatggtcaac ttctaaatta gtagtcgtga ccttgccttc
    14761 atccctacac catacacatt cgtaatgatc tcgtttaagt gcttgccttc ttatcgttct
    14821 ccactcgctg gaattgtaaa actggttgcg ctcttctcga gttgaaacat caatcatttg
    14881 attattgatg ttgatacttt gagctcaaat ttatttagct tgtcaataca attgttcaag
    14941 tgttcgattg cttcacaaca ttgttgagtt aactctttta attctgagcg attttcaatt
    15001 tcgactccaa ctacaatttt tcctaatggt ttttgtttag tggttctttt attaaaaagt
    15061 cttttaataa tacctttcat aactgtgcaa tctcctttgt ttttactctt tcaattcctt
    15121 gttttacata ttctagtgaa ctcgctacat gagttttaac tcagctttat caagcgttta
    15181 tcttgcatgt gcgaaatgaa atcatcataa ccttaaaaca atgaattgat gttaaaataa
    15241 aaaaattaaa agccctgaaa tttcgtcatg gctctgtctt gtgaatcttg atttttgccg
    15301 atataccgaa gtgaaatact ctggcttgag tgattcagta ggtccattat cagagcgaca
    15361 tccttggttt gttcgtacat gaataaacca aaggtctttc tcatagagtg agtagctatg
    15421 ttttccagac caacttcttc agcagctctt ttgataatct tataagctgt gttaggtttt
    15481 atatgctgat gctttccgtt tcggcttgga aagaggaagt cttcatcttt cttatctttt
    15541 atgtactgcc tcatagcatt cttgaatttc tttggcatct ttcgtttggt tggcttgtct
    15601 gtcttttcat cgacgatctg gacatgccaa cctttaacgt gctttacttt cagtttaacg
    15661 atatcaccaa tacgaaatcc caaattaaca ccagaaagga agagcatgag gttgcgttgt
    15721 ctatctgact ctttgactgc actatgcaac gtcagccatt caatcataag ctgaacatca
    15781 tctctatttc ggattggttc aacaactacc acatatcctc acctcctttt aatgcaaaaa
    15841 aaagcagagg tttcctccct gctattcttc atgatactaa tttaccacat taaaattatc
    15901 atttgctatc attcttatca tacattttag ataattttag taacgcttta tgttttgctc
    15961 gttggatagt ggcagggcta caatttagtt ttatttgaac ttctttccaa gataatccgt
    16021 caatgtacaa taatcgcatc acgatgtttt ccactggatc atcgagcgac tcaatcgctt
    16081 gaacgagttc gtcacgttcg tggtacattt gtttgatttc tttatatagc tgttctgact
    16141 tgtcaataat caacacattc aattcttcag tttgattctt gttacttttt gattttggca
    16201 tgctgtcgaa ctgctgtcct cgtaaaatac ctgacttcaa actgatgatt tcttggtgct
    16261 ttgacttagc tttgatatcg atataaggca aagccttcaa tctttttttg atgtctattg
    16321 ccaaatctta cctcctgacc gggttttcgt agatgttgcc gatgatttcc tcatattccg
    16381 tccacgcata tccatctcca aatcctttta ggtatacagc aggcattcca cctatgaatg
    16441 taccaccata ttctttttct aaatatactt catggagaca tcctcttgta catttaacga
    16501 tgtcaccgat gaatacctcc ttgccgttct tgtctctgag tcctgttgat tgtcctaatg
    16561 ttgctggatt tacaggacac caagaaccta tagtaatgta ttgttcattg gcttctacca
    16621 cttcgttgat aataaatgct cttcctctat cttcaattaa atgtccgtat tgccattctc
    16681 ctttgctttt ttcgtcaatg gataaccctc taaattttgg tatcatgcta acactcctta
    16741 aataaacaaa ctagctaacc atatcaaaaa tgcacatgta atgatttttg aaatactgct
    16801 ctttaccgca tacgaataat cctcttcaga ttcttttttg ctagataaca caggccagat
    16861 gaaagatagt agtgcatcca tccctaatgc ttgccagact gtaattttac caactggaac
    16921 aattgttgtg ataatctcat tccatccata ctgaactaca aatggcgata caacgattac
    16981 aaataccgcc ccaataatga ttcctagtct tttcatttta taaatcctcc tctttgacga
    17041 aagcaccatc aatccaacga ccctaccgtt ttctaaatca cggtcaataa accattgttt
    17101 gactttctct attgtgttca tgataactcc tttgctattg ctgctatgac attaactgtc
    17161 acgctatttc ctgcttgttt atataattga ctgttagagt tgacctcctg cgccttatca
    17221 aaagcccaat caggaaaacc ttgtaacctc cagcattctc taggtgttag ctttctgatt
    17281 cgaaagccat ctgataaatg attgttttcg tgatagctat tgctagttaa agtaggagcg
    17341 atgtcatgtt ctccaccttt attataacca tgcccacgtt gaataatttt aggctcaagt
    17401 cctccacctt gataggctct gatagttggt gcgatgccgt ctgtttcgta aaccacccca
    17461 cattgattaa aattgggttg caatacccca aattgtttta tagtattgct ttttatagct
    17521 atcttttgcc cctctccctt gtttgttgtt agcgtgggag ctagaccatc agcttgatag
    17581 acttccccat tcattccgtt gccagatggg tttatattcc caattttcat gactgattgg
    17641 ttactagttg actgattttt tccgctgaga ggaaaaaatc ttctggtacg ttctcttcta
    17701 agatgtccga taatgaacac tcgttcccga ttttggggga ctccgaaatt cttgctgtta
    17761 agcacttgcc attccacgtt gtaccccagt tcatccaagg ttgagataat ggtctcgaat
    17821 gtaactccat tttcgtgatt gagcaatcct ttaacattct caaggaatag atatttaggt
    17881 ctgagaatag atgcgaacct agcaatttca aagaacaaag ttcctcgtgt atcttcaaaa
    17941 cctcgtctgt ttcctgcaat tgagaaagct tggcacggaa atcctccaca gataatgtcc
    18001 acacttccga ttcctcgaat agattcatct gatactgctg tgatgtcatg taattctatt
    18061 tctcctttcg tattgtgtat cgctttatag ctttctctag caaacttgtc aatttcacaa
    18121 aagccaatac atttatggcc ggcagactcc attcctaaac gaaaaccgcc aattcctgcg
    18181 aataaatcca agaatttcac aacatcacct catccccaac tttcactttc tcatacacgt
    18241 tcttcaaaat aactatgaaa tttacttaaa ttgacaatag cgacctcttc aacagaatgc
    18301 tttccgatgt caaagtctgg atcattcttc ccaaactctt tttctatagc tttttcagcc
    18361 agaaaaggca aatcgaatat acttgcccca tttcttaaag cgagcgcttg accgtatttg
    18421 ttcactattc gataccctat atcaaacggt ctgatttccc ttgggacttt tatgcattta
    18481 cttttattct tcattccttc ttcaagtgtt tgtgtcatca ctccacctcc tcaatctcaa
    18541 tacctgggca atcaaacacc cagccgaccc ctacttcttc tagttgtttg cgagtaaatt
    18601 ttgtagctag tccacccata gagaagaata gtttcttatc catagcatta taatatagcg
    18661 gttgttttgt tgctttcgtc actactgtat accgcttctc ttcctcgacc tcgtagccga
    18721 actggtgcat gttgacgagg gtttgaatag gattttctct gctattatta atccaattat
    18781 taaactctct attttctgat tttttagcct catccctgaa agcaatccaa tcccaaacat
    18841 taaattcaaa agaatcctta ttctcttcat accaatccgc cacaaactgc ggtactacga
    18901 ctttaatttt ggatttatca acgatgtcgt ctgtaatata aatattattg ttgggtacat
    18961 tgagagtttg cccgtattcc aatctaacaa cattttcaac gcacttgttc tcatccacat
    19021 caaaaccgac tattttccct ttcaagagaa cttcatcccc tataaaaaag ttaaagcgtg
    19081 gtgtttcaat tagatcttta ttcattttcc acctcctcta tatcaattcc ttcacaatca
    19141 aacacccagc cgaagtttgc gtcttctagt tgtttacggg tgtgggaata tataacatcg
    19201 tctaaactaa agccttttgt aaagaaatac cttttcaaaa attctccata aaccaacata
    19261 ttttctttaa tattcccttt aatcttaaca aaataccgct tctctttttc gacctcgtag
    19321 ccgttaagcc aagctagtgc gaagagttcg gaattatccc aataccattc tgcaactatg
    19381 tcagacatgc ttgcgtctat tgagtaggac agtgtatgac ccagtttttt ctgttctgcg
    19441 ataaaatccg ccacaaactg cggtactttg actggttgcg gttcgcctag ttgttcaaag
    19501 atttctttta catccttcca ccaaactaca taaccttgaa aattcctagt cattgttctt
    19561 cgttcctcta attttttaat caattcctgc ttattcatct tagtttcctc cataaatcaa
    19621 ataaactgca ataactacct gagccatgct tggcgaatag ccaatccaat catcaaactc
    19681 cctagatttt ggcaaccaat ccttagtagc tcccaaatca tagtctgtag gcttttcatc
    19741 agcaaagatg cattccatcg ctcccataaa cgtcatacca tcttctgcca tttcccaaaa
    19801 atagtccgcc cggtctttca ccacttgtgg taaatcttgc ttgggaggtt gcggcttccc
    19861 gtcttctacc gtccagttgt atactgcatt aactttttgc tttaactctt ccatcatctt
    19921 ccaactcctc caatttccgt ctcaattctt tattcttttt cctcaacaaa tcgcgctcca
    19981 gcgctctaat ccgtctcttg cgtgcatcgc acggcttcga atactcgatt atcttctctt
    20041 cgttttgctc gatcgtgcgt ttcagtccgt caatctcagc ctgtttatcg tacttcatct
    20101 tctaaaaatc tttcaatagc ttctctgtag gagacttcca ccagaccgtc taagtcgttc
    20161 agggcttcaa tatagtctgg actaccttgc ccgtactgct ctttcaaaaa ttcaacaaag
    20221 agatgaattt cctgataggt tactccaacc atgtttctta cctcccacta aaaatgtaac
    20281 gttattgatc atctttcttt tcctttcttg ctacacgttc ctcgactaaa tagccgagaa
    20341 ataaccacag aatagccatt ccaaattctt taataagttc aatcattttt ttctcctcct
    20401 gaaaaagtcg ctaaatagta acaatcctta gagccgtagt caaatcgtgt cgtccgctga
    20461 ccaatgtgct tctgaaatct tggatgagtg atagccgaga aagcccactg atgatcttcc
    20521 atctgttcaa tgagatcatc gacattgtca aacgttccaa ggtaaaactt gcagtgcccg
    20581 ttgtagacga agtaaagctc taacatcact ccacctcaac gggataaaaa ttcccaaagg
    20641 aacccctcaa tgccttacca acctgtacgg ctgccccacg agaaacaaac cgcatggctt
    20701 tcttctcctc agaacatgaa atgtccaagc cagtcacacc gataacagcg gacatcagaa
    20761 acggcttatc ctctcttgtc ccatgcttta aaataaacat cagccacctc cattctaaaa
    20821 atattgtttc cgcttgttcg tcaaatcatt gaaaaccatc aaatggtctt tatccacccc
    20881 cttcatcagt ctggacataa agggtctgcc atatcttttc tgaatatcag cagaaatcaa
    20941 attcgtggta atgattgtat ttgaacgctt attcaggata ttgtagagaa tagtaaacga
    21001 ccattcgcta tccttctcca tgcccaaatc atccaaaacc aagaacttag cgctagcaat
    21061 cttattgacc agaaactctt cctgactaaa atcagcttta atcttcatca gcaagtccgt
    21121 cacattgata aatatagcaa tctctttcgt gtactcagat aaagccttta ccatagcaaa
    21181 ggccaaatgg ctcttgccag ttccagcttc tccttgtagc acgatgttgt tcctagcacc
    21241 ctcagaccac tcacgacaaa tcctctttgc aaaaactagc ttttccgctt ctttttcggt
    21301 tggcgtctca aaattgtcca aagtcgcatt tttcaaaacc tcatcataaa gagagaactt
    21361 ttcaagatag tatttcctct ctcgctcatt ctcagcgtcg gccagttcat tcactcttgc
    21421 ttgattctcc tcatggatcc gctcagattc acacatgcga catacaacac tttcagtccg
    21481 caatatcttt atcaaaggga tgttatgctt ttcacagaac tcttcttgtt gttctgtatt
    21541 cctacgataa gataaggcga tttcctcaaa cacattgtct accatactag tcgacctccg
    21601 cattcatgcc agctagccat ttcagacaag caggcaacca cttgatgaat tggttggtct
    21661 gctaaaagag ttttcttctc gtagcttaac ggataatagt caatctcgaa ttgttcaatt
    21721 agttctagta cccccattcg tccttggcct cctgttcttc tttcttatcc ttgttcttct
    21781 tttccgattg acgaacctgt tcaacagtgg taacattgtt catctgccaa tttcttaaaa
    21841 tcccaccaat atatttgatg ttcggctttc ctgagttaat agcagtcttc aatgcttctt
    21901 tcaccaaatc cacatcattc tcatttagta gatggttgat ttcttcaatt tcaaatccag
    21961 ataagagtct acgaaactca gattgaaaaa gttctaagat attttcttca ctaccactac
    22021 tagtagtagt tattcttttc ttattcttat ctttatctaa tctattctta tctttatctt
    22081 cttctagtgc gttaccgtcc gttactgtaa cgttacctgt aacgttacca agagcaagat
    22141 ttttttgttt tttacggtat ttggctacac ggttacgtgt ctgttccttg attttctcca
    22201 ttccgtcaac gttttgatgt ttttcccaat ttggcaagct aataatacca tcgataatct
    22261 caatcatccc aaactgttca aaaactccaa tagccattct tactgtattc aatggtctac
    22321 gaaaaatagt agctaacatt tcatctgtat agtgaacctt atcagtcatc atcaacaaac
    22381 cattactgtt atgttttcca gcaagtgtca aaatcttgaa ccatatcact aagatggcat
    22441 caggatcagg caaggcatca atcaggcaaa tcttttcatc gtcaaaaata tcggttgtga
    22501 tttttatcca cttaatttca gacataccga gcaccccact tcctgcgatt ggcacgatac
    22561 ttcatacgca tatcctcata gatgtgcctg ccttccagct ccattttttc aatctttagc
    22621 agcttatttt taagctccac atcacgatag tccttagcta gtttttcata gtctgttagg
    22681 tattctttga ctcgtaatag atttttataa tcgttttccc atatcgtaat aaaatgtctt
    22741 gaagttgatt cccttccttc cagttcttta acaatcataa tcaggttatc cagcgattca
    22801 atcaattctt ccatttcctg acctcctcat tacaaaaatc tgattccaga ctgtttaggt
    22861 tctggcaaag ctaacagctc agggcgcaat cctacaggcg gttcgttgtc atatgtgaat
    22921 cctttgaact ctctgcgaat attcttgcga atttcttgcc atttgtcctc tctaccacgt
    22981 tcatatgcat gattacgcac ttggataatc atatacgcaa attcttgctc ttctcgtctt
    23041 tcttcttcct tgcgttgttc ctgcaatttg atatgacggc aagcccctgc aaatccaagc
    23101 agcaaggctc caacccccat cagctggtct aaaatcggtg gttcaaacat ttttatctcc
    23161 ttatcctctt tttgtgctat aatatagtca aataattttg ctaagacctt gtccagaagc
    23221 cttttagtaa agttattata tttgattaga gagccattct ttgatggctc tttttgacca
    23281 tttcttacca ggtaattcct ttggaaatcc ctttaagtaa cgataattat ctgaaaatgt
    23341 ggcatactta attcctagaa aatcacaggt agtgttcaca tccatcagct ctggatagtg
    23401 gtcactatct ttttctattt cgactagcct tgtgattgtg tccttgataa tggatttaat
    23461 ccattcagac agtgaaagta gaacattgtc catcttcttc ccctcctacc cttcgtcaaa
    23521 tgagttcaat tccatgattt tcatcttggt attggtgctt ggctcccaag tcatccaata
    23581 ggccaaggct gcatctgcga attttttcgg tagcaagtca tagcgattaa tgttgaagtg
    23641 gtctttaaag tcaatctcag cttgtctaaa gactgactga gcgaaagtct tatccgcata
    23701 agccggacta tcaatgccac ctaagcaagc cacgacccga gccttacgct tcttcagtaa
    23761 tgattgagca tagctaggat gaatcggttg ctcactcttg aggtagtcaa tatcttcaag
    23821 catggtaacc tgttgctcac gcaatttctt ttgaccagtg aatagagcga taaaggcatc
    23881 ctcgtccaag tcctcgcgaa tgaaaccgcc ctgcttgcga atagctggca aaacctctga
    23941 tgtcacccag cgcttaaact ctttagcctg aggcaacttg ctggataaga taagagagta
    24001 gagaccagat tcgttgatga taatagtttc ttggaccctt cctaaattat ctgtgaggcc
    24061 ctgttttagg gcgtcatctt catcaacatg aagagcaatc gcatttctag ccttgctata
    24121 tcctaggatg tctgcaacat ctttcccaac gaaccaaggc tcgtcatcaa ttgtcaaagt
    24181 acggacttcc tgcccgtgaa aattaaaaat ttcgttcata atattcctct tcttactttt
    24241 cctagtgtta aaatagtttc ccaaacatct agtccctcaa gactatcgat catcatctga
    24301 ctaagttggt gatttttctt ctgccaattc agtattattt tcgcttgcat gtatggacct
    24361 ctcagtgatt tctccaaggg ttttcaatac ccaaaacatc tgcaactttt tccttaacag
    24421 actcactacc tttgccatac ttcagcaact ctgaaataac tgatgatgct acagatactt
    24481 gttttgccaa ttcagcttga gtcatatcca actcaatcaa acgagttttg attttagcct
    24541 tgattatctt tagttcttta ctcatctttc tcctttctat ttcttcgttt cactttccag
    24601 cgctctgagt tctatctcat ggctggcttg tttaaatagc ttctcacacg ctattttagc
    24661 ttctctgtac gttgtgttct cgctgatgaa gtaatcagca agttcgatga ttttatcttc
    24721 cattcaacct cctatatcag tctcaagact gaggtaatat cttcctaaat tgctataata
    24781 atcttgacta ggacctctca ccgttttagt caaaattcca atagaaagga ggaaatttta
    24841 tatgtcaaaa ctcactaaag aagatgtttt acaagtttct caagaaatta tcaacgatgc
    24901 tattccagtt atccaagata tgttagatga ggtatttaaa gaatacccaa tcgacatgga
    24961 aattagaaag gctattctta atagcgtcct tgtcgctcat aaactcagta cagaaactac
    25021 ggtttcgttg ctaacagaac ttgtaaacgc tcaagaaaac tagtgtttct tagaattttt
    25081 tctactaatt cagggtctgc ctttacgagg gtagactctt ttttcccact atacggatat
    25141 cgtcttggtc tcatttcctc acctcctttt aaaaaattat ctaaaaagtt agcgaatttc
    25201 ttgacattga taaataaatt tattaaaatc aaaacataga gaaaagacct actaaaaagt
    25261 aaggttatac ctagaaaacg gacgccaatc agtttcatta ggctttattt tttagttgtc
    25321 ttgttcgcta actctttagc ttacaaaaac tattgtagta aatttattaa actttgtcaa
    25381 cagttttgta gtaaatttat taaatatttt ttgtcatgcc ttagaaaggt tgatgtatca
    25441 atgtttttca catttgaaaa aataaaagaa ttggctgaca aacaaggtat ttcattaaat
    25501 aaacttgaag aaaaactagg ttttagcaga aatacaattt ataacatgaa gaaatccaca
    25561 ccaaatgttg aacgagtttc aatgattgct gactacttca acgtgtccac agattattta
    25621 cttggtcgca cggataaccc aacaatcgct ggtagtcatg actacaaatg ggaaggtaag
    25681 actctaaacg ttgaagaaat ggcatctaat gtcatgatgt ttggcggtcg agaattaaca
    25741 gatgaaaaga agaaaatcat ccagtctatc attgaaggtt atctcaaaga agctggtgat
    25801 tagaggtact gcttagtgac tgaaaaagaa attataagtc attttcagat tcgtattatc
    25861 gattttgatg gagatttgat gcctgatgaa cttggatttt acgaaaaaga aaccaataca
    25921 gctttcttgt ctaacaaact cagcaagaaa gagagagtta aagtactact gcatgaactt
    25981 ggacacaaag accacacacg ctcagagtac cagaacgctc gcctacgctg tgaaaacgaa
    26041 gctgatagga atatgatcca tcatctcgta aaagacgcga tagaaagctt agacgacccc
    26101 acagagtttg attacctcaa attcatgtcc tactacaatc taaaaaccat gacgaatgaa
    26161 gtcatggtaa aagaggaata ctttgcattg atggagtgaa aggagactca tatgtcttac
    26221 tcgtatgttg ctttagatgt tgaaactgcg aatgactttc gcggtagtgt ttgttctatc
    26281 ggattagtaa aatttaaaga tggaaatatt gttgattctt tttacacttt aatcaatcca
    26341 gaagaagagt ttgatgattt caatattttc atccatggca ttacacctga agatgttctt
    26401 gattcaccta cattcccaga ggtgagaaag gcgattgttg attttattgg ttctgatata
    26461 gttgtagccc actttgcaca gtttgatatg ggtgctctta aagatgtata ccaaaaatac
    26521 gagctggatt ttgataatat agaatatatt tgttcgtatc gattagccaa ggtcgctctc
    26581 cctggacaat tgaattacaa actaaaaaga ctagctaaaa atttgaatat tgagctagac
    26641 caccacaacg ctttatcaga tgcacgagca agcggattga ttttagaata cttattatct
    26701 actaattcat tttccgacct caacgctttt ttaaaagaat atagctacaa taaaactggc
    26761 ttacttggtc agtatggatt taaaaggaaa aaaagttatc agtacaaaga aaatcttatc
    26821 tatcagccaa cagaagaaga aaaggcagca atgaacccag accattactt ttacggtttg
    26881 tacttttgct ttactggaaa actcgagcga atgactagaa aagaagctaa caaagctact
    26941 gcattagttg gtggtattcc tgaaaaagga gtgactaaac acactaatat cttagttgta
    27001 ggagaacaag attggagagt agtcggtaca gatgggttaa gtagtaaaat gaaaaaagca
    27061 caaaccttgt tagaaaaagg tcaagatatt gaaatcatga cagaaaatga ttttataaga
    27121 ttgcttgagg agtaattaac aaaaaagctc cacaatctcc ctcgccaaag tttgattgtg
    27181 aagcccaccc ttataaaaaa tcagccatta aaaaggcctc ttttctatac tctattttac
    27241 accatgaaag gggtgatgtc aatattctca atgtttagac cttgtccaga agctgataaa
    27301 caaggagaat acaatgaaat ataataaaac aaaataccca aatatctatt actatgagac
    27361 tgctaaaggc aagcgttact atgtcagacg ttcttttttc ttccgaggta aaaaaagaga
    27421 aaaaagtaaa agtggtttca caactctccc tcaagctcgc gcagccttgg tagagcttga
    27481 gcaacaaatt caagaacaag aattaggtat caatacgaat ctaacgcttg atcagtattg
    27541 ggatatctat tctgaaaaga gattgtcaac agggcgctgg aatgacactt cctactacct
    27601 caatgacaat ctctataaga accatatcaa ggcaaagttt ggttctatcc tgcttaaaaa
    27661 tttggataga aatgagtatg aactatttat cgctgaaaag ttgcagaacc ataccagata
    27721 cactgttcaa accctcaatt ccagcttcat ggcattgctg aatgatgccg tcaaaaatgg
    27781 aaatctgctc tcaaatcgct tgaaaggtgt tttcatcggc cagagtgata tccctgctgc
    27841 aaacaagaaa gtgactctca aagagtttaa gacttggata gcaaaggcag aagagattat
    27901 gccaaaacaa ttctacgctc tgacctatct gacaattttt ggattgagaa gaggagaagt
    27961 ctttggattg cgtccaatgg acatcactca gaacgacagc ggacgggcta tactgcatct
    28021 tagagacagt cgaagcaacc agaccttaaa agggaaagga gggcttaaaa cgaaggattc
    28081 agagcgatat gtctgccttg atgatatcgg aacagacctg atctattatc tgatagctga
    28141 agcttctaag attaagcgaa agttaggaat tatcaaggaa cagcacaagg attatataac
    28201 tatcaacgag aaaggtggtc tcatcaatcc aaaccagcta aatagaaact tcaatctagt
    28261 gaatgaagca acaggattgc atgtaacacc tcacatgatg cgccacttct tcacgactca
    28321 aagcattatt gcaggggttc cgcttgaaca attaagccag gcgctgggcc atacaaaagt
    28381 ctatatgacc gatcgttaca atcaagtaga ggacgaactt gctgaagcga caacagacct
    28441 atttcttagt catattcgct aaaaaagtcc ccgccaattc cccgaccaaa atccgaaaaa
    28501 tacc
//
LOCUS       DBERCW010000026        28235 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.026, whole genome shotgun sequence.
ACCESSION   DBERCW010000026 DBERCW010000000
VERSION     DBERCW010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 28235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28235
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.026"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            548..928
                     /gene="dhaM"
                     /locus_tag="ACL72M_001415"
                     /pseudo
     CDS             548..928
                     /gene="dhaM"
                     /locus_tag="ACL72M_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
     gene            1386..2099
                     /locus_tag="ACL72M_001416"
     CDS             1386..2099
                     /locus_tag="ACL72M_001416"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGS0716532.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2157..2561
                     /locus_tag="ACL72M_001417"
     CDS             2157..2561
                     /locus_tag="ACL72M_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716533.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQ"
     gene            2897..3550
                     /locus_tag="ACL72M_001418"
     CDS             2897..3550
                     /locus_tag="ACL72M_001418"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGS0716534.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3560..4024
                     /locus_tag="ACL72M_001419"
     CDS             3560..4024
                     /locus_tag="ACL72M_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGS0716535.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4037..5305
                     /locus_tag="ACL72M_001420"
     CDS             4037..5305
                     /locus_tag="ACL72M_001420"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGS0716536.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKFNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5319..5579
                     /locus_tag="ACL72M_001421"
     CDS             5319..5579
                     /locus_tag="ACL72M_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716537.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5590..6951
                     /gene="pdrM"
                     /locus_tag="ACL72M_001422"
     CDS             5590..6951
                     /gene="pdrM"
                     /locus_tag="ACL72M_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGS0716538.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7105..8073
                     /locus_tag="ACL72M_001423"
     CDS             7105..8073
                     /locus_tag="ACL72M_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGS0716539.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8089..9081
                     /locus_tag="ACL72M_001424"
     CDS             8089..9081
                     /locus_tag="ACL72M_001424"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGS0716540.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNSVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9299..10342
                     /locus_tag="ACL72M_001425"
     CDS             9299..10342
                     /locus_tag="ACL72M_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGS0716541.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10388..12091
                     /gene="lpdA"
                     /locus_tag="ACL72M_001426"
     CDS             10388..12091
                     /gene="lpdA"
                     /locus_tag="ACL72M_001426"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGS0716542.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTS
                     NDDDKSDDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12155..13144
                     /locus_tag="ACL72M_001427"
     CDS             12155..13144
                     /locus_tag="ACL72M_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGS0716543.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13217..14287)
                     /gene="xerS"
                     /locus_tag="ACL72M_001428"
     CDS             complement(13217..14287)
                     /gene="xerS"
                     /locus_tag="ACL72M_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGS0716544.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14871..16421)
                     /locus_tag="ACL72M_001429"
     CDS             complement(14871..16421)
                     /locus_tag="ACL72M_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGS0716545.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16437..17216)
                     /locus_tag="ACL72M_001430"
     CDS             complement(16437..17216)
                     /locus_tag="ACL72M_001430"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGS0716546.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17203..18054)
                     /gene="ylqF"
                     /locus_tag="ACL72M_001431"
     CDS             complement(17203..18054)
                     /gene="ylqF"
                     /locus_tag="ACL72M_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGS0716547.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18308..23521)
                     /gene="zmpD"
                     /locus_tag="ACL72M_001432"
     CDS             complement(18308..23521)
                     /gene="zmpD"
                     /locus_tag="ACL72M_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease D"
                     /protein_id="HGS0716548.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(23565..>28235)
                     /locus_tag="ACL72M_001433"
     CDS             complement(23565..>28235)
                     /locus_tag="ACL72M_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS0716549.1"
                     /translation="IVEPEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKS
                     SALINMNFITDSSKVTGVGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYE
                     WVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLN
                     DKLNVHGYPARKYTHLKDATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGV
                     HQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKK
                     LELRNISSVELYSKDGNKYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDT
                     KDNRDVYKIVASANSLIQHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPN
                     GTFRLGATMDAREVELPDGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGAT
                     VEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTIS
                     NSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIV
                     GAVENSALISNSYAEGNLNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTN
                     GNAIAGYNFNSIKANGTYSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQIKEKKA
                     TFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEKVYKNIEKLLPFYNRETIVKYGNL
                     VETSSNLYNKELLSVVPMKDKEVISDINKNKSSINKLLLYYADNTSETLNVNYQTDFS
                     NVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALNSVEYKSEAIRKVLDVSKDVSLTE
                     LYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKVIDNYVIEKIKNNKEALLLGLTYL
                     ERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNVIELGKSGYNNLLAKNNVITYNVL
                     LAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQSIAGS
                     PYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGT
                     DLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEKEDKDT
                     YQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMT
                     HNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPNDPTVTINSILKYDQSEESTRLQV
                     ADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAVAKLDTNQKYDLLRKIENEYKPDP
                     DGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIITRRGYVDEATYKRNGYYTINLFSP
                     IYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMVPYISNQYEKEAKAQGKVITSYGK
                     QIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWARQQKV
                     TIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDFRSSIF
                     ENKK"
BASE COUNT         8391 a         5320 c         5293 g         9231 t
ORIGIN      
        1 ctagtattag acaaaatgct gtggagacat tgactggtct aaaaagtagt cttcttctcg
       61 gaacgaaaga taataacact atttcagcag aagtagatag tctcttggct ttattaaagg
      121 agagtaagta aaggtagcag cattttctaa ctcctaaaaa caggatagga gaacgggaaa
      181 acgaaaaatg agagcagaat gtgagttcta gttctcattt ttttcatgaa aatgtgcaaa
      241 atatagtaga ttgaaactag aatagtatac ctctacttct aaaacattgt tagaaatcga
      301 tttgactgtc ctgttcttat tttactatat cttaacagat agtgtaaata aagataaact
      361 atttactggc taattaatca gttaaacact agttaaggag taatgatgaa aaaaagaaca
      421 atactattat tgatgaccag tctgttggct cttgtcttag gagcatatgg tttcttggac
      481 atattgatcc tggatcattc tcatcaggat tactctttac tgctatttta gaaactgggg
      541 tggtttgatg gaaagtattg gtattggtct tgttatcgtt tcacattcca aacacattgc
      601 agaaggtgtt gttgaactga ttagtaaagt agctaaagat gttccgatta cttatgtagg
      661 aggaaccgag ggcggaggaa ttggaacgag ttttgattaa gtagataggg ttgtttccga
      721 aaatacagca gatactttac ttgccttttt tgacctaggt tctgctaaaa tgaacttaaa
      781 aatggtgact gatttcagtg ataaaagtat catcatcaac agggttccaa ttgtagaagg
      841 tgcctataat gcagctgctc ttcttcaggc tggtgcagaa ctgtcagtta ttcaaacaca
      901 gttagcggag cttgaaatca ataaataagg aattttacta taactctttt tataggtaag
      961 ctattgatta tctcaactat aaaatgttaa gtaaatgatt tcaaaatcag aaagggattg
     1021 ctttatgcag ttccttttta ttttaacagg agtgaaacta tagtgtttct aaattgtgaa
     1081 tcaatcaaaa ctgattgtga tggggctatt ctagctttag aaaccttcaa aaattaaaat
     1141 ttaaggcaat caattacttg gaagagtatg aaagcattta gtttatagga attctaggtc
     1201 tagaattaca catatattta tgaatacggg gtgctcgata gttagtattg ttctattctg
     1261 aaagatttga gctgtcagtt gtatagaaag tgttcgaatt tttttaagtg attaaattag
     1321 ttaattgtat gaggtgcttt atgatataat gttcttaatg aattttcaga aaggaaaacc
     1381 tcaaattgtt ctacaaattt ctactcttcg acctcgacca cactcttctt gattttgatg
     1441 ctgctgagga tgtggctttg acccaacttc taaaagaaga aggagttgcg gatattcagg
     1501 cttataaaga ttattacgtt cctatgaaca aggctctctg gaaagacttg gagctgaaga
     1561 aaatcagtaa acaagagctg gttaacacgc gcttttctcg tttattttct cattttggac
     1621 aggaaaaaga cggtagtttt cttgcccagc gttaccaatt ttatctcgct cagcagggac
     1681 aaacactatc gggcgctcat gatctcttgg acagcctcat tgagcgtgat tatgacttgt
     1741 atgctgcgac aaatggcatt actgccattc agacaggacg tttggctcaa tctggtctag
     1801 caccttattt caatcaagtc tttatctcag aacagttgca aactcaaaag ccggatgctc
     1861 ttttttatga aaagattggc cagcaaattg ctggatttag taaagaaaag acgctgatga
     1921 ttggagattc tctaaccgcc gacattcaag gtggcaataa tgcggggatt gacactatct
     1981 ggtataatcc tcatcacctc gaaaatcaca cacaagccca gccgacttac gaagtctatt
     2041 cttaccaaga cttgctggat tgtttagata aaaatattct tgaaaagatc acattttaaa
     2101 ggagacgagc taatgactac aaaaaagcta atattactat tgaagagtac attgaaatgt
     2161 ctgaagttga ttttaatgaa gctgttaatt atgaatttac atctgacact tgtcaattag
     2221 caaatagtat ttatcaatct ctttttaagt tttttgataa gaaaaatttc tctggcgatt
     2281 taatttttac ttggaaatct ccatcattag tcaaagaagg ggattatatt gggagaaggg
     2341 attcacaagt agataatctt agagtaatag gaaatatatt tccgaattat cttactaatc
     2401 gaaaatatag cctcaatatg aatcgtaatg gctgtatggg agattttcct catgactttt
     2461 ttgatatata cctagatcat gtagcaaaat atgcctacga acaaaaagtt aataatatta
     2521 aagagtatta tcctttaaaa agagcgattt tacaccaata gaatgcattg tattttcgat
     2581 ttttttctaa ttttgacgac tttttagaaa aaaattattt aaagactata tggcaagttt
     2641 ctaaagaaac tcctttttct gaaatggatt ttaatatgtt taaaaatatt tcagaaaaga
     2701 taatcttcga aagaggtagt aaaatgctta atgatttaaa aagtaattat aaaaaatagc
     2761 cagtctttat aaactgtatt cacgtattca aatcgtatat atagtcgatt tattaaatct
     2821 ttagataaac tgtaaaaagt ggtttccata gccacttttt gctataatag aggcagtaaa
     2881 aatgaaggag tcggctatgg aacactcgtc ttggcatgct ttgattaagg cgcaattacc
     2941 tgagggttat ttcgggaaaa tcaatcagtt tatggagcag gtctattctc aggggattat
     3001 ttatccaccc aaggaaaagg tttttcaggc tctcttgaca acactgcttg aagaagttaa
     3061 ggtggtaatt ctagggcaag acccctatca cggaccaggt caagcgcagg gcttgagttt
     3121 ttctgtacct gactctatcc cagctccacc atccttgcaa aatatcttga aagaattgtc
     3181 agatgatatc ggagttaaga aatctcatga tttgacagct tgggctgagc aaggagtctt
     3241 gcttcttaat gcttgtttga ctgttcctgc tggacaggcc aatggtcatg ctggtcaaat
     3301 ctgggagcct tttactgatg ctgtgattca ggtggtcaat catctagata gaccagtcgt
     3361 ttttgtactc tggggagctt atgcacgtaa gaagaaggca ttagttacca atcctcatca
     3421 cttgattatc gaatcagccc atccaagtcc tttgtcggtt tatagaggat tttggggttc
     3481 caagcccttt tccaaggcca atgcattctt aaaagagaca ggacaagagc caatcgattg
     3541 gcttagataa ggagaaaata tgcctcagtt agcgacgatt tgctacattg ataatgggaa
     3601 agaactgctc atgctccatc gtaataagaa acccaatgat gtccatgaag ggaaatggat
     3661 tggtgtgggt ggtaagctag agagaggaga gacgccccag gaatgcgcgg cgcgtgaaat
     3721 ccttgaagaa acagggctca aagccaagcc agttctaaaa ggtgtcatca cttttcctga
     3781 atttacacca gatttagact ggtacaccta tgtttttaag gtgacggagt ttgagggcga
     3841 cttgattgac tgcaatgagg ggacgctaga atgggttccc tatgatgagg ttttgagcaa
     3901 gccgacttgg gaaggtgacc acacctttgt tgagtggctt ttagaggata aacccttctt
     3961 ttcagccaag tttgtttatg atggggataa attgttggat acccaagttg atttctatga
     4021 ataaaggaga aagcagatgc tactaatcaa aaatggtcgt gtaatggatc ccaagtctgg
     4081 tttggatcaa gtttgtgatg tcttagttca agatgggaaa attatcaaaa ttgcgcctga
     4141 gatcacggaa gaaggagcag aaacgattga tgctactggt cttgtggttg ctcctggttt
     4201 ggtcgatatt catgtgcatt tccgtgaacc tggtcaaaca cataaagaag acattcatac
     4261 tggtgccctg gcagccgctg caggtggttt tactactgtc gtcatgatgg ctaataccag
     4321 tccaaccatt tcagacgtgg agactttgca agcagttctc cagtcagctg ccaaagagaa
     4381 gattaatgtc aagacagttg cgaccattac taaaaacttt aatggtaaaa acttgactga
     4441 ctttaaggcg ctcttagaag ctggtgcggc tggtttctct gatgacggta ttccgcttga
     4501 gagcagtaag attgtcaagg aagccatgga ggaagccaaa aaattcaata cctttatcag
     4561 ccttcatgag gaagatccag gtttgaacgg tgttcttggc tttaatgaaa atattgctag
     4621 agaacatttc catatctgcg gtgctactgg agtggctgag tacgctatga tggcgcgtga
     4681 tgtcatgatt gcctatgcaa ctaaagccca tgttcacatc cagcatttgt ctaaggaaga
     4741 aagtgttaaa gtagtggagt ttgctcaggg gttaggtgca gaagtcacag cagaagtagc
     4801 gccacagcat ttctctaaga cagaagcact tcttttaaca caaggtagca atgctaagat
     4861 gaatccaccg cttcgtttgg aatcagaccg tcgtgccgtt atcgaaggtc tcaaatcagg
     4921 tgtcatcaca gttattgcga ctgaccacgc gcctcatcat gtagatgaaa aaaatgttga
     4981 ggatattacc aaagcgccat ctggtatgac tggcttagaa acatccctgt ctctcagctt
     5041 gacctattta gtagaagctg gtgagttgag cttgatggaa ttacttgaaa aaatgacata
     5101 caacccagcc aagctttaca actttgaagc aggttacttg gctgagaatg gtccagcaga
     5161 tatcactatt tttgatgcca aggctgaccg ctttgtggac tcccattttg cttccaaagc
     5221 agctaattca ccattcatcg gtgaaacctt aaaagggcag gttaaatata ccatctgtaa
     5281 gggacaaatc gtctatcaag cttgatagga gttagaatat gaattatttt cgaaaacgta
     5341 gggagagaca agcgaaatct aatagtggaa tttactgtcc cgcagctaat cgttccaaaa
     5401 ttcaatatga aactaaagaa aaagctgacc atgcggttca atatgataac ggaggtttag
     5461 ttagaagcta ttattgtcgt acatgtgcgt gttggcatac tacttcaaaa tctaataaac
     5521 ctccgctaag tttgaaaaac tatggtctga aactctttgg tttagataaa tcagaataga
     5581 aagagaagta tgtataagac aaagtgttta cgagagaagt tagtattatt tttaaaaatt
     5641 ttcttcccaa tcctgatcta ccaatttgcc aattattctg cctcttttgt tgatactgca
     5701 atgacaggtc aatacaacac tatggacttg gctggtgtat ctatggcaac cagtatctgg
     5761 aatcctttct ttacatttct aacagggatt gtgtcagcct tggtgcctat cattggtcac
     5821 catcttggtc gaggcaaaaa ggaagaagtt gcgtctgatt tttaccaatt tatttatttg
     5881 gccttgggcc tatctgtggt cttgctgggg atggtacttt tcttggcacc aataatcttg
     5941 aatcatattg ggttagaagc agcagtagcg gcagtagcgg ttcgctatct ttggttttta
     6001 tctatcggga ttatcccctt gttgctcttt agcgtcattc gttccttgct ggattcgctg
     6061 ggcttgacca aactgtccat gtacctcatg cttttgttac tccctctcaa tagcggattt
     6121 aactatctct tgatttacgg tgcctttggt gttccagaac tgggaggggc tggtgctggt
     6181 ttaggaacat ccttggccta ctgggtcttg cttgggattt ctgttctggt tttatttaaa
     6241 caggagaagc tcaaagcctt acaccttgag aaacgaattc cacttaatat ggataacatt
     6301 aaggaaggag ttcgtttagg tctgcctatt gggggaactg tcttcgcgga agtggctatc
     6361 ttttcagtgg ttggcttgat tatggctaag ttttcgtcct tgattatagc tagtcaccag
     6421 tcagctatga acttttcaag tcttatgtac gcctttccta tgagtatctc atcggctatg
     6481 gctattgtcg tttcctatga agtgggagcc aagcgatttg atgatgcgaa aacctatatt
     6541 ggtctaggaa gatggactgc tctcattttt gcggccttca ccttaacctt cctttacatt
     6601 tttaggggaa atgtggccag tctttatggt aacgacccaa aatttatcga tttgacagtg
     6661 cgttttttaa cttatagtct tttcttccag ttagcagata cctttgcggc gccgcttcag
     6721 ggaattttgc gggggtataa ggatacagtt attccttttt accttggttt gcttggttat
     6781 tggggcgtag caatccctgt ggctacgcta tttgattccc taacagattt tggagcttat
     6841 tcttactgga tcggcttgat tattagtttg attgtgagcg gggcgctcta ccgttggcgt
     6901 ttaactgtga ttatgaagag atttgaatct ttagcaaaat ccaaatgcta aaaagtttgt
     6961 gaaaaaatat tcttgacaag aaaatccctt gttttcacgg ggttttcttt tttattttgt
     7021 gaaatttctt ttagaaaaac tttgacagta tttgccaaaa gcggtaaaat agtaaggtaa
     7081 gaagaaagtt agaaaggcaa gaagatgtca actttagata aaaatctttt gctagaaatg
     7141 ttccgtaaga tggaagaaat ccgtcgcatg gacttaaaaa ttgcacaatt agtaaagaaa
     7201 gggaaagtgc caggaatgac gcacttttct gttggtgaag aggcagctaa cgtgggggct
     7261 atgttagctc tcaatccaga tgatctgatt acctcaaacc accgtggaca cgggcaagct
     7321 attgctaaag ggattgacct caacggaatg atggctgaaa tccttggtaa atacactgga
     7381 acctgtaaag ggaaaggtgg atctatgcat atcgctgacc ttgatgctgg gaaccttggt
     7441 gccaatggta tcgtaggtgg tggtatgggg atcgctgtcg gtgcagccct cagtcagcaa
     7501 atgcaaaata ccggtaaaat cgttgtctgc ttctttggag atggtgcgac caatgaaggt
     7561 gttttccacg aagcagtgaa catggcttct atctggaacc tgccagtcat tttctattgc
     7621 attaacaacg gttacggtat ctctgcggat atcaagaaaa tgaccaatat agaacatatc
     7681 catcaacgta gcgccgctta tggaattcct ggaatgttca tcgaagacgg taacaatgtc
     7741 atcgatgtct atgaaggatt tcagaaagct gtggaccatg ttcgcagtgg caatggtcca
     7801 gtcttgattg aaagtgtaac ttatcgctgg ctcggtcact catcatctga ccctggtaaa
     7861 tatcgtacgc gtgaagaagt ggaattgtgg aaacaaaaag atccaatcga aaacctccgc
     7921 aattacctta ttgaaaataa cattgcaagt gccgaagaat tggaagaaat ccaagcgcaa
     7981 gtaaaggaag cagtagaagc ttctgttaaa tttgcagagg aaagcccatt cccaccgctt
     8041 gaatcagcct ttgaagatat ttacgcagac taaggagaaa gagataaaat ggaaacaaaa
     8101 acaatgtcct tccgtgacac cattatcctt gctatgtctg aggaaatgcg tcgcgatgaa
     8161 aatgtgttct tgatgggaga agacgtcggt gtcttcggag gagacttcgg tacttctgtt
     8221 ggaatgcttg aagaatttgg tccagaacgt gtccgtgact gtccgatttc tgaagctgcc
     8281 atctctggag cagcagcagg agcagccatg acaggacttc gtccaatcgt cgatatgacc
     8341 ttcatggact tctctgttat tgccatggac aatatcgtca accaagctgc taaaacacgt
     8401 tacatgtttg gtggtaaagg tcaggttcca atgactgttc gttgtgcagc tggtaacgga
     8461 gttggctctg ccgcccagca ctcacaatct ctagagtctt ggtttactca cattccagga
     8521 cttaaggttg tggcacctgg aacacctgcg gacatgaaag gcctgcttaa gtcttctatc
     8581 cgtgataaca actcagttat tatacttgag tacaagtcag aatttaacca aaaaggggaa
     8641 gtgccagttg atccagacta cacaattcca cttggggttg gtgaaatcaa acgccaagga
     8701 acggatgtaa cagttgttac ttatggaaaa atgcttcgcc gtgtggttca agctgctgaa
     8761 gaattagcag aagaaggaat ttcagttgaa attgttgacc cacgtaccct tgttccgctt
     8821 gataaggata tcatcataaa ctcagtgaag aaaactggta aggttgttct ggtcaacgat
     8881 gcccacaaaa caagcggcta tatcggtgaa atttcagcta ttatttcaga atcagaagca
     8941 tttgactatc tagatgcacc aatccgccgt tgtgcaggag aagatgtgcc gatgccttat
     9001 gcacaaaacc tagaaaatgc aatgattcca acagttgaaa gtatcaaaga tgcaatccga
     9061 aaaacttata acaaagaata gggttacata agataagtta tgtaaataaa ataaagctga
     9121 cgagaaactt tgtatctttt aggtgcagag ctcttcgtca ttaatatctt agattagagc
     9181 acgggctaaa agatcggaaa aaagataaat ctccttggct tcatcgaagc catcgtcgat
     9241 ttcctatttt tcagtcgctt ttgacgccct ttgtatcata aatagaattg gagaggtcat
     9301 ggctgatgac aagctaagag cgactcctgc agctagaaag ttagcggatg atttagggat
     9361 aaacctctac gacgtttctg gctcaggtgc aaacggtcgt gtccacaaag aagacgtgga
     9421 aacttataaa gacacaaacg tggttcgcat ttcgccactt gcaaaacgaa ttgccctcga
     9481 acataacatt gcttggcagg aaatccaagg aaccggtcat cgtggtaaaa tcatgaagaa
     9541 ggatgttttg gccctgcttc ctgaaaatat cgaaaacgat agcatcaaat ctcctgctca
     9601 gattgaaaaa gtggaagaag tccctgataa cgtaacacca tatggtaaaa tcgagcgtat
     9661 tccaatgaca ccaatgcgta aggttattgc ccaacgcatg gttgaatctt acttgactgc
     9721 gccaaccttc accctcaact atgaagttga tatgactgaa atgttggctc ttcgtaagaa
     9781 ggttcttgag ccaatcatgg aagcaactgg gaagaagact actgtaacag accttctttc
     9841 gcttgcagtt gttaagactc ttatgaaaca cccatacatc aacgcttcat tgacagaaga
     9901 tggcaagact attatcactc acaactatgt caatcttgcc atggcagttg ggatggataa
     9961 tggattgatg acacctgttg tttacaatgc tgagaagatg agtctttcag aactggttgt
    10021 agcctttaag gatgttattg gccgtacctt ggatggtaaa ttggctccaa gtgagttaca
    10081 aaattcaaca ttcacaatca gtaatttggg aatgtttggt gttcagtcct ttggtccgat
    10141 tattaaccaa cccaactcag ctatccttgg tgtcagttcg acaatcgaga agccagttgt
    10201 cgtcaatggt gaaattgtga ttcgcccaat catgagttta ggattaacca ttgaccaccg
    10261 tgtcgtagat ggtatggctg gtgctaagtt tatgaaggac ttgaaagagt tgattgaaac
    10321 gccaatctca atgttaattt aagagcaaga gtattcattt ttaagatata gataaaggaa
    10381 ggaagacatg gccttagaag taattatgcc aaaagccggc gtggatatga cagaaggaca
    10441 aatcgtccaa tggaataaaa aagtcggaga atttgtaaaa gaaggagaaa tccttttgga
    10501 aatcatgact gataaagtca gcatggaatt ggaagccgaa gaagatgggt acttgattgc
    10561 cattctcaaa ggagatggtg aaactgtccc tgtaacggaa gttatcggtt accttggtga
    10621 agaaagggaa aacatcccaa cagctggagc agcatcgcca gaagctagct ctgtacctgt
    10681 agcaagtacc tcaaacgatg atgataagag cgatgatgct tttgatatcg ttgtgattgg
    10741 tggaggtcct gctggttatg ttgcagccat taaagctgcc caattcggcg gtaaggttgc
    10801 ccttgttgag aaatctgaac ttggtggaac ctgcttaaac cgtggatgta ttccaaccaa
    10861 gacctacctt cataacgctg aaattattga aaatatcggt catgctgcaa atcgtggtat
    10921 cgtgattgaa aatcctaact tcactgttga tatggaaaaa cttttagaaa ctaaatctaa
    10981 agttgttaat actcttgttg gtggtgttgc aggacttctt cgtagctacg gagttactgt
    11041 tcataaagga attggtacaa tcactaaaga caagaacgtc ttggtaaatg gttctgaatt
    11101 gcttgaaacc aagaaaatca ttcttgctgg tggttcaaaa gtcagcaaga tcaacgtccc
    11161 tggtatggaa tctccacttg tcatgactag tgatgacatt cttgaaatga acgaagtgcc
    11221 agaaagcctt gttatcatcg gtggtggagt tgtcggtatc gaactcggtc aggccttcat
    11281 gacatttggt tcaaaagtga ctgttatcga aatgatggac cgtatagttc cagctatgga
    11341 tgtggaagtt tctaagaacc ttcgcttgat tcttgagcgt aaaggaatga ccatcttgac
    11401 tggtactaaa ctgcaagaaa tcattgagga aaatggtcaa cttcgtatca aggttgaagg
    11461 aaaagacgat atcatcgcaa gcaaagctct tctttcaatt ggtcgtatgc cagaccttga
    11521 aggtattgga gaggttgagt ttgaattgga tcgtggttgt atcaaggtca acgaatacat
    11581 ggaaacttca gttccaggca tttatgcacc aggtgacatc aacggtacta agatgttggc
    11641 tcacgcagct ttccgcatgg gtgaagtttc cgctgaaaat gcccttaaag gaaatcatgc
    11701 agttgccaaa ttgaatttga ctcctgcagc catctacact ctccctgaag tagcagcagt
    11761 aggtttgaca gaagaacaag cccgtgagaa atacgatgtt gccatcggta agtttaactt
    11821 tgctgctaac ggtcgtgcta ttgcatctga cgcagctcaa ggtttcgtaa aagttatcgc
    11881 tgataagaaa tacggagaaa tccttggtgt acacattatt ggtcctgcag ccgcagaatt
    11941 aataaacgaa gcatcaagca tcatcgaaat ggaaatcact gttgaggaaa tgctgaagac
    12001 catccacggg cacccaactt actctgaagt gatgtacgaa gcgtttgcag atgttctagg
    12061 aatggccatc cattcaccta agaaaaaata aaacgaagat agattagact ggaaggttat
    12121 ttccagtttc tatcatataa agtaaaggga tatcatgaaa tacattatca atcattcaaa
    12181 tgacactgct tttaatattg ccttggaaga atacgccttt aaacaccttt tggatgagga
    12241 tcaaatcttc ctactttgga ttaacaagcc atctatcatt gttggtcgtc accagaacac
    12301 tatcgaagaa atcaaccgtg attatgttcg cgaaaatggt attgaggtag ttcgccgtat
    12361 tagtggtggt ggagctgttt accacgattt aaataacctc aactacacga tcatctccaa
    12421 agaagatgaa aataaggcat ttgacttcaa gagcttctca actccggtta tcaataccct
    12481 ggctcaactt ggggttaaag ctgagttcac aggtcgtaat gaccttgaga ttgatggtaa
    12541 gaagttctgt ggcaatgccc aagcctatat caacggccgt atcatgcacc acggttgctt
    12601 gctctttgac gttgatttgt cagtcctcgc aaatgccctt aaggtttcaa aagataaatt
    12661 tgaatcaaaa ggtgtgaaat ccgtccgtgc ccgtgtaacc aatattatca atgaattacc
    12721 aaaaaaaatc acagtcgaaa aattccgtga tttactcttg gaatacatga aaaaagagta
    12781 cccagagatg actgaatacg tcttttcaga agaagaattg gccgaaatca atcgcatcaa
    12841 ggatactaag tttggaactt gggactggaa ctatggtaaa tcacctgaat ttaacgtccg
    12901 tcgtggaatc aaattcacta gtggtaaggt tgaagtcttt gctaacgtta ctgaatcaaa
    12961 aatccaagac atcaagattt atggtgactt ctttggtatt gaagacgttg ctgcagtaga
    13021 agatgtcctt cgtggggtga aatacgaacg cgaagatgtt cttaaggcgc taaaaaccat
    13081 tgatatcaca cgctacttcg ctggtattag ccgtgaagaa atcgctgaag cggtagttgg
    13141 ataaatcaaa aagaagttgg ccaactaacc aacttctttt tttgatattt atttacataa
    13201 tttaaaatac gtaaaatcat aaactatcca gagcattctt ttgttcatca ttaacaatat
    13261 gggtatagag gtcagtgact tgtgtgctgg catgtcctag ttggtgactg actaaaactt
    13321 gtgatttagt agcatcatag agcctagttg ctagtgtatg gcgcagttta tggggtgtta
    13381 cacgtacttt aaaatcctct gagtatttag caaccatttt ctcaacgcta gaagcatcga
    13441 tacgattagg aacacctctg tagagagtta aaaaaagggc tgtatctgtt ttttccgttt
    13501 tatagcgttg attccgaatg gccagataat tctctaaata aggtttagca aaagcagcga
    13561 cattgactga gtcacgtttg ccaccttttc gagtaacatc aataaccatc atttttagat
    13621 tgagatctct tagatctaga ttaacagctt cagataagcg aacaccagat gccaagagaa
    13681 gggcaataat ggctaaatct cgttctttat ttttgttgaa tgatgagaga gctcgatttg
    13741 aaagctgttg tgggtgctct tgatcgatat aagttagaaa accttctgtt tcatcaccta
    13801 gaaagagttt ttgcttgata ttttcagctc tggcagcaag ggtttctttc tttttcttgg
    13861 ttgaaacttt tttcattaca ttacgataga aataaggttc cccctgatcg ttttcaacct
    13921 cctcggttag atacttgtaa agactagaaa gtgctgataa ggttcgattg atagttgtct
    13981 gtgaaacacc ttgttttgtt gtattagcat tcagcaaggg acgttcacgt agataaagga
    14041 taaaggattc catgtctttc ttagacatat tttccaaaac tgataaagga atatcggata
    14101 ttttatcagc gtttgaaata ccagactcca aaacccagct gaaaaatcgg tcatattcct
    14161 taaggtattc gtacagggtt gtaaaactgt agggcacagc cagtttagat tggtagtatt
    14221 ccagaacata ccagggcatg agttgtttta gtttgtcgat tcgttccagt aaaatctcac
    14281 gtttcatgta ttttctccat aattaagtat actagtagta tagcatagac ttgtatattt
    14341 ttcaagaaaa ttatagtttt tcagaaagat gctataggag tttttcaaag tgataaaaag
    14401 acttagacct acaaacaaaa cagaataagg aaaataataa aaatctcacc cactaaactt
    14461 ctgttaatac tacataactg aagagctata taaggagcta tgagatacaa aacacattgt
    14521 ataatagatt gaaactagaa tagtacatct ggacttctaa aacattgcta gaaattgatt
    14581 tgattgtcct gattgtttta tcctatttct atttcatttc tctatataat tgctattgtt
    14641 ttctttttca tgattttaat cttactgtac agatttgata cagtaaactc ctttctagct
    14701 ttatacttta tcatttctaa cttaattata gtcttatttt taataaagtt caattattta
    14761 tatgtaaaat tcctcatcag taaaaaataa ccgatctcat ttctgagaat cggttttcta
    14821 aataaatcaa actgatcatt tacataacat aaattatgta aatgatcata ctacaacaac
    14881 aaatctttga cttttccaat ttcacttttt ggaataacca ggtgaatcat atcacccaga
    14941 tacattctgg ttgagccgtt aactgtttgg ctcttgccat tatggacttg agttgtgatg
    15001 aggacgttgt gtggtaagtt gagttcatga acttgtttcc cagcaatttt atcagaaact
    15061 ggtatttcga taagtgtaac ttctccttcg ctagatactt cttctggaag cattttttcc
    15121 agcatggctt catagactgg cgtacctttg agcaaatcca tgataatata agaaacaaga
    15181 gtgacaagac caagtggcat aaggttgcga atatctccta ccatctcagt tacgaggatc
    15241 atagcggtta agggagcttt tgatatggct ccaaaatagc cactcattcc tagaatgaca
    15301 aatataggga attgctcttg actgacaagt ccaagattga cacagataac accaactaag
    15361 gcaccaagca aagaaccaag agctaaaatg gggaggaaaa ttcctcctgg cagtccactt
    15421 ccatagctaa tcatactcca aataaagcgg attaaaaagt aagctaataa aacttggaaa
    15481 ctaaaatttt gttcagttaa agaaaggaca agctgatttc cgccaccaat gatttgaggt
    15541 aagaagattc cgactggtat gataaggata aaagccaaga tgggataata agccctatcc
    15601 aaatggattt tttgaccaat caagtcataa actcttccaa cgtttaatac agctttctca
    15661 tagagaaaac ctgaaaatcc aaggaaaatt cccatgacga gatatatcca atactgatct
    15721 agggtcatgg gaggaatgtt atctggcata tccaatactg gtgtcaaacc gaacatgagt
    15781 agagacacaa agtttgctac gatgctggct gctagagttg agacccagaa aaagcgcgaa
    15841 aaatggtgat agacttcttc tacaacaaag agaagtgctg caataggagc attaaaggct
    15901 gcggctaaac ctgctgcagc tccactggca atcaaggaac gttcctctac tggactggat
    15961 ttgagccact tggcaattcc tttaccacca actgctccaa gttgaatact gggtccctct
    16021 cgacccagca tgagtccact ggcaatagca agaataccta gcacatattt tttccaaaga
    16081 atgccccacc agttgaggga catgaggcct ttcagttcgg cttcgacttg aggaattcct
    16141 gagcctttaa tatctttttc tgaccgtgtt agtttggcac tgagccaaca gatgagtata
    16201 taaaacaaaa ccagtacaaa aagattgcgc actaagtacc cttgatcttg ataaactcct
    16261 tgtatcaggt ggaagccctt ttcaattaag aaacgaaagg atccgacgat aattccaacg
    16321 atgaggccga caatgattcc tcgaccaact tgggatagta tagtgctgga tgcaaaggcg
    16381 aattctttct tagaacggac tatttccgac tgttcctcca tggtatttcc tttcaattaa
    16441 ctttcttttt tacctaaaac cagtgattta acgggttcaa agctggttcg gtgaattggg
    16501 gtaactccta gttttgtgag gccttccaga tgtttagctg tgccatatcc tgcattagta
    16561 gcgaaatcat agccagggaa ctgctgatcg tattccttca tcaattcatc acgtgttacc
    16621 ttggctacta tagatgctgc tgcgatagag agggagttgg catctccttt gataatggag
    16681 gtttgtgaaa tgggcaagtc cagtttcatg gcatcaatca aaaggtgctc tggttgaggg
    16741 ctgagctggg agattgcttc ttgcatggct agtttggttg cttcatagat gttgacttgg
    16801 tcgatgacct gattatctat gataccaatt ccaatcgaca aggcttggtc ttgaacggct
    16861 tggaaaatct ccagatgttt ctttttagga attttcttgc tgtcgttgag acctttaatc
    16921 ttacaatttt taggtaaaat gacggccgca gcgactacag gaccagcaag aggaccacga
    16981 ccaacctcat caatacctac aattaaggtc aatccttgct tataaagttc tttttcataa
    17041 gaaagcatgg attccaagcg caaattttca tctaattcag cttgaatggc tcttttacgc
    17101 ttgctgattt ccttttgaac tcctgagcga ttatcctttt caagctctaa aaaaataggg
    17161 ctttctaact ccttgactgt cacaaggaat tctttgattt ctttaatcgt tgccatcgag
    17221 gtcttccaat gtatctaagg tatagttacc gagtttgcca tcacggactt ccttcacgaa
    17281 gagactgtaa aaacggtcat agtcatcacg gaaaccgagg gcgcgggtca tatccataat
    17341 aatcacaggc gcttcttctt caattttcat ttgtttgaag cgttcagcca gcttttctgg
    17401 ataatgttct ttgaaataat tgataccaaa aatggtaacc tcatccatag gaagcaactg
    17461 atccttgata gctccagtca atgccaactt aagtgcaaca gtttcatcct caaacttagg
    17521 ccagagaatc cccggtgtat ccaagatttc caggtcttta ttggttttaa gccattgttg
    17581 accttttgtg acccctggct tgtttccaac aacagcaatc tttttaccag ccaaacggtt
    17641 catcagagtt gatttaccag cgtttggaat cccgataatc atagtacgca aggtttcaat
    17701 ctgaatccca cgttctttct ggcgagcaat cttatcagcc atgagcttct tggccgcatc
    17761 tgttacaact tttacagtca cttgctcctt ggagttgata gccagagttt ggattccttg
    17821 tgattcaaaa tactgacgcc attccttggt cattgctgga tcagccaaat ccgccttatt
    17881 taaaatcaag agttttggtt tatcaccaac aatcttggtc aacataggat tttgactaga
    17941 tagaggtaag cgtgcatcca ccaaaatcgt tacaaaatca acaaatttta aattttcctg
    18001 cacctgtcga cgcgctttag acatgtgacc aggaaaccat tgaatagtag ccattgagtt
    18061 tttttccttt cgtagcaagg gtttagagat cctattttat tttactatcg tttgaacata
    18121 aagggttctc aaatgaatga tgttcaaaca gttttttgtt ttatggcata gaaatctacc
    18181 ttatattata tcatgccttc tttattttgt ccgatgatag cctttcaagt accctatata
    18241 gaaaaaagcc atcaaatgat gacttttcag agggagcaaa aaactgttcc ttctatattc
    18301 taaacattta aatgtcttct ttaaacagtt tattaaagaa accgtctgtg tttttaagaa
    18361 gggctttgaa gaccttagat ttaagagcaa cagtgtgaga gaagtcatct ggtttcttca
    18421 aatcttcttc aactgcttta tcaaataaag gccttaactc atcatagtta ctgatatgga
    18481 cgccatcaat atcgatagcc tcaaaacctt tcttagcttt agcaagaact tccccgtacc
    18541 aatgtctctt ccactcttca agagtattaa agtttccttt cgatacttta ttaattatta
    18601 gcttatcgct tagtaaaccg tggttgtttt tatctgcttc tgctttgtat ttatttgata
    18661 cataactaat aaagccattt tcataaccat aatagcccca catacggaaa gcattgtgct
    18721 taaatgataa tgaaccagga gcaccttgac tcgtattccc accgtaaatt cctgccatca
    18781 tattgacatt tacgtaagct gagtttggtg taaaatcttc tggtctataa cgtccattac
    18841 ctggatttcc atgttttgtc atgaagttat tatccactaa atcattgacg ctagataaag
    18901 tcattacctt ttcttcatct ttcaaatcac ggatactatc ccattggttt ggacctaaaa
    18961 gatcattata ctgaatctta gagcgcattt ctttgtcaat cttcttgaac cacttactat
    19021 tgtctccttt aattttagga agtacagcat cagcttctac atgatcaagc aacatcatag
    19081 cttcattgta gtttctcatg tagcggtcaa tgtcatcacg tgtctttaat ttgtcaggat
    19141 ctgggttgta ccattggtta ccatcatttg gacgatggta agccatgtta attccaagtg
    19201 cgccgtattc accattagtc gttgagctgt caggtgtttg caacatacct tgagcatagg
    19261 cttcaacgtc tgtaccttga cgatgcttat gaccaccgaa gtaaagcatt ctatcgttta
    19321 cgtgtgttgt ttcgtgagta aaggctgaaa taccaaatgg gctaatcata tccgtcacca
    19381 taaacaagac cttgtcatca ttatttggat tagggaatat tgatgccata gcgcccatac
    19441 gccagtctct atcatggtgt cgccatgttg gaccatataa ttcacgaatt ggagctatag
    19501 ggttaccttt actgtcaaat cctcgacgac ctacaggaga accattgtag gtctggttat
    19561 cccaaactgg tgtcggtacc atattttgac tcttaagaag tctatcacga acattaggca
    19621 gagctaatct ggaccagaaa tctaaataag tttgttgagc atgtgcaact tcatcaatct
    19681 tagttttgaa ctcattacga gcttcttctg tatgttttcc atatttctca aatgaactgt
    19741 acgccatcgt gttatatgtt gaaattaaga acatatgggc atctttaagc gttagaagtg
    19801 gtaaaatcat acgaccatga acaccgttat ctaaaccatc gaacacacga tgacgtttat
    19861 ctttcaactc tgtatttgtt gtcttaggtt ctgaaacata aacattctta gctgagtgga
    19921 taaaccaatc attgatgtct ttatcctctg taaacagacg catgttgtat tctaagaagt
    19981 tacgcaaatt acttttacca gtattacctg cgatgatttc acggtaagca tcctgagtcc
    20041 gatccccttt caagttcttt tcacttgaac cgatgttgat gagtctgtca ataacacttg
    20101 gtgttttacc ataaaaatca ggtttgaaca tcatgatgtt ttttatactt atgtcaccgt
    20161 atttgatatc atagtaacga ttgagataag tcagagccat catgatttta gctttattgg
    20221 tttccacttt cttgagaagt gattttatcg cagcttcatc accattcaat tgatggtctt
    20281 cattttcgac caaggatttg actaacttat ctagattttg cttcacttcg gcaaagcttt
    20341 cttctaagta tagatcttta atataaccat tcttacgttc atccgtattc tctgcaggtt
    20401 tatcacgtct actcattaaa tctcttactt cttgtgaaat caattccaca cttgataatt
    20461 gagatttaac atcagcaatc aatttatcac gatttttaac aaccatattc ggtgtataaa
    20521 caacatcacc aagaccagat acactatatt cacgcacttg ttggacttta gaatcagtat
    20581 tcttagtaac atccatttct tccttagtac catcagcata gtgaaccata atcttatcaa
    20641 tatctgataa atcggtcacg aattgaccat ccttcatccc cgtaacagaa aggacttctt
    20701 tcttagctaa gtttgaatct tctgcaagtt tgttaccttg gttgacaatc cattctttat
    20761 tataaaatgg ttgaagtttc tcaatattac gataagctaa atcacgttcg gatttgtagt
    20821 cttgagttga cttatattca tcttctcttc tggttaaacg atttaagcga ttgaccacag
    20881 gttcgttgat ttcgtattta tcagcagtaa gtccaaaatt tgcaattctc ttattagctt
    20941 catcttgact aatttcttta attttgtcac gagaacgttt gtatgaatgc ttacctgaac
    21001 tgacaccttt gacaacaaag ttacgctcta accagccatt tgtgaaataa ccaccatcgt
    21061 agtccaaatc ggaagaacca aagaactctt caccattttc aactctcatc attgaaatat
    21121 tatcttcaag tttaccaaaa ggaagattgc tattgataaa tccacctgtt tcaaacaaaa
    21181 ctttagtctt aatggttcct ttggtgactg atttacgaat tgaaccgtat ttaccaattc
    21241 ccatagagtc gttaccatta tctgttttag caactaaacc acctatacgg gctctgttag
    21301 caacaatatc agcctcgaca tatgcttttg caagattacc tctccaaatc tcaccggcaa
    21361 tgccagccat atattgacct ttatcaccaa cacctgtaag attaccgatg aaggctacat
    21421 ttgtcaactg accaccacta tcgattttat tgacgatacc cgcaatattg ttattagcaa
    21481 ctacattacc agttacctta acatcttcaa cagttgcatt tttcaccata ttggcaacag
    21541 gtgctattcc gtcagcccaa ggcatattga tatccacatt acctaaatta atatttttca
    21601 cagaaccatt ttcaacacgg tcaaataagg gacgggcaat gttatgaatt gtatattgtt
    21661 taccatcaac acttgataga tgtcccttaa acgtacctgg aacatattgt ttgttaggtg
    21721 ttggtacatt cgttgcattc aaatctgctc cgattttaaa tgtaccattt ttatcagcat
    21781 tcatggcatc tactaactct ttaaagttat aataaacgtc atcaactttt ggaactggtt
    21841 tttcaatata atgaacatac ttgttacgaa ccttcgttgg gtctgtatgt tgaatcaaat
    21901 cttgagcttc ggcagtgatt ttataaagtt tcttaccttc ttcagtcact tcttcaattt
    21961 tatcaactgc taaacgtgtt actttattat cacgactagt aatttttaag tacattttct
    22021 tcacatcttc atctgaaggt ttttcagtca taaaatcact aggtgtttca gtaccatcgt
    22081 catttacctt cactaaatta gtagatgcga tatttttaat ttcaactttt ttcaaatcca
    22141 agcgaagtgg tttctcttct aatgttgcag tttcttctcc cttgccacgg tcataggtca
    22201 tagtggtctc tatcttatag tccttgtaga attttaaatc ttctacctgc ttatctaatt
    22261 gctctgaagt caaatctact gttttgacaa tttcatttcc atctttaatt gtcgcagtaa
    22321 ttttattgat tgtgactcca tctgtattaa ctaaatgata agaaagagtt gcggatcggt
    22381 ttaatacatt tgtatttgtt ctatctaagg tcaaaacagg agccgttttt tctttaggtt
    22441 tttctttggt accttttaca agaattttag gcttcatttc tttcaaaata gttactgttt
    22501 caactgggtc actgattttt ttgccatgta actcttcata gctagtaaca atttgacgtt
    22561 cgccatcctc accaacttgt ctaacagaat catcgcctat aaatttgcta ggatcagatt
    22621 cttctatagt ggttttagga atagtctctg tccgaatatc ggtatgtaaa gaaggcaact
    22681 cttctctttc tgatgcaact tctgaaactg tagatattgg ttcagtatac tctggaatgt
    22741 cgctaacagg tggctcaatc aagtttccat tttcatccac tcctgttgta cctactggct
    22801 cagtatattc tgggatgtcg ttaacaggtg gttcaatcaa gtttccattt tcatctactc
    22861 ctgttgtccc tactggttca gtgtatgcta gtttctcatg aacttcaggc tcaacaaggt
    22921 ttgcacctat tggttgcgta tagtcaggct tctcatgaac ttccggttcg cctttctctg
    22981 ttacaacttt gggttgctca actggcgaaa cagttgatgc tggagaaacc gacgaaacag
    23041 ttttatcatc aagctccaag taaccaacat atctgtaacc agaaatttgc aacacaccat
    23101 cacgtccaga ctcatggatg ttagcattca aattaagtgc tgaagcagtt gatagtgtaa
    23161 ctaaacctgt cgcccctaca atcaaaaatg tagctatttt tttatttcta ttatcttttg
    23221 tgataatcac aataagactc ccgatagcta acaaacccaa tgcagtcata atagattgag
    23281 aacttcctgt gtttggtagt gcgtcttttt cataatccaa agcatatgac tctttggatt
    23341 catcaggtct accttgtttg agttgatcac gttcagtttg tgtcaaacta ctataatcta
    23401 agtaatgata agtcgatgca ccaacaactg acggtgcaaa taaaagactc cccaagaata
    23461 ccgaaccaac aatacccttt attttccgaa tggaaaattt atcttttttt aataatgaca
    23521 attctaatcc tccaccttca ctttttattt cctaatagta aacactattt tttattctca
    23581 aaaattgaac ttctaaaatc accggtttgg tcaagataag ctttaaagat tgcttttttc
    23641 agtttaagaa ctctactatt tgtctcagga tataatttgg caacttcatc ctcagcatca
    23701 aattttactg catcttcaat cattttttca agtctattaa tattatcaat agtcactttc
    23761 tgttgtcgag cccaagaacc gtttggatcg ataaaactaa ctttatttaa ctttccaaat
    23821 ttatcttctc tttctttata catatctttc ttgaaatcta tccaagaatt atactggtta
    23881 ttaaatactt ttgaaagaac aatttcatca gtaactaaac ctatttgttt accatatgat
    23941 gtaataactt ttccttgagc tttcgcttct ttttcatact gattagaaat atatggaacc
    24001 ataccgtctt tgtacccctt ggctgccaat aactcaaatg caatacgtcg tcccattaaa
    24061 tctcctggtg ttcctatttt actgctcaat gctgaataaa ttggtgagaa tagattaatt
    24121 gtatagtagc cattccgctt ataagttgct tcatctacat aacctcttct tgttataata
    24181 tcatgttcta tcaaactgtt aaatgtagtt aatttagtaa gttcttctgg ttttaatcta
    24241 cgtacaacat tcgttgcata aacagaattt ccatcaggat caggtttata ttcattttct
    24301 atttttctta ataaatcata tttttgattt gtatctaatt tagctacagc tttaccttct
    24361 agtatttcaa gcatgtatat tacatcaaac atattatgca tatacttatt tagatcatca
    24421 acacttccaa atcgttgagt tggatctgct acttgaagcc ttgttgattc ttctgattga
    24481 tcatatttta atatggaatt aatagtgact gttggatcat taggatgatc aggagcttgt
    24541 agcagtcctt tagcataaaa ctctggtcca agtccatttc gtcttccata gcctccaaga
    24601 taaatttctc tatctgagtt atgtgtcatt tcgtgtgtat aagttaccgc accatcttta
    24661 tcaagcatgc gatatgccat ataatagaat gcatcccctg tagcatatgc tccattagaa
    24721 ttatgaacaa cattatttcc cgctggaccg aagaaatgtt ttatagctgg atgattagtt
    24781 tcaaaagttg cttgatatgt atctttatct tctttttcat ctgtaccaaa tctaaatgca
    24841 tcatagacta gaacacttct atataatttt tctttatttt tatcatctag tattctatac
    24901 caataatcat agtgatctct aaatctaaca gccgcttctt tagctttttt ctcaacatag
    24961 tcatttaaat cagttcctgc tggatgttct ttacttctat atctatcata agcaccgaaa
    25021 cctatagtcg aaatgttggc tataataaac accgattttt caggtaatgt taatagcggc
    25081 aacaccatac ttggatattt ccaagatggg ctagttaatc tatcatatac tccaattgaa
    25141 tatggactac cagctattga ttgcttatca cttacctctt taatagtaga tttttcttct
    25201 acaatatatg ctttagtttg ttctttaaac cactcattat ttgttttatc tggtacaaat
    25261 gcttttctat atttctctaa tgcatcaaat aaattattag tcttataatt tttcgctaat
    25321 aaaacattat aagttataac attatttttt gctagtaagt tattatatcc cgatttacct
    25381 agttcgataa cattatctaa cgctgaacta tttgatttac cgaagaaatc caagtggtac
    25441 atgactaaat ctttcgcttt tgtatcacga tatttgaagt cgtaccaacg ctctaagtat
    25501 gttaatccta gaagtaaagc ttctttatta tttttaattt tctcgattac ataattatct
    25561 attaccttat tgttattttc agctattgca gcatctgcag taagaagttt tgtcaaacta
    25621 tctttcaaat tagtttttgt ggtattgaat tgttcttcta aatataactc cgttaaacta
    25681 acatccttag aaacatctaa tacttttcta attgcctctg atttatattc tacactattt
    25741 aatgctggta atacttcatc taaaatattt tgataattgc gaagtaatgt attcggtgta
    25801 taaattaagt ttgtaccgcc tattctatac tctgctacat ttgaaaaatc agtttgataa
    25861 tttacattaa gtgtctctga tgtattatcc gcgtaatata gtaatagttt atttatactt
    25921 gatttatttt tgttaatatc actaattact tctttatctt tcatagggac tactgacaat
    25981 aattctttat tataaagatt actacttgtc tctactaaat ttccgtactt aacaattgtt
    26041 tctctattat aaaacggtaa tagtttttca atatttttat atactttttc ttttgatgaa
    26101 tcagcattct caagattttt atagtcagtt acatatctag aagagaaatt aaaatcttct
    26161 gttttaatag tatttttaga tacaaaagta gcttttttct cttttatttg tgcatcttct
    26221 aatacttctc ctctttgaac agtagaatcc ttagttaaga tttcatcatc ttcttgtact
    26281 acgttcacaa ccttattatt tttattactg tatgtgccat ttgcttttat actattaaaa
    26341 ttataacctg caatagcatt accattcgtt acattaacat cgcttagtac attagaaagt
    26401 cgaccggatt tttctaatcc tccaaccgga tcccaaagat taccaactac tccaccaacg
    26461 tttgcaaaac gttgaacatt atttagattt ccttcagcat aactattact aataagcgca
    26521 ctattttcta ctgcaccaac tattccacca atagactggt ctccttgtgt tgcatttgaa
    26581 gataaatcga ttgatgcgaa cgacttatct attaatcccc tcggaccaga aagtttgcct
    26641 actaaacctc cgatttgata actagcaact gttttatatg tattagttat tctacctgta
    26701 tagctactgt tagaaatagt agaattatta acttgtgata ctaatcctcc tatgctacgt
    26761 tccccagcta tcgctccatc agcatgaacg ttatcaatat gagtattgtt atttgcttct
    26821 ttcgcaagtg ttgcagtatc gtcctttgcg gaaatattaa catcttttag tgaaagtttt
    26881 tctactgtag caccatttaa ttccccaaat aatggttttt tcaaattata aatagcataa
    26941 tatttctcat tatttgttcc tactaatatt ccatggaata cattattcac ataactttct
    27001 tgaccatctg gaagttcaac ttcacgagca tccatagttg ctcctaaacg gaatgtgcca
    27061 ttaggattgc tattcattgc atctactaaa tttttaaatg atgtatatac cccagtttca
    27121 ctttgctgag tttttggtaa atagtatgta taattttcta gtacattatt attttcatgt
    27181 tgtatcagac tatttgcact tgctactatc ttataaacat ctctattatc tttagtatca
    27241 ttagtaatgc ttgtaactgg tagcatcaca tctttaaagt tctctgattt aactttcata
    27301 aagtaatttt ctgcattact tggtaaagaa gcaagtgaag ttacatgtcg atacttatta
    27361 ccatcttttg aatatagttc tacagaagat atatttctaa gttctaattt cttaataact
    27421 tctttttcat ctttagcgtc atcttttttc tcatctttat gacgataaag ttcatcgtat
    27481 actggtggaa tttcattacc tgctataata ctcttaatcc aagctaattg tgtaggagat
    27541 aaaatcaatc cgcctgagcg attttgtgct ccattttgat gcacaccaat aacttcacca
    27601 ttagcattaa atattcctcc accactcata ccaggatttc caccttgata ttgaacaccg
    27661 taggtgttat tcgcatattc ttgttccatt tctaccgtag catcttttaa gtgcgtatat
    27721 ttcctagctg gatatccatg aacatttagt ttgtcattaa gatttacttt cgaataattt
    27781 ttaactaatt ctacatgttc tctgccagtt gtttcaggta gcttaatcac tgctaaatca
    27841 tagataaatc cttttggata atctttttta ttataaaaat gaatattgtt agcagtaaat
    27901 gttccttttt gtccatcagg agtcacccac tcatatacgt ttttagattt atcacctcta
    27961 aattcgccag tagtattatc agtagaatta ttaatgaaat tatgtgctac tgttaaaagt
    28021 acatttggtg caataaaagt agctgatcct actccagtaa ccttcgacga atctgtaata
    28081 aagttcatat taattaatgc actagatttt ttctgaatac tcatttcttc tggtgtatta
    28141 gtattttcat tatttggttt agtatcttct gcactaggtt gttcgatttt accagtatat
    28201 tctttcagtg cttctacttt ctctggctcg actat
//
LOCUS       DBERCW010000027        26289 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.027, whole genome shotgun sequence.
ACCESSION   DBERCW010000027 DBERCW010000000
VERSION     DBERCW010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.027"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..899
                     /gene="lytB"
                     /locus_tag="ACL72M_001434"
     CDS             <1..899
                     /gene="lytB"
                     /locus_tag="ACL72M_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGS0716550.1"
                     /translation="KNETVDGYQLGSDGKWLGGKTTNENAAYYQVVPVTANVYDSDGE
                     KLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGH
                     RFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAE
                     ELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNN
                     FFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASD
                     PYWGEKIASVMMKINEKLGGKD"
     gene            complement(960..2615)
                     /gene="pavA"
                     /locus_tag="ACL72M_001435"
     CDS             complement(960..2615)
                     /gene="pavA"
                     /locus_tag="ACL72M_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGS0716551.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIGLDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2720..3217
                     /gene="ybeY"
                     /locus_tag="ACL72M_001436"
     CDS             2720..3217
                     /gene="ybeY"
                     /locus_tag="ACL72M_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGS0716552.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHKLNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3198..3593
                     /locus_tag="ACL72M_001437"
     CDS             3198..3593
                     /locus_tag="ACL72M_001437"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS0716553.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3610..4509
                     /gene="era"
                     /locus_tag="ACL72M_001438"
     CDS             3610..4509
                     /gene="era"
                     /locus_tag="ACL72M_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGS0716554.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4558..5382
                     /gene="mutM"
                     /locus_tag="ACL72M_001439"
     CDS             4558..5382
                     /gene="mutM"
                     /locus_tag="ACL72M_001439"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGS0716555.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5382..5987
                     /gene="coaE"
                     /locus_tag="ACL72M_001440"
     CDS             5382..5987
                     /gene="coaE"
                     /locus_tag="ACL72M_001440"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGS0716556.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5974..7173
                     /locus_tag="ACL72M_001441"
     CDS             5974..7173
                     /locus_tag="ACL72M_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HGS0716557.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7173..7322
                     /gene="rpmG"
                     /locus_tag="ACL72M_001442"
     CDS             7173..7322
                     /gene="rpmG"
                     /locus_tag="ACL72M_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0716558.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7362..7595
                     /gene="secG"
                     /locus_tag="ACL72M_001443"
     CDS             7362..7595
                     /gene="secG"
                     /locus_tag="ACL72M_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGS0716559.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7697..10051
                     /gene="rnr"
                     /locus_tag="ACL72M_001444"
     CDS             7697..10051
                     /gene="rnr"
                     /locus_tag="ACL72M_001444"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGS0716560.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNH
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYVDVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10014..10481
                     /gene="smpB"
                     /locus_tag="ACL72M_001445"
     CDS             10014..10481
                     /gene="smpB"
                     /locus_tag="ACL72M_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGS0716561.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10497..11357
                     /gene="tehB"
                     /locus_tag="ACL72M_001446"
     CDS             10497..11357
                     /gene="tehB"
                     /locus_tag="ACL72M_001446"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGS0716562.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11430..12383
                     /gene="coiA"
                     /locus_tag="ACL72M_001447"
     CDS             11430..12383
                     /gene="coiA"
                     /locus_tag="ACL72M_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGS0716563.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12402..14204
                     /gene="pepF"
                     /locus_tag="ACL72M_001448"
     CDS             12402..14204
                     /gene="pepF"
                     /locus_tag="ACL72M_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS0716564.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14206..14919
                     /locus_tag="ACL72M_001449"
     CDS             14206..14919
                     /locus_tag="ACL72M_001449"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGS0716565.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14986..15927
                     /gene="prsA"
                     /locus_tag="ACL72M_001450"
     CDS             14986..15927
                     /gene="prsA"
                     /locus_tag="ACL72M_001450"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGS0716566.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16044..16385)
                     /locus_tag="ACL72M_001451"
                     /pseudo
     CDS             complement(16044..16385)
                     /locus_tag="ACL72M_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16799..16894
                     /locus_tag="ACL72M_001452"
                     /pseudo
     CDS             16799..16894
                     /locus_tag="ACL72M_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(17148..17768)
                     /locus_tag="ACL72M_001453"
     CDS             complement(17148..17768)
                     /locus_tag="ACL72M_001453"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0716567.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(17768..18250)
                     /locus_tag="ACL72M_001454"
     CDS             complement(17768..18250)
                     /locus_tag="ACL72M_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGS0716568.1"
                     /translation="MAKKVKIKKTLAEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18250..19092)
                     /locus_tag="ACL72M_001455"
     CDS             complement(18250..19092)
                     /locus_tag="ACL72M_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGS0716569.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19187..19987)
                     /locus_tag="ACL72M_001456"
     CDS             complement(19187..19987)
                     /locus_tag="ACL72M_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGS0716570.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20131..21510
                     /gene="glmU"
                     /locus_tag="ACL72M_001457"
     CDS             20131..21510
                     /gene="glmU"
                     /locus_tag="ACL72M_001457"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGS0716571.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21520..22065
                     /locus_tag="ACL72M_001458"
     CDS             21520..22065
                     /locus_tag="ACL72M_001458"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0716572.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            22077..22391
                     /gene="macP"
                     /locus_tag="ACL72M_001459"
     CDS             22077..22391
                     /gene="macP"
                     /locus_tag="ACL72M_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGS0716573.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            22408..23100
                     /locus_tag="ACL72M_001460"
     CDS             22408..23100
                     /locus_tag="ACL72M_001460"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGS0716574.1"
                     /translation="MKIGIIAAMPEELAYLVQHLYNVQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            23177..23668
                     /gene="rocS"
                     /locus_tag="ACL72M_001461"
     CDS             23177..23668
                     /gene="rocS"
                     /locus_tag="ACL72M_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGS0716575.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23766..24356
                     /locus_tag="ACL72M_001462"
     CDS             23766..24356
                     /locus_tag="ACL72M_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGS0716576.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            24365..26128
                     /locus_tag="ACL72M_001463"
     CDS             24365..26128
                     /locus_tag="ACL72M_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGS0716577.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASFFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         7992 a         4783 c         5755 g         7759 t
ORIGIN      
        1 cgaaaaatga gacagtagat ggttatcagc ttggaagcga tggtaaatgg cttggaggaa
       61 aaactacaaa tgaaaatgct gcttactatc aagtagtgcc tgttacagcc aatgtttatg
      121 attcagatgg tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg
      181 atagaaaaag tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga
      241 aaacagaaga tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg
      301 atggccaccg tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc
      361 tttctgatat ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatggtt
      421 ttaagcttga gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg
      481 aagaattgga taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg
      541 gcgctacttt taaggaagcc gaagaacatt accatatcaa tgccctttat ctccttgccc
      601 atagtgccct agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct
      661 ttggcattac agcctatgat acgacccctt acctttctgc taagacattt gatgatgtgg
      721 ataagggaat tttaggtgca accaagtgga ttaaggaaaa ttatatcgat aggggaagaa
      781 ctttccttgg aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg
      841 gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa gctaggtggc aaagattagt
      901 actataagtg aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaaat
      961 caggattttt tcatggatgc aatttttttg gagtctggtg tgacgcggag ggtcttttgt
     1021 cctgtgtaag tgacaaagcc gggttttcca ccagttggtt tattgagttt tttgacttca
     1081 atcatatcta cctgcaccag attcgacagg cgcccttgag agaagtaggc agctaactct
     1141 gctgcgtctg tcttgactgc atcagatggg tcaagatttc ctgagatgac aacatggctt
     1201 ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc gggccatttt aaaggtcaat
     1261 tcctcatttt gaagattgtt tcgtccgaca tagatgatgg ttttgccatc gcttgctaga
     1321 tattgttcta gttttttgcg tttctggatt ttctcccgtt gtcttctgcg gataaaacct
     1381 gtttgaatca attcttcacg gatttcagcg atttcttcca gtccagcttg gttgaggacg
     1441 gtttctacac tttccagata gagaatagtg gctttggttt cttcaatcaa atcagtcaag
     1501 tatttgacag cttctttgag tttctgatac cgtttaaaat agcgttgggc attctggttg
     1561 ggagtcagag ccttatcaag cccaatcatg ataggttggt tggtatagta gttgtctagg
     1621 ataacctggt cttggtcgtt aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt
     1681 tgacgaaatt cttcagcgtt gtctgtcgcc agtaattctt tttcctgttt tttgagtttg
     1741 tgtcggtttt tctgaagttc attttcaaca cgacgaatca gttcactggc ctgctgtttg
     1801 acgcggtcgc gctcagcctt atccttatag taggtgtcca acaaatcaga aagatttgca
     1861 aaaggctctc ccacctgatt tgcaaaagga actggactga aggaagtctc agtcaagcat
     1921 ggcttggttt cctgattgaa aaaatttcgg aaagcggaaa gtttttcact aaccagtatc
     1981 ctttccaatt catttgccgt atcgcgtccc agaccttgaa agaggctttg aagatttttt
     2041 gctgttagtt cttgggtttg caggatttca aagagctttt catccttgat agtaaaagga
     2101 ttgagagatt ctgtacttgg cggagcgata taggtcgatc ctggaagtaa ggtgcggtag
     2161 ctattttgtg aaaagccgac gtgtttgata acttcgagga ttttatgact gcttttatcg
     2221 accagtagaa tattactgtg tttccccata atttcgataa tcaaggtagc ctggatatgg
     2281 tctccaatct cgtttttatt ggaaactgtc atttccacaa tacggtcatt ttccacttgc
     2341 tcaatcgact caatcagggc cccctgcaaa tactttctca aaaccatgat aaaggtagaa
     2401 ggttgggctg gattttcaaa agtcgtttgg gtcagctgaa tgcgtccaaa aactggatgg
     2461 gcagaaagga gcaggcgatg gctttggcga ttgctgcgga tttgcaagac caactcttgt
     2521 tcaaaaggct gattgatttt ctggatgcga ccattcacta attcgcttcg caattcctca
     2581 actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc tctccttgtg attgtattcc
     2641 atagtattat atcaaaaagg tagaataaaa tcatggaaat gtggtataat aaagccaagt
     2701 aaagagaaac gagaagcaca tgtatattga aatggtagat gaaactggtc aagtttcaaa
     2761 agaaatgttg caacaaaccc aagaaatttt ggaatttgca gccaaaaaat taggaaaaga
     2821 agacaaggag atggcagtca cttttgtgac caatgagcgt agtcataaac ttaatctgga
     2881 gtaccgtgac accgaccgtc cgacagatgt catcagcctt gagtataaac cagaattgga
     2941 aattgccttt gacgaagagg atttgcttga aaatccagaa ttggcagaga tgatgtctga
     3001 gtttgatgcc tatattgggg aattgttcat ctctatcgat aaggctcatg agcaggccga
     3061 agaatatggt cacagctttg agcgtgagat gggcttcttg gcagtacacg gctttttaca
     3121 tattaacggc tatgatcact atactccgga agaagaagcg gagatgttcg gtttacaaga
     3181 agaaattttg acagcctatg gactcacaag acaataaacg aaaatggaaa aatcgtgacc
     3241 tgatatccag tttagaattt gccatcacag ggatttttac tgctatcaag gaagaacgca
     3301 atatgcgaaa acatgcagtg acggctctag tggtcatcct tgcaggtttt ggttttcagg
     3361 tgtcacgaat cgaatggctc tttctcctat tgagcatttt cttggtggta gcctttgaaa
     3421 ttatcaattc tgctattgaa aatgtggtgg atttggccag tcactatcac ttttccatgc
     3481 tggctaaaaa tgccaaggat atggcggctg gcgcggtatt agtggtttct ctttttgcag
     3541 ccttaacagg cgcattgatt tttctcccac gaatctggga tttattattt taaacagtaa
     3601 gaggaaatta tgacttttaa atcaggcttt gtagccattt taggacgtcc caatgttggg
     3661 aagtcaacct ttttaaatca cgttatgggg caaaagattg ccatcatgag tgacaaggcg
     3721 cagacaacgc gcaataaaat catgggaatt tacacgactg ataaggagca aattgtcttt
     3781 atcgacacac cagggattca caaacctaaa acagctctcg gagatttcat ggttgagtct
     3841 gcctacagta cccttcgcga agtggacact gttcttttca tggtgcctgc tgatgaagcg
     3901 cgtggtaagg gggacgatat gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt
     3961 ttggtggtga ataaaatcga taaggtccat ccagaccagc tcttgtctca gattgatgac
     4021 ttccgtaatc aaatggactt taaggaaatt gttccaatct cagcccttca gggaaataac
     4081 gtgtctcgtc tagtggatat tttgagtgaa aatctggatg aaggtttcca atatttcccg
     4141 tctgatcaaa tcacagacca tccagaacgt ttcttggttt cagaaatggt tcgcgagaaa
     4201 gtcttgcact taactcgtga agagattccg cattctgtag cagtagttgt tgactctatg
     4261 aaacgagacg aagagacaga caaggttcac atccgtgcaa ccatcatggt cgagcgcgat
     4321 agccaaaaag ggattatcat cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg
     4381 gcccgtcgtg atatcgaact catgctagga gacaaggtct tcctagaaac ctgggtcaag
     4441 gtcaagaaaa actggcgcga taaaaagcta gatttggctg actttggcta taatgaaaga
     4501 gaatactaag tagaggtagg ctcatgcctg cttcttgttt ttacagaagg aggacttatg
     4561 cctgaattac ctgaggttga aaccgtttgt cgtggcttag aaaaattgat tataggaaag
     4621 aagatttcga gtatagaaat tcgctacccc aagatgatta agacggattt ggaagagttt
     4681 caaagggaat tgcctagtca gattatcgag tcaatgggac gtcgtggaaa atatttgctt
     4741 ttttatctga cagacaaggt cttgatttcc catttgcgga tggagggcaa gtatttttac
     4801 tatccagacc aaggacctga acgcaagcat gcccatgttt tctttcattt tgaagatggt
     4861 ggcacgcttg tttatgagga tgttcgcaag tttggaacca tggaactctt ggtgcctgac
     4921 cttttagacg cctactttat ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt
     4981 gatttacagg tctttcaatc tgcccttgcc aagtccaaaa agcctatcaa atcccatctc
     5041 ctagaccaga ccttggtagc tggacttggc aatatctatg tggatgaggt tctctggcga
     5101 gctcaggttc atccagctag accttcccag actttgacag cagaagaagc gactgccatt
     5161 catgaccaga ccattgctgt tttgggccag gctgttgaaa aaggtggctc caccattcgg
     5221 acttatacca atgcctttgg ggaagatgga agcatgcagg actttcatca ggtctatgat
     5281 aagactggtc aagaatgtgt acgctgtggt accatcattg agaaaattca actaggtgga
     5341 cgtggaaccc acttttgtcc aaactgtcaa aggagggact gatgggaaaa atcatcggaa
     5401 tcactggggg aattgcctca ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct
     5461 ttcaagcagt ggatgccgac gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt
     5521 ttgaggctct agtacagcac tttgggcaag aaatcattct tgaaaacgga gaactcaatc
     5581 gccctctcct agctagtctc atcttttcaa atcctgaaga gcaaaaatgg tctaatcaaa
     5641 ttcaagggga gattatccgt gaggaactgg ctactttgag agaacagttg gctcagacag
     5701 aagagatttt cttcatggat attcccctac tttttgagca ggactacagc gattggtttg
     5761 ctgagacttg gttggtctat gtggaccgag atgcccaagt agaacgctta atgaaaaggg
     5821 accagttgtc caaagatgaa gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa
     5881 agaaagattt ggccagccag gttcttgata ataatggcaa tcagaaccag cttcttaatc
     5941 aagtgcatat ccttcttgag ggaggtaggc aagatgacag agattaactg gaaggataat
     6001 ctgcgtattg cctggtttgg taattttctg acaggagcca gtatttcttt ggttgtacct
     6061 tttatgccca tcttcgtgga aaatctaggt gtagggagtc agcaagtcgc tttttatgca
     6121 ggcttagcaa tttctgtctc tgctatttcc gcggcgctct tttctcctat ttggggtatt
     6181 cttgctgaca aatacggccg aaaacccatg atgattcggg caggtcttgc tatgactatc
     6241 actatgggag gcttggcctt tgtcccaaat atctattggt taatctttct tcgtttacta
     6301 aacggtgtat ttgcaggttt tgttcctaat gcaacggcac tgatagccag tcaggttcca
     6361 aaggagaaat caggctctgc cttaggtact ttgtctacag gcgtagttgc aggtactcta
     6421 actggtccct ttattggtgg ctttattgca gaattatttg gcattcgtac agttttctta
     6481 ctggttggta gttttctatt tttagctgct attttgacta tttgctttat caaggaagat
     6541 tttcaaccag tagccaagga aaaggctatt ccaacaaagg aattatttac ctcggttaaa
     6601 tatccctatc ttttgctcaa tctcttttta accagttttg tcatccaatt ttcagctcaa
     6661 tcgatcggcc ctattttggc tctttatgta cgcgacttag ggcagacaga gaatcttctt
     6721 tttgtctctg gtttgattgt gtccagtatg ggcttttcca gtatgatgag tgcaggagtc
     6781 atgggcaagc taggtgacaa ggtgggcaat catcgtctct tggttgtcgc ccagttttat
     6841 tcagtcatca tctatctcct ctgtgccaat gcctctagcc cccttcaact aggactctat
     6901 cgtttcctct ttggcttggg aaccggtgcc ttgattcccg gggttaatgc cctactcagc
     6961 aaaatgactc ccaaagccgg catttcgagg gtctttgcct ttaatcaggt attcttttat
     7021 ctgggaggtg ttgttggtcc catggcaggt tctgcagtag caggtcaatt tggctaccat
     7081 gctgtctttt atgcgacaag cctttgtgtt gcctttagtt gtctctttaa cctgattcaa
     7141 tttcgaacat tattaaaagt aaaggaaatc tagtgcgagt aaaaattaat ctcaaatgct
     7201 cctcttgtga cagtatcaat tacctaacca gtaaaaattc aaaaacccat ccagacaaga
     7261 ttgaggtttt aaagtattgt cccaaggaaa gaaaagtaac cctacatctt gaatctaagt
     7321 agattttatg gtaaaataat agggatttta aggagtttga tatgtataac ctattattaa
     7381 ccattttatt agtattatct gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa
     7441 accaatccag caatgtattt gatgccagtt caggtgattt gtttgaacgc agtaaagctc
     7501 gcggttttga agctgtaatg cagcgtttga cagggatttt agtctttttc tggctagcca
     7561 ttgccttagc attgacggta ttatcaagta gataagaaaa taatgggcag gactaggtct
     7621 ttgcctcttt ttatttttaa aggatgtttg agaaggtttt acagtaaaag aaaattaaaa
     7681 aatctagaaa gaaaatatga aagatagaat aaaagaatat ttacaagaca agggaaaggt
     7741 gactgttaat gatttggctc aggctttggg aaaagacagt tccaaggatt ttcgtgagtt
     7801 gattaaaacc ttgtccttaa tggaaagaaa gcaccagatt cgctttgaag aagatggtag
     7861 tctgacatta gaaattaaga aaaaacatga gattaccctc aaggggattt ttcatgccca
     7921 taaaaatggc tttggctttg ttagtctgga aggcgaggag gacgaccttt ttgtagggaa
     7981 aaatgatgtc aactatgcta ttgatggtga taccgtcgag gtagtgatta agaaagtcgc
     8041 tgaccgcaat aagggaacag cagcagaagc caaaattatt gatatcctag aacacagttt
     8101 gacaacagtt gtcgggcaaa tcgttctgga tcaggaaaag cctaagtatg ctggctatat
     8161 tcgttcaaaa aatcataaaa tcagtcaacc gatttatgtt aagaaaccag ccctaaaatt
     8221 agaaggaaca gaagttctca aagtctttat cgataaatac ccaagcaaga aacatgattt
     8281 ctttgtcgct agtgtactcg atgtagtggg acactcaacg gatgtcggaa ttgatgttct
     8341 tgaggtcttg gaatcaatgg acattgtatc tgagtttcca gaagctgttg tcaaggaagc
     8401 agaaagtgtg cctgatgctc cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga
     8461 tgaaattacc tttaccattg acggtgcgga tgccaaggac ttagacgatg cagtgcatat
     8521 caaggctctg aaaaatggca atctggagct tggggttcac atcgcagatg tttcctatta
     8581 tgtgaccgag gggtctgccc ttgacaagga agcccttaac cgtgcgactt ctgtttacgt
     8641 gacagaccga gtggtgccaa tgcttccaga acgactatca aatggcatct gctctctcaa
     8701 tccccaagtt gaccgcctga cccagtctgc tattatggag attgataaac atggtcgtgt
     8761 ggtcaactat accattacac aaacagttat caagaccagt tttcgtatga cctatagcga
     8821 tgtcaatgat atcctagctg gcgatgaaga aaagagaaaa gaatatcata aaattgtacc
     8881 aagtatcgaa ctcatggcca agcttcatga aactttagaa aacatgcgtg tgaaacgtgg
     8941 agctctcaat tttgatacca atgaagcgaa gattttagtg gataaacaag gtaagcctgt
     9001 tgatatcgtt cttcggcagc gtggcattgc cgagcggatg attgagtctt ttatgttgat
     9061 ggctaatgaa acagttgccg aacatttcag caagttggat ttgcctttta tctatcgaat
     9121 tcacgaggag cctaaggctg aaaaggttca gaagtttatt gattatgctt cgagttttgg
     9181 cttgcgcatt tatgggactg ccagtgagat tagtcaggag gcacttcaag acatcatgcg
     9241 tgctgttgag ggagaacctt atgtagatgt attgtccatg atgcttcttc gctctatgca
     9301 gcaggctcgt tattcggagc acaatcacgg ccactatgga ctagctgctg actattatac
     9361 tcactttacc agtccaattc gtcgttatcc agaccttctt gttcaccgta tgattcggga
     9421 ttacggctgt tctaaggaaa tagcagagca ttttgaacaa gtgattccag agattgcgac
     9481 ccagtcttcc aaccgtgaac gtcgtgccat agaagctgag cgtgaagtcg aagccatgaa
     9541 aaaggctgag tatatggaag aatacgtggg tgaagagtat gatgcagttg tatcaagtat
     9601 tgtcaaattc ggtctctttg tcgaattgcc aaacacagtt gaaggcttga ttcacatcac
     9661 taatctacct gaattttatc atttcaatga gcgtgatttg actcttcgtg gagaaaaatc
     9721 aggtatcact ttccgagtgg gtcagcagat ccgtatccgt gttgaaagag cggataaaat
     9781 gactggagag attgattttt cattcgtacc tagtgagttt gatgtgattg aaaaaggctt
     9841 gaaacagtct agtcgtagtg gcagagggcg tggttcaaat cgtcgttcgg ataagaagga
     9901 agacaagaga aaatcaggac gctcaaatga taagcgtaag cattcacaaa aagacaagaa
     9961 gaaaaaagga aagaaacctt tttacaagga agtagctaag aaaggagcca agcatggcaa
    10021 agggcgaggg aaaggtcgtc gcacaaaata aaaaggcacg ccacgactat acaatcgtag
    10081 atacgctaga ggcagggatg gtcctgactg gaactgaaat caagagtgta cgagctgctc
    10141 gaattaatct caaggatggc tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg
    10201 ttcatatcgc gccttacgaa gagggcaata tctggaacca ggaaccagaa cgtcgtcgta
    10261 aactcctgct ccataaaaag caaattcaaa aattggaaca agagaccaaa gggacaggaa
    10321 tgaccttagt tccccttaag gtctatataa aagatggcta cgctaagctt cttttaggac
    10381 ttgccaaagg gaagcatgac tatgacaaac gggagtctat caaacgtcgt gagcaaaatc
    10441 gagatatcgc gcgtgtgatg aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg
    10501 aaaaattagt tgcctataaa cgcatgcctt tgtggaataa acaaacaatg cctgaagctg
    10561 ttcagcaaaa gcacaataca aaagttggga cttgggggaa aattactgtc ttgaagggag
    10621 ctctcaagtt tattgaattg acagaagaag gggaagttct agctgaacac ctctttgaag
    10681 caggggcaga caatccaatg gcccaacctc aagcctggca ccgagtggaa gctgccacag
    10741 atgatgtgga atggtacttg gaattttatt gtaaacctga ggattatttt gctaaaaaat
    10801 acaataccaa tcctgttcat tcagaggtcc tagaggccat gcagacagtg aaacaaggga
    10861 aagctttgga tttgggttgt ggtcaggggc gtaattctct ttttctagcc cagcaagatt
    10921 ttgatgtgac ggctgtagat caaaatggac tagctcttga aatcttgcaa agcattgtgg
    10981 agcaggaaga tttggacatg cctgttggcc tttacgatat caattcagct agcattgaac
    11041 aagaatatga ttttatcgtt tcaacagttg ttctcatgtt tctacaagcg gaccgcattc
    11101 cagctattat tcaaaatatg caggagaaaa ccagtgttgg cggttacaac cttatcgttt
    11161 gtgccatgga cacggaggat tatccttgct cggttaactt cccattcacc tttaaagaag
    11221 gagaactggc agactattac aaggattggg aattggttaa gtacaatgaa aatccaggcc
    11281 atttgcaccg tcgcgatgag aatggcaatc gtattcaact acgctttgcg accttactag
    11341 ctaagaaaat caagtaaaca cacatgaaga ttaggaattt tcctgatctt ttttcttttt
    11401 tacgaatgat atagaaaagg agggaattca tgtttgttgc gagagatgct aggggagaat
    11461 tggtaaatgt gttagaggat aaacttgaga agcaagcata cacctgccca gcttgtggag
    11521 gccagctcca tttgcgtcaa ggaccaagtg tacggacgca ttttgcccat aaatccttaa
    11581 aagactgtga ttttttcttt gaaaatgaaa gtccagaaca cctggccaat aaggaatccc
    11641 tctatcactg gttgaaaaaa gagacaaagg ttcaattaga gtacccgctt tcagaactta
    11701 aacagattgc ggatgtattt gtaaatggca atctagctct agaagttcag tgtagtccct
    11761 tgcctcagaa agtccttaaa gagcgaagtg agggctatcg tagtcagggt taccaagtac
    11821 tgtggttgct gggtcaaaaa ctgtggctca aggagcgttt gactcgtcta cagcaaggtt
    11881 ttctttattt cagtcaaaac atgggctttt atgtttggga attagacaag gaaaaacaag
    11941 ttttaagact caaatacctg atttaccagg atctccgcgg taaactccat tatcaaatca
    12001 aggaattttc ctatggtcaa ggtagtttat tggaaatatt gcgtcttccc tataagagac
    12061 aaaaaatatc tcattttaca gtttctgagg acaaggacat ctgtcgctat atccggcaac
    12121 aactttatta tcaaaatctc ttttggatga aagaacaagc agaagcctat caaaagggag
    12181 aaaatatcct gacttatgga ctgaaagaat ggtatccaca aattcgacca atagtgggca
    12241 aatttttcca gattgaacaa gacttgacta gctattatca gcacttttat acctattacc
    12301 aaaaaaatcc tcaaaatgat tggcaaaagc tttatccacc agccttttat cagcaatatt
    12361 tcttgaaaaa tatggtagaa tagaaaggat ggaggaatct aatggtatta caaagaaatg
    12421 aaataaatga aaaagataca tgggatctat caacgatcta cccaactgac caggcttggg
    12481 aagaagcctt aaaagattta acagaacaat tggagacagt agcccagtat gaaggccatc
    12541 tcttggatag tgcggataac ctactagaaa tcactgaatt ttctcttgaa atggaacgcc
    12601 agatagagaa gctttacgtt tatgctcata tgaagaatga ccaggataca cgtgaagcta
    12661 agtatcaaga gtactatgcc aaggccatga cactctacag ccagttagac caagcctttt
    12721 cattctatga gcctgaattt atggagatta gcgaaaagca gtatgctgac tttttagaag
    12781 ctcaaccaaa gctgcaggtt tatcaacact attttgacaa gctcttgcaa ggcaaggatc
    12841 acgttctttc acaacgtgaa gaagaattat tggctggagc tggagaaatc tttggttcag
    12901 caagtgaaac cttcgctatc ttggacaatg cggatattgt gttcccttat gtcctagacg
    12961 atgatggtaa agaagttcag ctatctcatg ggacttacac acgtttgatg gagtctaaaa
    13021 aacgtgaggt tcgccgtggt gcctatcaag ctctttatgc tacttacgaa caattccaac
    13081 acacctatgc caaaaccttg caaaccaatg ttaaggtgca aaattaccgt gctaaagttc
    13141 gtaactacaa gagtgctcgt catgcagccc tcgcagcgaa ttttgttcca gaaagtgttt
    13201 atgacaattt ggtagcagca gttcgcaagc atttgccact cttacatcgc tatcttgagc
    13261 ttcgttcaaa aatcttgggg atttcagatc tcaagatgta cgatgtctac acaccgcttt
    13321 catctgttga atacagtttt acctaccaag aagccttgaa aaaagcagaa gatgctttgg
    13381 cagtcttggg tgaggattac ttgagccgtg ttaaacgtgc cttcagcgag cgttggattg
    13441 atgtttacga aaatcaaggc aagcgttcag gtgcctactc tggtggttct tacgatacca
    13501 atgcctttat gcttctcaac tggcaggaca atctggacaa tctctttact cttgttcatg
    13561 aaacaggtca cagtatgcat tcaagctata ctcgtgaaac tcagccttat gtttacgggg
    13621 attactctat ctttttggct gagattgcct caactaccaa tgaaaatatc ttgacggaga
    13681 aattattgga agaagtggaa gacgacgcaa cacgctttgc tattctcaat aacttcctag
    13741 atggtttccg tggaacagtt ttccgccaaa ctcaatttgc tgagtttgaa cacgccattc
    13801 accaagcaga tcaaaatggg gaggtcttga caagcgattt cctaaataaa ctctacgcag
    13861 acttgaacca agagtattat ggtttgagta aggaagacaa tcctgaaatc caatacgagt
    13921 gggctcgcat tccacacttc tactataact actatgtata tcaatattca actggctttg
    13981 cggccgcctc agccttggct gaaaaaattg tccatggtag tcaagaagac cgtgaccgct
    14041 atatcgacta cctcaaggca ggtaagtcgg actatccact taatgtcatg agaaaagctg
    14101 gtgttgatat ggagaaggaa gactacctca acgatgcctt tgcagtcttt gaacgccgtt
    14161 taaatgagtt tgaagccctt gttgaaaaat taggattggc ataaaatggt tgaatcgtat
    14221 agtaagaatg ctaaccataa catgcgtcgt cctgtcgtca aagaagaaat tgtagacttg
    14281 atgcgtcagc gtcaaaagca ggtcacaggt ttcttgaaag aattggaaga ctttgcccgc
    14341 aaggaaaata ttcctattat tccccatgaa acggttgctt atttccgttt tcttatggaa
    14401 accatgcagc ctaaaaatat tctggaaatt gggacggcta tcggtttttc agctctcttg
    14461 atggctgaac atgcgccaaa tgctaagatt acaactattg atcgtaatcc agaaatgatt
    14521 ggttttgcca aggaaaattt tgcccagttt gacagtcgca agcaaatcac tctcctagag
    14581 ggagatgcgg tggatgtctt atctacactg acagagtctt atgatttcgt atttatggat
    14641 tctgccaagt ctaaatacat cgtctttctg ccagaaatcc tcaaacattt ggaagttggt
    14701 ggtgtggttg tcttggatga tatttttcaa ggtggtgatg ttgccaagga tattatggaa
    14761 gtccgtcgtg gtcagcgaac catttatcga ggccttcaaa aattatttga tgcaacctta
    14821 gacaatccag aactcaccgc aacattagtg cctttaggag atggtattct catgcttcgt
    14881 aaaaatgtag cagatgttca actgtctgaa agcgaatgat tttcagaaaa atttaagaaa
    14941 aaatagtaaa atagatagag taacacttat ctcaaaggag tagacatgaa gaaaaaatta
    15001 ttggcaggtg ccatcacact attatcagta gcaactttag cagcttgttc gaaagggtca
    15061 gaaggagcag accttatcag catgaaaggg gatgtcatca cagaacatca attttatgag
    15121 caagtgaaaa acaacccttc agcccaacaa gtcttgttaa atatgaccat ccaaaaagtt
    15181 tttgaaaaac aatatggctc agagcttgat gataaagagg ttgatgatac tattgccgaa
    15241 gaaaaaaaac aatatggcga aaactaccaa cgtgtcttgt cacaagcagg tatgactctt
    15301 gaaacacgta aagctcaaat tcgtacaagt aaattagttg agttggcagt taagaaggta
    15361 gcagaagctg aattgacaga tgaagcctat aagaaagcct ttgatgagta cactccagat
    15421 gtaacggctc aaatcatccg tcttaataat gaagataagg ccaaagaagt tctcgaaaaa
    15481 gccaaggcag aaggtgctga ttttgctcaa ttagccaaag ataattcaac tgatgaaaaa
    15541 acaaaagaaa atggtggaga aattaccttt gattctgctt caacagaagt acctgagcaa
    15601 gtcaaaaaag ccgctttcgc tttagatgtg gatggtgttt ctgatgtgat tacagcaact
    15661 ggcacacaag cctacagtag ccaatattac attgtaaaac tcactaagaa aacagaaaaa
    15721 tcatctaata ttgatgacta caaagaaaaa ttaaaaactg ttatcttgac tcaaaaacaa
    15781 aatgattcaa catttgttca aagcattatc ggaaaagaat tgcaagcagc caatatcaag
    15841 gttaaggacc aagccttcca aaatatcttt acccaatata tcggtggtgg agattcaagc
    15901 tcaagcagta gtacatcaaa cgaatagtcc aaatcaatga gtcagggaaa aaactctact
    15961 tcaggaaaaa atgaagcaaa cattcccaca ataaaacgcg tagtacaagg tttgtactga
    16021 cccccaaaag ttagacaaat aatttatccg aaggatttag ttctgtattg cacagggcta
    16081 agtcctttta gttttacctt aattctcttg ttgttgtaat aatcaatata gtatataatg
    16141 gcttgttcca attgattaag tgatttaaat gttttctcat agccataaaa catttcggat
    16201 tttaaaatac caaagaaaga ttccatccta ccgttgtctt ggctgtttcc cttgcgtgac
    16261 atagatgctt gaattccctt actctctagg aaccgatgat aagaatcgtg ttggtattgc
    16321 cagtcttggt cactatggag aatcgtattc tcgtagtgct tctctttgaa tgcctgttcc
    16381 aacattaacg atcaatcaat ttaatcatgt acctaatatt agaattgttt atctcaaatt
    16441 tatttgaaag cttctctaag ctatatcctt gttttctaag ttcatagatc tgaactttat
    16501 catcataagt taatttcata ataaaaacac tccaaaagtt agattttttc tgtctaactt
    16561 ttggggtgca gttcatttaa cacctgataa tatgcgtttt ttttatttta aagacttttt
    16621 gaccagcctc attttttaac ttgatactca gtgaaaagca aagattaaac taggaagcta
    16681 gctgtaggct gctcaaagaa cagctttgag gttgcagata aaacttgtga ggtaaccaac
    16741 atatataatg tgaagctgac gtggtttgaa tagattttag aagggtatga gtctggaagt
    16801 tttaatggat aatgcaagat tccatagaat gggtaagcta gagttcttat gtgaagagtt
    16861 tgggcataaa cttttacctt ttcctcccta ctcatcttag tatagaaaag tgaatctaaa
    16921 atagtacata actgcttcta aaacattctt ataaattgat ttaaattctc aaatcatatt
    16981 attcagttct tatttcattt tgctctacaa tcctgttgag aagacacgtg ttcatatcaa
    17041 aaaaggtatt ggcaagttgc aatacctttt tacgaggctc ttttatctta tttttgtttc
    17101 aactgactat atctcctatg gttctagttc agaaggctag gctataatta tgattgataa
    17161 gaagtatcat tccaagtatt gagagtgaat gtttcaaaat catgggtttc tataatggtc
    17221 aggctggcat ttgctagacc gccatcttta cgaagaagtg gttctttata gcctaggaga
    17281 gtacgaagac tggcagtaag attggcgccg tgtccgacaa ttagaatacg ttcagctgga
    17341 ctatctttta atgatttgat aaattggatg gtccgttgag ttgtactata gagggattcg
    17401 gctccgaaca ttcgagtgtc aaattgagca agatttgaac gaaaagcctg gatttgttgc
    17461 gggtaaatag cttccaaggt tgcaattttc aaaccttcta acttcccaag ttgccattca
    17521 cggagattag gaacgatttc taaagaacag ggggtataga gttgactttg gataatctca
    17581 gcagatttga ccgctcgagg taaatcactt gaataaatct gatcaaaagg aatttccttg
    17641 agatactgac caagtcgttt tagggtttca atggattcag gaagaagagg agaatcacca
    17701 ctagcacctt gaaaacgacc ttcttggttc cagagggtac gaccgtggcg gacaaagtag
    17761 agtttcatta cttgatgtcc tccaaaatat ctacaaagtc tgcctttaca aagctagcca
    17821 agtcttgtgg cgcgacgata atgctgtgtc cgacttcgcc tgcagagaca atcatttgat
    17881 ccaaatctag agcaatttta tcgataaaaa tgggataatt gtgtttctga cgaattccga
    17941 caggattatt ggctccatga atgtaaccag ttgttttttc taagtccttt tgtggaatca
    18001 tgctcacttt tttattgcca gaaattttag ctagtttctt ttcagacaag tgctgagtga
    18061 tagggacaat tccgataatc ggtccggtct tgtctcccaa aagcgccaag gttttgaaaa
    18121 tctgatctcg ttcataacct tgaggaagct ctccttctag ggcattgatt tgaatcccct
    18181 gatgagggat agctgcttta gataggattt gttccgccaa tgtttttttg attttaactt
    18241 tttttgccat tatttatatt tatcctccaa ttgactcatc caaataccaa gccagattcc
    18301 cagcgcaaag aagaaggcga tgatgacata accgacaagt gaaagtcctg tgtattggat
    18361 actttcagcg tttcctgcat ttggaattaa gatcaaaagg gtacttgata ggacgatacc
    18421 gatgatgaaa tgatagacac gtgagtggta gttgtttaag gcataatcca tcaattttga
    18481 aaaaacgatg agagttgcac ctgcaccaat tccaatcgga aagaaggttc ccaagaaatc
    18541 aaaagtttta aaaccagtca acataggagc atagagtccc aaaatcaaaa gtaaatttga
    18601 tgggctgagg ccaggaacca agacgccaag ggccaatagt gcgcctgcta ggacgaagtt
    18661 aagaaagctg gcgcttaagg ttccaacgac aaaatttaag gcatagagtc ctaatccaga
    18721 aatgataaag gttgtccata accaagctaa atcaatcttg tctcggtcag attctcgagt
    18781 tgattctttg aggaggctag gaactgtacc gataatagct cccgcaaagc tccataatac
    18841 aaaaacctga taattttcaa gcaggtattc aatcgggtag gaaaataagc cgattcccag
    18901 aagcataccg atggcaactg gaataaagta caaaacattt tctttaaagt ctttaaaggg
    18961 atgggccaga aagccaatca ttcgttcata gattcctaag attgctgcta gaacccctcc
    19021 ggaaattccc ggtaggataa atccaagagc aattacaatc cctttaataa cgcgtgctaa
    19081 ccatgagagc atatatttcc tccaactatt tctatttcaa aaaatcctta ctatattgta
    19141 tcacaatcag acacaaaaag aaaaagcaaa tgataaacaa atgcttttaa ggttttaaaa
    19201 aaagttttcg aaaggtttct tctttatttt ttaagggaga gataacgttg atatctaaat
    19261 cgtggtcaaa gccggcaatt tttcctttag atgtgtattg gtgaatatca taatctaaat
    19321 cagttttagg actgctctcc aaaaatcctg agtctgagcc gtaggacgga atccaaacag
    19381 aggtaaactt gcctgtatca atactgtgtt cttccatgaa gtagacacca acgtagatgc
    19441 cgatgttttt agcacctagt gatgctagtt ttgctcgaaa gttttcgaca ccttcgttca
    19501 tattagacat ggttttgtct tccacgtcaa gccaatagta actagggctg taaggagagg
    19561 cagcattgta gaaaacttcg gcagcctttt ccatttcttg gacacttttt ccagctacat
    19621 aagcgtagac agcaactggg acattccgct tttgaagttc agtgatatga ctcttatagg
    19681 ccttgtctat tccattgata aatgaagcat cattttcttt tgtcgtttga gcaccactgt
    19741 gaacacgaac aatagcacct gaaatatttt gtgagagggc atcgtagttg atttcttcag
    19801 gacgctgcca gccagagagg tcaataatcg gtttgtctaa gtgtttcaaa gcctgtgctt
    19861 caatctgtgc tatattggat tttgttttaa acgattggtt gtcattaagt gggcgattga
    19921 tgattaaaat gaacatcata atccccaaaa aactaaataa aataagtgga tgaatttgtt
    19981 ttctcatatc ttataattct accctaaaaa tcaaaaaaaa tcaaaaaaat gggttaagga
    20041 agagacttta gagcattttt tcattcaaga gtgcggaatg atttgaaata tggtataata
    20101 aaagggaatt tctacagaaa agagaagatt atgtcaaatt ttgccattat tttagcagcg
    20161 ggtaaaggga ctcgcatgaa atctgatttg ccaaaagttt tgcacaaggt tgcgggtatt
    20221 tctatgttgg aacatgtttt ccgtagtgtg ggagctatcc aacctgaaaa gacagtaaca
    20281 gttgtaggac acaaggcaga attggttgag gaggtcttgg ctggacagac agaatttgtg
    20341 actcaatctg aacagttggg aactggtcat gcagttatga tgacagaacc tatcttagaa
    20401 ggtttgtcag gacacacctt ggtcattgca ggagatactc ctttaatcac tggtgaaagc
    20461 ttgaaaaact tgattgattt ccatatcaat cataaaaatg tggccactat cttgactgct
    20521 gaaacggata atccttttgg ctatggacga attgttcgta atgacaatgc tgaggttctt
    20581 cgtattgttg agcagaagga tgctacagat tttgaaaagc aaatcaagga aatcaacact
    20641 ggaacatacg tctttgacaa cgagcgtttg tttgaggctt tgaaaaatat caataccaat
    20701 aacgctcaag gcgaatacta tattacagac gtcattggta ttttccgtga aactggtgaa
    20761 aaagttggcg cttatacttt gaaagatttt gatgaaagtc ttggggtaaa tgaccgtgtg
    20821 gcgcttgcga cagctgagtc agttatgcgt cgtcgcatca atcataaaca tatggtcaac
    20881 ggtgttagct ttgtcaatcc agaagcaact tatatcgata ttgatgttga gattgctccg
    20941 gaagttcaaa tcgaagccaa tgttaccttg aaagggcaaa cgaaaattgg tgctgagact
    21001 gttttgacaa acggtactta tgtagtggac agcactatcg gagcaggagc ggtcattacc
    21061 aattctatga ttgaggaaag tagtgttgca gacggtgtga cagtcggtcc ttatgctcac
    21121 attcgtccaa attcaagtct gggtgcccaa gttcatattg gtaactttgt tgaggtgaaa
    21181 ggatcttcaa tcggtgagaa taccaaggct ggtcatttga cttatatcgg aaactgtgaa
    21241 gtgggaagca acgttaattt cggtgctgga actattacag tcaattatga cggcaaaaac
    21301 aaatacaaga cagtcattgg agacaatgtc tttgttggtt caaattcaac cattattgca
    21361 ccagtagaac ttggtgacaa ttccctcgtt ggtgctggtt caactattac taaagacgtg
    21421 ccagcagatg ctattgctat tggtcgcggt cgtcagatca ataaagacga atatgcaaca
    21481 cgtcttcctc atcatcctaa gaaccagtag gagcctatca tggagtttga agaaaaaacg
    21541 cttagccgaa aagaaatcta tcaaggacca atatttaaac tggtccaaga tcaggttgaa
    21601 ttaccagaag gcaagggaac tgcccaacgg gatttgattt tccacaatgg ggctgtctgt
    21661 gttttagcag taacggatga acaaaaactg atcttggtca agcagtaccg caaagctatc
    21721 gaggctgtct cttacgaaat tccagccgga aaattggaag taggagaaaa cacagcccct
    21781 gtggcagctg cccttcgtga attagaggaa gaaacagcct atacagggaa attagaactc
    21841 ttgtacgatt tttattcagc tattggcttt tgtaatgaga agttaaaact atatttagca
    21901 agcgatttga caaaagtgga aaatccgcgt ccgcaggatg aggatgaaac cttggaagtc
    21961 cttgaagtga gcttagaaga agcgaaagaa ttaatccaat caggtcatat ttgtgatgcc
    22021 aagacaatta tggctgttca gtattgggag ttgcagaaaa aatagaggag gtcagtatgg
    22081 gtaaatcttt attaacggat gaaatgattg aaagagctaa tagaggcgaa aaaatttcag
    22141 gtcctccttt gctagatgat aatgaggaga ctaagatttt accaacctct tcttcccgtt
    22201 ttggttatgc caatcctaag aatcatggtt ttagccagga aaccttgaag attcaggtcg
    22261 aaccatctat tcataaaagc cgtcgcattg aaaataccaa gagaaatgtc ttcaattcta
    22321 agttgaataa aatcttattc gcggtcatct ttctcttgat tttgcttgtt ttagcaatga
    22381 aacttttgta atagaaaagg aattgaaatg aaaataggaa ttattgctgc tatgccagaa
    22441 gaactggctt atctggtcca gcatttatat aatgtccagg agcaagttgt tttggggaat
    22501 acctatcata caggaaccat tgcttctcat gaagtcgttc ttgtagaaag tggaattggt
    22561 aaggtcatgt ctgctatgag tgtggcgatt ttggctgatc atttccaggt ggatgccctt
    22621 attaatacgg gttcagctgg ggcagtagca gaaggtatcg ctgttgggga tgtcgtgatt
    22681 gctgacaaat tagcctatca tgacgtggat gtcacagctt ttggctatgc ttatggacaa
    22741 atggcgcaac aaccgcttta tttcgaatca gacaaaacct ttgttgctca aatccaagag
    22801 agtttatctc aattggacca aaactggcat cttggtttga ttgctacagg agatagtttt
    22861 gttgcaggaa atgacaagat agaagcgatt aagtcccatt tcccagaagt tttagccgtg
    22921 gagatggagg gggcagctat tgctcaagca gcgcataccc tcaatctccc agtcttagtc
    22981 atccgagcta tgagtgacaa tgccaaccat gaagcaaaca tcttttttga tgagtttatt
    23041 atcgaagctg gacgtcgctc tgcccaagtc ttgttggcct ttttgaaggc tttagattaa
    23101 gcggaaattt gacagttttt ctagcttatg ataagattta agtaaagaaa agctagaaaa
    23161 cgtttcagag gatattatga gtattgaaat gaccgtcagt gagattgcag aggtcttagg
    23221 attatctcgc caagcaatca ataaccgtgt caaagaatta ccagaagaag acacagataa
    23281 aaatgacaaa ggggtaacag ttgttaccag aagtggcttg attaagctag aagaaatcta
    23341 taaaaaaacg atttttgaag atgaacctgt cagtgaagat gtcaaacaac gtgaactgat
    23401 ggagattcta gtggatgaga agaatgcaga aattcttcgt ctttatgaac aattaaaagc
    23461 caaggatcgt cagttatcag aaaaagacga gcagatgcgt atcaaagacc gtcagattgc
    23521 tgagaaagac aaacaattag atcagcaaca acaattgacc cttcaagcca tgaaggatca
    23581 agaaaatctt aagctagagc tggaccaagc aaaagaagaa gtccaatcca ctaaaaaagg
    23641 cttttttgct cgtttatttg gaggataatc aaggagctgt ttaggttaaa tgctaacctg
    23701 atggcttctt ttgtttgtga atagtatagt tgattagaac agagacagta gaggagaggt
    23761 acagaatgga acgattagaa gattacattg cttttgattt agaatttaat cagcacgaag
    23821 gacaaacaca cttgattcaa gtatcggcag tgcgttttag agatggtcgg gaaatcgatg
    23881 cctatgattc ctatgttcat accagcgtcc ctctaaaaag ctttatcaat ggtttgaccg
    23941 ggattacagc tgagacctta aaagatgctc ctccagttga gaaagtctta gaagaattcc
    24001 aagagtttgt gggttctttg ctgatgatag gctacaatgc tgctaaaagt gatttaccta
    24061 ttttagcaga gcatggttta gactatagcc aacagtacaa ggtggatttg tatgatgaag
    24121 cttttgaacg tcggagttca gatttacatg gtattgccaa tctcaaattg caaactgttg
    24181 cctcatttct tggatttcaa ggtcagtctc ataatagttt agaggatgct cggatgacgg
    24241 cgcgtgttta cgaatccttc ttagagtcgg atcaagctag ggaattgtta gagacagaaa
    24301 gtagcttatc aaacaatcct tttggtggct tggacttgtc tcaattattt gactaggagt
    24361 gcctatgaaa cctgaaaaac ctaaaaaatt gggtcttaaa cagatttacc tcaatcttga
    24421 taaaatcctc tttctatttt tcttgatttt tatgatagtg gagtatttgt gggtaccatt
    24481 caattcatgg ttggctagct tcttattaga tcagacaggt tatcttttta tttcctataa
    24541 caatgtctta gccatcctta ctcattctcc attgattagt ctagcttttt tagccttgat
    24601 tgtaattaac tttctggttg cttattttca aataggactc ctctttattg gtgctcgtca
    24661 tctcctctat aatgaaaagc gaaggctaat tgagtatatc cgcaaggttt tccatgaaag
    24721 ttttgaattt atgaaaaagc taactggcgc taaagccttg tttatctttt tctatatagc
    24781 tatgctgttt ccttttatac ggaaaatgct gaagatttat tatcttaata aaatcgtcat
    24841 tccagagttt atccaagctt atttagaaga taaatattgg atgtggtggc tgagcatcct
    24901 acttctatct cttatctttc tctatgtctc tgtcagattg atgtttgccc ttccgaagat
    24961 tgtatatgat cagctgactg ttcgagaagc agtgatgttt agcttggaga aaaccaagaa
    25021 gagagttact ttttatgctt ggaatttatt ttacatcttg ctcaaagcac atttattatt
    25081 ttatcttcct ttgattcctt tattattggc tcaaactttg gtagatgata tcactcagag
    25141 agagtctctg attcttggta ttttgaattt tgtcgtgatt aaaaatctct attatatggc
    25201 tctgacttat tttttggtta aatttgtttc atttttgaca ggaaaggagc tggatatgct
    25261 tcctaggaga gaaaaagatc acatcgtgcg atggggtgtc atgacttgtg ccagtttttt
    25321 ctttgcctta gaaggttata tttatctgga ggctcccatg gttcatctac ctcaacttat
    25381 ttctcaccga ggggtttcca atgcaaatgg gattcaaaat acagtagagt ccttggaaac
    25441 tacagcacaa ctcaaaccag acttggtgga gacggacgtg caggaaacaa aagatgggca
    25501 gtttgtcatg atgcatgatg ctaacttgaa aaatctagca ggtatcaata aaagtcctca
    25561 agacttaaac ttggaggagc ttaaagggat tgatattttt gaaaatggct accagactaa
    25621 aatttcaagc tttgaagatt atctcagtcg agccaacgaa cttggtcaaa aattactaat
    25681 tgaaattaaa accagtaaaa aagatagtcc agacatgatg aaccgctttt tagcccgtta
    25741 tgctgcaaag ctcaagattt atggacatca aatccagtct ttagactacc atgttgtcga
    25801 aaaagtaaga cagtatgatg ccgaactgcc agtttatttc atcatgccct acaattctgt
    25861 ctttcctaaa acaagagcga caggatatac tatggagtac tcaaccttgg atgaatattt
    25921 tgtaagcaaa ctatggacaa cggatcagaa actttatgtc tggactgtca atgattcaga
    25981 agctatcagc aaatctcttc acttaggagt agatggagtg attacagatg atttggaaaa
    26041 agttcagcgg gaaatagaag tagcccaaga agatccagaa tatacggatt tgctcttgaa
    26101 aaaagcattg gaattctttg aattttagta ataaaaaaga ggaacggttg ttcctcccat
    26161 gataggtaag tattcttgtg aatgcttgct tttttgtggt tgcaatccgt ttacgagaat
    26221 tgtttgtatt gttcttgttt caatttactt tatagtgctt tgaagttgga atgctacact
    26281 ataacttct
//
LOCUS       DBERCW010000028        25605 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.028, whole genome shotgun sequence.
ACCESSION   DBERCW010000028 DBERCW010000000
VERSION     DBERCW010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.028"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            85..582
                     /locus_tag="ACL72M_001464"
     CDS             85..582
                     /locus_tag="ACL72M_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGS0716578.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            582..2237
                     /gene="dnaX"
                     /locus_tag="ACL72M_001465"
     CDS             582..2237
                     /gene="dnaX"
                     /locus_tag="ACL72M_001465"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGS0716579.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2265..2459
                     /locus_tag="ACL72M_001466"
     CDS             2265..2459
                     /locus_tag="ACL72M_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGS0716580.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2609..3379
                     /gene="sufC"
                     /locus_tag="ACL72M_001467"
     CDS             2609..3379
                     /gene="sufC"
                     /locus_tag="ACL72M_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGS0716581.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEGDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3407..4669
                     /gene="sufD"
                     /locus_tag="ACL72M_001468"
     CDS             3407..4669
                     /gene="sufD"
                     /locus_tag="ACL72M_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGS0716582.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4680..5906
                     /locus_tag="ACL72M_001469"
     CDS             4680..5906
                     /locus_tag="ACL72M_001469"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGS0716583.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5893..6333
                     /gene="sufU"
                     /locus_tag="ACL72M_001470"
     CDS             5893..6333
                     /gene="sufU"
                     /locus_tag="ACL72M_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGS0716584.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6387..7799
                     /gene="sufB"
                     /locus_tag="ACL72M_001471"
     CDS             6387..7799
                     /gene="sufB"
                     /locus_tag="ACL72M_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGS0716585.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(7998..9239)
                     /gene="pbp3"
                     /locus_tag="ACL72M_001472"
     CDS             complement(7998..9239)
                     /gene="pbp3"
                     /locus_tag="ACL72M_001472"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGS0716586.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9342..10451
                     /gene="cozE"
                     /locus_tag="ACL72M_001473"
     CDS             9342..10451
                     /gene="cozE"
                     /locus_tag="ACL72M_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGS0716587.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11097..11444
                     /gene="ssrA"
                     /locus_tag="ACL72M_001474"
     tmRNA           11097..11444
                     /gene="ssrA"
                     /locus_tag="ACL72M_001474"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11627..11714)
                     /locus_tag="ACL72M_001475"
     tRNA            complement(11627..11714)
                     /locus_tag="ACL72M_001475"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11678..11680),aa:Ser,seq:gga)
     gene            11877..12617
                     /locus_tag="ACL72M_001476"
     CDS             11877..12617
                     /locus_tag="ACL72M_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0716588.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12614..13525
                     /gene="pfkB"
                     /locus_tag="ACL72M_001477"
     CDS             12614..13525
                     /gene="pfkB"
                     /locus_tag="ACL72M_001477"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGS0716589.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13522..15474
                     /locus_tag="ACL72M_001478"
     CDS             13522..15474
                     /locus_tag="ACL72M_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS0716590.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHSYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQVP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15611..17863
                     /locus_tag="ACL72M_001479"
     CDS             15611..17863
                     /locus_tag="ACL72M_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGS0716591.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(18014..18442)
                     /locus_tag="ACL72M_001480"
     CDS             complement(18014..18442)
                     /locus_tag="ACL72M_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGS0716592.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            18580..19722
                     /locus_tag="ACL72M_001481"
     CDS             18580..19722
                     /locus_tag="ACL72M_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS0716593.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19731..20945
                     /gene="thiI"
                     /locus_tag="ACL72M_001482"
     CDS             19731..20945
                     /gene="thiI"
                     /locus_tag="ACL72M_001482"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGS0716594.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21080..21904
                     /locus_tag="ACL72M_001483"
     CDS             21080..21904
                     /locus_tag="ACL72M_001483"
                     /inference="COORDINATES: protein motif:HMM:NF012958.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="HGS0716595.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            21917..23083
                     /locus_tag="ACL72M_001484"
     CDS             21917..23083
                     /locus_tag="ACL72M_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS0716596.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            23591..25084
                     /locus_tag="ACL72M_001485"
     CDS             23591..25084
                     /locus_tag="ACL72M_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS0716597.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25097..>25605
                     /locus_tag="ACL72M_001486"
     CDS             25097..>25605
                     /locus_tag="ACL72M_001486"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0716598.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLLV"
BASE COUNT         7647 a         4716 c         5609 g         7633 t
ORIGIN      
        1 aaatattata gagcccaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg
       61 ctcctttttt gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg
      121 ttaaatgaag aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc
      181 aacgccagtg ctctcataaa atcacgtttt cctaataccg tatttgcagg cttttatttg
      241 ttcgatggaa aggaattggt tttaggcccc ttccaaggag gtgtttcctg catccgtatt
      301 gcactaggca agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga
      361 gatgtgacga cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg
      421 gtgccgatga tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt
      481 gaggattacg atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa
      541 aagacaacat gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc
      601 gaaaatatag aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc
      661 ttaaacaagc ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg
      721 gaacgggaaa aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag
      781 tgggtggcga accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag
      841 aagatgtcat tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc
      901 gtgataaatc tacctatgcg cctagccttg ctcgttataa ggtttatatc atagatgagg
      961 ttcacatgct gtctacaggg gcttttaatg ccctcctaaa gacgctggaa gaaccaacac
     1021 agaatgtagt ctttattttg gccactactg aattgcacaa gattcctgct actattctat
     1081 cccgtgtgca acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc
     1141 actatatctt agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca
     1201 ggcgggcgga aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga
     1261 cacagggaaa tgagctgacg actgctatct ctgaagaaat tactggcacc attagcctat
     1321 cagccttgga tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt
     1381 gcttgaatct tctttttgac aatggtaaga gcatgactcg ttttgtgacc gatcttttgc
     1441 actatttaag agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag
     1501 tctttgtaga aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa
     1561 cagtgagttt agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga
     1621 ccgtccgttt ggcggaaatc aagcccgaac cagctctatc aggagcggtt gaaaatgaaa
     1681 ttgctacgct gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gtaggtgcgg
     1741 ttcctaaaca agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg
     1801 tcgatcgcaa taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac
     1861 gtcaaaatct aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc
     1921 cggacaaggc tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc
     1981 ttgcttttga gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca
     2041 tgtttggtaa tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca
     2101 tggaggaatg gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaactg
     2161 aaaaagaagt agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga
     2221 aggtagagga agactaaaga aagatttcat gatacaataa gtttatgaat aaacaacaat
     2281 ttattattat ggcgctgttt acagctgctg agacctattt tttcaatgaa gcctggatga
     2341 ctggccgcta tattatggca gccttttggg caattttact ctttagaaat ttccgagtca
     2401 gttatgtgat gggcaaaatc gttgatgtca tcgatcagca ttttaatagg aaagactagc
     2461 cctcagcttc cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta
     2521 tatttataga atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt
     2581 aaaagttttg aaaaagaaag gaactatcat gtcagtatta gagattaaag atcttcacgt
     2641 tgagattgaa ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat
     2701 tgccgctatc atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg
     2761 aaatccaaac tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga
     2821 gttggaagtg gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga
     2881 aatccctgga attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaagg
     2941 tgatgagaag atttcagttc gtgagtttat tactaagcta gatgaaaaaa tggaattgct
     3001 caacatgaaa gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa
     3061 aaaacgcaat gaaattcttc aacttttgat gttggagcca acatttgctc ttttggacga
     3121 gattgactca ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat
     3181 gcgtggtgaa ggttttggtg ctatgatcat cactcactac caacgtcttt tgaactatat
     3241 cacacctgat gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga
     3301 attggctgcg cgtttggaac gtgaaggata cgcaaaatta gctgaagaac ttggctacga
     3361 ctacaaggaa gaattgtaat ttcctcgtat cttttaggag aagtaaatga ctagagaaaa
     3421 tattaaactt ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa
     3481 agcttttgac aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg
     3541 ttggaatctg ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt
     3601 cacagcttta gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca
     3661 aactccagtt gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga
     3721 agaaattcca gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa
     3781 gttggcggct taccacacag cttactttaa cagtggtgct gtactctata ttccagataa
     3841 cgtagaaatc acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc
     3901 gtttaacaag catattatga ttatcgctgg taaaaattct aagattagtt atctggagcg
     3961 tttagagtca cgcggtgaag gaagtgacaa agcaactgcc aatatcacag tggaagtgat
     4021 tgcacgttct ggtgcgcaag tcaagtttgc tgctattgac cgtctaggtg aaaacgtcac
     4081 tgcctacatt agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg
     4141 tgtcatgaac gaaggaaatg tcgttgctga ttttgatagt gacttgattg gtaatggtag
     4201 ccatgctgac ctcaaggttg tagctctttc aagtggtcgt caggtacaag ggattgatac
     4261 tcgtgtaact aactatggct gcaactctat cggaaatatc ctacaacatg gggttatcct
     4321 tgaaaaagca actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc
     4381 agatgcccaa caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa
     4441 cccaattctt ttgattgatg aaaatgacgt cactgcagga catgcagcct ctattggtca
     4501 ggtagatcca gaagatatgt actacctcat gagtcgtgga ttggataagg caactgcaga
     4561 gcgtttggtt gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt
     4621 tcgtgatgaa atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggaagccta
     4681 tgttagatgt agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg
     4741 aacctctggt ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag
     4801 ctattaacag ttactatgag caggacaatg ccaatgttca ccgtggtgtc cataccttag
     4861 cggaacgagc gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg
     4921 caggctctac aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg
     4981 cacgctttgc tgaggaaatt ctcactgagg gagaccaggt cttgatttca gtaatggaac
     5041 accattctaa tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct
     5101 atgtctatct taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata
     5161 aggttaaatt tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatca
     5221 aggaaatcac tcaattagcc caccaagttg gggcaatcat ggtagtggat ggtgctcaat
     5281 ctacacctca tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg
     5341 gtcacaagat ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg
     5401 agcaaatgtc tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatctg
     5461 ctagttggaa ggaattgcct tggaaatttg aggctggaac gccaaatatg gcaggagcta
     5521 ttggacttgc gactgcagtt gattatctgg aaaagattgg tatggatgcc gttgaagctc
     5581 atgaacagga attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca
     5641 tttacggttc tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc
     5701 tccatcctca cgatcttgcg acagctctgg attatgaagg agtggctgtt cgtgctggtc
     5761 accattgtgc gcaacccttg cttcagtatt tggaagtccc agcaacagct cgtgcaagtt
     5821 tttatatcta taataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa
     5881 aggagttttt caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac
     5941 cattcgaaaa atccacatca ccaagggaag ttagaagacg ctgagcaaat cagtctcaac
     6001 aatccgactt gtggagatgt catcaatctc tctgtcaagt ttgatgcaga ggaccgtttg
     6061 gaagatattg cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg
     6121 acagatgccg ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct
     6181 gaaatggttc aagggcaaaa agatgagcgt caagaccaac ttggagacgc ggcattcttg
     6241 tcaggtgttg ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt
     6301 aagaaaacaa ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta
     6361 ttagaaatga agaaagaaag gatattatgg ctgaagaaag agtagaacca aaaccaattg
     6421 accttggtga atataaattt ggtttccatg acgatgtaga gcctgtctta tcgacaggaa
     6481 aaggactcaa cgaaggtgtt attcgtgaat tatctgctgc taagggtgag cctgagtgga
     6541 tgttggagtt ccgtttgaag tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg
     6601 gagcagactt gtcagagatt gactttgatg acttaatcta ctaccaaaaa ccatctgaca
     6661 aaccagcccg ttcttgggat gatgtacctg aaaagattaa agaaaccttt gaacgtatcg
     6721 ggattccaga agctgaacgt gcttatttag caggggcttc tgcccagtac gagtcagaag
     6781 tggtttacca caacatgaag gaagagttcc aaaaattagg tattatcttt acagatacag
     6841 attccgcact caaggaatac ccagacttat ttaatcaata ctttgcgaag ttggtaccgc
     6901 cgacagataa caagttggca gccctcaact cagcagtatg gtcgggtgga acttttatct
     6961 acgtgccaaa aggtgtcaag gtagatattc cacttcaaac ttatttccgt atcaataacg
     7021 aaaatatagg tcagttcgaa cgtaccttga ttatcgttga tgagggagca agcgtccact
     7081 acgtagaagg atgtacagca ccaacatatt caagcaatag cttacacgct gccattgtag
     7141 aaatttttgc tttggacgga gcttatatgc gttatacaac tatccaaaac tggtctgata
     7201 acgtctataa cttggtaaca aagcgtgcta aggctcaaaa ggatgccact gttgagtgga
     7261 ttgatggaaa cttgggtgcc aaaacgacta tgaaatatcc atctgtttac cttgatggag
     7321 aaggagcgcg tggtaccatg ctctctatcg cctttgctaa tgcagggcaa caccaagaca
     7381 cgggtgctaa gatgattcac aatgctccac ataccagctc gtctattgtg tctaaatcca
     7441 tcgctaaagg tggaggaaag gttgactacc gtggacaagt cacctttaac aagaactcta
     7501 agaaatctgt ttcccacatt gaatgtgata ccattatcat ggatgacttg tcagcatcag
     7561 atactattcc atttaatgaa attcacaact cgcaagtggc tttggaacac gaagccaaag
     7621 tatctaagat ttcagaagag caattgtatt atctcatgag ccgtggattg tcagaatctg
     7681 aggcaactga aatgattgtc atgggatttg tagaaccctt tacaaaagaa cttccaatgg
     7741 aatacgcagt tgagctgaac cgcttgatta gctatgaaat ggagggatca gttggataaa
     7801 atttgatttt atactcttcg aaagtctctt caaaccacgt cagcatcgcc ttaccgtatg
     7861 tatggttact gacttcgtca gtttcatcta caacctcaaa acagtgtttt gagcaacctg
     7921 cggctagctt cctagtttgt tctttgattt tgaagatgaa cttgtatcaa aaaatcgcgg
     7981 tttaaaatcg cgatttttta taatttctcg ttaacaaagc ggacaaactg attccaccaa
     8041 acttttaaga agaaggcttt ttcaattttc ttgtctgcta ccatttcgaa actagggcgc
     8101 tctgtggtga tgtaaccttg accaatcaag tccttgtctt cataagtcaa atggccaacc
     8161 actgttccag cttcaagtgg tgctgggatt gctttggaat caggtgtgaa ttgaacagat
     8221 tgggaagatt gattcccaac acgttctatt agatagatat cctctggagc cactgcagtt
     8281 actgtatctt cttttccatc ttgtacaggg gttttgctat cttgataggc atcgccttgt
     8341 tgaacgattt tgcgaagtgt aaatgtagaa gaaatataat ccattaggga agatgtagct
     8401 gtaaatcgag cgtaaggatt attgtcttga tgatctgcat ttaaaacaac tgtgatgact
     8461 ctcatgcctt tttcgacagt agtaccaaca aaagactctc cagccttatc tgttgttcct
     8521 gtttttagcc catcaaaacc accacggtaa gcaggcatac cttctaacat gtagttggtt
     8581 gaagtgattg tcatcccagc aaaagtagaa gaaggttttt tggtgatttc taagacttgt
     8641 gggtattttt tgatgaggtt gcgagcaacg atagcgacat cataagcact aagcttattt
     8701 tcctcatctt ttttagaacc tgggtaaatg ttatccccta gagtttcatt gttaagacct
     8761 gtcgtattga caacagtggc atcctgaatt ccccattcca agagttttgc ccgcatcata
     8821 tcgacgaaat ctttttctga gccagcaatt ttctcagcta gggcaatagc ggcgctgttg
     8881 gcactagata ccagagttgc ttcaagcaac tcttcgacag tataattacg ggcctccata
     8941 ggaatattac tggcttcaga atttgtcgtc aattgataag gataatcaga aatatctaca
     9001 ggagtggaga gggtaatact tccgttttcc aaagcttcat agaccagata aacagtaatc
     9061 aattttgtta tggaagcaat ttcgacaggt tgcgttgcat ccttctcata gagaatttta
     9121 ccagtatttg cctcaacagc aatcgcatgt ttagcggcaa tggtaaaatc ttgagcaaca
     9181 gcagtagaag caccccctaa aagagagaca gttaacaaag ttaaaaatat ttttttcata
     9241 gtagtcttat tctatcataa agaaaaaaaa tattcttgct ttaataattc atctgttaag
     9301 ctttttgaaa atatggtaaa ataaagtgag ggaggtaact catgtttcgt agaaataaat
     9361 tatttttttg gaccacagaa attttactct taaccatcat cttttaccta tggagacaga
     9421 tgggatcttt gattaaccct tttgttagcg tgcttaatac aattatgatt ccatttttat
     9481 tagggggctt tctttattat ttgacaaacc ctattgttac tttcttaaat aaagtctgta
     9541 aactcaatcg tttgcttggt attttaatta ccttgtgtac tttggtctgg ggaatggtca
     9601 taggtgttgt ctatctctta cctattttga ttaatcagtt atctagtttg attatatcta
     9661 gtcaaactat ttatagtcga gtacaagact taatcataga cttatctaat tatcctgcgc
     9721 tccagaattt ggatgtagaa gctacaattc agcagttaaa cttatcctat gttgatattc
     9781 ttcaaaatat cctaaatagc gtatcaaata gtgtggggag cgtcttgtca gctcttatca
     9841 gtactgtttt gattttgatt atgactccag tttttttggt ttatttctta ttagatggac
     9901 ataaattctt gcccatgctt gaaagaacga ttctaaagag ggatcgcttg catattgcag
     9961 gcttattaaa gaatttaaat gcgacgattg ctcgctatat tagtggagtt tcgattgacg
    10021 caatcattat aggttgtttg gcttatattg gctatagtat tattggttta aaatatgctt
    10081 tagtttttgc cattttttct ggtgtagcca atttaattcc ttatgtgggg ccaagtattg
    10141 gtttgattcc tatgatcatc gcaaatatat tcactgatcc ccatagactg ctgattgcag
    10201 tgatttatat gcttgttgtt cagcaggtag atggcaatat cttatatcct cgaattgtag
    10261 gaagtgttat gaaggttcat ccaatcacga ttttagtttt acttttgttg tcaagcaata
    10321 tctatggtgt agttggaatg attgtcgcag tgccaaccta ttctatcttg aaagaaattt
    10381 ctaagttctt atcccgtttg tatgaaaatc ataaaataat gaaagaacga gaaagagaat
    10441 tagctaagta aaagtcagga gaaccctgat ttttctttac tggaagtggc ctttagatta
    10501 gaagactgaa aataagttaa agtcttaaac taattttcac agctaagaat agtagaagtt
    10561 aatctgataa aaatcgaaaa aaccagtgga attccgtgtc agggtaagtt ccactggttt
    10621 tcatagtcta ttaaagttcg aatgaaacct atttataata tattgaaact agaatagtac
    10681 acctctaatt ctaaaacatt gttagaaatc gatttgactg tcctgatcta ttcgtactat
    10741 tcttatttca ttttactata ttttggtgca ataagtgaaa agtagtccga ataatataag
    10801 gattgatttt atagttttta aactcaaatg aattaaaata aagagagtac gaaaattctc
    10861 atctgaaagt attttagaat aattctcttc gtgaatttct tcaaaacaga tagcttcatc
    10921 ttaggtatgt gttaattgga tttcgtaagc tctatttaca atcgtaaagt tatgcactga
    10981 gaaagttgta gttagtcttc cagtttgcta aatttctcga atagtatctt ttttaggtat
    11041 gtgatttctt tttgcatttt tgagttagat aaggtataat ggttttattg tcttttgggg
    11101 tcgttacgga ttcgacaggc attatgaggc atattttgcg actcgtgtgg cgacgtaaac
    11161 gctcagttaa atataactgc aaaaaataac acttcttacg ctctagctgc ctaaaaacca
    11221 gcaggcgtga cccgatttgg attgctcgtg ttcaatgaca ggtcttatta ttagcgagat
    11281 acgattaagc cttgtctagc ggcttgataa gagattgata gactcgcagt ttctagactt
    11341 gagttatgtg tcgaggggtt gttaaaataa tacataacct atggttgtag acaaatatgt
    11401 tggcaggtgt ttggacgtgg gttcgactcc caccggctcc attattcctt tgcattcttt
    11461 tgcattcctt ggtaaaacgt tgttaaatca acgtttttta tttttatctt tggtattcct
    11521 ttgcattctt ttgctaaaaa gggagtcaca aacagaccct attttaaaaa aaggatagaa
    11581 aaaaggatac aacatttgtc gcatcctaga aataatcttt tttcgacgga agacatggga
    11641 ttcgaaccca cgcacgctat tacacgccta ccgcgtttcc aacacggcct cttaagcctc
    11701 ttgagtaatc ttccaatact tactcaaata gtctaccata aaggctctta tcttgcaata
    11761 aaaattctag aaataagaaa aaatgataga ttttgaaaga aaatgataaa aaatgcttga
    11821 cttcgaaaga aagtatgata gaatgaatag tgtaaacgat aacaggaggt gattcagtgt
    11881 taaaaacaga acgtaaacaa ctaattttag aggagttaaa tcaacatcat gtagtttctc
    11941 tagaaaaatt agttagtttg ctagaaacgt cagaatcaac ggttcgaaga gacttggatg
    12001 agttggaagc ggaaaacaag cttcgtcgtg tgcatggtgg agcagaactc ccccactcct
    12061 tacaggaaga agaaaccatt caagaaaaat ctgtcaaaaa ccttcaagaa aagaagttgc
    12121 tggctcagaa agcagcctct ctcattaaag aaaaagatgt catctttatc gatgctggaa
    12181 caacaactgc ttttttgatt catgaattgg tcaataagaa tgttacagtt gtgaccaact
    12241 ccattcacca tgccgctcag ttggttgaaa agcagattcc aactgtcatg gttggaggaa
    12301 acgtcaagac ggcgacagat gctagtatcg ggggcgttgc tcttaaccag attaaccaat
    12361 tgcactttga ccgtgccttt atcggaatga atggtgttga cgatggctat tatacgactc
    12421 ctgatatgga ggaaggagct gtgaaaagag ctattttgga gaatgccaag cagacctacg
    12481 tcttggtgga ttcgtcaaaa attggacaaa cttgctttgc caaggtagca ccactcaaac
    12541 gcgctatcgt tatcactagt caagggcatg agctcttgca ggttattaag gagaaaacgg
    12601 aggtaataga agtatgattt atacagtcac actcaatcca tccattgact atatcgttcg
    12661 tttggaccaa gtcaaagttg gtagtgtaaa tcgtatggac agtgatgata agtttgctgg
    12721 tgggaaagga atcaatgtca gccgtgtctt gaaacgtttg aatataccaa atacagcgac
    12781 gggatttatc ggtggcttta ctggtaaatt tatcacagat actttagcag aggaagaaat
    12841 cgagacacgt tttgtccagg tggcagaaga tactcgtatc aatgttaaaa tcaaagcaga
    12901 ccaagaaaca gaaatcaacg gaacgggtcc aactgttgaa ccggttcagc tagaagaatt
    12961 gaaagctatt ttatctagtc tgacagcaga agatacagtt gtctttgcag gttcaagtgc
    13021 taaaaatcta ggcaatgtta tctataagga tttgatttcc ttgacgcgcc agactggtgc
    13081 gcaagtggtc tgtgactttg aaggacagac cttaattgat agtttggact accagcctct
    13141 tcttgtaaaa ccaaacaatc atgaacttgg agcgattttt ggggttaaac tcgaaagttt
    13201 agatgaaatt gagaaatacg ctcgtgagtt actggctaag ggtgctcaaa atgttattat
    13261 ctctatggct ggtgatggcg cccttcttgt cacatctgag ggagcttact tcgctaaacc
    13321 aatcaaagga acagtcaaaa attcagttgg agctggtgat tctatggttg ctggattcac
    13381 aggtgaattt gtcaaatcaa aagacgcagt agaagccttc aaatggggag tggcttgcgg
    13441 aacggcaact accttctcag atgacttggc aacggcggaa tttattaaag aaacatatgg
    13501 aaaagttgag gtagaaaaaa gatgaaaatt caagacctat tgagaaaaga tgtcatgttg
    13561 ctagatttgc aggcaactga aaaaacagct gtcatcgacg agatgattaa aaatttgaca
    13621 gagcacagtt atgtaacaga ttttgaaaca tttaaagaag gaattttggc gcgtgaagct
    13681 ttgacttcta ctggtttggg tgatggaatc gcaatgcctc acagcaaaaa cgctgctgtc
    13741 aaagaagcga cagttctatt tgctaagtca aataagggtg ttgactacga gagcttggat
    13801 ggacaagcaa ctgacctctt cttcatgatt gcagctccag aaggtgccaa tgatactcac
    13861 ttggcagcct tggcagaatt gtctcaatac ttgatgaaag acggttttgc agacaaactt
    13921 cgtcaagcaa catctgcaga ccaagttatc gaactttttg accaagcttc agaaaaaact
    13981 gaggaacttg ttcaagtacc tgctaatgac tctggtgact ttatcgtagc tgttacagct
    14041 tgtacaacag gtattgccca cacttacatg gcccaagaag cccttcaaaa agtagctgct
    14101 gaaatggggg ttggtatcaa ggtcgaaacc aacggtgcta gcggtgttgg aaatcaacta
    14161 actgcagaag atatccgtaa ggctaaagct attatcattg cagcagacaa ggccgttgaa
    14221 atggatcgat ttgatggaaa accattgatc aatcgtccag ttgctgacgg tatccgtaag
    14281 acagaagagc taattaactt ggctctttca ggagatactg aagtctaccg tgccgctaat
    14341 ggtgcaaaag ctgcaacagc ctctaacgaa aaacaaagcc ttggtggtgc cttctacaaa
    14401 cacttgatga gtggtgtatc tcaaatgtta ccattcgtta tcggtggtgg tatcatgatt
    14461 gcccttgcct tcttgattga cggtgctttg ggtgttccaa atgaaaacct tggcaatctt
    14521 ggttcttacc atgagttagc ttctatgttc atgaaaattg gtggagctgc ctttggtttg
    14581 atgcttccag tctttgcggg ttatgttgcc tactctattg ctgaaaaacc aggtttggta
    14641 gcaggtttcg tggctggtgc tattgccaaa gaaggttttg cctttggtaa aattccttat
    14701 gccgcaggtg gtgaagcaac ttcaactctt gcaggtgtct catctggttt cctaggtgcc
    14761 cttgttggtg gatttatcgc aggtgccttg gttcttgcca tcaagaaata cgttaaagtt
    14821 cctcgttcac tcgaaggtgc taaatcaatc cttctattgc cacttcttgg aacaatcttg
    14881 acaggatttg ttatgctagc tgtgaatatc ccaatggcag caatcaacac tgctatgaat
    14941 gacttcctag gcggtcttgg aggaggttca gctgtccttc ttggtatcgt ccttggtgga
    15001 atgatggctg ttgacatggg tggaccagtt aataaagcag cttatgtctt tggtacaggt
    15061 acgcttgcag caactgtttc ttcaggtggt tctgtagcca tggcagcagt tatggctgga
    15121 ggaatggtgc caccacttgc aatctttgtc gcaactcttc ttttcaaaga taaatttact
    15181 aaggaagaac gtaactctgg tttgacaaac atcatcatgg gcttgtcatt tatcactgag
    15241 ggagcgattc catttggtgc cgctgaccca gctcgtgcga ttccaagctt catccttggt
    15301 tcagcagtag caggtggact cgttggtctt actggtatta aactcatggc gccacacgga
    15361 ggaatcttcg ttatcgccct tacttcaaat gctctccttt acctcgtttc tgtcttggta
    15421 ggagcaatcg taagtggtgt ggtttatggt tacctacgca aaccacaagc ataaaaaata
    15481 gaaaaatgaa aagattggac cgtttggtgc agtctttttc tctttccgaa atgcctgtga
    15541 aatatggtat aatagaagaa tggcaaacaa gaatacaagt acaacaagac ggagaccgtc
    15601 taaagcagaa ctggaaagaa aagaagcgat tcaacgaatg ttgatttcgt taggaattgc
    15661 gattttattg attttcgcag ccttcaaatt aggggctgca ggtataaccc tttataattt
    15721 aattcgcttg ctagtgggta gcctagctta tctggcgata ttcggcctat taatctatct
    15781 cttttttttc aagtggatac gaaaacagga aggactctta tctggctttt tcaccatatt
    15841 tgctggctta ctcttgattt ttgaagccta cttggtttgg aaatatggtt tggacaagtc
    15901 cgttctaaaa gggaccatgg ctcaggttgt gacagatctg actggttttc gaacgactag
    15961 ttttgctgga gggggcttga tcggggtcgc tctttatatt ccaacagctt ttctcttttc
    16021 aaatatcgga acttacttta ttggttctat cttgatttta gtgggttctc tcctagtcag
    16081 cccttggtct gtttacgata ttgctgaatt tttcagtaga ggctttgcca aatggtggga
    16141 agggcacgag cgtcgaaaag aggaacgctt tgtcaaacaa gaagaaaaag ctcgccaaaa
    16201 ggctgagaaa gaggctagat tagaacaaga agagactgaa aaagccttac tcgatttgcc
    16261 tcctgttgat atggaaacgg gtgaaattct gacagaggaa gctgttcaaa atcttccacc
    16321 tattccagaa gaaaagtggg tggaaccaga aatcatcctg cctcaagctg aacttaaatt
    16381 ccctgaacag gaagatgact cagatgacga agatgttcag gtcgattttt cagccaaaga
    16441 agcccttgaa tacaaacttc caagcttaca actctttgca ccagataaac caaaagatca
    16501 gtctaaagag aagaaaattg tcagagaaaa tatcaaaatc ttagaagcaa cctttgctag
    16561 ctttggtatt aaggtaacag ttgaacgggc cgaaattggg ccatcagtga ccaagtatga
    16621 agtcaagccg gctgttggtg taagggtcaa ccgcatttcc aatctatcag atgacctcgc
    16681 tctagccttg gctgccaaag atgtccggat tgaagcacca atccctggga aatccctaat
    16741 cggaattgaa gtgcccaact ccgatattgc cactgtatct ttccgagaac tatgggaaca
    16801 atcgcaaacg aaagcagaaa atttcttgga aattccttta gggaaggctg ttaatggaac
    16861 cgcaagagct tttgaccttt ctaaaatgcc ccacttgcta gttgcaggtt caacgggttc
    16921 agggaagtca gtagcagtta acggcattat tgctagcatt ctcatgaagg cgagaccaga
    16981 tcaagttaaa tttatgatgg tcgatcccaa gatggttgag ttatctgttt acaatgatat
    17041 tccccacctc ttgattccag tcgtgaccaa tccacgcaaa gccagcaagg ctctgcaaaa
    17101 ggttgtggat gaaatggaaa accgttatga actctttgcc aaggtgggag ttcggaatat
    17161 tgcaggtttt aatgccaagg tagaagagtt caattcccag tctgagtaca agcaaattcc
    17221 gctaccattc attgtcgtga ttgtggatga gttggctgac ctcatgatgg tggccagcaa
    17281 ggaagtggaa gatgctatca tccgtcttgg gcagaaggcg cgtgctgcag gtatccacat
    17341 gattcttgca actcagcgtc catctgttga tgtcatctct ggtttgatta aggccaatgt
    17401 tccatctcgt gtagcatttg cggtttcatc aggaacagac tcccgtacga ttttggatga
    17461 aaatggagca gaaaaacttc ttggtcgagg agacatgctc tttaaaccga ttgatgaaaa
    17521 tcatccagtt cgtctccaag gctcctttat ctcggatgac gatgttgagc gcattgtgaa
    17581 cttcatcaag actcaggcag atgcagacta cgatgagagt tttgatccag gtgaggtttc
    17641 tgaaaatgaa ggagaatttt cggatggaga tgctggtggt gatccgcttt ttgaagaagc
    17701 taagtctttg gttatcgaaa cacagaaagc cagtgcatcc atgattcagc gtcgtttgtc
    17761 agttggattt aaccgtgcga cccgtctcat ggaagagctt gagatggcag gtgtcattgg
    17821 tccagctgaa ggtaccaagc caagaaaagt attgcagcaa taaaaaatag cttctttcca
    17881 aggttggaag gagctatttt actggctatt gattactttt atactcttcg caaatctctt
    17941 caaaccacgt cagcttcgcc ttgccgtact caagtactgt ctacggctag cttcctagtt
    18001 tgctctttga ttttcattga gtattatttt ctgaagttgg agtattgggc tgtttttcat
    18061 tttcagtggc aggtttactt gtagcaggtg tagtagagtc ctgagttgct gttttctgat
    18121 cttctttttt ctcttccttg acgctagatt ttggcgtttc ttcttgttgt gttttttctt
    18181 gagaagtgtt attttcctta tttggagtag tattttcctg aggggattct ttttgaattt
    18241 ctttgacaaa ggttgtcgtc tggcttgtcg taggttcttt tttagtattt ttattattat
    18301 tatccaaggc gttcatgatc gtgatacccg cggtaatcaa accaaggata ctaccgatag
    18361 tagtaatggt tttttgaaaa acagtaaagc cttttttgat atgttctgtt ttcggttttg
    18421 aagttctacg atagttagac atacattctc tcctttgatt atgatttatt atactctgtt
    18481 tctttaaaaa aatcttaaaa aaagagaaat tgccctttct tgtcgcaggc tccgtttcat
    18541 gatacaatag aaggagtgat tttagaaagc gtgagaaaca tgatttactt tgataattcg
    18601 gcgacgacca ggccctatcc agaagccctt gaaacctata tgcaggtggc ttcaaaaatt
    18661 ttaggaaatc catctagtct ccatcgtttg ggagaccagg caacacgaat tttagatgct
    18721 tcccgtcaac agattgcaga tttaatcggt aagaaaagtg atgaaatctt ctttacatct
    18781 ggtgggacag aaggggataa ctggatcatc aagggagtag catttgaaaa agcccagttt
    18841 ggcaagcaca tcatcgtatc agccattgaa catccagcag ttaaggaatc agccctctgg
    18901 ttgaaagctc aaggttttga agtggatttt gctccagttg ataacaaagg atttgtggat
    18961 gttgaggcgc tagaagattt gataagacct gatacgaccc tcgtttccat catggctgtg
    19021 aacaatgaaa tcggctctat ccaacctatt gaggctattt cagaattctt ggcagacaag
    19081 ccaactattt ccttccacgt tgatgcggtt caggcgcttg ccaagattcc gactgaaaag
    19141 tatctgacag aacgagtgga tttcgcgact ttctctggtc acaagttcca cggaatccgt
    19201 ggtgttggtt ttatctatat caagtctggc aagaagatta cgcctctttt aacaggtggt
    19261 ggtcaggaac gtgattaccg ttcgacaact gaaaatgtgg caggaattgc agcgaccgct
    19321 aaggctctcc gtttatctat ggaaaagcta gatatcttta ggagcaagac tgggcagatg
    19381 aaggcagtga ttcgtcaagc acttctggac tatccggata tatttgtctt ttcagatgag
    19441 gaagacttcg cccctcatat tctgactttt ggaatcaagg gtgttcgtgg tgaggtcatt
    19501 gttcacgcct ttgaagacta tgatattttc atctcaacga cctcggcttg ttcgtccaag
    19561 gctgggaaac cagccggaac cctgattgct atgggagtgg acaaggataa ggctcagtca
    19621 gctgtgcgtc ttagtctaga ccttgaaaat gatatgagtc aggtcgagca gttcttgacc
    19681 aagctaaaat taatttacaa tcaaactaga aaagtaagat aggagcattc atgcagtatt
    19741 cagaaattat gattcgctac ggtgagctgt caaccaaggg caaaaatcgt atgcgtttca
    19801 tcaataaact tcgcaataat atttcagacg ttttgtctat ctatccccaa gttaaggtaa
    19861 cagcagatcg cgaccgtgcc cacgcttacc tcaatggagc agattacaca gcagtagcag
    19921 aatcgctcaa acaagtattt ggaattcaaa acttttcccc tgtttataag gttgaaaaat
    19981 ctgtagaagt tctgaagtct gctgtccaag agattatgca ggacatctac aaggaaggca
    20041 tgacctttaa aatctctagc aagcgtagcg accacacctt tgaattggac agtcgtgaac
    20101 tcaaccaaac gcttggaggg gctgtattcg aagccattcc aaacgtacaa gctcaaatga
    20161 aaagtcctga catcaatctt caggtggaga tacgtgaaga agcagcctat ctttcttatg
    20221 aaaccgttcg aggggcaggt ggattaccag tgggaacttc tggtaagggc atgctcatgt
    20281 tgtcaggggg aatcgattcc cctgtagctg gctatctagc gcttaaacga ggggtagata
    20341 tagaggcagt tcactttgcc agcccacctt acacgagtcc tggtgctctt aaaaaagccc
    20401 aagatttgac ccgtaaatta accaaatttg ggggaaatat ccagtttatc gaagttcctt
    20461 ttacagagat tcaagaggaa atcaaagcca aagcgccaga agcctacctt atgaccttga
    20521 cgcgtcgttt tatgatgcgt attactgacc gtattcgtga ggtacgaaat ggtttagtta
    20581 tcatcaatgg ggaaagtcta ggtcaagtag ccagccaaac ccttgaaagt atgaaggcta
    20641 tcaatgctgt taccaacact cccatcattc gtcctgtggt taccatggac aagttggaaa
    20701 tcattgacat cgcccaggaa atcgatacct ttgacatttc aatccaaccg tttgaagact
    20761 gttgtactat ttttgcacca gatcgtccaa aaacaaatcc taaaattaag aatgcggagc
    20821 agtacgaagc gcgtatggat gttgaaggct tggttgagcg agcagtggct ggaatcatga
    20881 ttactgaaat cacacctcaa gccgaaaaag atgaagttga tgacttgatt gacaatctgc
    20941 tctaattcag aaaatccaaa agaatagcga aaatcagtaa aaaaagttag ttttttctct
    21001 aaaaacaggt aaaaaactaa ctttttttat ttttatgata taatgatata aaattttgaa
    21061 tatagagagt tttctgacaa tgaatcaatc ctacttttat ctaaaaatga aagaacacaa
    21121 actcaaggtt ccttatacag gtaaggagcg ccgtgtacgt attcttcttc ctaaagatta
    21181 tgagaaagat acagaccgtt cctatcctgt tgtatacttt catgacgggc aaaatgtttt
    21241 taatagcaaa gagtctttca ttggacattc atggaagatt atcccagcta tcaaacgaaa
    21301 tccggatatc agtcgcatga ttgtcgttgc tattgacaat gatggtatgg ggcggatgaa
    21361 tgagtatgcg gcttggaagt tccaagaatc tcctatccca gagcagcagt ttggtggtaa
    21421 gggtgtggag tatgctgagt ttgtcatgga ggtggtcaag ccttttatca agcacaaaac
    21481 aggttggttt gatggcatga tgacgacagg ttgctctatg ggagcctatc atgcactcaa
    21541 tttcttcctc cagcatccag atgtctttac caaagtgatt gctctcagtg gtgtttacga
    21601 cgcacgtttc tttgtcggcg attactacaa cgatgatgct atttaccaaa actcgccagt
    21661 agattatatt tggaaccaaa acgatggctg gtttattgac cgttaccgtc aggcagagat
    21721 tgtgctgtgt acggggcttg gagcctggga acaagatggt ttaccatcct tttacaagct
    21781 caaagaagcc tttgaccaga aacaaattcc agcctggttt gctgaatggg gacatgatgt
    21841 cgcccacgac tgggaatggt ggcgtaaaca aatgccttat ttcctcggta atctctattt
    21901 ataaaaggag ttacctatga attaccttgt tatttctccc tactatccac aaaactttca
    21961 acagtttacc atcgaactag ctaataaagg catcacagtc ttgggaattg gtcaagagtc
    22021 ttacgagcaa ttggatgagc ccttgcgcaa tagcttgacc gagtattttc gtgttgataa
    22081 tcttgagaac atagatgaag tcaaacgtgc agttgctttt ctcttttata aacatggtcc
    22141 aattgaccgc atcgagtctc acaatgaata ctggcttgag ctagacgcaa cactcagaga
    22201 acaattcaat gtttttggtg ccaaaccaga ggatctcaaa aagacgaaat ataagtctga
    22261 aatgaagaaa cttttcaaaa aagcaggtgt tcctgtggta cctggagctg ttatcaagac
    22321 ggaagcagat gttgatcaag cagtgaaaga aatcggtctt ccaatgattg ccaaacctga
    22381 taatggagtg ggagcagccg caacctttaa acttgagaca gaagacgata tcaatcactt
    22441 caagcaagaa tgggaccatt caacccttta tttctttgaa aaatttgtca cttccagcga
    22501 aatctgtacc tttgacgggc tcgtggacaa ggatggaaag attgtcttct caacaacctt
    22561 tgactacgcc tatacaccgc ttgacctcat gatttataag atggacaatt cttattatgt
    22621 gctcaaggat atggatccta aactgcgcaa gtatggggaa gcaattgtca aagaatttgg
    22681 tatgaaagaa cggtttttcc atattgagtt cttccgtgag ggggacgatt atattaccat
    22741 cgagtacaat aaccgccctg caggtggttt taccattgat gtttataact ttgctcattc
    22801 cttggacctt tatcgtggct atgcagctat tgtcgcagga gaggagttcc cggcgtcaga
    22861 ctttgaaact cagtattgtt tggctacttc tcgccgtgca aatgctcact atgtttattc
    22921 agaagaggat ttgcttgcca aatatagcca gcagttcaag gttaaaaaag tcatgccagc
    22981 tgccttcgcg gaacttcaag gagattacct gtatatgctg acaactccga gtcgacaaga
    23041 aatggatcag atgattgctg atttcggaca acgtcaagaa taagaactat cggattaagg
    23101 aaattcactc ccttaatcct tttgttttgt ctggtaaaaa ataagagcat cctaacaagg
    23161 tagctatcat aaaacttgtt cgataactat ttgaagcagg attaggtggc tagaaattga
    23221 attttaacat ttcaatttag tcatagtatt gtgttttcgt atccttaaat cagctaaaag
    23281 gatccatgac gacacctata cgatatagtt ttcaggatac caaaccagtc tattaatact
    23341 caatgaaaat caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg
    23401 aggttgtgga tagaactgac agagtcagta tcatatacct acggcaaggt gaagctgacg
    23461 tggtttgaag agattttcga agagtataaa atattcaggt gacgcataga tatagttaat
    23521 tgaagctttg tttgaaatct gataaaataa tgatattact aagttttaaa aactaaagaa
    23581 aagggaagat atgattacag gcgaattaaa aaataaaatc gatcagctgt gggaaattct
    23641 ttggacagaa ggaaacgcaa atcctttaac aaatattgaa cagttgactt atctcttatt
    23701 tatgaaagat ttggatagtg tcgagcttgg acgtgaaagt gatgctgaat ttctagggat
    23761 tccttatgag ggagtttttc caaaagataa acctgaatac cgttggtcaa cttttaaaaa
    23821 tataggagat gctcaggaag tttatcgttt aatgactcag gagatttttc cgtttattaa
    23881 aaatctcaag ggggatacag atgatacagc cttttcacga tatatgcgag aagctatttt
    23941 tcaaataaat aaacctgcta cgcttcaaaa ggcaatttct atcttagatg tttttccaac
    24001 taggggatta gatgtagatt ttgataatga caaacaaagt attactgata tcggagatat
    24061 ctatgaatat ctgttatcaa aattgtcgac cgcaggtaaa aatggacagt tccgtacacc
    24121 tcgtcacatc atcgatatga tggttgagtt gatgcaaccg actatcaaag atatcatctc
    24181 agatcccgct atgggttctg ctggcttctt agtatctgct agccgttact taaagcgtaa
    24241 gaaagatgaa tgggaaacca atacagataa tatcaatcat tttcataatc agatgtttca
    24301 tggaaatgat acggatacga ctatgttgag acttggggcg atgaacatga tgctacatgg
    24361 agtagaaaat ccacaaatca gttaccttga ctcgctgtct caagataatg aagaagccga
    24421 taaatatact ttggttttag caaatcctcc ttttaagggc tcacttgact acaattcaac
    24481 ctctaatgac cttcttgcaa ccgtaaaaac caaaaaaaca gaattactct ttctttctct
    24541 tttcttgcga actttaaaac caggtggacg agcagcagtt atcgtacctg atggtgtcct
    24601 ttttggttcg tctaaagctc ataaaggaat tcgtcaggaa attgtagaga atcataagct
    24661 tgatgctgta atctcaatgc ctagtggtgt gttcaagcct tatgctggag tttcaactgc
    24721 cattctcatc tttacaaaaa ctggtaatgg tggtactgac aaagtctggt tttacgatat
    24781 gaaagcggat ggtttaagtt tggatgataa gcgacaaccg attagcgaca atgatattcc
    24841 agatattatc gaacgctttc atcatcttga aaaagaagca gaacgtcaga gaacggatca
    24901 atctttcttt gttccagttg ctgagataaa ggaaaatgat tatgatttgt ctatcaataa
    24961 atataaagag attgagtatg aaaaagttga gtatgaacca acagaggtca tcttaaagaa
    25021 aatcaatgat ttagaaaaag aaattcaagc tggcttggct gaattagaaa aattactcaa
    25081 gtagggaggt ggctgtatga aaaaagtgaa gttgggggaa gtcttatctc taaaaaaagg
    25141 caagaaagcc actgtacttg ctgaacaaac aactctaagc caacgttata ttcaaataga
    25201 tgatttaaga aataataata atttaaaatt cactgaaagt ttaaatatga ctgaagcact
    25261 cccagatgat attctgatag catgggatgg agctaatgca ggaacagttg gttatggatt
    25321 atcgggagct gttggtagta caattacggt cttaaaaaag aatgagcgat acaaagaaaa
    25381 aattatatca gattacttgg gagtcttttt ggaaagtaaa tcgcagtatt tacgagaaca
    25441 ttcaacaggt gcaacaattc ctcatttaaa caagaatata ttacttgatt tacaattaga
    25501 attgctaggt atcgaagaac aagagaacat tatctgtatt cttaatacga ttaaagggct
    25561 tattactaaa agaaaattgc agttagatga actaaacttg ctcgt
//
LOCUS       DBERCW010000029        25271 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.029, whole genome shotgun sequence.
ACCESSION   DBERCW010000029 DBERCW010000000
VERSION     DBERCW010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.029"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..480)
                     /locus_tag="ACL72M_001487"
                     /pseudo
     CDS             complement(1..480)
                     /locus_tag="ACL72M_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1028..3586
                     /locus_tag="ACL72M_001488"
     CDS             1028..3586
                     /locus_tag="ACL72M_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS0716599.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            3885..4724
                     /gene="licT"
                     /locus_tag="ACL72M_001489"
     CDS             3885..4724
                     /gene="licT"
                     /locus_tag="ACL72M_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGS0716600.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            4742..6580
                     /locus_tag="ACL72M_001490"
     CDS             4742..6580
                     /locus_tag="ACL72M_001490"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGS0716601.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            6593..8008
                     /locus_tag="ACL72M_001491"
     CDS             6593..8008
                     /locus_tag="ACL72M_001491"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS0716602.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            8600..9646
                     /gene="pheS"
                     /locus_tag="ACL72M_001492"
     CDS             8600..9646
                     /gene="pheS"
                     /locus_tag="ACL72M_001492"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGS0716603.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            9646..10155
                     /locus_tag="ACL72M_001493"
     CDS             9646..10155
                     /locus_tag="ACL72M_001493"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716604.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            10232..12634
                     /gene="pheT"
                     /locus_tag="ACL72M_001494"
     CDS             10232..12634
                     /gene="pheT"
                     /locus_tag="ACL72M_001494"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGS0716605.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAVASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(12702..13703)
                     /locus_tag="ACL72M_001495"
     CDS             complement(12702..13703)
                     /locus_tag="ACL72M_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS0716606.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            13859..14305
                     /locus_tag="ACL72M_001496"
                     /pseudo
     CDS             13859..14305
                     /locus_tag="ACL72M_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            14431..14697
                     /locus_tag="ACL72M_001497"
     CDS             14431..14697
                     /locus_tag="ACL72M_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0716607.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            14958..17207
                     /gene="metE"
                     /locus_tag="ACL72M_001498"
     CDS             14958..17207
                     /gene="metE"
                     /locus_tag="ACL72M_001498"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGS0716608.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            17271..18137
                     /gene="metF"
                     /locus_tag="ACL72M_001499"
     CDS             17271..18137
                     /gene="metF"
                     /locus_tag="ACL72M_001499"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGS0716609.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            18822..21035
                     /gene="pnp"
                     /locus_tag="ACL72M_001500"
     CDS             18822..21035
                     /gene="pnp"
                     /locus_tag="ACL72M_001500"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGS0716610.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDLEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            21051..21668
                     /gene="cysE"
                     /locus_tag="ACL72M_001501"
     CDS             21051..21668
                     /gene="cysE"
                     /locus_tag="ACL72M_001501"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGS0716611.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            21680..22564
                     /locus_tag="ACL72M_001502"
     CDS             21680..22564
                     /locus_tag="ACL72M_001502"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716612.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            22651..23994
                     /gene="cysS"
                     /locus_tag="ACL72M_001503"
     CDS             22651..23994
                     /gene="cysS"
                     /locus_tag="ACL72M_001503"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGS0716613.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            23987..24373
                     /locus_tag="ACL72M_001504"
     CDS             23987..24373
                     /locus_tag="ACL72M_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGS0716614.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            24377..25261
                     /locus_tag="ACL72M_001505"
     CDS             24377..25261
                     /locus_tag="ACL72M_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0716615.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGFLSTIVGL"
BASE COUNT         7718 a         4481 c         5592 g         7480 t
ORIGIN      
        1 ttaagaaagt gatctcggat gacagcttgt gttctaccct caagaacagt gatgatatcg
       61 agcttttcaa aatcttgcgc aataaagctc atctccatct cccgattgaa acagtcactc
      121 cccggactgt ttcaacgtcc caagacataa tcttaggcag atttctaaaa ttacactcaa
      181 agtggaagtc attgagcttt cgaatgacag ttgaagttga aatggccagc tgatgggcaa
      241 tatcggtcat agaaatcttt tcaattaact tttgcgcaat cttttggttg ataatacgag
      301 gaatttggtg atttttcttg atgatagaag tttcagcgac catcattttc aagcaatgat
      361 agcacttaaa acgacgtttt ctaaggagaa ttctagtagg cataccagtc gtttcaaggt
      421 aaggaatttt atagggtctt taatgtctag taattttgtg ataaaatgta attgttccat
      481 atgattcttt ctaatgagtt gttttgtcgc ttttcattat agatcttatg ggactttttt
      541 tctacccaaa ataggctcca taatatccat agggaattta cccactacaa atattataga
      601 gcccaaagtt ttaggtcgct tgataatatg cgttttttga attttataga ctgctcgttt
      661 aaactctatt tacttcgtac cttctggagc gagacggaat attagtcaca tacaaaatga
      721 gtactattag gattttattt tcatgtacaa tttcagccag tcttgttata atcagcctat
      781 aggaatcaag gaggtgactc ttatggctgt ttttgtgtct ttggatggaa ttgtggtaga
      841 agtccttgat gtcttttctt cttttaatgg ggatagtgag tttttcttgt gtatagcatt
      901 ttgaatctgg aataggacgc catgactgct aaaagatttc tataaattaa tttgattttc
      961 ctaatcaatt tgttcatatc ttatttcatt ccactataaa cgtcttaaag acaagagtca
     1021 gtttgttatg gaacgctctc agttcgagga gatgttccaa cttcaaagta gtcgcttgac
     1081 gacgcaagaa aaattacaat tgtttacctc tgtgtttgct ggccgttatg atgtttatgc
     1141 taagaatttt atcaatgaac aagggaaaat tcagtatttt ccttcctatg attatggttg
     1201 gaagcagttg ccacctgaaa aacggagttt ccagacattg acgaactccg ttttgaaatc
     1261 tcattttcgt ggggaggcag ctatcggtat ctttcctatg cacttagatg atagctgtta
     1321 ttttttggta ctggatttgg atgaaggaga ttggaaagaa gctggtttaa ccattcgaag
     1381 aatagccagg gaacgccaga tggaagccca tttagagatt tctcgttcgg gttacggact
     1441 ccatatttgg ttcttctttg aggaagcgat tctgagtcga aaggctcgcc tgtttggaaa
     1501 gaaactatta gaattggcta tgcaggaaag tatgcaactg tcctttgatt cttttgatcg
     1561 catgtttcca aatcaggatg ttcttcctaa aggtggattt gataatttaa tttcccttcc
     1621 ttttcaagga gaagcttatc atcaagggcg aacggtcttt gtggatgaac agtttcagcc
     1681 ttatgaagat caatggaggt atctacaaga aattcagaag atttcaactg ctaaagtggc
     1741 actgttaatc caagaggagt taggcaagca agaattggac aaggagttga agatcgtctt
     1801 atccaatatg atccaacttg aaaaatcgtc tgtgacaccc aagacactgt ttttcttgaa
     1861 aaatatggct tcattttcta atcccgaatt ttatttaaag caggctatgc gacagccaac
     1921 ctatcaaatt cctgagagaa tgtatttatt tggagaatcc gatcattatt tatggttgcc
     1981 aagaggtttg ctgtatccat tgcaagataa atttaagcag gtatctgtgg aagataggag
     2041 aaaggtacaa aggtctatta gcgtggaatt taagggagaa ctcacttttg agcaagagtt
     2101 agccctgtca gatatgactt ctaaagaaaa tggtttactt catgcggaga ctggttttgg
     2161 gaagaccgtt ttaggtgctg ctcttatctc tgaacggaaa acaaaaacaa ttattctagt
     2221 ccataataag caactcttag accaatggct agatcgctta aactgctttt tgactttcga
     2281 agaggaggag gctatccgtt atacggcatc aggtcgtgaa aaggtaatcg gctatgttgg
     2341 acagtacggt gggactaaga aatggctgag taaactggtt gatgtcgtta tgattcaatc
     2401 tctatttaag ttggaaaata gtcaaagtct tttggatgag tatgagatga tgattgtgga
     2461 tgagtgtcat catgtctctg ccttgatgtt tgaaaaagtt gttgctcagt ttagagggaa
     2521 gtatctttac ggtttgacgg ctacgcctga gcgtaagaat ggtcatgagc ctattgtttt
     2581 tcagagaatt ggtgagatac tccatactgc tgataagagg gaaacggatt ttaaacggca
     2641 attgcaatta agattcactt cttttggtca tttggagatt gaaaagacca aagcaagtaa
     2701 ttttatacag ctcagtgatt ggattgctac agactcagcg aggaatcagt tgattctcaa
     2761 ggatattcta gcccaagtgg cagaaggacg gaatatcttg gttttagtta atcgaattca
     2821 acagatagat gtctttgaaa agttattgaa agagaaagag gttgatggct gttacattat
     2881 tagcggaaaa accaaagtcc gagaaagaac gagtttactg gagacgttag aacagttaga
     2941 taaagggttt gttttgttgt ctactggaaa atacattggc gaaggttttg acttacctca
     3001 gttggacacg cttatcttgg cagcaccctt ttcttggaaa aataatttaa ttcagtatgc
     3061 aggtcggatt catagaaact acaaggataa gtctttggtg cgtattttcg attatgtgga
     3121 tattcatgtt ccttatttag aaaagatgtt tcagaaacga caagtagctt atcgaaagat
     3181 ggattatcgt gtcatcgagg gtgaggagaa acaattcgtt tatgttgata gtagatatga
     3241 gaaggtgttg agagaggact tagcagggga aagacaggaa tgtctgctta ttttacctta
     3301 tgtgcaccag acaaaactga tgaattttct aaaagaattt aggattagtc aaattgagat
     3361 atgtatacca gagacggttg caaataaagc atggctagac cagttgaaga gccagaaaat
     3421 taaagtgtct tttactcaat caaaaatagt aacgcctatt cttttggtga ataagactat
     3481 tgtttggtat ggtgcaatgc cattattagg gaaggtagat gagatgacca tattacgttt
     3541 ggaatcagct agtatagttt ctgaactagt ggcaggttta cgatagagaa aatttttaaa
     3601 aatttctatg tatgattttc attttttaat gagactgttg acattatcac attcgaagca
     3661 cacaaaataa aaaaatttct acaagtactt gacaaataga ttgaaatatc ttaaaatgaa
     3721 aatggttaca gagttattaa ttatttaagc ttcatgtcac cattaaaaat tgaaataaaa
     3781 ggatgttatc actaatacaa gtgagcagga acctatttaa tcacatcgga agaagtttct
     3841 tgatgttttt aagtaggttc cttttatttt aaaagggaaa ttttatgatc ataaaacgaa
     3901 tactaaacca caatgccgta attgcgcaaa gtaaaaaaga tatcgatatt cttctttttg
     3961 gaaggggaat agcttttgga agaaaaattg gagataaagt aaatccaatt gatattgaga
     4021 aaagtttttt tctcaaaaat agagataata tgacccgttt tacagagatg tttattaacg
     4081 ttcctttgga gttggtgtac atcaccgaaa aaataattaa tctaggtaaa ataacattgg
     4141 ggaataattt tgatgaaatt atctatatta atttaacgga tcatatttct tcgagcatag
     4201 aacgttataa agaagggatt attatttcga atcccctacg ctgggaaatc tcgaaatatt
     4261 ataaagaaga atttgagctt gggaaaaggg ctttacaaat aataaaaaaa gagttaggta
     4321 ttgaacttcc aattgacgaa gctgcattca tagcgctaca ttttgttaat gctaatttag
     4381 aaaataattt tcaagagtcg tataaaatca ctgaaataat tatgggaatt gagaaaatca
     4441 ttcaagattt ctattgtact gagtttaacc aagattctat tgattattat agattcataa
     4501 ctcatataaa attatttgcc catcgcttgg ttgaaaatac aacttattgt gacgatgatg
     4561 atgaagactt gttagcatta atgaaaaata aatatcctag agaatatgaa tgtggtgaac
     4621 aggtggcaat gtttatacaa actgagtaca attatttgct gacttctagt gaattagttt
     4681 atttgatggc tcatattcgt cgcttaacaa aaaatttaga ttaatagaat aggagaatac
     4741 catgagttat aaagataagg tacaaaaaat cctcgatgta attggaggtg aaaaaaatgt
     4801 caatagagtt acccattgtg taacacgttt aagattagaa ttaaaagatg aaaatttagt
     4861 caatgatgat gatgtgaaga agataccagg tgtaataggt attatgaaaa agaatggaca
     4921 atatcaaatt atacttggta atgatgtagc taattattat aaagaattcg ttaaacttgg
     4981 caattttgaa tccgattcag ttgttcaagg gcacaaaggg aatattttag aaagaatcat
     5041 tgagtatatc gctggttcca tgactccaat cattccagca atgttagggg gaggtatgtt
     5101 gaaagtcttg gtaatcattt taccaatgct tggtatattg caatcagatt ctcagactat
     5161 tgcttttttg acattttttg gggatgctcc atattatttc ttaccgctgt tattagctta
     5221 ttctgcatca caaaaattaa aagtaacatc tacattagct atgtctgtag caggtgtact
     5281 tctccatcca aattttgttc aaatggtgca atcagggaat cctcttagtt tatttggtgt
     5341 acctgtgaca ccagctagtt atggttcgtc agtcgttcca attcttatta tggtttggtt
     5401 gatgaaatat attgaaaaaa tgattgctaa attaacacca gctgttacta agagtttttt
     5461 gcaacctacg ctagtattat tagtatcaag ctgtattgcc ttagttgtag tcgggcctat
     5521 tggagtaatt gttggtgaag gattatcaaa tctagttggg caaatgtatg gtgtagctgg
     5581 atggcttaca ttagctattc ttggtgctat tatgccattt attgttatga ctggaatgca
     5641 ttgggctttt gcacctattt ttttggcggc atctattgct actccagacg tattaattct
     5701 tccagcaatg ttagggtcaa acttagctca aggggctgct tcgatggctg ttgcattaaa
     5761 gagtaaaaat aataatacaa aacaaattgc ttttgcagca ggtttctcag ccttacttgc
     5821 agggattacc gaacctgcat tatatggtgt gactttaaaa tataaaaaac cgctttatgc
     5881 agctatgatt ggtggtggat tagcgggatt atttgcaggt cttactagtg ttaaagcgta
     5941 tctatttgct gtcccatctt tgatagcgtt gcctcaattt atttattctg atgtgccatc
     6001 aaatattgta aatgctttaa ttgtggcggt tatttcggtt gttattacct ttgtattagc
     6061 ttatatattt ggaatcgatg aagaagagag ttctagcaat ttagaagtta aagctggagt
     6121 ttcaaataaa aaaatgatat tttctcctat atcaggagaa atcattccgt taagcgatgt
     6181 ccaggataaa acattttcag ataaactaat tggagacgga gtagcgatta ttccaagtga
     6241 aggtaaggtt tatgcaccat ttgatgggaa aattacaaat atttttccga ctaagcacgc
     6301 aattggattg aagagtgatg agggtgttga gttactaatt catattggat tagatactgt
     6361 tgagctaaaa ggtcaaggtt ttattagtca tgtagaagaa ggagacagag ttttcaaaaa
     6421 tcagttgatt tttgaaatgg acttgaattt aatcaagact aaaggctacg aaacagttac
     6481 accagtaatt gtaacgaata ccaatgattt tctagatgta ttagtattac ctaataatca
     6541 gacaatcgag cattctaagg aattactggt aatattataa tggaggaaag ttatgaccat
     6601 ttttccagat gattttcttt ggggtggagc tgttgcagct aatcaagtag agggagcata
     6661 taatgaagat ggtaagggct tatcagttca ggatgtgtta cccaaaggtg gattaggaga
     6721 agcaacagaa aatcctacag aagataactt aaaattgata ggtattgatt tttatcataa
     6781 atataaggaa gatatatcct tgttttctga aatgggcttt aatgtttttc gtacttctat
     6841 tgcatggagt agaatttttc caaaaggaga tgaggaagaa cctaacgaag ctgggttgaa
     6901 atattatgat gaattgtttg atgaactaca tgctcacggg atagaaccac ttgtaactct
     6961 ttcacactat gagactccat tatatttagc aagaaaatat catggatgga ttgataggag
     7021 aatgattcat ttttatgaaa aatttgctcg aacagtttta gaaaggtata aagataaagt
     7081 taaatattgg cttacattta acgaagtaaa ctctgttttg gaattaccgt ttactagtgg
     7141 aggaatagat atacctaagg agaatctttc gaaacaagaa ttatatcaag ctatacatca
     7201 tgaattagtc gcctcgagtt tggttacaaa aattgctcgt gagattaatt cagagtttaa
     7261 ggtggggtgt atggtattag ctatgccagc ttatccaatg actccaaatc caaaagatgt
     7321 atgggcgact catgagtatg agaatctaaa ttatctattt tcagatgtgc atgttagagg
     7381 ttattatccg aattatgcaa aaagatattt taaggaaaat gacattaaca tagagtttgc
     7441 agctgaagat gcagagttat taaaaaatta tactgtagat tttttatcct ttagctatta
     7501 catgagtgtg actcaatctg ctcttccaac acagtataat tcaggagaag ggaatattat
     7561 tggtggttta gtaaatcctt atttagagtc ttctgagtgg ggatggcaaa ttgatccaat
     7621 tggactacgt ataattttaa atagatatta tgaccgttat caaattccat tatttatagt
     7681 ggaaaacgga ttaggtgcta aagatcaact aataaaagat gaatttaata acttaacagt
     7741 ccaagatgat tatagaattc agtatatgaa agaacattta ttgcaagtag ctgaagctct
     7801 acaagatggt gtggaaatta tgggctatac gtcttgggga tgtattgact gcgtttctat
     7861 gtccactgca cagctttcta agaggtacgg tctcatttat gttgatcgaa atgatgatgg
     7921 aaatggcaca ttcaatcgat ataagaaaat gtcctttact tggtataaag gagtgattga
     7981 atcaaatgga gaatccttat tcaaatagtt tgtttattga tgattagata ttatcacggt
     8041 taaggcagca tctcattaaa tatgaaataa agaggtttgg aagacatcaa attctaaacc
     8101 tctttatttt atagggggat taattaattt aattttgtta cagagagccg attataaata
     8161 gttaacttag gatagattgg ttatatatag tagactgaat ctaaaatagt acgaaacaat
     8221 tgctaaaaca tttatagaaa ttaattttac tttcccaatc gatttgtttt catcttattt
     8281 caatccgcta taaagttaga taagaataag ctaacaagca gaagtaagat aggtcttgca
     8341 agaatggtaa aaatctgata aactaagtgg taattgaata gaaatctgaa agactagtag
     8401 cccaagggaa gtatatcagg gaggagagcc gtgactgcaa gctctctata tgaaagctgg
     8461 gtgaattcac ttgcgcatgg atttagaaat gaaggtctga cttgtcagat gaaaacggat
     8521 ggtaccgcgt gtcaacgctc cgagtggagt ttttggcatg tggttttctt tttatctacg
     8581 agagactgat ggaggaaata tgtcaactat tgaagaacaa ttaaaagcgc ttcgcgaaga
     8641 aacgctgact agcttgaagc agattactgc tggaaatgaa aaagagatgc aagatttgcg
     8701 tgtctctgtc cttggtaaaa agggttcgct cactgaaatc ctcaaaggga tgaaagatgt
     8761 ttctgctgag atgcgtccaa tcatcgggaa acacgtcaat gaagctcgtg atgtcttgac
     8821 agctgctttt gaagaaacag ctaagctctt ggaagaaaag aaagtcgcgg ctcaactggc
     8881 tagcgagagt atcgatgtga cgcttccagg tcgtccagtt gcgactggtc accgtcacgt
     8941 tttgacacaa accagtgaag aaatcgaaga tatcttcatc ggtatgggtt atcaagtcgt
     9001 ggatggtttt gaagtggagc aagactacta taactttgaa cgtatgaacc ttccaaaaga
     9061 ccacccagct cgtgatatgc aggatacttt ctatatcact gaagaaatct tgctccgtac
     9121 ccacacgtct ccagttcagg cgcgtgctat ggatgcccat gatttttcta aaggtccttt
     9181 gaagatgatc tcgccagggc gtgtcttccg tcgcgatacg gacgatgcga cccacagtca
     9241 ccaattccac caaatcgaag gcttggtagt tgggaaaaat atctctatgg ctgatcttca
     9301 aggaacgctt cagttgattg tccaaaaaat gtttggtgaa gagcgtcaaa ttcgtttgcg
     9361 tccatcttac ttcccattca cagagccatc tgttgaggtg gatgtttctt gcttcaagtg
     9421 tggtggagaa ggctgtaacg tatgtaagaa aacaggttgg atcgaaatta tgggagccgg
     9481 tatggttcac ccacgtgtcc ttgaaatgag tggtatcgat gcgactgtat actctggttt
     9541 tgcctttggt cttggacaag agcgtgtagc tatgctccgt tatggaatca acgatatccg
     9601 tggattctac caaggagatg tccgcttctc agaacagttt aaataatgat tagaaaagta
     9661 gaaatggcag atgttgaggt gttggctaaa attgccaaac aagcctttcg tgaaaccttt
     9721 gcgtatgata atacggaaga gcagttacag gaatactttg aagaggctta tagtctgaaa
     9781 actttgtcaa ctgagttggg aaatcctgac tctgaaacct atttcattat gcatgaggag
     9841 gagatagctg gttttctcaa agtcaactgg ggaagtgctc aaactgagag agaattagag
     9901 gacgcttttg aaattcaacg cctctatgtg ctacaaaaat tccaagggtt tggactaggt
     9961 aagcaactgt ttgaattcgc acttgaactt gctacaaaaa atagtttttc ttgggcttgg
    10021 ctaggtgttt gggagcataa tacaaaagct caagcgtttt ataatcgata tggttttgaa
    10081 aaatttagcc aacatcattt tatggttggt caaaaagtag atacggattg gttactgaga
    10141 aagaaattaa ggtaagaaga ggattcttct attgaaatga taggaaagga aaagaaccag
    10201 tgtggcaatg gtcattctgg agaactaaat tatgcttata tcttataaat ggttaaaaga
    10261 attggtggac attgatgtgc catcacaaga gttggctgaa aaaatgtcaa ctacaggaat
    10321 cgaggtagag ggtgtcgaat caccagctgc tggtctctca aaaattgtcg tcggtgaggt
    10381 cttgtcttgc gaagatgtgc cagagactca cctccatgtt tgtcaggtta acgttggcga
    10441 agaagagcgt cagatcgttt gcggtgcccc aaatgtgcgt gctgggatca aggtcatggt
    10501 ggctcttcca ggagctcgta tcgctgataa ctacaaaatc aaaaaaggaa aaatccgtgg
    10561 tttggagtca cttggaatga tctgttcact tggtgaattg ggaatttctg actcagttgt
    10621 gcctaaggaa ttcgcagatg gcatccaaat cttgcctgaa gatgccgtgc caggtgagga
    10681 agtcttttct tacctagact tggatgatga aatcatcgaa ctttccatca caccaaaccg
    10741 tgcagatgcc ctttctatgt gtggagtggc tcacgaagtg gcagccatct atgacaaggc
    10801 agtcaacttt aaagaattta ctctaacaga aactaatgaa gctgcggcag atgccctttc
    10861 tgtcagcatt gagacagaca aggcgcctta ctatgcagct cgtatcttgg acaatgtgac
    10921 catcgcacca agtccacaat ggttgcaaaa tcttctcatg aacgaaggaa tccgtcccat
    10981 caataacgta gtggacgtga ccaactacat cctgctctat tttggtcaac caatgcatgc
    11041 ctttgacttg gataactttg aagggactga catccgtgtg cgtgaagcgc gtgctggtga
    11101 aaaattggtg accttggacg gtgaagaacg tgacttggac gtgaatgacc tagtcatcac
    11161 tgtcgcagac aagccagtag cccttgcagg tgtcatgggt ggtcaagcaa cagaaatctc
    11221 tgaaaaatct agtcgtgttg tccttgaagc tgctgttttc aatggcaaat ctatccgtaa
    11281 gacaagtggt cgcctgaacc ttcgttctga gtcatcttct cgctttgaaa aaggaattaa
    11341 tgtggcaaca gttaatgaag cccttgatgc ggtagctagc ctgattgcgg aacttgcagg
    11401 tgcgacggtg cgtaagggca tcgtttcagc gggtgagctt gatacttcag atgtagaagt
    11461 ttcttcaacc cttgctgatg ttaatcgtgt cctcggaact gagctgtctt atgctgatgt
    11521 agaagacgtc ttccgtcgtc ttggctttgg tctttctgga aatgcagaca gctttacagt
    11581 cagagtccca cgtcgtcgtt gggatatcac aatcgaagct gacctctttg aagaaattgc
    11641 tcgtatctat ggttatgacc gcttgccaac tagtctacca aaagacgatg gtacagcagg
    11701 tgaattgaca gccacacaaa aactccgccg tcaagttcgt actattgctg aaggagcagg
    11761 tttgacagaa atcatcacct atactctaac aactcctgaa aaagcagttg agtttacggc
    11821 tcaaccaagt aaccttacgg aactcatgtg gccaatgact gtggatcgtt cagtcctccg
    11881 tcaaaatatg atttcaggta tccttgatac cgttgcctac aacgtggctc gtaagaataa
    11941 aaacttggcc ctttacgaga ttggaaaagt ctttgaacaa acaggtaatc caaaagaaga
    12001 acttccaaat gaaatcaaca gttttgcctt tgccttgaca ggcttggttg ctgaaaaaga
    12061 tttccaaaca gcagcagttc cagttgattt cttctatgct aagggaatcc ttgaagccct
    12121 atttactcgt ttgggactcc aagtaaccta tacagcaaca tctgaaatcg ctagccttca
    12181 tccaggtcgt acagccgtga tttcattcgg tgaccaagtt cttggtttcc ttggccaagt
    12241 gcatccagtc actgccaagg cttacgatat tccagaaacg tatgtggctg agcttaacct
    12301 ttcagctatc gaagctgcgc ttcagccagc gactccattt gtagaaatca ccaaattccc
    12361 ggcagtcagc cgtgacgttg cccttctcct caaggcagaa gtgactcatc aagaagttgt
    12421 agatgctatc caagctgccg gcgtgaaacg tttgacagat atcaaactct ttgacgtctt
    12481 ctcaggtgag aaattgggac ttggtatgaa gtcaatggct tatagcttga ccttccaaaa
    12541 tccagaagat agcttaacgg acgaagaagt cgcacgctat atggaaaaaa tccaagcatc
    12601 gctcgaagaa aaagtcaatg cagaagtgcg ttaaacgata gtatgataca aattccccct
    12661 ctagtttatg aacactagag gggtgatttt atataaaata attaaaatgt gatttctgta
    12721 aaaatacatc tatgatcaga gttttgaaaa cttacaatgt ctaaatcttt aacatagtag
    12781 tggtttttag gcaataaaat atgatctatt gttgcattaa aaagttttgg actttggcta
    12841 ttccaagttc ctctttcaaa aggtggcagt acatttaatg cgtccctatg agagcttatt
    12901 tttgcaagtg ctccatgacg catagttgca ttaaaatcac ctgcaataat agcctttgga
    12961 tattttgaag ccaattgatt atgaatgatg tttaagtctt gcttccagat ttccattaaa
    13021 cctggcagag gaggagcagt atgcaaggca atgatatctg gtatattttg ttttctcgaa
    13081 tgtaatacaa ttgtcccgaa ccgtgttgta tgaaaagttt tagcttctgt atagaaacca
    13141 taacttttct tgacaatcac agtcacagga gctattccac tattggtagg tggagaagtg
    13201 aaaatatcat agttggccat agaaagtcca acttgatgaa acaatagttt gattctctgg
    13261 ttttcttgct cacctctgat attggtagct agttcaggga atatagccat atcggcgtca
    13321 aaatggctaa aaattcgctc aatatgttgt gcttctattt gattagcgac gttccaagtt
    13381 actaatttta aggttttagt cttatttgat gcagaagaaa gggttttatc tgttccgaat
    13441 aatagtaata tgagcgatag taagagcaaa atgccagagt aaaaccgtat ttgtttattt
    13501 ttcttgtaaa aagataggga aaaaaatacg aaacttaaaa tagcagccat agttgcagta
    13561 gctaagggga aggcataaat ctgtgccaag ataggttggg tagatagcca aatgttaaga
    13621 ttagaagatg ggaaaaaaga ataagttata atagggatag aaaagagaat gaccgaaagg
    13681 gcagagagaa atgttttaat cattgtgtga gtacctcaat ttgcaatggt tgctcggagc
    13741 taatgtgact ttgtgacttt acttgattga tattcttttt cttgtcttcc tcatagatta
    13801 agtacaaccc aagtaaaaaa agtccaattt aagattgaaa tgattaaaag gcacagaaat
    13861 gcaagacaat tatactacaa aaggcaaaca tttgacaatc gatagccgtc gcttaatcga
    13921 acgatggaaa aaagaaggaa aatcaaatag agaaattgcc tctctacttg gaaaagctcc
    13981 tcaaactatc catactgaaa tcaagtatgg gacagtccga caatgtcttg gaaaagggcg
    14041 cttcaaagag atttattctg ccgactacgc tcaacagtct tatgaaaata atcgcaagca
    14101 ctcggtcaag aaatcaagct tgactaagaa actaaaggaa aagattctcc actatcataa
    14161 ccaaaaattt tcgcctgaaa tgatggtgat ggctaaaggg gttaacgtgg gaatttcaac
    14221 catttactat tggattcatc gtggaaaatt ggggttaagc aagcaggatc tgctttatcc
    14281 tagaaaagga aaagcgctta agaaataggc tagcaccaac tttaaacccg ctggtcaatc
    14341 tatcgaatca taattcgctc atttttttaa aaatacatag acgtaaaaaa aagagggtta
    14401 agtgatgaag aatagtgcta ttgggagtaa ttggaaggat gtccatctga gctctttagc
    14461 aaggaggaaa tccttgaaag tgatatgcga gtggctatca tgagcgagtt gattgaggct
    14521 aggtatgaac aaggaatcag tcagaaaaag ctggaagaag tcagtggaat aagccagcct
    14581 gtcatagcta ggatggagac aggagagagc agtcttcagt tggatacggt cttaaaagtt
    14641 ctaaccagtc taggaaagac actagcagtc gttccacttg aacaggggaa aagttgacta
    14701 gaatcagtta tagtcttttc taataacagg tcatagtcac ttataagaat tactaataac
    14761 atgttttagt attctaattg gaatatagct gtaaagtaag aattacaaag gatttgagac
    14821 gtttgcttca agtctttttc ttttgtccga aacagatata tagtttcaaa ctatatcaaa
    14881 ccctaatttt ttacaattat acagacgctt tcttttctgt taagatagtt tcaacaacaa
    14941 attttggagg acacatcatg tcaactacaa tcatcggttt ccctcgtttg ggcgaattcc
    15001 gtgaattaaa atttacaact gaaaaatact ttagaaaaga aatctcagaa gaagaacttt
    15061 tagcagcagc aaaagacttg cgtgctaaac actggaacat tgtcaaagaa aaaggcatca
    15121 ctgaaattcc atcaaatgac ttttctcact atgataactt cctagatgcg gctttccttt
    15181 tcaacgtggt gcctgcatcc gttcaaaact tggacttgtc tgaccttgag cgctacttcg
    15241 ctttgggacg tggttaccag ggagaaaaag gggacgttcg cgcccttcca atgaagaaat
    15301 ggttcaacac taactaccac tacatcgttc ctaaatttga aaaagacact caagtaaaat
    15361 tggctggtca caagattttc gatgagttcc aagaagcaaa agaacttgga ttgaacactc
    15421 gtcctgttct tgtaggtcca ttcactttcc ttcaattgtc agactttgaa gaaggcgtga
    15481 aagcagacga cttcgtagat agcttagtgg ttgcttacca agaagttttt gctaaattgg
    15541 ctgaacttgg tgcgactcgc atccaattgg atgaagcggc tcttgtaaaa gacttgacag
    15601 ctgaagaaaa agctctcttc ttgaaccttt acaacaaact cttggctgac aaaaaaggtc
    15661 ttgaagtctt gcttcaaact tatttcggtg atgttcgtga cgtatacgct gaccttgtaa
    15721 acttgccagt agatgctatc ggtcttgact ttgttgaagg taagaaaact cttgaactcg
    15781 ttaaaggtgg cttcccagct gacaagactc tctatgtagg tattgtcaat ggtaaaaaca
    15841 tctggcgcaa caactacgaa aagagcttgg ctgttcttga gcaaatccca gctgaaaaca
    15901 tcgttttgac aagctcttgc tcacttcttc atgtgccatt tacaactgct aatgaagaat
    15961 ttgaaccagc actcttgaac cactttgcct ttgcagttga aaaattggat gaaatccgtg
    16021 acttggatgc tatccgcaat ggtcaaggtt cagaagctct tgcagccaac aaagaactct
    16081 ttgcgactga gcgtgttggt gaaaatgctg aacttcgtgc gcgtatcgct ggcttgacag
    16141 acgcagacta cactcgtttg ccagcctttg cagaacgtga agctatccaa gaagaagctt
    16201 tcaaacttcc agctcttcca acaacaacga ttggttcatt ccctcaaaca aaagaagttc
    16261 gtgccaaacg tttggcttac cgtaaaggtg aattgtctca aaaagagtac gatgctttcc
    16321 ttgctgaaac gattgacgaa tggatcaagt ggcaagaaga tattgacttt gatgtccttg
    16381 ttcacggtga atttgagcgt aatgacatgg ttgagtactt cggtcaaaac ttgtcaggat
    16441 acctcttctc taaaaatgga tgggtacaat catacggtat gcgtggggta aaaccaccaa
    16501 tcatctgggg tgatgtcact cgtcttaacc ctatcactgt taaatggtct agctatgcac
    16561 aaagtcgtac aaacaaacct gttaaaggta tgttgactgg acctgttacc atccttaact
    16621 ggtcattccc acgtgaagac atctctatca aggattcaac tcttcaaatc gcccttgcta
    16681 tcaaggatga agtacttgac cttgaagctg ctggtgtgaa aatcatccaa atcgacgagg
    16741 ctgctcttcg tgaaaaattg ccactccgcc gtagcgactg gtacgaagac taccttgact
    16801 gggctattcc tgccttccgc ttggtacact caacagtagc gccagacaca caaatccaca
    16861 ctcacatgtg ttactcagaa tttacagata tcatcccagc tatcgataac atggatgcag
    16921 acgttatttc ctttgaagct agccgttcaa accttgaaat cttggacgaa ctcaaagcga
    16981 aaaacttcca aacagaagtg ggacctgggg tttacgatat ccactcacct cgtgtaccaa
    17041 atgaaggcga aatcgacaac acaatcgaag ccatccttgc taaagtgcca agcaagaaag
    17101 tttggatcaa ccctgactgt ggtttgaaaa cacgtggtat cccagaaaca aaagaaagct
    17161 tgatccgcct tgttgaagca gctaaagctg cgcgtgagaa attgtaagat tggatttctc
    17221 tccatacagt ggttgttcaa aaagaaatca actagaaaag gttattacat atgtcacgcc
    17281 aaacaccgtc actctcattt gaagtgttcc ctccaaaccc agccgtgggt aatggtaaca
    17341 ttatttcagc cttgcaggat atgcaggagt tggctcccca ttttatcagt gtaactgcca
    17401 gcaataataa atttaatatc aaggaaacga cggttcgttt ggctgacttt atccaaaatg
    17461 acttggcgat tccgaccatt gcccacttgc cagctattta tctaactaag gacaaggttg
    17521 ctgaaactat tgctgacttg gacaaagttg gggtgcagaa aatcttggct cttcgtgggg
    17581 atattattcc agacgtagaa ccacaaaagg atttccgcta tgcaaccgac ttgattgagt
    17641 ttatcaagga acaagcccct cactttgata ttattggagc ttgctatcca gaagggcatc
    17701 cagattcgcc aaatcagatt tcagatattc aaaatcttaa gaagaaagtg gatgcaggct
    17761 gttcgagcct cgtaactcag ctcttctttg ataatgagcg cttctatgat tttcaggaca
    17821 agtgtatttt ggctgggatt gatgttccca ttcatgcagg aattatgcca attctgaatc
    17881 gaaatcaggc tctccgactc ttgaagactt gtgagaatat ccatcttcca cgcaaattta
    17941 aagccatctt agacaagtat gagcatgacc ctgagtcgct cagagcagca ggacttgcct
    18001 atgcagtgga ccaaatcgtg gacttggtaa ctcaggatgt tgccggtgtg catctctata
    18061 cgatgaataa tgctgataca gcaaaataca tccatcaagc aacccatgcc ttgtttaatc
    18121 accagtctct aggataataa aagcaaacca ttcttctcag gtgaggggaa tggttccttt
    18181 ttaatggtaa agacctcact ttttaagaaa aatatgataa aataaattct gtacgtactt
    18241 gatacaaaga tgaaggtatt aaataataca atgcatttaa actgtaagat ttaacgacac
    18301 gagtgagtca aatcgatgtt atttgacgag agagttagta aagcatttag ctaatcgccc
    18361 gatagcgatt agcgtgaaag ctttagatac tttagtatta aacctttcta atgatgtatc
    18421 ttgaaaactg aacttgccta caactctgtg gaaaaagata aatctcccta ggagcagtcg
    18481 ctccgtcgtt cgatttccta ttttcctttg agttgcttga cggcttggta tcttgatgac
    18541 ttgaattttg gtctcatttc ttaggaaaaa agataagctt cctagcactc gtcgagtgcg
    18601 acgtcacctt cctatttttc tacagaaatg ttcggcaagc cgaaccgtcc aaaatatctt
    18661 gtgtaattga acacggccga aaagctgtgt aaaaaagata aactgtcttg tcttcatcga
    18721 agacttcgtc agtttcctat ttttactttg cttttgacgt ccttggtatc ttgatctttg
    18781 taggcaaggc gtataatttc atcaatccaa aggggattaa aatggcaaaa caagtgtttc
    18841 aaacgacttt tgcgggtcgt gagttaattg tagaaactgg tcaggttgct aagcaagcaa
    18901 atggctctgt tgtcgtacgt tacggtgagt caactgtctt gactgctgcc gttatgtcta
    18961 agaaaatggc aactggggat ttcttcccac tccaagtcaa ctacgaagaa aaaatgtatg
    19021 cggctgggaa gtttcctggt ggctttatga aacgtgaagg acgtccttca acagatgcga
    19081 ccttgacagc gcgtttgatt gaccgtccga ttcgtcctat gtttgcggaa ggtttccgta
    19141 atgaagtcca agtcatcaat acagtgcttt cttatgatga aaatgcgtct gcaccaatgg
    19201 ctgctatgtt tggttcatct ttggcactgt ctatttcaga tattccattt gacggaccaa
    19261 ttgctggggt acaagtggga tatgtagatg gccaaatcat catcaaccca agtcaagaac
    19321 aagcagagca atctcttctt gaattgacag tagctggaac caagcacgct atcaacatgg
    19381 tagagtctgg tgctaaagaa ttgtcagaag aaatcatgtt ggaagcgctc cttaaagggc
    19441 acgaagctgt caaagaattg attgccttcc aagaagaaat cgttgctgct gtcggtaaag
    19501 aaaaagcaga agtggaattg cttcacgtgg atgctgaatt gcaagctgaa atcattgcag
    19561 cctacaacag tgacctccaa aaggcagttc aagtagaaga gaaattggcc cgtgaagctg
    19621 cgactcaagt agtgaaagac caagtgactg ccgtttacga agaaaaatat gcggaccacg
    19681 aagaatttga ccgtattatg cgtgatgtgg ctgaaatctt ggaacaaatg gaacacgcag
    19741 aagtgcgacg tttaattaca gaagacaagg tgcgtcctga tggtcgtaag gtcgatgaaa
    19801 tccgtccttt ggatgcggtt gtcgacttcc ttcctcgtgt gcacggttca ggtctcttca
    19861 ctcgtggaca aacgcaagcc ctttctgtct tgaccttggc tccgatggga gaaactcaaa
    19921 tcattgatgg tttggatctg gagtacaaga aacgctttat gcaccactat aacttccctc
    19981 aatattctgt aggggaaaca ggtcgttacg gtgcgccagg tcgtcgtgaa atcggtcacg
    20041 gtgcccttgg tgagcgtgct cttgctcaag tcttgccaag cttggaagaa ttcccatacg
    20101 ctatccgtct agtagcagaa gttttggaat caaacggttc ttcatctcaa gcttctatct
    20161 gtgcgggaac tcttgccctt atggctggtg gtgtgccaat caaggcgcca gtagctggta
    20221 ttgctatggg acttatctca gatggaaata actacacagt attgacagat atccaaggtt
    20281 tggaagatca ctttggagat atggacttca aggttgcagg tactcgtgat gggattacag
    20341 cccttcaaat ggatatcaag attcaaggga ttactgcaga aatcttgacg gaggctcttg
    20401 ctcaagccaa gaaagcgcgt tttgaaatcc ttgatgtcat tgaagcaacc attccagaag
    20461 ttcgtccaga attggctcca actgctccga aaattgatac gatcaagatt gatgtggaca
    20521 agattaagat tgtcatcggt aagggtggag aaaccatcga caagattatc gctgaaacag
    20581 gtgttaagat tgatatagac gaagaaggaa atgtgtctat ctactctagt gaccaagatg
    20641 ctattaaccg tgccaaagaa attattgctg gtttggttcg tgaagccaaa gtggatgaag
    20701 tttaccgtgc taaagtcgtt cgtatcgaga aatttggtgc ctttgttaac ctctttgata
    20761 agacagatgc ccttgttcat atctctgaga tggcttggac tcgtaccaat cgtgtagagg
    20821 atttggtaga aatcggggat gaagttgatg ttaaggttat caaaattgat gaaaaaggcc
    20881 gtatcgatgc ctctatgaag gctcttctac ctcgtccgcc aaaacctgag catgatgaaa
    20941 aaggtgaaaa gtctgagcgc cctcaccgcc cacgtcatca aaaggatcac aaacctaaga
    21001 aagaatttac agaaacacca aaagattcag aataagaaaa ggagaaatgt atggggtggt
    21061 ggcgcgaaac cattgatatt gtaaaagaaa atgatccagc ggcccgcacc actttggagg
    21121 ttttgctgac ttatccaggt gtcaaggcct tggcggccca ccgtctctcg cattttctct
    21181 ggaagcacgg cttcaaacta ttagctcgta tgtacagtca gttttggcgc ttttggactc
    21241 agattgagat tcatccagga gcccagattg attcaggtgt ttttattgac catggttctg
    21301 gtctggtgat tggagagaca gcgattgttg aaaaaggcgt tcttctctat cacggagtga
    21361 ctctcggggg aacagggaaa gactgtggca aacgccatcc gactgtacga aagggagccc
    21421 tcatatcagc ccatgcccaa gttatcgggc ctgtggaaat tggtgaaaat gccaaggtcg
    21481 gtgctgcagc agttgtcgta gcagatgtac ctagtgatgt gacggttgtc ggtattccgg
    21541 ccaagattgt ccgtcttcat ggtaagaaag atgagcctgt tattcacgaa gtcgaagaaa
    21601 aacgggagta ttatgtcaat aaactcgagc aggctaaaga tgccagtcac agatcgtctg
    21661 gtttgtagag gatacctata tgattcaagc aagaaacaag ttaagccaag aggagctatc
    21721 tgaggcgaaa aaagtaatta actgttgcca aaactatgac ggtacctatc gcgatcccta
    21781 tctctctaac atgcttaatt ttgacccaaa catgcccgcc tttttccttt attatgaaaa
    21841 aggcaaactt gttggtttat taactgtcta tgcagatgac caagatgtag aagtgacgat
    21901 attggttcat ccaggtcatc gccgtcaggg gattgcgcgt gcattgttta ctagttttga
    21961 gagagaaaca gcttctttcc ccattcggtc agtcactttt cagacagaac gtattttttt
    22021 agagaatcat cctgactttg ccagtaactg gggactaatc gaggatgaag agacagaaac
    22081 ttggttaggt aaggatagaa gaccttatcc gttagcaaat gtttcccatc ttgaagtttt
    22141 gttagcagat agttcgtatc aggatcaaat tagtcaatta aaatttcagg cattttcaga
    22201 ggaacatgaa tcgagagaag ttgtggatag atatgtcgct gaagctctga aggatccaga
    22261 aagtcgctta tatattttgt taaaagacgg tcaggttatt gggacttgca cggtagattt
    22321 atcgactaat acgaattact tctacggttt agcaatatcg gaacctgaac gtgggaaagg
    22381 ctatggaagc tacttagcaa aatccctcgt caaccaacta attgagcaaa atgacaagga
    22441 atttcagatt gcagtggaag atagcaatgt aggtgccaaa cgtttgtatg aaaaaattgg
    22501 ctttgtcaaa cagacacagg tggtttatct gaatgagaaa ggagcaaggg attccgaagt
    22561 gtagagacat tcggactgaa atttacttga gctcttagtt tagtgatgaa actaacagtt
    22621 cttggatttt agctttcctg attatgattt atgattaaaa tctatgacac catgtctcgt
    22681 gatttgcgag aatttgtccc gattgaggac ggcaagatca agatgtatgt ttgtgggcca
    22741 accgtgtaca actatattca cgtgggaaac gcccgttcga cggtagcttt tgatacgatt
    22801 cgtcgctatt ttgagtaccg tgggtataag gttgcctata tttccaattt tacagatgtg
    22861 gatgataaga ttatcaaccg tgccagggaa gaaggcatca cacctcagga ggttgcggat
    22921 aagtacatcg ctgcctttcg tgaggatgtg acggccttag gcgtgaaacc tgcgactcgc
    22981 catccgcgtg tagtggagtt tatggcagac atcatccgtt ttgtggaaga cttgatcgag
    23041 aaaggctttg cctatgagag tcaaggggat gtctatttcc gtgtagaaaa atcccacaac
    23101 tatgctaaat tggctaataa aaccttggaa gatttggagc taggtgcttc aggtcgtacc
    23161 gatgaagaaa cggctcgtaa ggaaaatcct gtagactttg ctctatggaa atcttccaaa
    23221 ccaggtgaga tttcttggga tagtccttgg ggacctggac gtccgggttg gcatattgag
    23281 tgttcagtca tgtcgacaga gattttaggt gataccattg atatccacgg tggtggagct
    23341 gacctagagt ttccacacca caccaatgaa attgcccaat ctgaagctaa aacaggcaag
    23401 gcttttgcta actactggat gcacaatggc tttgtcaata tcgacaatgt caaaatgtct
    23461 aagtccttgg gtaacttcat tacggtacac gatgccctta aaactcttga tgggcaagta
    23521 cttcgtttct tctttgcgac ccagcactac cgtaagccta tcaacttcac ggaaaaggca
    23581 gttcgcgatg ccgagaccaa tctcaagtat ctgaagaata cttacgaaca accatttaca
    23641 ggaaacgtgg atgcccaaga gttacaaaac tttaaagata agtttgtagc agctatggat
    23701 gaagatttta atgctgccaa cggtatcaca gttgtctttg aaatggccaa atggatcaac
    23761 tcagggaact atgatgcaag tgtcaagcaa gctcttgcag atatgttaga aatttttgga
    23821 attgtctttg ttgaggaagt tttggatgca gagattgaag acttgattca aaaacgccaa
    23881 gaggcgcgtg ccaatcgtga ctttgagaca gcagaccaaa tccgtgacca attggttact
    23941 caaggaatta agctccttga taccaaggat ggagtgaggt ggacacgtga ttgatgtcaa
    24001 tctcattaac gggattgcgc tagcctttga gggagatgcg gtgtattcta tgtatattcg
    24061 ccgccacctc atcctcaaag gtatgaccaa gcccaataaa ctccaccaag aggcgaccaa
    24121 gtacgtgtca gccaaggctc aggctcgtct gattgctctc atgttggagg agcagatcct
    24181 aacggaaaaa gaagaagaaa tctacaaacg tggccgcaat accaatagtc acacaaaggc
    24241 taaaaatgca gatgtcgtga cttatcgtat gtccacggga tttgaagcag ttatgggcta
    24301 tctccatatg actgagaatc tggaacgtct tgagagtttg gtttcatggt gcatccaaaa
    24361 agtggagggc tagaacatga gggcaaaaga actacaagac tggtttcctg aggctcggat
    24421 ttcagaccaa ccagtagaga aagagggcta tctcacgctt cctttagctt ctcagcagtg
    24481 gattttgctg gaggaagctg ggctcagcga gcgtgaaaag cagttggttg cccttttgac
    24541 ccagcaggag caggctcgtt cgctaaaccc ttggtattcc tatctggttg agggcaaggg
    24601 acaggcaccg caagttttta aaaagattca gttggtttat tgccatcttt cttattttca
    24661 gcaggaaaat ctgacttctt ggctagatat gatgcggact ctttttccga attgtcagac
    24721 agtgctacag gtcggagctc aggattatgt tttcgtgctt caacaagaca aatacacttc
    24781 tgtaagagat attttgagtg atacgattga agcggttgag tatgactttg gacttcgtct
    24841 ttctatcatg ttgggtcagg tttggtctca gacaggacat caagccctat cagacttaat
    24901 caaagctgag cgggatttgt tcaagacatg gtggcgtcag ggtcaccaag gtgttcatac
    24961 tttttctcag ctctatcttt ggagtatggg agaaagactc gtggacttga agccaattaa
    25021 agaatgtcta caccagatga ttttggatca agatcagatt caggaaatca ttctctctct
    25081 ttgggaaaat agtgctgttc tcactaaaac agcccagcaa ctctatctgc accgcaattc
    25141 tctccaatac aagattgata aatgggaaga gttgacaggg cttcagttga aagagttgac
    25201 cgacctgacc ttgtgttatc aattgatttt aggttttttg tcaactatag ttggtttgta
    25261 aagaagttaa t
//
LOCUS       DBERCW010000030        24430 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.030, whole genome shotgun sequence.
ACCESSION   DBERCW010000030 DBERCW010000000
VERSION     DBERCW010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.030"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..156
                     /locus_tag="ACL72M_001506"
     CDS             <1..156
                     /locus_tag="ACL72M_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716616.1"
                     /translation="CTQIIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLMDLGGEYY
                     SLYTKRK"
     gene            169..339
                     /locus_tag="ACL72M_001507"
     CDS             169..339
                     /locus_tag="ACL72M_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716617.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYAISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            373..1101
                     /locus_tag="ACL72M_001508"
     CDS             373..1101
                     /locus_tag="ACL72M_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716618.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            1094..1831
                     /locus_tag="ACL72M_001509"
     CDS             1094..1831
                     /locus_tag="ACL72M_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716619.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNVLLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            1844..2554
                     /locus_tag="ACL72M_001510"
     CDS             1844..2554
                     /locus_tag="ACL72M_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716620.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISALYSE
                     LDYNKYWYILHTLIYMLMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVCIWIMG
                     FEFFLLPKLIKLKEQNLV"
     gene            3096..3317
                     /locus_tag="ACL72M_001511"
     CDS             3096..3317
                     /locus_tag="ACL72M_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0716621.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            3763..4087
                     /locus_tag="ACL72M_001512"
                     /pseudo
     CDS             3763..4087
                     /locus_tag="ACL72M_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            4215..5444
                     /locus_tag="ACL72M_001513"
     CDS             4215..5444
                     /locus_tag="ACL72M_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS0716622.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5464..8160
                     /gene="ppc"
                     /locus_tag="ACL72M_001514"
     CDS             5464..8160
                     /gene="ppc"
                     /locus_tag="ACL72M_001514"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGS0716623.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    8243..8460
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8573..9577
                     /gene="trpX"
                     /locus_tag="ACL72M_001515"
     CDS             8573..9577
                     /gene="trpX"
                     /locus_tag="ACL72M_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0716624.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            9646..10512
                     /locus_tag="ACL72M_001516"
     CDS             9646..10512
                     /locus_tag="ACL72M_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716625.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10509..11267
                     /locus_tag="ACL72M_001517"
     CDS             10509..11267
                     /locus_tag="ACL72M_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716626.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            11357..13117
                     /gene="dnaG"
                     /locus_tag="ACL72M_001518"
     CDS             11357..13117
                     /gene="dnaG"
                     /locus_tag="ACL72M_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGS0716627.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            13120..14229
                     /gene="rpoD"
                     /locus_tag="ACL72M_001519"
     CDS             13120..14229
                     /gene="rpoD"
                     /locus_tag="ACL72M_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGS0716628.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            14243..14572
                     /locus_tag="ACL72M_001520"
     CDS             14243..14572
                     /locus_tag="ACL72M_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS0716629.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            14687..15730
                     /gene="cpoA"
                     /locus_tag="ACL72M_001521"
     CDS             14687..15730
                     /gene="cpoA"
                     /locus_tag="ACL72M_001521"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGS0716630.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            15746..17071
                     /locus_tag="ACL72M_001522"
     CDS             15746..17071
                     /locus_tag="ACL72M_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0716631.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            17102..17278
                     /locus_tag="ACL72M_001523"
     CDS             17102..17278
                     /locus_tag="ACL72M_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS0716632.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            17337..17471
                     /locus_tag="ACL72M_001524"
     CDS             17337..17471
                     /locus_tag="ACL72M_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGS0716633.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            17535..18845
                     /gene="obgE"
                     /locus_tag="ACL72M_001525"
     CDS             17535..18845
                     /gene="obgE"
                     /locus_tag="ACL72M_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGS0716634.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            18855..19013
                     /locus_tag="ACL72M_001526"
     CDS             18855..19013
                     /locus_tag="ACL72M_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716635.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            20100..21359
                     /locus_tag="ACL72M_001527"
     CDS             20100..21359
                     /locus_tag="ACL72M_001527"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS0716636.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            21375..21926
                     /locus_tag="ACL72M_001528"
     CDS             21375..21926
                     /locus_tag="ACL72M_001528"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716637.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            21919..23196
                     /gene="spxR"
                     /locus_tag="ACL72M_001529"
     CDS             21919..23196
                     /gene="spxR"
                     /locus_tag="ACL72M_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGS0716638.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFWVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            23212..24072
                     /locus_tag="ACL72M_001530"
     CDS             23212..24072
                     /locus_tag="ACL72M_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGS0716639.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            24297..>24430
                     /locus_tag="ACL72M_001531"
     CDS             24297..>24430
                     /locus_tag="ACL72M_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGS0716640.1"
                     /translation="MSQSIVPVEIPQYCRFDSKKRNGILFNVRIANLKFTFFRLDFLR
                     "
BASE COUNT         7604 a         4028 c         5278 g         7520 t
ORIGIN      
        1 tgtactcaaa taattatagc tcatagattg tcaacgatta aggatgcgga tattattttt
       61 gtaatgaaag gtggtaagat tgttgagtca ggaaatcata agtacttaat ggatcttggt
      121 ggagagtact acagcttata tacaaaaagg aaatgaggtg taaagaaaat gaagaaagta
      181 aatgaatatg taatttcaac agcagcctca ctaggggtga tgattggaat agtatttgca
      241 atttttttag attttccagt tgaatatgct atttctttag gtttgttgaa tggaatagta
      301 ttgggttcgc tgatttttta caaaaacaat aagaattaag cataattttt tgctgtaaac
      361 taaggagtag agatggctat agttgaaatt ataaatctaa caaaaagctt taaagatatt
      421 gaagttattc ataacacttc attttattta aataagggaa aagtatatgg ttttgttgga
      481 ccaaatgggg ctggaaaaac tacaattatc aaaatgattc tagggatttt aaaaccagat
      541 tctgggaaaa taactatttt taatcaaacc gtagaacaga attccgaaaa tatattatct
      601 aggataggat tagttttggg accttcattt tatggtcatc ttgatgctta taaaaatttg
      661 aagttaatag caaatatgaa agggcttagt ttagatactg aaagacttaa tgaatatcta
      721 tcaatggtag gattaaaaga tgttaaaaag aaaaaagtga aaaatttttc aatgggcatg
      781 aaacaacgtc taagtatagc tgcatcattg ttaggtagtc cagaaatatt aatttgggat
      841 gaaccaatca atggacttga tccacagggt gtaattgaaa ttagaagttt aatccgtttt
      901 ctacaggaga aaaaaggtat tacattttta atatcaagtc atattcttag tgaactggat
      961 aaagtgatat ctgatattat aattataaat tatgggaaag ttgaattttt tggttcttgc
     1021 cactaccttt tacaaaagta taattgtcga aatctggaag aagcctactt agcttgttta
     1081 gctggaggtg aatatgatta aattagagtt tctaaagcag aaaaaaagca tcttatggtt
     1141 tgttcttatt tttccaataa ttctgaatgt tttgttatat atagacttaa cttttaggta
     1201 tcgaggttat ttattggtgc atcaaaatga acttgcttta tctaattggc agttaatttt
     1261 taaagaacaa acaatatttt atttttctga actattttat ttagttctat ctttaataat
     1321 ttacgaagtg tttgcagtag aatttaaaaa tgatgcatgg ttaaccgtaa tttcattgcc
     1381 atttagaaac aagtacacaa taaattctaa attactcatt acagtggttt acacatttac
     1441 tttttggttg tctgattata ttagcttata cgttattggg aaggctattg ataacagttt
     1501 agagattggt ttgattttct ttttaaaaac atttaccatt caattaattt cctcgttgat
     1561 gataatgtta ttatattttc taactttagt acttataagg aaaatttctg gaataatacc
     1621 aattggtatt ataatgatga ttttaacaat tagcatatac tacaacgatt ataattttaa
     1681 gatttactta ccatttactt atctttctca tgcttttaga gtgactgaaa gtcaatttta
     1741 tatgatttta ctatctaata taataatcat cgtacttttt tatatattaa ttcgtaaatt
     1801 gaacgaaaga agttttgaga tgaaacttta ataggtaata aaaatgaagt tacttaaaaa
     1861 tgaattgatt aagagtaaaa tatttttatt tattattgtt gacatctgta ttcagattct
     1921 agtcattcta gctataaaaa catatatttt agatatttcg gcactatact cagagcttga
     1981 ttataataag tattggtata ttttacacac tttaatatat atgctaatga tttttcctat
     2041 acaaattttg tatcaaaatc taagagaggc attgattgaa gataataata atggttggaa
     2101 tatcatggtg attaacacta ataatctcgt gaaaatcatc tatataaaag taacgataaa
     2161 tatcgtgaga tgttttattt gttattttgt ttatacaatt ttttctttaa ttcaattagg
     2221 tggtatggga actgatatgt tattaaccaa tataatattt cccaatataa tgtcatttct
     2281 tttattttta cctatagcta tctttatgca aatttgctgt ataagatttg attccatttt
     2341 agcaaaggcc ttacctaata ttttgctgat acttattgtt ttaatcacgt ttcagagtga
     2401 ttggaatata tttatacctg caacttatta ttatacagaa attcagtcaa ctacaaactt
     2461 aggtattaaa ttattagttt gtatctggat tatgggattt gaatttttcc ttcttccaaa
     2521 actaataaaa ttgaaagaac aaaatctagt ttaaatgttg ctcgaaaatt aaataattga
     2581 atacgattaa caatgaaaca atacaacgtg agtcatgact tcaaagtaat tgattttatg
     2641 attctggttt cttacgctta attaagcaag ttgtattcac tttatcaaat tgttattact
     2701 ctaaaaagcg tctaacagct atagagtgtc tgtttgcttc tctttacttt tattttaaat
     2761 aattcattaa ccttccgtaa gtgcccaata ataaggtgtg ttgaagaagt ctgagataaa
     2821 atagttctca gtcacaaaaa agctatagat tcccattggt gaacagctcc ctgtcaagta
     2881 gacagtaaaa taatataaaa tcttaagcga cctgattcct gaattccagt ggagtcaggt
     2941 tgttttttaa ccgtctttct taatattgtc ttacctataa tagatatgct tatgagatat
     3001 gtttaataaa ttaattttag ttcaaaatgt ccagttagga cactttgaat gatttcttag
     3061 ttttatatat tatacttttc tcaggagaaa gctagatgta cagacgtttg agagatttga
     3121 gggaagatca cgatttgacc caaaaacaaa tagctaaaat actttcgttt acaaactcag
     3181 cttatgctaa aattgaacgg ggtgagcata cgttaacagc agatgtattg gtaactctct
     3241 caaactttta cgatgtcagt acagactacc tattggaatt gacagatttt cctgataaaa
     3301 ttcgctttag aaaataatct cctcaatttc atagagtgtg aaaatgagga gattttttat
     3361 ttgttctttg aaaattaaat agtccaaaat ggtactttcc tcatttgtgg agcaaatttg
     3421 aatggctcgc catgataaga gcgattttaa aaccatcaat aaaatagagc gatactttat
     3481 atgccatgat acaaatgata tacaatgata cttctgaccg ttcaggctgc catcgtaaaa
     3541 gagcagcaag tgaaattctt atgatgactt catcagtcat gccacgttaa atgtgtgagt
     3601 ttgttagaga aacgcaatta atcctcaaaa ggttccccga accttttgag ttccacagac
     3661 gcatcacgtg gagtgtgtaa gcttgttgct aaaagcgtaa aaaccttgga acgaaaggaa
     3721 taatagactt cctgcgaaac aaaaatacaa tacaataaaa ctatggatga tgaagcaagt
     3781 aaacaattaa gcgatagccg tttcaagagc cttgtaggtg ttcagcgcac gagatgttag
     3841 ctgtgttaaa aacagcttat caacgcaacg taaacgcgca aaaggtggac gaaaaaccaa
     3901 attaagccta gacgatctcc tcatggtaac tattcaatac atgcgagaat agcgcactta
     3961 tgaacaaatt gcggctgatt ttggcattca cgaaagcaac ttaatccgtc ggagccaatg
     4021 ggttgaagta actcttgttc aaaatggttt tacgatttca aattctgccc taattatgaa
     4081 aaacagtaaa attcgaagga ttgtaaggta agagtttttt tctttctgaa aaaatggtat
     4141 aatagcaatc aaaactagaa aataaaacgg aatttggaac agatttgtct gtatcctagt
     4201 agagtggtga tgctatgaag attagtaaga ggcacttatt aaattattcc atcttgattc
     4261 cctacttgct tttatctatt ttgggcttga ttgtggtcta ttcgaccacc agtgctattt
     4321 taattgaaga aggcaagagc gccttgcagt tggttcgaaa ccaaggaatc ttttggattg
     4381 ttagtttgat actgattgcc ttaatttata aattgagact agattttttg agaaatgagc
     4441 gactaatcat tttagttata ttaatagaaa tgcttttatt gttcttggct cgttttattg
     4501 gtatttccgt aaacggggca tacggttgga tttcggttgc aggagtaact attcagccag
     4561 ctgagtactt aaaaatcatt attatttggt atttagctca ccgattctcc aaacagcaag
     4621 aagaaatagc tacttatgat tttcaagttt tgactcaaaa tcaatggctt ccccgtgctt
     4681 ttaatgattg gcgattcgtt ctcctagttc tgattggaag tttgggaatt ttccctgatt
     4741 taggaaatgc gactatttta gtcttggttt ccttgattat gtatacagtt agtggaatcg
     4801 cttatcgctg gttttcaacc attctggcgc tcgtatctgc cgcttctgtc tttgtcttga
     4861 ccactatcag cctaatcggt gttgagacct tttcaaaaat tccagtattt ggctatgtag
     4921 ccaagcgctt tagtgccttt tttaatcctt ttgccgatcg tgctgatgca ggtcaccagt
     4981 tagctaattc ttattttgcc atggtcaatg gtggttggtt tggtctaggt cttggaaact
     5041 cgattgaaaa acgaggttat ttgccagaag ctcatacaga ctttgtcttt tctatcgtga
     5101 ttgaagaatt tggctttgct ggtgccagtc ttattttagc tctcttgttt ttcatgattt
     5161 tgcggattat cttggtcggt attcgagcgg agaatccttt caatgccatg gttgcactcg
     5221 gtgtcggagg gatgatgttg gttcaggtat ttgtcaatat cggagggatt tcgggcttga
     5281 ttccatctac aggagtaacc ttccccttct tatcccaggg tggaaatagt cttctagtct
     5341 tatcagtggc agtagccttt gtcttaaata ttgatgccag tgaaaaacgc gctaagttgt
     5401 accgagaatt ggaaaatcaa ccaatgaacc ttctgttgaa gtaggataaa gaaaggatag
     5461 tttatgtctc ttcaaaaatt agaaaattat agtaataaaa gtgttgtgca agaagaagtc
     5521 ttgattctaa cagaattact ggaagatatt actaaaaata tgcttgcccc agagaccttt
     5581 gaaaaaataa tacagttgaa agaattatca acgcaggaag attatcaagg tctaaaccgt
     5641 ctagtgacta gcttatcaaa tgatgaaatg gtctatattt cacgctattt ctctatctta
     5701 cctcttttga tcaatatttc agaggatgtg gatttagctt atgaaatcaa tcatcaaaat
     5761 aatattgatc aggactattt aggtaaatta tctacaacga ttaaattggt agcagaaaag
     5821 gaaaatgccg ttgagatcct agaacacttg aatgttgtcc ctgttttgac agcccatcca
     5881 acacaagtgc aacgcaaaag tatgttggat ttaacaaatc atattcatag tcttttgcgt
     5941 aaataccgtg atgttaagtt ggggttgatc aataaagata aatggtacaa tgatttgcgt
     6001 cgttacatcg aaattatcat gcagacagac atgattcgtg agaaaaaatt aaaagtgact
     6061 aacgaaatca cgaatgctat ggaatattat aacagctcct ttttgaaagc tgtacctcat
     6121 ttgacgacgg agtataagcg cttagcgcaa gcgcatggtc tgaatttaaa acaggctaaa
     6181 ccaatcacca tgggtatgtg gataggtggt gaccgtgatg gaaatccatt tgttacagca
     6241 gagaccttga agcagtctgc actcactcaa tgtgaagtca tcatgaacta ctatgataaa
     6301 aagatttacc aactttatcg tgaattttct ctttcaacta gcattgtcaa cgtcagcaag
     6361 caagtcagag aaatggctcg tcaatccaag gataactcga tttaccgcga aaaagagctt
     6421 taccgtcgtg ccttgtttga tattcaatca aaaattcagg caactaaaac ctatctgatt
     6481 gaggatgaag aagttgggac tcgttatgaa accgccaatg atttctacaa ggatttgatt
     6541 gccattcgag attctctact agaaaataag ggtgagtcct tgatttcagg tgattttgtg
     6601 gaattattgc aggcagtaga gatatttggt ttttacctag catcaattga tatgcgacaa
     6661 gactctagcg tctatgaagc ctgtgtggca gaactcttga aatcagcagg aattcattct
     6721 cgttatagcg agttgagcga agaagaaaag tgtgaccttc tcttgaaaga attagaagaa
     6781 gatccccgaa ttctttctgc gactcacgca gaaaaatcag aattattagc aaaagaatta
     6841 gctattttta agacggctcg tgttttgaaa gataagttgg gagatgatgt catccgtcag
     6901 accatcattt cacatgcaac cagcctttct gatatgctag aattagctat tctgttaaaa
     6961 gaagtaggac tggtggatac ggaaagggcg cgtgttcaga ttgttcccct ttttgaaaca
     7021 attgaagact tggatcattc agaagaaaca atgagaaaat atctttctct tagccttgcc
     7081 aaaaaatgga ttgactcacg aaataactac caagaaatca tgcttggcta ctctgacagt
     7141 aataaagatg gcggttactt gtcatcatgt tggaccctct acaaggctca acaacaattg
     7201 actgctattg gagatgaatt tggcgttaag gttaccttct tccatggtcg tggtggtact
     7261 gtcggtcgtg gtggtgggcc aacctatgaa gccattacat ctcaaccgct caagtctatc
     7321 aaggatcgta tccgcttgac ggagcagggt gaagtaattg ggaataaata cggtaacaaa
     7381 gacgccgctt actataacct tgaaatgcta gtatcggcag ctattaaccg tatgattact
     7441 cagaagaaga gcgataccaa taccccaaat cgttatgaag ccattatgga tcaagtagtg
     7501 gaccgtagtt acgatatcta ccgtgatttg gtctttggta atgagcattt ctatgattat
     7561 ttcttcgagt caagtccaat caaggctatt tcaagtttta atattggttc tcgtccagcc
     7621 gctcgtaaga ctattactga aatcggtggt ttgcgtgcca tcccttgggt attctcatgg
     7681 tcacagagtc gtgttatgtt ccctggatgg tacggggttg gttcaagctt caaggaattt
     7741 atcaataaaa atccagagaa tattgctatc ttacgagata tgtaccaaaa ttggcctttc
     7801 ttccaatcgc ttctttcaaa tgttgatatg gttttgtcaa aatcaaatat gaatattgct
     7861 tttgaatatg ctaaactttg tgaagacgag caagttaagg ccatctatga gactatttta
     7921 aatgaatggc aagttactaa gaacgttatc ttggctattg aaggacatga cgaactctta
     7981 gctgacaatc catatctaaa agctagtctg gattaccgta tgccttactt taatattctc
     8041 aactatattc agttagagtt gattaaacgc caacgtcgtg gagaattgtc cagtgatcaa
     8101 gaacgattga ttcatatcac catcaacgga attgcgacag gattgcgtaa ttcaggttga
     8161 taattttcaa gagtgaatgc taaaagtgaa tatcaaaaaa attctaatag actattgaca
     8221 agtagtttaa aaatgatata atttaaccat tcagaaaagt aatcatacaa actttttaga
     8281 gagtctgtgg tagctgaaaa cagataagtg gcgatgatga aaattgggct gaatgctatt
     8341 tagaatttga aattataaaa attcggtaag cacaccttac agtgcatctc gttattgcga
     8401 gactgagcga tagggaaatt ccctataatt gaggtggtac cgcgcatcga cgtcctcaca
     8461 caagtttttt gtgtgaggat ttttttgatg gaggttagta tggaaagaaa acgatggcgt
     8521 cgcttgttta gataagtgaa atatgttaaa ggaaataaaa aggagaaaca gaatgaaaaa
     8581 taaacgttta attggaatta ttgctgcatt agcagtctta gtagcaggaa gcttgattta
     8641 ttcttcaatg aataaatcag aagctcagaa taataaggat gagaagaaaa taactaagat
     8701 tggtgtgctt caatttgtga gccatccatc ccttgatttg atttataaag ggatccaaga
     8761 tggacttgca gaagaaggat ataaagatga tcaagttaaa attgatttta tgaactcaga
     8821 aggtgaccaa agtaaggttg cgacaatgag taaacaattg gttgcaaatg ggaatgacct
     8881 tgtggttggt atcgcaacac cagcagccca agggttggct agtgcaacaa aagacctacc
     8941 ggttatcatg gccgctatta cagacccaat tggtgctaac ttggttaaag atttgaaaaa
     9001 accaggtggc aacattacag gggtatctga ccacaatcca gctcaacaac aagttgaact
     9061 catcaaggct ctgacaccga atgtgaaaac aatcggagct ctttactcaa gtagcgaaga
     9121 caattcaaaa acacaggtcg aagaatttaa ggcttatgct gaaaaagcag gtctgacagt
     9181 ggaaacattt gcagttcctt caacaaatga aattgcctca actgtcactg ttatgactag
     9241 caaggtagat gctatttggg ttccaattga taacaccatt gcatcaggat ttccaacggt
     9301 tgtctctagc aatcaaagtt ctaagaaacc aatttatccc agtgcgacag ctatggtaga
     9361 agtaggtggt ttggcatcag ttgtaattga ccaacatgac cttggtgtgg caacaggtaa
     9421 aatgattgtg caagtcttga aaggtgcaaa accagccgat accccagtca atgtcttttc
     9481 aactggtaag tcagtcatca ataaaaaaat agcacaagaa ctaggtatta ctattcctga
     9541 gtctgttctc aaagaagcag gacaagtcat cgaataaata aggtagggag gaggagactc
     9601 ttcccatttt ttaaaaagat gaatatagaa aggattaaat aaaatatgat tgtttccatt
     9661 atttctcaag gatttgtctg ggctattcta ggtctgggaa tctttatgac atttaggatt
     9721 ttaaactttc cagatatgac gacagaaggt tccttccctc ttgggggagc tgttgctgtc
     9781 actttgataa ccaaaggcgt gaacccattt ttagcgacac ttgttgctgt aggagcaggt
     9841 tgtttggctg gaatggcagc aggccttctt tatacaaaag ggaagatccc aaccttgcta
     9901 tcagggattt tggtgatgac ttcttgtcac tcaatcatgc tcttgattat gggacgtgcg
     9961 aatttaggcc tgcttggaac caagcaaatt caggatgttt tgccttttga ttcggatttg
    10021 aatcaactct tgacaggtct catctttgtg agtattgtta ttgctctcat gctctttttc
    10081 ttggacacta aactcggaca agcctatatt gctacagggg ataatcctga tatggctaga
    10141 agtttcggga ttcatactgg acgcatggag ctcatgggct tggtcttatc aaatggtgtg
    10201 attgcccttg caggtgccct cattgctcag caagaaggtt atgccgatgt gtctcgaggg
    10261 atcggggtta tcgttgtggg gcttgcaagt ttgattattg gagaagttat tttcaagagt
    10321 ttgagcttgg cagagcgttt ggttactatc gttgtaggtt ctatcgctta tcaattttta
    10381 gtgtgggcag ttatcgcact tggctttaat acaagttacc ttcgtttata cagtgccttg
    10441 attttagcag tctgcctcat gattccaaca tttaagcaaa caatcttgaa aggagccaag
    10501 ttaagcaaat gacagcaatt gtagaattaa aaaatgcaac caaaatcgtt aaaaatggct
    10561 ttgatgaaga aaagattatt ttaaatgatg tttccttaga aatttttgaa cgggacttta
    10621 tcacgatttt gggcggaaat ggtgctggaa aatcaaccct ctttaacact atagcaggga
    10681 ccttatcact aactagtgga actatccgta ttttaggtga agaactcact aagttttcac
    10741 ccgagaagcg tgccaagtac ctgtctcgtg tcttccaaga tccaaagatg gggacagctc
    10801 cccgtatgac ggtcgctgaa aatcttttaa tcgccaagtt tcgtggtgaa aagcgtggat
    10861 tgttaccacg acgcttgact agctataagg atgaatttca ggcaaccatt gaaaaagtag
    10921 gaaatggtct tgagaaacac ttgaatacac cgattgagtt cttatcaggt ggacaaagac
    10981 aggctttgag tctcttgatg gcaaccttga agcgacctga attactcctg ttagatgagc
    11041 atactgctgc cctggatcca aagactagtg ttgctttgat ggaattgaca gatgaatttg
    11101 ttaagaaaga tcagctaaca gcccttatga ttactcatca tatggaagat gctctcaaat
    11161 acggcaatcg cttgattgtc atgaaagaag gacggattat ccaagattta aaccaagaag
    11221 aaaaagcaaa aatgaaaatc tctgattatt atcaactctt tgaataaagt agggaaaatg
    11281 agtgaaatgg tttacttttt ttctgaaata aagtatacta tataaagtaa actatgataa
    11341 catggaggta ttgtgtatgg ttgacaaaca agtcattgaa gaaatcaaaa acaatgccaa
    11401 cattgtggaa gtcataggag atgtgatttc tttacaaaag gcaggacgga actatctagg
    11461 gctctgtcct tttcatggtg aaaaaacacc ttctttcaac gttgtagagg ataagcagtt
    11521 ttatcactgt ttcggttgtg gtcgctcagg tgatgtcttt aagttcatcg aggagtacca
    11581 aggggttccc tttatagagg cagtccaaat cttaggtcag cgtgttggaa ttgaggttga
    11641 aaaaccgctt tatagtgagc agaagccagc ctcacctcac caagctcttt atgatatgca
    11701 cgaagatgca gccaaatttt accatgcgat tctcatgaca acgactatgg gcgaagaggc
    11761 cagaaattac ctttatcagc ggggtttgac agatgaagtg cttaaacatt tttggattgg
    11821 tttagcacct ccagaacgaa actatctcta tcaacgtttg tctgatcagt atcgtgaaga
    11881 ggatttactg gattcaggcc tgttttatct ctcggatgcc aatcaatttg tagacacctt
    11941 tcacaatcgc attatgtttc ccctgacaaa tgaccaagga aaggtcattg ccttctcagg
    12001 tcgtatctgg caaaaaacgg attcacaaac ttctaagtat aaaaacagcc gatcgactgc
    12061 aatttttaac aaaagttacg aattatatca tatggatagg gcaaaaaaat cttctggaaa
    12121 agctagtgag atttacttga tggaaggatt catggatgtt attgcagcct atcgggctgg
    12181 aatcgaaagt gctgtggcgt cgatgggaac ggccttgagt cgagagcatg ttgagcatct
    12241 gaaaaggtta accaagaaat tggttcttgt ttacgatgga gataaggctg ggcaagccgc
    12301 gacattgaaa gcattggatg aaattggtga tatgcctgtg caaatcgtca gcatgcctga
    12361 taacttggat cctgatgagt atctacaaaa aaatggtcca gaagacttgg cctatctatt
    12421 aacgaaaact cgtattagtc cgattgagtt ctacattcat cagtacaaac ctgaaaacag
    12481 tgaaaatctg caggctcaga ttgagtttct tgaaaaaata gctcccttga ttgttcaaga
    12541 aaagtccatc gctgctcaaa acagctatat tcatatttta gctgacagtc tggcgtcctt
    12601 tgattatacc cagattgagc agattgttaa tgagagtcgt caggtgcaaa ggcagaatcg
    12661 catggaagga atttccagac cgacgccaat caccatgcca atcaccaagc agttatcggc
    12721 tattatgagg gcagaagccc atctactcta tcggatgatg gaatcccctc ttgttttgaa
    12781 cgattaccgt ttgcgagaag actttgcatt tgctacacct gaatttcagg tcttatatga
    12841 cttgcttggc cagtatggaa atcttcctcc agaagtttta gcagagcaga cagaggaagt
    12901 tgaaagagct tggtaccaag ttttagctca ggatttgcct gctgaaatat cgccgcagga
    12961 acttagtgaa gtagagatga ctcgaaacaa ggctctcttg aatcaggaca atatgagaat
    13021 caaaaagaag gtgcaggaag ctagccatgt aggagataca gatacagccc tagaagaatt
    13081 ggaacgttta atttcccaaa agagaagaat ggagtaataa tggcaacaaa acaaaaagaa
    13141 gtaacaacat ttgacgtaca ggtagcagaa tttatccgta atcataagca aaaagggaca
    13201 gcaacagatg atgaaatcaa tgcaagtctg gttattcctt ttaccttgga cgctgatggg
    13261 attgaagatc tcttgcaacg gattcaggat gcaggaattt ctatcacaga taacgaagga
    13321 aatccaagtg cgcgtgttct tagcaatgaa gaagaaccag aactcagcga tgaggacttg
    13381 attgggtcaa cttctgctaa ggtcaatgac cctgtccgta tgtacttgaa agaaataggg
    13441 gtcgttcctc tcttgaccaa tgaagaggag aaagagttgg cactggctgt tgaagctggt
    13501 gatatcgaag ccaaacaacg tcttgcggaa gccaatcttc gtttggttgt ttccattgcc
    13561 aaacgctatg tcggtcgtgg catgcagttc cttgacttga ttcaagaagg aaatatgggc
    13621 ttgatgaagg cggttgacaa gtttgactat tctaaagggt tcaagttttc aacttatgca
    13681 acttggtgga ttcgtcaggc tatcactcgt gctattgcgg accaagctcg taccatccgt
    13741 atcccagttc acatggttga aactatcaat aaattggttc gtgaacagcg gaatctcctt
    13801 caagaattgg ggcaagatcc gacaccagaa cagattgctg aacgaatgga tatgacacct
    13861 gataaggttc gtgaaatctt gaagattgcc caagaaccag tatctcttga aactcctatc
    13921 ggtgaagagg acgatagcca ccttggagac tttatcgaag atgaagtgat tgaaaatcca
    13981 gtggattata cgactcgtat cgtcttgcgt gagcaattgg atgaaatctt agatactctt
    14041 acagaccgtg aagaaaatgt tctgcgtcta cgttttggac tagatgatgg aaaaatgcgc
    14101 acacttgaag atgtggggaa agtctttaac gtaactcgtg agcgtatccg tcagattgaa
    14161 gcaaaggctt tgagaaaact acgccaacca agtcgtagca aaccgcttcg tgattttatt
    14221 gaagactaag agtgaggaaa atatggctta tacagaagag caaattgaaa acatcaaaac
    14281 acggatttta acagccttgg aagaagtcat cgaccctgag ttgggaatcg atattgtcaa
    14341 tcttggtttg atctatgaga ttcgttttga cggtgacaca gggcaaacag agattgacat
    14401 gactttgaca actatgggtt gtcccttagc agaccttttg acagaccaga tttatgatgc
    14461 tatgatagag gttccagaag taacggatac tgaggttaaa ttagtctggt atccagcctg
    14521 gacagttgaa aaaatgagtc gctatgcccg cattgcccta ggcattaagt aaacatataa
    14581 aagcatgtga gagactgttg gaaaagcgag gaaatttccc ctcttttcct ctagtctctc
    14641 ctttcttttg ctgattttat tcaaagaaaa tgatataata gtagttatgg agaaaaagaa
    14701 attacgcatc aatatgttga gttcaagtga gaaagtagca ggacagggag tttcaggtgc
    14761 ttaccgtgaa ttagttcgtc ttcttcaccg tgctgccaag gaccaattga ttgttacaga
    14821 aaatcttcca atcgaggcag atgtgactca ctttcatacg attgattttc cctattattt
    14881 atcaaccttc caaaagaaac gctcagggag aaagattggc tatgtgcatt tcttgccagc
    14941 tacacttgag ggaagtttga aaattccatt tttcttaaag ggaattgtga aacgctatgt
    15001 attttctttt tacaaccgga tggagcactt ggttgtggtc aatcctatgt ttattgagga
    15061 tttggtagca gctggtattc cacgtgaaaa agtgacctat attcctaact ttgtcaacaa
    15121 ggaaaaatgg catcctctac cacaagaaga ggtagtcaga ctgcgcacag atcttggtct
    15181 tagtgacaat cagtttatcg tagtaggtgc tgggcaagtt cagaaacgta aagggattga
    15241 tgactttatc cgtctggctg aggaattgcc tcagattacc tttatctggg ctggtggctt
    15301 ctcttttggt ggtatgacag atggttatga acactataag aaaattatgg aaaatccccc
    15361 taaaaatttg atttttccag gcattgtatc gccagagcgg atgcgcgaat tgtatgctct
    15421 agcggatctt ttcttgttgc ctagttacaa tgagctcttt cctatgacta ttttagaagc
    15481 tgcgagttgt gaggctccta ttatgttgcg tgatttagat ctctataagg taattttgga
    15541 gggaaattat cgggcgacag cgggtagaga agagatgaaa gaggctattt tggaatatca
    15601 agcaaatcct gctgccttaa aagatctcaa agaaaaggct aagaatattt ccagagagta
    15661 ttctgaagag catctgttac aaatctggtt ggacttttat gagaaacaag ccgctttagg
    15721 gagaaagtaa aaagtgaggt aatctatgcg aattggttta tttacagata cctattttcc
    15781 tcaggtttct ggtgttgcga ccagtattcg aaccttgaaa acagaacttg aaaagcaggg
    15841 acatgctgtt tttatcttta cgacgacaga taaggatgtc aatcgctacg aagattggca
    15901 aattatccgc attccaagtg ttcctttctt tgcttttaag gatcgtcgct ttgcctaccg
    15961 aggttttagc aaggcacttg aaattgctaa acagtatcag ctagatatta tccatactca
    16021 gacagaattt tctcttggcc tgttggggat ttggattgcg cgtgaattga aaattccagt
    16081 catccatacc tatcacaccc agtatgaaga ctatgtccat tatattgcta aggggatgtt
    16141 gatccggccg agtatggtca agtatctggt tagaggtttc ctgcatgatg tggatggggt
    16201 tatttgtcct agtgagattg tccgtgactt gctatctgat tataaggtca aggttgaaaa
    16261 acgggtcatt cctactggga ttgaattagc caagtttgag cgtccggaaa tcaagcagga
    16321 aaatttgaaa gaactgcgta gtaaactagg gattcaagat ggtgaaaaga cgttgcttag
    16381 tctttcgaga atctcctatg aaaaaaatat tcaagcagtt ttagcagcct ttgctgatgt
    16441 tctgaaagag gaagacaagg ttaaactggt agtagctggg gatggccctt atctgaatga
    16501 cctcaaagag caagctcaga acctagagat tcaagactca gtcatcttta cagggatgat
    16561 tgctcctagt gagacggctc tttactataa agcggcggat ttcttcattt cggcatcgac
    16621 aagcgaaacg caaggtttga cctacttgga aagcttagcc agtggaacac ctgtcattgc
    16681 tcacggaaat ccttatttga acaacctcat cagtgataaa atgtttggaa ccttgtacta
    16741 tggagaacat gatttggctg gtgctatttt ggaagccctg attgcaacac cagacatgaa
    16801 cgagcatacc ttatcagaga aattgtatga gatttcagct gagaactttg ggaaacgagt
    16861 gcatgagttt tatctggatg ccattatttc aaataacttc cagaaagatt tggctaaaga
    16921 tgatacggtc agtcagcgta tctttaagac agttttgtat cttcagcaac aggtggttgc
    16981 tgtacctgta aaaggatcta gacgcatgtt gaaggcttca aaaacacagt tgatcagtat
    17041 gagagactat tggaaagacc atgaagaata gaaagaggaa cagctatgaa aaaaacaatt
    17101 aatgagaagc ggtcgtgata aaaagattgc gggtgtttgt gctggggtgg cccattatct
    17161 ggatatggat ccgactatcg ttcaagtcat ttggggtgtt cttacttgct gttacggagc
    17221 tggaattgta gcttacatta ttttatggat tatcgcacca gtagcaactg actattgaaa
    17281 actagctcaa ttcatgctaa gataatagaa aatagaatgt aacgaaggag agaaaaatgg
    17341 catttggaga taatggaaat cgtaaaaaaa ctatgtttga gaaaataacc ttgtttatcg
    17401 tgattatcat gctagtagca agtttattgg gaatttttgc aactgcaatt ggtgccctca
    17461 gtaatctata aaatagattc aagaaaattt agtgactggg atttcccagc ccttttttaa
    17521 agtgagaaga aataatgagt atgtttttag atacagctaa gattaaggtc aaggctggta
    17581 atggtggcga tggtatggtt gcctttcgtc gtgaaaaata tgtccctaat ggaggccctt
    17641 ggggtggtga tggtggtcgt ggaggcaatg tggtcttcgt tgtagacgaa ggactacgta
    17701 ccttgatgga tttccgctac aatcgtcatt tcaaggctga ttctggtgaa aaagggatga
    17761 ccaaagggat gcatggtcgt ggtgctgagg accttagagt tcgagtacca caaggtacga
    17821 ctgttcgtga tgcggagact ggcaaggttt taacagattt gattgaacat gggcaagaat
    17881 ttatcgttgc ccacggtggt cgtggtggac gtggaaatat tcgtttcgcg acaccaaaaa
    17941 atcctgcacc ggaaatctct gaaaatggag aaccaggtca ggaacgtgag ttacaattgg
    18001 aactaaaaat cttggcagat gtcggtttag taggattccc atctgtaggg aagtcaacac
    18061 ttttaagtgt tattacctca gctaagccta aaattggtgc ctaccacttt accactattg
    18121 taccaaattt aggtatggtt cgcacccaat caggtgaatc ctttgcagta gccgacttgc
    18181 caggtttgat tgaaggggct agtcaaggtg ttggtttggg aactcagttc ctccgtcaca
    18241 tcgagcgtac acgtgttatc cttcacatca ttgatatgtc agctagcgaa ggccgtgatc
    18301 catatgagga ttacctagct atcaataaag agctggagtc ttacaatctt cgcctcatgg
    18361 agcgtccaca gattattgta gctaataaga tggacatgcc tgagagtcag gaaaatcttg
    18421 aagaatttaa gaaaaaattg tctgaaaatt atgatgaatt tgaagagtta ccagctatct
    18481 tcccaatttc tggattgacc aagcaaggtc tggcaacact tttagatgct acagctgaat
    18541 tgttagacaa gacaccagaa tttttgctct acgacgagtc cgatatggaa gaagaagctt
    18601 actatggatt tgacgaagaa gaaaaagcct ttgaaattag tcgtgatgac gatgcgacat
    18661 gggtactttc tggtgaaaaa ctcatgaaac tctttaatat gaccaacttt gatcgtgatg
    18721 aatctgtcat gaaatttgcc cgtcagcttc gtggtatggg ggttgatgaa gcccttcgtg
    18781 cgcgtggagc taaagatggg gatttggtcc gcattggtaa atttgagttt gaatttgtag
    18841 actaggagac tggtatggga gataaaccga tatctttccg agatgcggat ggtaattttg
    18901 tttccgccgc agacgtttgg aatgaaaaga aattggaaga actatttaat cgtctcaatc
    18961 caaatcgtgc cttgagattg gcacgaacta aaaaggaaaa tccatctcag taaagaagct
    19021 aaaaaatccc gtgcctcatc agacacggga ttttgtggta cgacaggcat gtatagcaaa
    19081 ctgaatctgg aatagcacag catatcttct aaaatattgc tataaattga tttgaatttc
    19141 aaaattaaat tgttttattc ttatttcaat ttgttatagt atatctgatg tcaaagttct
    19201 cggcgagtca aatagtgatt cccaagcctg actatcgtga ggtagcggat taaaatggtc
    19261 tggggataga ccgttttaag tctgatgctg gaaataagaa ttgtcagaag aagggatagc
    19321 gaaatcgtgg ctctacgaac aggaacgtga taataaggcg tatatagcga ataagagggc
    19381 ctcaaactct aaagtccaaa aaggtagtcg taacctatat gcgtaaatca tgagagtaat
    19441 tgaattcgta ctaagatttt ctatttttac tgtaaccttt taacgtcctc atatcttgta
    19501 tacacgagga aagatgtacg acttatcccg tgaggtctat cactataaag agaaaacgac
    19561 agatagaagt gatcctgagt cacggttatc tttaaaatag attgtctgat aggatgctag
    19621 cctgaaaacg tcttgttcat gaaatatagg acggtatgta taaaacgctt ctgtgaactg
    19681 agagaagggg gagaagttct tgctaaaatt tagttgaaca gccgtattcc gatacttaga
    19741 taagagatct agtcttagct cctactcagt ttcaggggat aaaaaagggg caatagcgat
    19801 tcgagaaaga ttatactctt cgaaaatctc ttcaaatcac gtcaatatcg ccttgccgta
    19861 tgtgtaggat actaactacg tcagttccat ctacaatctc aaaacagtgt tttgagcaac
    19921 ctgcggctag tttcctagtt tgatctttga tttttattga gtattagtaa ttcagttact
    19981 aactcgtcaa ctctgattta tccaataaaa ttgaaaagga tggaaaaaag gataaattta
    20041 tgatatactt tattttgaag accttattag aaatcttgaa agagtattga aaacttagaa
    20101 tgagaaaaat tgttatcaat ggtggattac cactgcaagg tgaaattact attagtggtg
    20161 ctaaaaatag tgttgtggcc ttaattccag ctattatatt ggctgatgat gtggtgactt
    20221 tggattgtgt tccagatatt tcggatgtag ccagtcttgt cgaaatcatg gaattaatgg
    20281 gagctactgt taagcgttat gacgatgtct tggagattga tccaagaggt gttcaaaata
    20341 ttccaatgcc ttatggtaaa attaacagtc ttcgtgcatc ttactatttt tatgggagcc
    20401 tcttaggccg ttttggtgaa gcgacagttg gtctaccggg aggatgtgat cttggtcctc
    20461 gtccgattga cttacacctt aaggcgtttg aagctatggg tgccactgct agctacgagg
    20521 gagataacat gaagttatct gctaaagata caggacttca tggtgcaagt atttacatgg
    20581 atacggttag tgtgggagca acgattaata cgatgattgc tgcggttaaa gcaaatggtc
    20641 gtactattat tgaaaatgca gcccgtgaac ctgagattat tgatgtagct actctcttga
    20701 ataatatggg tgcccatatc cgtggggcag gaactaatat catcattatt gatggtgttg
    20761 aaagattaca tgggacacgt catcaggtga ttccagaccg cattgaagct ggaacatata
    20821 tatctttagc tgctgcagtt ggtaaaggaa ttcgtataaa taatgttctt tacgaacacc
    20881 tggaagggtt tattgctaag ttggaagaaa tgggagtgag aatgactgta tctgaagaca
    20941 gcatttttgt cgaggaacag tctaatttga aagcaatcaa tattaagaca gctccttacc
    21001 caggctttgc aactgatttg caacaaccgc ttacccctct tttactaaga gcgaatggtc
    21061 gtggtacaat tgtcgatacg atttacgaaa aacgtgtaaa tcatgttttt gaactagcaa
    21121 agatggatgc ggatatttcg acaacaaatg gtcatatttt gtacacgggt ggacgtgatt
    21181 tacgtggggc cagtgttaaa gcgaccgact taagagctgg ggctgcacta gtcattgctg
    21241 ggcttatggc tgaaggtaaa actgaaatta ccaatatcga gtttatctta cgtggttatt
    21301 ctgatattat cgaaaaatta cgtaatttag gagcggatat tagacttgtt gaggattaaa
    21361 ccgtagaggt gtttatgaat atttggacca aattagcaat gttttctttt tttgaaacgg
    21421 atcgcttgta tttgcgtcct ttctttttta gtgatagtca ggacttccgc gagatagctt
    21481 caaatccaga aaatcttcaa tttattttcc caacgcaggc aagtctggaa gaaagtcaat
    21541 atgcactggc caattacttt atgaagtccc ctttgggagt gtgggcaatt tgtgaccaga
    21601 aaaatcaaca aatgattggt tctattaaat ttgagaagtt agatgaaatc aaaaaagaag
    21661 ctgagcttgg ctattttttg agaaaagatg cttggtcgca aggatttatg acagaggttg
    21721 ttagaaaaat ttgtcagctt tcttttgagg aatttggctt aaaacaatta tttatcatta
    21781 cccaccttga aaatgaagct agccaaagag ttgctcttaa gtctggattt agtttgttcc
    21841 gtcagtttaa gggaagtgat cgttacacaa gaaaaatgcg ggattatctt gaatttcggt
    21901 atgtaaaagg agagttcaat gagtaagcat caggaaattc taagctattt ggaggaatta
    21961 ccagtaggta aaagggtcag tgttcgtagc atttcgaatc atctaggagt tagtgatgga
    22021 acagcctatc gagctattaa agaagctgaa aaccgtggaa ttgtggagac ccgtcctaga
    22081 agtggaacaa ttcgtgttaa atcccagaaa gttgctatag agagattaac gtttgctgaa
    22141 attgcagaag tgacttcttc tgaggttctg gctgggcaag aaggtttaga gagagagttt
    22201 agtaagtttt caattggtgc catgactgaa caaaatatct tgtcttacct tcatgatggg
    22261 gggctcttga ttgtcggaga ccgaacccgt attcagttgc tagccttgga aaatgaaaat
    22321 gcagttctgg ttacaggggg atttcaggtt catgatgatg tgcttaaact ggccaatcaa
    22381 aaagggattc ctgttctaag aagtaagcat gataccttta ccgtcgcgac catgatcaat
    22441 aaagccttgt caaatgtcca aatcaagact gatattctga cagttgagaa actttatcgc
    22501 cctagtcatg agtatggttt tctgagagag acagatacag ttaaagatta tttggacttg
    22561 gttcgtaaga atcgtagcag ccgtttccct gttatcaatc aacatcaggt cgttgttggt
    22621 gttgtaacca tgagagacgc tggtgataaa tcaccaagca cgacaattga taaggttatg
    22681 tctcgtagtc tattttgggt tggattatcg acaaatattg ccaatgtgag tcaacggatg
    22741 atcgcagaag actttgaaat ggtaccagtt gttcgaagca atcaaacttt gcttggcgtt
    22801 gtgacgcgac gagatgtcat ggagaagatg agccgttccc aagtttcggc tctaccaact
    22861 ttttctgagc agattggaca aaagctctct tatcaccatg atgaagtagt cattacagtg
    22921 gaacccttta tgctagaaaa aaatggagtt ttggctaatg gtgtattggc agaaattctg
    22981 acccacatga cccaagattt agttgttaat agtggtcgca atctcattat cgagcagatg
    23041 ctgatctact ttttgcaggc tgttcagata gatgatatat tgcgcattca ggcacggatt
    23101 attcatcata cgagacggtc agctataatt gattacgata tttatcatgg tcaccagatt
    23161 gtttcaaaag caaatgtgac tgttaaaatt aattagaaac taggagaaaa gatgataaca
    23221 ttaaaatcag ctcgtgaaat cgaagctatg gacaaggctg gtgattttct agcaagtatt
    23281 catataggct tacgtgattt gattaagcca ggcgtagata tgtgggaagt tgaagaatat
    23341 gtccgccgtc gttgtaaaga agaaaatttc cttccacttc agattggggt tgacggtgcc
    23401 atgatggact atccttatgc tacctgttgc tctcttaacg atgaagtggc tcacgctttc
    23461 cctcgtcatt atatcttgaa agatggtgat ttgctcaaag ttgatatggt tttgggaggt
    23521 cccattgcta aatccgacct gaatgtctca aaattaaact tcaacaatgt tgaacaaatg
    23581 aaaaaataca ctcagagcta ttctggtggt ttagcagact catgttgggc ttatgctgtt
    23641 ggtacaccgt ccgaagaagt caaaaacttg atggatgtaa ccaaagaagc tatgtacaag
    23701 ggtattgagc aagctgttgt tggaaatcgt atcggtgata tcggtgcggc tattcaagaa
    23761 tacgctgaaa gtcgtggtta cggtgtagtg cgtgatttgg ttggtcatgg tgttggccca
    23821 actatgcacg aagaaccaat ggttcctaac tatggtattg caggtcgtgg actccgtctt
    23881 cgtgaaggaa tggtcttaac cattgaacca atgatcaata caggcgattg ggaaattgat
    23941 acagatatga aaactggttg ggcgcataag accattgacg gtggattgtc atgtcagtat
    24001 gaacaccaat ttgtcattac gaaagatgga cctgttatct tgactagcca aggtgaagaa
    24061 ggaacttatt aataaaaagt gaaaagacta ctggaagttt attttgataa aaaatccagt
    24121 agatcttttc ataataaaac gcattgtatc aagtgttagg agctgatatc atgcgttttt
    24181 ctgcttttaa gattttttcc aactctgttt gtaagcgcat cataacaaag ggtctaggat
    24241 tcagggctct cctcctatat actattagta aagtaaaact aagagaggat attttagtgt
    24301 cgcagtctat tgttcctgta gagattccac aatattgtcg ttttgattct aaaaagagaa
    24361 atggaattct gtttaacgtt cgtattgcca atcttaaatt tacctttttt agattagact
    24421 tcctgcgaaa
//
LOCUS       DBERCW010000031        23594 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.031, whole genome shotgun sequence.
ACCESSION   DBERCW010000031 DBERCW010000000
VERSION     DBERCW010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23594
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.031"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            149..871
                     /locus_tag="ACL72M_001532"
     CDS             149..871
                     /locus_tag="ACL72M_001532"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS0716641.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1088..2422
                     /gene="pepC"
                     /locus_tag="ACL72M_001533"
     CDS             1088..2422
                     /gene="pepC"
                     /locus_tag="ACL72M_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGS0716642.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(2478..3389)
                     /locus_tag="ACL72M_001534"
     CDS             complement(2478..3389)
                     /locus_tag="ACL72M_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0716643.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3413..4216)
                     /locus_tag="ACL72M_001535"
     CDS             complement(3413..4216)
                     /locus_tag="ACL72M_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGS0716644.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4244..5233)
                     /locus_tag="ACL72M_001536"
     CDS             complement(4244..5233)
                     /locus_tag="ACL72M_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0716645.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5466..6485)
                     /gene="adhP"
                     /locus_tag="ACL72M_001537"
     CDS             complement(5466..6485)
                     /gene="adhP"
                     /locus_tag="ACL72M_001537"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGS0716646.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWAVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(6837..7649)
                     /locus_tag="ACL72M_001538"
     CDS             complement(6837..7649)
                     /locus_tag="ACL72M_001538"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0716647.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7839..9257
                     /locus_tag="ACL72M_001539"
     CDS             7839..9257
                     /locus_tag="ACL72M_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGS0716648.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            9310..10017
                     /locus_tag="ACL72M_001540"
     CDS             9310..10017
                     /locus_tag="ACL72M_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0716649.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            10112..11086
                     /gene="folP"
                     /locus_tag="ACL72M_001541"
     CDS             10112..11086
                     /gene="folP"
                     /locus_tag="ACL72M_001541"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGS0716650.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALATGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            11088..12410
                     /locus_tag="ACL72M_001542"
     CDS             11088..12410
                     /locus_tag="ACL72M_001542"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS0716651.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            12391..12945
                     /gene="folE"
                     /locus_tag="ACL72M_001543"
     CDS             12391..12945
                     /gene="folE"
                     /locus_tag="ACL72M_001543"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGS0716652.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            12988..13800
                     /gene="folK"
                     /locus_tag="ACL72M_001544"
     CDS             12988..13800
                     /gene="folK"
                     /locus_tag="ACL72M_001544"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGS0716653.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(13845..14162)
                     /locus_tag="ACL72M_001545"
     CDS             complement(13845..14162)
                     /locus_tag="ACL72M_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGS0716654.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            14519..14965
                     /gene="rplM"
                     /locus_tag="ACL72M_001546"
     CDS             14519..14965
                     /gene="rplM"
                     /locus_tag="ACL72M_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGS0716655.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            14984..15376
                     /gene="rpsI"
                     /locus_tag="ACL72M_001547"
     CDS             14984..15376
                     /gene="rpsI"
                     /locus_tag="ACL72M_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGS0716656.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(15638..16060)
                     /locus_tag="ACL72M_001548"
     CDS             complement(15638..16060)
                     /locus_tag="ACL72M_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0716657.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            16207..16383
                     /locus_tag="ACL72M_001549"
     CDS             16207..16383
                     /locus_tag="ACL72M_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716658.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            16785..18998
                     /locus_tag="ACL72M_001550"
     CDS             16785..18998
                     /locus_tag="ACL72M_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGS0716659.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(19220..19696)
                     /locus_tag="ACL72M_001551"
     CDS             complement(19220..19696)
                     /locus_tag="ACL72M_001551"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGS0716660.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQAQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFSKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            19919..23122
                     /locus_tag="ACL72M_001552"
     CDS             19919..23122
                     /locus_tag="ACL72M_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGS0716661.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKGG
                     AITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYYWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            23502..23594
                     /locus_tag="ACL72M_001553"
                     /pseudo
     CDS             23502..23594
                     /locus_tag="ACL72M_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005576373.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         7165 a         4338 c         5213 g         6878 t
ORIGIN      
        1 tttgaggttg cagatagaac tgacgaagtc agtaacatat atacggcaag gcgacgttga
       61 cgcggtttga agagattttt gaagagtatg aaacgaaaag gaggttggtc attgtactag
      121 cctccttttg atatgatata atagttctat gagattagat aaatttttag ttgcctgtgc
      181 ggtgggaagt cggactgagg tcaaaaactt gctcaaggct gggcgcgtga ctgtaaatgg
      241 taaaaaagaa aaatcagcta aattgcagat tgatgaaaaa atagatgaga ttcgctttga
      301 tgggcaagtg ttggagtatg aagagtttgt ctactacatg atgaacaagc ccaaaggagt
      361 tatctcagcg actgaggatc ccaagcacag aaccgttctg gacttgttgg atgacttggc
      421 gcggagtaag gaagtttttc cagtaggacg cttggatatt gacacgcatg gtcttttgct
      481 cttgaccaat aatggtcagc tggctcatgt tcttctttcg cccaagcgtc atgtggacaa
      541 gacttatcag gctcaggtca agggaattat gacccaagaa gatgtggaga catttatcaa
      601 gggcattccg ctcaaagact ttacctgtca gcccgctaga ctggagattc tttccacaga
      661 tgcagaaaag aatcagagcc aaatccgtgt gaccattgca gaagggaagt ttcatcagat
      721 caagcgtatg gtgggctact gtggcaagga agtggtggac ttgcaacgat tgactatggg
      781 aactttagta ttagatgaga acctggaacg aggggaatgg cgtcgcttga ccaaggaaga
      841 attagaaatt ctccgcgcta atattattta atttagttta atactcaatg aaaatcaaag
      901 agcaaactag gaaactagcc gcaggctgta cttgagtacg gcaaggcgac gttgacgtgg
      961 tttgaagaga ttttcgaaga gtataaattc gaaaaaggtg agggagaatg tccttacctt
     1021 ttatgttttt tagttgcttc ctttgtgaaa agagttataa tagactgtag aataaaagga
     1081 ggaatctatg aacgcgattc aagaatcatt tactgataaa ctatttgcca actatgaagc
     1141 aaatgtaaaa taccaagcga ttgaaaatgc tgccagccac aacggaattt ttgcagctct
     1201 ggaacgtcgc caaagccatg tagacaacac acctgttttc tcattggatt taaccaagga
     1261 caaggtcact aaccagaaag cgtctggtcg ttgctggatg tttgcggctc tcaacacctt
     1321 ccgccacaaa ctcatctcgc aatacaaatt ggagaacttt gagttgtcac aagcccacac
     1381 tttcttctgg gataagtatg agaaatcaaa ctggttcttg gagcaagtca ttgcgacttc
     1441 agaccaagaa ttgactagcc gcaaggttag cttcttactc caaacacctc aacaagatgg
     1501 tggtcaatgg gatatggtcg tttccctctt tgaaaaatac ggtgtcgtgc ctaagtcagt
     1561 ttatcctgag tctgtttcat ctagcagcag tcgtgagcta aatgcgatcc ttaataaatt
     1621 gcttcgtcaa gatgctcaaa tcttgcgtga tttgcttgtt tctggtgcag atcaagtgac
     1681 tgttcaagct aagaaagaag acctcttgca agaaatcttt aactttcttg ctatgtcatt
     1741 aggacttcca ccacgcaagt ttgactttgc ttatcgcgat aaagataaca actacaaaag
     1801 tgaaaaagga atcacaccac aagagttcta caagaaatat gtcaatcttc ctttagaaga
     1861 ctacgtttct gttatcaatg ctccaactgc tgataaacct tacggaaaat cttacacagt
     1921 tgagatgttg gggaatgtgg ttggtagccg tgcagttcgt tacatcaacg ttccaatgga
     1981 gcgcttgaaa gaattggcga ttgcccaaat gcaagcaggt gagactgttt ggtttggttc
     2041 tgatgtcggc cagctcagta accgtaaggc tggaatcctt gcgacagatg tttatgactt
     2101 tgaatcaagc atggacatta aacttactca agacaaggct ggacgtttgg actatagcga
     2161 aagcttgatg acccacgcca tggtcttgac aggtgttgac ttggacgaaa atggtaaatc
     2221 aaccaagtgg aaggttgaaa actcatgggg agacaaggtc ggtacagatg gttactttgt
     2281 tgcctcagac gcttggatgg acgaatacac ataccaaatc gttgttcgta aggaattgct
     2341 gacagcagaa gaacaagctg cctatggagc agaaccaatt gtacttgcac catgggatcc
     2401 aatgggagcc ttggctaaat aaaagcatag aaaaaaggaa tcagatttta gaacctggtt
     2461 cctttttagt tgcttgatta catgatgtga agaacatgtg ccacaatacc cactgcgaag
     2521 agggcaagga taatagtgat tggagatact tttttcttaa gtaagtacat gcaaagtaaa
     2581 gtaaggagta gtcctgataa tccaggaatc aacatatcca agttttgttg gaaagtagta
     2641 actttttcag gagtttgaga caatccttgt cctacttgtg cgaatgcttc ttggatacct
     2701 ttagaccctt ctggcaattt atcccaatgg atataagcct tttcatctag ttgaacttta
     2761 gaaacatcga aagcaaattt aatatttacc cagcgttgaa caaggacagc aagaatgaac
     2821 atcccaagga tagaagctcc tttagtgata tcttgaagga taccaccaga catatcttta
     2881 gtgatttctg atccagcctt gtatccaatc tcttgaacat accacaagaa tgacatacga
     2941 atcaagttcc atgcaacaaa gaagaggagt ggccccaaga tattgccagt aagggcaagt
     3001 gaagcaccga gagatccaag gattgggcgt actgtaaacc agaatactgg gtcaccgata
     3061 ccagcaagag gtcccatcat accgatttta accccttgga tagcagcgtc atcgatttcc
     3121 acaccgttag cacgttcttc ttcaagcgca agagtaaccc ccatgactgg agcagctacg
     3181 tatggatgag tgttgaagaa ctcaaggtga cgctcaagag cagcgatttg atcttctttt
     3241 ttagtataga gttttttgat agctggaatg agtgtataag cccagcccaa gttttgcatc
     3301 cgttcaaagt tccaagaccc ttgtaagaag gttgaacgcc accaaacttt tttacgatct
     3361 gatttagtta attgaagttt ttcagtcatg atgttttcag tcctttctta tcttagtagt
     3421 cttctaggat atcgccgatt gggtcgttag aagttgcggc tcctccgcca ccatttccac
     3481 cagttttaga aaggtgaagg tagataagag cgatagcaac accgatagca ccgaatccga
     3541 ttagagtaat atctgacaca gcagcgagaa cgaaaccaag agcgaagaat ggccatactt
     3601 cacgagttgc catcatgttg ataaccatgg cgtaaccaac ggcaacgacc ataccaccac
     3661 cgatagccat accatctttg agccagtctg gcatggcact aaggatactt tgtacagttt
     3721 cagttggtac cataaggaga agagctgcag gaagcgcgat acgaagtcct tggaagagta
     3781 gcgcaatgaa atgcgcacgc tccacagcgc cgaagtcacc ttttttagcg gcagcatctg
     3841 cagtatgaac caaaccaact gaaattgtac gaacaatcat tgtcaagaaa agtccagcta
     3901 cggcaagagg gatagcaacc gcttgggcaa caccgatacc agtcttggta aagtcaccac
     3961 caagaaccat gataatggca gcagcgacag aagcaagtgc agcatcagga gcgatagcag
     4021 caccgatatt tgaccaacca agggcaatca tttgaagcga tccaccgagg ataatccctg
     4081 cttccaagtg acctgttaca agcccaataa gggtacaggc tacaagtggt tggtgaaatt
     4141 ggaactggtc gaggatgcct tcaagacctg caaagaaggc tacaacgact actaaaacca
     4201 tagaaataat agacatgttt aaaatccttt cataaataat ggcttatttg acattggctt
     4261 tgttaatcaa gtcaaacaaa tcttttttag aatcatttgg tactttacgg acatcaaatt
     4321 caacacccaa gtcacgcatt ttttcaaatg tagcaacatc ttctttgtcc atagacaaaa
     4381 cggtattgac caatgtttta cctgttgagt gagccataga accaacgtta agagtcttga
     4441 ttggcacgcc gccttcgatg gcacgaaggg catcttgagg tgtttcaaac aagataaggg
     4501 catgtgtttc tccaaaacgt gggtcttttg aaatctcaat cagtttttga attggaacca
     4561 cgttagcctt gacattacct ggagctgctt gtttaatcaa ttctttacga aggtcgtctt
     4621 tagccacgtt atctgaagca acgatgatac gatttgcttt tgaatctgga gtccaagcag
     4681 ttgcaacctg accgtgaagt agacgtgtgt caagacgggc aagattgatt ttcaatttac
     4741 cgtctccgat aacagttcct tctgggatag cagtttgggc aactggagca gctgcagcgc
     4801 ttgcaacttc ttcaactgga tttagctctt ctggaagagc tttgatgcca tctttggctt
     4861 ctttaatgat attagcagcg actttttcta cacctgcagc agcgtccatg aggcgctctg
     4921 tgtaggcttg aatcaacatc ggtaagttaa gtcctgtgat gatggcaaac ttacgctcag
     4981 gattttctcc catcacgcga ctagcttggt taaatggaga accactccaa aggtcagcca
     5041 aaactagaac ctcatcttct gcgtcaaatg cagcaacagc gttattaaac ttagcgtata
     5101 gatcatcagg accttcattt ggcataaagg tcacaacttg aaccttttct tgttcaccaa
     5161 agatcataga tcctgactga tgaatacccg cagcaaattc gccgtggctc gcaataatga
     5221 ttccgatact cattattgtc attcctcctt ttttgtttta gttttcattt aagaaaactt
     5281 taagactgtt taagtataaa ccgttttcat aaaaaaagca actatttatc ataaaaaatt
     5341 aaaaaatttt tatttttgta tgttgatatg ttgagttttt gaggagtaat cttgaattct
     5401 tatttaaaat ttaatataaa aaagttggaa gaagcttcca acttttaaaa taggtttcta
     5461 ttagattagt gggtgaagtc gagtaccata cgtccttgga tttggccttt ttccatttcg
     5521 tcgaaaatgg caacagcatc ttctactgga cgtttttgaa caactgggac taccagacct
     5581 tctgcaccaa attggaaggc ttcttctaag tctttacgag ttccgacaag agaaccgatg
     5641 acttggattc catcgaggac tgttttaacg atgctgagtt ccatcatttc agaaggaaga
     5701 ccaacagcga cgacgcgacc accagcacga atggagtcaa cagcctggtt gaaggcaact
     5761 ttagacacag cagttacgac agctgaatga gctcctccat cagttttttc tttaatgagt
     5821 ccagctacat cttcaacttc gaggccgtta atcacaatgt cagcgcctac ttcttttgca
     5881 agggcaagtt tgtcattgtt gatatcgact gcgataacat gagcattgaa tactttttta
     5941 gcgtattgaa cagcgaggtt accaagtcca ccagcaccgt aaagaacagc ccattggcct
     6001 ggttcaactt ttgcttcttt gatagcttta taggttgtta ctccagcaca tgtgatagaa
     6061 gaagcttggg ctggatcaag tccgtcagga actttgacag catagtcagc agttacgata
     6121 cattgttcag ccataccacc gtctactgag tagccagcat ttttcactgt acggcaaagg
     6181 gtttcgcgac cagttgtaca gtattcgcaa gtgccacatc cttcaaagaa ccaagcaacg
     6241 ctgacgcggt caccgacttt aaggcttttc acatctggag caatctcttt aacgataccg
     6301 ataccttcgt gcccaagaac acgtcctggg acttgaccaa agtcaccatg agcaacgtgg
     6361 aggtcggtgt ggcaaacgcc acagtattca acttctacaa gtgcttcccc agtttcaagt
     6421 ggacggagta ctttttcttc aatagcaaca ccagtgcttt ctggatttac aacaacagct
     6481 ttcatagcta tcctccttga tattgaccga gaacagggac aacgggactg gattgatttt
     6541 ttgtcaacag agtcgagtgt gacgagctct cttgtattta tatgtgaagt atatcacaaa
     6601 agaaagcctt ttccaaggtt ttggagacaa aaagtagaac aatcgattaa ctggttgatg
     6661 agactgtgaa aagagcacaa agaccagctt gcaagctggt catactcttc gaaaatctct
     6721 tcaaaccacg tcagcttcat ctacaacctc aaagcagtgc tttgagcaac ctacggctag
     6781 cttcctagtt tgctctttga ttctcattga gtatcagtat aggttataag aataagttat
     6841 aagaataagt cttgtagggt tttggcaacc ccatcttggt cgttggtaag ggaaatttgc
     6901 tcatctgcat aagggagtag ctctggattg gcatttttca tggcataacc cttcccagca
     6961 aaagcgagca tttcggtatc attgtgttca tctccaaagg caatcaaatc ttttttgtca
     7021 cgattcatta tcttgagcaa gtagtccaaa gcaaaggcct tgttgacacc ttttggggta
     7081 cattcaagga tattgagcgg acctccccag gtattgatag aaagttgatg ctggtagaag
     7141 gcgttcattt cttttgccaa ggcatatttg tcactggctc tggtctgcaa gaggatacag
     7201 ttagggtcct tggtcaccaa ttcaggctgg aattgatctt caggctggaa agcttctaca
     7261 ccaaatagtt tgggattggc aatttcttca ttgggatttg taatgtagaa ttttttacga
     7321 tattctccag cgataaaatc ggcttgaatg tcctctgaac gttgaaccat atctagcaga
     7381 tattttttgt ctacagtcaa acacttttca aaatcccaaa cttggtctgg taaatgagta
     7441 agggatccgt tgaagttaat cataggagtg tctaagccca gttcacggta aaaatctttt
     7501 gacatacggt aagggcgacc tgtcgtaata ataacctgat ggcctttttc agcaactttt
     7561 ttgatggttt ttttggtaaa gtcagaaatt tgactgtctg agttgagcag ggttccatct
     7621 aggtcaactg caataatttt tttcgtcata tggacctttc tagtgtgttt tcagataaga
     7681 tgtcttctat tataacagaa agcaggcaga aaagcagatt ccaaacaaaa aatgaaattg
     7741 gattaatttc ttaaacaaat caaacaaaga cattgaaaaa gtgaatgata aatgatataa
     7801 ttctattatt gttcgtaaaa attaaaagga gattgatgat ggacaaatta tttaaactaa
     7861 aagagaacgg tacagacgtt cgtacagagg ttctcgctgg tttaacaact ttctttgcaa
     7921 tgagctatat tctctttgta aacccacaaa ttctttcgca aacaggaatg cctgctcagg
     7981 gtgtgtttct tgcaacgatt atcggtgcag ttgctggtac cttgatgatg gccttctatg
     8041 ctaacttgcc atacgctcaa gcaccaggta tgggactcaa tgccttcttt acctttacag
     8101 tcgtatttgg acttggttat tcatggcaag aagccctagc tatggtcttc atctgtggga
     8161 ttatttcatt ggttattacc ttgacaaatg ttcgtaaaat gatcattgaa tcgattccaa
     8221 atgcccttcg ctcggctatt tcagctggta tcggtgtctt ccttgcctat gtagggatta
     8281 agaatgctgg acttttgaaa tttacgattg atccaggcaa ctatactgtt gtaggagaag
     8341 gggctgacaa agctcaagca acgattgcag caaactcttc agcagttcca ggcttggtca
     8401 gctttaataa tccagctgtt ttagtggctc ttgcaggact tgccattact atcttctttg
     8461 tcatcaaagg gattaaaggg ggaattattc tctctatctt gacaacaact gttcttgcta
     8521 ttgcagttgg tttggttgat ttgtctagta tcgattttgc taataaccat gttggtgcag
     8581 cttttgaaga tttgaagaca atctttggtg cagctcttgg ttcagaaggt ttgggagctt
     8641 tggtttcaga tacagctcgc ttgcctgaaa ctctgatggc cattcttgcc ttctcattga
     8701 cagatatttt tgacacaatt ggtaccttga tcggtacagg tgaaaaagtt ggtattgtag
     8761 cgacaaatgg tgaaaatcac caatcagcca aattggataa ggctctttac tctgatttga
     8821 ttggaacgac agtcggtgcc attgcaggta cttcaaacgt aacgacttat gttgagtctg
     8881 ctgctggtat cggtgcaggt ggacgtactg gtttgacagc cttggttgta gctatctgtt
     8941 ttgcgatttc aagcttcttt agcccacttc tagcgatcgt accaacagcg gctacagctc
     9001 caatcttgat tatcgttggg attatgatgc ttggtagctt gaaaaatatc cattgggatg
     9061 atatgtctga agcagttcct gccttcttca catctatctt tatgggattc agctactcta
     9121 tcactcaagg gattgcagtt ggtttcttga cttacacttt gactaagctt gtcaaaggtc
     9181 aagttaaaga tgttcatgcc atgatttgga ttttggatgc cttgtttatc cttaactaca
     9241 tcagcatggc cttataatag aatgacccag ggggatttcc cccctttttt aatacaaagg
     9301 agataggtga tgaaagagaa aaatatgtgg aaagaattgt tgaatcgtgc aggctggatt
     9361 ttggtctttt tacttgccgt ccttttatat caggttcccc tagtggttac ctctattttg
     9421 actttaaaag aagtagccct gctacagtca gggctgatag ttactggcct ttcaattgtg
     9481 gttctggctc tatttattat gggagctcgt aaaaccaagt tagctagttt taatttttct
     9541 ttttttagag ctaaagattt ggcacgtttg ggcttgagtt atttagttat tgtcgggtca
     9601 aatatacttg gttctatctt gttgcaactg tcaaatgaga cgacaacagc taaccagtct
     9661 cagattaacg atatggttca gaatagttct ctgatttcta gcttcttctt gctagccttg
     9721 cttgctccaa tttgtgagga aatcttgtgc cgtgggattg ttcctaaaaa gattttccga
     9781 ggcaaggaga acttgggatt tgtagtcggt acgattgtgt ttgctttatt gcatcaacca
     9841 agtaatttac cttctttatt gatttatgga ggtatgtcga cagttctatc ttggacggcc
     9901 tacaagaccc aacgtttgga aatgtcgatc ttgcttcaca tgattgttaa tgggattgct
     9961 ttctgtttgt tggctcttgt ggtgattatg agtcggacat taggaatttc tgtttaaaag
    10021 tttttatgta ggaaccgacc tctttctact agggaaagat gaatgcaatc gtgtccatct
    10081 ttttcttttt atggtaaaat agaaaaataa tatgatgaaa atccttgagg gagtgaccga
    10141 tatgtcaagt aaagctaatc atgcaaagac agttatttgc ggaattatca atgtaacccc
    10201 agactccttt tcggacggtg gtcaattttt tgctcttgag caggcactcc agcaggctcg
    10261 taaattgata gcagaaggag ccagtatgct cgatatcggc ggagaatcga ctcggccggg
    10321 aagtagctat gttgagatag aagaggaaat ccagcgtgtt gttccagtga tcaaagcgat
    10381 tcgcaaggaa agtgatgtcc tcatctctat tgatacttgg aagagtcaag tagcagaggc
    10441 tgctttggct actggtgccg atctagtcaa tgatatcact ggtctcatgg gtgatgaaaa
    10501 aatggcccat gtggttgcta aagctggagc gaaagtggtc atcatgttta acccagttat
    10561 ggctcgacct cagcatccta gttcgcttat cttccctcat tttggctttg gtcaaacctt
    10621 tacagaaaaa gagttagctg actttgaaac attgccaatc gaagacttga tggtggcttt
    10681 ctttgaacga gcactagcga gagcggcaga agctggtatt gcaccagaaa atatcctgtt
    10741 ggatccagga attggctttg gtctgaccaa gaaagaaaat cttctccttt tacgggacct
    10801 ggataaacta catcagaagg gctatccaat ctttctcgga gtgtcgcgca agcgatttgt
    10861 catcaatatc cttgaagaaa gtgggtttga agtcaatcct gagacagagc ttggtttccg
    10921 aaatcgggac acggcttcgg ctcatgtaac tagtatcgct gcgagacagg gtgtagaagt
    10981 ggtgcgcgtg catgacgtag ctagtcacag gatggcagtt gaaattgcct ctgccattcg
    11041 tctggctgat gaagcggaaa atttagattt aaaacaatat aaataagatg aaagaaattg
    11101 aaaacaatca gtggattgct aactaccgga cggatcaacc gcattttggc ttggaacgaa
    11161 tggtggaact gttagctttg cgtggcaatc cccatcttaa actcaaggtt ctccatatcg
    11221 gagggactaa cggcaagggc tcgactattg cttttttgaa aaagatgcta gaaaagctag
    11281 ggctgagagt tggcgtgttt agttcgccct atctcattca ttacacagac cagattagca
    11341 tcaatgggga atcgatctca gaagcgaggc tagaagctct catggcagac tatcagtctt
    11401 tgctggaggg agaagcggtc gccaatttac agggcacaac cgagtttgag attatcacag
    11461 ccctagccta tgactacttt gcctcagagc aagtagatgt ggctatcatg gaagttggca
    11521 tgggtggact tttggatagt accaatgtct gtcagcccat tttgacagga attacaacta
    11581 ttggcttgga tcatgtggcc ctacttggtg acaccttgga ggccatagca gagcagaagg
    11641 caggtattat caaacaaggg atgcccttgg taacagggcg tattgctcca gaagccttga
    11701 ctgtgattga ccgcattgcg gaagggaaag atgcgccgag acttgcctac gggacagatt
    11761 atcaggttcg tcatcaagaa agtgtggtga caggggaagt ctttgactat acaagtgctg
    11821 tcagacaagg tcgcttccag actagcctgc ttggtttgta ccaaatagag aatgctggga
    11881 tggccatagc tttacttgat actttttgtc aagaagatgg tcgagagcta gcaagcaatg
    11941 actttcttgg tcaagccttg gaagaaacaa gttggccagg gcgtttggaa atcgtgtcaa
    12001 gagatccctt gatgattttg gatggagccc ataatcccca tgctatcaag gccttgttgg
    12061 taaccttgca agaacgtttt gcggattatc ataaggaaat cctcttcact tgtatcaaaa
    12121 ccaaagcctt gggggatatg ttggacttgc tgggagccat gccagatacc gagcttactc
    12181 taacacattt tgcggatagt cgggcgacgg atgaaagcgt gctgaaagag gcagctaagt
    12241 ctagaaatct cagctaccaa gattggcatg attttctaga gcagaatttg acagataaaa
    12301 aagaagagaa acaaacagtt aggattgtca caggttcctt gtatttcttg agccaagtga
    12361 gggcctatct gatggagagg aagaacgaga atggatacac aaaagattga agcagctgta
    12421 aaaatgatta tcgaggctgt aggagagaac gctaatcgcg agggcttgca ggaaacacct
    12481 gctcgtgtag cccgtatgta tcaagagatt ttttcaggtc ttggtcaaac agcagaggaa
    12541 catttgtcaa aatcctttga aattattgac gataatatgg tggtagaaaa ggatatcttt
    12601 ttccatacca tgtgtgaaca ccacttcttg ccattttatg gtagagcgca cattgcctac
    12661 attccagatg gtcgtgtggc aggcttgtct aagctagccc gtacggttga agtttattcg
    12721 aaaaaaccac aaattcaaga acgtttgaat atcgaagtgg ccgatgcctt gatggactat
    12781 ctaggtgcta aaggagcctt tgttgtcatt gaggcggaac atatgtgtat gagtatgcgt
    12841 ggtgttagaa aaccaggcac tgcaaccttg acgacagtag ctcgtggtct atttgaaaca
    12901 gataaggacc tccgcgacca agcttatcgt ttaatggggc tataaaaaga atccgtttca
    12961 agcggatttt tctagaaagg aatcattatg gatcaactgc agattaagga tttggaaatg
    13021 tttgcctatc atggtctttt tcctagtgag aaagaattgg ggcagaaatt tgtcgtttca
    13081 gccatcctat cctatgatat gaccaaggca gctacagact tggatttaac agcctctgtc
    13141 cattacggag aattgtgtca gcagtggacg acttggtttc aggaaacgag tgaagatttg
    13201 attgaaacgg tagcctataa actggtggaa cgtacctttg agtcttatcc tcttgtccaa
    13261 gaaatgaagt tggaactgaa aaaaccttgg gcaccggtgc atttgtcact agatacttgc
    13321 tcggtaacca ttcatcgccg caagcaacga gcctttatcg ccctaggaag caatatggga
    13381 gataaacaag caaacttgaa gcaagccatt gacaaactgc gagctcgtgg catctatatt
    13441 ctcaaagagt ccagtgtctt agcgacggag ccttggggtg gagtggagca ggatagcttt
    13501 gccaatcaag tggttgaggt ggaaacctgg ctaccagcac aagacttgtt agaaaccttg
    13561 ttagccattg agtcagagct gggacgggtg agagaagtgc attggggacc tcgtttgatt
    13621 gatttggact tgctctttgt ggaggaccag atcctttata cagacgacct catattgcct
    13681 catccttaca tagcggaacg cctttttgtc cttgagtcct tacaggaaat tgcgcctcat
    13741 tttatccatc cgatattaaa acaaccgatc cgtaacttgt atgatgcttt gaaaaaatag
    13801 aaaaactcta gttttcagtt acttgcaact gaaggctaga gtttttaaaa taggtcattt
    13861 tcttctggga ggaggatagt ttctctaccg tccatgtcta aaaccagtac tcttggggga
    13921 taacgagggt cgaaaggatg gttaaagtca aaatcaatgg ctgtagggag gtgttgactt
    13981 gaaaagtgga aggtaatctt tccttggtta ttaagcaatt gaaactcgag ttcttcttcc
    14041 aattcaaaga cattttttaa gaaatggtcg ataatatacc aaaaagagtc aatgatgtca
    14101 tcaggcaagc tggtaacaat gccaaaacta gcagaccgca tgtgggtatt ggtaaaagcc
    14161 atatctctgt ctcctttctt ttcccttatc atacagcaaa taggattaaa aatcaagaaa
    14221 aggtgatttt ttgaaaagga ttttaactac agggaaaaag aaggaaaaaa attcccaaaa
    14281 atctaccgaa gttaataggt aaattcccaa attaacttga ttatataact ttcagttatt
    14341 ttgagaagtt accgaaaaat attttttata tctattgact tttaggggtg aaatttggta
    14401 tgatagtagg cggtattgtt taccccattt gaaaggcccc ggaaccttcc aaatactttt
    14461 cgatgggaag gaacacccat caccgtaaac aaaaatcgaa ctatatatag gagaaatcat
    14521 gaacaaaaca acatttatgg ctaaaccagg ccaagttgaa cgtaaatggt acgtagttga
    14581 cgcaactgat gtaccacttg gacgtctttc tgcagtagtt gctagcgtac ttcgcggaaa
    14641 aaacaaacca acatttacac cacacactga tacaggtgac ttcgtgattg ttatcaatgc
    14701 tgaaaaagtt aaattgactg gtaaaaaagc aactgataaa atctactaca ctcactcaaa
    14761 ccacccaggt ggattgaaac aaatctctgc aggtgaactt cgttctaaaa atgcagtacg
    14821 tttgattgag aaatcagtta aaggtatgct tccacacaat acacttggac gcgctcaagg
    14881 tatgaagttg aaagtatttg ttggagctga gcacactcac gctgcacaac aaccagaagt
    14941 tcttgacatt tcaggactta tctaaggaaa ggaacaataa agtatgtcac aagcacaata
    15001 tgcaggtact ggacgtcgta aaaacgctgt tgcacgcgtt cgccttgttc caggaactgg
    15061 taaaatcact gttaacaaaa aagatgttga agagtacatc ccacacgctg accttcgtct
    15121 tgtcatcaac caaccattcg cagttacttc aactgtaggt tcatacgacg ttttcgttaa
    15181 cgttgtaggt ggtggatacg ctggtcaatc aggagctatc cgtcacggta tcgctcgtgc
    15241 ccttcttcaa gtagacccag acttccgcga ttcattgaaa cgcgcaggac ttcttacacg
    15301 tgactcacgt aaagttgaac gtaagaaacc aggtcttaag aaagctcgta aagcatcaca
    15361 atttagtaaa cgttaattcg aaagaattac tatacttata cagagcacct ttcggggtgt
    15421 tcttttttta tactttctta ctaaattggt gcaattgaca cagttgttgc gactttagtc
    15481 gcttacaaat gtggctgcaa cctgacaagg tcagttgcct caaaacgtta atcaatacaa
    15541 ttatatcaac gtttcaaagc actcaagagt ttacctcatg ggtgcttttt ttatgttttt
    15601 tgaaaaagtt cacctcaaag tttaccttat tttcacctta ttgttttaga gactgtaagg
    15661 caaattcacc gacggccata gggactacat tagaagtatt gacataaatc tgtgttgtac
    15721 ctgtgtcgct atgtattaga gcttcagaaa tggcttctaa gctcattcct gcttgtttag
    15781 cgagcgttgc tccggtatga cgtagtttgt gtggcgtagc gtgtgtaagc tctgggtgtc
    15841 gttttctgat agttttcatc ttattattga gatagtcaga atgtaaaggt ttattgatat
    15901 tgcctttggt atctatgtaa gtaaagatga attgttctgg attactgatg ataccaaact
    15961 ttgccagttc atatttttgt tgttttttcc atgaagtcag aagttgaagt aagtcattag
    16021 aaatagagaa aatgggaaat gtttccacaa taaaacgcat attatcagat ggttaatgcg
    16081 ttttatattt gggtttgagg cttataaaat aggataagcg tactgaaaac ttagatatga
    16141 caaacaaaat aaaattttta aaagctacat agaaacatgg tataatgtat ctaaaggagg
    16201 tagcatatgt ccttagatat agataaagaa aagatgacaa tcatgggaat agcttttgaa
    16261 aaccgatccg tttttaagag tgtttggtat gctttaagta caaatatgat tgaaggatgg
    16321 cgacctacgg ttagtgatgt tgaaaaatta cgagatgaag ctcttgctct ggggatgact
    16381 taatgaagcg caactgttat gaatcttatg actatgttga tccggataat ttatataccg
    16441 atccgggttc ttcagttcta agaaataagc aggaaggaaa aaagcacgcg agcttgaata
    16501 tcgtatgatt gctagtaaga gtttgaaatt atttatcaat cctatcttag ttaatagttt
    16561 aaaagtagtt tgtttcacaa ctgcataagc ttagaaaagt tgaaaagtga taactcttta
    16621 ataaactctt ggtttgttaa aagatatttt gtccactaca tttttttcaa ttgactatta
    16681 tttgtcatag atataacaga tagaacattg cattcagaat aatgaaaaac gcatcaaaaa
    16741 tggtgcgttc tgtttttatg ctaccataaa aggaggaaaa caaattgaaa atttttaagg
    16801 gagagtttta tcgaatctct gtattaacag acaagctagt aaggttagaa tactctcgaa
    16861 ctggaaattt tgaggataga acgacacaac ttatctataa tagagatttt ggccaagttt
    16921 cgttagatta tatcgagaca tcaaatgtac tagatattat gacggactat tttcatctgc
    16981 actttaataa aggagaattt aacgccgaaa atttatttat agaattaaaa ggaaattttg
    17041 ccgtatatgg tagtcgctgg tattttggtg aatctattga aacgttaaaa ggaacagctc
    17101 ggactctgga taaggcagat ggagcaatct cgttagaaga tggaattatt agccgaaatg
    17161 gtatagcctt attggatgat tctcaaggat ttatttggga tgaacaatct ggttatattg
    17221 agagagaaaa tcaaattgac ctgtatttct ttgcctatgg gcatgattat agaggagcaa
    17281 tcagagactt ttaccatttg actggttcaa cacccttgtt gccaagatat gctttaggca
    17341 attggtggag tagatattgg ccttatacgt cggatgaata cttggattta atagacagat
    17401 ttgaaacaga gaaaattcca ttatctatcg gtgtgttaga tatggattgg catataactg
    17461 acattccagc tcgttttgga agtggctgga caggatatag ttggaataga aacttaatac
    17521 caaatccaga acagttattg caacaacttc atgatagaaa gttaaaactc tccttaaatg
    17581 tccatcctgc tgatgggata cgggcttatg aagaagctta tcctcaaatc gcaaaacgat
    17641 tggggttaaa tgtagaacta gaagaacctg ctatttttga tttttttaat ccctctttta
    17701 gggaagccta ctttaaagat gttcattatg agttagaaaa gcagggagta gatttttggt
    17761 ggattgactg gcaacaaggg acacaaggta tgctagatcc actttggctt ttaaaccatt
    17821 atcactatca ggatagttgt aaaaatgcag aaggtggttt gattttatca agatatgcag
    17881 gtcctggtag tcaccgctac cctgttggtt tttcagggga tactattatt agttggaatt
    17941 ccttaagatt tcaaccctat tttacagcga cagcatctaa tatcggttat agttggtgga
    18001 gtcatgatat cggtggacat atgttggggg attatgacga agagctacaa actagatggc
    18061 tacagtttgg tgtttttagt ccgattactc gattacatag ttctagaagt ccttttaata
    18121 gtaaagaacc ttggtttttt tcagaaacaa catctaagat tatgaagaaa tacctccgtt
    18181 tgagacatca gatgattccc tatctatata ccatgaatgt aaagacacat gaggaaggtg
    18241 ccccattaat cagtccaatc tattatttct atccagagaa tgatgagagc tataatgttc
    18301 caaatcaata cttttttgga acagaactga tggtggctcc cattgtagaa aagatggatt
    18361 tgacattcca atctgcaaaa gtagatgtat ggttccctga aggtgaatgg tatgactttt
    18421 tttcagagaa aaaatacaca ggtggtgtga agttaagtgt ttatagagac atctcgacta
    18481 cgcctgtgtt tgcaaaaagt ggtgcaatca ttcccttggt tggttctgag ataggtatgg
    18541 gtgttgattt acctgaagtt gtagattggt atgtattccc aggaaaacaa cattcttttg
    18601 aaatgcttga agatcaaaat ggtcaaagat ataaaacaag attatcaatc gattgggaaa
    18661 tgggaatggt agagttagca ttacaaggag attctagtat cgttccaagc aatagaaaac
    18721 atagaattca ttttaaagga acgaatgtgt ctataattga attgccaaat aagaatgata
    18781 cagctaaatt tgaatggaaa gataataaaa ggacatcttt aaatgacgaa gtttttagac
    18841 tactaaagac agcttctctt ccatatgaat taaaagatag attgttaaat caattcatca
    18901 atgcgaaaaa ctctcatgac ttaatgaata tcttgcatca tcaggataag gaattgagag
    18961 ggcgtttgtt ggaaatgata tttactagcc aaaactaatt gaaataatta gaaagtcatt
    19021 tgtttagtgt atatgaagat tctgtatggt attcgttatc actggtcaca ttgaaaatgt
    19081 gaaataagca cctacaacat agactttaca acacttcatg ttttatatca tggggtgttt
    19141 ttctatttaa gtcaaagccc atcaaaaaat ctcactattc atcaggttaa aggaaaccta
    19201 atcatagtga gattgtgaat tatagtagag tttgtatcgc ctcttcaatt tgttttgggt
    19261 ctgtttttga agaaaagcgt tcaaagactt gcccatctcg accgatgaga aacttagaga
    19321 aattccattc gattcgtttt cctagtgggc cggatttctg gtcttttaac cagacataga
    19381 gagggtctgc ttccttaccg ttgaccttaa tcttggcaaa acgtgggaag gtggtttgaa
    19441 aatgtaggct acagaaggcg ttgatttcct ctgcgctgcc gggtgcttgt cccataaact
    19501 gattgcaagg gaaatccaat atttcgaagc cctgagcttg atagcgttca tagagttctt
    19561 gaagtccctg gtactggggc gttaaaccac atccagtagc agtgttgaca atcaagagaa
    19621 ctttgccacg atagctatcc aagggagttg cttggttgtt ttggttcaaa acggaaaaat
    19681 cataaagtga agtcatgagg gcctcttttc tttttctaca ttgtaacagt ttttactttt
    19741 ttcgtcgagt cggatggaag atattgttga agaataagtc ttcaatatga tagaaaccgt
    19801 ttacaaataa ctttaaaaat ggtatgattt aattaaaccg gtttacttag ttgctataaa
    19861 tctctaattt gagatttagt tcctattgat tttacaatat gtttattgga gtgtatacat
    19921 gcaaacaaaa acaaagaagc tcattgtgag tttgtcttca cttgttttat caggattttt
    19981 attaaaccat tatatgacag ttggagcgga agaaacgact acgaatacca ttcagcaaag
    20041 ccagaaggaa gttcagtatc agcaaaggga tacaaaaaat ttagttgaaa atggtgattt
    20101 tggtcagacg gaggacggaa gcagtccgtg gacaggaagc aaagctcagg ggtggtcagc
    20161 ttgggtagac cagaagaata gttctgcaga tgcctcaact cgagtcattg aggctaaggg
    20221 tggggctatc actatctcaa gccatgagaa attaagggca gcggttcacc gtatggttcc
    20281 tattgaagct aagaaaaagt ataaactgcg tttcaagatt aaaacagatc ataaagtcgg
    20341 gattgccaag gttcgtatca ttgaggaaag tggtaaggac aagcgattgt ggaattctgc
    20401 aacgacgtca ggaacaaagg actggcagac cattgaagca gactatagcc cgactttaga
    20461 tgttgataaa atcaagctgg agttattcta tgaaacagga actgggactg tttcctttaa
    20521 ggatattgag ctggtagagg tagcagacca gctttctgag gattctcaaa cagataaaca
    20581 gcttgaggaa aagattgatt taccaattgg aaaaaaacat gttttttctc ttgcggacta
    20641 tacttataag gtagaaaatc ctgacgttgc ttcagtcaaa aatggaattt tagaacctct
    20701 taaggaaggg acaaccaatg tcattgtcag taaagatggc aaggaagtga aaaagattcc
    20761 tttgaagatt ctagcctctg ttaaggatgc atacacagcc cgtttggatg actggaatgg
    20821 catcatcgct gggaatcaat actatgattc taaaaatgaa cagatggcca aattaaacca
    20881 ggaattggaa ggaaaggtag ctgatagcct atctagtatt tcaagtcagg cggaccgcac
    20941 ctatttgtgg gaaaaatttt caaattataa aatgtctgca aatctgactg ccacttatcg
    21001 gaaattggag gagatggcca agcaagtgac caatccttct tctcgttatt atcaagatga
    21061 aactgtcgtt cgaacagtca gggattccat ggaatggatg cataaacatg tctacaatag
    21121 tgaaaagagc attgttggga actggtggga ttatgaaatc ggtacacctc gtgccatcaa
    21181 caataccttg tctctgatga aagaatactt ctctgatgag gaaattaaaa aatatacaga
    21241 tgtgattgaa aaatttgtac cagatcccga acatttccga aagacgactg ataacccatt
    21301 taaggctcta ggtggaaact tagttgatat gggaagagta aaagtaatag ctggtttact
    21361 gcgtaaggat gatcaagaaa tttcttctac cattcgctcg attgagcaag tgttcaagtt
    21421 ggtagaccaa ggtgaaggtt tttatcaaga tggatcctat atagaccata ccaatgttgc
    21481 ctatacgggt gcttatggga atgttttgat tgatggcctg tctcaactgt tgccagtcat
    21541 tcaaaagacc aagaatccaa tcgataaaga taaaatgcaa accatgtact actggattga
    21601 taaatcgttt gctcctttgc tggtgaatgg agagctgatg gatatgagtc gtggacgctc
    21661 gatcagtcgt gcaaatagcg aggggcacgt ggccgcagta gaagtactaa gagggattca
    21721 ccgaatagcg gatatgtctg aaggagaaac caaacaacgt ttgcagagtc ttgtgaagac
    21781 cattgttcaa tcggatagtt attatgatgt ctttaagaat ttgaagactt ataaggatat
    21841 cagtttgatg caatccttgt taagtgatgc aggagtcgca agtgttccaa gaacaagtta
    21901 cctatctgcc tttaacaaga tggataaaac agccatgtac aatgcagaga aagggtttgg
    21961 atttggcttg tcactctttt ccagtcgtac cttgaattac gaacacatga acaaggaaaa
    22021 taaacgtggt tggtatacga gtgatgggat gttctatctt tacaatggcg atttgagtca
    22081 ctatagcgat ggctactggc caacagttaa tccatataag atgcctggta caacagagac
    22141 ggatgctaag agagcggata gcgatacagg taaagtttta ccgtctgctt tcgttggaac
    22201 gagcaaacta gatgatgcca atgcgacagc aaccatggat ttcaccaact ggaatcaaac
    22261 attgactgct cataagagct ggtttatgct aaaggataag atcgcctttt taggaagcaa
    22321 tatccaaaac acttcaacag atactgctgc aactacaatt gaccagagaa aactggaatc
    22381 aagtaatcca tataaagtct atgtcaatga taaagaagcc tcccttacag aacaagaaaa
    22441 ggattatcct gaaacccaaa gtgtcttttt agaatcatcc gattcgaaaa agaatattgg
    22501 ttactttttc tttaagaaga gttcaatcag tatgagtaag gctttgcaaa agggagcctg
    22561 gaaggatatc aatgaaggac agtcagacaa ggaagttgaa aatgaatttc ttacgattag
    22621 tcaggctcat aagcaaaatg gagattctta tggctatatg ctcatcccta acgtgggtcg
    22681 tgccaccttc aatcaaatga taaaagagtt agaaagtagc ctcatcgaaa ataacgaaac
    22741 ccttcagtct gtttatgatg ccaaacaagg agtttggggc attgtgaaat atgatgattc
    22801 tgtctctact atttccaacc aattccaagt tttgaaacgt ggagtctata ccattcgaaa
    22861 agaaggggat gaatataaga ttgcctacta taatcctgaa acccaggaat cagctccaga
    22921 tcaggaagtc tttaaaaagc tagagcaagc agctcagcca caagtacaga attcaaaaga
    22981 aaaggaaaaa tctgaagagg aaaagaacca ttcggatcaa aagaatctcc ctcagacagg
    23041 agaaggtcag tcaatcttgg caagtctagg gttcttgcta cttggggcgt tttatttatt
    23101 ccgtagagga aagaacaact aatttgttca tcatctagat gaattacatg aaactgtgga
    23161 aaatagaaaa aatccgaaga aggccaaata tcttcggatt tttcttttaa aaaaggataa
    23221 gttgatactt atccttttta cttcattatg tgactatagc gttttgaaac tagaatagga
    23281 catcataact gctaaaagat ttctataaat tcatttgatt ttcctaatca atttgttcgt
    23341 atcctatttc actctactat attagtccgt ctcgcacctc acggagcgag acaaaacaac
    23401 cacccgctat gcgggtgcgc gtcgaaggtt ataccaaaaa aactccaaac gcgatacaat
    23461 aaaggtgttc aacccacttg taaagcgaaa ggagaaaaaa tatggcacaa aaggctcata
    23521 gtttatctca cacaaagtgg aggtgttcta tcacattgtg ttcaccccta agtatagacg
    23581 aaaagtcatc tata
//
LOCUS       DBERCW010000032        20957 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.032, whole genome shotgun sequence.
ACCESSION   DBERCW010000032 DBERCW010000000
VERSION     DBERCW010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.032"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..437
                     /locus_tag="ACL72M_001554"
                     /pseudo
     CDS             1..437
                     /locus_tag="ACL72M_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(512..1432)
                     /gene="cysK"
                     /locus_tag="ACL72M_001555"
     CDS             complement(512..1432)
                     /gene="cysK"
                     /locus_tag="ACL72M_001555"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGS0716662.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYNGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1717..2352)
                     /locus_tag="ACL72M_001556"
     CDS             complement(1717..2352)
                     /locus_tag="ACL72M_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGS0716663.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDNGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2408..3706
                     /locus_tag="ACL72M_001557"
     CDS             2408..3706
                     /locus_tag="ACL72M_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0716664.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSNLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3703..4365
                     /locus_tag="ACL72M_001558"
     CDS             3703..4365
                     /locus_tag="ACL72M_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGS0716665.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREEGASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4445..4993
                     /gene="raiA"
                     /locus_tag="ACL72M_001559"
     CDS             4445..4993
                     /gene="raiA"
                     /locus_tag="ACL72M_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGS0716666.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5129..7102
                     /locus_tag="ACL72M_001560"
     CDS             5129..7102
                     /locus_tag="ACL72M_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGS0716667.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7099..7551
                     /gene="rplI"
                     /locus_tag="ACL72M_001561"
     CDS             7099..7551
                     /gene="rplI"
                     /locus_tag="ACL72M_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGS0716668.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7595..8947
                     /gene="dnaB"
                     /locus_tag="ACL72M_001562"
     CDS             7595..8947
                     /gene="dnaB"
                     /locus_tag="ACL72M_001562"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGS0716669.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8949..9215
                     /locus_tag="ACL72M_001563"
     CDS             8949..9215
                     /locus_tag="ACL72M_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGS0716670.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9304..10422
                     /gene="cbpD"
                     /locus_tag="ACL72M_001564"
     CDS             9304..10422
                     /gene="cbpD"
                     /locus_tag="ACL72M_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGS0716671.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTV
                     GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGLWYYLGSSGAM
                     KTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10505..10607
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10678..10968
                     /locus_tag="ACL72M_001565"
     CDS             10678..10968
                     /locus_tag="ACL72M_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGS0716672.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            10931..11689
                     /locus_tag="ACL72M_001566"
     CDS             10931..11689
                     /locus_tag="ACL72M_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716673.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            11727..12734
                     /locus_tag="ACL72M_001567"
     CDS             11727..12734
                     /locus_tag="ACL72M_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0716674.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12734..13462
                     /locus_tag="ACL72M_001568"
     CDS             12734..13462
                     /locus_tag="ACL72M_001568"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716675.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13581..14039
                     /locus_tag="ACL72M_001569"
     CDS             13581..14039
                     /locus_tag="ACL72M_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGS0716676.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            14041..16473
                     /locus_tag="ACL72M_001570"
     CDS             14041..16473
                     /locus_tag="ACL72M_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGS0716677.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            16794..17447
                     /gene="rr06"
                     /locus_tag="ACL72M_001571"
     CDS             16794..17447
                     /gene="rr06"
                     /locus_tag="ACL72M_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGS0716678.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17444..18784
                     /gene="hk06"
                     /locus_tag="ACL72M_001572"
     CDS             17444..18784
                     /gene="hk06"
                     /locus_tag="ACL72M_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGS0716679.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSRLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            18867..19394
                     /locus_tag="ACL72M_001573"
     CDS             18867..19394
                     /locus_tag="ACL72M_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGS0716680.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19473..>20957
                     /gene="pspC"
                     /locus_tag="ACL72M_001574"
     CDS             19473..>20957
                     /gene="pspC"
                     /locus_tag="ACL72M_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HGS0716681.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSEN
                     NPTVTSSGQDISKKYADEVKSHLEKILSEIQTNLDRSKHIKTVNLINKLQDIKRTYLY
                     ELNVLEDKSKAELPSKIKAELDAAFEQFKKDTLPTEPGKKVAEAKKKVEEAEKKAKAQ
                     KEEDYRNYPTITYKTLELEIAESDVKVKEAELELVKKEADESRNEGTINQAKAKVESE
                     QAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEPATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKDQKEEDHRNYPTITYKTLEL
                     EIAESDVEVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAE
                     EEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEED
                     YARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNT"
BASE COUNT         6620 a         3460 c         4772 g         6105 t
ORIGIN      
        1 aatctgaagg tacccaatta tcgccaagaa gaagattggg ctaagatggg tttaccaatc
       61 acacgcaagg aaatctctaa ttggcatatc aagacgagtc aatactattt ggagcccctc
      121 tataacctct tgcgagagag actattgact cagcccttac ttcatgcgga tgaaacttct
      181 tatagggtgc tagagagtga tagtcagctg acttactatt ggactttttt gtctgggaaa
      241 gctgagaaac aagggattac gctttaccat catgtcctaa tcgatttgtt catatcttat
      301 ttcaatccat tataaatagt gagaaatatc tatcctatct tctagaatgt cttccaaacg
      361 tggaaactct cgtaaacaaa gaggttttag aggcttattt accatggact aaaattgtac
      421 aagaaaagtg caaataagaa atctccagat taggaactat ccgtgagttc tctagtctgg
      481 agatttttca atatacttcg ttattggacg gttacaattc ataaagtgct gtagagagat
      541 aacgttcacc gttatctggt gctagggcaa ggactttttt acctgtacct aattttttgg
      601 caacctcgat ggctccgtag atagctgcag ctgaggaaat ccctacaagg aagccttctt
      661 ttccaccaat ttcacgtccg agtgcaagag cgtcatctga tgttacacga acgataccat
      721 tataggcttt agtatcaagt gtatcaggaa taaatccagc tgagatacct tgaattttgt
      781 gaggaccagg tttttcacca gatagaatag cagattcatc tgcttctact gcaaaaactt
      841 gaatgttaga attttctgat ttgagtgcat gagaaacacc agaaatcgtt ccaccggtac
      901 ctactccagc aacaaaggca tctaatccat ctttaccgaa agcagctagt atctcagctc
      961 ctgttgttct ttcgtgtact tctggattag ctggattgtc aaattgaaga ggaaggaaac
     1021 catcacgttc agcagcgatt tcttgagcct tagcaatagc acctttcatt ccctcgctac
     1081 caggagttag gacgagttca gcaccataag cttggataat tttacgtcgt tctacactca
     1141 tagtttcagg cataacgatg acgactttat accctttagc agcacctacc catgaaagtc
     1201 caataccagt gtttccactt gttgcttcaa caatagtaga accaggtttc agaataccat
     1261 cttgttcagc tttttcaatc atgctaaggg caatacggtc ttttacagat gaaccaggat
     1321 taaatgcttc aagctttata tagacgtctg cagcaccttc tggcacgatg ttgttaagtt
     1381 taacaatcgg tgtttgaccg attaattcag taatgttgtt ataaatagac atatgaatac
     1441 ctctttgtat aagatatctt tagtataacg ctatccatac catttgtaaa atatagaaat
     1501 cctatcgaag cgataggatt tctatatatc atagatcaaa gtcattaatt ttcaagtgat
     1561 tgcgttcagc taattctagt aaataggtgt gaaggaaaac gctatcaggt ttcgtttgaa
     1621 ttgcttcatt ttctagtata ttttggtacg catcttttta ttttgctcgc taaagtagtt
     1681 gtgagaatgt caacgaaacg ctgtattatt cattgtttac actaagttta caggaacttc
     1741 aacctctcgt aaaccttggt cagttaaagt gacttttcca ttaaaaaact ccacaagtgc
     1801 agctttaata gtttcttttt cttctttatc aacataaatc atcgtatcga cttgatctgt
     1861 aaagtttgta tccagctcca tgagatcatg ttctttaagg aagttactgt actcttggta
     1921 ctgagcataa gacatttgaa tagcaatgcc agcctgttct tttatttcaa taataccaat
     1981 ttctttgaca gctaaggcga cactgccggc gtaagcacga attagtcctc cagcgcctag
     2041 tttaatacca ccaaagtagc gtgtcacgac cacacagaca ttggtgagat tgtgattttc
     2101 tagtacccca agcatgggaa caccagcagt accactaggc tcaccattat cacttgtacg
     2161 tttaatttca ctacgttctc caataataaa ggcagagcag ttatgtgtcg ctttgtagtg
     2221 ttcttttttg atggcagtaa tgaagtcacg agcctcttct tcgctataaa cacgcttggc
     2281 atggcagata aagcgagatt tttttatttc ttcttggact tggccgtcct ctttaattgt
     2341 cctaaattcc atgatttaat tgtactaaaa aataatctaa agtgctagtt tttacgaata
     2401 gagaagtatg aaagtaaatt tagattatct cggtcgttta tttactgaga atgaattaac
     2461 agaagaagaa cgtcagttgg cggagaaact tccagcaatg agaaaggaga aggggaaact
     2521 tttctgtcaa cgttgtaata gtactattct agaagaatgg tatttgccca tcggtgctta
     2581 ctattgtcga gagtgcttgc tgatgaagcg agtcagaagt gatcaaactt tatactattt
     2641 tccgcaggag gattttccga agcaagatgt tctcaaatgg cgcggccaat taactccttt
     2701 tcaagagaag gtgtcagagg gactgcttca agcagtagac aagcaaaagc caaccttagt
     2761 tcatgcggta acaggagctg gaaagacaga aatgatttat caagtagtgg ctaaagtgat
     2821 caatgcgggt ggtgcagtgt gtttggctag tcctcgcata gatgtttgtt tggagctgta
     2881 caagcgcctg caacaggatt tttcttgcgg gatagctttg ctacatggag aatcggaacc
     2941 ttattttcga acaccactag ttgttgcaac aacccatcag ttattgaagt tttatcaagc
     3001 ttttgatttg ctgatagtgg atgaagtaga tgcttttcct tatgttgata atcccacgct
     3061 ttaccacgct gtcaagaata gtgtaaagga gaatggattg agaatctttt taacagcgac
     3121 ttcgaccaat gagttagata aaaaggtccg tttaggagaa ctaaaaagac tgagtttacc
     3181 gagacggttt catggaaatc cgttgattat tccaaaacca atttggttat cggattttaa
     3241 tcgctactta gacaagaatc gtttgtcacc aaagttaaag tcctatattg agaagcagag
     3301 aaagacagct tatccgttac tcatttttgc ttcagaaatt aagaaagggg agcagttaga
     3361 agaaatctta caggagcaat ttccaaatga gaaaattggc tttgtatctt ctgtaacaga
     3421 ggatcgatta gagcaagtac aagcttttcg agatggagaa ctgacaatac ttatcagtac
     3481 gacaatcttg gagcgtggag ttaccttccc ttgtgtggat gttttcgtag tagaggccaa
     3541 tcatcgtttg tttaccaagt ctaatttgat tcagattggt ggacgagttg gacgaagcat
     3601 ggatagaccg acaggagatt tgcttttctt ccatgatggg ttaaatgctt caatcaagaa
     3661 ggcgattaag gaaattcaga tgatgaataa ggaggctggt ctatgaagtg cttgttatgt
     3721 gggcagacta tgaagactgt tttaactttt agtagtctct tacttctgag gaatgatgac
     3781 tcttgtcttt gttcagactg tgattctact tttgaaagaa ttggggaaga gaactgtcca
     3841 aattgtatga aaacagagtt gtcaacaaag tgtcaagatt gtcaactttg gtgtaaagaa
     3901 ggagttgaag tcagtcatag agcgattttt acttacaatc aagctatgaa ggattttttc
     3961 agtcggtata agtttgatgg agacttcctg ttaagaaaag ttttcgcttc atttttaagt
     4021 gaggagttga aaaagtacaa agagtatcaa tttgttgtaa ttcccctaag tcctgataga
     4081 tatgctaata gaggatttaa tcaggttgag ggcttggtag aggcagcagg ctttgagtat
     4141 ctggatttat tagagaaaag agaagaggga gccagttctt ctaaaaatcg ttcagagcgc
     4201 ttggggacag aacttccttt ctttattaaa agtggagtca ctattcctaa aaaaatccta
     4261 cttatagatg atatctatac tacaggagca actataaatc gtgttaagaa actgttggaa
     4321 gaagctggtg ctaaggatgt aaaaacattt tcccttgtaa gatgaggaaa aaatttgcaa
     4381 aaatagaatg aaagcgttat aataaaatca taaaaacaaa aatgtttaga aagaaggtac
     4441 tcatatgatt aaatatagta tccgtggtga aaacctagaa gtaacagaag caattcgtga
     4501 ttatgtagtt tctaaactcg aaaagatcga aaagtacttc caaccagaac aagagttgga
     4561 tgcccgaatt aacttaaaag tttatcgtga aaaaacggct aaagtggaag taacgattcc
     4621 gcttggatct attactctcc gcgcagaaga tgtatctcaa gatatgtatg gttcaattga
     4681 ccttgtaact gataaaattg aacgtcagat tcgtaaaaat aaaacaaaaa tcgagcgtaa
     4741 aaataaaaat aaggtagcaa ctggtcaatt atttacagat gctttggtgg aagattcaaa
     4801 tgttgtccag tctaaagttg ttcgttcaaa acaaattgat ttaaaaccaa tggatttgga
     4861 agaagcaatt ctacaaatgg atttattggg gcatgatttc tttatctatg tggatgttga
     4921 agatcaaaca accaatgtga tttatcgtcg tgaggatggc gaaattggtt tgttagaggt
     4981 taaagaatct taatttcaat atgtgtaaag gtaggtttac tgaattgtaa actacctttt
     5041 tcttataatt gatagaatta ctgattacac ttttaaaaag tcgctttttg aggggtatta
     5101 tggtataatg ggtgccaaga ggttttgaat gaaaaaattt tatgtaagtc caatttttcc
     5161 tattctagta ggattgattg cgtttggagt cttatccact ttcattattt ttgttaataa
     5221 taatctgttg acggttttaa ttttgtttct ttttgtagga ggctatgttt ttttatttaa
     5281 gaaactgaga gtgcattata caaggagtga tgtagaacag atacagtatg taaaccacca
     5341 agcggaagaa agtttgacag ctctattgga acagatgcct gtaggtgtta tgaaattgaa
     5401 tttatcttct ggagaggttg agtggtttaa tccctatgct gaattgattt tgaccaagga
     5461 agatggtgat tttgatttag aagctgttca aacgattatc aaggcttcag taggaaatcc
     5521 gtctacttat gccaagcttg gtgagaagcg ttatgctgtt catatggatg cttcttccgg
     5581 tgttttgtat tttgtagatg tatccaggga acaagccata acagatgaat tggtaacaag
     5641 tcgaccagtg attgggattg tctctgtgga taattatgat gatttggagg atgcaacttc
     5701 tgagtcagat attagtcaaa tcaatagttt tgtagctaat tttatatcag agttttcaga
     5761 aaaatacatg atgttttctc gtcgggtaag tatggatcga ttttatctat ttactgacta
     5821 cacggtgctt gagggcttga tgaatgataa attttctgtt attgatgctt tcagagaaga
     5881 gtcgaaacag agacagttgc ccttgacctt aagtatggga ttttcttatg gcgatggaaa
     5941 tcatgatgag atagggaaag ttgctttgct caatttgaac ttggctgaag tacgtggtgg
     6001 cgaccaggtg gttgttaagg aaaacgacga aacgaaaaat ccagtttatt ttggtggtgg
     6061 gtctgctgct tcaatcaagc gtacacggac tcgtacgcgc gctatgatga cagctatttc
     6121 agataagatt cggagtgtag atcaggtttt tgtagtcggt cacaaaaatt tagacatgga
     6181 tgctttgggc tctgctgtag gtatgcagtt gttcgccagc aatgtgattg aaaatagcta
     6241 tgctctttat gatgaagaac aaatgtctcc agatattgaa cgagctgttt cattcataga
     6301 aaaagaagga gttacgaagt tgttgtctgt taaggatgca atggggatgg tgaccaatcg
     6361 ttctttgttg attcttgtag accattcaaa gacagcctta acattatcaa aagaatttta
     6421 tgatttattt acccaaacca ttgttattga ccaccataga agggatcagg attttccaga
     6481 taatgcggtc attacttata tcgaaagtgg tgcaagtagt gccagtgagt tggtaacgga
     6541 attgattcag ttccagaatt ctaagaaaaa tcgtttgagt cgtatgcaag caagtgtttt
     6601 gatggctggt atgatgttgg atactaaaaa tttcacctcg cgagtaacta gtcggacatt
     6661 tgatgttgct agctatctca gaacgcgcgg aagtgatagt attgctatcc aggaaatcgc
     6721 tgcgacagat tttgaagaat atcgtgaggt caatgaactt attttacagg ggcgtaaatt
     6781 aggttcagat gtactaatag cagaggctaa ggacacgaaa tgctatgata cagttgttat
     6841 tagtaaggca gcagatgcca tgttagccat gtcaggtatt gaagcgagtt ttgttcttgc
     6901 gaagaataca caaggattta tctctatctc agctcgaagt cgtagtaaac tgaatgtaca
     6961 acggattatg gaagagttag gcggtggagg ccactttaat ttggcagcag ctcaaattaa
     7021 agatgtaacc ttgtcagaag caggtgaaaa actgacagaa attgtattaa atgaaataaa
     7081 ggaaaaggag aaagaagaat gaaagtaatc tttttagcag atgttaaagg aaaaggtaaa
     7141 aaaggcgaaa ttaaggaagt accaacaggg tatgcgcaaa actttcttat caaaaagaat
     7201 ctagccaaag aagcgactgc tcaagctgta ggtgaacttc gtggtaaaca aaaatcggaa
     7261 gaaaaagctc acgctgagat gattgcagaa ggaaaagcaa ttaaagcaca acttgaagca
     7321 gaagaaactg ttgtagaatt tgttgaaaaa gttggtccag atggtcgtac ctttggttct
     7381 attaccaata agaagattgc agaagaattg caaaagcaat ttggaattaa gattgataaa
     7441 cgtcatattc aagtacaagc tccgattcga gcggttggtt tgattgatgt gccagtgaaa
     7501 atctatcaag atatcacaag tgtaatcaat cttcgtgtga aagaaggata agtttacacc
     7561 ttcttgacaa gattgtaaaa ggaagggaag tctgatggca gaagtagaag agttacgagt
     7621 acaacctcaa gatatcttag ctgagcaatc cgttttaggg gctatcttta ttgatgagag
     7681 taaacttgtt tttgtgcgag aatacattga gtctcgggac ttttttaagt atgcccatcg
     7741 tttgattttc caagccatgg tcgatttatc cgatcgtggt gatgccatag atgcaacaac
     7801 ggttcgtact atccttgata atcaaggtga tttacagaat attggtggct tgtcttactt
     7861 ggttgagatt gttaattctg tgccaacttc tgctaatgcg gagtattatg ctaagattgt
     7921 tgcagaaaaa gcaatgctac gtcgtttaat tgccaagttg acagagtctg tcaaccaagc
     7981 ttacgaagcg tcacaaccag ctgatgaaat tattgctcag gcagaaaaag ggctgattga
     8041 tgtcagtgaa aatgcaaatc gaagcgggtt taagaacatt cgagatgtgt tgaatctcaa
     8101 ctttggaaat ctggaagctc gctcgcaaca aacgaccgat attacaggta ttgcgacagg
     8161 ttatcgtgat ttggatcata tgacaacagg acttcatgag gaggagttga ttatcttagc
     8221 agctcgtcca gcagttggta agacagcatt tgccttgaat atcgctcaga acattgggac
     8281 taagttggac aaaacggttg ctattttttc actcgaaatg ggtgcggaaa gcttggtaga
     8341 tcgtatgtta gctgcagaag gcttggtgga gtcacattct atccgtacag ggcaattgac
     8401 agatgaggag tggcaaaaat atactattgc tcagggtaat ctagctaacg ccagtatcta
     8461 tatcgatgat acgccaggta ttcggattac agagattcgt tctcgttctc gtaaattggc
     8521 tcaagaaact ggaaatcttg gtttgatttt gatagactat ttacaactta tcacgggaac
     8581 tggtcgagaa aatcgtcaac aagaagtttc tgaaatttct cgtcagttga aaatactagc
     8641 caaggaattg aaggttccag taatcgctct gagtcagctt tctcgtggtg tagaacaacg
     8701 tcaggacaag agaccggtct tgtctgatat tcgtgaatct gggtctattg agcaggacgc
     8761 tgatatcgta gcttttctct atcgcgatga ctactatgaa cgtggtggtg aagaagagga
     8821 gggtatccca aataataagg tggaagttat tatcgagaaa aaccgtagtg gagctcgtgg
     8881 aacagtggaa ttgattttcc aaaaagaata caataaattt tcaagtatct caaagaggga
     8941 ggcataagat gtcagatgca tttacagatg tagccaagat gaaaaaaatc aaagaagaaa
     9001 tcaaggcaca tgagggacaa gtcgtagaaa tgactttgga gaatggtcgt aagcgccaaa
     9061 aaaatagatt gggtaagcta attgaagttt atccatccct atttattgtg gagtttgggg
     9121 atgtggaagg agataaacaa gttaatgttt acgttgaatc ctttacttac tcagatattc
     9181 ttacagaaaa gaatttgatt cattatcttg actaaagtga gaaattttct cactttttct
     9241 tttttctccg aataatttag gtgaaggcaa tcatcgcttt atattatttt tcaaggagga
     9301 agaatgaaaa ttttaccgtt tatagcaaga ggaacaagtt attacttgaa gatgtcagtt
     9361 aaaaagcttg ttcctttttt agtagtagga ttgatgctag cagctggtga tagtgtctat
     9421 gcctattccg gaggaaatgg atcgattgcg cgtggggatg attatcctgc ttattataaa
     9481 aatgggagcc aggagattga tcagtggcgc atgtattctc gtcagtgtac ttcttttgta
     9541 gcctttcgtt tgagtaatgt caatggtttt gaaattccgg cagcttatgg aaatgcgaat
     9601 gaatggggac atcgtgctcg tcgggaaggt tatcgtgtag ataatacacc gacgattggt
     9661 tccattactt ggtctactgc aggaacttat ggtcatgttg cctgggtgtc aaatgtaatg
     9721 ggagatcaga ttgagattga ggaatataac tatggttata cagaatccta taataaacga
     9781 attataaaag caaacacgat gacaggattt attcatttta aagatttgga tggtggcagt
     9841 gttgggaata gtcaatcctc aacttcaaca ggcggaactc attattttaa gaccaagtct
     9901 gctattaaaa ctgaacccct agttagtgca actgtgattg attactatta tcctggagag
     9961 aaggttcatt atgatcaaat tctcgaaaaa gacggctaca agtggttgag ttatacggct
    10021 tataacggaa gtcgtcgcta tatacagcta gagggagtga cttcttcaca aaattatcag
    10081 aatcaatcag gaaatatctc tagctatgga tccaataata gttcaactgt cggttggaag
    10141 aaaataaatg gtagttggta tcatttcaaa tcaaatggtt ctaaatcaac aggatggctg
    10201 aaagacggtt ctagctggta ttatttgaaa ttatctggtg aaatgcagac aggatggtta
    10261 aaggaaaatg gtttgtggta ttatctgggt agttcagggg caatgaaaac aggctggtac
    10321 caggtctctg gtaagtggta ttattcttac tcttcaggcg ccttagctgt taatacgacg
    10381 gtggatggct acagagtaaa cagtgatgga gaacgagtat agaaaattgg agtaggagaa
    10441 atttcctgct cttttctgta agcagtttcc ttgacatttt tcttattttg cgctatcata
    10501 tatacatata atatatggga gtctgtgtac agtctgagag gaagtgttaa acttcgaccg
    10561 cacctgatct gggtaatgcc agcggaggga acgatactta gtctaatttt gcaccttttc
    10621 catgtatggt aaaggttttt ctttttttta aaaggaaaac gagaagagga ggttcttatg
    10681 aaagcaagca ttgccttgca agttttaccc ctagcacagg ggattgatcg gatagctgtt
    10741 attgatcagg tcattgctta tctgcaaact caagaagtga cgatggtagt gacaccattt
    10801 gaaacggtct tggaagggga gtttgatgag cttatgcgca ttctaaaaga agcgctggaa
    10861 gtggcagggc aggaggcaga caatgtcttt gccaatgtca aaataaatgt aggagagatt
    10921 ttaagtattg atgagaaact tgaaaagtat actgagacga cacattagtc tattgggctt
    10981 tctcggagta ttgtcaatct ggcagttagc aggttttctt aaacttctcc ccaagtttat
    11041 cctgccgaca cctcttgaaa ttctccagcc ctttgttcgt gacagagaat ttctctggca
    11101 ccatagctgg gcgaccttga gagtggcttt actggggctg attttgggag ttttgattgc
    11161 ctgtcttatg gctgtgctca tggatagttt gacttggctc aatgacctga tttaccctat
    11221 gatggtggtc attcagacca ttccgaccat tgccatagct cctatcctgg ttttgtggct
    11281 gggttatggg attttgccca agattgtctt gattatctta acaacaacct ttcccatcat
    11341 cgttagtatt ttggacggtt ttaggcattg cgacaaggat atgctgactt tgtttagtct
    11401 gatgcgagca aacccttggc aaatcctgtg gcattttaaa atcccggtta gcctgcctta
    11461 cttttatgca ggtctgaggg tcagtgtctc ctacgccttt atcacaactg tggtatctga
    11521 gtggttggga ggttttgaag gtcttggtgt ttatatgatt cagtctaaaa aactgtttca
    11581 gtatgatacc atgtttgcca ttattattct ggtgtcgatt atcagtcttt tgggtatgaa
    11641 gctggtcgat atcagtgaaa aatatgtgat taaatggaaa cgtacttaaa atagagcgtt
    11701 tttgaaaaag aaaagaggaa atcaaaatga agaaaacatg gaaagtgttt ttaacgcttg
    11761 taacagctct tgtagctgtt gtgcttgtgg cctgtggtca aggaactgct tctaaagaca
    11821 acaaagaggc agaacttaag aaggttgact ttatcctaga ctggacacca aataccaacc
    11881 acacagggct ttatgttgcc aaggaaaaag gttatttcaa agaagctgga gtggatgttg
    11941 atttgaaatt gccaccagaa gaaagttctt ctgacttggt tatcaacgga aaggcaccat
    12001 ttgcagtgta tttccaagac tacatggcta agaaattgga aaaaggagca ggaatcactg
    12061 ccgttgcagc tattgttgaa cacaatacat caggaatcat ctctcgtaaa tctgataatg
    12121 taagcagtcc aaaagacttg gttggtaaga aatatgggac atggaatgac ccaactgaac
    12181 ttgctatgtt gaaaaccttg gtagaatctc aaggtggaga ctttgagaag gttgaaaaag
    12241 taccaaataa cgactcaaac tcaatcacac cgattgccaa tggcgtcttt gatactgctt
    12301 ggatttacta cggttgggat ggtatccttg ctaaatctca aggtgtagat gctaacttca
    12361 tgtacttgaa agactatgtc aaggagtttg actactattc accagttatc atcgcaaaca
    12421 acgactatct gaaagataac aaagaagaag ctcgcaaagt catccaagcc atcaaaaaag
    12481 gctaccaata tgccatggaa catccagaag aagctgcaga tattctcatc aagaatgcac
    12541 ctgaactcaa ggaaaaacgt gactttgtca tcgaatctca aaaatacttg tcaaaagaat
    12601 acgcaagcga caaggaaaaa tggggtcaat ttgacgcagc tcgctggaat gctttctaca
    12661 aatgggataa agaaaatggt atccttaaag aagacttgac agacaaaggc ttcaccaacg
    12721 aatttgtgaa ataatgacag aaattagact agagcacgtc agttatgcct atggtcagga
    12781 gaggatttta gaggatatca acctacaggt gacttcaggc gaagtggttt ccatcctagg
    12841 cccaagtggt gttggaaaga ccaccctctt taatctaatc gctgggattt tagaagttca
    12901 gtcagggaga attgtccttg atggtgaaga aaatcccaag gggcgcgtga gttatatgtt
    12961 gcaaaaggat ctgctcttgg agcacaagac ggtgcttgga aatatcattc tgcccctctt
    13021 gattcaaaag gtggataagg cagaagctat ttcccgagcg gataaaattc ttgcgacctt
    13081 ccagctgaca gctgtaagag acaagtatcc tcatgaactt agcggtggga tgcgccagcg
    13141 tgtagcctta ctccggacct acctttttgg gcacaagctc tttctcttag atgaggcctt
    13201 tagcgccttg gatgagatga caaagatgga actccacgct tggtatcttg agattcacaa
    13261 gcagttgcag ctaacaaccc tgatcatcac gcatagtatt gaggaggccc tcaatctcag
    13321 cgaccgcatc tatatcttga aaaatcgccc tgggcagatt gtttcagaaa ttaaactaga
    13381 ttggtctgaa gatgaggaca aggaagtcca aaagattgcc tacaaacgtc aaatcttggc
    13441 agaattaggc ttagataagt agaaaaatag ggagttggtg aagattatcc tttaccagcg
    13501 ccctttttct tttaaaaatg agaaaatttc ggtataatag tcaaacaagg tcaaggttta
    13561 aagagagagg tgggtttgtt atgagattta aaaatacatc ggatcatatt gaggcctaca
    13621 tcaaggcgat tttagatcaa tctggtatcg tggagttgca acggagtcag ttggcagata
    13681 cctttcaggt tgttcctagt cagattaact acgtgatcaa gacacgcttt acggaaagta
    13741 gaggctactt ggttgaaagt aagcgtggtg gcggaggcta cattcgtata ggacggattg
    13801 agttttctag tcatcatgaa atgctccggg agctgcttta ctcgattggt gagcgagtca
    13861 gtcaagaaat ttatgaggat attctccagc ttttggttga gcaggaattg atgaccaagc
    13921 aggagatgaa tttgctagaa tcagtagctt tggatcgcgt tttaggagaa gaagctccag
    13981 ttgttcgagc aaacatgcta cgtcagatca tacaagaggt agatagaaaa gggaagtaag
    14041 atgaactatt caaaagcatt gaatgaatgt atcgaaagtg cctacatggt tgctggacat
    14101 tttggagctc gttatctaga gtcttggcac ttgttgattg ccatgtctaa tcacagttat
    14161 agtgtagcag gggcaacttt aaatgattat ccgtatgaga tggaccgttt agaagaggtg
    14221 gctttggaac tgactgaaac ggactatagc caggatgaaa cctttacgga attgccgttc
    14281 tcccgtcgtt tgcaggttct ttttgacgaa gcagagtatg tagcgtcagt ggtccatgct
    14341 aaggtgctag ggacagagca cgtcctctat gcgattttgc atgatggcaa tgccttggcg
    14401 actcgtatct tggagagggc tggattttct tatgaagaca agaaagatca ggtcaagatt
    14461 gctgctcttc gtcgaaattt agaagaacgg gcaggctgga ctcgtgaaga tctcaaggct
    14521 ttacgccaac gccatcgtac agtagctgac aagcaaaatt ctatggccaa tatgatgggc
    14581 atgccgcaga ctcctagtgg tggtctcgag gactatacgc atgatttgac agagcaagcg
    14641 cgttctggca agttagaacc agtcatcggt cgggacaagg aaatctcacg tatgattcaa
    14701 atcttgagcc ggaagactaa gaacaaccct gtcttggttg gggatgctgg tgtcgggaaa
    14761 acagctctgg cgcttggtct tgcccagcgt attgctagtg gtgacgtgcc tgcggaaatg
    14821 gctaagatgc gcgtgttaga acttgatttg atgaatgtcg ttgcagggac acgcttccgt
    14881 ggtgactttg aagaacgcat gaataatatc atcaaggata ttgaagaaga tggccaagtc
    14941 atcctcttta tcgatgaact ccacaccatc atgggttctg gtagcggaat tgattcgact
    15001 ctggatgcgg ccaatatctt gaaaccagcc ttggcgcgtg gaactttgag aacggttggt
    15061 gccaccactc aggaagaata tcaaaaacat atcgaaaaag atgcggcact ttctcgtcgt
    15121 ttcgctaaag tgacgattga agaaccaagt gtggcagata gtatgactat tttacaaggt
    15181 ttgaaggcga cttatgagaa acatcaccgt gtacaaatca cagatgaagc ggttgaaaca
    15241 gcggttaaga tggctcatcg ttatttaacc agtcgtcact tgccagactc tgctatcgat
    15301 ctcttggatg aggcggcagc aacagtgcaa aataaatcaa agcatgtaaa agcagacgat
    15361 tctgacttga gtccagctga caaggccttg atggatggca agtggaaaca ggcagcccag
    15421 ctaatcgcaa aagaagagga agtgcctgtc tataaagact tggtgacaga gtctgatatt
    15481 ttgaccacct tgagtcgctt gtcaggtatc cccgttcaaa aactgactca gactgatgcc
    15541 aagaaatact taaacttgga agctgaactg cacaaacgtg tcatcggtca agaccaagct
    15601 gtttcaagta ttagtcgtgc cattcgccgc aatcagtcag gaattcgcag tcacaagcgt
    15661 ccgatcggtt cctttatgtt cctaggaccc acaggtgtcg gtaagaccga gttggccaag
    15721 gctttggcag aagttctctt tgatgacgaa tcagccctta tccgctttga tatgagtgag
    15781 tatatggaga aattcgcagc cagccgtcta aatggagctc ctccaggcta tgtgggttac
    15841 gaagaaggtg gggagttgac agagaaggtt cgcaataaac cctattccgt tctcctcttt
    15901 gatgaggtag agaaggccca tccagatatc tttaatgttc tcttgcaggt tctggatgac
    15961 ggtgtcttga cagatagcaa gggacgcaag gtcgattttt caaataccat tatcattatg
    16021 acatcgaact taggtgcgac tgcccttcgt gatgataaga ctgttggttt tggggctaag
    16081 gatattcgtt ttgaccagga aaatatggaa aaacgcatgt ttgaagaact gaaaaaagct
    16141 tatagaccgg aattcatcaa ccgtattgat gagaaggtgg tcttccatag cctatctagt
    16201 gaccatatgc aggaagtggt gaagattatg gtcaagcctt tagtggcaag tttggctgaa
    16261 aaaggcattg acttgaaatt acaagcttca gctctgaaat tgttagcaaa tcaaggatat
    16321 gacccagaga tgggagctcg cccacttcgc agaaccctgc aaacagaagt ggaggacaag
    16381 ttggcagaac ttcttctcaa gggagattta gtggcaggca gcacacttaa gattggtgtc
    16441 aaagcaggcc agttaaaatt tgatattgca taaaagaata aaagtaccag catctgacca
    16501 taagtcacag tggagtgaaa ctcaatgaaa atcaaagagc aaactaggca gctagccgca
    16561 ggttgctcaa aacactgttt tgaggttgca gatagagctg acgtggtttg aagagatttt
    16621 tgaagagtat aagctgcaag atgaatgatt ttcttgtatt gacgttgttg ttgacaaaaa
    16681 gtagcggata aatgaaatcc attccattat catagatgat aggctggtag gaaattttca
    16741 aatagcatac agaaaataga tgtatggagt tctggtagta gaaagggaga gagatgaaca
    16801 ttttagttgc agatgacgag gaaatgatta gagaaggaat tgcagcattt ctgacagaag
    16861 agggttatca tgtcattatg gctaaggatg gacaagaggt cttggaaaaa tttcaagatc
    16921 tccctatcca tctcatggta ctggatttaa tgatgcctag gaagagtggt tttgaagtgt
    16981 taaaagaaat caatcaaaag cacgatattc ctgtcatcgt cttgagtgct ctgggagatg
    17041 aaactactca gtcacaggta tttgatctct atgctgatga tcatgtgaca aaaccttttt
    17101 ctttggtact gcttgtcaag cgtattaagg cgcttatcag acgttactac gtcatagagg
    17161 atctttggcg atatcaggat gtaacagtgg attttacctc ttacaaagca cattataaaa
    17221 atgaagaaat tgatctcaaa ccaaaggaat tactggtact aaagtgtttg attcagcata
    17281 aaaatcaagt tttaagtaga gagcagatat tggaagaaat ttcaaaagat gtagctgatt
    17341 taccttgtga tagggtcgtt gatgtctata ttcgtactct tcgcaaaaaa ttagctttag
    17401 attgtatcgt gactgtgaaa aatgttgggt ataagattag cttatgataa aaaatcctaa
    17461 attattaacc aagtcttttt taagaagttt tgcaattcta ggtggtgttg gtctagtcat
    17521 tcatatagct atttatttga cctttccttt ttattatatt caactggagg gggaaaagtt
    17581 taatgagagc gcaagagtgt ttacggagta tttaaagact aagacatctg atgaaattcc
    17641 aagcttactc cagtcttatt caaagtcctt gaccatatct gctcacctta aaagagatat
    17701 tgtagataag cggctccctc ttgtgcatga cttggatatt aaagatggaa agctatcaaa
    17761 ttatatcgtg atgttagata tgtctgttag tacagcagat ggtaaacagg taaccgtgca
    17821 atttgttcac ggggtggatg tctacaaaga agcaaagaat attttgcttt tgtatctccc
    17881 atatacattt ttggttacaa ttgctttttc ctttgttttt tcttattttt atactaaacg
    17941 cttgctcaat cctctttttt acatttcaga agtgactagt aaaatgcaag atttggatga
    18001 caatattcgt tttgatgaaa gtaggaaaga tgaagttggt gaagttggtg aagttggaaa
    18061 acagattaat ggtatgtatg agcacttgtt gaaggttatt catgagttgg aaagtcgtaa
    18121 tgagcaaatt gtaaaattgc aaaatcaaaa ggtttccttt gtccgtggag catcacatga
    18181 gttgaaaacc cctttagcca gtcttagaat tatcctagag aatatgcagc ataatattgg
    18241 agattacaaa gatcatccaa aatatattgc aaagagtata aataagattg accagatgag
    18301 ccgcttattg gaagaagtac tggagtcttc taaattccaa gagtggacag agtgtcgtga
    18361 gaccttgact gttaagccag ttttagtaga tattttatca cgttatcaag aattagctca
    18421 ttcaataggt gttacaattg aaaatcaatt gacagatgct accagggtcg tcatgagtct
    18481 tagggcattg gataaggttt tgacaaacct gattagtaat gcaattaaat attcagataa
    18541 aaatgggcgc gtaatcatat ccgagcaaga tggctatctc tctatcaaaa atacatgtgc
    18601 gcctctaagt gatcaagaac tagaacattt atttgatata ttctatcatt ctcaaatcgt
    18661 gacagataag gatgaaagtt ctggtttggg tctttacatt gtgaataata ttttagaaag
    18721 ctatcaaatg gactatagtt ttctccctta tgaacacggt atggaattta agattagctt
    18781 gtagacagat tagtttttta ttaaagttca tatagggtta acataagtgt gttattcttt
    18841 gtgtagataa aagaaaggat actaatatgg tattagcgat tattttagta acattcttta
    18901 ttcgattgat ttttttaaag cgttcgatag agaatgagaa acgaatcctt agcaatggcg
    18961 ggaaagaatt tggagttgag aatacaaaac gattaactat ggctcatatt gttttttatc
    19021 tctcttgctt ggttgaggca atggtgcaca agacaatttt tgatggcatg ggcatggttg
    19081 gtttggtctt gcttattttt tctatgctga tgttgatgtt ggtgattcac ttgttgggag
    19141 atatttggac agtgaagctt atgcttgtca ataatcacaa atatgtagat catatcttgt
    19201 ttaggacagt aaaacaccct aattactttt taaatatttt acctgagttg attggcttga
    19261 ccttgttgag tcatgcttat gtgacttttg ttttagtttt tccagtttat gcagttattt
    19321 tgtatcgacg aatagctgaa gaggaaaagc tattacatga agttataatc ccaaatggaa
    19381 gcataaagag ataaatacaa aattcgattt atatacagtt catattgaag tgatatagta
    19441 aggttaaaga aaaaatatag aaggaaataa acatgtttgc atcaaaaagc gaaagaaaag
    19501 tacattattc aattcgtaaa tttagtattg gagtagctag tgtagtagtt gctagcttgt
    19561 tcttaggagg agtagtccat gcagaagggg ttagaagtga gaataacccc acggttacat
    19621 ctagtgggca agatatatcg aagaagtatg ctgatgaagt caagtcacat ctagaaaaaa
    19681 tattgagtga gatccaaaca aatttagata gaagtaaaca tatcaaaact gtaaatctaa
    19741 ttaacaaatt gcaagacatt aagagaacgt atttgtatga attaaatgtt ttagaagata
    19801 agtcgaaagc tgagttgccg tcaaaaataa aagcagagtt agacgcagct tttgagcagt
    19861 ttaaaaaaga tacattacca acagaaccag gaaaaaaggt agcagaagct aagaagaagg
    19921 ttgaagaagc tgagaaaaaa gccaaggctc aaaaagaaga agattaccgt aactacccaa
    19981 ccattactta caaaacgctt gaacttgaaa ttgctgagtc cgatgtgaaa gttaaagaag
    20041 cggagcttga actagtaaaa aaggaagctg acgaatctcg aaacgagggc acaattaacc
    20101 aagcaaaagc gaaagttgag agtgaacaag ctgaggctac aaggttaaaa aaaatcaaga
    20161 cagatcgtga aaaagcagaa gaagaagcta aacgaagagc agatgctaaa gagcaagatg
    20221 aatcaaagag gcgaaagagt cgggtaaaac gaggagatct tggagagcca gcaacacctg
    20281 ataaaaaaga aaatgatgcg aagtcttcag attctagcgt aggtgaagaa actcttccaa
    20341 gcccatccct gaaaccagga aaaaaggtag cagaagctga gaagaaggtt gaagaagctg
    20401 agaaaaaagc caaggatcaa aaagaagaag atcaccgtaa ctacccaacc attacttaca
    20461 aaacgcttga acttgaaatt gctgagtccg atgtggaagt taaaaaagcg gagcttgaac
    20521 tagtaaaaga ggaagctaag ggatctcgaa acgaggaaaa agttaagcaa gcaaaagcgg
    20581 aagttgagag taaaaaagct gaggctacaa ggttagaaaa aatcaagaca gatcgtaaaa
    20641 aagcagaaga agaagctaaa cgaaaagcag cagaagaaga taaagttaaa gaaaaaccag
    20701 ctgaacaacc acaaccagcg ccggctcctc aaccagaaaa accagctcca gctccaaaac
    20761 cagagaatcc agctgaacaa ccaaaagcag aaaaaccagc tgatcaacaa gctgaagaag
    20821 actatgctcg tagatcagaa gaagaatata atcgcttgac tcaacagcaa ccgccaaaaa
    20881 ctgaaaaacc agcacaacca tctactccaa aaacaggctg gaaacaagaa aacggtatgt
    20941 ggtacttcta caatact
//
LOCUS       DBERCW010000033        19692 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.033, whole genome shotgun sequence.
ACCESSION   DBERCW010000033 DBERCW010000000
VERSION     DBERCW010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.033"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            277..1137
                     /gene="speE"
                     /locus_tag="ACL72M_001575"
     CDS             277..1137
                     /gene="speE"
                     /locus_tag="ACL72M_001575"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGS0716682.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            1134..2393
                     /locus_tag="ACL72M_001576"
     CDS             1134..2393
                     /locus_tag="ACL72M_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGS0716683.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            2393..3520
                     /gene="nspC"
                     /locus_tag="ACL72M_001577"
     CDS             2393..3520
                     /gene="nspC"
                     /locus_tag="ACL72M_001577"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGS0716684.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            3517..4602
                     /gene="aguA"
                     /locus_tag="ACL72M_001578"
     CDS             3517..4602
                     /gene="aguA"
                     /locus_tag="ACL72M_001578"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGS0716685.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            4612..5487
                     /gene="aguB"
                     /locus_tag="ACL72M_001579"
     CDS             4612..5487
                     /gene="aguB"
                     /locus_tag="ACL72M_001579"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGS0716686.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGGVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(5668..6477)
                     /locus_tag="ACL72M_001580"
     CDS             complement(5668..6477)
                     /locus_tag="ACL72M_001580"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0716687.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            6749..6970
                     /locus_tag="ACL72M_001581"
     CDS             6749..6970
                     /locus_tag="ACL72M_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGS0716688.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCSRGTYDLGYIGGGNHLCKGSAARF"
     gene            7024..7695
                     /locus_tag="ACL72M_001582"
     CDS             7024..7695
                     /locus_tag="ACL72M_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0716689.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(7747..7944)
                     /locus_tag="ACL72M_001583"
     CDS             complement(7747..7944)
                     /locus_tag="ACL72M_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS0716690.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            7937..8845
                     /locus_tag="ACL72M_001584"
     CDS             7937..8845
                     /locus_tag="ACL72M_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS0716691.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            8842..9303
                     /gene="lspA"
                     /locus_tag="ACL72M_001585"
     CDS             8842..9303
                     /gene="lspA"
                     /locus_tag="ACL72M_001585"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGS0716692.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            9293..10180
                     /locus_tag="ACL72M_001586"
     CDS             9293..10180
                     /locus_tag="ACL72M_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0716693.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            10183..12066
                     /gene="cbpE"
                     /locus_tag="ACL72M_001587"
                     /gene_synonym="pce"
     CDS             10183..12066
                     /gene="cbpE"
                     /locus_tag="ACL72M_001587"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGS0716694.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVARHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            12167..13276
                     /gene="proB"
                     /locus_tag="ACL72M_001588"
     CDS             12167..13276
                     /gene="proB"
                     /locus_tag="ACL72M_001588"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGS0716695.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            13286..14548
                     /locus_tag="ACL72M_001589"
     CDS             13286..14548
                     /locus_tag="ACL72M_001589"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGS0716696.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            14552..15349
                     /gene="proC"
                     /locus_tag="ACL72M_001590"
     CDS             14552..15349
                     /gene="proC"
                     /locus_tag="ACL72M_001590"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGS0716697.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            15465..16103
                     /gene="tmk"
                     /locus_tag="ACL72M_001591"
     CDS             15465..16103
                     /gene="tmk"
                     /locus_tag="ACL72M_001591"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGS0716698.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK"
     gene            16100..16990
                     /locus_tag="ACL72M_001592"
     CDS             16100..16990
                     /locus_tag="ACL72M_001592"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGS0716699.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            17030..17347
                     /gene="yabA"
                     /locus_tag="ACL72M_001593"
     CDS             17030..17347
                     /gene="yabA"
                     /locus_tag="ACL72M_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGS0716700.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            17350..18219
                     /gene="rsmI"
                     /locus_tag="ACL72M_001594"
     CDS             17350..18219
                     /gene="rsmI"
                     /locus_tag="ACL72M_001594"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGS0716701.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            18281..18409
                     /locus_tag="ACL72M_001595"
                     /pseudo
     CDS             18281..18409
                     /locus_tag="ACL72M_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            18446..18964
                     /locus_tag="ACL72M_001596"
     CDS             18446..18964
                     /locus_tag="ACL72M_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGS0716702.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            19073..19692
                     /locus_tag="ACL72M_001597"
                     /pseudo
     CDS             19073..19692
                     /locus_tag="ACL72M_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
BASE COUNT         5955 a         3489 c         4545 g         5703 t
ORIGIN      
        1 atcaatgccc acataaagca tgggagtacc tccagatgta gtatttcaag tctacttggt
       61 tatccacgaa ttttttgcct tgttacctta gacgagataa aacgtctatg cgttatcaaa
      121 ctcattacca attgaaacaa aaaactgtgg ttagagcctt tcggaaatcg tcaagcgatt
      181 ggagggaata aactaatcca cagtggctta ttccaagtat accacttggg ctttggcagt
      241 agctaactgc gctaaatata atataaggag aaatagatgg atttatggtt ttctgaagtt
      301 catactccag atgtcaaatt gtctctgaga acagccaagc aactttacgc tggaaaaagt
      361 gaatggcagg atatcgaagt cttggatacg ccagcttttg ggaaaatact gattttaaat
      421 ggccatgtct tgttctcaga tgcggatgat ttcgtctaca atgaaatgac cgttcacgtt
      481 cccatggctg tccacccaaa tccaaagaaa gtattggtta ttgggggtgg tgacggcggt
      541 gttgcccaag tattaacact ctatcctgaa ctggaacaaa tcgatatcgt ggaaccggat
      601 gagatgttgg tcgaggtctg tcgtgagtat ttcccagact ttgctgcagg gctagatgat
      661 cctcgtgtta ccatttacta ccaaaatggg ctacgctttt tgcgaaactg cgaagatgat
      721 tacgatatta tcatcaacga tgcgacagat ccatttggcc atacggaagg actctttacc
      781 aaggaattct acggcaatag ttatcgagct ctgaaggaag acggcatcat gatttaccag
      841 catgggagtc ccttctttga cgaggatgag tcggcctgcc gaagcatgca ccgcaaggtc
      901 aatcaagcct ttccaatcag tcgggtttat caggcccata ttccaactag cccagctggc
      961 tattggttgt ttggatttgc atcgaaaaaa taccaccctg tcaaagattt tgacaaggaa
     1021 ggttggaaaa aacgccagct tttcacagaa tactacactg caaacttaca cgtgggatcc
     1081 tttatgttgc ccaagtatgt tgaggacatt ttagaagaag aggaaggaaa aaaatgagtc
     1141 gtttactagt tattggttgt gggggcgttg cccaagttgc tatttcaaag atttgtcaag
     1201 atagcgaaac atttacagag attatgattg ctagccgtac caagtcaaaa tgcgatgact
     1261 tgaaagcgaa gctagaaggc aaaacaagta ctaaaattga aactgcagca cttgatgctg
     1321 acaaggttga agaagtgatt gccctgattg aaagctacaa accagaagct gttttgaatg
     1381 tagctctgcc ttatcaagat ttaaccatta tggatgcttg tttggcaaca ggtgttcact
     1441 atatcgatac agccaactac gaagcagaag acacagaaga ccctgagtgg cgtgctatct
     1501 acgaaaaacg ttgtaaggaa cttggtttta cagcctactt tgactactca tggcagtggg
     1561 cttatcaaga gaaattcaaa gaagcaggct tgactgctct tcttggttct ggttttgacc
     1621 caggtgtaac tagtgtcttt tcagcttatg ccctcaaaca ctattttgat gaaatccatt
     1681 atatcgacat tttagactgt aatggcggtg accacggtta tccatttgca accaacttta
     1741 atccagaaat taatctccgt gaggtttctg cgccaggttc ttactgggaa gatgggaaat
     1801 gggtcgaagt cgaagctatg tctatcaagc gtgagtatga tttccctcaa gttggacaaa
     1861 aagatatgta tctccttcac catgaagaaa tcgaatcatt ggccaagaac attccaggtg
     1921 tcaaacgcat tcgtttcttt atgacttttg gtcaatctta cttgacgcac atgaaatgtc
     1981 ttgaaaatgt tggactcctt cgtacggata ccattaactt taacggccaa gaaattgttc
     2041 caattcaatt tttgaaagcc ttgcttccag atcctgctag ccttggccca cgtactgtag
     2101 gtaaaaccaa tattggatgt atctttacag gtgtcaaaga tggcgttgaa aagactatct
     2161 acatctacaa tgtttgcgac catcaagagt gctatgcaga agtcgggtca caagcaattt
     2221 catacacgac aggcgttcca gccatgattg ggacaaaatt agtcatgaac ggaacttgga
     2281 aacaagctgg agtgtataac cttgaggagt tagatccaga tccattcatg gaagctttga
     2341 atgagtatgg tttgccatgg gttgtggttg aaaatccaca aatggtggac taatgaagtt
     2401 agaacaagta ccaacaccag cctatgttat tgacttggcc aagttagaag ctaattgccg
     2461 cattctacaa tatgtacaag aagaggccgg ttgcaaggtc ttgcttgccc agaaggcata
     2521 ttccctctac aaaacttatc ccttgattag ccagtatcta tcaggtacga cagctagtgg
     2581 actctatgag gccaaattgg caagggaaga atttcctggt gaagtccatg tttttgcacc
     2641 agctttcaag gatgaggaca tggaggaatt gcttgggata acagaccata tcgtctttaa
     2701 ctcagagaga cagttgcgta agcatggggc tcgttgtcga gaggctggtg tcagtgttgg
     2761 tttgcgcctc aaccctcagt gttcaactca aggagatcac gcgctctatg acccttgtgc
     2821 acctggttct cgctttggag ttactataga caagattccg agtgatttgc tagatttggt
     2881 tgacggactt cattttcata ccctttgcga gcagggagca gatgatttac aaacaacttt
     2941 gaaagcagta gaagaacagt ttggtcccta cttacatgag gtaaaatggc tcaatatggg
     3001 tggtggtcat catattacaa gagaaggtta cgatgtggat ttgctgattt cagaaatcaa
     3061 gcgtatccga aaaacttaca atcttgaaat ctatatcgag cctggtgaag ccattgcgct
     3121 taatgcgggt tatttagcaa ctgaggtatt agatattgta gaaaacggta tggaaatctt
     3181 ggttttagac gcctctgcga cctgccatat gcctgatgta cttgagatgc cctatcgtcc
     3241 acctttgaga aatggctttg agtcacagga aaaagcccat acctacagac tttcttctaa
     3301 tacctgtctg actggcgatg tgattggtga ttatagtttt gaaaatccag tccaaatcgg
     3361 agacagactt tattttcaag acatggccat ttattctttt gtcaaaaata atacctttaa
     3421 tggtattgga ttgccaagtc tctatctcat ggacgaacag ggagactgta gcttactcaa
     3481 agcttttggc tatcaagact ttaaagggag attatcatga tggacagtcc aaaaaaatta
     3541 ggctatcaca tgccagcaga gtacgaaccc catcatggta ccctcatgat atggccgact
     3601 cgaccaggat catggccttt tcaaggaaag gctgctaaaa gagcatttac tcagatcatc
     3661 gagaccatag cagaagggga aagagtctat cttttggtgg agcaggccta tctatctgaa
     3721 gcccaatcct atcttggaga caaggttgtt tatttagaca ttcccaccaa tgatgcctgg
     3781 gcgcgtgata ctggcccaac cattctcgtc aatgataaag gtaagaaatt agccgtggat
     3841 tgggccttta atgcttgggg aggcacctat gatggtcttt atcaagatta tgaagaggat
     3901 gaccaagtag ccagtcgttt tgctgaggcc ttggaaaggc ctgtctatga tgctaaacct
     3961 tttgtactgg aaggaggcgc aatccatagc gatggtcaag gaactattct cgtaactgaa
     4021 agttgcttgc ttagtcctgg tcgcaatcct aacctgacta aagaggagat tgaaaacaca
     4081 ttattagaaa gtcttggtgc tgaaaaagtt atttggcttc cttatggtat ttatcaggat
     4141 gaaaccaatg aacacgtcga taatgttgtt gcctttgttg gtcctgctga ggttgttttg
     4201 gcttggacag atgacgaaaa tgatccccag tatgccatgt caaaagcaga tctcgaactc
     4261 ttagaacagg aaacagatgc aaaaggttgt cacttcacca ttcataaatt gcctatccct
     4321 gcagttcgac aagttgtgac agaagaagat ttgccaggct acatctatga agaaggagaa
     4381 gaagagcgat acgcaggtga acgactagca gcttcctacg taaactttta tatcgccaac
     4441 aaggctgtct tggttccaca gtttgaggat gtaaacgacc aagtggcctt agatatcctc
     4501 agcaagtgtt tcccagaccg taaagttgtc ggaataccag ccagagatat tctcttaggt
     4561 ggtggcaata tccactgtat cacccaacaa attccagaat aggagaaaaa gatgagaaat
     4621 gtaagagttg caaccattca gatgcaatgc gctaaggatg tggcaacaaa tatccaaacc
     4681 gcagagcgtt tagtacgtca ggctgctgag caaggagccc aaattattct cttgcccgag
     4741 ttgtttgaac atccctattt ctgtcaggaa cgtcagtatg actactacca gtatgcccaa
     4801 tctgtagcgg aaaatactgc cattcagcat tttaaggtga ttgccaagga actacaagtt
     4861 gttttaccaa tcagtttcta tgaaaaagat ggtaatgtct tgtataactc tattgccgtc
     4921 attgatgcag atgggggagt gctgggcgtt tatcgaaaga cccatatacc agatgaccat
     4981 tattatcaag aaaaattcta tttcacgcct ggtaacactg gtttcaaggt ctggaatact
     5041 cgctatgcta agattggtat cggtatctgt tgggatcaat ggttccctga aacagcccgc
     5101 tgtcttgcat tgaatggtgc tgaattgctc ttttatccta cagctatcgg ttcagagcca
     5161 attttggata cagatagttg tggtcactgg caacgtacta tgcaagggca cgcagcagcg
     5221 aatattgttc cagtcatcgc agccaatcgt tatggtttag aggaggttac tcctagtgag
     5281 gaaaatggcg gacagagttc cagtcttgac ttctacggtt cctcctttat gacggatgaa
     5341 acaggagcta ttctagaacg agctgaaaga caagaagaag ctgttctgtt agctacttat
     5401 gacctagaca agggagcaag tgaacgtcta aactggggct tgtttcgaga tagaagacca
     5461 gaaatgtata gacaaattac agattagtgt gggagaaatg agagattcat tctgctagac
     5521 taacttctta ttagcaacta taagatacta tggcatctag taaatcgatt tttatgattc
     5581 gctattcttg tctattgatt agtccgtatt ttaaaatatt agcaaaaaag caaatagcag
     5641 taacttctgt ctatttgctt ttctttttta tagaatatat ttctcaatag cacgcgcaac
     5701 gccgtcttct tcgttgcttg aggtaacggc atccgcaaga gatttgacat aatcgctggc
     5761 atttcccatt gcaatcccaa gccctgcaaa ctggagcatt tcgatatcgt tattagcatc
     5821 gcccatggcc ataatctctg aggaatcaat cttcaaaatc tcagctagtc gtgaaagagc
     5881 agtagccttt gtcgttccaa gcggcattgc ttcataaatg acaggctgcg aacgaactcc
     5941 actgaatcgt tggcaaagct cttcagcaaa acgctgctca aaatcgtctg tttgttcttt
     6001 tgttcctaaa aacatacctt ggaacatccg gaactttcca ctagtcgctt cttcaagaga
     6061 aatttcagtc aggtctgaaa atactagttt agcatcattt tcaataactt gattgggttt
     6121 gccaccgaga acaaaataat gtgactcgtc aaaaagtgtc aactgaacat cactcttttc
     6181 agcaaggtca tagaggtatt cgatgtcagc tggactcagt tctttccagt caactagact
     6241 ccaatcactg gtctggtgag ttgaacaacc gttgttaaca ataatatatt cgttctggag
     6301 gtcaagctcc agttttttgt agtaggggag gacaccgaaa agggggcgac ccgtacagag
     6361 aaccagtttg acaccttttt caatggcttt gtgaatagca gtaatgtgag cttgtgggat
     6421 ttccttggct tcattgagga gggtgccgtc catatccaag gctagtagtt taatcatagg
     6481 tcttccttct ttatcttttg ctattattat agcatatttt ggagaagaaa ttgatagaaa
     6541 gcttgagact aattgatttt atagtttaag atgttttgat gacaattcat gatttgaaga
     6601 ggatatttgg caaagatatg ctatactatg tttgtcaatg ttgcaactag acaaattaaa
     6661 aaaccaactt aatataatag tttttttgta agtaggtatg agtatcagat tactcaacta
     6721 atctgaagaa taatggagga aatatatcat gattttaatg acaaaaaata taaatctaac
     6781 aaatgaagaa ttagagctga tacaaggtgg agcagattca tatggtaaaa atcctaatgg
     6841 taggtacgat tgggaaatag aaccagtatt aactctgccg gttcatggat tttgttccag
     6901 aggcacctat gatttaggat atattggagg aggcaatcat ctttgcaaag gaagtgctgc
     6961 gagattttaa gtaaaattta ttagtaatat gaagaaacaa gtggagaaag cagagaattt
     7021 aatatgaaaa aacgggctat tcaaatttta ctagcattgt ccttaatttt ttacaaatca
     7081 acttggtttt ggagagtttt caatcacctc gcaaagccct atctaccagc aagtcgtgaa
     7141 ttttttcaga ttctgctttt gatggagagc ggagttcttt tcttagcggt catctatcta
     7201 ctggtttttg caggaaagaa aatttttcat ttcaagtggc agctgaggta cttcatctac
     7261 cttttactgg gctacatcat ttcatatatg tctgacttcc tcttttcgta tttcatatcc
     7321 ctgtcttcaa atcagatttc tttgaatgaa acgatagaaa tgatggggag acaggagttc
     7381 ccttatttct tgctcatcgt ttgcttcatc gcccctattg ctgaggaatt gatttatcga
     7441 ggtgtgctta tgacaacctt tttcaaaaac tcaccttggt acggagatgt tttgctttct
     7501 gctattattt tcggttatat tcatatcaat tttgctttaa ctcctcttgc ttttttcatt
     7561 tatgctagtg gaggtctgat tttagctcta ttgtatcgca tgactaaaaa tctctactat
     7621 ccaatactag ttcatattct catcaatatc actgccttct gggatgtttg gttactccta
     7681 ttttcaggaa gttagcttac taaaaaaatg tcggaatttt ccggcatttt cttttttcac
     7741 aaatagtcaa cgtttttctt tccgatactg aagtggtgtg tagccactta tttttttgaa
     7801 ttgattttga aaataagatt ggcgtgagaa aggcagatag tgaagatagt taagaagaat
     7861 aggatgttct tttttccttt ttggaaaact tctaaaatat ggtataatga aaagataaag
     7921 aagttggggg tagaagatga acattcaaca attacgctat gttgtggcta ttgccaatag
     7981 tggtactttt cgtgaagctg ctgaaaagat gtatgttagt cagccgagtc tgtctatttc
     8041 tgttcgtgat ttggaaaaag agttgggctt taagattttc cgtcggacca gctcagggac
     8101 tttcttgacc cgtcgtggga tggaatttta tgaaaaagcg caagaattgg ttaaaggatt
     8161 tgatattttt caaaatcagt atgccaatcc tgaagaagaa aaagatgaat tttccgttgc
     8221 tagccagcac tatgacttct taccaccaac tattacggcc ttttcagagc gctatcctga
     8281 ctataagaac ttccgtattt ttgaatcaac tactgttcaa atattagatg aagtggcgca
     8341 agggcatagt gagattggga ttatctacct caacaatcaa aataaaaagg ggattatgca
     8401 acgggttgaa aagttaggtc tggaggtcat cgaattgatt cctttccata cccatattta
     8461 tctctgtgag ggtcatcctt tagcccagaa agaggaatta gtcatggagg atttagcgga
     8521 tttaccaacg gttcgtttca ctcaagagaa agacgagtac ctttattatt cagagaactt
     8581 tgtcgatacc agcgctagct cacagatgtt taatgtgaca gaccgtgcca ccttgaatgg
     8641 tattttggag cggacggacg cctatgcgac aggttctgga tttttagata gtgacagtgt
     8701 taatggcatt acagttattc gtctcaagga taacctagat aaccgcatgg tctatgttaa
     8761 acgtgaagaa gtggagctta gtcaagctgg gactctcttc gtagaagtca tgcaagaata
     8821 ttttgatcaa aagaggaaat catgaaaaaa agagcaatag tggcagtcat tgtactgctt
     8881 ttaattgggc tggatcagtt ggtcaaatct tatatcgtcc agcagattcc actgggtgaa
     8941 gtgcgctcct ggatccccaa tttcgttagc ttgacctacc tgcaaaatcg aggtgcagcc
     9001 ttttctatct tacaagatca gcagttgtta ttcgctgtca ttactctggt tgtcgtgata
     9061 ggtgccattt ggtatttaca taaacacatg gaggactcat tctggatggt cttgggtttg
     9121 actctaataa tcgcgggtgg tcttggaaac tttattgaca gggtcagtca gggctttgtt
     9181 gtggatatgt tccaccttga ctttatcaac tttgcaattt tcaatgtggc agatagctat
     9241 ctgacggttg gagtgattat tttattgatt gcaatgctaa aagaggaaat aaatggaaat
     9301 taaaattgaa actggtggtc tgcgtttgga taaggctttg tcagatttgt cagaattatc
     9361 acgtagtctc gcgaatgaac aaattaaatc aggccaggtc ttggtcaatg gtcaagtcaa
     9421 gaaagctaaa tacacagtcc aagagggtga tgtcgtcact taccatgtgc cagaaccaga
     9481 ggtattagag tatgtggctg aggatcttcc gctagaaata gtctaccaag atgaggatgt
     9541 ggctgtcgtt aacaaacctc agggaatggt tgtgcacccg agtgctggtc ataccagtgg
     9601 aaccctagta aatgccctca tgtatcatat taaggacttg tcgggtatca atggggttct
     9661 gcgtccaggg attgttcacc gtattgataa ggatacgtca ggtcttctca tgattgctaa
     9721 aaacgatgat gcgcatctag tacttgccca agaactcaaa gataaaaagt ctctccgcaa
     9781 atattgggcg attgttcatg gaaatctgcc taatgatcgt ggtgtaattg aagcgccgat
     9841 tggccggagt gaaaaagacc gtaagaaaca ggctgtaact gctaaaggga agcctgcagt
     9901 gacgcgtttt cacgtcttgg aacgctttgg cgattatagc ttagtagagt tgcaactgga
     9961 gacagggcgc actcatcaaa tccgtgtcca catggcttat atcggccatt cagtcgctgg
    10021 tgatgaggtc tatggtcctc gcaagacttt gaaaggacat ggacaatttc ttcatgccaa
    10081 gactttaggt tttactcatc cgagaacagg taagaccttg gaatttaaag cagatatccc
    10141 agagattttt aaggaaacct tggagagatt gagaaagtaa gaatgaaaaa gaaattaact
    10201 agtttagcac ttgtaggcgc ttttttaggt ttgtcatggt atgggaatgt tcaggctcaa
    10261 gaaagttcag gaaataaaat ccactttatc aatgttcaag aaggtggcag tgatgcgatt
    10321 attcttgaaa gcaatggaca ttttgccatg gtggatacag gagaagatta tgatttccca
    10381 gatggaagtg attctcgcta tccatggaga gaaggaattg aaacgtctta taagcatgtt
    10441 ctaacagacc gtgtctttcg tcgtttgaag gaattgggtg tccaaaaact tgattttatt
    10501 ttggtgaccc atacccacag tgatcatatt ggaaatgttg atgaattact gtctacctat
    10561 ccagttgacc gagtctatct taagaaatat agtgatagtc gtattactaa ttctgaacgt
    10621 ctatgggata atctgtatgg ctatgataag gttttacaga ctgctgcaga aaaaggtgtt
    10681 tcagttattc aaaatatcac acaaggggat gctcattttc agtttgggga catggatatt
    10741 cagctctata attatgaaaa tgaaactgat tcatcgggtg aattaaagaa aatttgggat
    10801 gacaattcca attccttgat tagcgtggtg aaagtcaatg gcaagaaaat ttaccttggg
    10861 ggcgatttag ataatgttca tggagcagaa gacaagtatg gtcctctcat tggaaaagtt
    10921 gatttgatga agtttaatca tcaccatgat accaacaaat caaataccaa ggatttcatt
    10981 aaaaatttga gtccgagttt gattgttcaa acttcggata gtctaccttg gaaaaatggt
    11041 gttgatagtg agtatgttaa ttggctcaaa gaacgaggaa ttgagagaat caatgcagcc
    11101 agcaaagact atgatgcaac agtttttgat attcgacaag acggtttagt aaacatttca
    11161 acttcctaca agccgattcc aagttttcaa gctggttggc ataagagttc atatggaaac
    11221 tggtggtatc aagcgcctga ttctacagga gaatatgctg tcggttggaa tgaaattaag
    11281 ggtgaatggt attactttaa ccaaacgggt atcttattac agaatcaatg gaaaaaatgg
    11341 aacaatcgtt ggttctattt gacagactct ggtgttgctg ctaaaaattg gaagaaaatc
    11401 gctggaatct ggtattattt taacaaagaa aaccagatgg aaattggttg gattcaagat
    11461 aaagagcagt ggtattattt ggatgttgat ggctctatga agacaggttg gcttcaatat
    11521 aaggggcaat ggtattactt tgctccatca ggggaaatga aaacgggctg ggtaaaagat
    11581 aaagaagcct ggtactatat ggattctact ggtatcatga agacaggtga gatagaagtt
    11641 gctagacatc attactatct agaagaatca ggagctatga agcaaggctg gcttaaaaag
    11701 gcaaatgatt ggtatttcta caagacagat ggttcacgag ctataggttg gattaaagac
    11761 aaggataaat ggtacttctt gaaagaaaat ggtcaattac ttgtgaatgg taagacacca
    11821 gaaggctata ctgtggattc aagtggtgcc tggttagtgg atgttccgat cgagaaatct
    11881 gctacaatta aaactacaag tcattcagaa ataaaagaat ccaaagaagt agtgaaaaag
    11941 gatcttgaaa ataaagaaac gagtcaacat gaaagtgtta caaattcttc aactagtcaa
    12001 gatttgacat cctcaacttc acaaagctct gaaacgagtg taaacaaatc ggaatcagaa
    12061 cagtagtaga aaagaaggtt ttagggcctt ctttttccta tcaactcttt tctatttcct
    12121 gttattcatg ttataatgga taaatatgaa taatcggagt gagactatga aatacaaacg
    12181 gattgtcttt aaggtgggta cttcttctct gacaaatgag gatggaagtt tatcacgtag
    12241 taaggtaaag gatattaccc agcagttggc tatgctgcac gaggctggtc atgagttgat
    12301 tttggtgtct tcaggtgcca ttgcggctgg ttttggagcc ttaggattta aaaagcgtcc
    12361 gactaaaatt gctgataaac aggcttcagc agcggtaggg cagggacttt tgttggaaga
    12421 atatacgacc aatcttctct tgcgtcaaat cgtttctgca caaatcttgc tgacccaaga
    12481 tgactttgtg gataagcgtc gttataaaaa tgcccatcag gctttgtcgg ttttgctcaa
    12541 ccgtggggca attcctatca tcaatgagaa tgatagtgtc gttattgatg agctcaaggt
    12601 tggggacaat gacactctaa gtgctcaagt agcggcgatg gtccaagcag accttttagt
    12661 tttcttgaca gatgtggacg gtctctatac tggaaatcct aattcagatc caagagccaa
    12721 acgcttggag agaatcgaga ccatcaatcg tgagattatt gatatggctg gtggagctgg
    12781 ttcgtcaaac ggaactgggg gtatgttaac caaaatcaag gctgcaacta tcgcgacgga
    12841 atcaggagtt cctgtttata tctgctcatc cttgaaatca gattccatga ttgaggcggc
    12901 agaggagacc gaggatggtt cttactttgt tgctcaagag aaggggcttc gtacccagaa
    12961 acaatggctt gccttctatg ctcagagtca aggttctatt tgggttgata aaggggctgc
    13021 ggaagctctc tctcaacatg gaaagagtct tctcttatct ggtatcgttg aagcagaagg
    13081 agtcttttct tacggtgata tcgtgacagt atttgataag gaaagtggaa aatcacttgg
    13141 aaaaggacgc gtgcaatttg gagcatctgc tttggaggat atgttgcgtt ctcaaaaagc
    13201 caagggtgtc ttgatttacc gtgacgactg gatttccatt actcctgaaa tccaactact
    13261 ttttacagaa ttttagaggt aaactatggt gagtagacaa gaacaatttg aacaggtaca
    13321 ggctgttaaa aaatcgatta acacagctag tgaagaagtg aaaaaccaag ccttgctagc
    13381 catggctgat cacttagtgg ctgctactga ggaaatttta gcggctaatg ccctcgatat
    13441 ggcagcggct aaggggaaaa tctcagatgt gatgttggat cgtctttatt tggatgcaga
    13501 tcgtatagaa gcgatggcaa gaggaattcg tgaagtggtt gccttaccag atccaatcgg
    13561 tgaagtttta gaaacaagtc agcttgaaaa tggtttggtt atcacaaaaa aacgtgtagc
    13621 tatgggtgtc atcggtatta tctatgaaag ccgtccaaat gtgacgtctg atgcggctgc
    13681 tttgactctt aagagtggaa atgcggttgt tcttcgtagt ggtaaggatg cctatcaaac
    13741 aacccatgcc attgtcacag ccttgaagaa gggcttggag acgactacta ttcatccaaa
    13801 tgtgattcaa ctggtggagg atactagccg tgaaagtagt tatgctatga tgaaggccaa
    13861 gggctatcta gaccttctca ttcctcgtgg aggagctggc ttgatcaatg cagtggttga
    13921 gaatgcgatt gtacctgtta tcgagacagg gactgggatt gtccatgtct atgtggataa
    13981 ggatgcagac gaagacaagg cgctgtctat catcaacaat gctaaaacca gtcgtccttc
    14041 tgtttgtaat gccatggagg ttctgctggt tcatgaaaac aaggcagcaa gcatccttcc
    14101 tcgcttggat caaatgctgg ttgcagatcg aaaagaagct gggttggaac caattcaatt
    14161 ccgcctagat agcaaagcaa gccagtttgt ttcaggtcaa gctgctcaag cacaagactt
    14221 tgataccgag tttttagact atattctagc tgttaaggtt gtgagcagtt tagaagaagc
    14281 ggttgcgcat attgaatccc acagtaccca tcattcggat gctattgtga cggaaaatgc
    14341 tgaagctgca gcatacttta cagatcaagt ggactctgca gcggtgtatg ttaatgcctc
    14401 aactcgtttc acagatggag gacaatttgg tcttggttgt gaaatgggga tttctactca
    14461 gaaattgcac gcgcgtggtc caatgggctt gaaagagttg accagctaca agtatgtggt
    14521 tgctggtgat gggcagataa gggagtaaga gatgaagatt ggatttatcg gtttggggaa
    14581 tatgggtgct agcttggcaa aatctgtctt gcagactagg acgtcagatg agattctcct
    14641 tgccaatcgt agtcaagcta aggtagatgc tttcattgca gactttggtg gtcaggcttc
    14701 cagcaatgaa gaaatgtttg cagaagcaga tgtgattttt ctaggagtta agcctgctca
    14761 gttttctgaa ctgctttctc aatatcagac catccttgaa aaaagagaaa gtcttctttt
    14821 gatttcgatg gcagctggat tgaccttaga aaaactagca agtcttatcc caagccaaca
    14881 ccgaattatt cgtatgatgc ctaatacccc tgcttctatc gggcaaggag tgattagtta
    14941 tgccttgtct cctaattgca gggctgagga cagtgagatc ttttgtcagc ttttagccaa
    15001 ggctggtctc ttggttgaat taggagaaag cttaatcaat gcagcgacag gtcttgcagg
    15061 ttgtggacca gcctttgtct atctctttat tgaggccttg gcagatgcag gtgttcagac
    15121 gggattacca cgagaaacag ccttgaaaat ggcagcccaa actgtggtag gagctgggca
    15181 attggtccta gaaagccagc aacatcctgg agttttgaaa gatcaagttt gtagtccagg
    15241 cggttcgact attgctggcg tagcaagctt agaagcgcat gcttttcgag gcatagtcat
    15301 ggaggcagtt catcaagcct ataaacgaac acaagaacta ggtaaataag aggtagcttt
    15361 gactgcctct tttatggtgg ctgaaatgag aagacacaaa aagattgtca caaactccta
    15421 tttttttgat agaatagaag tagtaaaaaa gaaatgagtt agacatgtca aaaggatttt
    15481 tagtctctct tgagggacca gagggagcag gcaagaccag tgttttagag gctctgctac
    15541 caattttaga ggaaaaagga gtagaggtgc tgacgacccg tgaacctggc ggagtcttga
    15601 ttggggagaa gattcgggaa gtgattttgg atccaagtca tactcagatg gatgctaaaa
    15661 cagagctact tctctatatt gccagtcgca gacagcattt ggtggaaaaa gttcttccag
    15721 cccttgaagc tggcaagttg gtcatcatgg atcgttttat cgatagttct gttgcctatc
    15781 agggatttgg tcgtggctta gatattgaag ccattgactg gctcaatcag tttgcgacag
    15841 atggcctcaa acccgatttg acactctatt ttgacatcga ggtggaagaa gggctggctc
    15901 gtattgctgc taatagtgac cgcgaggtta atcgtttgga tttggaaggg ttggacttgc
    15961 ataaaaaagt tcgtcaaggc tacctttctc ttctggataa agagggaaat cgcattgtca
    16021 agattgatgc tagtctccct ttggagcaag ttgtggaaac taccaatgct gtcttgtttg
    16081 acggaatggg cttggccaaa tgaaacaaga tcaactaaag gcttggcaac cagctcagtt
    16141 tgaccgtttt gtccgtatct tagaacaaga ccagctcaat cacgcctatc tcttttcagg
    16201 tttctttgga agcttggaaa tggcgcaatt tttagctaag agcctttttt gtacggataa
    16261 agttggcgtc ttaccatgtg agaaatgccg aagttgcaag ctgattgaac aggaagagtt
    16321 tccagatgtc accttgatta agccagtcaa tcaggtcatc aagacagaac gtattcggga
    16381 attggtggga cagttttctc aagcagggat tgaaagccag caacaggtct ttatcatcga
    16441 gcaagcggat aaaatgcatc ccaacgcagc caattctctg ctcaaggtca tcgaagaacc
    16501 ccagagtgaa gtttatattt tcttcttgac tagcgatgag gaaaagatgt taccgacaat
    16561 ccgaagtcgg actcagatct tccactttaa aaagcaagaa gaaaaactta tcttactctt
    16621 agaacaaatg ggacttgtta agaaaaaagc gactctttta gctaagttta gtcaatcgcg
    16681 agctgaagca gaaaagttgg cacatcaggc aagtttttgg accttggtcg atgaaagtga
    16741 acgcctgctg acttggttag tagctaagaa aaaagaaagt tatctacagg ttgccaaatt
    16801 agccaacttg gcagatgata aggaaaaaca ggatcaggtt ttacggattc ttgaagttct
    16861 ctgtgggcag gacctcttgc aggtaagagt aagagtgatt ctacaagatt tactagaagc
    16921 tagaaaaatg tggcaagcta atgtcagctt tcaaaatgcc atggaatatc tggtcttgaa
    16981 agaaatataa actcaaaaat gaatgataaa gaaaggaaag ggctgtttta tggacaaaaa
    17041 agaattattt gacgcgctgg atgatttttc ccaacagtta ttggtaacct tggccgatgt
    17101 ggaagccatc aagaaaaatc tcaagagcct ggtagaggaa aatacagctc ttcgtttgga
    17161 aaattctaag ttgcgagaac gcttgggtga ggtggaagca gatgctcctg tcaaggccaa
    17221 gcatgttcgt gaaagtgtcc gtcgcattta ccgtgatgga tttcacgtat gtaatgattt
    17281 ttatggacaa cgtcgagagc aggacgagga atgtatgttt tgtgacgagt tgctatacag
    17341 ggagtaggca tgcagattca aaaaagtttt aaggggcagt ctccctatgg caagctgtat
    17401 ctagtggcaa cgccgattgg caatctagat gatatgacct ttcgagctat ccagaccttg
    17461 aaagaagtag attggattgc tgctgaggat acgcgcaata caggtctttt gctcaagcat
    17521 tttgacattt ccaccaagca gatcagtttt catgagcaca atgccaagga aaaaattcct
    17581 gatttgattg gtttcttgaa agcagggcaa agtattgctc aggtctctga tgccggtttg
    17641 cctagcattt cagaccctgg tcatgattta gttaaggcag ctattgagga agaaattgca
    17701 gttgtgacag ttccaggtgc ctctgcagga atttctgcct tgattgccag tggtttagcg
    17761 ccacagccac atatctttta cggtttttta ccgagaaaat caggtcagca gaagcaattt
    17821 tttggcttga aaaaagatta tcctgaaaca cagatttttt atgaatcacc tcatcgtgta
    17881 gcagacacgt tggaaaatat gttagaagtc tacggtgacc gctccgttgt cttggtcagg
    17941 gaattgacca aaatctatga agaataccaa cgaggtacta tctctgagtt attagaaagc
    18001 attgctgaaa cgccactcaa gggcgaatgt cttctcattg ttgagggtgc cagtcagggt
    18061 gtggaggaaa aggacgagga agacttgttc gtagaaattc aaacccgcat ccagcaaggt
    18121 atgaagaaaa atcaagctat taaggaagta gctaagattt accagtggaa taagagtcaa
    18181 ctctacgctg cctaccacga ctgggaagaa aaacaataaa gggagatagg atgtaataat
    18241 tctgtctgtt tctgtttaac ttaattagtg atgataatat aaagatgtat cacttggtat
    18301 agaagctttg gtattaagtt ttttattaag cccatacgga ataccgatgg ttggagcagc
    18361 agttatagcg ttcttagaag gtataaatag aaaaataagg tcattttaaa tcaaaggatt
    18421 gataaatcag aaagaaggtg attttttgcg aacatacgaa aataaagaag aactaaaagc
    18481 tgagatagag aaaacatttg agaaatatat tttagaattt gataatattc cagaaaattt
    18541 aaaagataag agagctgatg aagttgacag aactccagca gaaaaccttg cttatcaggt
    18601 tggttggacc aacttggttc ttaaatggga agaagatgaa agaaaggggc ttcaagtaaa
    18661 aacaccatcg gataaattta aatggaatca acttggtgaa ttatatcagt ggttcacaga
    18721 tacctacgct catttatctc tgcaagagtt gaaagcaaaa ttaaatgaaa atattaattc
    18781 tatctctgca atgattgatt cgttgagtga ggaagaatta tttgaaccgc atatgagaaa
    18841 gtgggctgat gaagcgacta aaacagcgac ttgggaagtg tataagttta ttcatgtaaa
    18901 tacggttgca ccttttggaa ctttcagaac taaaatcaga aaatggaaga agatagtatt
    18961 ataaattata tttttaactt taaaaaattt cataaaaatg gttaccaaag gcgatagaag
    19021 aaaaactatc gtctttttct ttgcaaattt ttaagaaggg aggtgatctt gcatggactt
    19081 tgaatatttt tataacagag aagcggaaag atttaacttc ttaaaagtac cggagatatt
    19141 agttgataga gaagaatttc ggggcttatc agcagaagca attatccttt attccatact
    19201 tcttaaacgg acaggaatgt catttaagaa taactggata gacaaggaag gcagagtatt
    19261 tatctatttt actgtcgaag aaattatgaa aagaagaaat atctcaaagc caactgccat
    19321 aaaaacatta gatgagcttg atgtaaaaaa aaggaatagg actgatcgaa agagtaaggc
    19381 ttggacttgg taagccgaac atcatttatg ttaaagactt tatgagtata tttcaggtaa
    19441 aagaaaatga cttacaaaag tcaaaaaact taacttcaga agtaaaagat tttaacctca
    19501 gaagtaaaga aaatgaactt caagaggtta agaaccttga ctctaactat atagagaata
    19561 ataagagtaa gtatagtaag agagaatata gttttggtga aaacggactt ggaacatttc
    19621 aaaatgtgtt tttagctgtt gaagatatat cggatttaca aatcataatg aactcacagc
    19681 ttgagaatta ca
//
LOCUS       DBERCW010000034        19641 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.034, whole genome shotgun sequence.
ACCESSION   DBERCW010000034 DBERCW010000000
VERSION     DBERCW010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.034"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            168..857
                     /locus_tag="ACL72M_001598"
     CDS             168..857
                     /locus_tag="ACL72M_001598"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS0716703.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPK
                     EIAQRFINVIK"
     gene            882..1799
                     /locus_tag="ACL72M_001599"
     CDS             882..1799
                     /locus_tag="ACL72M_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HGS0716704.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            1827..3368
                     /locus_tag="ACL72M_001600"
     CDS             1827..3368
                     /locus_tag="ACL72M_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HGS0716705.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGVTGL
                     ILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIV
                     VSIIMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTENKVSAPKYTTIHDISEIKADSS
                     WEVRH"
     gene            3394..3852
                     /locus_tag="ACL72M_001601"
     CDS             3394..3852
                     /locus_tag="ACL72M_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS0716706.1"
                     /translation="MIISEQSDFRRYASVNKHFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            3854..6076
                     /locus_tag="ACL72M_001602"
     CDS             3854..6076
                     /locus_tag="ACL72M_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004308 - exo-alpha-sialidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sialidase domain-containing protein"
                     /protein_id="HGS0716707.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTQVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6116..7225
                     /locus_tag="ACL72M_001603"
     CDS             6116..7225
                     /locus_tag="ACL72M_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS0716708.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            7382..8272
                     /locus_tag="ACL72M_001604"
     CDS             7382..8272
                     /locus_tag="ACL72M_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS0716709.1"
                     /translation="MKIIGIDIGGTTIKADLYDDFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYVLNYSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTSEIEKRF
                     GLSTFVENDVNCAALGELWEGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLSSGDKVAKETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNVVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            8297..8620
                     /locus_tag="ACL72M_001605"
     CDS             8297..8620
                     /locus_tag="ACL72M_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716710.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELISIESNLEMKQQNLIDEVNKTIKENDAKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            8610..10601
                     /locus_tag="ACL72M_001606"
     CDS             8610..10601
                     /locus_tag="ACL72M_001606"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HGS0716711.1"
                     /translation="MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMNKQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKW
                     EKLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIKVMDERFGHSIYIYE
                     SETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ITTTSDVMTILVVSVVFGFITVFVGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            10617..11093
                     /locus_tag="ACL72M_001607"
     CDS             10617..11093
                     /locus_tag="ACL72M_001607"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HGS0716712.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11127..11708
                     /locus_tag="ACL72M_001608"
     CDS             11127..11708
                     /locus_tag="ACL72M_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716713.1"
                     /translation="MSNLENLRESVIEQAHEKGSMKLLDSKKKIDDEFEMQKSVIVKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            11773..12780
                     /locus_tag="ACL72M_001609"
     CDS             11773..12780
                     /locus_tag="ACL72M_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HGS0716714.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILEA
                     TPYHLSIDVLENPSQTEISLMTKLVNDYRWAYAESPSDKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELGEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKTLDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYG
                     S"
     gene            12770..13090
                     /locus_tag="ACL72M_001610"
     CDS             12770..13090
                     /locus_tag="ACL72M_001610"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HGS0716715.1"
                     /translation="MEANKYKIGIIGSHDIILPFSMIGFDIFSAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            13153..14928
                     /locus_tag="ACL72M_001611"
     CDS             13153..14928
                     /locus_tag="ACL72M_001611"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HGS0716716.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            14929..16314
                     /locus_tag="ACL72M_001612"
     CDS             14929..16314
                     /locus_tag="ACL72M_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HGS0716717.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            16337..16948
                     /locus_tag="ACL72M_001613"
     CDS             16337..16948
                     /locus_tag="ACL72M_001613"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HGS0716718.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            17221..17406
                     /locus_tag="ACL72M_001614"
     CDS             17221..17406
                     /locus_tag="ACL72M_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716719.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            17387..17710
                     /gene="tnpB"
                     /locus_tag="ACL72M_001615"
     CDS             17387..17710
                     /gene="tnpB"
                     /locus_tag="ACL72M_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0716720.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(17865..18173)
                     /locus_tag="ACL72M_001616"
                     /pseudo
     CDS             complement(17865..18173)
                     /locus_tag="ACL72M_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            18155..18592
                     /locus_tag="ACL72M_001617"
                     /pseudo
     CDS             18155..18592
                     /locus_tag="ACL72M_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            18699..19357
                     /locus_tag="ACL72M_001618"
                     /pseudo
     CDS             18699..19357
                     /locus_tag="ACL72M_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            19450..>19641
                     /locus_tag="ACL72M_001619"
     CDS             19450..>19641
                     /locus_tag="ACL72M_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS0716721.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVRE"
BASE COUNT         6502 a         2903 c         3955 g         6281 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccaaa agaaattgct cagcgattta
      841 ttaatgtcat caaataaaaa acaatataaa ggagaaatct gatgaaagat ttaactaaat
      901 acaaaggcgt tattcctgca ttttatgctt gctatgatga aaatggtgaa attagccaag
      961 aacgtgtaaa atctctggtg caatatttca ttgacaaagg tgtaaaaggt atctatgtaa
     1021 atggttcttc aggtgaatgt atttaccaaa gtgtagaaga tcgtaaacaa attattgaag
     1081 ctgttatgga agttgctaaa ggtaaattaa cagttatcaa ccatgttgca tgtaataaca
     1141 cgaaagatag tattgaattg gcaaaacatt cagaaagtgt tggagtcgat gctattgctg
     1201 ctatcccacc tatttacttc aaattgccag aatattcaat tgcagcatat tggaatgcaa
     1261 tgagtgaagc tgcgccaaat acagatttta tcatttataa tattccacaa ttggcagggg
     1321 ttgcgttgac tggtagtttg tatgcaacaa tgcgtcaaaa tcctcgtgtg attggagtta
     1381 aaaattcttc tatgcctgta caagatattc aaatgtttgt agctgcaggt ggagaagatt
     1441 acattgtatt caatggtcca gatgaacaat atcttggtgg tcgcttgatg ggagcagaag
     1501 ctggtattgg tggtacttat ggcgttatgc cagatttgtt cttgaaattg gaaagtttga
     1561 ttcaagaacg agatttagat actgctaaaa aacttcaata tgctatcaat gaagttatct
     1621 ataagatgat atcaggtaag gcaaatatgt atgctgtagc aaaagaggtt ttgcgtctaa
     1681 atgaaaaact tgatttaggt tctgttcgtc aacccttaga agcattggca gaaggtgact
     1741 tggaagttgc aaaacaagca gcagaactta ttcaacaagc acgaaaagaa tttttataat
     1801 aaataaaatc aatatggaga tatgttatgg gcacaacagg atttacaata attgacttaa
     1861 ttatcttgat tgtttattta cttgcggtgt tggttgcagg tatctatttc tctaaaaaag
     1921 agatgaaagg aaaagagttc tttaaaggag atggttcggt tccttggtat gttacttcgg
     1981 tatccatttt tgccacaatg ctcagtccga tttccttctt gggactcgct ggtaactctt
     2041 atgcaggtag ctggatttta tggtttgctc aattagggat ggttgtagct attccactga
     2101 caattcgttt tatcttacct atctttgcac ggatagacat cgatacggca tatgattact
     2161 tggataaacg ttttaattct aaagcacttc gtattatttc agcactcttg tttattattt
     2221 atcaattggg acgtatgtct atcattatgt acctcccatc agctggttta tcagtattga
     2281 caggaattga catcaatatt ttgattattt tgatgggtgc aattgcaatt gtttattctt
     2341 atactggtgg tctaaaatcc gtattatgga cagactttat tcaaggtgtg gttctgatta
     2401 gtggtgtcgt tgtagcttta tttgtactga tggctaatat taaaggtggc tttggtgcag
     2461 tagcagaaac attagcaaac gggaaattcc ttgctgcaaa tgaaaaactt ttcgatccta
     2521 acttgctttc aaactccatc ttcttaattg tgatgggttc aggctttaca atcttgtctt
     2581 cctatgcttc atctcaagat ttggttcaac gttttactac aacacaaaat attaagaaac
     2641 ttaataaaat gttgttcaca aatggtgtct tgtcacttgc aattgcaaca gtcttttact
     2701 tgatcggtac aggcttgtac gtattctatc aagtacaaaa tgcaggtagt gcagctagca
     2761 atatccctca agaccaaatc tttatgtact ttattgcata ccagttacca gtaggtgtca
     2821 caggtttgat cttggcagcg atttatgcag cagctcaatc aactgtttca acaggtttga
     2881 actctgttgc aacttcatgg acattggata ttcaagatgt catttctaaa aatatgtcag
     2941 aggatcgtcg tacgaaaatt gcacaattcg tatctctagc agtaggttta ttctcaattg
     3001 ttgtttccat tatcatggct cattcagata ttaaatctgc atacgaatgg ttcaatagtt
     3061 tcatgggact tgtacttggt ctacttggtg gtgtattcat tcttggtttt gtttctaaaa
     3121 aagcaaataa acaaggtgct tatgcagcgc tgattgtatc aaccatcgtt atggtattta
     3181 ttaaatactt ccttcctcca acagctgtta gctactgggc atattcattg atttcaattt
     3241 ctgtatcagt agtttcaggt tatattgtat ctgttcttac tgaaaataaa gtatctgcac
     3301 ctaaatatac aacgattcat gatatttcag aaattaaagc ggattcaagt tgggaagttc
     3361 gtcactagtc actaatagaa aagagaaaat aatatgatta tttctgaaca atctgatttt
     3421 agacgatatg cttctgtcaa taaacatttt tcaaaagtct gtgatttttt agaaaataca
     3481 aatttgacag atttagttga tggaaaaatt gatattgacg gggaaaatgt ttttgcaaat
     3541 tgtatgactt atctagctga tggagttcca ggagatattt ttgaaactca taagaaatat
     3601 ttagatattc atattgttgt tgaaaataca gaaaaaatgg cagtaacttc cccagttcgt
     3661 gctcagtcac gtgtaccttt tagcgaagag aaggatattg ctttttacga tagcaaagac
     3721 tatcaaattg ttgaattgct tccagggaat atgttggtga cttttgaaga agatcttcac
     3781 caaccaaaga ttcattgcaa tgatgaaact gttaaaaaac ttgttatcaa agttttaaac
     3841 gaggaaaaat aaaatgaaaa aaaatattaa acaatatgta accttaggta ctgtagtggt
     3901 attatcagca tttgttgcta actcagttgc agctcaggag actgaaactt ctgaagtatc
     3961 aacaccagag ttggtgcaac ctgttgcacc aacgacttcg atttcggaag tacaacataa
     4021 atcgggtaac tcttcggaag ttactgtaca acctcgaaca gttgaaacta ctgttaagga
     4081 tccatcttct acagcggaag aaactcctgt cttagaaaaa aataatgtta ctttaacagg
     4141 gggcggagaa aatgttacta atgagttaaa ggataaattt actagcggtg actttactgt
     4201 agtgattaag tacaatcagt ctagtgagaa aggtttacaa gctctgtttg gaatatctaa
     4261 ttctaaaccc ggtcaacaaa atagttatgt agatgtgttc cttagagaca atggtgaatt
     4321 gggaatggaa gcgcgtgata cttcttccaa taaaaatcac ctagtaacca gacctgcttc
     4381 agtttggggt aagtacaaac aagaggccgt gacgaacact gttgcagtag tagcagattc
     4441 agtcaaaaaa acgtattctt tatatgcaaa tggtacaaaa gtagtagaaa agaaagtgga
     4501 taacttccta aacatcaagg atattaaagg tattgattac tatatgcttg ggggagtgaa
     4561 acgtgcagga aaaacggcgt ttggttttaa cggaacacta gaaaatatca aattctttaa
     4621 tagtgcattg gatgaagaaa ctgttaaaaa gatgacaaca aacgctgtta ctggacattt
     4681 aatttatacg gctaatgata caacaggttc taactatttc cgtattccag ttctgtatac
     4741 ttttagcaat ggtcgggttt tttcaagcat tgacgctcgt tacggtggaa ctcatgattt
     4801 cttgaataaa attaatattg ctacaagtta tagtgatgat aatggtaaga catggactaa
     4861 accaaaatta acattagcat tcgatgattt tgcgccagca ccattagaat ggcctcgtga
     4921 tgttggtgga cgtgacttac aaatcagcgg tggtgcaacc tatattgact ctgttattgt
     4981 tgaaaaaaat aacaaacaag tactcatgtt tgctgatgtt atgcctgctg gagtaagttt
     5041 tagagaagct actagaaaag attcaggtta taaacaaatt gatggtaatt attaccttaa
     5101 attaaagaaa caaggtgata ctgattataa ttatactatt cgtgagcatg gtactgtata
     5161 cgacgatcgt accaacagac caactgaatt ttcagtagat aaaaatttcg gtattaaaca
     5221 aaatggtaat tatttgacgg tagagcaata ttcggtttca tttgaaaata ataaaaagac
     5281 tgaatatcgt aatgggactc aagtccatat gaatatcttc tacaaagatg cattattcaa
     5341 agtagtgcca acgaactata ttgcatatat ttctagcaat gatcatggcg aatcttggtc
     5401 tgcaccaact ttattacctc ctataatggg acttaatcgg aatgcgcctt atttgggtcc
     5461 tggacgtgga atcattgaaa gctcaactgg acgtattctt attccgtctt acactggtaa
     5521 agagtctgca ttcatttata gtgacgataa tggagcgtct tggaaagtta aagttgtgcc
     5581 acttccttct agttggtcag cagaagcaca atttgtagaa ttgagtccag gagtaattca
     5641 agcatacatg cgtacaaata atggtaaaat tgcatattta acaagtaaag atgcaggtac
     5701 tacttggagt gcgccggaat atttgaaatt tgtttcaaat ccaagttatg gaacacaatt
     5761 atcaatcatc aattatagtc aattgattga tggtaaaaag gctgtcattt taagtactcc
     5821 aaactccaca aatggtcgta aacacggaca aatttcgatt ggtctaatta atgatgataa
     5881 tacaattgat tggcgttatc atcacgatgt tgattatagt aactatggat actcatattc
     5941 aacattgaca gagttaccaa atcatgaaat tggattgatg tttgaaaaat ttgattcatg
     6001 gtctcgtaat gaacttcata tgaaaaatgt tgtaccatat ataacattta agattgaaga
     6061 tttgaaaaag aattaaagct gaaatttaaa aatatataga aagaggataa aaattatggt
     6121 aaattacggt attgttggag ctggatattt tggagctgat ttggctcgct caatgaacaa
     6181 aattgaagat gcaaaagtgg ttgcggtatt tgacccaaat catggagaag aagttgctca
     6241 agagttggga tcagatgttt gtgcaagttt agatgaactt gtagcacgtg aagatattga
     6301 ttgtgtgatc gtagcttcac ctagctacct tcaccgtgaa cctgttgtga aagctgctca
     6361 acatggcaaa cacgtatttt gtgaaaagcc aattgcattg tcttatgaag attgtaaagc
     6421 catggttgac gcatgtaaag aaaataatgt tatctttatg gctggtcaca tcatgaactt
     6481 ctttaatggt gtacaccatg ctaaagaatt gattactcaa ggtaaaatcg gtaaagttct
     6541 ttattgccat gccgctcgta caggttggga agaacaacaa ccaactgtat catggaagaa
     6601 acttcgttct caatctggag gacatttgta ccaccatatt catgaattag attgcattca
     6661 gttcatcatg ggaggacttc ctgaaaaagc gacaatggta ggaggcaatg tatatcataa
     6721 aggtgaaaac tttggtgatg aagatgatat gctcattgta aacctagaat actctgatga
     6781 tcgttatgct gttttggaat atggtaatgc tttccgttgg ggtgaacact acgtcttgat
     6841 tcaaggaact gaaggagcta tcaaacttga cttgttcaat actggaggta ctcttcgtgt
     6901 taaaggtgaa ggagaatcac acttcttagt acatgaaact caagaggaag atgatgaccg
     6961 tacagctatc tataccggtc gtggtatgga tggagcaatt gcgtacggta aaccaggagt
     7021 acgttgccca ttatggttac aaacatgtat tgataaagaa atggaatatc tacatgacat
     7081 cattaaaggt ggagaaatta cagaagaata tgaaaaactt ctcaatggtg tagctgcttt
     7141 agaatcaatc gctaccgctg atgcatgtac tttatcagtt aaagaagatc gaaaagtaag
     7201 tctttcagaa atcacaaatg cttaactatt gtaaaacaga atagtaaatt cttgtcatta
     7261 tataatttct aaagttctgt gatacaactc attgaataaa gaaatagaga tgggactggg
     7321 ataatgccca gtcccatttt ttatcaaaaa gtaatgagat caaaaatgtg ggagtgatga
     7381 aatgaagatt atagggatcg atattggcgg aacaacaatt aaggcagatt tatacgatga
     7441 ttttggaacg agtttaaatc agttcaaaga gatagaaaca attattgact atgatttggg
     7501 aacgaaccag atattaaatc aggtctgtga tttaattggt gagtatgttt taaattattc
     7561 aattgatggt gttgggattt ccactgctgg agttgttaat gctaatacag gagaaatcat
     7621 ctatgcaggc tatacaatac cagggtatat cggagtaaac tttacttccg aaatagaaaa
     7681 acgttttggg ttgtctactt ttgttgaaaa tgatgttaat tgtgctgcat taggtgaatt
     7741 gtgggaggga caagccaaag ataagaaaaa tgtagtaatg gttactattg gaacaggtat
     7801 aggaggcagt attattgtca atggacaaat tgttaacgga tttaactata ctgctggtga
     7861 agtaggctat attcctgtag gtaattcgga ttggcaaagc aaagcctcaa caaccgcatt
     7921 gattcattta tatcaaaaga agagcttgaa aactaatcaa actggacgta ctttctttac
     7981 tgatttaagt tctggagata aagtcgctaa agaaactttt gaaatttttg tagaaaatct
     8041 aacaaaaggt ttattaacta tttcttatct acttaatcca gaaattctca tattaggagg
     8101 tgggattctg gctaaaaagg atattttgtt acctgaaatt caaagttctt tagctaaaaa
     8161 tgcaatggat aataggtttt tgcctaaaaa tgttgtggca gctacattag gaaatgaagc
     8221 tggtcgtata ggagctgtaa aaaatttctt agatagaatt tctaataaat agtgtgaaag
     8281 ataaggaggt gtcacaatga ctaactctgt attttcgaca atgcaagata ttgagaatgt
     8341 tgcaaccgat attataaaat catatgataa tgagatttat acgtataaag ctgtctccca
     8401 agaagaattg gaaaaactag aaaaaagtta tgatgaaaaa agtcacgaag aattaatttc
     8461 aatagaaagc aatttagaaa tgaaacaaca gaacctcatt gatgaggtta ataaaacaat
     8521 caaggaaaat gatgcaaaga ttcagtatat ttcatcaagt aggagaggag aatttgtaga
     8581 aaaaattatt ggtagggtgg tagaaaaata tggctattag tcagatgaaa agaatttctc
     8641 tactatttac taagagtagt cttgatgatg ttttaaaaac tattcaagaa ctagagtcag
     8701 tgcagttccg tgatttaaag gttcaggata actggtcaga agcgctagaa aaagatgagg
     8761 ttgtattttc aactattcaa atttctcaca cttctaattc ccatcatggg gttattgaag
     8821 gaaatgatgc cttgaattat ttgatgaata aacaacaaca tttggaagca actgtagaga
     8881 aattacaaga atacctaccg aaagaaaaca cgtttaagtt attacagcaa cctccgataa
     8941 caacctctta tgaagaatta gaaaaatttg gtaaagctaa tgttgctgag ggtgttctta
     9001 aaaaagtgaa tcatcaaata aacagagttc atgaattaga aagaaacatt caaagtaata
     9061 atgaggaaat agagagatta ataaagtggg aaaaattaga aattattcct gcgcatttag
     9121 aacaattttc tttctgtaga ggaaaagtcg gaacaattcc aaggactgta gataatcgct
     9181 tatacaataa ttttttagaa aacaatattg aagttcaaga aatattttct aatgatagag
     9241 agtacggtgt tgttgttttc tatcagtcca gttgctctat tgattttgat gaatacttat
     9301 ttgaaccatt tgattattct agaaaggaat taccgaagca gcgagtagta gatttggatc
     9361 aagaaaacat gcagttaata actgaaaaag agaatattat cgcatcgttg caagattcaa
     9421 agaaaaattt gatagattta caatggcaaa ttgactatat tttatctatc tatgctcgtc
     9481 aaatctctaa gaataacctt ttgagcactc cgcatctagt tgcattagaa ggatggatag
     9541 aagaaactcg tattttatat tttataaaag ttatggatga gcgttttgga cattctattt
     9601 atatttatga atcggaaaca ttgtcggata atcaagatga aatacctatc aaattaacga
     9661 atcactcttt aattgaacca tttgaattat tgacagaaat gtatgctctg cccaaatatt
     9721 atgagaaaga tcctacacct gtattagcac cattttactt tacatttttt ggaatgatgg
     9781 ttgctgattt aggctatggt ttactattgt ttttaggaat aatgttagca ttaaaaattt
     9841 ttcatctacc ttcagtaact aagaaatttt taaaattctt taatatatta ggggtagccg
     9901 ttgcaatttg gggtggaatc tatggctcat tttttggata tgagttgcca tttcatctga
     9961 taactacaac ctcggatgtc atgactatat tagtagtgtc agttgtgttt ggatttatta
    10021 cagtatttgt aggtttgtta gcttcaggac tacaaaaagt aagaatgaag aaatatgcag
    10081 aagcatataa ttcaggattt gcgtggtgtg ttattctgct tggcttgtta tttattgctg
    10141 tcggaatgtt gatgcctgat attagaccgt tatttgtatt agggaaatgg gtatctattt
    10201 ttaatgctgt ggggattttg attgcttcta ttattcaagc caaaagcttg tcaggtattg
    10261 gctcaggatt gtttaatcta tataacattt catcttatat aggtgattta gttagtttca
    10321 ctcgattgat ggcattagga ttatctggag caagtatagc atcagctttc aatttaattg
    10381 ttggtttgtt tccggggaca ttggctaaac tgacaattgg attagtatta ttcattcttt
    10441 tacatgcgat caatattttt ctatcgttac tatcaggata tgttcatgga gcgcgtctga
    10501 tatttgttga attttttggt aagttttatg agggtggagg aaaaccattt caacctttga
    10561 aggcttctga gaaatatatt aaggttatta caaagaatta atggaggata tatataatgg
    10621 aacatttagc aacttatttt tcaacctatg gaggagcttt cttcgctgca ttgggaattg
    10681 tattggcggt tggattaagc ggtatggggt ctgcttatgg agttggtaag gctgggcaat
    10741 ctgccgcagc tttactgaaa gaacagccag aaaaatttgc ctcagctttg atattgcaac
    10801 tattgcccgg aacacaagga ttatatggtt ttgttattgg aattttgatt tggttgcaat
    10861 taactccaga acttcctttg gaaaaaggcg ttgcttattt ctttgtagct cttccaattg
    10921 ctattgtagg atacttttcg gctaagcatc aaggaaatgt agcagtagcg ggaatgcaaa
    10981 tcttggctaa aagaccaaaa gaattcatga agggagcaat tttggctgcc atggtagaaa
    11041 cctatgcaat tcttgccttt gtcgtatcat tcattttgac ccttcgtgta taagaaatta
    11101 atttgctatt caaaggaggt gtctaaatga gcaatttaga aaacttacga gaatctgtta
    11161 ttgaacaagc tcatgaaaaa gggagtatga aattattgga ttccaaaaag aagattgatg
    11221 atgaatttga aatgcaaaag tcggtcattg taaagaaaaa agaagctgaa catgaacgaa
    11281 agttaaaaga attacaacag aaatatcaaa taatttttca acaattaaaa aataaggaac
    11341 gccaatcaac gttagtatca aaacagaaaa tattaaaaga actttttcaa tctgctttaa
    11401 tagaaatgga atcttggagt gcagataaag aaatggagtt catctatcga attctggaac
    11461 gatattcaca acaagaggtc atagtaactt ttggggagcg gactttagct aaattcaatt
    11521 tggaacaatt agagaaattg aaattctctt ttccaaatca tttatttagt gaacagccta
    11581 tctcaaatga atcaggctta cttatttcaa taggtaaaat tgatgataac tatttgtata
    11641 aaacgttaat tggatcgatt tctaaggaag aaagttcaag tatcgcaaat caaattttta
    11701 tcaattaagg atgaaattgg ttaatccttc ttagaaattt ggagtattcc aataaaatta
    11761 gaaaggtatt ttatggatac taatcttttt tcaaaaataa atacgacgat ttcggtaaaa
    11821 gaaaacgatt ttattacaga agaaaaattt caaaaaatta tacaatccaa agatacggag
    11881 acattggcat ttatcttaga agcaactccc tatcatttat cgattgacgt tttagaaaat
    11941 cctagtcaga cagagatttc gctaatgaca aaattagtca atgattatag atgggcctat
    12001 gctgaaagtc cgtctgataa aattgtgact ttatttgctt tacgatatgt ttatcataat
    12061 atcaaagttt tattaaaatc taaggcggca attaagaaag atttttctaa attattaatt
    12121 ccaataggga tttttgatat agaaagttta aaacatttag tttcttcctt acattcagat
    12181 acacttcctg attttatggt tcatgaagta gaatcaattt ggaatgagta tgaaactttt
    12241 aataatattc gtgtacttga tgtcggagct gatctagcat attttaaaca tctgaaactt
    12301 ttatctaatg agttaggtga ggtgctgtct caggttattg ttgcaatgat tgacttttat
    12361 aatattatta ctgtaaaacg tggtttatct caaaataaga gtcatgggga tattttacaa
    12421 ttactttcag atgaaggaag tatttctgct aaagaattta tatacattgt agaaaatcaa
    12481 gaaatatttg tgtggttcaa taaaataaat ccaagcttag attcaatctt ttcaacttac
    12541 gaattgaaga tgcaggacgc aacaatttca tcttctgagt tagaattttt atgtgattta
    12601 ctattgtata aaactttaga tcaaggaagg tataatgtag atgggccgtt agttcttgct
    12661 agatatttat tgggatgtga gtttgaagta aagaatctta gaatgatcat atcagctctt
    12721 caaaatacaa ttccttttga atcaataaaa gaaaggatac gcccgcatta tggaagctaa
    12781 taagtataaa attggcataa ttggtagcca tgatattatt ttacccttta gcatgattgg
    12841 gtttgatata ttttctgcct atcaagaaca agaagctata aatactctaa gaaaattagc
    12901 tcaatctgat tatggtgtca tttatatcac tgaagacatt gcttcaatga tattagatac
    12961 aattcgccat tatgattctc aagttgtgcc tgctattatt ttattaccga ctcataaaca
    13021 aggtttaaat ttaggattaa aacgtataga ggataatgta gagaaagcag taggacacaa
    13081 tattttataa taatgtacaa aattgtctgt aatattattc tataattttt ggacttagta
    13141 aggagaataa ctttgactca agggaagatt ataaaagtat cgggacctct agttattgca
    13201 tcaggtatgc aggaggctaa tattcaagat atttgccgtg taggtaagct agggttaatc
    13261 ggtgaaatta ttgaaatgag aagagatcag gcatctatcc aagtctatga agaaacatct
    13321 ggtcttggtc cgggagaacc tgttgttaca actggagaac ctctctcggt tgaattaggg
    13381 ccaggattga tttctcaaat gtttgatggc atacaacgcc cattagatcg atttaaattg
    13441 gctactcata atgattttct agttcgtggg gtagaagttc caagtttgga tagagatatt
    13501 aagtggcatt ttgattccac tatagcaatt ggtcaaaaag tgagtacggg tgatattctt
    13561 ggaactgtca aggaaaccga ggtagttaat cataaaatta tggttcctta tggagtatct
    13621 ggagaagtcg tttctattgc atctggcgat tttacaattg atgaagttgt atatgaaata
    13681 aaaaaattgg acggtagttt ctataaagga acgcttatgc aaaaatggcc tgtccgcaag
    13741 gcgcgtcctg tttctaaacg tttaattcca gaagaaccat taatcacagg tcaacgagtt
    13801 attgatgcat tctttccagt aaccaaaggg ggagctgcag cagttcctgg accgtttgga
    13861 gcaggaaaga cagttgtaca acaccaagta gctaaatttg ccaatgttga tattgttatt
    13921 tatgtcggtt gtggagaacg tggaaatgaa atgacggatg tactgaatga gtttcctgag
    13981 ttgattgacc ctaataccgg acaatcaatt atgcaacgga cagttctgat tgctaatact
    14041 tcaaatatgc ctgttgctgc tcgtgaggct tcaatttata caggaattac catggctgag
    14101 tattttcgtg atatgggcta ctctgtcgcc attatggctg attcaacttc acgttgggca
    14161 gaagcgctac gtgaaatgtc aggacgtcta gaagaaatgc ctggtgatga gggttatcct
    14221 gcttatctgg gaagtcgtat cgctgaatat tatgaaagag caggacgttc tcaggttcta
    14281 gggcttccag aacgtgaagg aacgattact gctattggag ctgtatcgcc acctggtgga
    14341 gatatttcag aaccagttac tcaaaacact ttacggattg tgaaagtttt ttgggggctt
    14401 gatgctccgt tggcacagcg acgtcatttt cctgcaatta actggcttac atcttattca
    14461 ctatataaag acagtgtggg cacttatata gatggtaaag agaagacaga ttggaatagt
    14521 aaaataactc gtgcgatgaa ctacttacaa cgggaatcta gtttagagga aattgttcgt
    14581 cttgttggaa ttgattctct gtctgataat gaacgactaa cgatggaaat tgctaaacaa
    14641 attcgagaag attatttgca acagaacgct tttgattcgg tagatacatt cacttcgttt
    14701 gcaaaacaag aagcaatgct aagtaatatt ctcacttttg ctgatcaggc aaatcatgct
    14761 ttagagttgg gttcttactt tacagagatt atggaaggta ccgtggcagt tcgagaccgt
    14821 atggcgagaa gtaaatatgt ttcagaagat agattagatg aaatcaaaat tatatcaaat
    14881 gagattacac atcaaattca tttgatatta gaaacaggag gtctataaat gagtgttata
    14941 aaagaataca gaactgctag tgaagttgtt gggcctctta tgattgttga acaagtaaat
    15001 aatgtgtctt acaatgagtt agttgaaatt caacttcata atggagaaat tcgtcgtgga
    15061 caagttttag agatccacga agataaagca atggttcagc tttttgaagg atctagtgga
    15121 ataaatttag aaaagtctaa aattcgtttt gctggtcatg cattagaatt ggctgtatct
    15181 gaggatatgg ttggtcgtat ttttaatggg atgggaaaac caattgatgg tggaccagat
    15241 ttaattccag agaaatattt agatattgat ggtcaagcta ttaatcctgt atctagagat
    15301 tatccagatg aatttattca gacagggatc tcctctattg atcatttgaa tactcttgta
    15361 cgtggtcaaa aattaccagt attttcaggt tcgggcttac ctcataatga attagctgct
    15421 cagatagcaa gacaagcgac tgttttaaat tctgatgaaa attttgcggt tgtatttgca
    15481 gcaatgggta ttacttttga agaagctgag ttttttatgg aagaactcag aaaaacagga
    15541 gcgatcgatc gttcggtttt atttatgaac ttggcaaatg atcctgcaat tgagcgtatt
    15601 gcaactcccc gcattgcttt aactgcggca gagtatctag cttttgaaaa agatatgcac
    15661 gttctagtta tcatgacgga tatgactaac tattgtgaag cgttacgtga agtctcggca
    15721 gctcgccgtg aagttccagg gagacgaggc tatccgggat atttatatac aaatttatca
    15781 actctatacg aaagggctgg tcgcttagtt ggtaaaaaag gttcggtgac acagattcct
    15841 attttaacaa tgccagaaga tgacataaca catccaattc ctgatttaac tggatacatt
    15901 actgaagggc aaattatttt gtcgcatgag ttgtataatc aaggttatcg tccaccaatc
    15961 aatgttttac cttctctctc tcgattaaaa gataagggat ctggagaagg taaaactcgt
    16021 ggagatcatg ctccaactat gaatcaactg tttgcagcct atgcccaagg gaaaaaggtt
    16081 gaagagttag cagtagtatt aggagaatcg gctttatctg atgtagataa attgtatgtg
    16141 aggtttacaa agcgttttga agaagagtac ataaaccaag gattttataa aaatcgaaat
    16201 atagaagata cgttgaatct tgggtgggaa ttactatcaa ttcttcctag aacagagtta
    16261 aaacgtatca aagatgattt gcttgataaa tacttacctt tggtagaagt ttaatccgga
    16321 aatggagtga ttatctatgg tacgtttgaa tgtaaaacca actcgtatgg aattgaataa
    16381 cttaaaggaa cgtttgacaa cagctgaacg tggacataag ttattaaagg ataaaagaga
    16441 tgaattgatg aggcgattta tttctttgat tcgtgagaat aatcaacttc ggaaagaagt
    16501 ggaaagttat ctaattgata atctaaaatc ctttgcagtt gctaaatcat taaagaattc
    16561 tcaaatggtg gaggaattat tttcaattcc atcgaaagaa attgaattat ttgttgagaa
    16621 agaaaatatc atgagtgtaa cagttcctag aatgcatatg aatattactt ctcaaaatga
    16681 gaacagtgaa tacagctatt tatcttctaa tagtgaaatg gatgatgtat ttgctacaat
    16741 gaatagttta atttataaat tactaagact ggcagaagtt gaaaaaacgt gtcagttaat
    16801 ggctgatgaa atagaaaaaa cacgtagacg tgtaaatggt ttagaatact cgattattcc
    16861 aaacttgtcg gaaactattc attatataga attgaaacta gaggaggcag aaagagccaa
    16921 tttagttcgt attatgaaag tgaagtagat cctttattta gattattaat tagatgaaca
    16981 aatatcagct tggataaggc tttaagcctt tctaagcttt ttttattgac agtatcagga
    17041 tatctttttc aaaattttgg tttgttagat aatgaaaatg tttctactaa tctagattta
    17101 ggattagtaa atcgtaaatg taattatata gaaagtaagc gcgtcataac aaggtatcta
    17161 tcattcatgg agctcctcct gtatactatt agtaaagtaa aactattgga ggatatttta
    17221 atgccacaac ctattgttcc tgtagagatt ccacaatctc gtcgttttga ttctaaaaag
    17281 agaaatgata ttctgcttaa aattcgtatt ggcaagcttg aagtaagttt ttttcaatct
    17341 ctcaatctcg aaatggtaga acagcttttg gataaggtgt tgctctatga caattcatct
    17401 atctagccta ggggaggtct atctcgtgtg tgggaaaact gatatgagac aaggaatcga
    17461 ttcactggct tatctggtta aaacccactt tgaattggat cctttctccg gtcaagtctt
    17521 tctcttttgt ggtggacgta aagaccgctt taaagtcctt tactgggatg gtcaaggatt
    17581 ttggctacta tataaacgct ttgagaacgg cagattgatt tggctaagta cagaaaagga
    17641 tgtcaaagct ctcacaccag aacaagtaga ctggcttatg aagggctttt ctatcactcc
    17701 aaaaatatag tagattgaaa ctagaatagt acacctctgc ttctaaaaca ttgttagaaa
    17761 tcgattttac tgtcctgatc gatttgtcct gttcttattt cattttacta taaatccatc
    17821 agaaagtcgt gatttctatt gaaatgagga ctttcttttt atactcatct gctttcaaaa
    17881 agcattctag tccatctccg attaacgatg gactttatca cctccttctc cagtccttgt
    17941 ataacatctt ggagttgatt catgacatct tccaaagttt aaaaggcttt attcttaaat
    18001 ccacgtttac gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga
    18061 ggaataaatg caaagccaat attagtcgga atctttaagg tacttgattt atgccatata
    18121 gcattgtcca taacgagtaa aagataatca tctggataag cttgtgaaat ctcctattcc
    18181 taaagcccct ttagcgcata actttggctc agcttctatt atcgctcaca ccatccatca
    18241 gaagtttaat ctgaaggtac ccaattatcg ccaagaagaa gattgggcta ggatgggttt
    18301 accaatcaca cgtaaggaaa tctctaattg gcatatcaag gcgagtcaat actatttgga
    18361 gcccctttat aacctcttgc gagagagact attgactcag cccttacttc atgcggatga
    18421 aacttcttat agggtgctag agagtgatag tcagctgact tactattgga cttttttgtc
    18481 aggtaaagca gagaaacaag ggattacgct ttaccaccat gatcagtgtc gaagtggttc
    18541 agtagtacaa gaattcctag gagattattc tggctatgtg cattgtgata ttttgcagca
    18601 gtaacttagg actttagtcc tctagttctg cctatgcgat agcagtccaa ggtttaggag
    18661 caaggcgacg ctaagcttgg taaacttcga accgctcgtc tgcttatcgt caactggaag
    18721 aagctgaact tgttggatgt tgggcgcatg tgagaaggaa gttttttgaa gcgccccccc
    18781 aagcaagcgg ataaatcatc cttaggagct aaaggtttag cttattgtga tcagttattt
    18841 tccttggaaa gagactggga ggctttgcca gctgatgaac gactacagaa acgtcaagaa
    18901 catctccagc ccttaatgga agacttcttt gcttagtgcc ggcgtcagtc agttttagca
    18961 ggttcaaaac taggaagggc aattgaatac agcctcaagt atgaagaaac ctttaagacc
    19021 attttgaaag acggacatct ggtcctttcc aataatctag ctgaacgcgc cattaaatca
    19081 ttggttatgg gacggagtaa aagagtccag tggactcttt tagcctaagc tcagtttaaa
    19141 aaagcgaggg tggttatttt ctcaaagttt tgaaggagct aaagcaagag ctattattat
    19201 gagtttgttg gaaacagcta aacgtcatca attaaatagc gagaaatatc tatcctatct
    19261 tctagaatgt cttccaaacg aggaaactct cgtaaacaaa gaggttttag aggcttattt
    19321 accatggact aaagttgtac aagaaaagtg caaataagaa atctccagat taggaactat
    19381 ccgtgagttc tccagtctgg agatttttca atagacttcc tgcgaaacaa aatatggtat
    19441 agtagttcta tgaatgatga agcaagtaaa caactaaccg atgcacgatt taagcgtctt
    19501 gttggtgttc aacgcacgac ttttgaagag atgttagctg tattaaaaac agcttatcaa
    19561 cttaaacacg caaaaggtgg acgaaaacct aaattaagcc tagaagacct tcttatggcc
    19621 actcttcaat atgtgcgaga a
//
LOCUS       DBERCW010000035        18829 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.035, whole genome shotgun sequence.
ACCESSION   DBERCW010000035 DBERCW010000000
VERSION     DBERCW010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18829
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.035"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            262..1821
                     /locus_tag="ACL72M_001620"
     CDS             262..1821
                     /locus_tag="ACL72M_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0716722.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(1970..2869)
                     /gene="htpX"
                     /locus_tag="ACL72M_001621"
     CDS             complement(1970..2869)
                     /gene="htpX"
                     /locus_tag="ACL72M_001621"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGS0716723.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(2871..3431)
                     /locus_tag="ACL72M_001622"
     CDS             complement(2871..3431)
                     /locus_tag="ACL72M_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGS0716724.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            3525..4238
                     /gene="rsmG"
                     /locus_tag="ACL72M_001623"
     CDS             3525..4238
                     /gene="rsmG"
                     /locus_tag="ACL72M_001623"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGS0716725.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            4541..5824
                     /locus_tag="ACL72M_001624"
     CDS             4541..5824
                     /locus_tag="ACL72M_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGS0716726.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6019..7590)
                     /gene="ffh"
                     /locus_tag="ACL72M_001625"
     CDS             complement(6019..7590)
                     /gene="ffh"
                     /locus_tag="ACL72M_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGS0716727.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(7602..7934)
                     /locus_tag="ACL72M_001626"
     CDS             complement(7602..7934)
                     /locus_tag="ACL72M_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGS0716728.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(8025..8402)
                     /locus_tag="ACL72M_001627"
     CDS             complement(8025..8402)
                     /locus_tag="ACL72M_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGS0716729.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            8474..9778
                     /locus_tag="ACL72M_001628"
     CDS             8474..9778
                     /locus_tag="ACL72M_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGS0716730.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            9791..10597
                     /gene="yidA"
                     /locus_tag="ACL72M_001629"
     CDS             9791..10597
                     /gene="yidA"
                     /locus_tag="ACL72M_001629"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGS0716731.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            10640..11638
                     /locus_tag="ACL72M_001630"
     CDS             10640..11638
                     /locus_tag="ACL72M_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003712 - transcription coregulator
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HGS0716732.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNDLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(11804..11875)
                     /locus_tag="ACL72M_001631"
     tRNA            complement(11804..11875)
                     /locus_tag="ACL72M_001631"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11840..11842),aa:Arg,seq:cct)
     gene            complement(11917..12264)
                     /gene="rplS"
                     /locus_tag="ACL72M_001632"
     CDS             complement(11917..12264)
                     /gene="rplS"
                     /locus_tag="ACL72M_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGS0716733.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(12383..12712)
                     /gene="crcB"
                     /locus_tag="ACL72M_001633"
     CDS             complement(12383..12712)
                     /gene="crcB"
                     /locus_tag="ACL72M_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS0716734.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(12706..13080)
                     /gene="crcB"
                     /locus_tag="ACL72M_001634"
     CDS             complement(12706..13080)
                     /gene="crcB"
                     /locus_tag="ACL72M_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS0716735.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(13077..13343)
                     /locus_tag="ACL72M_001635"
     CDS             complement(13077..13343)
                     /locus_tag="ACL72M_001635"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGS0716736.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(13459..13902)
                     /locus_tag="ACL72M_001636"
     CDS             complement(13459..13902)
                     /locus_tag="ACL72M_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGS0716737.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            14006..14941
                     /locus_tag="ACL72M_001637"
     CDS             14006..14941
                     /locus_tag="ACL72M_001637"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGS0716738.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            15037..15279
                     /locus_tag="ACL72M_001638"
     CDS             15037..15279
                     /locus_tag="ACL72M_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGS0716739.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(15336..15554)
                     /locus_tag="ACL72M_001639"
     CDS             complement(15336..15554)
                     /locus_tag="ACL72M_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716740.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(15551..16302)
                     /locus_tag="ACL72M_001640"
                     /pseudo
     CDS             complement(15551..16302)
                     /locus_tag="ACL72M_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16639..17985
                     /gene="gdhA"
                     /locus_tag="ACL72M_001641"
     CDS             16639..17985
                     /gene="gdhA"
                     /locus_tag="ACL72M_001641"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGS0716741.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(18491..18661)
                     /locus_tag="ACL72M_001642"
     CDS             complement(18491..18661)
                     /locus_tag="ACL72M_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716742.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(18674..>18829)
                     /locus_tag="ACL72M_001643"
     CDS             complement(18674..>18829)
                     /locus_tag="ACL72M_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGS0716743.1"
                     /translation="CTQIIVAHRLSTIKDADVIFVMKGGKIVESGNHKYLMDLGGEYY
                     SLYTKRK"
BASE COUNT         5809 a         4018 c         3388 g         5614 t
ORIGIN      
        1 atggacctgt ttttggattt tagagcatag aatttccagt tttctgttga caaaatttcc
       61 ttaaaggtat aatataaaga tactaatact cggaggtaag ggagacatga acaactaagt
      121 ctatcaaata aagaaccttt atttagtaga tcttgttttt gtctcttttt gtgtgctctt
      181 ttatgctctt tttctggcat gttaatagag tttttttgac atagactttg ggctctacta
      241 ggtaaagtag agctttttgt tatgcactat cgacattcta gaaagggcaa tagtatgata
      301 aaaatcaatc acctgaccat cacacaaaac aaagatttac gagaccttgt ctctgaccta
      361 agcatgacca tacaagacgg ggaaaaggta gctattattg gcgaagaagg aaatggtaaa
      421 tcaaccttac ttaaaacttt aatgggggaa gatttgtctg atttcactat caagggagac
      481 atccaatctg actatcagtc actggcctac attcctcaaa aacttcccga ggagctgaaa
      541 aagaaaactt tacacgacta cttcttttta gattctattg atttagacta cagtatcctc
      601 tatcgtttgg cggaggaatt gcattttgat agcaatcgtt tcgcaagtga ccaagagatt
      661 ggcaatctat cagggggaga agctttgaaa attcagctta tccatgagtt agccaaaccc
      721 tttgagattc tatttttaga tgaaccttca aatgacctag accttgagac agttgattgg
      781 ctaaaaggcc agattcaaaa gaccaggcaa accgttattt tcatttccca tgatgaagac
      841 tttctttctg aaacggcaga cactattgtt cacttgcgac tggtcaaaca ccgtaaagaa
      901 gcggaaacgc tagtagagca tttagactat gatagctata gtgagcagag aaaggctaat
      961 tttgccaaac aaagtcagca agctgctaac aaccaaagag cctacgataa aaccatggaa
     1021 aaacatcgga gagttaagca aaatgtagaa actgcgcttc gagctaccaa agatagtact
     1081 gccggtcgcc tattggctaa aaagatgaaa actgtcctct cacaagaaaa acgctacgaa
     1141 aaggcagctc agtccatgac tcaaaaacca cttgaagagg aacaaatcca acttttcttt
     1201 tcagacatcc aaccattacc agcttctaaa gtcttagtcc aactggaaaa agaaaatttg
     1261 tccattgacg accgagtttt ggttcaaaaa ctacaactaa ctgtccgtgg ccaagaaaaa
     1321 atcggtatta tcgggccaaa tggtgttggg aaatcaactc tgttagccaa gttacagaga
     1381 cttctgaatg ataaaagaga gatttcactt ggttttatgc cacaagatta ccacaaaaaa
     1441 ctgcaattgg atttatcccc aatagcctat ctcagtaaaa ctggggaaaa agaggaacta
     1501 cagaaaatcc aatctcacct agctagtctc aatttcagtt atccagaaat gcagcatcaa
     1561 attcgctcct tatctggcgg acaacaggga aaactcctgc ttttggattt agtcctgcgc
     1621 aaaccaaact ttctcctgct ggatgaaccc acacgaaact tttctcccac ttctcaaccc
     1681 caaatcagaa aactctttgc cacttatcct ggcggtctca tcactgtttc gcatgaccgt
     1741 cgtttcttaa aagaagtctg ctcgatcatc tatcgcatga cagaacacgg tttgaagcta
     1801 gttaatttag aagatttata aatttgcaac atagcagata ggtggggcaa aaacacaatt
     1861 ttaggagaaa aagaagtaaa tcttcccata gtaaaacgca taatatcaag ttttcacacc
     1921 tgatattatg cgtttttcag attttaaaga cttttttcca gccttcattt tacatatgtt
     1981 ttaaacgttc aatccgttct gagataggtg ggtgggtata aaagagtttt tggaaccccc
     2041 cacctttctt gggatcattg atataaaggg cactgctagc atcatcgacg tggcgactca
     2101 taggtttgct attgtccaac ttatctaggg cattaatcat tccctgggga ttgcgagtca
     2161 gctcgacact agatgcatct gccagaaatt ccctctgacg agaaatagcg agctgaacca
     2221 aggttgcagc gagaggtgcc agtacaatag ctagtaggga aaccactagc ataatgattt
     2281 caagaccatt tccatctcgg tcatcatcac ttcgtctgcg acctgctcca ccccaccaca
     2341 tcatacgacc tgccatacta gaaagcatgg tgatagcact agcaagggca actgcaatag
     2401 tcgaaatacg gatatcataa ttacgaatat gactgacttc atgtcccata acagcttcta
     2461 gttcttcacg attcatgata gctagtagac ctgaagtcgc agcaacagcc gcattttgag
     2521 gattagaacc tgtcgcaaag gcatttaagg ctggatcatc aatgatgaaa acacggggca
     2581 taggaatctg agcgaccaga gccatatctt ccactacatg gtagaggtct ggtgccgttt
     2641 gctcatccac ctcacgcgct ccattcatgg acatgacaat ctctgtcgat tgaaaaatca
     2701 tagacaaagc gtagataaag ccgataatca gtgcgataac caaaccacca agtccagatc
     2761 ttataaagag ataaccaacc gcataaccaa caagagctaa gagtaggaaa aataccagca
     2821 acaaaatcca ggtttttcgt ttattgcttg caatttgatc aaacaacatc ttagtcacct
     2881 aaaccgctaa aatcaacttt aggaaccgac ttttcctctt caggtgtttg aaggaaatct
     2941 gccgctttaa atccaaacat tccagcgata atattgctcg ggaaagtttc taattttaca
     3001 ttgtagttgc tgacaacact gttatagagt tgacgagagt aagaaatttt attttctgtg
     3061 tttgtcaact cctcttgcaa tttaacaaag ttagcactag ctttcaaatc tggatagctt
     3121 tctgcaactg caaaaatacc tgaaacttga cgagtgaggg catcactggc tttcatagct
     3181 tctgctggtg aagtcgctgc cgccacttgg ttacgtagtt ctgccacctt ttcaagggta
     3241 gaaccttcat atttggcata accttttaca gtctcaatca agtttggcaa gaggtcattt
     3301 cgacgtttca actgaacatc aatctgactc caagcctcct tggtttgcat acgattttta
     3361 accaaaccgt tatagctaac aatcacaaaa ataacaataa gagcgataac tccaagaata
     3421 atccaagtca tgatataagt cctttctact tttagattag taccagtata tcaaattttt
     3481 aatgattgtg gtaaaataag atgatactaa agaaggaaat aactatgaaa ccagaaacat
     3541 tttacaactt gcttgccgag cagaatcttc cactttcgga ccagcaaaaa gaacaatttg
     3601 aacgttattt tgagctcttg gtcgagtgga atgagaagat taatttgacg gcgattacgg
     3661 acaaggaaga agtttatctc aaacattttt acgattcgat tgcacccatt cttcaaggtt
     3721 tgattcccaa tgaaactatc aaacttcttg atatcggggc tggggcagga tttcctagtc
     3781 taccaatgaa aattctctat ccggagttag atgtgaccat tattgattca ctcaataagc
     3841 gcatcaactt cctacaactc ttggctcaag aactggattt gaacggagtt catttctacc
     3901 acggacgtgc cgaagatttt gcccaagaca agaacttccg tgctcaatat gattttgtaa
     3961 cagctcgtgc ggttgcccgt atgcaggtcc tatctgaatt gactattccc taccttaagg
     4021 ttggtggcaa actattagca ctcaaggcta gcaatgcgcc tgaggagttg ttagaagcta
     4081 agaatgccct caatctcctt tttagtaagg tcgaagacaa tctcagctac gccctaccga
     4141 atagagatcc gcgctatatc acagtggtag aaaagaaaaa agaaacacca aataaatatc
     4201 cacgtaaggc tggtatgcca aataaacgcc cactttaaat tttttagtaa acaaatgttt
     4261 acaaaatcag cctcgctctt ttatttctag gctcgggaaa aaatgattta caaaatcagc
     4321 ctcgctcttt tatttctagg ctcgggaaaa aatgatttac aaaatcattt ttttctgcta
     4381 tactatccta agcaaaggtt tttaatgtca tcccgtgagg tgacgaagac gcagaaatat
     4441 ttgaaactct ttaaagtcta gattttagag aagtcttact ctgagggcct attgctgtaa
     4501 aataatgggc tcttttctga tgcccaaaag tgaggtttat atgaaacaag aatcaactgt
     4561 tgatttgtta ctagacgttg accaacgtcc ttcggatgga aaaggaattc tccttagctt
     4621 ccaacacgtt ttcgccatgt ttggtgcgac catcttggta ccattgattt tgggaatgcc
     4681 tgtatctgtt gccctttttg cttcaggtgt tggaacactc atctacatga ttgctactgg
     4741 ttttaaagtt ccagtttatc taggttcttc atttgccttt atcacagcta tgtcactggc
     4801 tatgaaagaa atgggggggg atgtatctgc tgcccaaaca ggggttatct tgactggttt
     4861 ggtctatgtc cttgttgcta ccagcatccg atttgtagga acaaaatgga ttgataaact
     4921 cttgccacca atcattatcg gtcctatgat catcgttatc ggtcttggac ttgcaggttc
     4981 agctgttacc aatgcaggtc ttgtagcaga cggaaattgg aaaaatgctc tggtagccgt
     5041 tgttactttc ctaattgctg cctttatcaa tacaaaagga aaaggcttcc tacgaatcat
     5101 tccattcctc tttgccatta tcggtggtta ccttttcgca ctaactcttg gcttggttga
     5161 ctttacacca gttcttaaag ccaactggtt cgaaattcct ggtttctact tgccatttag
     5221 cacaggtggt gcctttaaag agtacaatct ttactttggt ccagaagcca tcgctatctt
     5281 gccaatcgct atcgtaacaa tttctgaaca tatcggagac catactgttt tgggtcaaat
     5341 ctgtggccgt caattcttaa aagaaccagg tcttcaccgt actcttattg gtgacggtat
     5401 cgcaacttct gtttctgcct tccttggtgg accagccaat acaacttacg gagaaaatac
     5461 aggggttatc ggtatgactc gtatcgcttc tgtctcagtt atccgtaacg ctgccttcat
     5521 cgcgattgcc ctcagcttcc ttggtaaatt cactgccttg atttcaacta ttccaaacgc
     5581 tgtacttggt ggtatgtcaa tccttctcta tggggttatc gccagcaatg gtttgaaagt
     5641 cttgattaaa gaacgtgttg atttcgctca aatgcgaaac ctcatcatcg caagtgctat
     5701 gttggttctt ggacttggag gagctatcct taaacttggt ccagttacac tttcaggtac
     5761 tgccctttca gccatgacag gaatcatctt gaacttgatc ttgccatacg aaaataaaga
     5821 ctaagagtct aaatacacct aatccactca gacagctgag tggatttttc gtatatcata
     5881 ataaaagtgt cttaacaaaa ttattaaaat caaaaaacgt ataatatcag atattctaaa
     5941 accttgatac tgtacgtttt atcatagaaa tttttacttt attttctcat caaatgagat
     6001 ttgcatcaat ctcttgtctt acttgcgttt cttcttcgct ttcttcattt tgttagccat
     6061 acgtttcatg gactgtttca tggcaaattc accaatttta cctttcaaac cgccaccaaa
     6121 catctggctc atatctggca ttcctgctcc tccgagagct gataagtcag gcataccgcc
     6181 ttgtcccatc attccttcaa gggcagacat atccattcct cccatatttg gcatattttt
     6241 aggaaggtta tttggattaa tccccatttg cttcatcatt ttattcatat ccccagacat
     6301 aacaccctgc atgagctgtt tagcctggtt aaagtccttg ataaatttat tgacttcgac
     6361 gaatgtattt ccagaaccag cagcaatacg acggcgacgg cttggattta acaaatctgg
     6421 gttttcacgt tcttcaggtg tcatcgaaga cacaatggca cgtttacgag caatctggcg
     6481 ttcatccacc ttcatgtttt gaagtgctgg attgttggcc atacctggaa tcatcttgag
     6541 caagtcttcc atcggcccca tattttgcac ctgatctaat tgatcgatga aatcattaaa
     6601 atcaaaggtg ttttcgcgca tcttctcagc catttcaagg gctttttgtt catcgtattc
     6661 ctgagaagct ttctcaatca aagtgagcat atcccccatg ccaaggatac ggctagacat
     6721 acggtctggg tggaaggttt cgatatctgt aattttttca cctgtaccag tgaacttgat
     6781 tggttttcca gtgatgtgac gaaccgatag agccgcacca ccacgagtat cgccatcaat
     6841 cttggtaagg atgaccccag tcacttccaa ctgagcatta aactcacgcg caacattggc
     6901 tgcttcctga ccaatcatgg catcaacgac gaggagaatt tcatttggtt gagccaatgc
     6961 tttcacatca cgaagctcat tcatgaggag ctcatcaatt tgcaaacgac ccgcagtatc
     7021 aatcaagaca tagtcgttat gattagtttg ggcttgctcc aaaccttgac gtacaatctc
     7081 aacagctggt acttctgttc caagtgcaaa gacaggcaca tcaatctgtt gtcccaaagt
     7141 cttaagctgg tcaatggcag ctggacgata aatatccgcc gcaatcatca aaggacgagc
     7201 attttcttct ttcttgagtt tgttggccaa tttaccagca aaggttgttt taccagcccc
     7261 ttgtaaacca accatcatga tgatggttgg aatcttaggt gacttgataa tttctgccgt
     7321 atcagaacct aaaacggctg tcagttcctc atcaacgatt ttaataatct gttgcgcagg
     7381 attaagtgta tcaatgacct catgcccgac tgcacgctca cgaactttct tgataaagtc
     7441 ctttacaaca ggcaaagcaa cgtcggcctc aagcaaggcc aagcgaattt ctttggttgc
     7501 ctcttggaca tcagattcag agatttttcc ttttttacgt agacttttaa agacgttctg
     7561 caaacgttct gttaaacttt caaatgccat ttttcttcct cttattctct attatcaatg
     7621 cttgttaaaa tttctatctg ctcctgcaga aagttatcct tgggatagcg ctccaaaatc
     7681 tgatcaaaaa tctgactgcg gacaatatag tccgagtaca tgtgcaattt catctcataa
     7741 tcttccagaa tcttttctgt tcgcttgata ttgtcataga cagcctgacg actgacaccg
     7801 aactcctcgg caatttcagc aaggctgtaa tcatcagcgt agtagagctc gatataattc
     7861 atttgcttat ctgtcaaaag cgccgcataa aattcaaaga gcgcattcat acgattggtt
     7921 ttttcgattt ccataacttt tattatacca aaaattagcc taatctacca cactaggaag
     7981 ccgatccaag aagatagata gctaaatttg aaaaagacat aagcctagcc ccaagtaatt
     8041 tccaattgat agctggcaaa gggatgtccc tcttgatttt gtagttgata atctagttca
     8101 atcttttgcc catccacttg ataacgattc gtttggataa taaactcctg catacccata
     8161 ggtgtgggaa tataggctaa actatcacta tcctttagaa agcgcataat ggtcttggga
     8221 ttggaaaatc gactcatcac aagttcttga ccatgaaatt taatcactac tttttccttt
     8281 tcctcattat agaaaagcag gtagctataa tctccttttt catgcacttc cacatcataa
     8341 agctggtcaa tcacttccaa ctgctcatca aactgaattg tatttcgcat ccgaatcttc
     8401 acatcaggcc ctctttcttg tctcttgtcc tactatttta ccaaaaagag caggattttg
     8461 ctataatggt catatgaacg aaaaagtatt ccgtgaccct gttcacaact acatccatgt
     8521 caataatcaa atcatctatg acttgattaa tacaaaagaa tttcagcgtt tgcgccggat
     8581 caaacaactg ggaacttcca gttatacctt ccacggtgga gaacacagtc gcttctctca
     8641 ctgtctagga gtctatgaaa ttgcacgacg catcacagag attttcgaag aaaaatatcc
     8701 tgaggaatgg aatcctgccg agtctctctt gaccatgacc gctgctctcc tacacgacct
     8761 tgggcatggt gcctactccc atacttttga aaatctcttt gatacagacc atgaagccat
     8821 tactcaggag attattcaaa atcctgagac agagattcac caagtcctgc tacaagtggc
     8881 acctgatttc ccagaaaagg tggccagtgt cattgaccat acctatccta ataagcaggt
     8941 cgtgcagctc atttctagtc agattgacgc agatcgcatg gactatctct tgcgcgactc
     9001 ctattttaca ggagcatcct atggggaatt tgacctgact cgaatcctcc gagtcattcg
     9061 tcctatcgaa aatggtatcg cctttcagcg caatggcatg cacgccatcg aagactacgt
     9121 cctcagtcgc taccagatgt acatgcaggt ttatttccac cccgcaacac gcgccatgga
     9181 agttctccta cagaatcttc tcaaacgcgc caaggaactc tatcctgagg acaaggattt
     9241 ctttgcccga acttctccac acctcctgcc tttcttcgaa aaaaatgtga ccttgactga
     9301 ctatctggct ctggatgatg gcgtgatgaa tacctacttc cagctttgga tgaccagtcc
     9361 tgacaagatt cttgcagatt tatcgcatcg ctttgtcaac cgcaaggtct ttaaatccat
     9421 taccttttca caagaagacc aagaccaact cgctagcatg agaaaattgg ttgaggacat
     9481 cggctttgat cccgactact atactgccat tcataagaac tttgacctcc cttatgatat
     9541 ttaccgtccc gaatctgaaa atccaaggac acagattgag attttacaaa aaaatggaga
     9601 actggcagaa ctctctagcc tgtcccctat cgtccaatcc cttgctggaa gtcgccacgg
     9661 agataatcgc ttttatttcc cgaaagaaat gttagaccaa aacagcatct tcgcaagcat
     9721 cacccagcaa tttttacact tgattgagaa cgatcatttt accccaaata aaaactaaaa
     9781 gaggaaattt atgagtatta aactaatcgc cgtcgatatt gacggaaccc tagtcaacag
     9841 ccaaaaggaa atcactcctg aagtcttttc tgccatccaa gatgccaaag aagctggtgt
     9901 caaagtcgtg attgcaactg gccgccccat cgcaggtgtt gccaaacttc tggacgactt
     9961 gcagttgaga gaccaaggtg actatgtggt gaccttcaat ggtgcccttg tccaagaaac
    10021 tgctactggc catgagatta tcagcgaatc cttgacctat gaggattatc tggatatgga
    10081 attcctcagt cgcaagctcg gtgtccacat gcatgccatt accaaggacg gtatctatac
    10141 tgcaaatcgc aatatcggaa catacactgt acacgaatca accctcgtca gcatgcctat
    10201 cttctaccgt acccctgaag aaatggctgg caaggaaatt gtcaagtgta tgttcatcga
    10261 tgaaccagaa attctcgatg ctgcgattga aaaaatacca gccgaatttt acgagcacta
    10321 ctctatcaac aaatctgctc ctttctacct cgaactcctt aaaaagaatg tagacaaggg
    10381 ttcagctatt actcacttgg ctgaaaaact cggattgacc aaagatgaaa ccatggcaat
    10441 cggtgacgaa gaaaatgacc gtgccatgct ggaagtcgtt ggaaaccccg ttgtcatgga
    10501 aaatggaaat ccagaaatca aaaaaatcgc caaatacatc actaaaacaa atgacgaatc
    10561 cggcgttgcc cacgccatcc gaacatgggt actgtaaaag tatcattttt caataagaat
    10621 tgattagcaa taaaatccaa tgaatttttt tagcaaacta tttaatttaa aacaaaataa
    10681 tcataataga gacacaaatt ctgattgtaa caatttttac ctaaacgatt tagaatgtgg
    10741 ccttactcct gggcaactca tactcataga ttggactcaa aaaacaggga gaaattataa
    10801 tttcccaaga tattttaaat actctcttca aattgaccct gaatctacac acaatcaatt
    10861 atacaaatta ggatacttca ctaaaaataa gactttatca tatcttacag tagtagaatt
    10921 aaaaactata ttatctaaac ataatttagc tacttctgga aaaaaagcag aattaattac
    10981 aagaataatt aataatgtta acattgacaa tttagatatt ccgttcgaat ttaaactaac
    11041 aaaagaagca caaaatctta ttatcgaaca tagtgactat atcaaagcat actatgataa
    11101 agacataact atggaagatt attgtaaaga aaaaaacaat atctctttta aagcaacttt
    11161 tggtgatata aaatggagtc tcttaaataa acaagctcat aggaatactg tatcaggaga
    11221 ttttggatgc ttatctaaca cacgaaaggc tcagggaaga catttggaac aagaaggtaa
    11281 tattaaacat gctttaatat attacataga atctttgata attactattt caggattaga
    11341 aaacaatttt tcagccactg attatccagt atattatccc gattcgatac ctgactactc
    11401 actaaaacat attcaaacat taatggaatc attatctgat gacgattatg attttgcttt
    11461 tgatgaagca ttatttcgct tctcaatttt gaatgcaaat cattttttat ctaaggaaga
    11521 tattgactat ttaagagtta atttacctcg ttccactgct gaagaaataa acaattactt
    11581 aaagaaatat gaatgttata gtcctttaaa taatttagaa cttgacgatt ttgaataaat
    11641 tgactataca aacatttata tactcgatat agtctcaatt ttatctgatg attgcccaaa
    11701 tttttcaata ataaaacgca taatattatg gagacaatcc cctatattat gcgttctttt
    11761 aatatcaaag actttttgac aaacttcttc gatatctaat tactgccccc tgcaggaatc
    11821 gaacctgcaa ctactcctta ggagggagtt gttatatcca ttgaactaag ggagctagat
    11881 aaaaactctg ctgaaaagca gagtttttta gtcgaattaa cgacggattt ctttgatacg
    11941 agctgcctta ccttgaagag cacgcaagta gtacaatttc gcacgacgta ctttaccgta
    12001 acgaacaact tcgatttttt caacacgtgg agtgtggatt gggaagatac gctcaacacc
    12061 tacaccgtta gagattttac gaactgtgta gttttctgag attccagcac ctttacgtgc
    12121 gataacaaca ccttcaaaaa tctggatacg ttcacggtta ccttcgacaa ctttcgcatg
    12181 tacacgaaca gtgtcaccag gacggaatga tgggatatct gtacgaagtt gaccttcagt
    12241 caagctttgg attaatggat tcattttatt ctcctatctt tgtcaatctt gaggaatctt
    12301 cctcagcgga taaactgtat ttttgtgcgt ccattacaca caagatatag tttaccaaat
    12361 ttctaaaaaa aagtaaagaa atttatagca aaattcctaa aaaaatcgca accaaaccac
    12421 ctatgtaagt caaagtcagg taagaataaa agaccttctt atcacttagc agtctttgaa
    12481 gttcgtcatt caaggtcgaa aaagttgtta aaccgccaca aaatcctgtt gctagaatag
    12541 catatacttc cttagactct acatgattgt agaatactcc aattaaaaaa caacctaaaa
    12601 gattagctat gagcgttccg agtggcaatt tagaagcttg attatagcga gaaaagaaat
    12661 accgtacgag tgctcccaag ccacaggcga ttgcaagata gacgattacc atttcttcct
    12721 ccccaaatag taagctaaaa gcaggcctcc accgatactc aaaagcaaat acagtatcaa
    12781 actaagataa cgccctgtat caagcagctt cacagtatca agcattaggc tggaaaaagt
    12841 tgttaaacct ccgcaaaaac ccgtccccag tgctaaaatc aagcccttac tagtcccctt
    12901 atagaccaga tagcccttga caagataaat caagcagaaa attcccagat agttgacaaa
    12961 gagagtgccc caagggaaat ctggactggc tggtaaccaa gtggaaacta ggtagcggac
    13021 aagtccgccc aacatagcag ctagaaaaat ccctagcgga taaaattgtt cttttttcat
    13081 ttgatatttt gatcctgata atcacgcgaa cgtttgagta tgtccgaaaa agtcgcgaca
    13141 atagtctcct gatagcgctt gtcctctaca cgacttctaa ccttttcaaa aataactgct
    13201 tctctcttag tatctaaaat cggtttccct gaagccttct tataagcgac aactccttca
    13261 actaagtgca ttcgttcttc taacagtttg acaatttggt cgtcgatttg atcgatttct
    13321 tgacgaataa tatctaaatc catacagtct cctcctttat ttgaattatt gtatcaaaaa
    13381 gccatcaatt aggctagtaa aatcccaact ctcgataaga aaaatgcact gattgattac
    13441 atcagcgcac ttttatgctt atcctacttt agcagccaat tcttctgcga attgttccaa
    13501 gcgttcaata tcttcttcct cggcagaaag atcaacttta acacactctg aacctttttc
    13561 tgctcctgtt gacacaaaga cacggtcaaa gtcatcaaca gccttacaaa attcatcgta
    13621 gaaggtatct cctgagccga ccactccgta gattttgcca ttcaagttga gatctgctag
    13681 gtcttcgtag aagtccatca tctcatctgg caattcacca tcaccataag tataggtcgc
    13741 aacgatagcg atgtctgctt ccaagaagtc tgaagcgtca acagttgtac attcatcaac
    13801 atcaacatcc aagcccaagt cacgtaattt gtctgctaca atatctgcaa tttcttcggt
    13861 attaccggtc atactggcaa atacaatttt tgctaatgcc atatcgtcct cctcaattta
    13921 tctttctcca ttatatcaca tctttttcat tttaaaaata aaaattcttg tgctacaatg
    13981 aaatgagaaa gaattgaggt tatttatgga gatttgccaa caaattttag aaaaaattaa
    14041 agaatacgac accattatca ttcatcgtca tatgaaacca gaccctgatg ccttgggaag
    14101 tcaggtggga ttgaaagcct tgctagaaca tcatttccca gaaaaaacca tcaaagccgt
    14161 cggttttgat gaaccaactc ttacttggat ggctgagatg gatcttgttg aagatagagc
    14221 ctaccaaggc gcacttgtca tcgtctgtga tacagctaat actgctcgta tcgatgataa
    14281 gcgctatagt caaggtgatt ttctcattaa gattgaccac catccaaatg atgatgtata
    14341 cggtgacctg tcttgggtcg atactagttc aagtagcgct agcgagatga ttaccctatt
    14401 tgcccaaaca acccaactag ccttggcaga tcgcgatgct gagttgctct ttgcaggaat
    14461 tgtcggtgat acaggtcgct tcctctaccc ttctaccact gcacggactc ttcgcctggc
    14521 tgcttatttg agagaacata actttgactt tgcggctctc actcgcaaaa tggacactat
    14581 gagctacaaa attgctaaac tgcaaggcta catctacgac catctggaag tggatgaaaa
    14641 tggtgctgct cgcgttatcc tgagtcagaa aatcttgaaa caatacaata taaccgatgc
    14701 tgaaactgcg gccattgtag gtgcacctgg acgcattgac agagtgagtc tctggggaat
    14761 ttttgtcgaa caggctgatg gccactaccg agttcgctta cgcagtaaag tccatcctat
    14821 caatgaaatt gccaaggagc atgatggtgg aggccaccct ctagcaagtg gtgctaattc
    14881 ctatagccta gaagaaaacg aaatcatcta ccaaaagtta aaaaacttgc ttaaaaactg
    14941 ataaaatact tgccaaactt ttcagaatct gatagactag tatagtaaca atctatggct
    15001 cgcaaagaga ccatggcaga aaggaaatat tgcaaaatga aaaaagatat ccatccagaa
    15061 tatcgcccag ttgtcttcat ggacacaact actggttacc aattccttag cggttcaaca
    15121 aaacgctcta acgaaacagt tgagttcgaa ggcgaaactt acccattgat ccgtgtggaa
    15181 atttcatcag actcacaccc attctacact ggacgtcaaa agttcactca agcagatgga
    15241 cgcgtggatc gtttcaacaa aaaatacggt ctcaaataat gataagagaa cagttttggc
    15301 tgttcttttt tgtttcttga aatcaactgc tgatttcatg ttccagactc atctgtaggt
    15361 tcgatttcca tgctactagg caggaaggaa atagctgttt caacacgtcc ataatgagct
    15421 atactattgt cacgaaccac actttcattg atggtccaag tggaattcat tttcttaaaa
    15481 gcttctcgga ctttttccaa atctttggag gcaatggcct gctctaaggt ttcaaaacga
    15541 ggacttatac tcatctgctt tcaaaaagca ttctagtcca tctccgatta ccgatggact
    15601 ttatcacctc cttctccagt ccttgtatga catcttgaag ttgattcatg acatcttcca
    15661 aagttcgaaa ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa
    15721 tgggttcatc tctggtgtgt atggaggaat aaaggtaaaa tcaatattag tcggaatatt
    15781 taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaagga taagcttgtg
    15841 aaagctcttc taaaaaggcg ttcatccaca ctccttttta taaacctgaa ataaggcatc
    15901 aattgtaaca aattctcctg cctctgtagc cttcaaatga cgggcaagaa aggctttctc
    15961 ttcctcaact gtcatatatg catggttacg accaccacgt gtttcttgaa ggagagagtc
    16021 gagtccgaac tcctcatatt tttttacgtt tcgccaaatc gttgtttgat tacagtctaa
    16081 aagctctata atctctttat aagatttgcc catcagacga aatatagtag attgaaacta
    16141 gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgtcctg ttcttgtttc
    16201 attttactat agaacgattt gaaggcgttt ataatattta gctgtacgag agtcttttaa
    16261 aagtgttttg atggtttgga tttcttcttt agttgatttc atattactat tatataatgc
    16321 tttttgattt tagtctggta taaatattgc tttcctccaa aatggtcata gttttactgg
    16381 caaatctaac atatcacgga taaattaaca agtgatttct gaattgctaa acattttctt
    16441 ttcttatagc atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg
    16501 tttttttatc tattttcaaa aaaaccaaaa aactgaattg aaagaatttt tagaaaattt
    16561 ctgttttttc tttacagtga aaaaaaattc tgctataatg tcttatgtaa taaaatatga
    16621 caataaaagg agaacgatat gacatctgct aaagaatata tccaaagcgt gtttgaaact
    16681 gtgaaagctc gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga atttttcaac
    16741 actttagaac ctgtatttga aaaacaccct gagtatatcg aagaaaatat cttggcacgt
    16801 attactgagc ctgagcgcgt ggtttctttc cgtgttcctt gggttgaccg tgatggaaaa
    16861 attcaagtaa accgtggtta ccgtgttcaa ttcaactcag ctgttggacc atacaaaggt
    16921 ggacttcgtt tccacccaac tgtaaaccaa gggatcttga aattcctcgg atttgaacaa
    16981 atctttaaaa atgtcttgac tggacttcct atcggtggag gtaaaggtgg atcagacttc
    17041 gatcctaaag gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt catgactgaa
    17101 ttgcaaaaac acatcggacc atcacttgac gtacctgctg gtgatatcgg tgttggtgga
    17161 cgtgaaattg gttaccttta cggtcaatac aaacgtctta accaatttga tgctggtgtc
    17221 ttgactggta aacctcttgg atttggtggt agcttgattc gtccagaagc aactggttac
    17281 ggtttggttt actatactga agaaatgctc aaagctaacg gtaacagctt tgctggtaag
    17341 aaagtcgtta tttcaggttc tggtaacgtt gctcaatatg ctcttcaaaa agcaactgaa
    17401 ctcggtgcaa ctgttatttc tgtttctgac tcaaatggtt atgtcatcga tgaaaatggt
    17461 atcgacttcg atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt gactgagtat
    17521 gcagctgaaa aagcaactgc aacctaccac gaaggtactg tatggactta cgctggaaac
    17581 tatgacattg ctcttccatg tgccactcaa aacgaaatca acggtgaagc agctaaacgt
    17641 ttggttgctc aaggcgttat ctgtgtatct gaaggtgcca acatgccgag cgaccttgat
    17701 gccatcaaag tttacaaaga aaatggtatc ttctacggac ctgcaaaagc tgccaacgct
    17761 ggtggtgtag ccgtttcagc tcttgaaatg agccaaaaca gtcttcgcct ctcatggact
    17821 cgtgaagaag ttgatggccg tctcaaagac atcatgacaa acatcttcaa cacagctaaa
    17881 acgacttcag aaacatacgg tcttgataaa gactaccttg caggagctaa cattgctgcc
    17941 tttgaaaatg tagcaaatgc catgattgca caaggtattg tttaagattt atttactcaa
    18001 tcctcaatca ctacgattgg ggatttttag cttgaattaa aaaattggaa aatctaatta
    18061 aataaaatga aatgaaataa aaactgaaca aattgattgc ggaattcaaa ccaatttcta
    18121 acatatttct agaaattaat ttgacttttc taatcgattt gttcatatct tatttcaatt
    18181 tactatactt acttgaccct ttttatactc aatgaaaatc aaagagcaaa ctaggaagcg
    18241 agccgcaggc tgtacttgag tacggtaaag caaagctgac gtggtttgaa gagattttca
    18301 aagagtatta aacaaaaaga aaaaccgcta ctcctaagaa tagcgattta atcatgtttt
    18361 taagctacta ctgtagttgc tctattattt aagtgttatg aataacttca atatctttaa
    18421 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
    18481 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
    18541 tcaacaagcc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaacacta
    18601 ttccaatcat cactcctagt gaggctgttg ttaaaattac atattcattt tctttcttca
    18661 ttttctttac acctcatttc ctttttgtat ataagctgta gtactctcca ccaagatcca
    18721 ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataacat
    18781 ccgcatcctt aatcgttgac aatctatgag ctacaattat ttgagtaca
//
LOCUS       DBERCW010000036        18684 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.036, whole genome shotgun sequence.
ACCESSION   DBERCW010000036 DBERCW010000000
VERSION     DBERCW010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18684
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.036"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..863)
                     /gene="lytB"
                     /locus_tag="ACL72M_001644"
     CDS             complement(<1..863)
                     /gene="lytB"
                     /locus_tag="ACL72M_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGS0716744.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGG"
     gene            complement(905..1843)
                     /locus_tag="ACL72M_001645"
     CDS             complement(905..1843)
                     /locus_tag="ACL72M_001645"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGS0716745.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKVTNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1854..2654)
                     /locus_tag="ACL72M_001646"
     CDS             complement(1854..2654)
                     /locus_tag="ACL72M_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGS0716746.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2904..3284)
                     /locus_tag="ACL72M_001647"
     CDS             complement(2904..3284)
                     /locus_tag="ACL72M_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0716747.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3342..3701)
                     /gene="rplT"
                     /locus_tag="ACL72M_001648"
     CDS             complement(3342..3701)
                     /gene="rplT"
                     /locus_tag="ACL72M_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGS0716748.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3753..3953)
                     /gene="rpmI"
                     /locus_tag="ACL72M_001649"
     CDS             complement(3753..3953)
                     /gene="rpmI"
                     /locus_tag="ACL72M_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGS0716749.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3986..4516)
                     /gene="infC"
                     /locus_tag="ACL72M_001650"
     CDS             complement(3986..4516)
                     /gene="infC"
                     /locus_tag="ACL72M_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGS0716750.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4532..4663)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4823..6004)
                     /locus_tag="ACL72M_001651"
     CDS             complement(4823..6004)
                     /locus_tag="ACL72M_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716751.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKMQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     gene            complement(6008..6595)
                     /locus_tag="ACL72M_001652"
     CDS             complement(6008..6595)
                     /locus_tag="ACL72M_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0716752.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6628..6852)
                     /locus_tag="ACL72M_001653"
     CDS             complement(6628..6852)
                     /locus_tag="ACL72M_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716753.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYDSYSEYPVGSGWNYGRYEIINYYSGGY"
     gene            complement(6994..9234)
                     /locus_tag="ACL72M_001654"
     CDS             complement(6994..9234)
                     /locus_tag="ACL72M_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGS0716754.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPLSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9218..9868)
                     /locus_tag="ACL72M_001655"
     CDS             complement(9218..9868)
                     /locus_tag="ACL72M_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HGS0716755.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            complement(9936..10505)
                     /locus_tag="ACL72M_001656"
     CDS             complement(9936..10505)
                     /locus_tag="ACL72M_001656"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716756.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNSASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10682..11793
                     /gene="ald"
                     /locus_tag="ACL72M_001657"
                     /pseudo
     CDS             10682..11793
                     /gene="ald"
                     /locus_tag="ACL72M_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12094..12420)
                     /locus_tag="ACL72M_001658"
                     /pseudo
     CDS             complement(12094..12420)
                     /locus_tag="ACL72M_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12423..12923)
                     /locus_tag="ACL72M_001659"
     CDS             complement(12423..12923)
                     /locus_tag="ACL72M_001659"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0716757.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13116..14084)
                     /locus_tag="ACL72M_001660"
     CDS             complement(13116..14084)
                     /locus_tag="ACL72M_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGS0716758.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14170..14385)
                     /locus_tag="ACL72M_001661"
     CDS             complement(14170..14385)
                     /locus_tag="ACL72M_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGS0716759.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14394..15248)
                     /gene="cvfB"
                     /locus_tag="ACL72M_001662"
     CDS             complement(14394..15248)
                     /gene="cvfB"
                     /locus_tag="ACL72M_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGS0716760.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15308..15865)
                     /gene="frr"
                     /locus_tag="ACL72M_001663"
     CDS             complement(15308..15865)
                     /gene="frr"
                     /locus_tag="ACL72M_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGS0716761.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15874..16611)
                     /gene="pyrH"
                     /locus_tag="ACL72M_001664"
     CDS             complement(15874..16611)
                     /gene="pyrH"
                     /locus_tag="ACL72M_001664"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGS0716762.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16695..18029)
                     /gene="trmFO"
                     /locus_tag="ACL72M_001665"
     CDS             complement(16695..18029)
                     /gene="trmFO"
                     /locus_tag="ACL72M_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGS0716763.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18275..18547)
                     /locus_tag="ACL72M_001666"
     CDS             complement(18275..18547)
                     /locus_tag="ACL72M_001666"
                     /inference="COORDINATES: protein motif:HMM:NF036719.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS0716764.1"
                     /translation="MFTCFIIHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSG
                     KIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            18524..>18684
                     /locus_tag="ACL72M_001667"
     CDS             18524..>18684
                     /locus_tag="ACL72M_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS0716765.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDL"
BASE COUNT         5396 a         4229 c         3451 g         5608 t
ORIGIN      
        1 ccaccggatt tgaagtagta ccaagcttga ctatgagaat cgtagaccca ttctttttca
       61 gctattttcc catcaaactt gaggtaaaac caagattcct tatcccaaat ccattcattg
      121 gctgccatgt agccaccgga ttttagataa taatagtgac cattctcgaa aatccattct
      181 ttatcagcat agtttccatt ttctttgatg taaaaccaag attggtattg tttgtcaaaa
      241 agccaacctt gctgtacttt ggcaccacta gcattcacat aagcttgatt aatccactga
      301 cttgtcagta gataaccacc ggatttgaaa taatagtcct tccctttaat ttggagccat
      361 tctttctctg cgtgctgtcc atctgctttg atataaaacc aagcatcgta ttgagaatca
      421 tagacccagt cttctattac tttggcacct gttgcaccaa cataggaagt tcctacccaa
      481 gcatttcttt tcatctttcc atcttggtca agataataaa aggctccctt gtcttctacc
      541 cattctgatt tggccatata gccaccagat ttgaggtaaa aatagtcgtc accttgcttt
      601 agccattcat tttcagcata gttagcatct gcttttatat agaaccaaga ttgataatga
      661 gtatcaaaaa cccactcatt cgctgcttga ctgccatctt ctttcagata ctgttttcct
      721 tgccaagtac catcactagc cattgcaccc tctggactag ctaagaaaaa tagcagagct
      781 aaaaaaataa atcttacttt cttcattaac cttcttcctc tgttcttatt tattttattg
      841 taccaaaatt ctcctaaatt catattacaa actaataaaa aatcaagaac agattgattg
      901 cagtttacct cagagactct tttacttcct gacggagttc ttccagactg ctaataccgt
      961 atttatccat gacttttggt aaattttcga tgatgtcagg gcaggcataa ggattggtaa
     1021 agttagctgt tccaactccg atagcagatg ccccagccag atacatttct agggcagctt
     1081 cagccgaatc cactcccccc attccaatga taggcaggtc tgttgtttgg gctacttggc
     1141 ggatgagttt gagggctact ggaaagactg ctggacctga cattccacct gttccattgg
     1201 ccaagattgg ttttctggtt ttgaggtcaa agcgcattcc aaccagagta ttgatcatgg
     1261 tcaagccact tgctcccgca tcttctgcag cttttgcgac agtaacgata tcggtcacac
     1321 tcggggttaa tttgacataa actggcactt ctgaggcttc cacagctgct ttcaccacat
     1381 cataagccaa atctggatct tgaccaatca aaagtccatg attacagtgg tcaacattgg
     1441 gacaagaaat attgagctcg atagctttta cattagttac cttggaaatc ccatgagaaa
     1501 cagctgcata ctcttgtttt gaaaaaccag ctacattggc aataatagga agatttggat
     1561 attctctttc cagccaaggt agcttttcag ccaaaacaac ctctaaacca ggattttgca
     1621 agccaattgc attgagcata ccagcaggcg tctctgccac tcttggagtt ggatttccaa
     1681 aacgtggttc aagggttgtc gccttgatca taatagaacc taaaaggtct aaatcatagt
     1741 acttggcata ctcttgtcca aagccaaaac agcctgatgc tggaataatc ggatttttca
     1801 aatccaaacc aggtagagaa acttgtaatc gatttgtagt cataattttc tccttataat
     1861 acaactgttc ctgtgcggaa aacaggacca tcttcacaga cgcgttggct gaccgtctcg
     1921 ctttctggta cttttagaac acaggcatag caagctccca tcccacaagc catacgagat
     1981 tccagagata aataggctct tgggtgatca tcaaaggttt gattgatata cttcatcatt
     2041 cctggagccc cacacgagta aacagcatca aactgactgt ctaaatcatt gataacaacg
     2101 gaaacatttc ccttgatgcc ataagaacca tcatctgtcg ttacaaagac ctgaccatac
     2161 tgagccaatt ccgttttcaa aataacagca tccttattag caaaaccgag gactgtcact
     2221 actttcactc cacgttcatg caattccttg gccacctcaa gcaagggtgg aacaccaatc
     2281 ccaccaccaa caaggagaac ctgattctgc tcatcaaggt cagacaagtc aaaaccattt
     2341 ccctgaggcc ccatcacatc aagagtgtct ccctgactta aggttgaaaa aattgcagtc
     2401 ccagctccct caatccgata aatgaggtga cactgcttgt ttgccttgtc aatagacgaa
     2461 attgaaatag gacgacgtaa gagatgggca tcgtctggta cacgcagatg aagaaattgg
     2521 cctgctcgca tggcttcaac catttctcct tctaggacta attcaaagat tgctggcgcg
     2581 atttcctctt gtgcaaccac cttcatggtt tccaaccgaa tgacacccaa acgcttctta
     2641 catgtgagat tcataacttt tcctccttaa attttaaggg gaccagataa agaaaagacc
     2701 ttgctagtgc aaggcctcag ttaaaatcgt acaacacaag agagcacact caaaaggtct
     2761 cctctagaaa cttgcactat tcttttatct gacaccttgt gagtctctct ggactcccct
     2821 taaaggttga atttttatta gtatactctt tcagctaaaa aaagtcaagt agaaaacgaa
     2881 tattctactt aacttgcacg aaattatttt tcacgaatga cttcgacctt atatccatca
     2941 gggtctttaa caaagtaata gtttggtgta gttcctggta gaccatttgg ctcagtcact
     3001 tcatagcctt ttgcactgtg ttcttgatga agtgcctcaa gatcaggtgt actgagggcg
     3061 atatgggcaa acccatcacc aaccacatac ggaccgtgat cgtagttata agtcaactcc
     3121 aactcataat catcaccctc aagacctaga tagacaatcg tgaaggcatg gtctggaaaa
     3181 tctctgcgac gcaattcttt aaaaccaaaa gcatcttgat aaaatgcgat tgatttttca
     3241 agattttcta ctcgtaagca agtgtgtagc atttttgaag ccatatcttt ctcctttatt
     3301 tttaaaaaga ctggacaatc ctgttccagt ctcatcagtt gttatttacc aagttttgct
     3361 ttagctgcat ctgcaagagc tgtgaaagct actgcatcgt taacagccaa gtcagcaagc
     3421 attttacggt taacttcgat ctcagccaat ttcaaaccat gcatcaattg tgagtatgaa
     3481 agtccgttca tacgagccgc cgcattgata cgagtaatcc acaatttgcg gaagtcacgt
     3541 tttttctgac gacggtcacg gtatgcatag tagtaagagt tcattacttg ttcttttgca
     3601 gtacggaaca agatgtgttt agctccatag taaccttttg ctaatttaag aatacgttta
     3661 cgacgtttgc gtgatacaac gccaccttta acacgtgcca tgttttattt cctccaaata
     3721 ttttctagaa ttgtttactt acagtcaagc tattatttca agcgagtaag cattgctttg
     3781 atacgtttgt aatctcctga atgcaccata gatgctttac gaagatgacg acgttgtttc
     3841 ttagtttttc cgtggaaacg gtgagaagtg taagcacgga aacgtttaag tccaccagaa
     3901 cctgtacgtt tgaaacgttt agctgatgcg cggtgtgttt tttgttttgg catgattttt
     3961 tctcctttat ttaactttct gacaattatt ttttgtcagt cgctggcgcc aattgcatga
     4021 acatttgacg tccatccatt ttagcacgtt gttcgatgat ggcaatatct tgagttgctt
     4081 cagcaaactc ggctaaaact tttgcaccaa tctctttatg ggtaatcata cgacccttaa
     4141 agcgaataga taccttaact ttatttcctt tttcaaggaa cttacgtgca ttacgaagtt
     4201 ttgtatcaaa gtcacccttg tcaattgttg gacttagacg aacttctttc acagtaacaa
     4261 cgctttgttt tttacgttgt tctttttgct tcttctggta ctcaaatttg aacttaccgt
     4321 agtccataat ttttgcaaca ggcggtttgg cttggggttg aatcaatact aggtcaacat
     4381 tagcgttatc agccaaagct tgcgcttcac tgagtggctt gatgcctagc tgttctccct
     4441 caagaccaat caagcgaact tcacgtacac gaatctcatc attgatgaat aagtcttgct
     4501 ttgctatggt tttcacctct tttgttttat tagagaaaaa caatagcgga ctcgtaaata
     4561 tacaagcccg cacgttatga tagcgtttct tcgaaacttt tcatccgtag ggccaggcaa
     4621 cttaatgtca caaggcgaga agctctcact tctgcttttc tcaactttta tatgatacca
     4681 agttttctag ctcttgtcaa gataaaaagt tattttttga aaagtttgtg tttgtatttt
     4741 ggtttggttt tcgaatcaaa aagagagaac caagttgatt ctctccctat gttagttttt
     4801 ctttagcttc cctataggaa aactaaactt taaaaacttc ctttttacgt gaacttcccc
     4861 atctttcgat aaatagaatc cccactaaca aaaggataat caggcaagga agtaagacca
     4921 tccccatgct ccaatttaga tcgacattat caatctgctt aggtaatctt ccagataaaa
     4981 tctccactga acgcaagtaa gtaaagggaa tcagatgtgc aatcttttga agaggctgaa
     5041 tggtttggat gccaaacaat aagccaacaa tcccaatgag tgaaagaaag aggacaggca
     5101 ttttttgctt gaaaaagtaa gcaatcaaat acacaacttc cacaatgacg ataaaggcta
     5161 agaaagctaa gagcaagcca ggaaataata catcctgcat ctttccaata gttacctctt
     5221 gattcactaa gctataaatc gggtagggat aatctaactg tccaaaacca cttatcagac
     5281 ttcccactag aaaagaaaag ccacagattc cgataaacag cacagttaca tatcccactc
     5341 caactccaag agaggatatt gcaaatgtca cttttgaaac aggatataag tgagctgtgt
     5401 ccagatgatt ttgatatctt tctgcaaata gttgtgttag cataaaaata atcgcaacca
     5461 caaacaagct tgggatgata acctctaaaa tccagacaat ctgatcaatc ccgtgggtcg
     5521 gaaactctaa agtatgtgct tttatgttca agggatacag ggcttggtaa atcttccgtt
     5581 cgcggtcaac ccccattttt aagccagagc tagcagtcgg gtcatttgat acaaattcat
     5641 aattcttctc ttcatcttgc cactgcaaat agtaggcttc tttccagcgc ccttctttta
     5701 gtaaagttag aatttctgtc tttcgcgtca aaagattttt ttgcacgtct aaattatttt
     5761 tagcaaactg gtattcctcc gagctggtat cagacatttg ggagagtttc tcttcatttt
     5821 cattgatagc cctctcgttg gctgcaatgc gactttccaa cctgctctcc aagctgtgtg
     5881 agtttgcagt ctgactattt aaataaaagg taacaccgag tacagataca aataaagcta
     5941 agacaatcca gtttaagcgg cttttgaaaa cttttttcaa taaaaataga ctaacatctt
     6001 tcataaacta aacctcttct atctgcccct gatgaatggt tactactcta tcgcagacat
     6061 caaccaactc ttccttatag tgggaactta aaagaaccag ctgttcttgt ctatcgattt
     6121 gtgctagcct atcaaaaaac ttctgtcgat aatactcatc taagccattt gtaatctcat
     6181 ccatgagcca gcatttggcc tgactgagga aatacatggc aatcaccaag cgttgcttca
     6241 tgcctaagga atacttgcga atgggaagac tgatatagtc agacatttcc caataggcga
     6301 tttcatccct caagttcaga cctgacttcc agatgttttt gataagacga aggtagtcca
     6361 tcccacttaa gtttccatcc agccattcaa tactctcata ataaaataaa gaaggagggg
     6421 ctgcgatatt tccactactt atgggaatta aattgctaat ggcacggaac agggtcgtct
     6481 ttccagagcc attgatagca agaagaccat aaaccctacc ctttttaaag gtgaaatcca
     6541 catcttgcaa gatgacttgt cgcgttttta aggtcacatg agtaagctgc aacatatcta
     6601 gccctccttt ttctcactct ttaagaatta atagcctccg ctgtaatagt ttatgatctc
     6661 ataacgaccg tagttccagc cagaaccaac tggatactca gaatagctgt cataacgaga
     6721 ccatgacgga atccaagcat actgatggtc gtgatagttg gtactatatt cccaaaccgt
     6781 attccaatca tacttgtaac ttttagtgac tgtcacagca gatatactgg actgaaaaag
     6841 accaataatc ataaactaac taattaaacg atttttgcta atttttaatg attttatatc
     6901 ctcaatattg aatacgtttt cattatacca tttttatcat tattatgcaa caaattttta
     6961 gtttatttca ctaatctaca acatttatcc ttcctatcga acactttcga ttttccaact
     7021 atccaacccc ttaaaacgta tagctccttg ctggtcagtt cgataaactt tgctattgat
     7081 accttccagt cgtgtcaatg tttcctgatg ggggagtttc attcgattgc tctttccaac
     7141 tgagataaga gtaagctctg gtttgagttt ttctagaaag gctggacttg atgatttttt
     7201 attgccatgt tggctagctt tcaaaacatt tactttcaag tctggatagt gcttcagcaa
     7261 gtccttctct cctttctcct ccaaatttcc cgtgaagaga aattgcttat ccaagaattt
     7321 cccatacaga actagggtat catcgtgtcc tccatctccc attttccttg gagatagaac
     7381 ttctaactga cttccaaaaa tgggcaagtt ctcccctact gtcatactac gcacctttgt
     7441 ttgagtcgcc tgtagttctg ccacaaattc cttctgtttc agactgtctt ttgatactag
     7501 aatctcccct acatggaaag ccttggtcac ctctgacaaa tctccaacat gctccttgtc
     7561 cgtgttagtc aaaattagct ggtcaatctt agctactcct cgacttttga gatagggaat
     7621 caaggttcgc tgggcattgc tggtcgtcat tttttcttgc catttttcga ttttcttata
     7681 agattctgcc ttaccaccta catctatgag aatggttttc ccagttacat cccgtaggaa
     7741 aatactttct ccttgcccca catccagcat ggtgatttca ttttccagtg gatgcttggt
     7801 caggagaaag agccctgtaa tcaataagca caataccgtt agctttttaa tgttttttct
     7861 caaatcatag accaaagcca aggaaattaa caataggatt aaaaaccatg cattgggttg
     7921 tccaaagacc agaggtctac ttgtcacctg tgacaccaag cgaataatgc cctccaacca
     7981 ttcaaagata aagttcagct gaatgactgg atagagaaag gaaaggacaa ataaaataga
     8041 caagagcggt aagaaggtca agtcaaatag aaaggaaaag acaaaggtca aaaggataga
     8101 caaaggttga aattccgcaa aatagaagga tagaatgggc aatatgccca aggagatgac
     8161 tagactttca ctagtaacag ccttgagccc ctccccttct ttgctggtca tggtcaggat
     8221 aaaagcataa gcgcaggaca agactcctcc tgctgtcaag aaaaagtttg gcatgacaat
     8281 aaagaggaca agcaccgtca aggcaaaatt atccaagccc ttaaccccat gttgagccag
     8341 tagcttttgc aagagactgc gaataaccga tgctgaaaat ccagttagtc ccgcatagat
     8401 aagggaaaag ggataagtca gccatttcaa cttttcttgg gtcaagccca atcgcaagag
     8461 aagtttctta aatccattca tgaaaaaacc tacctgcata ccagataggg caaagaggtg
     8521 gataattcct agactggaat aaagctcatt catctcctca aagtcggtgt ccagatgtcc
     8581 cagcaagagt cctgtcatgt aattgcgcat agggtctgga aagtgcgtct taatccaaac
     8641 cacagccttt cgacgtaaac tggacaagtt ttctcctata tcccaactgc caatcttttg
     8701 aagtgactgg attgttttga tattgagagt ctggtaaatt ccctgagtct tcagataggc
     8761 ttggtaatta aagccaccaa aatttctctg cccttctggc tccgaaagct tcccttctag
     8821 tcctatctca tgcaggtcgg ttaaagcttg aaaggcttct ttctcctcct cggactggag
     8881 tttataatag acttggaaag cacgaccgtt agacttgcca cgaaaggata gactatcacc
     8941 attaacctta atagtatcag gcaaaatccg taccctttca acagaatccg ccagattttg
     9001 actcgcttga ctctgttgcc aattttgaaa aacaaaccaa aatccaaaga ttccgcaaat
     9061 tattagaact ttaccagcag atttccacgg aaattggata aagagacaga ctagcagaaa
     9121 aacaaagccc aacaaagcaa gataagatgc tgagaaaata gcgtaataaa gccaaagtaa
     9181 tagaaaactc aggtaaatta ggggaataga gaaattctta atccactgta acatagtctt
     9241 taagcttttc tattgttttg ccaccaatgc cagagacctt cttgagctcg tctactgact
     9301 tgaacttgcc atttgcctca cgatggtcga taatgtcctg agctcgtttt cctcccagtc
     9361 ccttgacctg cttgagttct tccagactgg ccttgttgag attgaccttc ttttccttgc
     9421 ttattgaaga agctgtcccc gaaccagtct gttgactaac tgcttcttct cccttagtag
     9481 gaacgtaaac cagagcctca tcactaactt tctgagctag attgagcgac ttgctgtctg
     9541 cttgctctgt caagccacca gccttctgaa cagcatcatt gactcgacta cctacaggca
     9601 agtcataaat ccctggcgat ttgacagcac ctttgacatc tactgtgatt agatcttgtt
     9661 caaggggttc ttccttctct tccttgttca cttccttttc ggataccaaa tccttggaaa
     9721 cagctgcaac ttcagcctgc aaattcgttt cctttacagg tgtttgtgga gctggcttta
     9781 gcaggaaaaa tccgcctaca agcaagccca gaccagtaca gatgacgatg attttatact
     9841 ctttgatttt ctcgataatt gcttccatat tttctcctct cttagattat tcgtaagagg
     9901 aagaaaaaac agtcgaaaaa tttcttttca actgcttatt tatttgcaaa atagtcttcc
     9961 ttggtcaaga cataatgaac tcttgtcacg attcggcctt tttcatgctg gtccatacaa
    10021 gcatatggtt ctgcatggga aaaacgcatg cctgatttct ccatgacctt tcctgacgca
    10081 gaattgtcct tatcgtataa agcaactaac ttattcattc ctatcttctc aaaagctagc
    10141 tcaatcacag cacgattggt ttctggcgtt aatccttgat tccaatactt tttattgata
    10201 atgtagccaa tagctgcctt cttaagaaca ggatcaatct tgtgtaagtc aatagttccg
    10261 ataaacttgc cgttatcttt taattcaatc ccccaacgtc ccaagggatt agccaagtag
    10321 aactgagcaa tgttattctt ggtttcttcc aagctttgat tggttggaaa agtgtaacgt
    10381 gtattaccct tgtccgaggc atagtcaaac attgcttccg catcatccaa agttacaggt
    10441 ctaagcaata aacgctccgt ttctatagac ggatactggg caaatttcac aaatattgat
    10501 tccatacttt tccctccatt agagcttgat tttcactagt ctagcataaa aaaatttgga
    10561 tgacaagttt ttcttgattt ttgaagcggt ttcatataca atgaaaccgt cacatttttg
    10621 atttatgaac tggaatgtga caaccaaaac aagaccgtca attgaaaggt aggttatctc
    10681 aatgttaatc ggaatcccaa aagaaattaa aaataacgaa aaccgtgtcg ccctcacacc
    10741 tgcaggtgtt catagcttag ttagtcgtgg tcatcgtgtc cttatcgaaa caaatgctgg
    10801 tctcggttct ggctttactg atgctgacta tcaaaagcaa ggagctgaga ttgtcgctac
    10861 tgctggtgaa gcttgggcag cagagttggt tgtgaaagta aaagaacctt taagttctga
    10921 atacggttac ttgcgcgacg atcttcttct cttcacctac ttgcacatgg ccgctgctcc
    10981 agaattagca gatgctatgt tagcagcaaa aacaacagga attgcctatg aaactgttcg
    11041 tgacaatcaa ggacaactac cgctcctcgt tcctatgagt gaggttgcag gtcgtatggc
    11101 tgtttaaatc ggagctcact tccttactaa gcaagctggt ggctctggtg ttctacctag
    11161 tggtgtacca ggtgttccaa aaggaaaagt aactatcatc ggtgatggtg tcgtcggtac
    11221 acatgctgcc cgcatcgccc ttggtcttgg tgctcaagtg actattttag atattagtgc
    11281 caagcgtctc tcagttctag aagaagtctt tggaagtcaa attcaaactc ttatatctaa
    11341 ttcattcaac attgaagcaa gtatgagaga tgctgatgtg gtgattggag ccattctcat
    11401 ccctggtgca aaagcaccgg aattggtgac agatgagatg gtcaaacaaa tgcgtccagg
    11461 ctctgtatcg ttgacgttgc tgttgaccaa ggtggcgtta tcgaaacagc tgaccgtgtg
    11521 acaacgcacg atgaacccgt ctatgaaaaa cacggtgttc tccactatgc cgttgccaat
    11581 atccctggtg cggttgcccg cacttcaacc atcgccctaa ccaatgtcac tcttccttat
    11641 atcgaagctt tggctggcaa aggattcgca caagcaatct ctgaagatga aggcttgcgt
    11701 caaggtgtga ccacttatca aggttacttg actagcctac cagttgctca aggacttaat
    11761 cgtgactaca ctgatatcaa tgatttagta taaattttga aaagaaaagg gtgacttcgc
    11821 aagtcctacc cactgtgctt tgtgtcatca gctattacat cgttggttta ttgtactgta
    11881 tactttgcaa ctggagactt tcgttccaga ctcaattgtg cataagaaac tctaaattga
    11941 ataaagtcaa cagagtttcg cccaaccact tcgtcttgta atgacaatta tataaaccaa
    12001 aggaagctga gctctttagt cccagcttct ttttatatat aaaattttac ccgtgcaaag
    12061 acagggcctt agcagacttc ttttttactt cgttcaccct tgctttttct ttttaggttt
    12121 gggcgttggc agttggttat acatagctaa aatcaggtct tatagaaaca tcttattatc
    12181 aagttcttcc actcaaatca tttctttggc acctttgtat ggaaactcaa aagaagattg
    12241 gtcaatctta tctaagactg cttgcacggg tttaactaaa aagcgatcgt cataaatgcc
    12301 gccaataatc ttgccgcgga agtaaagaat atactccccc atcatggaac ggtaagtcac
    12361 atcatctaat cctgataatt gttccaaaac aaattccaaa tagttcttac ttgatgccat
    12421 ttctaatctt ctaggctctg ttcagcgata acaaccgtat agagttcttg cttaacctcg
    12481 catccaattg atttaaagcc ctgcttttcc caaaaatgct gagattgcgg atttccctta
    12541 acataagcca aacgtgcctt tcgaaagttc ttagcaaaat aagctagtgc ttctgtcaca
    12601 atatgactac caatcccttt cctctgatag gcttgatcaa ccataaacaa accaataaaa
    12661 acagtctcct catcaggatg tgcatagaca aaatctataa cagccacaag gtcagatcca
    12721 ttccaaaatc caacaaaaaa cttatcagcc ttagctttac cttcaggtag acaaagcatg
    12781 tcctctttta cagttgcaaa atttggctct ggtggacaat gctgaaaata cagaggatta
    12841 ctttcatata aagataaaat acttggaata tccttttcag ttagtatcct acaactgtaa
    12901 tacttagata gttggtcaat catcttttca aattcctact ttcttgtgca ctgtgattat
    12961 gacacaggaa gatgcactga tcgtcatcag ccacataaaa gttctttcca tcgtgcctaa
    13021 tcgttgtctc aaacctttgg ataaaacctt tagcctatac aactggattt tcctctctca
    13081 aaagtatatt cttttgcagg caaacttcct caaaatcagt cgtgtgcaac ttcagtagaa
    13141 tattcatagg ctcggataat ctgagcgaca actggatggc gaaccacatc cttggctgaa
    13201 aaatgaacaa agtcaatctg atggatgttc ttgagtttct cttgagcatc aatcaaaccg
    13261 gacttgacat tacgtggcag gtcaatctga ctaatatctc cattgacaat catcttagaa
    13321 tgaaaaccta aacgagtcaa gaacatcttc atctgcatga tggtcgtatt ttgcgcctca
    13381 tcgagaatga caaaggcatc atccaaggtc cgtccacgca tataggcaag gggcgcaatc
    13441 tcgataattt cacgctccat gagtcgagtt gtttggtctt tccccagaat ctgatacaag
    13501 gcatcgtaaa caggacgaag gtaaggatcc accttctcct taagatcacc cggaagaaat
    13561 ccaagactct ctcccgcttc caccgctgga cgagttagga taattcgctt gacttgccca
    13621 cgtttaaggg cagtcactgc caaggtcact gcaaggaagg tcttccctgt acctgctggc
    13681 ccaattccaa aggtcacatc atgctgtttg acactgtcca cataaagctt ttgccctagg
    13741 gttttgacac ggataggttt cccagtatta tctttgataa tttcttcttc gtaaagggcg
    13801 acaaacttgt caatttcatc atttttgacc atgctaatcg cagtgactac atctggcgta
    13861 ccaacggtca tcccacgatt taccaagacc atcaaagcct gaataacttg acgggcttcc
    13921 tcacaggcag actcttctcc caaaacctgg acaatctccg tacgagcatg aatcacaaca
    13981 tcaagctctt cttccatcaa acgaagatgg cgttcattgg aaccaaaaag atgaaacagg
    14041 tcatctggat gactcagttg aatgtctatt gaatgttcct tcaaataaag aacctctcta
    14101 atccttttat ttctttttat tatagcagag ggatggagaa attactagcc caaacccaat
    14161 gaataaatgc tagtgttcta gatattcctg ccaaatgctg tcaaaatctc ctaggttaaa
    14221 agagaaactg gcatgctcct ccaaaaagcg actgacctca tcaaaatcat ctgtatgttt
    14281 tggaaaagct gcctcttcaa aagcgaggtc tgccaaaatt gctttgggac tgttactttt
    14341 aggattgcgc tcggtcatga gccaagtgta aaatgatttt ctcataagcc tccctaaatc
    14401 aactctgtcc caaactggtc ctgcttgatt ttaccagcct tcataagacc acctaaagct
    14461 ttcttgaact gacctttaga aatgccaaag gttgccttga tgtcgtctgg agatgactta
    14521 tcatttaagg tcatgaaacc gccattactt tccaaataag tcaaaatcat ctgagcatcg
    14581 ttttccaaca tttcaaagga gcgtggtttg agggagaggt tcagagtgcg gtccacttca
    14641 cggaaaccaa taacgcgcgc atctaatact tgccccaaac gtggctctgc gtaacgctcg
    14701 ctaggatgaa taaaaccaag catattattt tctggtaggt aaacaaaagt tcctgacagc
    14761 ttgagacggt aaacaatggc tggccagttt tggttctgca tgttgttgta ggcaggacga
    14821 gcaagacgtt ggaagtcttc ttgataagcc aagaggcccc agatacggtc tttcttatcc
    14881 acttcaagac ggatgtagag ttggtcgccc ttcttaggcc agagttcctt gagctcaggg
    14941 agaatatcga gtgacacaac gatttccttg tcaggaaggc ctgtatccac aaagacaccc
    15001 aaatccttac gaacctctgt gacacgtccc caaccaaatt ggtcctgagt ggcagtcact
    15061 tctaaggttg tcaggcggag tttttgcttc atatccgtgt atgcaaaacc tttgaccgta
    15121 tcccctactg tatgttgacc ttcttcctta gcaagagcat aggtttgacc atccttttgc
    15181 acaaagtaaa aacggtcatt ttcatcgatg atcagtccaa cgataaaact tgcaagattt
    15241 gtattcatat ttccttcttt cgaataaaac tcagccagca atgccaactg agtttttctg
    15301 tttattttta gacttccaaa agttctttct ctttgttagc agtcatgtcg tcgatgtgtt
    15361 taacagcatc gtctgttact ttttgaatat ctttttcaag agtcttcaat tcgtcttcag
    15421 tgatttcttt tgctttttct tgtttcttag cttcgtccat agcatcgcga cggatattgc
    15481 ggacagccac tttagcattt tcgccgacct tcttcacttc tttagcaagg tcacgacgag
    15541 tttcttctgt aagagctggg ataaccaagc gaatcacaga accgtcatta gccggtgtga
    15601 taccaagatc agaagcgttc aaggcacgtt cgatgtcttt caatgaagac ttgtcaaatg
    15661 gtgttaccaa caaaacacgc gcttctggaa tcgtaattga agcgatttgg ttaagaggag
    15721 tttcgactcc atagtattct acatgtacac ggtcaagcaa gcttgcattg gcacgaccag
    15781 cacggatacc accaaattca cgagcaagtg attggtgaga ttgggtcatt ctctctttag
    15841 ctttttcaat aattacgtta gccatattct ttcttattcc ttttcttcga tattatttga
    15901 aactgttgtt ccgatatttt caccaaatac gacacgtttg atgttgcctg attggttcat
    15961 gttgaagaca accaagtcaa tgtcgttgtc cattgagagg gttgaggctg ttgagtccat
    16021 gatacgaaga cctttgttga taacatcacg gtgggtcaat tcttcaaact taacggctgt
    16081 cttgtccttc ttaggatcgg cattgtacac accatcgacg ccatttttag ccatgaggat
    16141 ggcatctgct tcgatttcag ctgcacgaag ggccgctgtt gtatctgtcg agaagtatgg
    16201 tgaaccaatt ccagcaccaa agataacgat acggcctttt tcaaggtgac gaagggcacg
    16261 tccacggaca taaggctctg ccacttgttg catagcaata gctgtttgta cacgcgtatc
    16321 aaccccaact tgttgcaatg aatctgccat cacaagagca ttcataacag tcccaagcat
    16381 tccagtgtaa tctgcctgaa cacggtccat acctgcttct gctgcaggtt ctccacgcca
    16441 aagatttcct ccaccaataa caagggcaat ttcgatacct aagctatgaa cttcttgaat
    16501 ctcttttgcg attgtttgaa ctgtttggat atcaatccct acgccacgtt caccggcaag
    16561 ggcttcacct gataacttga ttaaaatacg tttatacttg ggattcgcca ttttcactct
    16621 ccttctttca tcctacctat tttatcacaa tttctaagat ttttatagta tcatgagcaa
    16681 ttctttcaaa aaaattagac agtcaaaaat tcctctaagt cggcaagggc acgctctgca
    16741 attttttcat aacgagcctt cttatcacgg atacgctcgc cttccaactc cttgatgatc
    16801 ccaaaattga cattcattgg ttggaaatgt ttgctgtcgg catgggtaat gtaatgagct
    16861 aagcttccaa tcgctgtcgt ctcggggaaa ataacctcgc tttcttcctt gaagagacga
    16921 gctgcgttaa ttcccgcaac taagcccgaa gccgccgact caacatagcc ttccaccccc
    16981 gtcatctgac cagcaaagaa gagatttggt tgtttcttgg aacggtaagt ctgctcaaga
    17041 agatttggtg aatccatgta agaattgcga tgcatgacac cataacggac aaactccgca
    17101 ttttcaagac ccggaatcat ttggaagaca cgcttttgtt ctccccattt gaggtgggtc
    17161 tggaaaccaa caatattgta taggctacca gctgcattat cctgacggag ctggacaacc
    17221 gcataaggtg ttttaaattc tccatcacga ggtcctgtgt agtcgtccgg atactcaaga
    17281 ccaactggtt tcataggacc ataaagcatg gttttaatgc cacgtttggc catgacttcg
    17341 ataggcatac atccttcaaa gtacttttct ttttcaaaag aattaagcgg tgcttcttct
    17401 gcattgacca aagcttcatg gaaatccata aattcttgct tggtcatagg ggcattgagg
    17461 taggccgctt ctcccttatc ataacgtgat ttgaggtaga ccttgctcat atcgatagtg
    17521 ttgacatcga taataggcgc tgccgcatcg tagaaataaa aaccatcacc gtcattaagg
    17581 gcatgaatct tttcagccaa ggcatcactt gtcaaaggac cagtagcgat aaccgtaata
    17641 acatctgtcg gcaattctgt aatttcatca cgaaccactt caatcaaggg gtggttggca
    17701 actttttcgg tcaccatttg agagaaacca tcacggtcca ctgcaagggc accacctgca
    17761 ggaacacgtg tagcctcagc agattccaaa atcacagaac ccaagcgacg catttcttcc
    17821 ttaaggaggc caacagcatt tgtcaaagca tctccacgca aggaattgga acaaaccaac
    17881 tcagcaaaat tgtctgtttt gtgctgaggt gttgacttga caccacgcat ttcataaagt
    17941 ttaactggaa taccacgctc tgcgatttgg taggctgctt cagaacctgc caaaccagca
    18001 ccgataacat tgatataaga ttgagacacg acactaatac ctctttggga gtatgaagtt
    18061 aagattcaca ttgaaaaagc caatcagact tacgagcttt cgagtttctt ggctcaggct
    18121 gaaaaagtcc acaggacttt ttcactccca caaatctttc tatttttttc ttctactagt
    18181 ataacaaaaa aagggaagaa ggcaaacttc cctgtttagt cattttcttg atgtaaagag
    18241 ataaagagta ttccagttaa gaatcaatta tatgctactc tataaaatct tttccacata
    18301 acggatcgat agggactgtt attctatctc ttgctataac cgtattatct aaaacagcat
    18361 aacattcaac atagtgatct cctttaaact gtgaatcttc gtgatatttt attttacctg
    18421 aaaaaatagc accacgctca caatttcttc taatagcctc agcttcaata tttcttactt
    18481 tccaatagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaatg atgaagcaag
    18541 taaacaacta actgatgcac gatttaagcg tcttgttggt gttcagcgca cgacttttga
    18601 agagatatta gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa
    18661 acctaaatta agcctagaag acct
//
LOCUS       DBERCW010000037        17713 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.037, whole genome shotgun sequence.
ACCESSION   DBERCW010000037 DBERCW010000000
VERSION     DBERCW010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.037"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..502
                     /locus_tag="ACL72M_001668"
                     /pseudo
     CDS             1..502
                     /locus_tag="ACL72M_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            518..1015
                     /locus_tag="ACL72M_001669"
                     /pseudo
     CDS             518..1015
                     /locus_tag="ACL72M_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            1172..1597
                     /gene="lacA"
                     /locus_tag="ACL72M_001670"
     CDS             1172..1597
                     /gene="lacA"
                     /locus_tag="ACL72M_001670"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGS0716766.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1628..2143
                     /gene="lacB"
                     /locus_tag="ACL72M_001671"
     CDS             1628..2143
                     /gene="lacB"
                     /locus_tag="ACL72M_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGS0716767.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            2154..3083
                     /locus_tag="ACL72M_001672"
     CDS             2154..3083
                     /locus_tag="ACL72M_001672"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGS0716768.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            3085..4065
                     /gene="lacD"
                     /locus_tag="ACL72M_001673"
     CDS             3085..4065
                     /gene="lacD"
                     /locus_tag="ACL72M_001673"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGS0716769.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4299..5135
                     /locus_tag="ACL72M_001674"
     CDS             4299..5135
                     /locus_tag="ACL72M_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGS0716770.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5171..5488
                     /locus_tag="ACL72M_001675"
     CDS             5171..5488
                     /locus_tag="ACL72M_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0716771.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     DAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5490..7184
                     /locus_tag="ACL72M_001676"
     CDS             5490..7184
                     /locus_tag="ACL72M_001676"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS0716772.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7399..8805
                     /gene="lacG"
                     /locus_tag="ACL72M_001677"
     CDS             7399..8805
                     /gene="lacG"
                     /locus_tag="ACL72M_001677"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS0716773.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8928..9107
                     /locus_tag="ACL72M_001678"
     CDS             8928..9107
                     /locus_tag="ACL72M_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGS0716774.1"
                     /translation="MTSEELKSLGKWYVSTGKEWICHSDDELEEFKNLFLNFINPEEW
                     DTISFDSDFMPFQQS"
     gene            complement(9386..10147)
                     /locus_tag="ACL72M_001679"
     CDS             complement(9386..10147)
                     /locus_tag="ACL72M_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0716775.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10435..11397)
                     /gene="nrdF"
                     /locus_tag="ACL72M_001680"
     CDS             complement(10435..11397)
                     /gene="nrdF"
                     /locus_tag="ACL72M_001680"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGS0716776.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11585..13744)
                     /gene="nrdE"
                     /locus_tag="ACL72M_001681"
     CDS             complement(11585..13744)
                     /gene="nrdE"
                     /locus_tag="ACL72M_001681"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGS0716777.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13825..14043)
                     /gene="nrdH"
                     /locus_tag="ACL72M_001682"
     CDS             complement(13825..14043)
                     /gene="nrdH"
                     /locus_tag="ACL72M_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGS0716778.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            14394..14657
                     /locus_tag="ACL72M_001683"
     CDS             14394..14657
                     /locus_tag="ACL72M_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGS0716779.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14663..16396
                     /gene="ptsP"
                     /locus_tag="ACL72M_001684"
     CDS             14663..16396
                     /gene="ptsP"
                     /locus_tag="ACL72M_001684"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGS0716780.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16651..>17713
                     /gene="phtA"
                     /locus_tag="ACL72M_001685"
     CDS             16651..>17713
                     /gene="phtA"
                     /locus_tag="ACL72M_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGS0716781.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLR"
BASE COUNT         5606 a         3147 c         3660 g         5300 t
ORIGIN      
        1 caagaactcc tctcagctct gaggacacgg taatgattga tgcgacggaa gtacaaatca
       61 atcgccctaa aaaagaatta gcgaatgatt ctggtaaaaa gaaatgccac gctatgaagg
      121 ctcaagcgat tgtcacaagt caagggagat tgtttctttg gatatcactg tgaactattg
      181 tcatgatatg aagttgttca aaatgagtcg cagaaatatc ggacaagctg gtaaaatctt
      241 ggctgacagt ggttatcaag ggctcatgaa gatatatcct caagtacaaa ctccacgtaa
      301 atccagcaaa ctcaagccgc taacagttga agataaaacc tataaccatg cgctatctaa
      361 ggagagaagc aaggttgaga acatctttgc caaagtaaaa acgtttaaaa tgatttcaac
      421 aacctatcga aatcatcgta aacgcttcgg attacgaatg aatttgattg ctggcattat
      481 caatcatgaa ctaggattct agttttgcag gaagtctaat aaagaaacta gcaaggtcag
      541 gccttacttt attggtggac atccaggatt taattgtcct ctacttgatg atgaagtcta
      601 tgaagattat tatctagagt ttgagaaaga agagacttgc tctgttccac gtcctttccc
      661 agaaacaggt atgttggatt tccaagatag aagtccatgg ctagagggac aaaaagaaat
      721 agatcttagt tatgatcttt tcagcaaaga tgcagtgact ttggatgaat tgcaatctcg
      781 aacaattgcc cttcgttctc ttaaacatga taggggattg aaagtgcatt ttgcagaatt
      841 tccaaacctc atcatctggt caactttgaa caagggacct ttcattacct ttgaaccatg
      901 gtctggcttg tcaacattcc ttgaagaagg agatcattta gaagataaga agaatgtttg
      961 tctcttagaa gccaatcagg ttgaagaatt agggtttgag atagaagttt tataaaaaag
     1021 taaaaaataa ataacaaaaa caaacacaaa ctgttgactt cttcaaacaa tagtagtata
     1081 ttatgtttgt gaggactaat tgactgtttt ttaaagacag ccaatacact gctggaatcc
     1141 agcatagaaa aaataaaaag gagtatacaa tatgtctatt gttatcggtg cagatgctgc
     1201 aggtttgaga ttgaaagaag ttgtgaaaga cttcttagaa aaagaaaact tccaccttgt
     1261 ggatgttaca gctgaaggtc aagactttgt tgatgtgact ctcgctgttg ctgcagaagt
     1321 aaacaaagaa gaacaaaacc ttggtatcgt gattgatgct tatggagctg gtccatttat
     1381 ggttgcaact aagatcaaag gaatggttgc tgcagaagtt tctgatgaac gttcagctta
     1441 tatgactcgt ggccacaaca actcacgtat gatcactatg ggtgcacaac ttgttggtga
     1501 tgaattggct aaaaacatcg ctaaaggatt tgttaatggt aaatacgacg gtggtcgtca
     1561 ccaaatccgg gttgacatgt tgaacaaaat gggctaatta gattatagta agaaaggtaa
     1621 gttaaaaatg agaattgcaa ttggatgtga ccacatcgta acagatgaaa aaatggcggt
     1681 ttcagaattt ttgaaatcaa aaggatatga agtcattgac tttggtacat atgaccatac
     1741 acgtactcac tacccaatct ttggtaaaaa agtaggggaa gctgtaacta gcggtcaagc
     1801 tgatcttgga gtatgtatct gtggtactgg tgttggtatc aacaacgctg taaataaagt
     1861 tccaggtgtt cgttctgcct tggttcgtga tatgacaaca gccctttatg ctaaagaaca
     1921 attgaacgct aacgttattg gttttggtgg taaaattact ggtgaattgc ttatgtgtga
     1981 tatcatcgaa gctttcatcc atgctgaata caaaccaact gaagaaaaca aaaaattgat
     2041 tgcgaaaatt gaacatgttg aaagtcacaa tgctcaacaa acagacgcaa acttcttcac
     2101 tgaattcctt gaaaaatggg atcgcggaga ataccacgac taagaggtaa cctatgattt
     2161 taacagttac aatgaaccca tccattgata tttcctatcc cttggatgag ttgaagattg
     2221 atactgtcaa tcgtgtggtg gatgtaacca aaacggctgg tggtaaggga ctcaatgtta
     2281 cccgagtact ttcagaattt ggcgattctg ttcttgctac tggtttagtg ggtggcaaac
     2341 ttggtgagtt tttggttgaa catatcgata atcaagtaaa gaaagatttc ttctcaattc
     2401 agggagaaac tcgtaactgt atcgctattc tccacggaga caaccaaaca gaagttcttg
     2461 aaaaaggtcc tgaagtattg gaacaggaag gtcaagactt tttggaacat ttcaaaaaac
     2521 tcttggagtc agttgaagta gtggccatct caggtagtct gccagctggc cttccagttg
     2581 attactatgc gagcttggta gaacttgcta atcaagctgg caagcctgta gtcttggact
     2641 gctcaggtgc agcacttcag gctgttcttg aatcacccca taaaccaaca gtcatcaaac
     2701 caaataatga agaattgtct cagcttcttg gaagagaagt ttctgaggat ttggatgaat
     2761 taaaagaagt acttcaagaa cctttgtttg cagggattga atggattatc gtttcacttg
     2821 gtgccaacgg tacttttgcc aaacatggtg acactttcta caaggtagat attcctagaa
     2881 ttcaggtggt aaatcctgtt ggatctggag actctactgt ggcaggaatt tcttcaggac
     2941 ttcttcacaa agaatcggat gcagaattac tcatcaaggc aaatgtcctt ggtatgctca
     3001 atgctcaaga aaaaatgact ggtcatgtca acatggccaa ctatcaagtt ctatatgatc
     3061 aattaatagt aaaagaggta taaaatggct ttaacagaac aaaaacgtgt acgcttagaa
     3121 aaactttctg atgaaaatgg tatcatctca gctcttgcat ttgaccaacg tggtgctttg
     3181 aaacgcctca tggctcaaca ccaaacagaa gaaccaactg tggcccaaat ggaagaactt
     3241 aaagtcttgg tagcagatga attgactaaa tacgcttcat ctatgcttct tgaccctgag
     3301 tatggacttc cagcaactaa agctcttgat gaaaaagctg gtcttctcct tgcttatgaa
     3361 aaaacaggtt atgacacaac aagcacaaaa cgcttgccag actgcttgga tgtctggtct
     3421 gcaaaacgta ttaaagaaga aggtgcagat gcagttaaat tcttgcttta ctatgatgta
     3481 gatagctcag acgaactcaa tcaagaaaaa caagcctaca tcgaacgcat cggttctgag
     3541 tgtgtggctg aagatatccc attcttcctt gaaattcttg cttacgatga aaaaattgcg
     3601 gatgcaggtt ctgtagaata cgcgaaagta aaaccacaca aagttatcgg cgctatgaaa
     3661 gtcttttcag acccacgctt taacattgat gtcttgaaag ttgaagttcc tgttaacatt
     3721 aaatatgttg aaggcttcgc tgaaggtgaa gtagtttata cacgtgaaga agcagcagcc
     3781 ttcttcaaag cgcaagatga agcaacgaac ttgccataca tctacttgag tgctggtgta
     3841 tcagctaaac tcttccaaga tactcttgta tttgctcatg aatcaggtgc aaactttaac
     3901 ggagttcttt gtggccgtgc aacatgggct ggatcagttg aagcatacat caaagatggt
     3961 gaaacagcag ctcgcgaatg gcttcgcaca actggatttg aaaacattga tgagctcaac
     4021 aaagttcttc aaacaacagc aacttcatgg aaagaacgtg tgtaagaaag tcctcctagt
     4081 ttaggaacat gaatctaaaa aaatttaaaa aaagttgtat gtaaaggttt acaaaataac
     4141 ttacttgtgc tatacttaaa tcacaagtta atacaaggtg agtgttacta agtaatatta
     4201 ggcatgatca caggtgaatt agaaatcagc tgattttcta gttcatttgt ggtcattttt
     4261 tgtactcata tacctttaag atataaaagg aggttgacat gtatcgaatt ctaaatccaa
     4321 tgaatcacaa tgtctcgctt gtcagaaatg ataagggaga agaggtgatt gtaattggta
     4381 aggggattgc attcggaaag aagaaggggg atttgattgc tgaaaatcat gttgagaaaa
     4441 tctttcggat gaagaccgaa gagtccagag aaaactttat ggctcttctc aaagatgttc
     4501 cgcttgattt tatcacagtg acctatgaaa tcattgataa gctatcaaag aaatatcatt
     4561 atccgattca agagtatctc tatgtaacct tgacagatca tatttactgt tcttatcaag
     4621 ctctaactca aggaaggtac aaggatagta atctgccaga tatttctgct aagtatcctg
     4681 tcgcttttca aatcgcaaat gaagcttttg aaatttactg tcagaagcta gcagatcatt
     4741 ttcctgagga cgaaattatt cggattgctt atcatttcat taatgctgaa ggtgaaaatg
     4801 aagtggaact tgtggagtcg attgataaga ggaaagaaat tctcaggaat gttgaagaag
     4861 ttttaacgga ctatgcaatt caacgaacta aaaagaataa ccatttctat gatcgcttta
     4921 tgatccattt gaattatttc ttggattatt tagacagatc tagagatgat aaccaatcac
     4981 ttctggatat ggaagatcat attaaacaat cctatccaaa agccttcgag attggttcca
     5041 agatctatga tgtgattacg caacatacgg gtcttgattt gtataaaagt gaacgagttt
     5101 atctagttct acatatccaa cgtttattgt cataaaaatt tatttaaaac tatataagga
     5161 gaattctatc atgaatagag aagaagtaac attgttaggt tttgaaatcg tagcctatgc
     5221 tggcgatgct cgttcaaaac tattggaagc cttgaaggct gctgaagctg gtgattttga
     5281 aaaagcggac gctctggtag aggacgctgg tagctgtatt gcagaggctc accacgcgca
     5341 aacaagtcta ttgactaagg aagcttctgg tgaggactta gcgtatagtg tgaccatgat
     5401 gcatggtcaa gatcacttga tgacaactat cttgttaaaa gacctaatgc accatttaat
     5461 tgaactttac aagagaggag ttaaataaaa tggataagtt aataattttt attgagaaag
     5521 gaaagccttt ctttgagaaa ttatcgagaa atatatactt aagagcgata aaagatggtt
     5581 ttatttccag tatgccagca gtattattct caagtatttt tatactaata gctgctgtgc
     5641 ccaatatttt tgggtttaaa tggtctgatg aacagttagc ttttattttg aaaccttaca
     5701 actactcaat ggggatttta gctctcttag tagctgggac aactgcaaaa tcgttaacag
     5761 attcagttaa tacacgtagt atggagaaaa ccaaccaaat caactacatg tcaacttttt
     5821 tagcagctgt tgttggattg ttaatactgg cagctgatcc aattgaaggt ggatttgcta
     5881 atggtctttt aggtactaga ggattactta ctgcattttt ggcagctttt attacagtaa
     5941 atatctataa agtatgtatt aaaaataatg taaccattag acttcctgaa gaggttccac
     6001 caaatattgc acaagttttt aaagatgtta ttccgtttgc cttatctgtt ctttcaatat
     6061 atggattgga tttaattgtt agaaatattt ttggtacaaa tgtagcagaa tctgttggta
     6121 aaatattagc ccctctattt tcagctactg atggttatat cggtttagct attgtatttg
     6181 gtgcttatgc tttcttttgg tttgttggaa ttcatgggcc atctgttgta gaacctttaa
     6241 ttgtagctat cagttatgca aatatagaag ctaatgttca gcttgtgcaa gctggtatgc
     6301 acgcagataa aattttaaat ccagttactc aaacttttgt tgtaacaatg ggtggtactg
     6361 gtgcaacact agtagttcca tttatgttta tgtggttatg taaatcaaaa agaaatagaa
     6421 ttgtcggacg tgcgtctgta gttcctactt tctttggcgt aaatgaacca atcctatttg
     6481 gtgctccaat tgttttaaat cctatcttct ttattccgtt tgttactgct cctattatca
     6541 atgtttggat tatgaaattt tttgtagatg ttctacaaat gaatagtttc agtattattt
     6601 taccttggac aacacctgct ccaattggta ttgttatggg aacggcgctg gctccattgt
     6661 cattcgtctt ggctataact ttaatcatta tcgacacttt aatctattat ccatttgtta
     6721 aagtttatga ccatcaaatt ttagaagaag aacggaaagg aaactcttca tctgaattga
     6781 aagaaaaagt tgctgcaaac ttcaacactg caaaagcgga tgctattctt gaaaaagcag
     6841 gtgtcgatgc agcacaaaat accatcactg aagaaacaaa tgtcctcgtt ctctgtgctg
     6901 gtggaggtac aagtggactc cttgcaaatg ctttgaataa ggcagcagca gaatacaatg
     6961 tccctgtgaa agcagcagca ggcggctatg gtgctcaccg tgaaatgtta ccagagtttg
     7021 atttggttat ccttgctcct caagttgctt caaactttga agatatgaag gcagaaacag
     7081 ataagctcgg tattaaacta gcgaaaacag aaggcgctca atacatcaaa ttaactcgtg
     7141 atggaaaagg tgccctagca ttcgtacaag aacaattcga ttaaggctag gaactgtgaa
     7201 acagtctcct atcgttacgg aaatcgctat ggcgaatttc ctaatcgcct tattaattcg
     7261 tcggtaaaaa gatatcgttt ttacctcctc atgtcacaat tcggtgactt ggtacaagaa
     7321 gtgagatgga gaaggatggc tcactgactc ctctcctctc acttttactt tatttaaatc
     7381 aagaaatagg tgaaaaaaat gacaaaaaca cttccaaaag actttatttt tggtggcgca
     7441 acagctgcct atcaagcaga aggtgctaca catactgatg gtaaaggacc agtagcgtgg
     7501 gataaatatc ttgaagataa ctactggtac actgcagaac cagccagtga tttttacaat
     7561 cgatatccag ttgatctcaa gctagcagaa gagtatggtg tcaatggcat tcgaatttct
     7621 attgcctggt cacgtatttt cccgactggt tatggtcaag taaatgctaa aggtgttgag
     7681 ttttatcata atttatttgc agagtgtcac aaacgtcatg ttgagccctt tgtaactctt
     7741 catcactttg acacgccaga agctctccac tcaaatggag acttcttaaa ccgtgaaaat
     7801 atcgaacatt ttgtagacta cgctgccttc tgttttgaag aatttccaga agtaaactat
     7861 tggacaacct tcaatgaaat tggaccaatc ggtgatggtc aatatttggt tgggaaattc
     7921 cctccaggta tccagtacga ccttgccaaa gtctttcaat cacaccacaa tatgatggtg
     7981 tctcatgcat gcgcggtaaa attgtacaaa gagaaaggct ataaagggga aattggtgtt
     8041 gttcacgccc tgcctactaa atatcctcta gatcctgaaa atccagcaga tgttcgtgca
     8101 gcagagttgg aagatatcat ccacaataaa ttcatcttag acgcaactta tctaggtcgc
     8161 tattcagctg aaaccatgga aggtgtcaac catatcttat cagtcaatgg tggtagtttg
     8221 gatcttcgtg aagaagattt tacagcatta gaagctgcaa aagacttgaa tgatttccta
     8281 ggaatcaact actatatgag tgactggatg gaagcctttg atggagaaac tgaaattatc
     8341 cataatggta aaggtgaaaa aggaagctct aagtatcaaa tcaaaggtat tggtcgtcgt
     8401 gtagctcctg actatgtatc acgcacggat tgggattgga ttatctaccc tcaaggtttg
     8461 tatgaccaaa tcatgcgtgt gaagaaagat tatcctaact acaagaagat ttacatcact
     8521 gaaaatggtc tcggctataa agatgagttc gttgataaca ctgtttacga tgatggtcgt
     8581 attgattacg tgaaacaaca cttggagatc ttgtctgatg cgattgcaga tggagctaat
     8641 gtaaaaggtt acttcatttg gtcattaatg gatgtcttct catggtcaaa cggttatgag
     8701 aaacgttatg gtctcttcta cgtagatttt gaaactcaag aacgttatcc taagaaatca
     8761 gctcactggt acaagaaagt agcggaaact cagattatag actagtagaa ttagtcatta
     8821 gatatagaat tttagtgagt caaaaagatg ttcaaagatt ttatccaatc tatttatgaa
     8881 aaaaagttta tattataaat ttcgaaaaat gctctcaaat accgtgtttg acgagtgaag
     8941 aattgaaaag tcttggaaaa tggtatgtct cgactggtaa agaatggatt tgtcattcag
     9001 atgatgagct ggaagaattt aaaaatctat ttttaaattt tatcaatcct gaagaatggg
     9061 atactatctc ctttgattca gattttatgc cgtttcaaca atcgtaacca atttctcaaa
     9121 aaagttaaat cttatattta gtactctgta aaactcttat ctaatcacgt tgcttatact
     9181 caatgaaaat caaagagcaa ctttaaacta ggaagcgagt cgcagatttc tcaatgcata
     9241 gctttgagga attgggcaaa aagtctttga tatagaaaaa agcatagtat caggtgttga
     9301 aacacctgat actatgcttt ttattgtggg aagatttact ttttttcttc tgaaattgag
     9361 ttgttaccca ggctctttca gtttattaag gcttgatgac tttaatgtgt ttagatagct
     9421 taaaaaggat tgaatcactt agtttagaat ctgaaacaat agtatcaaga tttgatatat
     9481 tataaaaagt ataaaaatca aacttattga acttactatg atctgcgagt aaatattttt
     9541 tattagaatt atttaaagcg atgcgttgag cctctccctc ttcctcgcta aaagtagcta
     9601 gagctccgtt ttgaatacca ttacagctaa cgaaagcttt agaaaattgg agattagaga
     9661 gattttgtag ggtcaatgtg ccaacaaaag cacctgtaat atcgcgataa tttccaccta
     9721 tcaaaatcaa atctgttaat tttcgttcgc ttaaaatcag aaaaacaggt agactgttgg
     9781 ttacgacgcg gatattgtca ataggcaact cacgcgcaaa aaactctaat gttgttcctg
     9841 gtccaatgaa aatagtttct ctttcttcta ctagactgcc tgcaaaatgg gctatttctt
     9901 gtttttctgc cgtttggagg gcttgttttt caatatttga tcgctcatta gtcaaaaggg
     9961 agttggttcg aagtttttca gctccaccat gcacacgaat cagcaaatct ttatcagcta
    10021 attcctgtaa atagcgcctt gcagtcatat ctgaaacggc tatttcgtcc ataatctgtt
    10081 taactgttat ggttccttta ctatttacta tctctaaaat tttggttaat ttttcttgtt
    10141 tgagcatatt atcacctcgt ttcctactac tatcttacca taaacaaact catcattcaa
    10201 atacaaaaac aacaaaatga aacaaaaaca aaaatatcga agtttgtttt caaaactttc
    10261 gatatttttg ttgggttatt attttgttgt ttctagttta ctttttgatg gttaagagtg
    10321 gtggagaatt atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggctgta
    10381 cttgagtacg gcaaggcgaa gctgacgtgg tttgaatttg attttcgaag agtattagtc
    10441 caaaccgtag ttgtagtcat catcttgcat ggcttcaact tcgccaagaa ggtaaccatt
    10501 tccgacttga gagaagaagt catggttgga agttcctgtt gaaataccgt tcataacgat
    10561 tgggttgaca tcttcagctg aatctgggaa aagtggatct tgtcccatgt tcatgagagc
    10621 tttattggca ttgtagcgaa ggaaggtttt aacctcttca gtccaaccaa caccgtcata
    10681 aagactctct gtgtagcctt cttcattttc ataaagagta tagagtaggt cgtacatcca
    10741 ttctttgagt ttttcttgct cttcttcagg taattcattg aaaccaagtt ggaatttgta
    10801 accaatgtag gttccgtgaa cagactcgtc acgaataatc aatttaatga tttctgcaac
    10861 gttggcaagt ttgttgttac cgagatagta gaggggagtg aagaaaccag agtagaagag
    10921 gaaggtttcg aggaagacgc tggcaacttt cttttcaagt gggctgccgt ttaggtagat
    10981 ttcgttgaca atctcagcct tcttttgtag gtaaggattg gtattggtcc attcgaaaat
    11041 ttcttcaatc tcagccttag tattcaaggt agaaaagatt gatgagtaag atttagcgtg
    11101 gacagattcc ataaattgga tgttattgaa aacagcttcc tcatgtggtg tacggatgtc
    11161 tgcgcgaagg gcttgaaccc cagtttcaga ttgcatagtg tcaagaaggg ttaaaccacc
    11221 aaaaactttt ccgaccaagt ctttctcttt gttagatagc tttctccagt catccaagtc
    11281 gtttgataag ggaatacgtg tatcgagcca aaattgctcc gtcagttttt cccaagttga
    11341 tttgtcgatg acatcttcga tggcattcca gttaatggct ttgtagtaag tttccattta
    11401 aaatctcttt ctgtgtttag tattgcgaac tcacaattat ttctacttta ccataattct
    11461 ataggagtat cgcacaaaaa gtcggaagcc cgacttttaa aatgttacat aaattatgtt
    11521 atgacatagt agatttgatt ttatcagtgc tgcttaggga aaaatagtgt ttctatgcta
    11581 gaaactaaat cacacagctt tcacattggt tggcgccgac ttctccaccg tcatctgtaa
    11641 aggtacggac gtagtagata gacttgattc ccttgttaaa ggcatagtta cgaaggatgg
    11701 acaagtcacg tgtcgtttgt ttattttccc tcttccattc gtaaaggcct tttggaatgt
    11761 cactacgcat gaagagggtg agtgaaagtc cttgatccac gtgttcagtc gcagcagcgt
    11821 aaacatcgat gactttacgc atatccatat cgtaggcaga agtgtagtaa ggaatggttt
    11881 ctgtagacaa gccagcagca gggtagtaga ttttaccaat tttcttttcc tgacgttctt
    11941 caatacgttg cgtaatcggg tggatagaag cagaaacatc gttgatgtag ctgatagaac
    12001 catttggcgc tacagcaagg cgattttggt ggtaaagacc atcctcttga accttgtcgc
    12061 gaagttcagt ccaatcagca acaccaggga taaaaacatt tttgaagagt tctttaacac
    12121 ggtctgatgt tggaacaaat tcaccagtta catacttgtc aaagtaactt ccgttagcat
    12181 agtctgattt ttcaaagttg tggaaggtaa taccacgttc acgcgcaata ttgtttgact
    12241 ctaccaaggt ccagtagttc ataagcataa agtagatgct tgtaaattca acagactcag
    12301 gtgaaccata ttcaatgagt tgttgggcaa ggtagctgtg cagtcccatg gcaccgagac
    12361 caaaggtgtg ggcttggcta tttccatggt caatcgttgg tacagctacg atatgtgaac
    12421 tatctgtaac gaaagtaagg gcacgaacca tagcacggat agaacgacca aaatcaggtg
    12481 aagtcatcat gttaaccacg ttggttgaac ccaggttaca tgaaacatct gttcccattt
    12541 gaaggaattc ttgagcatcg ttgatcaagc ttggttcttg aacttgaaga atctcagaac
    12601 acaagttact catgataatc tttccatcga caggatttgc acggttagcc gtatctatgt
    12661 tgactacata aggatagcca gactcttgtt gcaatttaga gatttcagtt tccaaatccc
    12721 gcgccttgat ttttgtcttg cgaatatttg gatttgcgac caattcatcg tatttttcag
    12781 taatgtcgat gtaattgaat ggcacaccgt attctttttc tacagagtaa gggctgaaga
    12841 ggtacatttc ttcattttta cgagccaatt cgtagaattt atcaggtact acaacaccaa
    12901 gtgatagagt cttgacacgt actttttcat cagcgttttc tttcttagtt gaaaggaaag
    12961 cgatgatatc tgggtgaaag acgttgaggt agacaacacc ggcaccttga cgttgcccca
    13021 attggttgga gtaagagaag ctgtcttcaa aaagcttcat aacaggaacg acacctgaag
    13081 cagctccttc atagcctttg ataggtgcac cagcttcacg aaggttgctg agggtaattc
    13141 ccacaccacc accaatacgt gaaagttgaa gagctgagtt gatagaacgt ccgatagagt
    13201 tcatatcatc cgtcacttgg attaggaaac aagataccaa ctccccacga cgagcacgtc
    13261 cagcattcaa gaaggaagga gtagcaggtt ggtagcgttg gtggatgatt tcattggcaa
    13321 tatcgattgc aacagcttca ttcccatcag cgaaataaag ggcgttgaag aagacacggt
    13381 cttccatatt ttcaagatag tattcaccgt cattagtctt taaggcatat tgattgtaaa
    13441 atttataagc tgccatgaat gacttgaatt ggaagttttg gtctttgata aattgagcca
    13501 attcttccaa gaactctgga cggtatttct tgataaaggc tgtttcgatg tagttgtgtt
    13561 caatgaggta attgattttg tctttgattg aatcaaaaac catagtgttt ggaactacat
    13621 tttctttaaa gaaagcatcc aaggcttcct tatctttatg aagcatgatt tgtccattaa
    13681 caggacggtt aatttcgtta ttaagacgga agtaagtcac gtcttcaaga tgttttaatc
    13741 ccataaaatt tcccttatct aattacaaaa gaaaggcttc taagttagcc ctaaaagcag
    13801 tttcttctgg atgatgtact aagattatgc taattgtttc agtttttctg gttggaaacc
    13861 tgaaaagact tcagttggtg tttggataac aggagctgcg ctaaaaccga gctctttaac
    13921 ttgatcgacg tactcaggtt gctcatcaag attgatttca cgataagaga cattattact
    13981 gtccaagaaa cgcttggtca ttttacattg gacacaattg tttttagaat aaacggttac
    14041 cattgtgtaa ctcctcttca aaatttaata ctatcttagt atatcagaaa ataaaatttt
    14101 gtcaatgatt taaactaaat atagtggtgt tcttttgttg tttttatata taaacacaat
    14161 atatagtgtt tgtattgtga aatagcaatg attatcctat aaattgtttt tgaagaaact
    14221 atatcctgtg ttttgttatc taggatagaa gattttcagc aagttatctg aaaggaaatt
    14281 gaaggaaaat ccagaaaatg cttgaaaaaa atcctagaag atggtataat actaaattgt
    14341 aagggttatc acatataact caaaaaaaga aagaacaaaa ggagagtcaa actatggctt
    14401 ctaaagattt ccacgtagtg gcagaaacag gtattcacgc acgtccagca acattgttgg
    14461 tacaaactgc tagcaaattt gcttcagata tcactcttga gtacaaaggt aaatcagtta
    14521 accttaaatc aattatgggt gttatgagtc ttggtgttgg tcaaggtgct gacgtaacta
    14581 tctcagctga aggtgcagat gcagatgacg ctatcgctgc aatctcagaa acaatggaaa
    14641 aagaaggatt ggcataaggg aaatgacaga aatgcttaaa ggaatcgcag catctgacgg
    14701 tgttgcagtt gcaaaagcat atctactcgt tcagccggat ttgtcatttg agactattac
    14761 agtcgaagat acaaacgcag aagaagctcg ccttgatgcc gctctacagg catcacaaga
    14821 cgagctttct gttattcgcg agaaagcagt aggtacgctc ggtgaagaag cagctcaagt
    14881 ttttgatgct cacttaatgg ttcttgctga cccagaaatg atcagccaaa tcaaggaaac
    14941 tatccgtgcg aagaaagtga atgcagaagc aggtctgaaa gaagttacag atatgtttat
    15001 cactatcttt gaaggcatgg aagacaaccc atacatgcaa gaacgcgcag cggatatccg
    15061 cgacgtgaca aaacgtgtat tggcaaacct tcttggtaaa aaattgccaa acccagcttc
    15121 tatcaatgaa gaagtgattg tgattgcgca tgacttgact ccttcagata cagctcaatt
    15181 ggacaaaaac tttgtaaaag cttttgtaac caacattggt ggacgtacaa gccactcagc
    15241 tatcatggca cgtacacttg aaattgctgc tgtattaggt acaaacaaca tcactgaaat
    15301 cgttaaagac ggtgacatcc ttgctgttaa cgggatcact ggagaagtga ttatcaaccc
    15361 gacagatgaa caagcggcag aatttaaagc agctggtgaa gcctatgcga aacaaaaagc
    15421 tgaatgggca cttttgaaag atgctcaaac agtgactgct gacggtaaac acttcgagtt
    15481 ggctgccaat attggtactc caaaagacgt tgaaggtgtt aacaacaacg gtgcagaagc
    15541 tgttggactt taccgtacag agttcttgta catggattct caagacttcc caactgaaga
    15601 tgagcagtat gaagcataca aggctgttct tgaaggaatg aacggtaaac ctgttgtcgt
    15661 tcgtacaatg gatatcggtg gagataagga acttccttac ttcgatatgc ctcacgaaat
    15721 gaacccattc cttggattcc gtgctcttcg tatctctatc tctgagactg gagatgctat
    15781 gttccgcaca caaatccgtg ctcttcttcg tgcgtctgtt cacggtcaat tgcgtatcat
    15841 gttcccaatg gttgcgctct tgaaagaatt ccgtgcagcg aaagcagtct ttgatgaaga
    15901 aaaagcaaac cttcttgctg aaggtgttgc agttgcggat aacatccaag ttggtatcat
    15961 gatcgagatt cctgcagcgg ctatgcttgc agaccaattt gctaaagaag ttgacttctt
    16021 ctcaattggt acaaacgact tgatccaata tacaatggca gcagaccgta tgaacgaaca
    16081 agtttcatac ctttaccaac catacaaccc atcaatccta cgcttgatta acaatgtgat
    16141 caaagcagct cacgctgaag gtaaatgggc tggtatgtgt ggtgagatgg ctggtgacca
    16201 acaagctgtt ccacttcttg tcggaatggg cttggatgag ttctctatgt cagcaacatc
    16261 tgtacttcgt acacgcagct tgatgaagaa actcgacaca gctaagatgg aagagtacgc
    16321 aaaccgtgcc cttacagaat gctcaacaat ggaagaagtt cttgaacttc aaaaagaata
    16381 cgttaatttt gattaatcga aaagtccctg caactcagtt acagggactt tttttgatat
    16441 tttaaaaaga attttcaaga aaatctttct tataaaaagt ccaaccttga aaaagtagtg
    16501 gtcagaacaa aaaatactta aatggttcat aaaattcttg acaagttgga gatttaggag
    16561 taaactatta accagttaag taatagagag gagtttctgc aatttagaaa tgaattgcaa
    16621 ctagaaatat caaatagaaa gagagtttcg atgaaaatta ataagaaata ccttgttggt
    16681 tctgcggcag ctttgatttt aagtgtttgt tcttacgagt tgggactgta tcaagctaga
    16741 acggttaagg aaaataatcg tgtttcctat atagatggaa aacaagcgac gcaaaaaacg
    16801 gagaatttga ctcctgatga ggttagcaag cgtgaaggaa tcaatgccga acaaatcgtc
    16861 atcaagataa cagaccaagg ctatgtcact tcacatgggg accactatca ttattacaat
    16921 ggtaaggttc cttatgacgc tatcatcagt gaagaattgc tgatgaagga tccaaactac
    16981 cagctaaagg acgaggatat tatcagtgaa atcaagggtg gttatgtgat taaggtagat
    17041 ggaaaatact atgtttacct taaggatgca gctcatgcgg ataatgtccg tacaaaagaa
    17101 gaaatcaatc ggcaaaaaca agaacatagt cagcatcgtg aaggagggac ttcaacaaac
    17161 gatggtgcgg tagcctttgc acgttcacaa ggacgctata ctacagatga tggttatatc
    17221 tttaatgctt ctgatatcat tgaggacacg ggtgatgctt atatcgttcc tcacggcgac
    17281 cattaccatt acattcctaa gaatgagtta tcagctagcg agttagctgc tgcagaagcc
    17341 ttcctatctg gtcggggaaa tctgtcaaat tcaagaacct atcgccgaca aaatagcgat
    17401 aacacttcaa gaacaaactg gctaccttct gtaagcaatc caggaactac aaatactaac
    17461 acaagcaaca acagcaacac taacagtcaa gcaagtcaaa gtaatgacat tgatagtctc
    17521 ttgaaacagc tctacaaact gcctttgagt caacgccatg tagaatctga tggccttgtt
    17581 ttcgacccag cgcaaatcac aagtcgaacc gccagaggtg tagctgtccc tcatggtaac
    17641 cattaccact ttatccctta tgaacaaatg tctgaattgg aaaaacgaat tgctcgtatt
    17701 attccccttc gtt
//
LOCUS       DBERCW010000038        17371 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.038, whole genome shotgun sequence.
ACCESSION   DBERCW010000038 DBERCW010000000
VERSION     DBERCW010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17371
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.038"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            627..1079
                     /locus_tag="ACL72M_001686"
     CDS             627..1079
                     /locus_tag="ACL72M_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS0716782.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKAGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1098..2435
                     /locus_tag="ACL72M_001687"
     CDS             1098..2435
                     /locus_tag="ACL72M_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0716783.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2514..3398
                     /locus_tag="ACL72M_001688"
     CDS             2514..3398
                     /locus_tag="ACL72M_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0716784.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWIINGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3398..4231
                     /locus_tag="ACL72M_001689"
     CDS             3398..4231
                     /locus_tag="ACL72M_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0716785.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4249..6342
                     /gene="nanB"
                     /locus_tag="ACL72M_001690"
     CDS             4249..6342
                     /gene="nanB"
                     /locus_tag="ACL72M_001690"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGS0716786.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6354..7457
                     /locus_tag="ACL72M_001691"
     CDS             6354..7457
                     /locus_tag="ACL72M_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS0716787.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7631..8329
                     /locus_tag="ACL72M_001692"
     CDS             7631..8329
                     /locus_tag="ACL72M_001692"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS0716788.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8348..9865
                     /locus_tag="ACL72M_001693"
     CDS             8348..9865
                     /locus_tag="ACL72M_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS0716789.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALAVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9990..11318
                     /locus_tag="ACL72M_001694"
     CDS             9990..11318
                     /locus_tag="ACL72M_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0716790.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11570..12436
                     /locus_tag="ACL72M_001695"
     CDS             11570..12436
                     /locus_tag="ACL72M_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0716791.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAIMIAIVSF
                     VQFKVLGNDVEY"
     gene            12452..13291
                     /locus_tag="ACL72M_001696"
     CDS             12452..13291
                     /locus_tag="ACL72M_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0716792.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13563..14015
                     /locus_tag="ACL72M_001697"
     CDS             13563..14015
                     /locus_tag="ACL72M_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS0716793.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14112..14456
                     /locus_tag="ACL72M_001698"
     CDS             14112..14456
                     /locus_tag="ACL72M_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716794.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14466..14660
                     /locus_tag="ACL72M_001699"
     CDS             14466..14660
                     /locus_tag="ACL72M_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716795.1"
                     /translation="MKALCIFLLYMLAWTVLAMIIRGGLDGFDEHTWRTILIASLSGI
                     YIDYMSIDKSRKKSKRKKKK"
     gene            14743..15387
                     /locus_tag="ACL72M_001700"
     CDS             14743..15387
                     /locus_tag="ACL72M_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS0716796.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15556..16473
                     /locus_tag="ACL72M_001701"
     CDS             15556..16473
                     /locus_tag="ACL72M_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGS0716797.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTSSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEDDRPVVEAAAALIRETKERFL"
     gene            16491..>17371
                     /locus_tag="ACL72M_001702"
     CDS             16491..>17371
                     /locus_tag="ACL72M_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS0716798.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
BASE COUNT         5518 a         2922 c         3625 g         5306 t
ORIGIN      
        1 actaaattcc aaattagaaa aagacttgaa atactaaaaa aaaaagcata ctctaattga
       61 aaacggtaac aaaactaatt tagagaatga aatatagagt atttctctct taaaagtttt
      121 tggtgaaacg agatgtagaa aggagattta gccaaagagt ctattagtgc tagaataata
      181 gattagaatt attttagaaa aacgaagtga gcagcttata aattcaagtc cccaaataga
      241 ttcatactag tatcttttgc aaaaaataaa gggcgacttc cttcatgaat atcaatttca
      301 tctataagga aggtagctaa ttgaactaac ttatttattc tgtttgtcgc tagaaaaatc
      361 agacctcctt gtgaagattg aggagatact taatgaaaat caaagaagaa actagcaagc
      421 tagtagcaga ttgcccaaaa caccgctttg aggttgtaga taagactgac gtatataatc
      481 caaggtgaag cgactgtggt ttgaagagat tttcaaagag tataggctag agagtagtgt
      541 ttttatgtcc ttctagtaga aaatgctaga cagaagaatg gggaacttgg ataggagaaa
      601 tagattgaga aaggaggtta gaagagatga ttattacaaa aattagccgt ttaggaactt
      661 atgtgggagt aaatccacat tttgcaacat taatagattt tctagaaaaa gcaggactag
      721 aaaatttaac agaaggttcg attgctatcg atggtaatcg attgtttggg aattgcttta
      781 cttatctagc agatggtcaa gcaggggctt tctttgaaac acaccaaaaa tatttggata
      841 ttcatttagt tttggaaaac gaagaagcca tggctgttac atcgccggaa aatgtaagcg
      901 ttacccaaga atatgatgaa gagaaagata ttgaattata cacagggaaa gtggaacagt
      961 tggttcagtt gagagctggc gaatgcctca tcacttttcc agaagattta catcaaccca
     1021 aggttcgtat aaatgatgaa cctgtgaaaa aagttgtctt taaagttgcg atttcttaat
     1081 gtagaaagag aagaacgatg aaaaaaatga gaaagttttt atgtctagct ggaattgcgc
     1141 tagcggctgt tgccttggta gcttgttcag gaaaaaaaga agctacaact agtactgaac
     1201 caccaacaga attatctggt gagattacaa tgtggcactc ctttactcaa ggaccccgtt
     1261 tagaaagtat tcaaaaatca gcagatgctt tcatgcaaaa gcatccaaaa acgaaaatca
     1321 agattgaaac attttcttgg aatgacttct atactaaatg gactacaggt ttagcaaatg
     1381 gaaatgtgcc agatatcagt acagctcttc ctaaccaagt aatggaaatg gtcaactcag
     1441 atgctttggt tccgctaaat gattctatca agcgtattgg acaagataaa tttaacgaaa
     1501 ctgccttaaa tgaagcaaaa atcggagatg attactactc tgttcctctt tattcacatg
     1561 cacaagtcat gtgggttaga acagatttgt taaaagaaca taatattgag gttcctaaaa
     1621 cttgggatca actctatgaa gcttctaaaa aattgaaaga agctggagtt tatggcttgt
     1681 ctgttccgtt tggaacaaat gacttaatgg caacacgttt cttgaacttc tacgtacgta
     1741 gtggtggagg aagcctctta acaaaagatc ttaaagcaga cttgacaagc caacttgctc
     1801 aagatggtat taaatactgg gttaaattgt ataaagaaat ctcacctcaa gattctttga
     1861 actttaatgt ccttcaacaa gctaccttgt tctatcaagg aaaaacagca tttgacttta
     1921 actctggctt ccatatcgga ggaattaatg ccaacagtcc tcaattgatt gattcgattg
     1981 atgcttatcc tattccaaaa atcaaagagt ctgataaaga ccaaggaatt gaaacctcaa
     2041 acattccaat ggttgtttgg aaaaattcaa aacatccaga agttgctaaa gcattcttag
     2101 aagcacttta taatgaagaa gactacgtta aattccttga ttcaactcca gtaggtatgt
     2161 tgccaactat taaggggatt agcgattctg cagcctataa agaaaatgaa actcgtaaga
     2221 aatttaaaca tgctgaagaa gtaattactg aagctgttaa aaaaggtact gctattggtt
     2281 atgaaaatgg accaagtgta caagctggta tgttgactaa ccaacacatt attgaacaaa
     2341 tgttccaaga tatcattaca aatggaacag atcctatgaa agcagcaaaa gaagcagaaa
     2401 aacaattaaa cgatttattt gaggctgttc agtagatgta aaagactaga aaataggtgg
     2461 gctagtgagc tgaaaagctc tagcccaatc ttgtaaaaga agggagaagg agaatggtta
     2521 aagaacgtaa tttaactcgc tggatatttg ttttgccagc tatgattatc gtaggattac
     2581 tctttgttta tccgtttttc tcgagtattt tttatagctt taccaataag catttgatta
     2641 tgcctaatta taaatttgtt ggtttggcta actataaagc tgtgctatca gatcccaact
     2701 tctttaatgc gttctttaat tcaattaagt ggaccgtttt ctcattagtt ggtcaagttt
     2761 tagtagggtt tgtattggct ttagctcttc acagagtacg ccacttcaag aaattatata
     2821 ggaccttatt gattgttcct tgggcatttc ctaccatcgt tattgccttc tcttggcagt
     2881 ggattataaa cggggtttat ggctacttac ctaatctaat cgtaaaatta ggtttaatgg
     2941 aacatacacc tgcatttttg acagatagta catgggcatt cctatgtttg gtgtttatca
     3001 acatttggtt tggagcacca atgattatgg ttaatgtgct ttcagctttg caaacagtac
     3061 cagaagaaca atttgaggct gctaagatag atggtgcttc aagttggcag gtgttcaagt
     3121 ttatcgtctt tccacatatt aaagtggttg taggacttct agttgttttg agaactgtat
     3181 ggatctttaa taactttgac attatctacc tcattactgg tggtggacca gccaatgcta
     3241 caacgacgct tccaattttt gcttacaacc tgggttgggg aactaaattg ttgggtcgtg
     3301 cttcagcagt tacagtattg ctctttatct tcttggtggc gatttgcttt atctactttg
     3361 ctatcatcag taagtgggaa aaggagggta gaaaataatg aagaagaaat ccagtattta
     3421 tttagatatt ctctcacatg tacttttagt tggtgcgacc atcgttgcaa ttttcccatt
     3481 ggtatggatt atcatatctt ctgtcaaagg gaaaggggaa ttaactcagt atccaacacg
     3541 attttggcct gaacagttta cattagatta tttcactcat gttatcaacg atttgcactt
     3601 cattgataac attcgaaaca gtttaatcat tgccttggct acaaccctca ttgcgattat
     3661 tatttctgct atggcagcct atggtattgt tcgattcttt cctaaattgg gagcaatcat
     3721 gtcgagacta ctcgtcatta cctacatttt cccaccaatt ttgttagcaa ttccctattc
     3781 aattgccatt gctaaagttg ggttaacaaa tagtttattt ggcttgatga tggtttatct
     3841 atcttttagt gttccatatg cagtttggct cttagttgga tttttccaaa cagttccaat
     3901 tggaattgaa gaagcggcta gaattgatgg tgcaaataaa tttgttacgt tttataaagt
     3961 tgtgctaccg attgtagcac caggtattgt agcaacagct atttatacat ttatcaatgc
     4021 ttggaatgaa ttcctgtatg ccttgatttt gattaacaat acaggaaaga tgacagtagc
     4081 agtagccctt cgttcactta atggttcaga aatactagac tggggagata tgatggcagc
     4141 gtctgttatt gtagttcttc catcaattat tttcttctct atcatccaaa ataagattgc
     4201 aagtggatta tcagaaggat ctgtgaagta gacgaaagaa ggaaaaaaat gaataaaaga
     4261 ggtctttatt caaaactagg aatttctgtt gtaggcatta gtcttttaat gggagtcccc
     4321 actttgattc atgcgaatga attaaactat ggtcaactgt ccatatctcc tatttttcaa
     4381 ggaggctcat atcaactgaa caataagagt atagatatca gccctttgtt attagataaa
     4441 ttgtctggag agagtcagac agtagtaatg aaatttaaag cagatgaacc aaactctctt
     4501 caagctttgt ttggcctatc taatagtaaa gcaggcttta aaaataatta cttttcaatt
     4561 ttcatgagag attctggtga gataggtgta gaaataagag acgcccaaaa gggaataaat
     4621 tatttatttt ccagaccagc ttcattatgg ggaaaacata aaggacaggc agttgaaaat
     4681 acactagtat ttgtatctga ttctaaagat aaaacataca caatgtatgt taatggaata
     4741 gaagtgttct ctgaaacagt tgatacattt ttgccaattt caaatataaa tggtatagat
     4801 aaggcaacac taggagctgt taatcgtgaa ggtaaggaac attacctcgc aaaaggaagt
     4861 attggtgaaa tcagtctatt taacaaagca attagtgatc aggaagtttc aactattccc
     4921 ttatcaaatc catttcagtt aattttccaa tcaggagatt ctactcaagc taactatttt
     4981 agaataccga cactatatac attaagtagt ggaagagttc tatcaagtat tgatgcacgt
     5041 tatggtggga ctcatgattc taaaagtaag attaatattg ccacttctta tagtgatgat
     5101 aatgggaaaa cgtggagtga gccaattttt gctatgaagt ttaatgacta tgaggagcag
     5161 ttagtttact ggccacgaga taataaatta aagaatagtc aaattagtgg aagtgcttca
     5221 ttcatagatt catccattgt tgaagataaa aaatctggga aaacgatatt actagctgat
     5281 gttatgcctg cgggtattgg aaataataat gcaaataaag ccgactcagg ttttaaagaa
     5341 ataaatggtc attattattt aaaactaaag aagaatggag ataacgattt ccgttataca
     5401 gttagagaaa atggtgtcgt ttatgatgaa acaactaata aacctacaaa ttatactata
     5461 aatgataagt atgaagtttt ggagggagga aagtctttaa cagtcgaaca atattcggtt
     5521 gattttgata gtggctcttt aagagaaaaa cataatggaa aacaggtccc tatgaatgtt
     5581 ttctacaaag attcgttatt taaagtgact cctactaatt atatagcaat gacaactagt
     5641 cagaatagag gagagagttg ggaacaattt aagttgttgc ctccgttctt aggagaaaaa
     5701 cataatggaa cttacttatg tcccggacaa ggtttagcat taaaatcaag taacagattg
     5761 atttttgcaa catatactag tggagaacta acctatctca tttctgatga tagtggtcaa
     5821 acatggaaga aatcctcagc ttcaattccg tttaaaaatg caacagcaga agcacaaatg
     5881 gttgaactga gagatggtgt gattagaaca ttctttagaa ccactacagg taagatagct
     5941 tatatgacta gtagagattc tggagaaaca tggtcggaag tttcgtatat tgatggaatc
     6001 caacaaactt catatggcac acaagtatct gcaattaaat actctcaatt aattgatgga
     6061 aaagaagcag tcattttgag tacaccaaat tctagaagtg gccgtaaggg aggtcaatta
     6121 gttgtcggtt tagtcaataa agaagatgat agtattgatt ggaaatacca ctatgatatt
     6181 gatttgcctt cgtatggtta tgcctattct gcgattacag aattgccaaa tcatcacata
     6241 ggtgtactgt ttgaaaaata tgattcgtgg tcgagaaatg aattgcattt aagcaatgta
     6301 gttcagtata tagatttgga aattaatgat ttaacaaaat aaaggagaaa aacatggtta
     6361 aatacggtgt tgttggagca gggtattttg gagctgaatt ggctcgctac atgcaaaaga
     6421 atgatggagc agagattact cttctctatg atccagataa tgcagaggcg attgcagaag
     6481 aattgggagc aaaagtagca agttccttag atgagttggt ttctagcgat gaagtagatt
     6541 gtgttatcgt cgcaactcca aataatcttc ataaggaacc ggttattaag gctgcacagc
     6601 atggtaaaaa tgttttctgt gaaaaaccaa ttgcgctttc ttatcaagat tgtcgcgaga
     6661 tggtagatgc gtgtaaagaa aacaatgtaa cctttatggc aggacatatt atgaatttct
     6721 ttaatggtgt tcatcatgca aaagaactca ttaatcaagg agttatcgga gacgttctat
     6781 attgtcatac agctcgtaat ggttgggaag aacaacaacc gtcagtatca tggaaaaaaa
     6841 ttcgtgaaaa atcaggtggt cacttgtatc accacatcca tgaattggat tgcgttcaat
     6901 tccttatggg gggcatgcct gaaactgtaa ccatgacagg tggaaatgtg gcccatgaag
     6961 gtgaacattt cggtgatgaa gatgatatga tttttgtcaa tatggaattt tctaataagc
     7021 gttttgcttt gttagaatgg ggttcagctt atcgttgggg tgaacattat gtcttaatcc
     7081 aaggaagcaa aggtgccatc cgcttagact tattcaactg taaaggaact cttaagctag
     7141 atgggcaaga aagctatttc ttgattcacg aatcgcaaga agaagatgat gatcggactc
     7201 gtatctatca tagtacagag atggatggag caattgctta tggtaaacca ggtaaacgta
     7261 ctccattatg gctatcatct gtcattgata aagaaatgcg ctatctgcat gagattatgg
     7321 aaggagctcc agtatcagaa gaatttgcaa aacttttgac aggtgaagct gccctagaag
     7381 caattgctac tgcagatgct tgtacccagt ctatgtttga agatcgcaaa gtaaaattgt
     7441 cagaaattgt aaaataaatt ttggtattct cctatttata ggtcgacttg ctcctctgaa
     7501 agtactttta gaggagctgt ttgactttgc tagtttttga aactgaaatc tattatacta
     7561 caaactattg aaagcgtttt aattttaagg tataataatc tcatagaaat aaagaaaagg
     7621 aggaaagagg atgccacaga ttagcaaaga agccttgatt gagcaaatca aagatggaat
     7681 catcgtttct tgtcaggctc ttcctcatga accgctttat acagaagcgg gaggggtgat
     7741 tcccttgctg gtcaaagcgg ctgagcaagg tggagcagtc ggtatccgag caaacagtgt
     7801 tcgcgatatc aaggaaatta aggaggtcac taaacttcca atcattggga ttatcaaacg
     7861 tgattatcca cctcaggaac ccttcatcac ggctactatg aaagaagttg atgaattggc
     7921 agaactggac atcgaggtga ttgctctgga ttgtaccaag cgtgaacgct acgatggttt
     7981 ggaaattcaa gagttcattc gtcaggttaa ggagaaatat cctaatcagc ttttgatggc
     8041 tgatactagt atcttcgaag aagggctagc agctgtagaa gcaggaattg actttgtcgg
     8101 aacaacctta tcaggctaca catcctacag tccaaaagta gacggtccag attttgaatt
     8161 gattaagaaa ctctgtgatg ccggtgtaga tgtcattgca gaaggaaaaa ttcatacacc
     8221 agaacaagcc aaacaaatcc ttgaatatgg agtgcgaggc atcgttgttg gtggcgccat
     8281 tactagacca aaagagatta cagaacgctt cgttgctagt cttaaataag atgtgagggg
     8341 gagttttatg tttaaagttt tacaaaaagt tggaaaagct tttatgttac ctatagctat
     8401 acttcctgca gcaggtctac ttttggggat tggtggtgca ctttcaaacc caaccacgat
     8461 agcaacttat ccaatactag acaatagtat ttttcaatca atattccaag taatgagctc
     8521 tgcaggagag gttgtattca gtaatttgtc actacttctc tgtgtgggat tatgtattgg
     8581 cttagcgaaa cgagataaag gaaccgctgc gttagcagga gtaactggtt acttagttat
     8641 gactgcaacg atcaaagctt tggtaaaact ttttatggca gaaggatctg caattgatac
     8701 tggagttatt ggagcattag ctgtcggaat agttgccgta tatttgcaca accgatataa
     8761 caatattcaa ttaccttccg ctttaggatt ctttggaggt tcacgcttcg ttcctattgt
     8821 tacatcgttc tcttctatct tgattggctt tgtcttcttt gttatttggc cacctttcca
     8881 acaacttctt gtttctacag gtggatatat ttctcaggcg ggtccaattg gaacttttct
     8941 atatggattt ttaatgagac tttctggagc agtaggctta catcatataa tttaccctat
     9001 gttttggtat actgaacttg gtggtgttga aactattgca ggacaaacag tggttggagc
     9061 tcaaaaaata ttttttgctc aattagccga tccggcccat tctggattat ttacagaagg
     9121 aacaaggttt tttgcaggtc gtttctcaac aatgatgttc ggtttaccgg ctgcctgttt
     9181 agcgatgtac catagtgttc ctaaaaatcg tcgtaaaaaa tacgcgggtt tgttttttgg
     9241 agttgcttta acatctttta ttaccggtat tacagaacca attgaattta tgtttctatt
     9301 cgtcagtccg gttctatatg ttgttcacgc attccttgat ggtgttagct tctttattgc
     9361 agacgtctta aatatttcaa taggaaacac attttcagga ggtgtaatcg atttcacttt
     9421 atttggaatt ttgcagggga acgctaagac gaattgggtt cttcagattc caattggact
     9481 tatttggagt gttttgtatt atattatttt tagatggttc attactcaat tcaatgttct
     9541 aacgccagga cgaggagaag aagtagattc taaagaaatt tctgaatccg cagattcaac
     9601 ttcaaatact gcagattatt taaaacagga tagcctacaa attatcagag ccttgggtgg
     9661 atcaaataat atagaagatg tagatgcttg tgtgacacgt ttacgtgtag ctgtaaaaga
     9721 agttaatcaa gttgataaag cacttttaaa acaaattggt gcagttgatg tcttagaagt
     9781 gaagggtggc attcaagcaa tctatggagc aaaagcaatc ttatataaaa atagtattaa
     9841 tgaaatttta ggtgtagatg attaagtact tactgactta ataaaaaaca gaggagagtg
     9901 atggatgagt aggatgaaat gaaatcgcat acaagaaata aagaactcat tatccaagtt
     9961 ggatacgctt attacatagg agaatacaaa tgaaatttag aaaattagct tgtacagtac
    10021 ttgcgggtgc tgcggttctt ggtcttgctg cttgtggcaa ttctggcgga agtaaagatg
    10081 ctgccaaatc aggtggtgac ggtgccaaaa cagaaatcac ttggtgggca ttcccagtat
    10141 ttacccaaga aaaaactggt gacggtgttg gaacttatga aaaatcaatc atcgaagcgt
    10201 ttgaaaaagc aaacccagat ataaaagtga aattggaaac catcgacttc aagtcaggtc
    10261 ctgaaaaaat cacaacagcc atcgaagcag gaacagctcc agacgtactc tttgatgcac
    10321 caggacgtat catccaatac ggtaaaaacg gtaaattggc tgagttgaat gacctcttca
    10381 cagatgaatt tgttaaagat gtcaacaatg aaaacatcgt acaagcaagt aaagctggag
    10441 acaaggctta tatgtatccg attagttctg ccccattcta catggcaatg aacaagaaaa
    10501 tgttagaaga tgctggagta gcaaaccttg taaaagaagg ttggacaact gatgattttg
    10561 aaaaagtatt gaaagcactt aaagacaagg gttacacacc aggttcattg ttcagttctg
    10621 gtcaaggggg agaccaagga acacgtgcct ttatctctaa cctttatagc ggttctgtaa
    10681 cagatgaaaa agttagcaaa tatacaactg atgatcctaa attcgtcaaa ggtcttgaaa
    10741 aagcaactag ctggattaaa gacaatttga tcaataatgg ttcacaattt gacggtgggg
    10801 cagatatcca aaactttgcc aatggtcaaa catcttacac aatcctttgg gcaccagctc
    10861 aaaatggtat ccaagctaaa cttttagaag caagtaaggt agaagtggta gaagtaccat
    10921 tcccatcaga cgaaggtaag ccagctcttg aataccttgt aaacgggttt gcagtattca
    10981 acaataaaga cgacaagaaa gtcgctgcat ctaagaaatt catccagttt atcgcagatg
    11041 acaaggagtg gggacctaaa gacgtagttc gtacaggtgc tttcccagtc cgtacttcat
    11101 ttggaaaact ttatgaagac aaacgcatgg aaacaatcag cggctggact caatactact
    11161 caccatacta caacactatt gatggatttg ctgaaatgag aacactttgg ttcccaatgt
    11221 tgcaatctgt atcaaatggt gacgaaaaac cagcagatgc tttgaaagcc ttcactgaaa
    11281 aagcgaacga aacaatcaaa aaagctatga aacaatagtc cttagttatt ctataaaaag
    11341 tagtttttta aagaacctaa gagtgtatac ccccttttcc ctctacacag atagtgtaag
    11401 aaaagggggc ttttgtttaa aatgtaagaa actgtcacga aattaaaatg aagttcttac
    11461 ataagcgaat cataaaaaat ttcattttga ttttaaaaca gttcaagaaa gtcaaaaaat
    11521 tattctattt gaaagagagg tgccgactgt gaaagtcaat aaaatccgta tgcgggaaac
    11581 agtgatttcc tacgctttcc tagcaccagt attattcttc tttgtcatct ttgtgttggc
    11641 tccgatggtg atgggcttca ttacaagttt ctttaactac tcaatgacta aatttgagtt
    11701 tgtaggcttg gataactata tccgtatgtt taaagatcct gtctttacaa aatctctgat
    11761 taacacagtt attttggtta ttggatctgt accagttgtt gttctattct cactctttgt
    11821 agcatctcag acctatcatc aaaatgtcat tgccagatcc ttctaccgtt tcgtcttctt
    11881 ccttcctgtt gtaacgggta gtgttgccgt gacagttgtt tggaaatgga tttatgaccc
    11941 actatcaggg attctaaact ttgtccttaa gtccagccac atcatcagcc aaaacatttc
    12001 ttggttggga gataaaaact gggcattgat ggcgattatg attattctct tgaccacttc
    12061 agttggtcag cccatcatcc tttatatcgc tgccatgggg aatattgaca attcactggt
    12121 tgaagcggcg cgtgttgatg gtgcaactga gtttcaagtt ttttggaaga ttaaatggcc
    12181 aagccttctt ccaacaactc tttatattgc aatcatcaca acaattaact cattccagtg
    12241 ttttgccttg attcagcttt tgacatctgg tggtccaaac tactcaacaa gtaccttgat
    12301 gtactacctt tacgaaaaag ccttccaatt gacagaatac ggctatgcca acacaattgg
    12361 tgtcttcttg gcaatcatga ttgctatcgt aagctttgtt caatttaaag tacttggaaa
    12421 cgacgtagaa tactaaagaa aggagacagc tatgcaatct acagaaaaaa aaccattaac
    12481 agcctttact gttatttcaa caatcatttt gctcttgttg actgtgctgt tcatctttcc
    12541 attctactgg attttgacag gggcattcaa atcacaacct gatacaattg ttattcctcc
    12601 tcagtggttc cctaaaatgc caaccatgga aaacttccaa caactcatgg tgcagaaccc
    12661 tgccttgcaa tggatgtgga actcagtatt tatctcattg gtaaccatgt tcttagtctg
    12721 tgcaacctca tctctagcag gttatgtatt ggctaaaaaa cgtttctatg gtcaacgcat
    12781 tctatttgct atctttatcg ctgctatggc gcttccaaaa caagttgtcc ttgtaccatt
    12841 ggtacgtatc gtcaacttca tgggaatcca cgatactctc tgggcagtta tcttgccttt
    12901 gattggatgg ccattcggtg tcttcctcat gaaacagttc agtgaaaata tccctacaga
    12961 gttgcttgaa tcagctaaaa tcgacggttg tggtgagatt cgtaccttct ggagtgtagc
    13021 cttcccgatt gtgaaaccag ggtttgcagc ccttgcaatc tttaccttca tcaatacttg
    13081 gaatgactac ttcatgcaat tggtaatgtt gacttcacgt aacaatttga ccatctcact
    13141 tggggttgcg accatgcagg ctgaaatggc aaccaactat ggtttgatta tggcaggagc
    13201 tgcccttgct gctgttccaa tcgtcacagt cttcctagtc ttccaaaaat ccttcacaca
    13261 gggtattact atgggagcgg tcaaaggata atactctgag aaaatctctt caaactacgt
    13321 cagcgtcacc ttgccatact taagtattgc ctgcggttag cttcctagtt tgttcttcaa
    13381 ttttcattga gtataggaaa atcaatctat caagatacag aagtatattt tatagattta
    13441 gagaatatag aggttataag tgtctacaaa atggagggta tgcagttact ttatgaagtt
    13501 ttgtcagaca cttataaact taagaatggt tttagttaac tatcagaaac gaaggaaaga
    13561 gtatgatttt tgacgatttg aaaaacatca ccttttacaa agggattcat cccaatttag
    13621 acaaggctat cgactatctc taccaacatc gtaaagattc attcgaatta ggaaagtatg
    13681 agattgatgg agataaagtc tttctagttg ttcaggaaaa tgtcctcaat caagttgaga
    13741 ataatcgatt tgaacaccat aagaactatg cagatttgca tttgctgata gaagggcatg
    13801 aatattcgag ctacggttca cgtatcaaag acgaggcagt agcattcgac gaagcgagtg
    13861 acattggctt tgttcattgt catgaacact acccactctt gttgggttat cacaattttg
    13921 cgattttctt cccaggtgag ccacatcagc caaatggtta tgcaggcatg gaagaaaagg
    13981 ttcgaaaata tctctttaaa attttgattg attaaaaata ggatgaattg tttttttgta
    14041 aagctttgat aatactctac catgaaattg atctttgtga ggtagagaaa tgagaataaa
    14101 atatttaaaa attggtatct tctaagtatg ctgcaagagc tagtttctta gatggacagg
    14161 ggattacagt tgatgagatg gcttggataa ttaggggcat tgtgactgca ttgattggta
    14221 gatacataaa attaggtact tatgcagtta agtatggtat tagtatggcg cgctcgatct
    14281 taagtagggc agctgcaact gcggcagcaa gagtaggatt attgactaag atttttggat
    14341 ggattttacg aatagctgtg ctcgcagctg atgtatatgg taattttgcc aacaatattg
    14401 ctgtagcttg ggatgcacat gataaaatcc ctaacaatgg tcgtataaac ttttaaaatg
    14461 cgagaatgaa agcactttgt atttttttat tgtatatgtt agcttggaca gtgcttgcaa
    14521 tgataatccg tggagggcta gatggatttg atgaacacac ttggcgtact attttaattg
    14581 cttcgctgtc cgggatatat atagattata tgtccataga taaaagtaga aaaaagtcca
    14641 aaagaaaaaa gaaaaaatag atttgttcat ggtagggact tatgaaagct ttactgacaa
    14701 aaaagaaaac agtttacaaa gaaaaatgat ggaggagcaa acatggcaca aaaaggagta
    14761 agccttatca aggcagcatt tgatacagat aactttctca tgcgttttag tgagaaagtc
    14821 ttggacatcg tgacagccaa tcttcttttt gtcgtctctt gtttgcccat cgtgacgatt
    14881 ggagtggcta aaatcagcct ctacgagacc atgttcgaag ttaagaagag cagacgggtg
    14941 cctgttttta aaatctatct aagatctttc aagcaaaatc tgaaactagg tcttcagctg
    15001 ggtttaatgg agttaggaat tgtgtttctt accctttcag atctctatct tttctggggt
    15061 caaacagctc tgcccttcca attgctgaaa gccatttgtc taggcattct gattttcctt
    15121 acgattgtga tgttggctag ctatccaatc gcggcacgtt atgatttaac ttggaaagaa
    15181 gtgttacaaa aagggcttat cttggctagt tttaactttc cttggttctt cctcatgtta
    15241 gccattcttg tcctcattgt gatggttctt tatctgtccg ccttcagtct actcttaggt
    15301 ggctcagtct tcctactttt tgggtttgga ctattggtct ttatccagac tggattgatg
    15361 gagaaaattt tcgcaaaata ccaataggag ccttatttct gaaactactt tcaaaggctc
    15421 caaacgctat tctataagcg agaaactaaa atctaagtgt ctataagata ttgaaagcct
    15481 tttcggtaaa gtgtatacta aagaagtaaa gaaaaatctg ctttagcaga aaataaaaat
    15541 aataggagaa aatctatgtc agatttgaaa aaatacgaag gtgtcattcc agccttctac
    15601 gcatgttatg atgagcaagg agaagtaagt ccagagcgta cgcgtgcctt ggttcaatac
    15661 ttcattgata aaggtgttca aggtctttat gtcaatggtt cttctggtga atgtatctac
    15721 caaagcgttg aagatcgcaa gttgattttg gaagaagtca tggcggtagc caaaggtaaa
    15781 ttgaccatta ttgcccatgt tgcttgcaat aatactaaag atagtatgga acttgctcgc
    15841 catgctgaaa gcttgggagt agatgctatt gcaacgattc caccaattta cttccgcttg
    15901 ccagaatact cagttgccaa atactggaac gatattagtt ctgcagctcc aaacacagac
    15961 tacgtgattt acaacattcc tcaattggca ggggttgctt tgacttcaag cctttacaca
    16021 gaaatgttga aaaatcctcg tgttatcggt gttaagaact cttcaatgcc agttcaagat
    16081 atccaaacct ttgtcagcct tggcggggaa gaccatattg tctttaacgg tccagatgaa
    16141 cagttcctag gtggccgcct catgggtgct aaggctggta tcggtggtac ttatggtgct
    16201 atgccagaac tcttcttgaa actcaatcag ttgattgcgg ataaagattt agaaacagcg
    16261 cgtgaattgc agtatgctat caacgcaatc attggtaaac tcactgctgc acatggaaat
    16321 atgtacggtg tcatcaaaga agttttgaag atcaatgaag gcttgaatat tggttctgtt
    16381 cgttcaccat tgacaccagt gactgaagac gatcgtccag ttgtagaagc ggctgcagcc
    16441 ttgattcgtg aaaccaagga gcgcttcctc taatctaaaa ggaggtattt atgacatact
    16501 acgttgcaat tgatatcggt ggaactaaca tcaagtatgg tttggttgat caagaggggc
    16561 aacttcttga atcacatgaa atgccaacag aggcgcataa gggtggacct catatcttac
    16621 aaaagaccaa agatatcgta gctagttatt tagaaaaagg cccagtagca ggtgttgcca
    16681 tatcttctgc tgggatggtg gatccggata agggtgagat tttctatgct gggccgcaaa
    16741 tccctaacta cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt actattcctt
    16801 gtgagattga aaatgatgtc aactgtgcag gtcttgctga ggcagtatct ggttcaggca
    16861 agggagcaag tgtgacactt tgcttgacca ttggaaccgg tatcggtggt tgcttgatta
    16921 tggataggaa agtcttccat ggttttagta attcagcctg tgaagtcggg tatatgcata
    16981 tgcaggatgg agcttttcag gatctcgctt ctacaacagc tttagtgaaa tatgtagctg
    17041 aagcccatgg agaagatgtt gatcagtgga atggccgacg tatctttaag gaagctactg
    17101 aaggaaacaa aatctgcatg gaaggtattg accgtatggt tgactatcta ggaaaaggtc
    17161 tggcaaatat ttgctacgtt gccaatccag aagtggtcat tcttggtggt ggtatcatgg
    17221 ggcaagaggc tatcctcaaa cctaagatcc gcacagcctt gaaagaggct ttggtaccaa
    17281 gtttagcaga aaaaacacga ttagaatttg cccatcacca aaatacagca gggatgttgg
    17341 gtgcatatta tcattttaag acaaaacaat c
//
LOCUS       DBERCW010000039        16674 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.039, whole genome shotgun sequence.
ACCESSION   DBERCW010000039 DBERCW010000000
VERSION     DBERCW010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.039"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            87..3437
                     /locus_tag="ACL72M_001703"
     CDS             87..3437
                     /locus_tag="ACL72M_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS0716799.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(3943..4413)
                     /locus_tag="ACL72M_001704"
     CDS             complement(3943..4413)
                     /locus_tag="ACL72M_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0716800.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4430..6703)
                     /locus_tag="ACL72M_001705"
     CDS             complement(4430..6703)
                     /locus_tag="ACL72M_001705"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGS0716801.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7050..10151
                     /locus_tag="ACL72M_001706"
     CDS             7050..10151
                     /locus_tag="ACL72M_001706"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGS0716802.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10234..11241
                     /gene="pfkA"
                     /locus_tag="ACL72M_001707"
     CDS             10234..11241
                     /gene="pfkA"
                     /locus_tag="ACL72M_001707"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGS0716803.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11300..12805
                     /gene="pyk"
                     /locus_tag="ACL72M_001708"
     CDS             11300..12805
                     /gene="pyk"
                     /locus_tag="ACL72M_001708"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGS0716804.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(13550..13765)
                     /locus_tag="ACL72M_001709"
     CDS             complement(13550..13765)
                     /locus_tag="ACL72M_001709"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGS0716805.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGYLK
                     KTQSRILRHPPRRKQPYSYHRKSCQAI"
     gene            14613..15485
                     /locus_tag="ACL72M_001710"
     CDS             14613..15485
                     /locus_tag="ACL72M_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGS0716806.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(15631..15975)
                     /locus_tag="ACL72M_001711"
                     /pseudo
     CDS             complement(15631..15975)
                     /locus_tag="ACL72M_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            16118..16430
                     /locus_tag="ACL72M_001712"
                     /pseudo
     CDS             16118..16430
                     /locus_tag="ACL72M_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16434..16674
                     /locus_tag="ACL72M_001713"
                     /pseudo
     CDS             16434..16674
                     /locus_tag="ACL72M_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
BASE COUNT         5156 a         2841 c         3563 g         5114 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctctgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctttggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggttga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaactagct gcaggctgct caaaacactg ttttgaggtt gtagatggaa
     3781 gctgacgcgg attgaagaga ttttcgaaga gtataaatct tcctaggata aagcaaaacg
     3841 catagtatca agggttttca acacttgata ctatgcgttt tctgatgtta aagactttct
     3901 accaggtttt ttaaaagcat aattgttagt tgtagtcatt tattattctt caaagaaaaa
     3961 tggtggggcg aattttttca gttcttcaaa gcacttttga gcagtatctg catcttcaca
     4021 gatgataaga cagacatcat taccacaaag ggtagcgata gcgtcaggga agctcaaagt
     4081 atcaatgata gaaccaaagg attgagccag tccaggaagg gtttttagta ggacttggtg
     4141 ttgaactggg cgcatccaga caagggcgtc ttccatgtag agttcgagac gtttttccca
     4201 ttttgagatg gaaccattgt taagaacata ataagcgcta tcttcttcgc ggacttttga
     4261 taggttcata tttttgatgt cgcgtgagag ggttgcctgg gttacttgaa tgtcgttctc
     4321 agcaagaagg gcttgcaact cagcctgtgt atgaatcttg ttttttgtga taagagcgcg
     4381 tataagttgg tggcggtgtt ctgatttatt cataataatg taactccttt tagcaaggta
     4441 aggtaagcat ggactgagcg aggtcgacag tcaagtggta gtctgtattg tcacggatgg
     4501 tgatttcaaa gtcagtagta tagaggacta aacggagagt gtctccttct tttagcttgt
     4561 aaatagttgg ctgcagttca aattgaacgt ccatccattc atctgcagta atatcctcta
     4621 ctaacagtaa atcatttcta ttttgtaaat taaggtaacc ttttgtcacg actcgttgtg
     4681 cctctggtct aaatggcaat tcacagagat tttccaacat gtgatagcga ccgttgtcaa
     4741 tggttctagc acttaaaata gctggataag gttgtaggta tttcttttgc ccaaattcta
     4801 gcagttgggc agataagagc cccttgtttg tactggattt gatacgaaga ttgagctgag
     4861 cgcgaccgtt taggtggaga tctttagtca caggaaggtt aatagtaatc tgattggctt
     4921 tcccttgata gagctctgta ttgaaggttt ggtatgtctt accatagcgc tcaaaatcct
     4981 tatctgggta ctggttttga atagcttgct cttcttgacc aagtgagaag gtttcacagt
     5041 tttcttgccc accgaagtta tcaagtgata accaagtctg tggagctgta ttgtcctgcc
     5101 agataacagt aggaagttga aagtctgttt cctgtcctag taatttcttg gtcaataagg
     5161 catttatgga ctcacggaag tcaattgatt gccaattgtt catgtaaaca tgggcaccat
     5221 tatggaaaaa gagatgcttg tgtatatgag taggaagagc atggaacatc tggtaaacat
     5281 gaagtggttt gacattccaa tcctgagaac catgagtaaa gacaacctct gcctttactt
     5341 tatgggcatt gagcagataa ttgcggtcat gccaaaactg attgtagtcc ccagtttttc
     5401 ggtctagctg agctttcact ttttctaagt cagcttggtg agcttcattg ccacggatat
     5461 agtcgccagc taagagatta cgagaatagg ttaactcagc aagggagtca aagtcctcac
     5521 ctggataacc acctgggcta gtcaccagac cgttttcacg gtagtagttg taccatgatg
     5581 aaattcctgc ctcggcaatg ataacttcta aaccatcgac tcctgtagtc gcaagaccat
     5641 tggacatggt acctagatag gaaagtcctg ttgtagcaac ttttccgttt gaccaatcag
     5701 ccttgacttg acgctggcgc gtgtgatcag taaaggcacg gcaacggccg ttaagccaat
     5761 cgatgacatt tttataagcc tcgatttgct ggtagtctcc attagtcatg aaacctgtcg
     5821 agtctttggt accaacacct gagacataga gattggcaaa gcctctcgga aggaagtagt
     5881 cgtttagtgt atagctagag ttgatgtgag ttagcttttc ctcagcctct gctataagct
     5941 cagctttacc ttggggttgg acgagattta gttgaggttt ctctagctca atcttgtgag
     6001 gaagtttaac ctcaagctcg ccctccatct tgtagagagc cttgtcacta gccttgtcat
     6061 tggttccctg atgataaggg ctggctgtca tgatggcagg gatttttcca tcaaaacgag
     6121 ggcgaataat gctaaccttt actaggtctg atagcccttt ttggtcagta tcgacacgag
     6181 actcaacgta aacgacttca cgaatgacat cctggttaga aaaagtagcc aaactcttgc
     6241 cgttaaagta gtggtagtca ttatcctccg gaataagacc atcactaaca agttggtcga
     6301 taagagtatt tccttttttg gtgcgagtat tgagtaactg atagagattt tcaatcaagt
     6361 caccatatat aatgggaaat ccagtttctt tacgaaaaac gtcactatct tcgaagtcaa
     6421 ccaaataaga aaagcctaaa agttgaaaag caacagtata aaaaatatct gctgtcagtt
     6481 catcttctga ttgaaaaaat gtcagcaggt ctgttttttt atcagctgct aggatagaaa
     6541 gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg taaaaaggtt tcaagtgagt
     6601 ctttgtgatt ggctgtattt tgtaaatcaa agccacattt ttttagttca gataagacat
     6661 tttcttttgg aaaattgata taactatatt gattaaaacg catagaacct ccatatagaa
     6721 tgacagttaa ggttattata tcaaaaaaaa agcagaaagg gaattgttaa cttcaaaagg
     6781 aaataatcca ataaaaatga ataaagtact aaattcaata tagagaacag agtaacaata
     6841 agaataaata gatagggtat aaaagttcta ggagatttat attatatgct ttctattttt
     6901 atatacaata tagtataaat ataaaaatga tgacaaaaat acaaatgaat agaaaataaa
     6961 ttagtaagct gatgaaattt ttctcaagag aagccattta taggtgaaaa tggtataata
     7021 tagtgagaag gatagaggag aagtgtaaat tgatcgcaca actagataca aaaacagtct
     7081 atagttttat ggaaagcgtc atttcgatcg aaaagtatgt gagagcagct aaagaatacg
     7141 gctacactca tttggctatg atggatattg acaatcttta tggcgctttc gactttctag
     7201 agattacaaa aaaatacggc attcatcctt tgctagggct tgaaatgaca gtgtttgtag
     7261 atgatcagga agtgaatttg cgctttttag ctctatctag tgtgggctat cagcagttga
     7321 tgaagctttc gacagccaag atgcaggggg agaaaacttg gtcagtcctg tcccagtacc
     7381 tggaggatat cgcggtcatt gtgtcttatt ttgatagagt tgagtcgtta gaactaggct
     7441 gtgattacta tataggggtt tatccagaaa cactagcaag cgaatttcat catcctatct
     7501 tacctcttta tcgggtcaac gcttttgaaa gcagggatag agaagttctt caagttttaa
     7561 cagcgattaa agaaaatcta ccgctcagag aagttccctt gcgttcgaga caagatgtct
     7621 ttatatcagc aagttcttta gagaaactat tccaagagcg ttttccgcaa gctttggaca
     7681 atttagaaaa gcttatttca ggcatttctt acgacttgga tactagtctg aaactgcctc
     7741 gttttaatcc agctagacca gcagtagagg agttgagaga gcgtgctgaa ctggggcttg
     7801 ttcagaaggg gttgactagt aaagaatatc aagatagact agaccaagaa ttgtctgtta
     7861 ttcatgatat gggctttgat gattatttct tggttgtttg ggatttgttg cgttttggac
     7921 gatcgaatgg ctattatatg ggaatgggaa ggggttctgc agtaggcagt ttggtttctt
     7981 atgccttaga catcacgggg attgacccag tagagaaaaa tctgattttt gaacgctttc
     8041 ttaatcgtga acgctatacc atgcctgata ttgatattga tatcccagat atttatcgtc
     8101 cagattttat cagatatgtt ggtaataaat atggtagtaa acatgcggca caaatcgtta
     8161 ctttttcaac ctttggagcc aagcaagctc ttcgagatgt cttgaaacgc tttggtgtgc
     8221 cagagtatga attatctgca attactaaga aaatcagttt tcgtgacaat cttaagtcgg
     8281 cctatgaggg caatctccag tttcgtcagc aaatcaatag taagttagaa taccaaaaag
     8341 cttttgagat tgcttgcaag atagagggct atccaaggca aacctctgtc catgcggctg
     8401 gtgttgtaat tagtgaccaa gatttaacca actacattcc tctaaagtat ggtgatgaaa
     8461 ttccactgac tcagtatgat gctcatggag ttgaggctag cggacttttg aagatggact
     8521 ttctgggact acgaaatttg acctttgtcc agaagatgca agagttgctt gctgaaacag
     8581 aaggtattca tctgaaaatt gaagaaatcg atttagaaga caaagaaacg ttagctttat
     8641 ttgcctctgg taatacaaaa ggtatctttc aatttgagca accaggtgcc attcgtctgc
     8701 ttaagcgtgt gcaaccagtc tgttttgaag atgtcgtcgc gactacttct ctaaatcgac
     8761 caggtgcaag tgactacatc aataattttg tggcaaggaa gcatgggcag gaagaagtga
     8821 ctgttctaga ttcagctctg gaggatattt tggctccaac ttatggcatt atgctctatc
     8881 aggagcaggt tatgcaggtt gctcagcgat ttgctggatt tagtcttggg aaggccgata
     8941 ttttgcgtcg agctatgggt aaaaaggatg cctctgctat gcatgagatg agggcttcct
     9001 ttattcaagg ctccatagaa gcaggccata ctgcggaaaa agcagagcag gtttttgatg
     9061 ttatggagaa gtttgcaggt tatggattta atagatctca tgcctacgcc tactcagcct
     9121 tggccttcca gttggcttat ttcaaaacgc attatccagc cattttttat caggtcatgt
     9181 taaattattc caacagtgat tacttaatag atgcacttga agcaggtttt gaagtagcct
     9241 ctctatccat caatactatt ccctatcacg ataaaattgc caacaagtct atctatatag
     9301 gtttgaaatc gattaagggg ctcagcaagg acttggcgct ttggattatt gaacatagac
     9361 cttattctaa cattgaagat tttatagcta aattacctga gaattatctg aaacttcctc
     9421 tgctagaacc tttggtaaaa gttggtcttt tcgattcatt tgaaaaaaat cgtcaaaaag
     9481 tatttaataa cttagctaat ctatttgaat ttgtgaaaga gttgggaagt ttgtttggag
     9541 atgctattta tagttggcag gaatcggaag attggacgga acaagaaaaa ttttatatgg
     9601 aacaagagct tttagggata ggtgtcagca aacatccact acaagctatt gcaagtaagg
     9661 ctatttaccc gattacccca atcggaaatt tgtcagaaaa tagctatgct attattttgg
     9721 ttgaagttca gaaaataaaa gtgattcgta ccaaaaaggg tgaaaatatg gccttcttac
     9781 aggcagatga tagtaagaaa aaattggatg tcactctctt ttcagactta tatcgtcagg
     9841 ttggacagga aataaaagag ggagccttct actatgtaaa aggaaaaata caatcacgtg
     9901 atggccgtct gcaaatgatt gcacaagaaa taagagaagc agttgctgaa cgcttttgga
     9961 tacaggtgaa aaatcatgaa tcggatcaag aaatttcacg cattttagaa caatttaaag
    10021 gcccaatccc agtcatcatc cggtatgaag aggaacagaa aaccatcgtt tctccccatc
    10081 attttgtagc taaatccaat gaattagagg agaaattgaa tgaaatcgtt atgaaaacga
    10141 tttatcgcta aaaatacgga aaatagaaga attttaaaat caaatgtgat ataatcaaga
    10201 agaatgttaa aagaaaaagg agcataaacc aatatgaaac gtattgctgt tttgactagt
    10261 ggcggagacg cacctggtat gaacgctgcc atccgtgcag ttgttcgtca agcaatttca
    10321 gaaggaatgg aagtgtttgg tatctatgac ggatatgctg gtatggttgc cggtgaaatt
    10381 catcccctag atgcagcttc agtaggggac atcatttctc gtggtggtac ttttcttcac
    10441 tcagctcgtt atccagagtt cgctcaactt gaagggcaac ttaaagggat tgagcaattg
    10501 aaaaaacacg gaattgaagg tgtagttgtt atcggtggtg acggatctta ccacggcgct
    10561 atgcgtttga ctgaacatgg cttcccagct attggtcttc caggtacaat cgataacgat
    10621 atcgttggta ctgactttac aatcggtttt gacacagcgg ttactactgc catggacgct
    10681 atcgataaga ttcgtgatac atcatcaagt caccgtcgta cttttgtaat cgaagttatg
    10741 ggacgtaacg ctggtgatat cgctctttgg gctggtattg caactggtgc tgatgaaatc
    10801 atcatccctg aagcaggctt caagatggaa gatatcgtag caagcatcaa agctggttat
    10861 gaatgtggta aaaaacacaa tatcatcgtc ttagctgaag gtgtgatgtc agcggctgaa
    10921 tttggtcaaa aacttaaaga agctggagat acaagcgacc ttcgtgtaac agaacttgga
    10981 catattcaac gtggtggttc tccaactgcg cgtgaccgtg ttttggcgtc acgtatgggt
    11041 gcacatgctg ttaaacttct taaagaaggt atcggtggtg ttgcggttgg tattcgtaac
    11101 gaaaaaatgg ttgaaaatcc aattcttggt actgcagaag aaggggcatt gtttagcctt
    11161 actgcagaag gtaagattgt ggttaacaac ccgcacaaag ccgatattga gctatctagc
    11221 ttgaataaga gcttgtcata atttacaatt tagttaataa gaccaaaaag gtcatatata
    11281 taaaggagtc acaaaaatca tgaacaaacg tgtaaagatc gttgcaactt tgggtcctgc
    11341 ggtagaaatc cgtggtggta aaaaattcgg tgaggacgga tactggggtg aaaaacttga
    11401 tgttgaagct tcagctaaaa acattgctaa attgattgaa gctggtgcta acacattccg
    11461 attcaacttc tcacacggcg accaccaaga acaaggtgag cgtatggcaa ctgttaaact
    11521 tgcggaaaaa attgcaggta aaaaagttgg tttccttctt gatacaaaag gacctgaaat
    11581 ccgtacagaa ttgttcgaag gtgaagctaa agaatattca tacaaaactg gtgaaaaaat
    11641 tcgtgttgca actaaacaag gaatcaaatc aactcgtgaa gtgattgcgt tgaacgttgc
    11701 tggtgctctt gatatctatg atgatgttga agttggtcgt caagttttgg ttgacgatgg
    11761 taaacttggt cttcgtgtgg ttgctaaaga tgatgcaact cgtgaatttg aagttgaagt
    11821 tgaaaacgat ggtatcatcg ctaaacaaaa aggtgtgaac atccctaaca ctaaaattcc
    11881 tttcccagct cttgctgaac gcgataacga cgatatccgt ttcggtcttg aacaaggtat
    11941 caacttcatc gcaatttcat tcgtacgtac tgcaaaagat gtgaacgaag ttcgtgcaat
    12001 ctgtgaagaa actggaaacg gacatgttca attgttcgct aaaatcgaaa accaacaagg
    12061 tatcgataac ttagatgaaa tcatcgaagc agctgatggt attatgattg ctcgtggtga
    12121 tatgggtatc gaagtaccgt tcgaaatggt tccagtttat caaaaaatga ttatcaagaa
    12181 agtcaatgct gcaggtaaag ttgttatcac tgcaacaaac atgcttgaaa caatgactga
    12241 aaaaccacgt gcaactcgtt cagaagtatc agacgtattc aacgctgtta tcgacggaac
    12301 tgacgctaca atgttgtcag gcgagtctgc aaacggtaaa tacccactcg agtcagtaac
    12361 tacaatggct acaatcgaca agaacgctca agctcttctt aatgaatacg gacgtcttga
    12421 ttcagattca tttgagcgta actctaagac agaagtaatg gcttctgctg ttaaagatgc
    12481 tactagctca atggatatca aattggttgt aactcttact aagacaggtc atactgcacg
    12541 tttgatttct aaataccgtc caaatgctga catcttagca ttgacatttg acgaattgac
    12601 agaacgtggc ttgatgttga actggggtgt tatcccaatg ttgacagatg ctccatcttc
    12661 aactgacgat atgttcgaaa tcgctgaacg taaagcggta gaagcaggtc tcgttgagtc
    12721 aggcgatgat atcgttatcg ttgctggtgt gccagtagga gaagctgttc gcacaaacac
    12781 aatgcgtatc cgcacagtac gttaagaaaa atataaaaac ctatcatatc cagctttcta
    12841 gcctgtatga tgggctcttt ttttgtccag ggggcaaaaa gggggcaaaa ctttcataat
    12901 ggattgatac tcttcgaaaa tcaaattcaa accacgtcag cgtcgcctta ccgtatatat
    12961 gttactgact tcgtcagttc tatctacaac ctcaaagcag tgctttgagc aacctgcggc
    13021 tagcttccta gtttgctctt tgattttcat tgagtatgaa ataagatatg cataaattga
    13081 ttagaaagtc aaatgaattt ctacaaatgt tttagcaatc gcaatctact tgtctagatt
    13141 cgatctgata tattttcgat ttaatgatat ggtatttaaa acctccaaag tagcttgctc
    13201 cattctttta cctacgtgag tctagatgtt atttactgtt ttagcgtttt tgtgttctac
    13261 tctaaccatt atagcattct tctcagctag tgtactaagg agtgtgtgcc tgaaaatatg
    13321 ggaactaagg ggctggttta tcggtttctc tagtttagta tttgcctttt gcaaagtgat
    13381 cttaaatgcc tttctctaaa tttacatatc actattgttt aacaaaatct aatctatttt
    13441 aggtcactta ttcttttttt gaaatgtaga atgaactttt tcaaagtttt tcgaatcttt
    13501 taaaatctgt ttgttttata tcgccattct cccccttttt taattctccc tatatagcct
    13561 gacaactttt ccgatggtac gaatatggtt gctttcgtct aggtggatgt cggagtattc
    13621 gggattgagt ttttttgagg tagccttggc ggagtttctt gacatagtta gtgccgtcta
    13681 cttggaagat gccgatggta ttatagtcaa tctgtggggt attcttgata aataggtagt
    13741 cgctgtttct tatctttggc tccatggact tgctgacgac ataagcgatt gggtcgtagt
    13801 cgtctgggat aatggaaact ccataactaa atcgtcgtcc tgcatcaagc ggctacctgc
    13861 agagataaac tacctaacac gagagtaagt agtctgtctg tagtcgtcca gtctgatgat
    13921 ttttacgata cttcgttttt ctgatcatac agttgcctct cggcataggt cagaacttta
    13981 ccttgtctgg gtggtgcccg ttggtcgtag atagattgga tatcgctagg agaatccttt
    14041 tgaactggag gaaagagggc atcaatcaag ctactgaata ctttaactaa gtcaaatata
    14101 gtatttttct tagtagacct aacccttttt tcataatttc taatggtgtt tttacttata
    14161 cctatcttag tacccaattc ttattgagtc caaccattac tagtctatat tgttttatag
    14221 ttgattgagt ttggaatagt acgctgtagc tgctaaaaca tttctaggaa ttaatttgcc
    14281 tttcctaata gagttgttca tatcttattt caatctacta tatttttcac ctctaacaat
    14341 cgcaatctct tctttatcca tgaacgaaaa cgctttctat ctttgtaagt aaagcatcac
    14401 acgaaatcca cgaaaatgaa aacctttgtt gtgttttcgt aaaaaatttg ttgacagagc
    14461 acgaaacgcc tactataatt aaatcaagtt taaggaaata acaaaaaaac aaatcggagg
    14521 gaaagacgat gaacacatta aatgagaaag taatcaatat ctgtaaagca gtagttaaag
    14581 aaactttaat ccaagacatt taggagaaag aaatgaagaa atcaagaaaa ttagccacat
    14641 taggaatctg ttcagccttg tttttaggct tggctgcttg tcaacaacaa catgctactt
    14701 ctgaggggac gaatcaaagg caaagcagtt cagcgaaagt tccatggaaa gcttcataca
    14761 ccaacctaaa caaccaggta agtacagaag aggtcaaatc tctcttatca gctcacttgg
    14821 atccaaatag tgttgatgca ttttttaatc tcgttaatga ctataatacc attgtcggct
    14881 caactggctt atcaggagat ttcacttcct ttactcacac cgaatacgat gttgagaaaa
    14941 tcagtcatct ctggaatcaa aagaagggcg atttcgttgg gaccaactgc cgtatcaata
    15001 gttattgtct tttgaaaaat tcagtcacca ttccaaagct tgaaaagaat gaccagttgc
    15061 ttttcctaga taatgatgcg attgataaag gaaaggtctt tgattcacaa gataaggaag
    15121 agtttgatat tctattttcg agagttccaa ctgaggcaac tacagatgtc aaggttcacg
    15181 ctgaaaagat ggaaacattc ttctcacaat ttcaattcaa tgaaaaagct cgaatgctgt
    15241 ctgtagtctt gcacgacaat ctggatggcg agtatctgtt tgtaggccac gttggggtct
    15301 tagtacctgc tgatgacggt ttcttatttg tagagaaatt gactttcgaa gagccctacc
    15361 aagcgattaa atttgctagt aaggaagatt gctacaagta tttaggcacc aagtatgcgg
    15421 attatacagg cgagggactg gctaagcctt ttatcatgga taatgataag tgggttaaac
    15481 tttaatagtg ttatgatatg acagtaatct taggattttt atttctattt ttgatgagtt
    15541 ggtgggttat ttcaatcgtt aatagccaga aaccacgcaa aaatgaaaca tttattggct
    15601 atatccaaag atacgatatt gatgggaatg gctatcaatc attaccgtgt cctcagaact
    15661 gagaggagtt cttgaaatcg taaaactact ttgaacaaga gttacttcaa cccattggct
    15721 ccgacggatt aagttgcttt cgtgaacacc aaaatcagcc gcaatttctt cataagtgcg
    15781 gtattctcgc acatattgaa gagtggccat aagaaggtct tctaggctta atttaggttt
    15841 tcgtccccct tttgtgtgtt taagttgata agcagttttt aatacagcta acatctcttc
    15901 aaaagtggtg cgctgaacac caacaagaca tttaaatcgt gcatcagtta gttgcttact
    15961 tgcttcataa ttcatagaac tactatacca tattttgttt cgcaggaagt ctaatgctaa
    16021 aatcttatca gtgagaagat ttcttaaagt ttattctttg tagtttcatc tgtattagta
    16081 cataatttaa cttagagaaa ataggaggat taatcgaatg gaattaaaag attttacaga
    16141 aaaagaacag gaaatgatta agaaaaggct tacaatgtct aatattagtg acaaagaaac
    16201 tactgagaag attctggcgc tagtaccaca agacttgatt aagcgaatcc cgttttttgt
    16261 cagaaaacat gctacaacac gtacgattaa acgcatttca attgaacacc ctgaactcta
    16321 cgctgtagct caaacaagtg gtgagattcc agaaaaaaaa acgcgaagaa ttgcgtcaga
    16381 ttatcacaac tatctttgaa caaaagatga ataagcatag tattaagtag agaatgaaaa
    16441 aatattttat tggcggtttg ggaagcaatg cctatcatag caaggatttt ctttaagaac
    16501 tagattcgca ggtctatttt ctaaatccat atgaaaagca tcttcgagat gaaacagaat
    16561 tgaaatcatg gtttaaaaat gagattgtag aggaagaatc tatctgtctg ataggtcatt
    16621 ctattggagg cgatttagct cgttatttcg catcggaatt tgaagaagta aaga
//
LOCUS       DBERCW010000040        15118 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.040, whole genome shotgun sequence.
ACCESSION   DBERCW010000040 DBERCW010000000
VERSION     DBERCW010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.040"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            83..880
                     /locus_tag="ACL72M_001714"
     CDS             83..880
                     /locus_tag="ACL72M_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGS0716807.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="ACL72M_001715"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="ACL72M_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2383..3657
                     /locus_tag="ACL72M_001716"
     CDS             2383..3657
                     /locus_tag="ACL72M_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGS0716808.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELCLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="ACL72M_001717"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="ACL72M_001717"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGS0716809.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="ACL72M_001718"
     CDS             4786..5088
                     /locus_tag="ACL72M_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS0716810.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="ACL72M_001719"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="ACL72M_001719"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS0716811.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /gene="xseA"
                     /locus_tag="ACL72M_001720"
     CDS             5962..7302
                     /gene="xseA"
                     /locus_tag="ACL72M_001720"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGS0716812.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="ACL72M_001721"
     CDS             7280..7492
                     /locus_tag="ACL72M_001721"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGS0716813.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="ACL72M_001722"
     CDS             7489..8364
                     /locus_tag="ACL72M_001722"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGS0716814.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="ACL72M_001723"
     CDS             8357..9172
                     /locus_tag="ACL72M_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGS0716815.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="ACL72M_001724"
     CDS             9165..9596
                     /locus_tag="ACL72M_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0716816.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="ACL72M_001725"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="ACL72M_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGS0716817.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="ACL72M_001726"
     CDS             11272..12000
                     /locus_tag="ACL72M_001726"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0716818.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="ACL72M_001727"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="ACL72M_001727"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGS0716819.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13983..14180)
                     /locus_tag="ACL72M_001728"
     CDS             complement(13983..14180)
                     /locus_tag="ACL72M_001728"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716820.1"
                     /translation="MKIKEQTRKLAAGYSKHSFEVVDETDEVSSKHGFEIVDETDEVS
                     NHTYGKATLTWFEEIFEEYKN"
     gene            14360..14835
                     /locus_tag="ACL72M_001729"
                     /pseudo
     CDS             14360..14835
                     /locus_tag="ACL72M_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            14873..>15118
                     /locus_tag="ACL72M_001730"
     CDS             14873..>15118
                     /locus_tag="ACL72M_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGS0716821.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEARPILFRIPA"
BASE COUNT         4512 a         2735 c         3551 g         4320 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa acctcttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaagat gtcggttcaa tctttacctt
     2041 ccatgtcaaa ggtggcgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaact aaattcgttt
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttgcgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg cttcgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaaa gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gctgagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatgtttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataaggattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggccgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagccacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc agttgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagacttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gatcatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttt ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatcctac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattaactca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccattgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttacca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagattaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctttg
     7981 gaagaacttc agattattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ctgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtaatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggagag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gttagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcat cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agatttttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gaacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cattttagta
    10801 agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcgtcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatatttgt tcacgcaggt
    11701 attgatttga ctttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacaggg gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac gggaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagag cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga tctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaatcgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagtt ttgactacga attgtcagaa tatcgcccat ctaagctagt gaaaatggat
    13561 atccttctca acggagacaa ggtggatgcc ctcagcttta tcgttcataa ggactttgct
    13621 tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaggttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaatctcaa aaccatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac acaacaaaaa tataaaaaaa gagacaaaaa
    14281 agaacagaaa gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat
    14341 ggaaagaagg gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
    14401 cttagaagcg gataatcaag aataactctt tgatcaggta gcaagcttgt tggaggaacg
    14461 agaaattgta actccaactt atcgtgaagc tttgatcacg cgtgaaaagt catttccaac
    14521 tggtttagat atggaatttc taggaaagga cttgcaaatg taatgattcc tcacacagat
    14581 attgttcata atctagctga gaaagtggtg gttgttcgat tagagaaacc ggtgactttc
    14641 cataatatga ttgcgccagg taaggaagta gaagtatcct tgctcttctt tatcatcaat
    14701 aattcaagtt caagtcaaac gaacattctt gctcagttga tggacttttt cacaggaaat
    14761 ggacatcttg aagacctatc aaaaatttcc gaaccagaaa aactttatgc ttatatagat
    14821 gaagcaatcg cttaatcttg tctattaaaa aataaaatcg gaggaagtct atatgattaa
    14881 aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtgctctaga
    14941 agaagaactt tcaaaccgtg gttacgatgt tcactgtgat gcagttatgg tgaaagatgt
    15001 aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa cagaccttgg
    15061 ttttgaacca ggtatcccag ttatcgaagc taggccaatc ttattccgta tcccagca
//
LOCUS       DBERCW010000041        14812 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.041, whole genome shotgun sequence.
ACCESSION   DBERCW010000041 DBERCW010000000
VERSION     DBERCW010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14812
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.041"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(183..1805)
                     /gene="groL"
                     /locus_tag="ACL72M_001731"
     CDS             complement(183..1805)
                     /gene="groL"
                     /locus_tag="ACL72M_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGS0716822.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1821..2105)
                     /gene="groES"
                     /locus_tag="ACL72M_001732"
     CDS             complement(1821..2105)
                     /gene="groES"
                     /locus_tag="ACL72M_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGS0716823.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2261..2656)
                     /locus_tag="ACL72M_001733"
     CDS             complement(2261..2656)
                     /locus_tag="ACL72M_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGS0716824.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2734..3495)
                     /locus_tag="ACL72M_001734"
     CDS             complement(2734..3495)
                     /locus_tag="ACL72M_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS0716825.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3537..4163)
                     /gene="ytpR"
                     /locus_tag="ACL72M_001735"
     CDS             complement(3537..4163)
                     /gene="ytpR"
                     /locus_tag="ACL72M_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGS0716826.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4179..4496)
                     /locus_tag="ACL72M_001736"
     CDS             complement(4179..4496)
                     /locus_tag="ACL72M_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGS0716827.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4493..4792)
                     /locus_tag="ACL72M_001737"
     CDS             complement(4493..4792)
                     /locus_tag="ACL72M_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGS0716828.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(4990..5070)
                     /locus_tag="ACL72M_001738"
     CDS             complement(4990..5070)
                     /locus_tag="ACL72M_001738"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716829.1"
                     /translation="MASSGKMLRNTYTPDGYYVGNLGAWQ"
     gene            complement(5077..5268)
                     /locus_tag="ACL72M_001739"
     CDS             complement(5077..5268)
                     /locus_tag="ACL72M_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGS0716830.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5429..6103)
                     /locus_tag="ACL72M_001740"
     CDS             complement(5429..6103)
                     /locus_tag="ACL72M_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716831.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6109..6555)
                     /locus_tag="ACL72M_001741"
     CDS             complement(6109..6555)
                     /locus_tag="ACL72M_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0716832.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPCYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6669..7172)
                     /locus_tag="ACL72M_001742"
     CDS             complement(6669..7172)
                     /locus_tag="ACL72M_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS0716833.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7169..7531)
                     /locus_tag="ACL72M_001743"
     CDS             complement(7169..7531)
                     /locus_tag="ACL72M_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGS0716834.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7597..7710)
                     /locus_tag="ACL72M_001744"
     CDS             complement(7597..7710)
                     /locus_tag="ACL72M_001744"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HGS0716835.1"
                     /translation="MKDGNIIEQGNYEELMAQGGFYADLYNSQFTEDEAEE"
     gene            complement(7774..9498)
                     /locus_tag="ACL72M_001745"
                     /pseudo
     CDS             complement(7774..9498)
                     /locus_tag="ACL72M_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9473..9944)
                     /locus_tag="ACL72M_001746"
                     /pseudo
     CDS             complement(9473..9944)
                     /locus_tag="ACL72M_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(10068..10784)
                     /locus_tag="ACL72M_001747"
     CDS             complement(10068..10784)
                     /locus_tag="ACL72M_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0716836.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11665..13080)
                     /gene="ply"
                     /locus_tag="ACL72M_001748"
     CDS             complement(11665..13080)
                     /gene="ply"
                     /locus_tag="ACL72M_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGS0716837.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13091..13501)
                     /locus_tag="ACL72M_001749"
     CDS             complement(13091..13501)
                     /locus_tag="ACL72M_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716838.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTGIPTSYLARRRRN
                     VSEELYEEILDYLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(13494..14102)
                     /locus_tag="ACL72M_001750"
     CDS             complement(13494..14102)
                     /locus_tag="ACL72M_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716839.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14115..14573)
                     /locus_tag="ACL72M_001751"
     CDS             complement(14115..14573)
                     /locus_tag="ACL72M_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGS0716840.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14698..>14812
                     /locus_tag="ACL72M_001752"
     CDS             14698..>14812
                     /locus_tag="ACL72M_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS0716841.1"
                     /translation="MNYEASKQLTDARFKRLVSVQRTTFKEMLAVLKTAYQK"
BASE COUNT         4318 a         3425 c         2674 g         4395 t
ORIGIN      
        1 aactttgaaa acttcaaaaa acggattttt atcgccctga atatcaaaaa agaaaggacg
       61 aaatttgtcc tttctcgagc ttagctgact tcaacccact acagttgaca aagagcctat
      121 aaaaagaagg gttagtcatt ccctcctttt gtgtttttta taagttgttt tctatagaaa
      181 gcttacatca tcccgcccat catacttgga tccattgctg gagctggggc tactggttct
      241 ggtttattgg ctacgactgc ttctgttgtc aaaatcaagc tggctacaga tgctgcattt
      301 tgtagggctg aacgactcac tttaactgga tcaatgatac cttgatcaat catgttaacc
      361 cactcgccag ttgctgcgtt aaatcctata ccaagctcag catttttcaa acgatcgata
      421 acgatagatc cttcaaatcc tgcattgtga gcaatttgac gaacgggttc ttccaaagca
      481 cggagaacaa tattacgtcc tgttgcttca tctcctgtca attccaaggt agcaacagct
      541 ggaatcacat tggcaagagc tgttccaccg cctgcaacaa taccttcttc aacagctgca
      601 cgagtagcgt tgagggcatc ttcaatgcgg agtttcattt ctttcaactc agtttcagtt
      661 gcggctccga ccttaataac cgctacacca cctgacaatt tggccaagcg ttcttgcaat
      721 ttttcacggt caaattcaga agttgtagtt tcgatttgag acttgataac cgcaacacgg
      781 tgagaaatcg cttcaggatt tcctgcacct tctacaataa ccgtgctatc tttgtccacg
      841 gtcactctcg ctgcttgacc aagagcttca attgtcgcat ctttcaactc aagaccaagg
      901 tcttctgtga taactgttcc gcctgttaag atggcgatat cttcaagcat ggctttgcga
      961 cggtcaccaa aaccaggtgc cttgactgct actacgttga aggttccacg aatcttgttc
     1021 aaaacaagag ttggaagagc ctcgccatcc acatcatccg caataatcaa gagtggacga
     1081 ttgctttgga gaatgctttc caaaagtggc aagatctctt ggatattgga aattttcttg
     1141 tctgtaatca aaatgtacgg attttcaagg tcagccacca ttttttcgct atctgtcacc
     1201 atgtactgtg aaaggtaacc acggtcaaac tgcattcctt ctacgacttc aagctctgtt
     1261 tccataccac gtgactcttc gatggtgatg acaccgtctt tgccaacttt ttccattgct
     1321 tcagagatgt actcaccaac tttttcagaa cgagaagata cggctgcaac ttgagcgata
     1381 gcttctttat tggcaacagg gatggcgttg tttttcaaag cttcaactgc tgcggcaact
     1441 gctgtttcaa tcccacgacg aataccgatt ggatttgcac ctgctgtgac gtttttgatt
     1501 ccttcacgga cgatagcttg ggtcaagact gttgcagtcg tagtcccgtc acctgcgata
     1561 tcattggttt tagaagctac ttctgatacc aatttggcac ccatattttc aaaatggtct
     1621 tctaattcaa tttctttggc aatagtcaca ccgtcattgg taatcaatgg tgagccaaat
     1681 gatttttcaa gaacgacatt gcgacctttt ggtcccaagg ttactttaac agtatctgca
     1741 aggatatcga caccacggac catagctgaa cgggcatctg atgaaaattt aatttctttt
     1801 gacatactta ctttctcctt ctattcttca atgattgcca agatgttagc ttcgcctacg
     1861 atgatatact tttcatcgcc atctttgaca tcaagacctg cgtgggcttc aactaagaca
     1921 cggtctccag ttttaacact tggagcaacc aagtcaccgt tcaaggtacg aacaccttgt
     1981 ccagtagcca caacttgggc tgttttggtt ttttcttggg ctgaacctgc gagaacaaag
     2041 cctccaacag tttgttcttt ttcttctact tttaagacca aacggtcccc taatggtttc
     2101 aacatctgat ttcctccata atgagataga tattattagc actctttata cctgagtgct
     2161 aattcatagt tctattgtat cacttagtca gaaataatca agaaaaaagt ctgactttct
     2221 caagataaaa agcctgagac caactcagac tttttaattc ttaaaatggc aattcttcct
     2281 cttccaagac caaatctgcc aaatcttggc ctgcattatt ttcacgcata gcacgttggg
     2341 cacgactttc caagagttgg aatcctgtca caaggacttc ggttacataa ttcatctgac
     2401 catttttctc aaagcgacgg gtacgcaatt ctccatcaac ggaaatgaga ctacctttgg
     2461 ttgcgtagct tgccaaagtt tctgctagtc tgccccatag gaccatattg acaaaatcaa
     2521 cttcacgttc accgttttgg tctttgtaac gacggttgac agcgatagtt gctcgcgcta
     2581 ctgacttgtc attgttggtt ttgtgcaatt ctggtgtaga cgttaaacgt ccaatcaaga
     2641 taactttatt atacatattt tcttcctcct acttatctat tcgtaggaaa tcaaaaaaag
     2701 ttacagaaat ttgtaacttt tcgagaaaat tttttatttt ttatgaacca tgaaacctgt
     2761 cgcctgttga ttggccataa tggtcatatc tgtaatctga acacgacgag gttgactagt
     2821 cacatagact actgtatctg caatatcctg agcttgcaaa gcttctattc cttggtaaac
     2881 ggacgcagct cgttctttat caccatgaaa acgcactgta gaaaaatctg tttcgacaat
     2941 tccaggctga atggttgtca ccttgatatc cgttgcgatg gtatcaattc gcagtccatc
     3001 cgaaaaggtc ttaaccgcag ccttggtagc tgagtaaaca gcggcaccag cataggcgta
     3061 gattcctgcg gttgacccca tattgataat atgaccttga ttgactttta tcattgctgg
     3121 caagaaacag cgagtaaccg ccatcagacc tttaacattg gtatccaaca tggtcaacat
     3181 atccaactcc tcatagtctt gatagggagc caagtcaaga gccagtccgg cgttgttgac
     3241 caagatatca atcctcccta tcgtttctag aatatcagag caaacagtct tcaccatgac
     3301 catatccgtc acatctagtg gaaaagtcca gacggtttga tttggaaagc ttactgcaaa
     3361 ctccgacttg aggatttcta atctgtctat ccgtcgtcct gttagaacga catcctcacc
     3421 ctgctccaga taagcacgcg caatcgcttc accgattcct gaggttgctc ccgtaatcac
     3481 aacatttttt gccatcttat ttccttctag ctggtctatc agatattaac aacttcttag
     3541 gcagtccagt gtttagctga gtcaaatggt gttccgacaa cttggtcttc tgataattca
     3601 agcaccccac gtttttgtgg agcatttggc agatgcaatt cacgaggact gcacatcata
     3661 ccaaaactct tttcaccacg aagttcacct gggaaaatga gattcccttt tggcatcata
     3721 gctccaggaa gcgcgacaat ggttttcaac cccacacgcg cattgggagc tcctgcaacg
     3781 atttgtacag tcttatcact tgcgactgca acttggcaga tgttgaggtg gtcactatct
     3841 ggatgggcta ccatctcaac aatttcaccg acaacaaact taggttcctt atcattaaca
     3901 atttcttctg taaaaccttc cgcctgcaac tcttggttca aacgagcgac ttgctcatct
     3961 gtcaaaaaga cttgaccgcg ctctgcagtt tcaaataaac ttgaaacttc gaaaatattc
     4021 caagccactg tttccccatt ttctttgagg aaaacacggg ctaccttgcc tttgcgttcc
     4081 acattcagtt tggcatctcc gctatttttc acgatgacca taaggacatc accgacatgt
     4141 tctttgttat acgtaaaaat cattgtttcc tttttctcct atttcaatcc tgctaaaaaa
     4201 tcgttaattt gctccttact tttacggtcg cgattgacaa aacgaccgat ttccttgtcc
     4261 ttttctagaa caacaaggct aggaattccg taaacatccc agagtttggc caaatccata
     4321 tactgatctc ggtccattcg aataaaggtg aactctggat tggtctcttc aatctctggt
     4381 aaggcaggat aaatataacg acaatcgcca caccagtctg ccacaaaaag gaagaccttc
     4441 ttgcccgctt tttccactaa agatgctaat tcttctaaac ttgctggctg tatcataaga
     4501 cttcctcctc atagactagg tcttcatttt catagacaaa ggtataatga cggccatcct
     4561 caaaaatgac gccaccaacc aagctctcca gactgctttc gtaaacttga acataaaggg
     4621 tcgcaatttc ccccatgtcg gaaaaatggt ctcgcacaat ctctgtcaac tcttcctgag
     4681 tcttcatgag cttacggtca tctgcaactt ttttcgtagc aagggcaagg cttccgatac
     4741 ctagcagagc caagcctgcc atccacattt ttttagcttt cataccattc attttaacac
     4801 aaaaaaggct tcaggacaaa tgaggaagca gcagaaaagc aagtaaaaag cctcttcctt
     4861 taaggaaaag gacttcttat actaagagca aactagaaag ctagccgcag gctgctcaaa
     4921 acacggtttt gaggttgtag ataaggcgac gttgacgtgg tttgaagaga ttttcaaaga
     4981 gtattattct tattgccagg cacctaagtt gccaacgtag taaccatcag gtgtgtaggt
     5041 attgcgaagc atcttacctg atgaagccag ataatactac ttgccattgt ctttgaccca
     5101 atcattcgca atcatggaac cagaagaact tacataatac cattctccct tgtcataaac
     5161 ccaagtactg actttcatgg ttcctgagca attaaaggca aaaaaactgt ccaatatcat
     5221 tcgtttttta aaagcattcg acactacatc atctacgctg tagtacatag atacatcaaa
     5281 cgtaaaagcc aaaatatcga aaaatataca acttttaaag gcagcatttc attttttaaa
     5341 gtctaacaac catagaactg aaatcagagc aaggcatcaa tttcctactc tatagtacgc
     5401 ctattttgat ggttgaagtg aagatttttt atttaacgta gacaatttcc aacttcccaa
     5461 aagccacatc tccacggata atcaaggttt tgctggttgg ggctacagga gcgtcagcct
     5521 tagctgcacc aaaggaggtt tctactttca aatctacacg ccagtgttgt ggaacataga
     5581 cggttgcatt tccgaaggct acttcaatat ttaaagttgc aaaatcacct agcatctctg
     5641 cattatcata gtagatttta gcatccccaa aagcgacttc cacttggtca tctacgagat
     5701 cttgatcttg cttatagaag gtcccgctac caaaagcgac ttccttatcc gtgacgactg
     5761 tttttttccc attgtaccac catttttttt cattccagaa cttacttgaa tgcgtcagat
     5821 aaccaacacc aagtaccacc aagatgctag cccaaataag agaatgattg gtaactggta
     5881 acaagtcata agcgtaattt gcaatgatga gcgccagtaa acctgtaaaa actgccgaag
     5941 tgagatgacg tctaaggatg gactcaatgg acttataagc aaaaaaaaca atacctagta
     6001 aaggccatat tttaccatcc aaagaaggaa ttccaaaatt cccttgcagc aagatccaag
     6061 ctgctaaaac caataaaaca ataccaaatg ctttcttttt catgtttttt acctcatgtt
     6121 tcttagattt tcttttagga gggattggta atgccgtgag acatgaacct ccttgtgcgt
     6181 ctgataaaag gaaatggtgc ccgttcctga aaaggacttg tccactgagt aaatctgacg
     6241 gatgtttgcg atcgttgact tggaaactcg attaaaatag caaggcaaga tagactccaa
     6301 ctcatagagc ttgaggcgaa cctcataagc ttccttctgg ttatgagcgt agatcttgct
     6361 cccttctgtt tcaaagaaga gaatttctga caggtctaga taatattcac ctgtcccctt
     6421 gtaaaaagtc aacctcggag cctttgactc ttgcaagagc cgttgcaagt ctgcaatttc
     6481 atctgtcaaa gtgggggtct tgatgacaat ttcagtctcc tctaaattgc cgtcaatctc
     6541 aattcgtaac ttcatcacat ctcctttctg actctactat atcaaagcta agttaggaat
     6601 acaagggcaa aaaagcaagt ggtcaatttg aagcagtaag tggttgtagg actagcttaa
     6661 cttacatgtc agaataggaa gaaaaggaat ccccacacca aaccacaagc atagccaacc
     6721 aagacatcct tgggataatg aacaccccct aaaaccctca ccaaccccag caaagctgaa
     6781 aagatcaagc atactaagcc aataggtaga ctagcatgca gacaggccat ggagatgata
     6841 gttgccgaaa agacatggcg actgggcatc gaccgtcccg aactatcctt atcaagaagg
     6901 ggacagatat cccaagtttc ataaggtctc gggtgattga ttttcttacg aaacagggac
     6961 aaggtcacaa aacctgatgc aggaataagc acataaaccc caacttgctg accaagtcct
     7021 agttgcaggt aagtggtgac tagcaagatc agatagacca ggggcatggc gactgtcatc
     7081 aaacgattga aactgcgtaa taggaataaa agaattggac gactagttag tctggagctg
     7141 atatttcgat accattcttg ataatttttc atttatgctt ctcatacttt tctagaactt
     7201 gttgagatgt tttccccttg gcaagccaat ccactagctt gtccaagcga cgtatttcct
     7261 gcatcagagg atcatcaatt tcctcaatac ggacaccgca aatcttccct gtaattgcaa
     7321 ttcgttcagg gacataatat ggtgcttgtc taaaaaaatc tccgtaagta acatccctat
     7381 ccagacaagc aagaacatca ctcacttcat accctgtcaa ccaactggtc acttggtgaa
     7441 ctgactctgc ctttccaccc tttcgctcaa cttttgcaat caaggctaag tagacagcag
     7501 caaatttcat attgtataat ttctgactca tacttctctc tttctatgtg tactagtata
     7561 aataagaaaa agaaggccgt caagccttct tttgatttat tcttctgctt catcttctgt
     7621 aaattgacta ttgtacaagt cagcgtagaa gccaccttgc gccatcagtt cctcatagtt
     7681 gccttgctcg atgatatttc catctttcat gaccaagatc aagtctgcat ttcggatggt
     7741 tgacaagcgg tgggcaatga caaaggatgt gcgtcattcc atcaaacggt ccatggcttt
     7801 ttggatcaat tcctctgtcc gtgtgtcaac agaagaagtc gcctcatcca aaatcaaaag
     7861 cggtgcatcc ttaagaaggg cacgagcaat agtcaatagt tgtttttgtc ctacagacaa
     7921 ggtcacggtg tcatccaaga tggtatcata gccatctggc aaggtcataa taaagtggtg
     7981 aattcccaca gccttactag cttccatcat tcgttcatca ctaatcccta tttgattata
     8041 gatgagattg tctcgaatag ttccttcaaa gagccaggta tcctgcaaga ccattgaaaa
     8101 ggcatcatgc acttctgaac gcgtcatagc cttggtatcc acaccatcaa tgtgaatact
     8161 tcccttatca atctcataga atttcatcaa aagattgaca atggttgtct taccagtccc
     8221 agtcggccca acaatggcaa ccttttgacc agcatgagct gtcgcagaga agtcatagtc
     8281 ttgaacattg acaccgtcca ccagaatttc tcctgctgac acgtcgtaga aacgtggaat
     8341 cagattgacc agagttgatt taccagaacc tgttgaccca ataaaggcca ctgtttgacc
     8401 agtttctgct ttaaagctaa catgttcaat aactgcctcc gaatttgccg catagcggaa
     8461 ggtcacatcc ttaaactcga cctgaccttt gaagttttca tcagtcagct gcacttgaac
     8521 agggttttgg atagaagaat gcaaatctaa aacttgatta atccgcttag cagagaccat
     8581 agttcgggga agaacgatga agagtgctcc catgagaagg aagcccatga caacctacat
     8641 ggcataagac atgaaaacaa tcatgtcact aaagagaggc agacgcgcta tcgaagcagc
     8701 gtcgttaatc acataggccc caatccagta aatcgctaca ctcaaaccac ttgaaatccc
     8761 catcatgata ggattcaaaa tagccataag acggttgaca aacaaattca aacgggtcaa
     8821 ttcatcattt actgctgcaa atttttcatt ttgataatcc tctgcattgt aggcacgaac
     8881 gacacgaata cctgttaaac tctcacgagt gatactgttc agtttatctg tcaacccctg
     8941 aatcaaggac tgttttggaa aggctagcgt catcaaaacg gtcgtcatca ggacgttgac
     9001 aatcactacc acaagtacgg cccagagtca gtattctgaa tgacctaaaa tcttcccaat
     9061 agcccagata gccataattg gaccacgcgt taccacttgc aagcccatag taatcaacat
     9121 ttgaacttga gtaatgtcat tggtagtacg cgtcaagagg ctaggaattg aaaatttctt
     9181 aatctctgtc tgcgagtaat ccaaaactcg gttaaaaata tcacttctca gcctactagt
     9241 ataagaagcc gccactcggg atgcaaaaaa tccaactgca actacggaca agaaggcaag
     9301 aaagagcatt cccatcatca tgcttgccgg ctgccacaac tcatctaaat tagtttcttg
     9361 actacctagc aaatccgtaa ttttcgagat ataggtcggc acttccaact ctagatagac
     9421 cgaaaagcaa gtaaagaaaa tggctagtaa aatcatcccc cattcttttc tactaattct
     9481 tttggttaat ttctttattc tctcctccta ttcccttgat attttgcctg tagttgaccg
     9541 agaactttct caaaaatcag taattcatct tcatcaatgt cttccatcaa ctgcttgtct
     9601 atgcgttcaa aaaaagcctt aacctgttgc atctgagaac gtgctttgtc cgtcagacga
     9661 acaaacttag cccgcttatc aacaggactc gcctccaatt ccaccaaacc attttgcact
     9721 atacgcttaa ccagattact agcaacagac ttggtaatat tgagttcctg ctcgatatct
     9781 ttaatcaaga ccaagtcttg gtttttctag cgattatcca aaaaacgcac aacctgacct
     9841 tgcggcccac ccataaattc aatgccgcaa cgtttggctt ccttttgcac catcaggtga
     9901 atttgatgac caaaacgctt aaagactaac atcggtttat ccataatctc ccccttctaa
     9961 ataaaaatag ttctctggag aataattaaa tttctatgag aactattttc ttgattaaaa
    10021 aaatcccaag tgattttctc acttaggatc atgttctata ggttaaatta aaacccatct
    10081 acgttcgtat aaatcttttg gacgtcttcg tcgtcttcaa gaacgctgta aagtttttca
    10141 aaggtttcaa ggtcttcgcc tgacaattcc acttctgact gaggaatcat ttccaattca
    10201 gtcacttgga attcttcaat accagactca cggagagcaa cgatagcctt gtgaaggtca
    10261 gttggcgctg tgtaaactgt gattgtacct tcttgtgctt ctacgtcatc cacatccaca
    10321 tccgcttcga gcaattgctc aaagactgcg tctgcatctt cacctccaaa tacaataaca
    10381 cctttgttgt caaagaggta agaaacagaa cctgaagcgc ccatgtttcc gccgttttta
    10441 ccaaaggctg cacggacatt ggctgctgta cggttgacgt tagaagtcaa agtatccaca
    10501 attagcatag agccatttgg cccaaaacct tcgtaacgtc cttctgtaaa ggtttcgtct
    10561 gtgtttcctt tggctttatc aatcgcttta tcgataatgt gttttggcac ttgggcttgt
    10621 ttagcacggt cgataacgaa tttcaaagct gagtttgatt ctggatctgg atcacctttt
    10681 ttagctgcta catagatttc tacaccaaat tttgcatata ccttagagtt agctccatct
    10741 ttagccgttt tcttggctac gatattggcc catttacgtc ccattaggaa tctccttttt
    10801 tcacatttta atctttatta ttataacaca agtttttttg attttcacta gaggaaatgg
    10861 attttattag caaatcaagc taggatagca ctttacctgc taagatggtc ttacctttct
    10921 atctttatca acagacactc atccacattc aaaaaacaaa ctagaccatt atctgcaaat
    10981 agaaagtttc agccaagttt gacaaagtca gctcaaatta ctgtttgaag tttgtagata
    11041 taagcgacaa aaacaatcat actgcacctt ttgttgacag tctactccag acatatcata
    11101 gttcaagtaa atactttgaa attcaacagt tcttataggc gctattgtat tctaagaaat
    11161 caatagaaga gtttctaagc aaacctctaa tactcaataa aaatcaaaga gcaaaccaga
    11221 aagctagccg caggttgctc aaaacactgt tttgaggttg cggatggggc tgacatggtt
    11281 tgaagagatt ttcgaagagt ataatttacg tgttcccaag atggagaagt tagactagta
    11341 cactggcact tctaaaccat tgctagcaat tgatttgttc atatttaatt tcattttttc
    11401 cataaatggg tattagatat aaacagcaaa atatttccga tacgtgtcgt tcttgaattt
    11461 ccaatcatct aaaacaagta aaggataatc aatcccctgt atatcaagga attggctacc
    11521 ctttttactt ttttacacat tctgtttgat agattcattt taacatcacg agcatactcc
    11581 aatggaaatc gctaggcaag agataaactt tcagatatcc gcagagagat catcgcctct
    11641 ttttgtcgca agcattctcc tctcctagtc attttctacc ttatcttcta cctgaggata
    11701 gagagttgtt ccccaaatag aaatcgtccg cttacgcact agtggcaaat cggttttttc
    11761 ataaaccgta cgccaccatt cccaggcaag cccggtacac tctctaattt tgacagagag
    11821 attacgaaca ttccctttta aaggaatact agtggtaaag tgagccgtta aatcctgccc
    11881 atttctgtcc caagccttag gagtcaagac ttccttacct tgatgatcat aggataattc
    11941 attccaagta atataatatt gggcaacata ggcaccacta tgatccagca gtaaatctcc
    12001 gtttctgtaa gctgtaacct tagtctcaac atagtctgta ctattttgaa aggtcgcaac
    12061 tacattgtca cgtaaaaaag aagttgtata ggaaatcggc aagcctggat gatctgctgt
    12121 aaagcgactg ccttcttgaa tcaagtcctc taccatatcc accttgcctg ttacaactcg
    12181 ggcacccgaa cttgggtcgc cccctaaaat aaccgccttc acttctgtat tgtccaaaat
    12241 ctgtttccac tctgtctgag gagctacctt gactcctttt atcaaagctt caaaagcagc
    12301 ctctacttca tcactcttac tcgtggtttc caacttgaga tagacttggc gcccataagc
    12361 aacactcgaa atatagacca aaggacgctc tgcagaaatt cctctctgtt ttaaatcctc
    12421 taccgttaca gtatcttgaa acacatctcc tggattttta acagcatcta cgctgactgt
    12481 ataataaatc tgcttaaaat taacaatctg aatctgcttt tcgcccgaat ggacagagtt
    12541 aaaatcaata tcaagagaat tccctgtctt ttcaaagtca gaaccaaact tgaccttgag
    12601 ttgttccatg ctgtgagccg tgattttttc atactgcatt ctagctggga cattattgac
    12661 ctgaccataa tcttgatgcc acttagccaa caaatcgttt accgctccgc gaacacttga
    12721 attgctgggg tcttccactt ggagaaagct atcgctactt gccaaaccag gcaaatcaat
    12781 actataagtc atcggagcac gatcgaccgc aagaagagtg ggattattct ctaacaaggt
    12841 ctcatccact acgagaagtg ctccaggata gaggcgactg tcgttggtag ctgttacaga
    12901 aatatcactt gtatttgtcg acaagctccg cttctttctt tcgataacaa caaactcatc
    12961 gggtagctga ttaccctctt tgatgaaacg attttcaata ctttctccct gatgggtcaa
    13021 gagtttcttt ttatcgtaat tcatagctag tataaagtca tttactgctt tatttgccat
    13081 cttctacctc ctaataagtt cctggattga gttgcataaa ctcagacttg ttcagcgaaa
    13141 tcagccgtgg ttggactaag taatccaaaa tttcctcgta caattcttct gagacattgc
    13201 gtcgccgtct ggctagataa gaagtcggaa tgcccgtatt atccaacata aataccttat
    13261 ctaagtcaat caaggttggt cttgtaaaag gattacgagc tagatccggc tcttctatca
    13321 taaagttctt gaccaaacgt ctggtcaaga gagctggttt gaaggtctga tttttaacca
    13381 actctttgtt tttagtcatg ctgttgtcaa tacagatata catatgattc ttcacagcca
    13441 aatcgctact aatagtcgga aaaggcaaat aaagagctac aacatctcct ctcttaatca
    13501 agcaagagca cccccttttc tcctaatgta acatagacag gattgaccaa gtcttctgat
    13561 tgactcagaa tttccaaagt ttgagtttgg cgcgctgtca atttagtagc atcttgtctc
    13621 ttcaatacaa aatgcttgtc gccaataacc ttgacaatat aatccttctc caaagctgac
    13681 tggtaaatcc acatcagatg ttgtctgtcc tgagaactca agagagaagg attttcaagc
    13741 ctcccgatag tctgataaaa atcaaaaaca ggagctaact cctgccaatc tgattggcta
    13801 gttgtcaagg ctagaaaaag ggctttgcga gctgatactt cttggttagc cttgagagtt
    13861 actttcccct ccaagttttt tagaaatcgg gaaactccag aaagcaaatt tttctctaac
    13921 tgcgagaaat aaaaaccttt cgttcccaga cataagtctt tcatgtcgct ttctctagca
    13981 aataagagct caaacatttg atagtaaaag aaaaatatct ggcactgggt cgcgctcatc
    14041 ttttccttat cggcttcttt ttttaaccag agcaagggcg acaggtaact ggattgagac
    14101 atttcctcta cctcctactc ttttttaact ggagcatctg cactagctgc cacttctttt
    14161 gactggatac tttcccactg gttaatctcc tctgagataa gaccttcgca tgtcttgaca
    14221 aatagggcaa aagccttggt ctttcctgca tatttctccg tttggcattg atagaggaat
    14281 ttttctttct ccaggagttg cgcagttttt tggtaagaaa tccaattttc ctttgcatta
    14341 tacaaattga taatcccctc acacagcaag ccgagactgg ataaggcaac cgaaatcaaa
    14401 cggtagcgat cacctggcat aggaatagca caaaagacag ctatgaggaa acctgccacg
    14461 atttctgtta tttttaatac cttatagcgc ctacgatgtt gaacgctttt ctttaaaaaa
    14521 tgagctatct gtacgtctaa tcgctctgtc aggtacattt cttctggcgt catattcgta
    14581 actcctttca tttactttga taaccatagt ataacatatt tgaatatcaa agtatagtaa
    14641 aaactggact ataacttatt agacttcctg cgaaacaaaa tatggtatag tagttctatg
    14701 aattatgaag caagtaaaca actaactgat gcacgattta agcgtcttgt tagtgttcag
    14761 cgtaccactt ttaaagagat gttagctgta ttaaaaacag cttatcaaaa aa
//
LOCUS       DBERCW010000042        14639 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.042, whole genome shotgun sequence.
ACCESSION   DBERCW010000042 DBERCW010000000
VERSION     DBERCW010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.042"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            35..491
                     /locus_tag="ACL72M_001753"
                     /pseudo
     CDS             35..491
                     /locus_tag="ACL72M_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            656..955
                     /locus_tag="ACL72M_001754"
     CDS             656..955
                     /locus_tag="ACL72M_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGS0716842.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="ACL72M_001755"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="ACL72M_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0716843.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
     gene            complement(2268..3995)
                     /gene="ezrA"
                     /locus_tag="ACL72M_001756"
     CDS             complement(2268..3995)
                     /gene="ezrA"
                     /locus_tag="ACL72M_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGS0716844.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4077..6023)
                     /gene="gyrB"
                     /locus_tag="ACL72M_001757"
     CDS             complement(4077..6023)
                     /gene="gyrB"
                     /locus_tag="ACL72M_001757"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGS0716845.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6038..6601)
                     /locus_tag="ACL72M_001758"
     CDS             complement(6038..6601)
                     /locus_tag="ACL72M_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0716846.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6686..7240)
                     /locus_tag="ACL72M_001759"
     CDS             complement(6686..7240)
                     /locus_tag="ACL72M_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGS0716847.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(7251..8474)
                     /locus_tag="ACL72M_001760"
     CDS             complement(7251..8474)
                     /locus_tag="ACL72M_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS0716848.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8511..10961)
                     /locus_tag="ACL72M_001761"
     CDS             complement(8511..10961)
                     /locus_tag="ACL72M_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGS0716849.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPFSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11161..12090)
                     /locus_tag="ACL72M_001762"
     CDS             complement(11161..12090)
                     /locus_tag="ACL72M_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGS0716850.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            12230..12517
                     /locus_tag="ACL72M_001763"
     CDS             12230..12517
                     /locus_tag="ACL72M_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGS0716851.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12551..13885)
                     /gene="ciaH"
                     /locus_tag="ACL72M_001764"
     CDS             complement(12551..13885)
                     /gene="ciaH"
                     /locus_tag="ACL72M_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGS0716852.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13875..14549)
                     /gene="ciaR"
                     /locus_tag="ACL72M_001765"
     CDS             complement(13875..14549)
                     /gene="ciaR"
                     /locus_tag="ACL72M_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGS0716853.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         4506 a         3082 c         2600 g         4451 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggagt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat tcaaaccaca tcagcgtcgc cttaccatac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttt attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag gcctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcggag
     1201 gaaaagtatt gtactatgat gattcaacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgataca aggaatcgat tcactggctt atctcgttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggatactat ataaacgctt tgagaacgga
     1441 aaactgactt ggcccagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacccctact tctaaaacat tgttagaaat cgatttgact gtcctgatca atttgtcctg
     1621 ttcttgtttc attttactat agaacgattt gaaggcgttt atgatattta gctgtacgag
     1681 agtcttttaa aagtgttttg atggtttgga tttcttcttt agttgatttt atattactat
     1741 tatataatga ttttttattt tagtctagta taaatagcga gaaatatcta tcctatcttc
     1801 tagaatgtct tccaaacgag aaaactctcg taaacaaaga ggttttagag gcctatttac
     1861 cgtggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta ggaactatcc
     1921 gtgagttctc tagtctggag atttttcaat agacttcgtt attggacggt taccaagtta
     1981 ctcaaagtac agatttgaag ctgcagataa gactgacgaa atcactttaa tactaaatga
     2041 aaatcaaaaa gcaaactaag aagctagcct caggctgtac ttgagtacgg taaggcgacg
     2101 ctgacgtgat ttgaagagat tttcgaagag tataaaacac tgttttgagg tggtggataa
     2161 atcggctggg taaaaactca atctcaggag aaaatgaagt aaatctcccc acaactatag
     2221 aaaaagattt gattctgctc ctcacacaat aaaatctttt tcttttatta aaaacgaatc
     2281 gtttcacgtg ttttctcata tgaggtaaca aagcgattgg ttacaccagg ctctgccact
     2341 tccaatgctt gagaaatctt gtcaaatgaa gcgtgataat caaattcttt ttcaaaaata
     2401 tctaaagctt cgttaaatgc ttcttgaatg cgttcatcaa atgagcgata gcggttagaa
     2461 tattgcaaga gttgctctgt caaagttgca tattgtacaa tattataagt ttccgtttct
     2521 aaagcttcca tatcattcgt tgcaatttca agaactcggg taacagattc aatgttaatc
     2581 attttttgtt ctaactcaac cattaaatcc tcggtattat tgcttgccgt aaagaataac
     2641 ttcaagaaag tttgtggaat acctggcaga ttgcgttttt ccatgtatcg cttgatagta
     2701 tggagacgat tgacataaac attggccttt tgacgtgcat taatatcatc tttctcaatt
     2761 tgtgtcaggc gctcactaac tgaaatttgc tcatcttcaa tatcttttag ttgagtttgt
     2821 aaatcctcaa gattttcttc aagaactgaa taagcttggg ttggttcttc ttgatttgaa
     2881 gttacctcaa caatagctgc ctcaaaactc tctaattctg tctgaatacg acgaacatgg
     2941 cttgcagctg tctcaggaag taaataggtc ttgttcaaac gtgcaatatc ttctcccaat
     3001 aaagtattat tctctttcat atgttgaagg taagttggaa gagttgcaag tagattttcc
     3061 actactttct gagcagcaat ttctcgagta aaaatatcat acaaggcatt gatttcctct
     3121 tgtgcctgtc cattctcata ttcggcatta tccaattcca actgacgaat attctcttgg
     3181 tttttcttga atgcttcata aagcaagtgg aaacgcgctt caatatccgt ttcaacaaaa
     3241 tgataattag catcaattag tttacgataa ccggattcca aatcctgtaa ttgatctggc
     3301 aattctgtag aaagcgtcgt aaccaaggct ggaacacgat ccacaatatg acttaaggcc
     3361 aaaatgtgat tttctgtatt atccaaaatc actgcggctt ccacagggtc acccgatgaa
     3421 ttcaaggtta caaattgtga aaattcagat tggatatttt ctaattgttt ttcaatttca
     3481 tccaaggctt gaccatactg ttctgaattt tcagcaactc tatgctgaag ttcctcaaat
     3541 aaatccaaag catgaagaac acgaccacta tttttagatt cttgcttctc taagtctgcc
     3601 aaagcattgc gaattgccgc aatatcttcg tcaatcaaag taatttgact ctcaatttgg
     3661 tcaatttgat gactggcctt gagaaaacga aatgaatggt tatagccttc tgcttcaaag
     3721 agattatttt caatatcggc aaaagagttg agagataaat cgacccattt ttgattccat
     3781 tcacggaaag ccacttgact ttgtccaatc aagtgcatat tttttacagc ttctacttca
     3841 tcatttactg gaagattgta tagttcttct tttctttctt ctagcgcctc taatctcccc
     3901 tcgtttcgct tacgtagaaa gattgccact acataagcca gaactaaaat gactgcaatt
     3961 gcaaccatta aataaattag ttgtccatta gacatatcaa actccttttt tacttgaaac
     4021 aatcgtaacg attatatcat attttttaga ccaagggaac tacttctccc tattttttag
     4081 acatcaagtg tactatagac agcattttct tcgataaact cacgacgagg ctctactcga
     4141 tcccccatca acatatcaaa gattttatct gcttctgcag catcatctac agaaactcta
     4201 gccatcaagc gatgttcggg atccatggtt gtttcccaca gctgatgatc gtccatttca
     4261 cctagcccct tataacgctg aatagtcggt ttggtacgac cttcactata acgggctaaa
     4321 gcttcttgga gtttgatttc ttgatctgca cccggctgga tatattcttt aatctcgctt
     4381 ccaaccttga caccatagat tggtggttgg gcaatataaa cataaccagc ttctaggatt
     4441 ggtttcatat aacgataaat caaggttaaa agaagggtac gaatgtgggc tccatcgaca
     4501 tcggcatcgg tcatcaaaac gagtttttgg taacgggctt tcgaaacatc aaattctgcg
     4561 ccaaatcctg ttcccatggc tgtgaaaaga ctacgaattt cttcgttagc tagaatctta
     4621 tccatacttg ctttttcaac gttcaaaatc ttaccgcgaa ttggaaggat agcctgaaac
     4681 tcacggttac gaccagattt ggctgatcca ccagctgagt ctccttcgac gatgaagagt
     4741 tctgtttcag cagggttatt agaagaacag tctgctagtt tccctggaag gttggaaatt
     4801 tccaaaccag attttttacg tgtgacttca cgcgcacgct tggcagccac acgagccttg
     4861 gcagctaaaa tccctttttc cacgatacgt ttggcaatct gtggattttc catgaggaaa
     4921 tcggagaagg cttcactgaa gaggcgattg gtaatcttga ccacttcgct atttcccaat
     4981 ttggtcttgg tttgtccttc aaactgtgga tttgggtgtt taactgagat aactgcagtt
     5041 aatccttcgc gaacatcttc ccctgttaaa ttatcttcat tgtctttcag taacttattc
     5101 ttacgagcat aatcattgat aacacgagtc agtgccgtac ggaaaccttg ttcatgcgtt
     5161 ccaccttcat gggtatgaat attattggcg aaactcatga cattttcatg gtaacctgtt
     5221 gtgtactgca tggctacctc aactgtgata tcatccatct caccgtctgt atagattggt
     5281 gtatcaaaga ttacatcctt gttctcgttg atatattcaa cgtaactagc aatcccacct
     5341 tcataatgat aatgcttggt ttgttccaaa ccttggcgct tatctgtaat tgaaatttga
     5401 agaccgcgat ttagaaaggc caactcttga atccgtttat ttaatttatc aaaatcaaag
     5461 attgttgttt cagtgaaaat ttctgggtcc ggtgtgaagt gaaccgttgt tccagttcta
     5521 tctgtatccc caaccacctc aaggtctgca acaacatgac cacgacggta ttcttggtaa
     5581 tgaatcttac cgtttttatg gacatgaacg tctaattgag tggaaagggc attaactact
     5641 gacgacccca ccccgtgaag accacctgaa accttgtatc caccaccgcc gaactttcct
     5701 ccagcatgaa ggactgtaaa gacggtctca acagcaggac ggcctgtttt ttcctgaata
     5761 tcgactggga taccacgccc atcatccaca acagtaatcg aatcatctgg ctcaataaaa
     5821 acttgaatat ggctggcaaa tcctgccaag gcctcgtcaa ttgagttatc aacaatttcc
     5881 cagactagat ggtgaagacc ttcttttgag gttgatccaa tgtacatccc tggacgcata
     5941 cgaacagcct ctaagccctc taaaacttga atttgactgg catcataatc ctgtgcctgc
     6001 agatttttga tttcttctgt catcttattc ctttttctta tatgtctaat acttgtctta
     6061 aattcacgat actggtaaac aagtgggtat caagtcctgc agcttgacct gcttcgatat
     6121 caatcggccg atcaccaatg acaagaccag agctaatctg atacttttct cttaaataaa
     6181 gcatggattc gggatttggc tttctcttaa agcctgagct agaagtcacc acttctgtaa
     6241 aataagctgc tatagaggtt ttttctaaaa tttccaaaac ctgatcattt cgatgagaga
     6301 ccaaaaaatg acggccacct tgatttaaaa tgtcttccaa taggtcagaa actccttcaa
     6361 ataaaatcgg gtgttcaagc tctctggctt cattttcctt gtacttttct aaaaaattct
     6421 ctaaattggg agcgaatgtc tcaatcgcaa aaggagtaga aacctttaaa gcttgataga
     6481 cactgtcatg gtcttgtgtg ataccataca gtgccaatgt ttcaacaaat gcagctgttg
     6541 aagtttcata attatccagt aaagttccac ctaaatccca gatgtaatcg tgatatttca
     6601 tacccttcat tatagcattt ttttatgaaa aaagcgatga tttccctgag ttttccacat
     6661 aaaaaacgag agaataactc ccgttttact gatttttacc aaagacatct cgatagagca
     6721 ttcctgttcg taaactctct gcgtcccctc ctagttgctc caccaactcg taggcaaagg
     6781 caagggctgt tgaaggaccc cgactggttg tcaactgacc atctaccact actgtttcct
     6841 tgacgtagtg accatcaagg atttgctctt gaacgccgtc ataacaagtg tatcgcttat
     6901 ttttcaatat ctctgcttga ttgagggcaa ttggtgccgc acaaatggct gctagtttct
     6961 tcccttcttg ctcgaagctt tgcaattctt gaatcaaggt ctgattatca cgtaaatgtg
     7021 cagaaccagg catacctcca ggaagaacaa tcatatcata gtctgataaa tctccatcaa
     7081 agacatgatc tgctcttact tggattgcat gcgaacccgt tacttgctct tcaaaaccaa
     7141 ccatatcaca tgtgatattg gctcgacgca agacatctac aactgtcaag gcttcaattt
     7201 cttcaaagcc ctgagctaac ataactgcta cttttaccat gattttctcc ttatttaatt
     7261 tgttttaata caaccttttt ccgtttgaat gggacttttc cgctcttttc ttcagctaaa
     7321 ttagtctggt aactcatcga taaaagcaaa ccaacaccaa tcaaattact gataatagct
     7381 gatccccctt gcgaaatgaa aggcaaggga atccccgtca aaggaagtag tccagtcaca
     7441 gcaccgatat tctcaaagat gtggaagagc aacatcataa tcaaacctgt ggaaatataa
     7501 gtgtagaact ggttatttga tttaagagta atcttcaaca tacggtaaat caacatgaga
     7561 tagagggcaa taaccaggac agagccaata aagccaaaat cttctgcaat aaccgtaaaa
     7621 atcatatctg actctcgaac tgggataagc agattcgaag cattaaatcc ctgaccaaat
     7681 aagccaccac tcccaatggc aatctgccct tgagcctgct ggtaagtcgt tgtttgggca
     7741 aactcaaagg gattgagcca agccaaaatc cgattaattt ggtaggtcgg cattccaatc
     7801 tggtgaagaa aagctcgtcc gtccttgcta ataaagatag ctaagaaacc agcaactcct
     7861 gttacagcag tcacaaatac tgggataata attttccaag aaacccctga taataaaacg
     7921 attcctgaga aaatggctac aaaaaccaaa gccgtcccca agtcactttg aagtgctaaa
     7981 agaactagga ctggaatggt aaagagaatc atccagaaaa ttaacaaaaa gtccagcgga
     8041 accgtgcgtc tccattcctt atgtttcttt gtaaattgga caatgacacg agccaacatg
     8101 aggatatagg atatcttcat aaattctgac ggttgaaata gggtaattcc atttattgat
     8161 acccagtttt tggcacccgt tgatgcaact aagcttggat tataaaatac aatcggcaag
     8221 atcataagtc ccaagcctaa aatatataga aagggggtca ccttccaaag aaattctgta
     8281 ttaaagagca tgaccacaaa accaatcaca agccccaagg caatccaggc gacctgctgc
     8341 cctaaaatgg gcagaatatt attgggataa tcatgactaa cggctatata gatagccacc
     8401 acaccgatga ccagtagaaa aaatactggc aagagcaaac tataatcgac tctagagtcg
     8461 agagaacgtt tcatatgtac taaccttata ctttcataca atactattta tcaaagttca
     8521 ttaaaaaatc tatcaatagc ctcgtcaact tcggatcgag agatggtttt aacagtcgct
     8581 tcttctgcta gagatgctac tatttgtttg ccgtatcgtt ttccgacgat tctcctatcc
     8641 aaaataagag ttaaggaacg ttggtattca cgtctcatac ttcttcccaa agcctgtttt
     8701 aaacgaataa tggccattgg caattgataa tcataaaagg catttttccc ttcttgattc
     8761 agttcttgat taatcttttt cgtcaagggt tcttgaggat tttggaaagg aagcctcggt
     8821 acaacttgaa tcacagaagg atggcttgaa aaatcaactc cctcccagaa acttgctgca
     8881 ccaagcaaga tttgttgttc acctttttca aagcgtttct ttagctgatg aacatcccca
     8941 tttttatact gggccaagtg gctaactgta agtaaatccg atactgctag aagcatgtct
     9001 ttagcggtaa agagaaccaa aatcggttgc tggaaagctt gaatttccac tagtaaagca
     9061 gctacctctc tggcatagac ttctaaggag gtttctgtta ccagagggaa atctttgacc
     9121 ataaccactt cttgttcctg ttttccccga gattcaatct tgacaaattt ggcttcagga
     9181 tagcctaaaa ggtctgccaa agaaaccctc tgactaatct caagagtagc cgatactccc
     9241 aagacttggc aactctcagg aagtaaagag gacagaagag tacggcctga ttttgtagaa
     9301 gaaatctgaa ttttcttttg actcgtttca gttacttcaa gccagtaatc accttcagct
     9361 gtaaaatagc gaaccagctc atcaaagcct tccacttcta attctgaaaa atactgatgg
     9421 agattgtcca gagaatctaa gatatttttc ctagatttac cagactgaaa ttgttctatc
     9481 aagtagagac actcaaagcg aatactttct agtatccgtt gttgaaccct gttttcttct
     9541 cctactaaag ccttatcaat taaatcgata atagattgta tatcgtaggt ctcttgaagc
     9601 agattttcta gagctaacaa aatcttttgg acttcatcaa taatcagtaa acggtcactg
     9661 acaaattcag gattatcttc aagtctggtc acgagatagg catgattagt cactaaaagc
     9721 ttgcaagtct ctgccctttc ttgactacgt ttccaaaaat cttccgtcac aaataagctc
     9781 tgggatgata aattcccatc atgacgaagg tctgctagaa aatgttggta acggtagagt
     9841 tgcccgattt catccaaatc tcctgtctct gtctcagtaa gccagaccaa gacttgcatt
     9901 ttaaagcgtc taaataagcg attttcatca ttttcctgca aggaatgata aaaggcatcc
     9961 aacttcagat aattttgtgg tccctttaag ctatgaatat ctgtatggaa cacttccttg
    10021 agacgtttac cttcttcttc catgatttga ttttgaagaa tctttgtcgg aacactaaga
    10081 acaatttgtc gctctttgga ttgagataaa gcgggtaaga gatagccata ggttttccca
    10141 atccctgtcg gcgcttgaat cagagagaaa ggttcatctt tcaatagcaa gccaacctct
    10201 ttagcaaaac tttcttgttc ctccctcact tcaaggttca acagagaaat atttttagaa
    10261 aagtcttgag atagttttcg tagctccaga gaagctgccg ttttcttaaa atacagacct
    10321 tgaacttgga ccaagtctgg agaactcagg atagattggt tgcgataagt ttcctcaata
    10381 accaggtaag actcatatag gagagcgtca gccatttcca gcaagcgttc caagagacct
    10441 ttaggaagct gggtcatctt ttcccgtaaa aaaagaagta attctgctgt agcttgggca
    10501 tctgaaaggg ctgtgtgtgc gtgtttaaga ggaattccta attctcgaca caaaatcggc
    10561 aagctatatt tttccagttc agggaaaaag acctgggcca attcgaccgt atcaacacga
    10621 gggtttctta gctcatagcc ttcaaaaaat aaattttccg ccaagagatt agcatcaaac
    10681 tgaacattat gggctacaaa aatcccatcc tccaccaagt caaagatttt tctggcaact
    10741 tgcgaaaaat caggtgcttg cgccagacgt tggtctgtca atcctgtcag ttctttgata
    10801 tgagcatcca agggttcatg tggattgaca tccgtcgtat agtgatcgac gatttctcca
    10861 tcctcaatca cgacaattcc cacttggata attttagcct tactacctgt gctagttgcc
    10921 tctaaatcca ccacaacata gcgattacca atcgttttca ttataaaaaa ttataccaaa
    10981 aaaagggcca tttggcacct gcaaacatag gataattttc aaactcaaga acactacttt
    11041 tcttagaaat cccatcgaat agagcattct agcctgctga tttttttaaa atagtgaaga
    11101 aatacgaaaa attgagagaa gaaatgtttt catcttcctt ctctcaacga atcatgtatt
    11161 ttatttaacc atgtcaggat cgtagtcata aaatcctgta tcaaggaaac ggtttttagg
    11221 gtgaagttta cgaacttctt catccagcaa gaaggcttgg tcatggctaa agttgccctc
    11281 ttgaatcaag ctacgcgctt ggataaagag ttttgcaatc tcaacaaagt tctgaccagg
    11341 agtgtagagc ccttctagtt tccagcgagt aaagccatgc tccaccaatt ctgttaattt
    11401 gatcatcaaa tcaaggtcat tgttggcaaa gatatgggtc ccatgattat cttcaaaaat
    11461 ggaatagtgg ctctctggat cacttggctc agccaagaag aggtcacgtt tatgcgtctt
    11521 ttcatcatcg atatgtgtaa agttatagta gttttgcaag agtggacgtt tagaatgatg
    11581 gatgacgcta gcaccgtaaa ccaaaacttc agcaggaatt tccaaaatct ctggcatttt
    11641 gaaaagttca gctgatggaa tttcacgcgc caaaacagcc tcagatgcgc cagccttttg
    11701 tccccagaag ttaatctgac gactgctagt taccatggtt gaagcatcgt agatggtctt
    11761 aaatgaataa ccatcgcggt taactacgta aaagacgcct gcatccccaa tcgtaatata
    11821 gtctgtcttg atttcttcca agaagtctaa gaaaggcttg atacggtcca tcatatcttg
    11881 gtgcatgaga gcattgaccg caacgatcaa ttccttacca gcatcatgaa ccaacttagc
    11941 gatttcacgt aattggtcat aactaaaggt cgttggcaga cgaaggccaa aatctttctc
    12001 accgacatag atacggtcta cgccagcttc gagtagttgt tcaacttgtt caatactttc
    12061 agcagttgct gtaatgacaa tcttttccat aagaaaaatt ataccacatt tctccaaaat
    12121 cagccatgct ttgaaaatga aaagggactt tattcttttt gtaacctttc tgtaataatt
    12181 ctctgccgaa aaaatgataa aataggtatg tactgttaag gagagaatca tgcccgtaag
    12241 aaaattacaa tcctatgagg tagactatca agaagaatta aaccagcagc ttcctcatta
    12301 ccaagcttat acacctgaag cgcaatctga tgccaatctc aaggaaatcc tattttttat
    12361 taatatcgct gttttttgta tctgtattgc tatctttagt tttatctttt tagcattaaa
    12421 attatcaact gctcttgcct ttgccgcagc aatcggattc agcttacttg ttttaaaagt
    12481 tcaacggtct attatcaaac gaaaacgtag aagataaatc caaaatatcg ccccaattgg
    12541 agcgatattt ttattttttc tttttagatg gtgtctgaat ggcaatcttc acttcaaaga
    12601 ttgttccctt gggtttatta tctttgacag taacagttcc ttttagagca tctacaattt
    12661 gcttggctag ggataatcct aaaccaaaac cacctttttg ccgggttcta gctttgtcta
    12721 ctcgataaaa acggtcaaaa attttctttt tatcttctgt cgaaataccg attccattat
    12781 cagaaacaag taaataaaga ttgcgatcgg tcgccgagat aagaaaatca atttcaccat
    12841 cctcctcagt atacttgacg gcattatcga aaagaatggt catcagttgt ttcagaagaa
    12901 gctgatctgt gacaattgtt cgatggatac gattttcaaa acggaagaca cgattatttt
    12961 ccgaagcaat catctcatag tttgtgaaag ttgtattaaa aaagctagtt ggaacttctg
    13021 caagctccgg cttaatccca tcatctctcc gagctaagtt cagcaagctt gtcgttaaaa
    13081 aacgcatatt tcggacttct tccaaactcg atgcaatgct ttcgctcaca tccataatgg
    13141 tagcttctgg cttacgaaaa agggtctcta agcgattttg caaaactgcg agtggagttc
    13201 gtaactcatg actggcattt tccacaaaag actgttgctt ctgcatactc tcaagcaggg
    13261 gcctaacact gaccctagct agatagagac tggcaagtaa agacaaaatc cagaaactag
    13321 ccatcacgac cacaatcaat tgctcatgct tttgactagc ctgctccaac tgactggtat
    13381 taatcaagac agcagcatac ttgatattgg ttgaaaccga actaatattg gtctccatca
    13441 aaatcacacg atagatttct tcctgcccat agctattaaa aacctgaatc tggtagatat
    13501 gtcctagttc tttcttttct aacttaatct tatccaagcc caaaaatcga tttccagaaa
    13561 gaagttgagt aaagtcttta tcaaagagaa tgacttccgt attggaactg acattaggtt
    13621 ttatttctac tttactagcg tccgccctag cattttctaa atctttaatc tcttctgttg
    13681 ccctatttat agccagctga ataactgctt gaggattttc actcagtcca tgaagcttat
    13741 cgtccaccga agtataaaga ctcgaatgca tgacttgtaa aataatcaga gtcattgtag
    13801 aaaaaatcag ggtgaagaca ccgaagttgc ggataaaata actaaagtca tccgcatacc
    13861 atgttttttt aagtttactg aacatctttt aaaagatacc caacactacg caaggtttgc
    13921 aaattctctg caaaagtggt tccctttaat ttcttacgga cttttgaaac atagacttcg
    13981 acaaccgaaa tcgttgtatc actatcaaat ccccatagac ggtcaaaaat ctgcgtctta
    14041 ggcaaaatca cattttgatt ttgaaggaaa taaactagta aatcgaactc tttccccagc
    14101 aattcgacag gagtatcttc aactttaacg gtattggttg ataaattaac cacgatattc
    14161 ccataagtca aggtgttttc attaaacttc cctgaacgtt tgagaagggc ctgaattcgc
    14221 attttaagtt cttctaggta gaaaggtttg gtcagataat catccgctcc cagttcaaat
    14281 ccatgtccct tgtcatccaa actttccttg gcagtcataa tcagaactgg tgtcgtaatt
    14341 cccttttcac gcaattcttt taagacttgg aaaccatttt tttctggcaa catcaaatcc
    14401 agcaaaatca agtcatagac accactctca gcttcgtaga gaccttcttc tccatcaaat
    14461 acctgcataa catccgcaaa atcgtctaaa aagtcaaata ctgaatttga cagacctagg
    14521 tcatcctcaa ccaataagat ttttatcatg agaaactcct ccttattaaa actattatac
    14581 caaatttgcc ttaaaaaaaa ctcaactctc tgcattttac atgagatagc tgagttttc
//
LOCUS       DBERCW010000043        14018 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.043, whole genome shotgun sequence.
ACCESSION   DBERCW010000043 DBERCW010000000
VERSION     DBERCW010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14018
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.043"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(298..1989)
                     /gene="argS"
                     /locus_tag="ACL72M_001766"
     CDS             complement(298..1989)
                     /gene="argS"
                     /locus_tag="ACL72M_001766"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGS0716854.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2125..2571
                     /gene="argR"
                     /locus_tag="ACL72M_001767"
     CDS             2125..2571
                     /gene="argR"
                     /locus_tag="ACL72M_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0716855.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2622..5156
                     /gene="mutS"
                     /locus_tag="ACL72M_001768"
     CDS             2622..5156
                     /gene="mutS"
                     /locus_tag="ACL72M_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGS0716856.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5303..6997
                     /gene="patA"
                     /locus_tag="ACL72M_001769"
     CDS             5303..6997
                     /gene="patA"
                     /locus_tag="ACL72M_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGS0716857.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7147..7590)
                     /locus_tag="ACL72M_001770"
                     /pseudo
     CDS             complement(7147..7590)
                     /locus_tag="ACL72M_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7788..9554
                     /gene="patB"
                     /locus_tag="ACL72M_001771"
     CDS             7788..9554
                     /gene="patB"
                     /locus_tag="ACL72M_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGS0716858.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9693..10382
                     /locus_tag="ACL72M_001772"
     CDS             9693..10382
                     /locus_tag="ACL72M_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS0716859.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10386..10565
                     /locus_tag="ACL72M_001773"
     CDS             10386..10565
                     /locus_tag="ACL72M_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716860.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10552..11901
                     /locus_tag="ACL72M_001774"
     CDS             10552..11901
                     /locus_tag="ACL72M_001774"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGS0716861.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12025..13485
                     /gene="gltX"
                     /locus_tag="ACL72M_001775"
     CDS             12025..13485
                     /gene="gltX"
                     /locus_tag="ACL72M_001775"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGS0716862.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            13499..13930
                     /locus_tag="ACL72M_001776"
     CDS             13499..13930
                     /locus_tag="ACL72M_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS0716863.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
BASE COUNT         4103 a         2697 c         3161 g         4057 t
ORIGIN      
        1 tatttggtta ggtgaattag tgaagtgttt aggcaagtgt ctctggttac gacgtcatgg
       61 cctctaaatc gattatattt aggggtcatg actagtgaag cagttagcta gttcgcatat
      121 aagcggctag cgtctaacaa ttaggaactt tagttccaat aactttaaga ttacgacgtt
      181 ttaggacata aatcgatcat atttatgtcc taaaactagt gaagcgccta gccaaagtcc
      241 gaataggatt tggcgttagt tacttagatt gctttgcaat caagtaactt tggcgattta
      301 catcttctct ggcgcttcta ctccaagcaa gcgaagggct tctttgagaa cgactgcggt
      361 tgcgtagctg agggctagac ggctgtcgcg ttctgggctt tcatccaaga tacgtgtatg
      421 tgcatagtat ttgttaaagg attgagccag gctaattgca aatttagcaa tgatagaagg
      481 ttcaaagtta tctgccgcac ggttgataat acgtgggaag tcttgaatga gtttaatgat
      541 ttcccagctt tcagtatcat tcaagctata gttgccagct gtttctggtt tgaaatcggc
      601 tttgcgtaag atagattgga tacgagcgta ggcatattga acgtaaggtc cagtttcacc
      661 ctcgaaggat accatagctt ctaggtcgaa gtcgtatcca tttgtacggt cagttttgag
      721 gtcatagaat ttaatggctc caaccccaac agcatgtgct acttggtctt tgttttctag
      781 ttcaggattt ttagcctcga tttggacctt ggcacggcta acagcctctg caacagtagg
      841 ctctagcaag atgacattcc ctttacgagt agagagcttc ttcccttctt ttgtaaccag
      901 accaaaagga acgtgggtaa tgtcgtcact ccaatcgtag cccatctctt gcaagacagc
      961 tttgagttgt ttaaagtggg cagattgctc ttgaccaacg acgtagatag atttagcaaa
     1021 ttggtattca tttttacggt agagggctgc agccaagtca cgtgtgatat agagagttgc
     1081 accatcagac ttcttgatga gggctggatg ttcaattcca tatttctcaa gattcacaac
     1141 ttgggcacct tctgattcaa gaagtagtcc tttttcagaa agaatgtcta caactgcatc
     1201 catcttatca ttgtagaagg cttctccgtt atagctgtca aattcaacct tcaattcatt
     1261 gtaaaggcgg ttaaattcca ctaaactttc atcgcggaac cattgccaaa gagcgagagc
     1321 ttcctcatct ccattttcaa gtttacggaa ccattcgcgc gcttcttcat ccaagctagg
     1381 gtcattttca gcttcagcgt tgatgcggac atagagttta aggagttcat cgattggatg
     1441 agcttttaca gcttcttcgt cgccccattt tttgtaggca acaatcaaca tcccaaattg
     1501 tttaccccag tctcccaaat ggttgacctt gaccgtttga taaccgattt tttggaaaat
     1561 atgtgacaag ctatctccga taacagttga acgcaggtgg ccaatagaaa atggtttagc
     1621 gatattcgga ctagacatgt cgataacaac attttcttgt ttgccaatat tttggtcagc
     1681 atagtgttct ttttcagtgg taacagcttg caatacttga gcagaaatgg cagatttatc
     1741 aaggaaaaag ttaacgtaag gtcctgttgc gacaactttt tcaaaggctt ggctgttcat
     1801 tttttcagcc agttcagccg caatcatttg tggtgcttta cgttcgactt tggcaagaga
     1861 aaaagcaggg aaagcaatgt ctcccatttc tgagttttta ggggtttcca gtaactttaa
     1921 aatagcctct tggtccaggc tatcaatgat gctagataat tcgctagcaa tcaattcttt
     1981 tgtattcatt aagagctcct ttttggactt ttctactatt ttatcacaat tttaaagaaa
     2041 gaagaaaaaa tttttgaaat ctcctgtttt tttggtataa tatggttata aatatagtta
     2101 taaatatgca cgcaagagga ttttatgaga aaaagagatc gtcatcagtt aataaaaaaa
     2161 atgattactg aggagaaatt aagtacacaa aaagaaattc aagatcggtt ggaggcgcac
     2221 aatgtttgtg tgacgcagac aaccttgtct cgtgatttgc gcgaaatcgg cttgaccaag
     2281 gtcaagaaaa atgatatggt gtattatgta ctagtaaatg agacagaaaa gattgatttg
     2341 gtggaatttt tgtctcatca tttagaaggt gttgcaagag cagagtttac cttggtgctt
     2401 cataccaaat tgggagaagc ctctgttttg gcaaatattg tagatgtaaa caaggatgaa
     2461 tggattttag gaacagttgc tggtgccaat accttattgg ttatttgtcg agatcagcac
     2521 gttgccaaac tcatggaaga tcgtttgcta gatttgatga aagataagta aggtcttggg
     2581 agttgctctc aagacttatt tttgaaaagg agagacagaa aatggcgata gaaaagctat
     2641 cacccggcat gcaacagtat gtggatatta aaaagcaata tccagatgct tttttgctct
     2701 ttcggatggg tgatttttat gaattatttt atgaggatgc ggtcaatgct gcgcagattc
     2761 tggaaatttc cttaacgagt cgcaacaaga atgccgacaa tccgatccct atggcgggtg
     2821 ttccctatca ttctgcccaa cagtatatcg atgtcttgat tgagcagggt tataaggtgg
     2881 ctatcgcaga gcagatggaa gatcctaaac aagcagttgg ggttgttaaa cgagaggttg
     2941 ttcaggtcat tacgccaggg acagtggtcg atagcagtaa gccggacagt cagaataatt
     3001 ttttggtttc catagaccgc gaaggcaatc aatttggcct agcttatatg gatttggtga
     3061 cgggtgactt ttatgtgaca ggtcttttgg atttcacgct ggtttgtggg gaaatccgta
     3121 acctcaaggc tcgagaagtg gtgttgggtt atgacttgtc tgaggaagaa gaacaaatcc
     3181 tcagccgcca gatgaatctg gtactctctt atgaaaaaga aagctttgaa gaccttcatt
     3241 tattggattt gcgattggca acggtggagc aaacggcatc tagtaagctg ctccagtatg
     3301 ttcatcggac tcagatgagg gaattgaacc acctcaaacc tgttatccgc tacgaaatta
     3361 aggatttctt gcagatggat tatgcgacca aggctagtct ggatttggtt gagaatgctc
     3421 gctcaggtaa gaaacaaggc agtcttttct ggcttttgga tgaaaccaaa acggctatgg
     3481 ggatgcgtct cttgcgttct tggattcatc gccccttgat tgataaggaa cgaatcgtcc
     3541 aacgtcaaga agtagtgcag gtctttctcg accatttctt tgagcgtagt gacttgacag
     3601 acagtctcaa gggtgtttat gacattgagc gcttggctag tcgtgtttct tttggtaaaa
     3661 ccaatccaaa ggatctcttg cagttggcga ctaccttgtc tagtgtgcca cggattcgtg
     3721 cgattttaga agggatggag caacctactc tagcctatct catcgcacaa ctggatgcaa
     3781 tccctgagtt ggagagtttg attagcgcag cgattgctcc tgaagctcct catgtgatta
     3841 cagatggggg aattatccgg actggatttg atgagacttt agacaagtat cgttgcgttc
     3901 tcagagaagg gactagctgg attgctgaga ttgaggctaa ggagcgagaa aactctggta
     3961 tcagcacgct caagattgac tacaataaaa aggatggcta ctattttcat gtgaccaatt
     4021 cgcaactggg aaatgtgcca gcccactttt tccgcaaggc gacgctgaaa aactcagaac
     4081 gctttggaac cgaagaatta gcccgtatcg agggagatat gcttgaggcg cgtgagaagt
     4141 cagccaacct cgaatacgaa atatttatgc gcattcgtga agaggtcggc aagtacatcc
     4201 agcgtttaca agctctagcc caaggaattg cgacggttga tgtcttacag agtctggcgg
     4261 ttgtggctga aacccagcat ttgattcgac ctgagtttgg tgacgattca caaattgata
     4321 tccggaaagg gcgccatgct gtcgttgaaa aggttatggg ggctcagacc tatattccaa
     4381 atacgattca gatggcagaa gataccagta ttcaactggt tacagggcca aacatgagtg
     4441 ggaagtctac ctatatgcgt cagttagcca tgacggcggt tatggcccag ctgggttcct
     4501 atgttcctgc tgaaagcgcc catttaccga tttttgatgc gatttttacc cgtatcggag
     4561 cagcagatga cttggtttcg ggtcagtcaa cctttatggt ggagatgatg gaggccaata
     4621 atgccatttc gcatgcgacc aagaactctc tcattctctt tgatgaattg ggacgtggaa
     4681 ctgcaactta tgacgggatg gctcttgctc agtccatcat cgaatatatc catgagcaca
     4741 tcggagctaa gaccctcttt gcgacccact accatgagtt gactagtctg gagtctagtt
     4801 tacaacactt ggtcaatgtc cacgtggcaa ctttggagca ggatgggcag gtcaccttcc
     4861 ttcacaagat tgaaccggga ccagctgata aatcctacgg tatccatgtt gccaagattg
     4921 ctggcttgcc agcagacctt ttagcaaggg cggataagat tttgactcag ctagagaatc
     4981 aaggaacaga gagtcctcct cccatgagac aaactagtgc tgtcactgaa cagatttcac
     5041 tctttgatag ggcagaagag catcctatcc tagcagaatt agctaaactg gatgtgtata
     5101 atatgacacc tatgcaggtt atgaatgtct tagtagagtt aaaacagaaa ctataaaacc
     5161 aagactcact agttaatcta gctgtatcaa ggagacttct ttgacaattc tccacttttt
     5221 tgctagaata acatcacaca aacagaatga aaaggagctg acgcattgtc gctccctttt
     5281 gtctattttt taaggagaaa gtatgctgat tcagaaaata aaaacctaca agtggcaggc
     5341 cctggcttcg ctcctgatga caggcttgat ggttgctagt tcacttctgc aaccgcgtta
     5401 tctgcaggaa gtcttaggcg ccctccttgc tgggaaatat gaagctattt atagtatcgg
     5461 ggcttggttg attggtgtgg ccgtagtcgg tctagttgct ggtggactca atgttgtcct
     5521 cgcagcctat attgcccaag gagtttcatc cgaccttcgg gaggatgcct tccgtaaaat
     5581 tcaaaccttt tcttatgctg atattgaaca atttaatgcg ggaaatctag tcgttcgaat
     5641 gacaaatgat atcaaccaga ttcagaacgt tgtcatgatg accttccaga ttcttttcag
     5701 acttcccctc ttgttcatcg gttcgtttat cctagcggtt caaaccttac cttctctgtg
     5761 gtgggtgatt gttctcatgg tagtcttgat ttttggtttg actgctgtca tgatgggaat
     5821 gatggggcct cgttttgcca agtttcaaac ccttcttgag cgcatcaatg ccattgccaa
     5881 ggaaaattta cgtggcgttc gtgtggtcaa gtcctttgtc caagaaaaag agcaatttgc
     5941 taagtttaca gaggtctcag acgagcttct tggtcaaaac ctttacattg gttatgcctt
     6001 ttcagtagtg gaacccttta tgatgttggt tggttacggg gcggtcttcc tctctatttg
     6061 gctggtcgcg ggaatggttc agtcggatcc gtctgttgtt ggttccatcg cttcttttgt
     6121 taattaccta agccagatta tctttaccat tgttatggtt ggatttttgg gaaattctgt
     6181 cagccgtgcc atgatttcca tgcgtcgtat tcgagaaatt cttgacgcag agccagctat
     6241 gaccttcaag gatatcccag atgaagagtt ggttggaagc cttagctttg aaaatgtgac
     6301 ctttacctat ccaatggaca aggaaccgat gctgaaagat gtgagcttta ctattgaacc
     6361 tggtcaaatg gttggtgtag ttggagcgac tggtgcagga aagtcaacct tggctcaatt
     6421 gattccacgt ctctttgatc cacaggaagg ggctatcaaa atcggaggta aggatattcg
     6481 agaagtgagt gaaggaaccc tgcgtaaaac agtttccatc gttctccaac gtgccattct
     6541 ttttagtgga acgattgcag ataacttgag acaggggaag ggaaatgcta ctctatttga
     6601 aatggagcgc gcagccaata ttgcccaggc tagtgaattc attcatcgta tggagaaaac
     6661 ctttgaaagt ccagttgaag aacggggaac caatttctct ggtggacaaa aacaaaggat
     6721 gtcgattgcg cgtgggattg tcagcaatcc acgtattctg atttttgatg attcgacctc
     6781 agccttggat gccaaatcag agcgcttggt gcaagaagct ttgaataagg acttgaaggg
     6841 gacgacaacc attattattg ctcaaaaaat tagctcggtt gtccatgcag acaagatctt
     6901 ggttctaaat caaggacgat tgattggtca aggcacgcat gcagacttgg ttgccaacaa
     6961 tgccgtttac cgtgaaatct atgaaacaca gaaatgaaag acaaactata agaaaagtca
     7021 atagttttat ctaaactatt tcttatttca atttgatgat ttggcgatga ttttagagca
     7081 cggcaaaaag ctattgaaaa agtccatttt ttcaaaggta atcctgtgtt aatttcagaa
     7141 attacatcac tttttgttcg tcaaatggca gctctttttt aggatataaa acagggttcg
     7201 gataagtttt tttgcaaggt ggatgatggc tacattgtaa tgttttcctt gttctaactt
     7261 agtcttaaga taggccttaa aagcaggtga aaagcgaggg catgctttgg cagcttgtat
     7321 gagtacctac cgcagatgag gggaaccccg tttgaccatt ctttctgcta aatcaatctg
     7381 acctgactga taaatagaag aatccagtcc agcgaaagct tgtaattgag caggattatc
     7441 aaaggcatga atatttcgaa tctcggctaa aatgaccgcc cctaaacgac ccccaatccc
     7501 agtaaccgtc gtgatgaccg agttgaactc agccatcaag tcattgacac attttttcgc
     7561 cttgtcaatg agcctcttgt aatgtttgat gttttcatta caagagataa aacgtttatg
     7621 cgttatcaaa ctcattacca attgaaacaa aaagctgtgg ttagatcctt tcggaaattg
     7681 tcaagcgatt ggaggaaatg aactaatcca cagcggctta ttccaagtat accacttggg
     7741 ctttggcagt agctaactgc gctaaatata atataaggag gagtaaaatg aagacagttc
     7801 aatttttttg gcattatttt aaggtctaca agttctcatt tgtagttgtc atcctgatga
     7861 ttgttctggc gacttttgcc caagccctct ttccagtctt ttctggacaa gcggtgacgc
     7921 agctagccaa tttagttcaa gcttatcaaa atggcaatcc agaacttgta tggcaaagcc
     7981 tatcaggaat catggtcaat cttggcctgc tggttttggt tctatttatc tctagtgtaa
     8041 tatacatgtg tctcatgacg cgcgtgattg cagaatcgac caacgagatg cgcaaaggcc
     8101 tctttggtaa gcttgctcag ttgacggttt ctttctttga ccgtcgacaa gatggcgata
     8161 tcctgtctca ttttaccagt gatttggata atatcctcca agcctttaac gaaagcttga
     8221 ttcaggtcat gagcaatatt gttttataca ttggtctgat tcttgtcatg ttttcgagaa
     8281 atgtgacgct ggctctcatc accattgcca gcactccatt ggctttcctt atgctgattt
     8341 tcatcgtgaa aatggcacgt aaatacacca acctccagca gaaagaggta gggaagctca
     8401 acgcctatat ggatgagagc atctcaggcc aaaaagccgt gattgtgcaa ggaattcaag
     8461 aggatatgat ggcaggattt cttgaacaaa atgagcgcgt gcgcaaggca acctttaaag
     8521 gaagaatgtt ctcaggaatt cttttccctg tcatgaatgg gatgagcctg attaatacag
     8581 ccatcgtcat ctttgctggt tcggctgtac ttttgaatga taagtctatt gaaacaagta
     8641 cagccctagg tttgattgtt atgtttgcac aattttcaca gcagtactac cagcctatta
     8701 tccaagttgc agcgagttgg ggaagccttc agttggcctt tactggagct gaacgaattc
     8761 aggaaatgtt tgatgcagag gaggaaatcc gacctgaaaa ggctccaacc ttcactaagt
     8821 tgcaagaaag tgttgaaatc agtcatatcg atttttcata cttgcctgat aaacctattt
     8881 tgaaagatgt cagcatttct gcccctaaag gccagatgac agcagttgtt gggcctacag
     8941 gttcaggaaa aacgactatt atgaacctca tcaatcgctt ttatgatgtt gatgctggtg
     9001 gtatttattt tgatggtaaa gacattcgtg gctatgactt agatagtctt agaagcaagg
     9061 tgggaattgt attgcaagat tcggtcttgt ttagcggaac gattcgagac aatatccgat
     9121 ttggtgtgcc agatgctaat caggaaatgg ttgaggtagc agcaaaagca acccacattc
     9181 acgactatat cgaaagtttg cctgataagt acgatactct tattgatgat gaccagagca
     9241 tcttttcaac agggcagaag caattgattt caatcgctcg aaccctgatg acagatccag
     9301 aagttctcat tctcgatgaa gcaacttcaa acgtagatac ggtgacggaa agcaagattc
     9361 agcatgccat ggaggtggtt gtagcaggta gaactagttt cgtcattgcc caccgcttga
     9421 aaaccattct caatgcagat cagattattg tccttaaaga tggagaagtc attgaacgtg
     9481 gtaaccacca tgaacttttg aagctaggtg gcttttattc agaactctat cacaatcaat
     9541 ttgttttcga ataagaaaga agttgtccta tgtgggcagc tttttcttgt ccataaaaaa
     9601 tgtttatcac agccttaaaa aaaacatatt agacgaaagt cattttgagt gatatgatag
     9661 gactatcgtt agtattcgaa aggagaggca tcatggctag aacggttgta ggagttgctg
     9721 caaatctatg tcccgtagac gcagaaggca aaatcattca ttcatctgta tcttgtagat
     9781 tcgcagagat cattcgtcaa gtcggtggtc tccctttagt cattcctgtt ggtgatgagt
     9841 cagttgtacg tgattatgtg gaaatgattg acaaactcat tttgacagga ggccaaaatg
     9901 ttcatcctca gttttatgga gagaaaaaga ccgtcgaaag cgatgattac aatctggtcc
     9961 gtgacgaatt tgaattggca ctcttgaagg aagcgcttcg tcagaataaa ccaattatgg
    10021 caatctgtcg cggtgtccaa cttgtcaatg ttgcctttgg tggaaccctc aatcaagaaa
    10081 tcgaaggtca ctggcaagga ctacctttcg ggacatctca ctctattgaa acagtagaag
    10141 gaagcgtggt ggctaagcta tttgggaaag aaagtcaggt caactcagtc catcgtcaaa
    10201 gcattaaaga tttggcacct aatttccgtg taactgctat tgattcaaga gaccaaacta
    10261 ttgaagcgat tgagtctatc gacgagcacc gcattatcgg tttacagtgg catccagagt
    10321 ttctggttaa tgaagaagat ggcaatttag aattatttga gtatttattg aatgaactgt
    10381 aacgattgga acatctggtc gttctttctt ttattttttc aaaattttta gaatgtggca
    10441 ttttacgcaa acgtttgaat tctgataaaa attggagaaa ttcgacaaaa aaacttgaaa
    10501 aaaacgaagg taagcgttat gatagaaaag aagaaatatt ggaggaagaa catgtcacat
    10561 attaaatttg attattcaaa agttttagac aaatttgttg caccacatga agtggaatac
    10621 atgcaatcac aagtaacagc agcagatgaa ttgatccgta aaggaactgg tgctggtagc
    10681 gacttcttgg gatggttgga ccttcctgaa aaatacgacc gcgaagaatt tgaccgcatc
    10741 ttgaaagctg ctgagcaaat caagtcagac agcgatgttt tggttgtgat cggtattggt
    10801 ggatcttacc ttggtgcaaa agcagcaatc gacttcttga atcaccattt tgctaacttg
    10861 caaacaaaag aagaacgcaa agctccacaa atcctttacg caggaaactc aatctcatct
    10921 acttaccttg ctgacttggt agagtatgtt gcagacaaag acttctcagt aaacgtaatt
    10981 tctaaatcag gtacaacaac tgaaccagcg attgctttcc gtgtctttaa agaactcttg
    11041 gttaagaaat acggtcaaga agaagctaac aaacgtatct atgcaacaac tgaccgccaa
    11101 aagggtgctg ttaaggttga agcagacgct aacggttggg gaacatttgt tgttccagat
    11161 gatatcggtg gacgcttctc agtattgaca gccgttggtt tgcttccaat cgcagcatca
    11221 ggagctgaca tcaaagctct tatggaaggt gcgaatgcag ctcgcaaaga ctacacttca
    11281 gacaaaatct ctgaaaacga agcttaccaa tacgcagtcg ttcgtaacat cctttatcgt
    11341 aaaggctatg caactgagat cttggtaaac tatgagccat cacttcaata cttctcagaa
    11401 tggtggaaac aattggctgg tgaatcagaa ggaaaagacc aaaaaggtat ctacccaact
    11461 tcagccaact tctcaactga cttgcactca cttggtcaat ttatccaaga aggaactcgt
    11521 atcatgtttg aaacagttgt ccgtgttgac aaacctcgta aaaacgtgct tattcctact
    11581 ttggaagaag accttgacgg acttggttac cttcaaggaa aagacgttga ctttgtaaac
    11641 aaaaaagcaa ctgacggtgt tcttcttgcc cacacagatg gtgatgtacc aaacatgtat
    11701 gtgactcttc cagagcaaga cgctttcact cttggttaca ctatctactt cttcgaattg
    11761 gcaattgccc tttcaggtta cttgaatgct atcaacccat ttgaccaacc aggtgttgaa
    11821 gcttataaac gtaacatgtt tgcccttctt ggaaaaccag gatttgaaga attgagcaaa
    11881 gaacttaacg cacgtctata atagaagaaa agagtggttt gcccactctt tttactctct
    11941 ttatccatag aaattggact cagccaagac ttgtgatata atatagaaag caaaaaggca
    12001 gacgcctaga taataggaga aactatgtca aaagatatcc gcgtacgtta cgcaccaagt
    12061 ccaacaggac tactacacat cggaaatgcc cgtacagcat tgtttaacta cttgtatgcg
    12121 cgccatcatg gtggaacatt tctcatccgt atcgaagata ctgaccgtaa acgccatgtc
    12181 gaggatggtg aacgttcaca acttgaaaac cttcgctggt taggcatgga ttgggatgaa
    12241 agtccagaat cacatgagaa ttatcgccag tctgagcgtt tggacttgta tcaaaaatac
    12301 attgaccaac tattagctga aggaaaagcc tataaatctt acgttacaga agaagagttg
    12361 gcagctgaac gtgaacgtca agaagtagct ggcgaaacac cacgctacat caatgaatac
    12421 cttggtatga gtgaagaaga aaaagcggct tatatcgcag aacgtgaagc agctggtatc
    12481 ataccaacag ttcgtttggc tgtcaatgag tcaggtatct acaagtggca tgatatggtc
    12541 aaaggtgata tcgaatttga aggtggcaat atcggcggtg actgggttat ccaaaagaaa
    12601 gacggttacc caacttacaa ctttgccgtt gttatcgatg accacgatat gcaaatctct
    12661 catgttatcc gtggagatga ccatattgct aatacaccaa aacagcttat ggtctatgaa
    12721 gctcttggtt gggaagctcc agagtttggt cacatgacct tgattatcaa ctctgagact
    12781 ggtaagaagt tatctaaacg tgatactaat acacttcaat ttatcgaaga ttaccgaaag
    12841 aaaggttacc ttccagaagc agtctttaac tttattgctc ttcttggttg gaacccaggt
    12901 ggtgaagatg agattttctc tcgtgaagaa ctcattaaac tttttgatga aaaccgcctc
    12961 agcaagtcac cagcagcctt tgatcagaaa aaattagact ggatgagcaa tgattatatc
    13021 aagaatgcag accttgaaac catctttgaa atggcaaaac cattcttaga ggaagcaggc
    13081 cgtttgactg acaaggctga aaaattagtt gagctctata aaccacaaat gaaatcagta
    13141 gatgagatta tcccattgac agatcttttc ttctcagatt tcccagaatt gacagaagca
    13201 gagcgcgaag tcatgacggg tgaaacagtt ccaacagttc ttgaagcatt caaagcaaaa
    13261 cttgaagcga tgacagatga tgaatttgtg acagaaaata tcttcccaca aattaaagca
    13321 gtccaaaaag aaacaggtat taaagggaaa aatcttttca tgcctattcg tatcgcagtt
    13381 tcaggcgaaa tgcatgggcc agaattacca gatacaattt tcttgcttgg acgtgaaaaa
    13441 tcaattcagc atatcgaaaa cattctaaaa gaaatctcta aataaagagg atacaataat
    13501 ggacatctgg gaaaagatgt acgaagaagc acagaaacta tacaatccac atgaagtatc
    13561 agactttgtt tatgccaatc atgttgtagc tgcagtagaa gcaggagatg gacaaatatt
    13621 tacaggattc tgtatggagg gaacctgtgg tgttttccat ctctgcgcag aacgggcgac
    13681 cctcttcaat atgtaccaat tttcaggaca aactaaggtt aagaaagtat tagcctttcg
    13741 agacaaacca ccttatggtg gaagttcagc catgccttgc ggtgcttgta gagaattcct
    13801 tttagagctt aatgctgaaa ataaagatgc agaattcatg atggactata atataagaaa
    13861 aacagttaaa gtcgcagaac taatccctta ttggtgggga gaagaacgtg cttctaagtt
    13921 taatgagtga tagaagagtc agtataattc tggctctttt tactataagt tgaaaaaata
    13981 aaaaaaatta gaaaaagtag ttgacaaaat ttgaaaag
//
LOCUS       DBERCW010000044        14013 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.044, whole genome shotgun sequence.
ACCESSION   DBERCW010000044 DBERCW010000000
VERSION     DBERCW010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.044"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            72..1331
                     /locus_tag="ACL72M_001777"
     CDS             72..1331
                     /locus_tag="ACL72M_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGS0716864.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1407..1542
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1581..2081
                     /gene="rplJ"
                     /locus_tag="ACL72M_001778"
     CDS             1581..2081
                     /gene="rplJ"
                     /locus_tag="ACL72M_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGS0716865.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2157..2525
                     /gene="rplL"
                     /locus_tag="ACL72M_001779"
     CDS             2157..2525
                     /gene="rplL"
                     /locus_tag="ACL72M_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGS0716866.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2712..2882
                     /locus_tag="ACL72M_001780"
     CDS             2712..2882
                     /locus_tag="ACL72M_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716867.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2882..3130
                     /locus_tag="ACL72M_001781"
                     /pseudo
     CDS             2882..3130
                     /locus_tag="ACL72M_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3144..3484
                     /locus_tag="ACL72M_001782"
                     /pseudo
     CDS             3144..3484
                     /locus_tag="ACL72M_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3477..3857
                     /locus_tag="ACL72M_001783"
     CDS             3477..3857
                     /locus_tag="ACL72M_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS0716868.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3870..4103
                     /locus_tag="ACL72M_001784"
                     /pseudo
     CDS             3870..4103
                     /locus_tag="ACL72M_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            4106..4693
                     /locus_tag="ACL72M_001785"
     CDS             4106..4693
                     /locus_tag="ACL72M_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0716869.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4895..5032
                     /locus_tag="ACL72M_001786"
     CDS             4895..5032
                     /locus_tag="ACL72M_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGS0716870.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5211..7820
                     /locus_tag="ACL72M_001787"
     CDS             5211..7820
                     /locus_tag="ACL72M_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGS0716871.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKSMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7853..9793
                     /locus_tag="ACL72M_001788"
     CDS             7853..9793
                     /locus_tag="ACL72M_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HGS0716872.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGISSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRAPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAADHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9790..11397
                     /locus_tag="ACL72M_001789"
     CDS             9790..11397
                     /locus_tag="ACL72M_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0716873.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11412..12152
                     /locus_tag="ACL72M_001790"
     CDS             11412..12152
                     /locus_tag="ACL72M_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716874.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12155..13474
                     /locus_tag="ACL72M_001791"
     CDS             12155..13474
                     /locus_tag="ACL72M_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716875.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            13608..13745
                     /locus_tag="ACL72M_001792"
     CDS             13608..13745
                     /locus_tag="ACL72M_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGS0716876.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         4686 a         1951 c         2765 g         4611 t
ORIGIN      
        1 acacctacgg caaagtgaat ctgaagtggt ttgaagagag tacaacttgt cttttaaaaa
       61 aggagtctat aatgaaagtc tttcagcatg taaatatcgt gacttgtgat caaaatttcc
      121 atgtttatct tgatggaatc ttagcagtca aggattctca aatcgtctat gtcggtcaag
      181 ataagccagc gtttttagaa caagctgagc agattataga ctatcaggga gcttggatta
      241 tgcctggttt ggtcaattgt cacacccatt ctgcaatgac aggtctgaga gggatccgag
      301 atgacagcaa tctccatgaa tggctcaatg actatatctg gccagcagaa tctgagttta
      361 ctcccgacat gactaccaat gcggtcaaag aagccctgac agagatgctc cagtcaggaa
      421 caacaacctt taacgatatg tataatccca atggtgtgga tatccagcaa atttatcagg
      481 tggtgaaaac ttccaagatg cgttgttatt tttctccgac tctcttttct tcagagacag
      541 aaacaactgc tgagactata agcagaactc gatccatcat agacgaaatc ttaaaatata
      601 aaaatccaaa tttcaaggtt atggtagcac ctcattctcc gtatagctgc agtagagact
      661 tgctggaagc gagtttggaa atggcaaaag agctaaatat tccgctccat gtccatgtgg
      721 cggagaccaa ggaggagtca ggaattatcc tcaaacgata cggcaaacgc ccccttgctt
      781 ttcttgaaga actgggttat ttagatcatc cgtccgtatt tgctcacggg gtcgaattaa
      841 acgagagaga aattgaacgc ttggcatctt ctcaagtggc tatcgcccac aatcctatca
      901 gtaacctcaa actggcatca ggaattgctc caattatcca gctccaaaaa gcgggagtag
      961 cagtcggaat tgcgactgac tcggttgctt ccaataacaa tctagatatg tttgaggaag
     1021 gaaggactgc agctcttctt cagaagatga aaagtgggga tgccagccag tttccaatcg
     1081 aaacagctct caaggtactg acaatcgaag gggctaaggt ccttggaatg gaaaatcaga
     1141 taggaagtct ggaagtcggc aagcaagcag attttctggt cattcaacca caagggaaaa
     1201 ttcatctcca acctcaggaa aatatgctgt ctcacctggt ttatgcagtt aaatctagtg
     1261 atgtagatga tgtttatatc gccggagaac aggttgttaa gcaaggtcaa gtcctgacag
     1321 tagaacttta aaagaaaaat cacgaaaaat tttaaaaaaa gtttgcaaaa atcttgcatt
     1381 ctttttttga ctatgctata cttatatacg gtttaaaaaa actgcctaag acagtagggg
     1441 agatcgactc ataaatatcc taccgaggac aaaacgtatc atgtaaaaag aagcgtattg
     1501 tactttcgtg tctaggtttg ggcgcgtttt tctttttgaa aaattcccca agcaaaataa
     1561 ttacggaggt gaacacacta atgagtgaag caattattgc taaaaaagcg gaactagttg
     1621 acgtagtagc tgaaaaaatg aaagctgctg catctatcgt cgttgtagac gctcgtggtt
     1681 tgacagttga gcaagataca gttcttcgtc gtgagcttcg tggaagcgaa gttgagtata
     1741 aagttattaa aaactcaatc ttgcgtcgtg cagctgaaaa agctggtctt gaagatcttg
     1801 catctgtatt tgttggacca tctgcagtag cattttctaa tgaagatgtt atcgcaccag
     1861 cgaaaatctt gaacgacttt tctaaaaacg ctgaagcact tgaaattaaa ggtggtgcaa
     1921 tcgaaggcgc tgtcgcatct aaagaagaga ttcttgcact tgcaactctt ccaaaccgcg
     1981 aaggacttct ttctatgctc ctttctgtac ttcaagcgcc agtgcgcaac gttgctcttg
     2041 cagtcaaagc ggttgcagaa agcaaagaag acgcggctta atcttaagct acatagcgta
     2101 gcctagctac gaaaaaaact attataaaat ttaaaactta tttggaggaa ataacaatgg
     2161 cattgaacat tgaaaacatt attgctgaaa ttaaagaagc ttcaatcctt gaattgaacg
     2221 accttgtaaa agctatcgaa gaagaatttg gtgtaactgc agctgctcct gtagctgttg
     2281 ctgcagctga tgcagctgat gctggtgctg ctaaagattc attcgacgtt gaattgacat
     2341 ctgcaggcga caaaaaagtt ggcgttatca aagttgtacg tgaaatcact ggtcttggtc
     2401 ttaaagaagc taaagaactt gttgacggtg caccagcact tgttaaagaa ggcgttgcaa
     2461 ctgcagaagc tgaagaaatc aaagctaaat tggaagaagc tggagcttca gttactctta
     2521 aataatagag tatcgcaatt tgattgcgga atccctattt accagtcttt gagagcgata
     2581 agcgattgat agaaactgat aaattgattt ggtttcctgc caaaaattct ttggcaggat
     2641 ttttgtttta ataaactttc gggggtagac actagattgt ctaccccttt ttttgtgttt
     2701 cggaggtaat tatgcaaaag gaaggacagt catcacgtca attcgtgaag agtcatctca
     2761 tgactatcat gggagttgat attgtaaaag caactcagtt agttgatgaa atggaacaag
     2821 taggtttaat ccgatttgat gaatttggaa atgttggaat tttagtcttg gagggacaat
     2881 aatgaagcgt attaccgcta atcaatatca gacatcagag cgttattata agctccccaa
     2941 acttttattt gagagtgaac ggtataagaa tatgaaactg gaggttaagg tggtttactc
     3001 agttttaaaa gatcggttgg agttgtcttt gagcaaaggt tggattgatg aggatggggc
     3061 tatttatttg atttattcca attcaaattt gatggcactt ttaggctgtt caaagtcaaa
     3121 attactctcc atgtgagttt gaagtgacat ttttagatga ttaccataaa aaacataact
     3181 acccactatt ttacgaatcc tatcttcaaa acgttatgga attccttgaa agtcaagaca
     3241 taaagaatgg ggttgatgcc tttgtagatg atcatcaaaa tctcgttttt gttttatatg
     3301 gacaaggcta tcgagccgag ggaaaagagg gaatacttac aacccaagta actgtaaaag
     3361 cttatgatga agacaagaaa ccgattaact tcgcaaattt attagattcc ttaatttatt
     3421 agattcctta atcgtgtcag aatatcaaat ggaaccgaat ctttgggagg tctcccatga
     3481 ttgatctcta tctaagtaaa aatagacaaa gaaatcaact tcttttagat ttcttccaaa
     3541 actatggcat agaggtatct tgtcattcag tttctgaaat gacaaaggac aaattaattg
     3601 agatgatgag ctattcttca gattgttttg agtttttatc tcccaattta ttacgattta
     3661 agaaccgtga caatctaaga ttaacggatt tcgttgagat aattttaaaa aatcctgaac
     3721 taaccatcag acttcctctt gcggtttcaa ataagcgagt ttatccaagt ctgaatttgg
     3781 aagaggctag agctctattg ccaagagata cgaaacaatt gatttacatg gcgcaaacac
     3841 attatttatc taactaaagg agaagcaata tggctgaacg attttgggag aacttgtcca
     3901 ttattttggc tgaaagaaat atcagctgga ttgagttaac cagaaaaatg tttgcgggag
     3961 agtttcacta tccaagtgaa ttgaatcgtt tgtatcaaaa gattcgccac tagaagatgg
     4021 aacaatgaat gcctcaaagt ccatgggtag aaaggattgt gcaggtatta gatttagatt
     4081 atgaagattt atttcggagg taactatgaa aagaataatt ccagtttata tattccaaca
     4141 agtaaatgtc ctattggtat ctctatactt attgaaattt ctttgtatcg gtgagttaac
     4201 tatactacag attctctatg gttcgtcact catttctttt ttatggatgt atggccaacg
     4261 caaacaagcg cataaggtca atatgaaatc taggatgaaa tggcttggtg ttgaatttgt
     4321 tagcctactg attataagtc tatgttttag tctgattcat gctcaaggaa gcacgaatca
     4381 agcaaactta attggccttc aacatcaaat tccttggttt tcatttttat tgttcttaat
     4441 caatgcgagt atggttgaag aatttctgta tcgagaaatt ttatggaatt tggtcagaaa
     4501 attagatatc agagttgctt tgacaagtgt tttatttgcc ttagcacatc atacaggaac
     4561 cattctagct tggtgtttgt atgtttcact tgggatgttt ttaggtatgg tgcgctataa
     4621 atctgactta tggggcagta tgggactaca tttggtgtgg aacctactag tttatagttt
     4681 gctgcttttt taaaataggt gacctgattt ttaggtaact tctaaaacta acttccagtt
     4741 ttgggagaga gatggaagtt actttgaaaa gttacggaaa cattattttc tatgtgacaa
     4801 cattgtataa ttgcttgcat tttactggtg gagagagtat aatgagggtg gataaagtac
     4861 ttaatcccaa aaatttaaat aggaggagct agctatggca gaagaagtat taaatcttca
     4921 attagtatct gttcaagttg acgaaacaga tgaagttgat ggaatgcgat ttagtacatt
     4981 cagtacaaat cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta
     5041 aattgtaaac tttagagatt ctctggagtt atggatgtcg ttccaatatg tgcacgttgg
     5101 aatgttagtg cttatatggg gagaatccaa aggattctcc ctttttattt aaataagtct
     5161 gtctagctat agatatatta agtttgataa aatttcttgg agattttgtt atggattata
     5221 atttcaattt ggagcatcct ttctttttca ctaataatga ttatagtaca gatactagca
     5281 taaagtacca agtaagtctg ccttttaatt ggcacgaagt aatgaataat gatgagtggg
     5341 tttatcaata ccctattgga aaatttgttg aaagacaagg gtggaaaata cacattagtt
     5401 cagagtataa cagttcacat gaattgttac aagatgtagc aaaaatttgc catgaaatgc
     5461 gaattccatt taaacatctt agtacagaag acaaatttat catgcgaaac gggaaattgg
     5521 ttagtcgagg attttctggt aaatttatta catgttatcc aaatcaaaat gaattagagt
     5581 cggttttgca aaggttagaa agtgccttaa agcaatataa tgggccatat attttaagcg
     5641 ataaacgttg ggatgaagca ccaatatatc tgaggtatgg tgtgtttagg ccgtcaaggg
     5701 atgatgaaaa gaaggttgct attgatgaat taattgttgg cgatgaagtt gttaaagatg
     5761 aacgtttacc agtatttaaa attccaaaag gtatagtgcc ccctgacttt ttgaataaat
     5821 ggcttgacaa gaaagataaa aaacagggag actttccctt tattatagat aatgcaatta
     5881 gattttcaaa cagtggtggg atatataatg ctaggctaaa agaagatggg aaaaaaataa
     5941 ttttaaaaga ggctagaccg tatacaggtc taggatttga tggtacttat tcttcagaga
     6001 aattagcttc ggagtgcaaa gcactaaaaa ttctaaatga atggagtgag acgcctaaaa
     6061 tatactggca cggtaagatc tgggagcaca ccttcttagg aattgaacat atgaagggcg
     6121 ttccactaaa tagatgggtt accaataatt ttcctttata tgaagttgtt gataagacca
     6181 aagattatct attgagagtt tcaaagatag tagaaaaact catcgattta acgaataagt
     6241 ttcattctga aaatgtatat catcaagatt tacatttagg aaatatcttg gttaaggatg
     6301 aagatgagat tagtataata gactgggaac aggctgtctt ttcaaatgat gaaaaagttg
     6361 tacataaagt tgcagcccct ggttttagag catggcgaga aacacttccc agtgagatag
     6421 attggtatgg tattagacaa atagctcatt atttatacat gccactagta actacatcgg
     6481 atttgacata caactatgta agtcaaacca ggatagaagg aaaaaaacta tttgagtctt
     6541 tgggttatac aagagaacat atagattatg tagaaagttt attgtcatat ctagattcta
     6601 aatgtccaca gattgagaat atttccagga aaaaagtttt aaaatccatg catgagatta
     6661 gaactatcga gagtgagcaa gatatacaag attttattat aaaattattg agagggttta
     6721 cgctaactta tggacagtgg cgtaaagaat ttcaatcaag attcttccca gttcattatt
     6781 atggtctgaa ttttaatcaa ggaattgcgt tttcagattt agctatcctt tggagttatc
     6841 aacaactagc taagaaagta aaaaatttca agtttgatga ctattatgag attcgaacac
     6901 aggttattaa tgaggcagta aataatttta agaaatcgtc cctttctggt ctttttgatg
     6961 gtaaaattgg tacaatctgg ctcatttatg aatttgggga gatagatcgg gcagttgaac
     7021 tttttacaac tcattttata gagatatttg agaattcaca aaataaaaat ttatatagtg
     7081 gacaggctgg aattttactg gttggactgt attttcttag taaaggggaa attgataata
     7141 aactaggaga agaaatacta attaggctta gagaatatac tttaaattat atagaaaatc
     7201 cagaaacttt ttgtaaagtt ggcgctagtg atgttcagag taatgatcct tatgagaatt
     7261 ttggtggatt actatatggt cacgcagggg tagcttggct cttcggtgaa gcttataaat
     7321 taactggtga aagtatctat aaaaatggtc tagaattggc tgtagataaa gaattagttg
     7381 cttataaagt agatagtaat aattcattgc agtacagcca aggtcataga ttactaccat
     7441 atctagcaac tggaagtgct ggcctgcttt tacttattaa tagaaataaa gaaatcttgt
     7501 caagcaaata cttaaaatat ttaacttctt tagagagggc aactgatgta gttttttgtg
     7561 tattaccagg tttatttaac ggattttgtg gtcttgaagt tgctaataat atatatagtg
     7621 atatcgatga taacttttca ggacaaaaga aattaattga acaactttat agatatttgt
     7681 gtgtaattga agaaggattt gttattgcgg gagataatgg tttaaagata acaacagata
     7741 ttgcttcggg atttgcgggt gttgcaattg gattggtatc aataatggat aataaattga
     7801 cgattcttcc tcaaatataa tatttagata ccattattaa ggggtcatac ttgtgaatca
     7861 gagtaatgaa atatttttaa atacaataca ggaaaaaaca cactataaga ggtctatctc
     7921 ttcatcattt caggaattaa aaaaatggaa ttctttgata tttaggagag ggcgatattg
     7981 gtaccaattt gataattgga gtatacccaa tactggtgta ataaaggaat ggtatgtcga
     8041 agataatgac tggattccta aggttagttc ttccagttta gacaattcaa attcacttaa
     8101 aattgtcttt gatgtggaaa aatatacttt gccagatgat agtatcttac aggatgttag
     8161 gatttcatct gatgagagtt atatagtttt ggttgtatcc tcactgcgta gcactaattt
     8221 aattggaata aaaaaatata ctatggaaga gttatttatc attgaagata tttcagtaga
     8281 aagttcgttc tatttgggta aattcggtgt tatgtatact cgctccaaag agtacgggag
     8341 gccaagtaag ttattctata aatcttttga tagctttaca gaagaggaac tgtttgaaga
     8401 aaacgaatgc tcttttcgat taaaaatagt ccacattgat agcaataatt gttttgtaaa
     8461 gtcagtagac tttcagaaag gcaggatttt tctatacagt ttcgaccgga cgggttttgt
     8521 tagacactct tacacagaaa cggtagcccc aacacctaga gatatcgctc tatttagtac
     8581 agaaaaagca cagtactttc ttgggatctc ttcaactgaa gaaaagaaag atcaactaat
     8641 tctaagggaa acttcttcgg gagacagagt ttctattact ataccatatc aagatagggc
     8701 tagaagagtt cactgtatag gacgttatat ccttttagac tgttcaaacg cagcgaattc
     8761 cgtcttttat cttgctacat ttaaaaataa tagtttgagg gagttgagtg ttaataagat
     8821 aacatttgat gaaaagacaa cactttatga aaattcattt tctgatcgtg ttcttctgtt
     8881 tttagagagg agaacttttt acgaaaaaat acttagtttt gatttaatag aaaatacatt
     8941 aaaaactgaa tttgaaagac ccatcataaa atcgaataat actaaatatt tttctaaggt
     9001 gatttggact aaaaaagaca gttatgatgt aagcataccg atttctttat tttggaaaag
     9061 tgaagatacg gatgagctcc caagaagaaa aaaatgtatt ctaagtgtct atggggctta
     9121 tggtaagaat gataattctg atttagatga aattatgtta tctataatag atgcaggttt
     9181 tatttatgct atagttcatg taagaggtgg aggctatttg ggtggtgaat ggtatcgctc
     9241 aggaaaggcg ttaaacaaat ggaattctat cagagatttt attgagggag taaattattt
     9301 aagggaaaat gatgtaattg acagtaagcg attaggttta ataacttcta gtgcaggtgg
     9361 aataattgct ggtgcggtgt tgaacgagga aaaaaattta ttgcaaagca ttctcttatt
     9421 ttcgccattt ataaatcctt atgatacact tcagaatcca aatgatcctc tttctaagac
     9481 cgaaatagca gagtggggag atattagagc ccctgaagta aaggcttata taaagtcata
     9541 ttcgcctatg caaaatattg aaaaggcacg agactcaaat actgttatag ttaatatttt
     9601 gggtgagaaa gacccatata ttaataataa cgaagtgata gagtggtcaa agaaattaaa
     9661 ttctattgga gttaaaagtt tgttgtattt aaacaaagca gctgatcatg gaggttttac
     9721 tccatcagat gttctcttaa tgattgatac tttaaattat ttctttgaag aagtgggaag
     9781 gaataactta tgaattattt aaaatttata aaaaagacta aacttatatt aatggggatt
     9841 ttaatatttc tatcttcgtt taatggtgtc ttgctctcag gaattattgt atatgcaggt
     9901 agtttaaatc agacttcctc attttctgac gttctaagat ttggtgctat aagtattctg
     9961 ggttggtcag caatctatat atcaaattac tatttagaag taacggaagc atcaataacg
    10021 aaagatataa atgtaaaaat taaacaagga tattttagag aacagtatct ttcttctgaa
    10081 atggttaaag attactcatc tattatttca gttttgtcaa atgatttgag attaatcgaa
    10141 gaaaactatt ttagacaaat ttttgaaata atttcttcaa tattgttgtt catcgtctct
    10201 ctaagtttta tgctttattt aaacttccta gtttcaataa tatttattgt attatcagca
    10261 ttgccgatta tagtacctgt ctttatgaag aagatgttgt ctaattcagc taatgagtac
    10321 tctaacagca atgcagagta tactcacata ataaaagaaa tttttaatgg ttttaagaca
    10381 ttaaaatctt attctgttac taaagaaata attagtttgt cggataaaaa gttggataaa
    10441 ctagaagatt ctacttttaa tttgaaacga tcagaggttc tttcaaaatt ggttgcagta
    10501 ctaatttcag gtttttgctt tctagttccc ttggttgtag gatgttattt tgtaatttat
    10561 cataaaagcc tttcttttag tgaactgata ggtattttct tagcaaacga taaagtttta
    10621 gggccgatac aatcaattgc ctattcatta aataagataa atacaaccaa agatttaagg
    10681 aaaccgtttt taaaatactt aagtggagag aagaatttta tagacgctga acatgataat
    10741 aacggactgt atacttcatc aatagatgag atacacatga aagatgttgt atattctatt
    10801 acaccagaaa ataaattaag tattgacttc tcatttaagt caccatttag ggtattatta
    10861 acaggaactt ctggtagtgg gaaaacaacg attttaaatt taattaatgg ttctttaaag
    10921 ccacaaaaag gttatgtaaa tttgttatca catgggaaaa agagttcaga ttcaatacca
    10981 acagttgatc agacaccata tatttttgac actactattc gtgagaacgt aactttattt
    11041 caaaatgaat atttttcaga tgatcagata attgaggtgt taaaaaaggt aaatctatat
    11101 gaagaattag aaaagataga tatactaaat tatcaatgtg gtgaaaatgg tagtaatttg
    11161 tctggaggtc aaaaacaaaa aatagcttta gctagagctc tgattagaaa taataaagtg
    11221 tacttatttg acgaaatatc agctaattta gataatgata attcaaattc catacatgat
    11281 attctgttca atttaggtat ttcatttatt gaagtttcac atcattatga cttaaatgac
    11341 aagagataca ctgatatata taaattggaa aatggaacac ttttcaaaat taagtgattg
    11401 gaggcaagaa tatggataaa gattatatat taaaagtgaa agggctgtat catcaatttt
    11461 tactaggaaa taataaaacg ttgcaagtgc tgaaaaatgt ttctctttct gcttcgagag
    11521 gagaatttat aagtattcta ggaattagtg gttctggaaa gtcaacttta ttaaaatgta
    11581 tttctagttt gcttgaacca acaagtgggg aagtaatttt aaatggaatc aacccctata
    11641 aaatcagaaa tgcaaaattg tcaagtataa gacgtaacga agtatctttt atatttcaag
    11701 catacaattt aataccttcc ctgccggtaa tagaaaatat agcacttcct ttgcgattat
    11761 cacaaaaaaa attaactatt aaaaatgtag aaaacttact caaaagaatg aagtttaatg
    11821 ctggcttaaa cgattttgtt ggaactctgt ctggtggaga acaacagaag gttgctatag
    11881 ctagagcggt tattgctgat agtgatataa tatttgctga tgagccaact ggggctttag
    11941 acagcgtttc tcgtgaagta atttttgaat tattgagaga gttagtaggg gcgggtaagt
    12001 gtgtaattat ggtaacgcac gatatagaat tggcctcgaa aactgatcgt gcattaatat
    12061 tgaaagatgg aaaaattttc aaagaacttc atagacctag cggggaagag ttgtataaaa
    12121 tcttagaggt acaatcaact acggaggaat agagatgctc agattagttt actatcaatt
    12181 tttacataat aagaaacaat ggttaggcgt ttcaccagta atttttgttt cgagtttagt
    12241 tatgggattg gctgttaatg gggtaattaa tgttgagaat aattcgcaag tatttgtcgg
    12301 acttccagat cctaaaccaa tttttatgtt tccgatagta ttcggaggag taacattatt
    12361 ctttgtgctc tctaacataa taaatatgtt ggttgaaatt tttagagatg attacgaact
    12421 tctggaggtg ttgggagcaa gtctccttca actatcattt cttgtggggg gacagatttt
    12481 tatcatttcc tcgattatta gttttattgc atatctatgc tctatatttg ttacgtcaaa
    12541 ttattattat tttttacaat actttttcgg ggaaaatata ttacctgata tccaatttca
    12601 aacgagtgct gttggatgta tcattacagt agtgttgatt tcatttttag cctttctaag
    12661 tggttgcttt tatacgttca agaagattag aaataggaag agttctaaaa taaggcatgt
    12721 tctttcaata gtaaaaagaa tactgctatt ggctggtttt agtgttatct ggttgctttc
    12781 tttgcaacaa attttccaag atagcacaat tttagcgaag gcccagataa tattcaatat
    12841 tgtaatctta gatattgtga ttatttatca attatctcct tttatacagt catgttttat
    12901 caaactactt tctataatta tatttagaaa taattttatg ttcattgttt cgaagtggaa
    12961 tttactatat cgtaagcctt atataaaatc tatcagtgct gcaattacag gagctatatt
    13021 actaatttct agttttcaaa tgatttctca gaatatacta tctcaatttc aagatgacag
    13081 tgatttagag ctaaaagtgg catttattgt ctatgtagga gcaccaattt tgatagtact
    13141 tgcaaatatt atttcaattg catttttgtc atcgcatcaa gaaaggattg agattcagca
    13201 atttgaaatt ttaggaactt ctaattacca gatggttaag attaaagttg gtgaggctat
    13261 atttttgaca tttgttactt cattaattgc atttttactt aacattaaaa ttatggcttt
    13321 aatatactac tctttagagg atattttaat agatgatatg aatcttttgg ggttaatact
    13381 tccaaatttt atagtgtcta ttattttatt tattttaata tttattacta aaagttccta
    13441 ttttatcttt aagaatgcaa aaattatttc ttaaaaattt gtaagttttc gctatataaa
    13501 atagttaaat ctattttgta tcattgcttg cattttactg gtggagagaa tataatgagg
    13561 gtggataaag tacttaatcc caaaaattta aataggagga gctagctatg gcagaagaag
    13621 tattaaatct tcaattagta tctgttcaag ttgacgaaac agatgaagtt gatggaatgc
    13681 gatttagtac attcagtaca aaccgttgcg gtaactggag tgcttttagt tgggaaaatt
    13741 gttaattcat ttaaattgta aactttaggg attctctgaa gttatggatg tcgttccaat
    13801 atgtgtacgt tggaatgtta gtgcttatat ggggggaaca gaatcctctc ttgattgaag
    13861 acaagttagc cattaggctg gtttgtctct ttgtcaactg tagtgggttg atataatagt
    13921 attagtgagt gggataaaag tttcatttag tttattcagt acaaatttaa cgggtcaaga
    13981 tttattgaac tgcaccccaa tagttagaca gaa
//
LOCUS       DBERCW010000045        13963 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.045, whole genome shotgun sequence.
ACCESSION   DBERCW010000045 DBERCW010000000
VERSION     DBERCW010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.045"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..290)
                     /locus_tag="ACL72M_001793"
                     /pseudo
     CDS             complement(1..290)
                     /locus_tag="ACL72M_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(352..801)
                     /locus_tag="ACL72M_001794"
     CDS             complement(352..801)
                     /locus_tag="ACL72M_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS0716877.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(803..1561)
                     /locus_tag="ACL72M_001795"
     CDS             complement(803..1561)
                     /locus_tag="ACL72M_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS0716878.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1676..3655)
                     /gene="stkP"
                     /locus_tag="ACL72M_001796"
     CDS             complement(1676..3655)
                     /gene="stkP"
                     /locus_tag="ACL72M_001796"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGS0716879.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3652..4392)
                     /locus_tag="ACL72M_001797"
     CDS             complement(3652..4392)
                     /locus_tag="ACL72M_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGS0716880.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(4407..5720)
                     /gene="rsmB"
                     /locus_tag="ACL72M_001798"
     CDS             complement(4407..5720)
                     /gene="rsmB"
                     /locus_tag="ACL72M_001798"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGS0716881.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5713..6648)
                     /gene="fmt"
                     /locus_tag="ACL72M_001799"
     CDS             complement(5713..6648)
                     /gene="fmt"
                     /locus_tag="ACL72M_001799"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGS0716882.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6661..9057)
                     /locus_tag="ACL72M_001800"
     CDS             complement(6661..9057)
                     /locus_tag="ACL72M_001800"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGS0716883.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHARDVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9123..9437)
                     /gene="rpoZ"
                     /locus_tag="ACL72M_001801"
     CDS             complement(9123..9437)
                     /gene="rpoZ"
                     /locus_tag="ACL72M_001801"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGS0716884.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9462..10088)
                     /gene="gmk"
                     /locus_tag="ACL72M_001802"
     CDS             complement(9462..10088)
                     /gene="gmk"
                     /locus_tag="ACL72M_001802"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGS0716885.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10218..11831)
                     /locus_tag="ACL72M_001803"
     CDS             complement(10218..11831)
                     /locus_tag="ACL72M_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGS0716886.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11913..12182)
                     /locus_tag="ACL72M_001804"
                     /pseudo
     CDS             complement(11913..12182)
                     /locus_tag="ACL72M_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004027196.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(12314..13072)
                     /locus_tag="ACL72M_001805"
     CDS             complement(12314..13072)
                     /locus_tag="ACL72M_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716887.1"
                     /translation="MKFKNYLFDLYPYFPKGFSLDNREDPDVCSKALYDDLCKMFFDD
                     DSKEKLKITSVCNKCQNYGNRDYYTLFIDKDKYLLSSDYIGASIYWAQEAGLNDRIIL
                     DHLSISRTIGGHILFPRGGKLETVNQARGGEKGYYDRFDLTLYAIKEWFVENKNTKIG
                     YAIENYHEWFELFSGDDNCKNGFENFVEFFKLEGFIYEQNKIIDLIKSDLENNQVVFL
                     DKEDILIASTEEEYIRYMKNLNIIILERTKKILL"
     gene            complement(13088..13228)
                     /locus_tag="ACL72M_001806"
     CDS             complement(13088..13228)
                     /locus_tag="ACL72M_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716888.1"
                     /translation="MLFYLTKELNSGVKKIGTISTTLVVVAGVSAGVLGGKFDFKFPK
                     KI"
     gene            complement(13182..13685)
                     /locus_tag="ACL72M_001807"
                     /pseudo
     CDS             complement(13182..13685)
                     /locus_tag="ACL72M_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370715.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
BASE COUNT         3839 a         3256 c         2598 g         4270 t
ORIGIN      
        1 gatatccaaa gaaacaattc tcccttgact tgtgacaatc gcttgagcct tcatagcgtg
       61 aaatttcttt ttaccagaat cattcgctaa ttgttttttt aggacaattg atttgtactt
      121 ccgtcgcatc aatcattacc gtgtcttcag aactgagagg agttcttgaa atcgtaacac
      181 cacctttgaa caagagttac ttcaacccat tggctccgac ggagtaagtt gctttcgtgg
      241 ataccaaaat cagccgcaat ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt
      301 tgttaattta tttatctcat ttttcagaaa attcttttat ttctgtaaag tctacgatac
      361 tcgatgtgtt tttatataat gatacagtct gagaatcact gttccgctag ccattccaat
      421 agagattacc aaagccaaca tgacaaccaa ggtcgcactt gccagtgctt tattatagtc
      481 ccctgtcaca aaaaaggcag ttgttcggta ggagagataa cctggaacca gcggtgccaa
      541 aatggccaag ataaagacca cagcaggtgt cttataaaga atacttaaaa tctggctgac
      601 acaagaacca ataatggctg caatgaaggt agctacaatg acattggtcg gttccttgag
      661 caagagatag attagccaga cagtcatgcc caaaatccct ccaggtaaga gcatagaccg
      721 ttgcacattg agtacgatta aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa
      781 taaaaaggtt gttagtgtca tattagttca tcaataccaa ggcgacagaa gttcctgccc
      841 ctaaagcgag ggtaatgagc agggattcaa acatcttact cataccagag tttatgtggt
      901 tggtcataat atcacggacc gcattggtca aggcaatacc tggtacaaac ggcatgaccg
      961 caccagctat aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc caaaactggg
     1021 caattatccc aaagacaaag gctccagcaa aggctgtcac aaagggaatt cggataaatt
     1081 tttccacata gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt
     1141 cgtagatatt tccgctaaac ataactgaaa agaaaggagc actaaaggtc gcagccagag
     1201 ttacctgcaa cttagtatag ggaaggggtt tggcttgcaa ggccgtcaat tgcttaaagg
     1261 ctgtttctaa gtcaatctgc cccccaacta gctgacgaga aatctggttc acatcgcaga
     1321 ctttttcgat gttataagaa gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt
     1381 caatagagaa aaagatagcg gcaggcatgg caaggacatt gcaatccaca atcccctgcg
     1441 aatgcgcgat tcgaatcatg gtatcttcta cacgatggat ttctgagcca cttttaagga
     1501 gaatagtccc cgctagcata atcacatcaa tgacggcatt taattctttt gattcttcca
     1561 tgctttcctc cttttatcaa ctccctctat tctatcacaa atccggactc aaaaaaaatc
     1621 tttgccatga aatcatgaca aagattgatt actcattttg attatccatc tgcttttaag
     1681 gagtagctga agttgtttta ggtttgtaga ttgaaatctt gactctagtc ttatttaggt
     1741 ctaccttttc acctgctcta ggactttgtt caacaaccat gccttctaca ctacctgcag
     1801 gcgctgtcgt cacttctaca acttctatat tagcttcctt aatcccaaca atttgaatca
     1861 aattgttctt agtaaactcc aagctggaac caatgtaact cggcatggca acacttgtaa
     1921 cttttttagc tactgtcaag acaatttgag taggtttact cacatcataa gtcgttccgg
     1981 cacctggact ttgtttcata atcgttcctg gttcgctttc gctggactct tcttcctcta
     2041 tcttaatcaa attctcagga accttcttct gcttgagttc tgagattact tctgtagagt
     2101 tccgtccaat atagttccct aattgaatcg tcgtagcttt tttagctact gtcaaaacaa
     2161 tttgagttgc cttgctcaag tcataggtcg taccttctgg tagactttgc ttcaagaccg
     2221 ttccagcctc actctcattg gactcttctt cctcaatttt aatcaaatta tctggaactt
     2281 ttttctcttt taattccgcg ataacatcag aagatttccg gccgacataa ttactaattt
     2341 ggaaggattg tttgcctgat gagacaacca gattgatttt cgttccttct tttcgaccag
     2401 ttccagcgcc aggatctgta cggataatcc gcccttcttc caccttttca ctagcctctg
     2461 tcttctcctc accaatctca aaattggctt ttttgagcgt tgccttggcc tctgcaactg
     2521 tctgacctgc cacatccgga atggcaatgg ttgcaggagt tctggataag atccaaataa
     2581 gagaagctgc caccaataca aggctggcca acaaaatcag gtaacgcatc ttaaatctat
     2641 gttttttcgg tgcttgtggt tggtaagttt cctctgtcac agcctggctt gggtttttga
     2701 ttgatttgtg ttctgtctgc gcttgaacct taggaataga tgtcaaggta ctctgagaaa
     2761 ccttcggcaa ggtcttggta tctgccttgc tcgtttcatc aaagattaac ttactttcat
     2821 ttctacgatt gtaggacaag ctactagaca agtccacata catctctgaa accgatcggt
     2881 agcgattggt caacttttta gcagttgcct tgataataac attttctaaa gcctgaggta
     2941 cagatggatt ttctgcaata acggacggca ggggtttctg gaaatgctgg agggcaatgg
     3001 tcaccgcgct atccccgtca taagggatat ggcctgtcaa catctcatag aaaataatcc
     3061 ccatggcata gatatcactc tgcacagtcg ccttagaacc acgcgcctgc tctggtgaca
     3121 agtaatgaac tgagcccaac atcgagttag tctgggtcag acttgtctct gcaaaggcta
     3181 cagcaatccc aaagtctgtg accttggcag tcccatctgg tgtcaaaagg atattttgag
     3241 gtttcaagtc cctgtgaaca attcctcgag tatgggccaa gcgcatagcc aagagaattt
     3301 gtcccatgat acggacggct tcttcattag aaagaggata atgttccttg atatagcgtt
     3361 tgaggtctag tccagcaaca tactccattg caagatactg ttgaccgtct tcctcaccaa
     3421 tatctgttat ccgaacgata tgaggatggt ctagatctgc catagctctc gcttcacgct
     3481 gaaaacgagc tacagctatc gggtccgtct ggtagttggt cctcagaacc ttcactgcca
     3541 cttcttcccc atctaagatt aagtctttgg ctaggtaaac atccgccatg cctcctcgac
     3601 caatctgttt gacaatccga tagcgtccgg caaaaatctt gccgatttgg atcattcttc
     3661 atcctcctcg ttcatagaaa caagggcaac cgtaatgttg tctaaacctc ctgcattgtt
     3721 agcaaaacga acaagtgtct ccgttttatc tgctaaagga atatcactgg ttacaatatc
     3781 acgaatctca ctgcctgaaa tcatgttggt caagccgtca ctattgagca agagatagtc
     3841 acctgactca aggataactg tcccaaaatc aggctgaatt tcatcttttt gcccaataga
     3901 ctgggtgata atattttttt gcggatgagc ttctgcctct tctggtgtca attgaccagc
     3961 cttgagcaat tcattaacca aggaatgatc gctcgtcaac tgatggtatt cttctccacg
     4021 aatcaagccg atacgcgaat caccaatatg agcatagata gcctgattat caataatagc
     4081 aaggacttcc aaagtagttc ccatgcctct gtaagcttca tcctgaccaa gctggtgaat
     4141 cttttgattt tcaatttcta ggtaatgggc gaaccattca cgcacttcat tgactgtatc
     4201 gatctgggta tcaacccaag ctacacccag gtctgtgacc gccatttcac tagcgatatt
     4261 ccctgcacga tgacctccca tcccatcagc taaaataatc atggtacgtc cagctctatt
     4321 gacatagtgg ttgacatagt cttggttatt tgttcgtttc tgaccaacat ctgttaataa
     4381 tgaaatttcc atgtgtcagt tccttcctaa tccgatatct tgcgaaattg actgatgaag
     4441 aatccatcac ttccatacaa ttcaggtgta atgaggatac agccgtcttt catgatatcc
     4501 ttacattcat gttctagttt tacctgctcg aactcgggat gactctctaa aaaggcctta
     4561 acgacttgaa aattctcctc tgagacgata gtgcaggtgc tataagttat tataccacct
     4621 ttgcctagta tttgacaaac actacctaat atttctaact gaatttcctg caaggacgcg
     4681 aaatctgccg tttctttatt gtatttgata tctggttttc ggcgcaaaag accgattcct
     4741 gaacaaggag catccaccaa aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc
     4801 tttctggcat ccaatttttg agtttgaacc cgatcttcaa ctcccagacg ttgggcattt
     4861 tcttgaatta aatccaactt gtggtcgtac aagtccagag cagtaacctg acctgtcgta
     4921 agataagagg ctatatgggc tgttttccca cctggagccg cacaggcatc aagcactcgc
     4981 tcatcacctt gtaaatcaag cgtcggagca accagctgac tggactcgtc ttggatggta
     5041 atggctccat ccgcaaacaa attatgccct gcaaaatgcc cctgctcctt aaccagacca
     5101 gtggttgcta aaagggaatc attcgcctcc aacaaggctt ggatttcctc ttttcgactt
     5161 aggtctgtta cacgaatact ggctttgttt cgcactaaca ggctttcaaa gatggctttt
     5221 gctctctcct ctccgtattc ttccttgagt ttggcaacta gccaaactgg gagagaatag
     5281 gcaatggagt cacgcttgtt ttttcgcttg atgctagcaa tatctggcca gccttcacgc
     5341 aagatacggc gaaggagggc attgaccaat ttttcactgc cttttttacg aagtttggcc
     5401 aattccactg cttcattgac cacagcatga tctggaatct tgtccaaata gcggagttgg
     5461 taggcactca tgagaagaag gacatagagc cagctgtcta actggtctct gtcttcgata
     5521 aagtgggata ggtaccattc cagagtcagt ttacgggcta ccgttccata gaccagctcg
     5581 gtcactaagc ccttgtctgc tgccaaaagt tgactcccct ttagatgctt atttaaggcg
     5641 atatttgagt atgcttggtt cacaaaaaca tcctctagca ctgctagagc taaacttcta
     5701 gccgtttcta ctttagtcac caaatcgttc tcctacagtc aatgtacgtc caactccgtt
     5761 gaggaaggaa gcaatgtcca tcttaggctt accagctggc tgcacttgtt tgagggatag
     5821 agccccttca gccgttgcga caatcaattc tttcttgccg atagagagaa tctcacctgg
     5881 atttccctga ccttctactg gtagggcttc ataaatctta aagcggtcgc ccttaaggaa
     5941 agcatgggca acaggccagg ggttcattcc acgaatttgg ttaaagagtt gacgattggt
     6001 tttgttccag tccagttttt cttcctctgg ctttatattt ggagagaagg taacctgact
     6061 cgtatcctgc ggttcaggtt tgatatcacc agcaatatag gcaggcagag tgtccaaaag
     6121 caaatcacga ccaactagcg ccaatttttc aaacaaggtg ccaacattgt cctcatctgt
     6181 gatcggaatg ctgcgacgag aaatcatatc tcctgcatcc atttccttaa ccatttccat
     6241 gatggtcaca ccagcttcct catccccttg aatcaaggca taatggatag gcgcaccacc
     6301 acggtgtcta ggaaggaggg aggcatgaac gttgacagca aagtccatgc tatcaaggag
     6361 tttgcttggg agaaactgcc caaaagcagc agtcacaatt ccatctgctc ctagcttcat
     6421 aagttcttcc atctctggac ttccagataa tttttcaggt tggtagatag atagtcctgc
     6481 ttccttggca gcctgcttga ctggggtttc ttggataact tttttacgac caacagcacg
     6541 gtctggctgg gtcacaacgg ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa
     6601 gactgttgct gaaaagtcgg gggtccccat aaagattagt tttgtcatat cttctccttc
     6661 ttataaaaat tgctgcggct catggtcaat gctgagacgg agctcactat tttcccgttc
     6721 ttgagtcaag gccaagacct ggttgagggt cggccccagc tcatcttcta aacggtattt
     6781 aattaaaatc tggtaatgat agaggttgtg ggtacgggca atcggttttg gcgttggccc
     6841 cagaatggga ctggtctctg acaagcctga ccgcaaaatg ttcatgactt cataggcacg
     6901 tttgaaaacc tcttcttctt tcttgtgaga aagggtaata ccaatcgtga aatagtaagg
     6961 tggatagccg agttgtcgtc tgattcccat ttcataggca taaaagcctt cgtaatcttg
     7021 atccttggca aatcgaatag catagtgctg cgaattgtag gactgtatca agacttgacc
     7081 tgctttttca gcccgacctg ctcgacctgc cacctgagtc aagagctgga aggttctctc
     7141 agaagaacgg aaatcaggca gattcaaggc cgtatccgca tttagaactc cgactagggt
     7201 aacattggga aaatccaaac cctttgcaat catctgagta ccaagtaaaa tatccgcttc
     7261 ccctcgccca aactggtcaa gcaaggcttg gtgactgcct ttctttcgag tcgtatccac
     7321 atccatcctc aaaatgcgag cttggggaaa gagttctgct agctcatcat aagccttctg
     7381 agttcccgtc ccatagtaac gaatactgcg gctcttacag ttaggacaga cctgaggaat
     7441 atccttcgag aaaccacaat aatggcagtt catagtcttg gtatccatat gcaaggtcag
     7501 agaaatatcg cagttgggac aagtatccac cgtcccacac tcccgacaca tgacaaagct
     7561 agaataacca cggcgattga gcatgagaac cacctgctct tttttaacca gacggtcttg
     7621 gatagcctct agcaaaggag gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg
     7681 aaagtcaatc acttgaacct cagggattgt agccaaagga ttagcacgtt gggttagacg
     7741 taagtgttga tagacgcctt tgccagcacg tgcccggctc tctaagctcg gcgttgcaga
     7801 tccaagtacc agagttgctt gattatactg agcccgtaaa atagctacat ctctggcatg
     7861 gtaacgggga ttgctgtcct gcttataagc cacttcatgc tcttcatcaa taatcatgac
     7921 acccagattt ttcagaggag caaagatagc agatctggca ccaacaacaa cttgggcatc
     7981 gccacgctcc accttgcgcc attcatcata cttttcacca ttggataatc ctgagtgaag
     8041 aatggctacc ttgtccccaa aacgtgctat aaaacgctcg gtcatctgag gagtcaagga
     8101 aatctcaggt accagcaaaa tagctgtctt gcccttatcc agggcacctt ggataatctg
     8161 caagtaaacc tcggtcttcc cacttcctgt aatcccttga agtagaaagg gaggttgaga
     8221 actgccaata gaactcacaa ccgcatcacg cgcctgtctt tgttctggat ttaactccaa
     8281 aggtctactt gcttcaattc cttcaaaata agcagccgag cgttgaactt ccttttggac
     8341 tatggtaaca gcaccttgat ccacaaagaa gttgacttgc tctcgcgagt aggactctaa
     8401 caagctagcc aaggaagcgc tctctggatg agacagcaga taatctctca gttccaactt
     8461 tttcttggca cgtgtagaaa tctcaacacc ttctaattga gcatggtcaa cctcatacca
     8521 agactgggtc ttgaccttct tttgatcgac tgcctgatat tccagaccaa gcaggccttt
     8581 tctagtcaaa cgcatcattt cagcttgctt ggcaaggtct agtgaagaaa aggctagcga
     8641 atcttctgaa ccaaacaggc gcactcgttc ttcctgactc aagccttcca gaggatagag
     8701 aatcttgtca tagctagaat tcagaaatcc tggaagcatg gccttgagga tagaaatttt
     8761 gtaggagaag acagatttgc gtaactcctc agccagccag agttgttctg gcgtgagaac
     8821 aggagaaaaa tccagcacct ctgcaatatc ttttaaatct tgctccatct cttctccatc
     8881 tgattgggac tccaaaccaa gaacaatccc ttgaatcagg cgattcccct taccaaaagg
     8941 cacatgaacc cgcatcccaa cttccagcat tccctcaaat tcctccggaa tcctgtaact
     9001 atagggctgg tccgtctgca tcaagggcac atctacgata atcttagcta gggccatcgt
     9061 ctcacctcct ccttgtcagt acattcttgc aatagaaaaa ataagattga gtccccccaa
     9121 ccttaaattt tttcaccatc ttctttttct ttagcaattt gctctttgat tttcttttct
     9181 tcttcttctt tgcggcgttt ttcttcttcg atacggcgac gcactgcttc acgttttcct
     9241 tctggatctg ggtgaattgt aacgtttcct gattcgattt cttctaaagc gcgaagagtt
     9301 gatttttcag acttaaaacc ttgagttgct ggggcacctg cttccaattc gtgggcacgt
     9361 tttgcttcca agattacgag tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata
     9421 gagggtttta acatcatttg cttgtaccta ttttctaaat tttatcgggt agttggagat
     9481 tttggtaaca tctcctgata gtgaccaatg acacgatcca cacagaagtg ttctgcttca
     9541 atcacacatt tgacacgttc agcagctagg ggtacctgat cgttgacaat cgcataatca
     9601 tactcacgca tgagggcaat ttcttccttg gccttttcga ttcgttgggc aatcacttct
     9661 gcactatctg ttccacgacc taccaagcga tcttgcaatt catccaaatc tggtggtgtc
     9721 aggaagataa agacagcatc tggaaccttt ttcttgacct gaagagcacc ctgaacttca
     9781 atttcaagga aaacatcgat tcccttgtcc aaggtttcat tgacataggt cagaggagtt
     9841 ccatagtagt tgccgacata ttctgcgtat tccaacatct gtccttgacg aatcagctct
     9901 tcaaattctt cacgagtacg gaagaaatag tcaacaccgt ccacttctcc aggacgttgt
     9961 gcgcgtgtcg tcatcgatac agaatattga aattggtttt cagaactctc aaaaatctct
    10021 cttctaaccg ttccttttcc aacccctgaa ggaccagaaa aaacgattag taagcctcgg
    10081 tctgccattg tgtctccttt tagtcaatct gtgaaataac atttctctag aataatggca
    10141 aaaagccaga ttatccttta cagtctttct atctagtgta acaaaaaagc agtaattttt
    10201 caactgctct ttcttattta tttagcataa tctactgcac gaagctcgcg aatcacggtt
    10261 accttgatat ttcctggata atcgagattg ttttcaattt tcttacgaac tttgtgagcc
    10321 aagattgtga ctttgtcgtc cttgattttt cctggattga ccatgatacg aatttcacgt
    10381 cctgcttgaa gggcaaagct agtttgcact ccttcaaagc cgttagcaat ttcttccaaa
    10441 tcatggagac gcttgatgta gctttcaaga gactcactac gagcacctgg acgggctgcg
    10501 ctcaaggcat ctgctgcagc gacgataact gctatcacgc tctcagcttc aacatctccg
    10561 tggtgactag caatcgtatt caccacaact gggggttcct tgtacttacg ggccaattcc
    10621 ataccgattt caacgtggct accttcaacc tcatggtcaa tggctttccc gatatcgtga
    10681 aggaatccag cacgacgggc aagagccgca ttttcaccaa gttcgctcgc catgatacca
    10741 gccaacttag caacctcaat cgaatggcgc aaaacatttt gtccatatga agtacggaac
    10801 tgcaaacgtc ccataatctt catcaagtct ggatgaaggt ttggcgcacc aatttcatag
    10861 gcagcagcct caccgtattc acgaatctta ttgtcaatct cttgacggtt tttctcaacc
    10921 aactcttcga tacgagctgg atgtatacga ccatctttga gcaacatttc catagtcata
    10981 cgggcaatct cacgacgaat cggatcaaat cctgacaagg tcaccacttc tggtgtatcg
    11041 tcgataatca catcgacccc tgtcaaactt tcaaaggtac gaatgttacg accttcacga
    11101 ccaataatgc gtcccttcat agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc
    11161 gctacatatt caccagcgat acgttgcata gcttgaacca agatgtcctt ggccattttg
    11221 tcagaacgtt ccttgacctc ttgctcagct tcgcgaatgc gactggcaat ctccctggtc
    11281 aagttttcct ctgtctgagc caagataata tctcgtgctt ctgcctgaga cagagcacca
    11341 atacgctcta gttctgcttc tttttgtctt tcgacttcct ctaattgctc ttcacgcgca
    11401 tcaaggtttt tcgctctatc agaaatactt tgttcttttt gttcaagtgt ttgttcttta
    11461 ctcgtcaaat tgtcgtcctt acggtcaagg ctagtagctc tctctgtcaa acgactttcg
    11521 atttgtttga gttcttgacg ttctgatttg aattcagcgt ccacttcttc acggtatttt
    11581 ctggcttctt ctttggcctc caatagtgct tcttttttaa gagacttgct ttcacgtttg
    11641 gcttcattaa caagtaaatc cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct
    11701 tgttcagcat ttaaaagcat caactctgca gcttcctgag atgatttcat cttagctgag
    11761 atgctgacat atccaatgac taaaccaatg atgacggcaa aaacagcaat cgcaagcgac
    11821 atgatttcca tgtttttacc tcattttatt gttattccga atgacataca ttcttttaca
    11881 ttctaccata aaaaaagaat ttaaacaaac cttaaatgga tatcgctaac atccgcatta
    11941 tcactatcat agttatcatt tacagatata aagcgaatac ctttttcagg aaatatcttt
    12001 tgtaagtact ttcctgactc gatataatct ctgccgaaac gagataaatc ttttaccata
    12061 atgatagaaa actttccttt attcaggtca tcaatcatat tcttaaaatt tggtcgctca
    12121 aaattagaac cactatatcc atcatctaca tattcatagg ataattcaat agatttctct
    12181 tctacctcca aaaagcaaaa aggataaatt tcccctacac tttaatagtg aaaatttatc
    12241 cctcttggta agctctttta ttaatttttt tgataaagaa aacgcacatt ttatttaact
    12301 ggtgctgaaa tctttataat aaaatttttt tggttctttc tagaataatg atattaagat
    12361 ttttcatata tcttatatat tcttcttctg tgctagcaat caaaatatct tctttatcta
    12421 aaaagacaac ctgattgttc tctaaatctg atttaattaa atctataatt ttattttgct
    12481 catatataaa tccttctaac ttgaaaaact cgacaaagtt ctcaaatcca tttttacaat
    12541 tatcatcacc agaaaatagt tcaaaccatt catggtaatt ctctatagca taacctattt
    12601 ttgtattttt attttccaca aaccattctt ttatagcata tagtgttaaa tcaaaacgat
    12661 cataatatcc tttttctcca cctctagcct gattaacggt ttctaatttt ccacctctag
    12721 ggaaaagaat gtgtccacct attgttcttg aaatactcaa atgatctaaa attattctgt
    12781 cgtttaatcc tgcctcttgt gcccaataaa tagaggctcc tatataatca cttgataata
    12841 aatacttatc cttatcaata aataaagtat aataatctct atttccatag ttttggcatt
    12901 tattacatac agatgttatt ttaagttttt cttttgaatc atcatcaaaa aacatcttac
    12961 ataaatcatc gtacaacgcc ttactacata catcaggatc ctctctatta tctaatgaaa
    13021 aacctttggg aaaataagga tataaatcaa atagataatt tttaaacttc atatttatta
    13081 ttctccatta aatcttttta ggaaatttaa agtcaaattt tcctccaagc acacccgcac
    13141 ttactcccgc aactactaca agtgttgtac taattgttcc tattttcttc acgccactgt
    13201 ttagctcttt tgttaaataa aacaacattg atcatatctg cttcacttac atacttgtaa
    13261 gacaactgtt cgttggtaag atcttttaag agatattctt tgattgcatc tgtatgaatt
    13321 ttgtagttaa tcttagaaat ttctctattc aaattccagc ctaatgatag cttagaattt
    13381 taatctgact taagtctttt gtaatcctga attacataca tcttaaattc agcagaaata
    13441 cataaagcaa attcaaaggc aatatctgta tgtgcaaatg caccaccata tcttccacct
    13501 tttgagataa ttccgattgc tccagttttc tctacccatt tcttaggaga caatgtaaat
    13561 gaattatatc cagcttccga tttaattcgg tcgaattcga ccgaattgaa attcatgtta
    13621 tttaagcttt tccataaacc aagaaactca attgtatctt ttcttctcat ccaattttta
    13681 attacatcac tcgatactta tccgaacgat aagctccacg taaggtgttc gcaatcgacc
    13741 aaactgcatt gactacattt gaaatctgaa catcgttcga ctggaatatc ggtagttttt
    13801 ctttaaaatt agacatttgc ttcccctgtt tttatgattt acaattctct tcattatacc
    13861 acaaaatagg cgctttgtca actgtagtgg gttgaagtca gctaagctcg agaaaggaca
    13921 aatttcgtcc tttctttttt gatgttcaaa gcgataaaaa tcc
//
LOCUS       DBERCW010000046        13526 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.046, whole genome shotgun sequence.
ACCESSION   DBERCW010000046 DBERCW010000000
VERSION     DBERCW010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.046"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(778..1647)
                     /gene="gla"
                     /locus_tag="ACL72M_001808"
     CDS             complement(778..1647)
                     /gene="gla"
                     /locus_tag="ACL72M_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGS0716889.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIVA
                     AIAAVAVFKFLYL"
     gene            complement(1871..2392)
                     /locus_tag="ACL72M_001809"
     CDS             complement(1871..2392)
                     /locus_tag="ACL72M_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS0716890.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAS
                     LGLGFFKKKEDEK"
     gene            complement(2350..3456)
                     /locus_tag="ACL72M_001810"
     CDS             complement(2350..3456)
                     /locus_tag="ACL72M_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGS0716891.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVVVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGCLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(3567..3821)
                     /locus_tag="ACL72M_001811"
     CDS             complement(3567..3821)
                     /locus_tag="ACL72M_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716892.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(4161..5006)
                     /locus_tag="ACL72M_001812"
                     /pseudo
     CDS             complement(4161..5006)
                     /locus_tag="ACL72M_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            5240..6958
                     /locus_tag="ACL72M_001813"
     CDS             5240..6958
                     /locus_tag="ACL72M_001813"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGS0716893.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            7069..7416
                     /locus_tag="ACL72M_001814"
     CDS             7069..7416
                     /locus_tag="ACL72M_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS0716894.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(7695..8531)
                     /locus_tag="ACL72M_001815"
     CDS             complement(7695..8531)
                     /locus_tag="ACL72M_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0716895.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(8544..9173)
                     /locus_tag="ACL72M_001816"
     CDS             complement(8544..9173)
                     /locus_tag="ACL72M_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0716896.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(9183..9824)
                     /locus_tag="ACL72M_001817"
     CDS             complement(9183..9824)
                     /locus_tag="ACL72M_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0716897.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(9970..11199)
                     /locus_tag="ACL72M_001818"
     CDS             complement(9970..11199)
                     /locus_tag="ACL72M_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGS0716898.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(11189..12355)
                     /locus_tag="ACL72M_001819"
     CDS             complement(11189..12355)
                     /locus_tag="ACL72M_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGS0716899.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVIFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            12499..13512
                     /locus_tag="ACL72M_001820"
     CDS             12499..13512
                     /locus_tag="ACL72M_001820"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGS0716900.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNEFHVPEAVCIR
                     FAP"
BASE COUNT         4123 a         2907 c         2379 g         4117 t
ORIGIN      
        1 taaaaattta actaattaat agaaagtact aaatagactt atccttcaag gagttttcag
       61 cattatccat ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg
      121 aaacaagaat agagcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
      181 gtagatgtgt actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca
      241 acctgcggct agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa
      301 aacgataaca atcataggac tcagcagagt caatgtaggt cgaagaatac ccccctaatc
      361 gcttatttta tagcaaaatg aaatagaaac tgaacatttt gttgaggaag gtaaatcaat
      421 tcctcacaat gtttgagaaa gaagggagga ctattccaac ttcaacccac tataaagcag
      481 acttacaaga tagggaaccc atctccgata atatatagta gaatgaaaac tgcacaattt
      541 gattggagaa ttcaaaccaa tttctcacaa tgttttagaa acaagggtct attatttcaa
      601 ctgcaaccta ctatagtcca ttgaagctgg aatagcccac tgagacttct aaaccactgc
      661 tggagaggag tttgtttaga gtttctttca tttccctaaa aaatcaaaaa gagagaacca
      721 gtctgatcct ctcttattta tagatggtgc tcactcaaat gttaaaggag ctatttctta
      781 gagataaagg aatttgaata cagctactgc cgcaattgct gctacgatag gtgctactac
      841 tggtacccaa gaataccacc attttgaatc gcctttatgc tcaccaagaa ctgattttgg
      901 aaggaaagca tgaaggagac gtggtcccaa gtcacgggct gggttcaagg caggtcctgt
      961 aggtcctcca agtgatgtta ccaaagccat aacgaggaat ccaagtgcca agtgagccac
     1021 agaaagtcct gaagcagtgt gtggagccac ctgtgcttta atagccaagt cagaaaaatc
     1081 aactgtttgt cctgcttcta ttgccttttg tttcatgaat tgaagcactt cagcaccaaa
     1141 gaagttttta gtcaaaccaa gagctgcaaa gaacaaaaca aatgaaccaa caaactcatt
     1201 aatcaaacca ttgacagttg ctgcatagcg actttctttt gtaccatggt caatacttga
     1261 aatagttgag aaagttccca agatgttatt tgggttttca gttttcaagt agaatggacg
     1321 gtatgttgcc acaactaagg cttggccaaa gatagctccc aagacttgcg cgataatata
     1381 aggtaccact tgtgcccaag ggaaaagacc gctaactgca agccctagag tgaaagcagg
     1441 gttgatgtga ttcccagata cgttaccaaa catcaaggct gggatcataa cccccatacc
     1501 ataaccaaca gcgatgacga tccagccact ttggtgacct ttcgtacctt taagttcaac
     1561 gttggcaact gcaccattcc caagaatgat caaaatggca gttcccaaaa attcagtggc
     1621 atacttcagt gcccatgtga aatccatttg ctagattctc cttaaaattt tttagatatt
     1681 ccttatttta tcaattttta ccctatttag caactgattt ctggaaatat ttttaaaaaa
     1741 ataggattca tagtttccca gttcaacgga cttgtaagcg tttttattct tcacgaaaga
     1801 cctcgttctc aaaaccagga aaaaagccca catctgtgag cttttcctgg ttcctagatt
     1861 ctaaaatcta ttatttttca tcttcttttt tcttgaagaa tcctaatcct agactagcta
     1921 acaaggtcat gataccagca ctagccaagg tagcattagc ttctgtacct gtgtttggca
     1981 attcctctct cttacctgtc tcataagtcg gaacttctgg gtctggattc actggagttt
     2041 cagtttttgg agtacctggg tctggagttg gtttatctgg tgttgataaa cggtcatacc
     2101 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     2161 tatctggatc tttgtacttg tcaatcttac cagatacaac ctcgtcccag tttcctgttg
     2221 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     2281 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     2341 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     2401 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     2461 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     2521 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     2581 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     2641 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     2701 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     2761 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     2821 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     2881 atcatttttc aatgatagca aacacccttg ttcatcaaca tagcgaactt tcacattttc
     2941 tgagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     3001 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     3061 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     3121 acggtgactt tgagtgttta ctactactct ttcattattc tctgaaaata cttgtacggt
     3181 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     3241 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     3301 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     3361 ctcttcagaa ccagatctag cccaaccatt attaagggca tttgcttttg tatttgtatt
     3421 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     3481 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     3541 ttgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     3601 gtcttcagta gtttatatgc tctgtcatca tctttagctt tagaagcagc tgagtttagc
     3661 caagttgggg tattaggagt atctttatca gcctgtttca agacattatt caagtcattt
     3721 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     3781 gacttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     3841 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     3901 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     3961 tacgattttt aaactctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     4021 tcaaaccttt cttatacaag tcttcattct aaacgatttc ggctacacgg tgaatggttt
     4081 gattgtatac cgtcttctct taaccagcag tatccttagt tttaatgact actcgatagg
     4141 ttcctttaga accgttatag tcatctagtt ttaaaaaagc attccaaaca ttcaaaaata
     4201 gttggaactt cccttaataa atccgtcact ttctttttca agatagccca agcttgctca
     4261 ataggattca aatccggtga ataaggtggt agaggtaaga aaaagtgttt atcttggatg
     4321 cagagttcat ccaaaatgtt cttgggatga aaactagcat tgcccatgac aataacatga
     4381 ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact ccacaaagaa atcgcttgtc
     4441 atgcttttct tgtaaatcat gggagctata aactctccgt ctacttgtcc tgcaacaatt
     4501 gaagttcgct caaaacgacg tccgctaatc tttttataga ctttctcccc tctaggagcc
     4561 cgtgcataag gacgatagag gtagcggtcg attcctgttt catcaatata tacgattggt
     4621 aaatctttta ggttatccaa aatatcaaga aactcagcga ctttctctgg ctcttgttcc
     4681 ttaaagctcg tcatcttttt ttaaagtgac cttaatatac tttaaagctg cccatacgga
     4741 gggcagagca caatcaaaat gtgccgcaat ttcccgtaaa aaagcatctg gatgagcctc
     4801 tacaaaggct ttcaattcct ctaaaggaat ctttcggttt ttgacgactc gctttttcct
     4861 ctctatgtgt ccttgttcac atctttcttt tcccacgtga agagagttct gacgccaaca
     4921 ccaaaaaact tggctgcctc gacatggctg tgcccctctt tgatgtaatc taatgctcgc
     4981 tgtttaaaat cagtactata tgccatagct ttattataat atgcttgttt aaaactaagc
     5041 aactatatca atgttttgtt attagaagac ttactttttt tactgaaatc gaatttttcc
     5101 taacctcaac atcatataac cccaaaattc aatctgacct ggtttgaaga gatgttcgaa
     5161 gcagataagg ttttactaaa actaaaaaaa atgatataat caaactgatt aaatgtttta
     5221 aaaataaagg agaatttgaa tgtcttacca agaaaattac cagaaatggg ttgattttgt
     5281 ggagcttcct gactaccttc gtcaagattt ggaaaatatg gacgaaaaaa ctaaggaaga
     5341 tgccttctat acaaatcttg aatttggtac tgcaggtatg cgtggcttgg ttggtgctgg
     5401 tacaaaccgt atcaacatct acgttgttcg acaagctact gaaggattgg ctcgtttgat
     5461 tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca attgcctacg atagccgtca
     5521 cttctcacct gagtttgcct ttgaatctgc ggcagttctt gctaaacacg gcatcaaatc
     5581 ttacgtattt gaaagccttc gtccgactcc agaactatca tttgcagttc gtcatctcaa
     5641 ctgtttcgca ggtatcatgg tcacagccag ccacaaccct gctccattta acggttacaa
     5701 ggtttacggt gaagacggtg gacaaatgcc tccacacgat gcggacgctt tgactactta
     5761 tatccgtgca atcgaaaacc catttgcagt tgaagttgct gatgtggaaa ctgaaaaagc
     5821 ttctggcttg attgaagtta tcggcgaagc tgttgacgta gaatacctta aagaggttaa
     5881 ggacgtaaac atcaacccag ccttgattga agaatttggt aaagacatga agattgtcta
     5941 cacaccactt catggtactg gtgaaatgtt ggctcgtcgt gctcttgccc aagcaggatt
     6001 tgactctgtt caagttgttg aagcgcaagc aactgctgac ccagacttct caactgtaac
     6061 atctccaaac ccagaaagcc aagcagcctt tgcccttgct gaagaacttg gtcgtcaagt
     6121 tggtgcagat gttcttgtcg caactgaccc agacgctgac cgtgttggtg ttgaagttct
     6181 tcaaaaagat ggtagctacc tcaacctttc aggtaaccaa atcggtgcta tcatggctaa
     6241 atacatcttg gaagctcaca aaaacgctgg aactcttcct gaaaatgccg ctctctgcaa
     6301 atctatcgtt tcaactgact tggtaacgaa gattgctgaa agctacggcg caactatgtt
     6361 caacgtcttg acaggtttca aatttatcgc tgaaaaaatc caagaattcg aagaaaaaca
     6421 caaccacact tacatgatgg gatttgaaga aagcttcggt tacttgatta aaccatttgt
     6481 acgtgataaa gatgccatcc aagccgttct tgtcgttgct gaacttgctg cctactaccg
     6541 ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc tataaagaat atggctacta
     6601 cgcagaaaaa acaatctctg ttactctttc aggtgtcgat ggtgctgaac aaatcaaagc
     6661 gattatggct aaattccgca acaatgctcc aacagaatgg aacgcaacag ctatcactgt
     6721 cgtagaagac ttcaaggcac aaactgctac tgttgctgac ggtactgtta caaacttgac
     6781 aactcctcca agtgatgtgt tgaaatacac acttgctgac ggttcatgga ttgccgttcg
     6841 cccttcaggt acagaaccaa aaatcaagtt ctacattgca gttgtagggg aaaccaacga
     6901 agaatcacaa gctaagatta ctaacatcga agcagaaatc aatgcatttg taaaataaag
     6961 acctataaaa gatgagacca accaacctca tcttttttcg tatcaaatct aagcaatttt
     7021 agaaacttta tggcatacta gacttatcaa tgaaagcgag gtaatctcat ggaacaattt
     7081 ttagataaca tcaaagacct tgaagtcact acagttgtgc gtgcgcaaga agctcttgat
     7141 aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt gcccttactg ccgtaaattt
     7201 gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc acatttactt catcaatagt
     7261 gaagaaccaa gccaactcaa tgatttgcaa gcattccgct cacgttatgg aatcccaact
     7321 gtaccaggtt ttattcatat tacagatgga caaatcaacg tccgttgcga ctcttcaatg
     7381 tcagcacaag aaatcaaaga tttcgcagga ttgtaaaaaa tcagctaaca agtcttaaaa
     7441 tcacaaaaac gcataatgta aggtgcaaaa accttgatat tatgcgtttt attgttccta
     7501 aaacagttac atcagcattt cattacagaa cattttaatt ttggaagtca aatcaatttt
     7561 taacaatgtt ttagaaatca cagtgggcta ttccatattc aattatccag attcaatcgc
     7621 tattatcgtt ttcctagatt acaaaaaaaa ctacgttttg ctaatcaaaa cgtagtctca
     7681 gccactattt tatcttactg tccttctttt acttctttgg ttgctacatc ttctccaaac
     7741 catttttggc tgatttcttg gaacttgccg tccttgtaaa gactagaaaa agcttcattt
     7801 atcttcttaa ccaaggttgt atcttcctta cgggctccaa ccgcaaaagc ttctgtttct
     7861 agtccaactg taaagacatt ataatcgttt aaaacacctt ctgcttctaa ataatagttt
     7921 gcatagacac ggtcaatcaa tagaccatca attcgatcgt ttttcaaatc aatcaaggct
     7981 tcattaaagg tttggtattg attcgcttcc ttattagcga caatattctt caaaatttct
     8041 ggatttgctt caaagtccgc ataaccagat gaaccagctt gagctcctaa tgtctttcca
     8101 gtcatatcct ttgcagtcgt gataccagat gattttttcg taaccaatac ctgctcattc
     8161 ttcatatatg agttactgaa agccaccttt tcacggcgtt cgtctgtagc ggaatagcca
     8221 ttccaaatca gatcaatcgt tccttttgtc aattcagctt ctttcaaatc ccaatcaatc
     8281 ggttgccaat ttaccgtgat tccgtatttt tcaaaaacag ctgtagctaa atcaatatca
     8341 aatcctgcat aagaaccatc tttctgagca aatcccattg gaacaaaagt actatcaaat
     8401 ccaatagtaa tagacttgtt agactggtac tttgaccaat tatctccact agtttcgcta
     8461 gaatttttcc cacaagctac taagaacaaa gcagtcatca gactgactaa tacaagcatc
     8521 cattttttca tccatttttc ctcctattta ggttctactt tcaataatac atctgcgata
     8581 ttttcagcaa actgcaaatc atgggtaacc acaatctggg tcatcccaag ttccctattt
     8641 tgcaagatta gcttctccac ttccaaacgt aattctggat ccagggcaga agttggttca
     8701 tcgtagccaa tgatttctgg gtcaatcatc atagcacgcg ccaaagccac ccgctgcttt
     8761 tgcccaccag atagtgagaa aggataggcc tctgcgtgtc ctcctagtcc taactgttcc
     8821 aagagtccac tcgccttctt ctcagcctct tcctgcttca ttcccatggt cttcacaggc
     8881 gataaagtca aattttccag aactgataga tgaggaaata gttgaaaatc ttggaagaca
     8941 aatcctagta ggttgcgctt ctgcaattca tccagctcta aaggttgtcc attataaaag
     9001 atttgccctg aatcaatggt ttcaagaccc gcaagcatac gtaaaagagt cgtcttacct
     9061 ccaccagaag gtccaacgat agccaggatt tgcttttcag gaatacttag actgaaatta
     9121 gacaggattt gtttgtctcc aaagacttta ttgatatttc gtaattctaa catggcagcc
     9181 tcctatctat aataactata cttcttctca acttttttgg aaataattgt cacaatccca
     9241 atcaaaatca aataaatggc tcctgccaag aacataggaa ctagactagc atcgcggtta
     9301 gcagctgttc gactagccaa gataaggtct gaaattccga gagcatagac caaagaagta
     9361 tccttgacca aactcataac ttcattaaag acactaggaa gaacgatctt ggtcacttgg
     9421 ggcaagataa tatagcgcac tctgtcaaaa gggctaaact tcaagacctt ggcggcctca
     9481 tactgtcctc ttggaatagt gtcaattccc ccacggaaaa tttctgcaaa gtaagctgca
     9541 tagttgagaa caaaggcaat aatagctgca ggaaggcggt ctaaacgaat cccaatactt
     9601 gggagcacat aatagataaa aattagttgc aagagtaagg gggttcctcg cataacccag
     9661 atgtaaatgt taatcagata atggaggggc ttccaatgga cttgcaaggc aaaagcaatc
     9721 aaaacgccca agggaatcga aaatagcaag accagtgcaa agacctgtac agtcgtgctc
     9781 gcaccattca gtaaactcgg taatatctca aataaataag acatactgca cctcctaaaa
     9841 gtaattgttc ctattatagc atgaataaac aagattacca agtatttttg taaaaagatt
     9901 ctaccatata caaataaaaa ccgtagctat caaaagagat aaactacagt tctatatgtt
     9961 taaacattct tacaatctct caaacagttc ttgcatttgc acatcatctg gaaccagttt
    10021 taagtaagtg tgagcatgga cttttgcttc ttcaaaatgt cccaattcac gcaagagata
    10081 gatatagtgt tccagaaatt ctggattgtc cttcaaatct cctgtcaact cttgataatg
    10141 ctcataagca gtatccaaat cgtccatttc ttgataagaa cgagcaatca tccacttggt
    10201 caaaagattt tctggctcct cactctgcaa gtctagaata tcctcataac gctcctgctc
    10261 cagataaata gtggctaaac gaagcaagat ttcttctgta tcctcagcgt cttcttttgc
    10321 agcaagaaga taattttctg caccactagc atcatgcaat tcataagaaa attgtgaagc
    10381 agctagcaag aggcgagttt caaagggatt tttctctaat ccttgcttag cgatacgcag
    10441 ggcttcttga acttgatgtt ccttatgtaa agcctgactg tacccatact catagccttc
    10501 aaagtcagga gaaatggtat caagctgctt aaagtagagg gtggcttttt gatattcttc
    10561 ttgatcaaaa taaagactgg ccaactcaaa agctgttaag tcatcgtatt ctaactccag
    10621 ggctttttct aaaaactcag tagccgtttc aaatttccct aactgagcat aggcaaatcc
    10681 aattcgttga taggtggaaa tgcccgtttg ctcataaatc gagcgattat ctaactgggc
    10741 ataggcttga atagccgctt ggtaattttc caactcacta tccaactctg ccaaacccaa
    10801 catcaagaga gaatcctctg agtaggtcaa ggcctccaat aatttctcac gtgccacatc
    10861 tgtcaaacct tccagctggt aaaggtctgc cttcaaaacc aaagacgaga cataccagtc
    10921 actgtcagct tggatttcct caagataggt aaaggcttct tctatttgac catcctcgct
    10981 agcaattgca gctagattaa gatgaacctc tggaaaatcc tctacaattt tcaggtaaat
    11041 ttccttggcc tgaggataga aaccaatccc ttcaagataa gttgccaact catacagaag
    11101 atcacttgaa tcattttcta aagctttggc gaaataatac tcagccttag ttaaatcttg
    11161 ctcctccaaa gcctgtaaca tctgttgact attgttcact cttgacttcc tcaccctcta
    11221 attcatatag accactgact accttatacc attcgaaaat ggctgaaatg acaaccttag
    11281 cagaggcata aaccggaata ccaagtaaaa ctccccagat accaaacata gatcctgaag
    11341 ttaacaaaac aaagagaaca ttaatagggt ggatgtttaa ttgacttccc aaaatcaatg
    11401 gagagacaaa acggccttca atagtttgtt ctacgataaa gacaatcact actttcaaaa
    11461 gcatgactgg accagcaatc aaacccaata ctagagcagg aagcatggct agaaagctac
    11521 caagataagg gaccagattt aaaataccag cagtaacccc cagcgtaacc gcatagcgta
    11581 gaccaataat cttgaagaag atgataaata ttactgctac aataatagcc actgtcactt
    11641 gccctcgaac atagttggac aactgttgat tcacatctga taaaacttgt ccaacaggtt
    11701 ccttcaattt tcttggaatg aattgggtca aatagttacg caagcctttc ccatcacgca
    11761 agagataaaa gagcatgaaa ggaacgataa tcaaggcaac aatcacttga gaagctccac
    11821 taataaaggc actcacccag ttgactgcct gagatgaaac cttacttgcc aaaactgtag
    11881 cctggctaga aaaattggtc aaaacttgct ctaattgagg tctgaaatca tctggcaggt
    11941 gctgggctac caatccatta acaatcctat ctatatcttc taagtaaaca ggaacgtttc
    12001 ttgcaaaggt caaaacctga cgttgcagat ttggaatggc gactgccaag ccccaaatga
    12061 taaagagagc gatgataaca aagacaatag tgatagctat aacacgatta accttatgct
    12121 tctccatcca atcaacaata ggattcaaca aataatataa caaaccagac aaaatgactg
    12181 gcaacatcac aactgctaaa aaatctaaaa caggtgaaaa tagaaaacta atcttactta
    12241 aaataaaaag attcaatccc aataataagg ttactaaaaa taccgtaatt gccttgttat
    12301 ctaaaaacca cttgaaaaac caagataggc taaaatgttt ctctttttgc tccataaata
    12361 cttcctttct attgttctct cattatacca tttttgaaac aaaataactc ttttttaaag
    12421 tgcttacatc taattgaatg tctttaattt gcttgttttt gtgatataat agtcttatct
    12481 ttacacagag gtatagtaat gaaagaaact gtttattttg gaacttatac acgtcgtact
    12541 tctcaaggga tttacaaggc agactttgat acagaaactg gtcagctttc aaatctagaa
    12601 ctttttgcag ctgagccaag tccaacctac cttgcctttg accagcacca acatttatac
    12661 actgttggta gccaagacga taagggggga attgcagcct atcaaactga cgggactgtg
    12721 ttaaatcatg ttgttgaaga aggagctccc cactgttatg ttgctgtcga tgaaaagcgt
    12781 gatttggttt acgcagccaa ctatcacaag ggacaagtcc ttgtttataa acgccaggaa
    12841 gatggtagtc ttctacttag tgatatggat caacacagtg gccaaggtcc acatgaaaat
    12901 caagcttccc cccatgttca ctatacagat ttaacacctg accactatct agtgacctgc
    12961 gacttgggaa ctgaccaagt catcacctat gacctcgatc aagaaggaaa attatctaag
    13021 ctctatacct atcacagcaa gccaggagca ggctcacgcc atatcatttt ccataaccac
    13081 tataaaatcg cttatctcat ttgtgaactc aatagtacta tcgaagtttt aatctacgat
    13141 ggcgttggcg aatttgtacg tatgcaggtt atttcaactt taccagaagc ttacgaaggc
    13201 tttaatggaa ccgctgctat tcatctctct aaagacggta aatacctcta cgcttctaac
    13261 cgtggccatg attctatcgc agtatatacc atccttgcgg acggtagctt agagttatta
    13321 gaaatcgttc caacgcatgg tcagactcca cgtgattttg atttgacacc cgaccaaaaa
    13381 tttctcattg ttgtccatca agactctgac aatgcaactg tctttaaacg taattgtgac
    13441 aatggtcgtc tagcagaact ctccaacgaa ttccatgttc ccgaagcagt ctgcatccgt
    13501 tttgctcctt aaaacaccat aaaaaa
//
LOCUS       DBERCW010000047        13362 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.047, whole genome shotgun sequence.
ACCESSION   DBERCW010000047 DBERCW010000000
VERSION     DBERCW010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.047"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(98..610)
                     /locus_tag="ACL72M_001821"
     CDS             complement(98..610)
                     /locus_tag="ACL72M_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGS0716901.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(635..1210)
                     /locus_tag="ACL72M_001822"
     CDS             complement(635..1210)
                     /locus_tag="ACL72M_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGS0716902.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            complement(1220..1615)
                     /locus_tag="ACL72M_001823"
     CDS             complement(1220..1615)
                     /locus_tag="ACL72M_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGS0716903.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            complement(2091..2900)
                     /locus_tag="ACL72M_001824"
     CDS             complement(2091..2900)
                     /locus_tag="ACL72M_001824"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS0716904.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(2897..3457)
                     /locus_tag="ACL72M_001825"
                     /pseudo
     CDS             complement(2897..3457)
                     /locus_tag="ACL72M_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(3459..4670)
                     /locus_tag="ACL72M_001826"
     CDS             complement(3459..4670)
                     /locus_tag="ACL72M_001826"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGS0716905.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(4684..5367)
                     /gene="rpiA"
                     /locus_tag="ACL72M_001827"
     CDS             complement(4684..5367)
                     /gene="rpiA"
                     /locus_tag="ACL72M_001827"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGS0716906.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(5665..6504)
                     /locus_tag="ACL72M_001828"
     CDS             complement(5665..6504)
                     /locus_tag="ACL72M_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGS0716907.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
     gene            complement(6518..7339)
                     /locus_tag="ACL72M_001829"
     CDS             complement(6518..7339)
                     /locus_tag="ACL72M_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HGS0716908.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            complement(7476..8333)
                     /locus_tag="ACL72M_001830"
     CDS             complement(7476..8333)
                     /locus_tag="ACL72M_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGS0716909.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(8487..9221)
                     /locus_tag="ACL72M_001831"
     CDS             complement(8487..9221)
                     /locus_tag="ACL72M_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0716910.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(9221..9904)
                     /locus_tag="ACL72M_001832"
     CDS             complement(9221..9904)
                     /locus_tag="ACL72M_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0716911.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            10094..10324
                     /locus_tag="ACL72M_001833"
     CDS             10094..10324
                     /locus_tag="ACL72M_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGS0716912.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            10553..12811
                     /locus_tag="ACL72M_001834"
     CDS             10553..12811
                     /locus_tag="ACL72M_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS0716913.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(13018..>13362)
                     /locus_tag="ACL72M_001835"
     CDS             complement(13018..>13362)
                     /locus_tag="ACL72M_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0716914.1"
                     /translation="ISLVAGLTNGELIAPMTYEETMTSDFFEAWFQKFLLPTLTTPSV
                     IIMDNARFHRMGKLELLCEEFGYNFLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNT
                     FYEALLSCSCFN"
BASE COUNT         4020 a         2996 c         2396 g         3950 t
ORIGIN      
        1 aattttgttc tttcacagag agctacctga gttctattca agctcagata gtactttctt
       61 ataaactaga caaactaact gtcattgtac catcagatta caagacatca tcgtcactca
      121 ccttggaatt caatgtcgta ccccaatggg taattttacg gtggggttga gctaaaattg
      181 gtctgttttc atagattgtt tgccatctat tccatagtag gcccgtcttt ttctcaatct
      241 taactcgcag atttctcata ttttctttga ttgggaagtt gaggacaaaa cctgcagtct
      301 ggttgcaacc gtttccttcc caagaatgac tacgaacaac ttggtttcca tctttatcta
      361 ctggaacttc ttcccaagtt atggagtagc gggcaatgta agctccactg tgttgaattg
      421 tcaatgtttt atctttcaca ggagtctgac tgattggttg aactggctta gaaacttgtg
      481 tcgccgtttc agcattcgta gctataaagc ggaaaacttc aacttctgca agactgaggg
      541 cattatagcc ttctagccca atccgaacat agcgcgcttt tttatggtta atcgtaattt
      601 gtgctgacac atctttagga gatattatac gttttcactc aatttcttta ccagaactgt
      661 ctaaaagaat gacatcaaag tttgccaatc tatcctgggc agtgtctgtt cggttgtaaa
      721 tattgatttg gcgaatggtt tcttctttag ccaaatctac ttgccaccaa ggcttagatt
      781 ggaagtttgt atgagtgaca gaattgtgac catagttacc atcgactttg ccatccacag
      841 ctcttctagc atctcctccg aaagctgtcg aactttgagt aacctgtttt cctaaggcaa
      901 tattttccat tggttcagcg cttggttgac tagaagattg aggtagagcc tgtttcttaa
      961 agaatcgcac tttatccaat ttcggatcac gataaccatg tttatccaag gtagcttgtt
     1021 taccaatatt aaagttagga atatcattca ttggactttc aaaatagcca cgagaacggt
     1081 gtttaaagcg tgaattacct gtaaatgtaa caatatcacg attattatga atcaagggag
     1141 tcacaacatt gtcattatca accacataat gcttaatttt tccactaaca gctaatttac
     1201 gactttccaa accaacatct cagaaaccat tcttagcatc ccaaacagtt ctggaagtaa
     1261 tcactttagg agcactgaaa gttgtcactt tcctcaatac atggttataa aaatcaggat
     1321 atttttggta atcttcaacc gctgcaatct gagctaggta gcctccaaga gaatgacctg
     1381 tcatatacaa cttagtaata cttatatcct tggctaattc cccaacaacc ttgcggatgt
     1441 catccgcttg agctggctct gttatctcta cttttgactc ttcccttttg ttttcaagaa
     1501 cttcacttgc ttccggaagc gtttgaggag ctagtcttgg ctcctctcta agaggagttt
     1561 ctagttttgg agcatcattt tctgactctt tcaattcctc cttagaatct agcacaccta
     1621 ttaccacttc agttgttaca tcttgcttta cttcattggc tgaaattcca gctggagcta
     1681 gaaatcaaag ccgactacaa cagatacaac tccgatactt aattttttat gccaaagcgc
     1741 ataattcgtt gaccaatttt cattatttct tatctttctt ttcgtttatt tacaagcaga
     1801 ctcaagcgaa atctcattgt gctatatatg ataagactga gaaattcaga aagtcaattc
     1861 attctcatct ctccttatca tactagtctg cttggctagg aagctaatgc tagtatccta
     1921 gaatcttgtc tttcacaatg ctggctatca gatcagacac acctattctt ccgcttcttt
     1981 cagttataag agcaggaaga agctcatagt attcctctgt ttcttcttta atacggatag
     2041 gcagtcaatc ctgaaaagac agaggcactc ccccttttaa atcttttttc ttacaattca
     2101 gcaagaatcg ctttaagcaa gcctttaaaa tcacctttaa cacgttcagt cacttctaca
     2161 acttcttcgt gattgagttc ttcttggaaa ccagccgcaa agttagtgat acatgaaatt
     2221 cccagaactt tcaagccaga gtgggctgcc acgataactt caggaaccgt agacatacca
     2281 actgcatctg ctcccagtgt cttataggaa cgaatttctg ctggtgtttc ataagtcgga
     2341 ccagtaactc cgatatagac accttcatca agcttgatat taagtttttt agccacttca
     2401 tgggcagtag cacggtattc tggtgtgtag gccctagaca tatctgggaa acgtgggcca
     2461 aagtcatcca agttttcacc catcaatgga ttttgccccg tcatgttgat atggtctgag
     2521 atagccatca aggtaccagg accaaatccg ataccgccag ctgcattggt tacaataaca
     2581 ccttcacatc caagaacttt catcacacga actgggaaag tcaccacttc cagaggattc
     2641 ccttcataga aatggaaacg cccttgaaga gccaagacct tgcgacctgc cagttcacca
     2701 tataccaatt taccagcatg accgactact gttgaacggc cccagtttgg aatctcagca
     2761 tagtctacta caactggatt ttcgatttct tctgccaatt ctccaagtcc tgacccaagg
     2821 attagaccga actcaggggc tgcaattccc ttttctttca ggaaagtagc agtttcatgg
     2881 attttgttta aaaatgtcat tgtgtgtctc ctttattatt tttttagcat ttgaccaatt
     2941 ttgtcaaagg ttttagcatt acgaatagta atgtggcggt agaaaggcac ctcagcaagt
     3001 acttatgata ggcagtctta gaataggatt cttcagaaaa tttcccctag aaaatcccaa
     3061 gttttccaaa ataaagcact tcatctttca gctctaaact ttcaactgtc gcgatgactt
     3121 ggtccacatc caaaccctca gtgtaaaaga gaaaatcttt tcgtgccaaa tctctgctcc
     3181 accaagctgg tagattttca agttccgcct caaagtcctc tagactcagt aaagaaaagc
     3241 tctgaataaa tggataatgg actgcaaaga aagtctctag cttttcaacc aattgggctt
     3301 tggaatctat cgaagtaaag aaaatattgc cactgttgat gtagctctca accttttcca
     3361 gtcccaagtt tgtcaattct tgacgaagct ccgccatgac gaccttattc ttaccaccaa
     3421 cattgatacc tctcaccagc aaagcatagc gcgtcatctt ataccaattt atctaagaaa
     3481 ctttccccaa tcatagcagt ttccacacca aagttatcgg caacagtcgc tgaaatatct
     3541 gcaaaatgtc ctactggaat gagaccattt cctttaaagg cagggctata ggccaacaat
     3601 ggaatatatt cccgagtgtg atccgttcct gcatacgttg ggtcatttcc atggtccgca
     3661 gtaatcaaga gaaggtcatt ctctctcata gctgcgataa tttcaggtaa gcgttcatca
     3721 aactcatgca agcaatcacg gtaaccgtga gcattacgac gatggccgta aagggcatca
     3781 aagtcaacta ggtttgtgaa tgagaatcct ttttcaaact cagcaagtcc catagtcttc
     3841 aatagtgtat caattccatg actatttgac ttgttgtgac ccatgtcatg gttgatacca
     3901 gcaccgttaa agatatcgtt gattttaccc acagcataag tatcgatacc agcctcattc
     3961 aatttatcca aaacagttgg ggaaaatgga gatacagcca agtcacgacg gtttgccgta
     4021 cgagtgaagt tacctggttc acctacataa gggcgagcaa tgatgcgacc aagaagggca
     4081 ggacgctcaa gggtaatcga acgagcgtat tcacagatac ggtacaattc atccaaagga
     4141 ataatgtctt cgtgggcagc aatctgcaaa acagggtcag ctgaagtata gataatcaac
     4201 tctccagttt ccatctgacg tggtccaaaa tcatcgataa cagccgttcc tgaataaggt
     4261 ttgttggctt cacgaataac cttgcgtcct gagaattctt cgatttttgt caggatttct
     4321 tctgggaatc cgttccagaa agtatcgaaa ggctcagtaa tgttgagtcc catgatttcc
     4381 cagtgtccag tcatagtatc cttaccaaga gatacttcct ctaattttgt tgcatatcca
     4441 gttggattgc tttcagctgc tacagtctta agaggagttt cacgaggaat atttccaaga
     4501 cctattttag ccatgtttgg gacattcaaa ccaactgttt ttgaaatgtg tcccagtgtg
     4561 tcagaagctc catctggaac ccctgcattg acaaagttat tagcatctgg tgctgcaccg
     4621 attcctacag aatccagtac caccaaatga atacgattaa atttagacat cttatgcccc
     4681 cttctatttt cctttttttg aagttgaaat ctgaactcca tcccgtccag caacgatgac
     4741 cttatccacc atttggttga ataaaccatg ctccacaaca ccaacgacat ggtccaattc
     4801 ttgtccaaaa gcaattggat tttcaatgac atccaaggcg aggtcaatga taaaattctg
     4861 catatccgtc acaaaacgtt ggccgtcttt ttcacggaaa cttggtttgt agccagctcg
     4921 ttcaaaacga cgaaagacct gttctgcacc atactgaacc acttctactg gcaatttaaa
     4981 agcacctagt ttttcgacca gcttgctttc atccaccacc caaatgtatt cttttgatgg
     5041 tgtcgcaaca accttctcca tcagaagagc accaccacca cctttgattc cattaaactg
     5101 actatccact tcatctgcgc catcaactgt cacatcgaca aagtctactt ggtcaataga
     5161 tttgagtggg atattaaggc cttctgcctg tttagtggtc acactagaag tcgttacagc
     5221 tataatctgc aatccttctt ccttgatacg acgaccgatt tcttcgacaa aataataggc
     5281 agtcgagcct gttccaagtc caacgaccat tccatccttg acaaactcag cagccttgat
     5341 acctgccatt ttcttcagat tttccactca aacacctcca ttaaagagct acctctatta
     5401 taccatgtaa aggcttttat ttcatctaaa agtaccttta gaatactgct tatttatcct
     5461 tgaaattaaa tttttttaat aaaagcagaa ctctgacaaa tcactttaag tacggatgta
     5521 aaccaaatca actctaacaa aaatagattt acaagagtaa aaaaacgaac aaatttagtt
     5581 tcttagcgag aagaatacta aacgttcgtt ttttgtgaat taagaataat gatacaaatt
     5641 atcaatattt tttgtctaac tattttagac atatcttttc attactttag gaagacaatt
     5701 actaatctcc gttggcaaaa ccacatactg ttcttgagct agttcttggg ctatggctga
     5761 atgaagatgg gtcgctactg ccacacgttc gtaaagacta gcttgcttaa actggcctgc
     5821 aaatcctgca atcatcccag caagcgtatc tcccattccc ccagtcgcct gatagggacc
     5881 gccaacctgt aactggtaat aatctgattg gccagcttgc caaatacgag tagctgaacc
     5941 tttctccacc aaaattgttc cttgagggaa ggaagttagg gcactagccg ttgcatcttc
     6001 cttttgcttt tcaatcgtaa ttccagataa tttttcccat tctttttggt gaggagttag
     6061 gataagctgg cttgaggaaa atgacaaact tgtcctagca agaatggtca aggcacctcc
     6121 gtctacaatc aaaatctgat tttgtcttaa gccagcaaag acctgtttaa ctagatcttc
     6181 tccaaaagca tcgtctcgta aacccggccc cagcaagaca acttctgcct tctccaattg
     6241 ctcttttaac aactgctggt cttgaagaga aaaggccata gcctcaggta aatggctgtg
     6301 cagggctgga atattttccc tatctgttcc aacggtcacc aatcctgcac cgctttttac
     6361 agctgccaaa gcagccatga tgatggcacc accataagga taagttccac caagaaacag
     6421 cagacggcca tagtctcctt tatgactagt acgagaacgt tcaataataa ctttttctag
     6481 taaggcttga tcaatcactt tcatcgttct tcctcaacta tcctttatct gattgtttta
     6541 aaacaacttg atagactttc ttagtccact cttctaagtc ttctccagca tagtcaagat
     6601 aatgcaccct atcttgtatt ttagttggaa taatattttc aaattggctc ttattatgag
     6661 ttggaataat acaaatatac aactcactaa ataaattcaa catgtcctta atttttgcaa
     6721 catggtagcc atcaaaaata taaccagtaa ctttaatcaa atctgtatag ataaaatgaa
     6781 aactcactcc aggaataaac ttgtcttgta attctttctc tgaaggagct cgacctaata
     6841 aacgctccat cgctaatcga taaccagaac ttgtatttga ccaccctaac atgacataat
     6901 caaaataatc tatcggatcc gatgcagcat ttctactatc caaaaccaac tcttcagcat
     6961 ctcgcctaaa ggctttcaca gcagataaga gctgacctgt tttaaagata gaaatcgctg
     7021 catctatagt cgtagtatga ctacagtagt ctgaagtcac taacctctta tgtagatcat
     7081 aagtcgaggc tactctttta tctgtagggg taaatggtgg cagaaaggga tgctgacaga
     7141 tgtaatctaa aatttctttt tttaaacaag aatcagcaca ctcaatactt gtttgacgtt
     7201 tatgaagttt ttcgtaagct ataaatttag caattttttc taattcccac tcttgaatat
     7261 ttggataatc aattagtgct aggtagtata ttccatccca ttgtaaacta tattccctat
     7321 tataaatttt taaaatcatc taatcacctc actccattat acaacaaaaa ggaggcgcag
     7381 acctcctttt gtaatcttat atctaaaatt taatattcat ttctgccatt ttaaatatag
     7441 ctatagaaaa tacactctct tcagcgattt ttctcttatt ttctatccaa tgtccgaagt
     7501 gctgcttgat aagtttgctc catcagcata gtaatggtca tagggccgac acctccaggg
     7561 actggcgtaa tatagctagc aagtggggca actgcctcat aatccacatc cccacagagc
     7621 ttaccatttt catcacgatt catcccaacg tcaatgacta ccgcacctgg tttgacaaag
     7681 tcagcagtca caaacttggc acgaccgatt gcgaccacca gaatatctgc tttagcagcc
     7741 accttagcaa gattatgggt gcgtgagtgg gtcaaagtca ctgttgcatt cttggccaaa
     7801 agaagctgag ccatgggttt tccaacgata ttagaacgac cgatgacaac cgcattttta
     7861 ccttctaatt caatcccata ttcatgaaac atttccataa ttcctgcagg tgttgatgga
     7921 atcatgactg gatgtccaga ccaaaggcgt cccatattta gaggatggaa accatccaca
     7981 tccttttctg ggtcaatagc caatagaacc gcctcttcat caatgtgttt tggtaatggc
     8041 aactgaacca aaatcccatg ccaagctgga tcctgattgt atttagcaat caggtctaac
     8101 aattcctctt gagtaatggt ctctggaact cgcactactt cgctacggga accagccgca
     8161 agagctgacc tctccttgtt gcgaacgtag acttggctgg ctggattatc cccaaccaaa
     8221 atcactacca aaccaggcac tagagctgtt tcttccttta attttgcagt cttttcagcc
     8281 aactgcccct gcaatttggc cgctaaagct ttcccatcaa taatctgtgt catatcactt
     8341 ctcttttctt tcaaatatct tccattatac caaaaactgc tagtgccctc taacacttct
     8401 ttcctaggtt atcctatagt ttcaaactat aagaaaaagc tctggttgaa cttttcacta
     8461 atcttgtctt gaaattttaa aatagattat aaaaccttac tcaagaaatc tttagtccgt
     8521 tgttcttggg tttgttcaaa aatctgctca ggtgtcccat cttcaacaac cacaccgtct
     8581 gccataaaga taacacgatc tgccacctca cgggcaaatc ccatctcatg tgttacgata
     8641 accatagtca tccctgactt ggcaaggtct tgcataacag ccaatacctc acctaccatt
     8701 tcaggatcca aggctgaagt tggttcgtca aagagcaaaa catctggttc catagccaac
     8761 ccacgcgcga tggcaatccg ttgttgctgc ccacccgaca gactctgtgg ataagcgtct
     8821 gccttatctg gcaaaccaac tttttccaaa agctcttggg ctctcttctc agcaacttcc
     8881 ctgctttcac ctttagtctt gataggtgac aaggtaatat tttccatcac agtcatatta
     8941 ggaaagaggt taaattgttg gaaaaccatg cccatcttct cacgcatggc aaacaggtca
     9001 ttcttcttgt ccgtaatatc gactccctca aagataagct tccccttggt tgcttcctcc
     9061 aacaaattca tagagcgaag caaggtagat ttcccactcc ctgaaggacc gatgataacg
     9121 acaacttctc ctcttttaat ctcgaggttg atgcccttca atacttcatt ctttccaaaa
     9181 gatttatgta aattttcaat ttttatcaag gtttctgtca ttatttctta tctccttgtc
     9241 ccatatgttt ttcaaaagct ttcaaggcta ctgtcagaat agaggtcata atcaagtagt
     9301 aaaatgctgc aaataaaagt ggtgttaaag gtagataggt tgttgtagaa actgttgtag
     9361 ccccattcca caactccatg accccaatag ctgataagag ggagctgtcc ttgataatgg
     9421 tgataaattc gttccccaat gctggcaaga tatttttgac tgcttgtggc aaaatcacat
     9481 aacgcatcgc atttttaaga cgaatcccta gcgaataagc cgcctctagc tgaccttttg
     9541 gaaccgcatt gattccggca cgaacagtct ccgaaacata agcaccacta ttcatagaga
     9601 taatcaaaat ccctggaatc agacgcgaaa aatcaacacc taaaattcca atctgaatag
     9661 tcggagcatt gatatgcata agagcaaagg caatcataat ttgaaccatc atcggtgtcc
     9721 cacggaaaat ccaaacgtac aagttggcca accaaacaag cggtttaaac tttgaacgtt
     9781 gcccaaaagc caagacaaca cccaaaatag ttcccaaaaa gataacacag atagaaataa
     9841 gaatcgtcac aacagcccca tagttaaaat aaggtaaata cttaggtaaa aaagaaaaat
     9901 tcatagtcac actgctttct aaaatagaat actgtatgat tataacatgt tttgaattaa
     9961 aatttaaatt ttttatccaa tttatttaaa aatctttaaa ctagcagaat tagcgagaaa
    10021 tcttagtttt ttctagtcaa gttgccctcc tttatggtaa aatagtaacg ataagaaatg
    10081 aaggagaatc aaaatggaat cacatttggt tagaatcatc aaccgccttg aagcaatggc
    10141 aaacgatggc ggaaatttaa aacgtaattt tgaacgcgaa ggagttgttg ttgcagaagt
    10201 tgcgtacagc cacgacgaag aaaacggccc aatctttacc cttcgtgacg tagaagatcg
    10261 cgaaacgtat acgtttgata gcattgactt aatcgcaatg gaaatttacg aacttctcta
    10321 ctaatctaaa acaagttggg attgtccctg catgtctaag taaaatcctt tttgtctcac
    10381 aaataggatt tttttatagt ccaaattcac aaaaattttc attgtaacaa cttctcaaag
    10441 cttcaatctt tttacttgct ttacacccca atcctgttat aatgagagta tagaatttga
    10501 ctatttttga cctttaaaca agtcaggcta aagaaagaaa tgaggtagat gtatgctttg
    10561 tcaaaactgt aaaattaacg actcaacaat tcatctttac accaatctca atggaaaaca
    10621 aaaacaaatt gacctctgtc aaaactgcta taagattatc aaaacagatc ctaacaatag
    10681 cctcttcaaa ggtatgacgg atctgaacaa tcgtgacttc gatccctttg gtgatttctt
    10741 caatgatcta aacaatttca gaccttctag caatactcct cctattcccc caacccaatc
    10801 aggtggaggt tacggtggaa acggcggtta tggttcccaa aatcgtggat ctgctcaaac
    10861 tccgccacct agccaagaaa aaggcctgct ggaagaattt ggtattaatg taactgaaat
    10921 tgcccgtcgt ggagacattg accccgttat tgggcgcgac gatgagatta tccgtgtcat
    10981 cgagattctc aatcgtagaa ccaagaataa tcctgtcctt atcggtgaac ctggtgtcgg
    11041 aaaaacggcc gttgtcgaag gtctagctca gaaaattgtc gatggcgatg tgccacataa
    11101 actccaaggt aaacaagtca tccgtctgga tgtggttagc ttagttcaag gaacggggat
    11161 tcgaggacaa tttgaagaac gcatgcaaaa actcatggaa gaaattcgca aacgtgaaga
    11221 catcatcctc tttatcgatg aaatccatga aattgttggt gctggttctg cgagtgatgg
    11281 taatatggac gcaggaaata tcctcaagcc agcccttgct cgtggagaac tgcaactagt
    11341 cggtgctact accctcaatg aataccgtat cattgaaaag gatgctgccc tcgagcgtcg
    11401 tatgcagcct gttaaagtcg atgaaccaac ggtggatgaa acaatcacta ttctcaaagg
    11461 gattcaaaag aaatacgaag attaccacca cgttcaatat accgatgctg cgattgaagc
    11521 agctgcaact ctttccaatc gctacatcca agatcgcttc ttgcctgaca aggccattga
    11581 cctcctagat gaagctggtt ctaagatgaa cttgaccttg aattttgtgg atcctaaagt
    11641 aattgatcag cgcttgattg aggctgaaaa tctcaagtct caagctacac gagaagaaga
    11701 ttttgagaag gcggcctact tccgcgacca gattgccaag tataaggaaa tgcaaaagaa
    11761 aaagatcaca gaccaggata ctcctatcat cagcgagaaa actattgagc acattatcga
    11821 gcagaaaacc aatatccctg ttggtgattt gaaagagaaa gaacaatctc aactcatcca
    11881 tctagccgaa gatctcaagt ctcatgttat tggccaagat gatgcagtcg ataagattgc
    11941 caaggctatt cgccgtaatc gtgtcggact tggtacccct aaccgcccaa tcggaagctt
    12001 cctcttcgtt ggaccaactg gtgtcggtaa gacagaactt tccaaacaac tggctatcga
    12061 actttttggt tctgctgata gtatgattcg ctttgatatg agtgaataca tggaaaaaca
    12121 tagtgtggct aagttggtcg gcgctcctcc aggttatgtt ggctatgatg aggctggtca
    12181 attaactgaa aaagttcgcc acaatccgta ttctctcatc cttctcgatg aagtggaaaa
    12241 agctcaccca gatgttatgc acatgtttct tcaagtcttg gacgatggtc gtttgacaga
    12301 cgggcaagga cgcaccgtta gcttcaagga tgccatcatt atcatgacct caaatgcagg
    12361 tacaggaaag accgaagcta gcgttggatt tggtgctgct agagaaggac gtaccaattc
    12421 tgtcctcggt gaactcggta acttctttag cccagagttt atgaaccgtt ttgatggcat
    12481 tatcgaattt aaggctctca gcaaggataa cctccttcag attgtcgagc tcatgctagc
    12541 agatgttaac aagcgcctct ctagcaacaa cattcgtttg gatgtaactg acaaggtcaa
    12601 ggaaaagttg gttgacctag gttatgatcc aaaaatggga gcacgcccac ttcgtcggac
    12661 tattcaagac tatattgagg acacaatcac tgactactac cttgaaaatc caagcgaaaa
    12721 agatctcaaa gcagttatga ctagcaaggg aaacattcag attaaatctg ccaaaaaagc
    12781 tgaagttaaa agttctgaaa aagaaaaata aatcctatag aaaaggagta gaaaatgaaa
    12841 tttttctgct tcttttttta ctaaaataac tgtaatttct tgacagcttg ccctttgtcc
    12901 attatgatat atagtagact gaatctgaaa tagtacgaaa caattgctaa aacatttata
    12961 gaaattaatt ttactttccc aatcgatttg ttctcatctt atttcaatct gctatagtca
    13021 attgaaacaa gaacaagaca aaagagcctc ataaaaggta ttgcaacttg gtaatacctt
    13081 tttgaggtgc tttttgatat gagcccatgt tttctcaata ggattgtact caggtgagta
    13141 gggaggaaga ggtaaaaagt tatacccaaa ctcttcacac aagagttcta acttacccat
    13201 tctatggaat cttgcattat ccataataat aaccgatggt gtggttaatg ttggtaagag
    13261 aaacttctga aaccaagctt caaaaaagtc gctcgtcatc gtctcttcgt aagtcattgg
    13321 agcgattaac tcaccatttg ttagacctgc aaccaaagaa at
//
LOCUS       DBERCW010000048        12651 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.048, whole genome shotgun sequence.
ACCESSION   DBERCW010000048 DBERCW010000000
VERSION     DBERCW010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.048"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(128..1225)
                     /locus_tag="ACL72M_001836"
     CDS             complement(128..1225)
                     /locus_tag="ACL72M_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS0716915.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLSYILAQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNLSIAQQNFGRVPIRIETN"
     gene            complement(1235..1975)
                     /locus_tag="ACL72M_001837"
     CDS             complement(1235..1975)
                     /locus_tag="ACL72M_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0716916.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(2295..2648)
                     /gene="rsfS"
                     /locus_tag="ACL72M_001838"
     CDS             complement(2295..2648)
                     /gene="rsfS"
                     /locus_tag="ACL72M_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGS0716917.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(2661..3161)
                     /locus_tag="ACL72M_001839"
     CDS             complement(2661..3161)
                     /locus_tag="ACL72M_001839"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS0716918.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(3162..3755)
                     /gene="yqeK"
                     /locus_tag="ACL72M_001840"
     CDS             complement(3162..3755)
                     /gene="yqeK"
                     /locus_tag="ACL72M_001840"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGS0716919.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(3755..4384)
                     /locus_tag="ACL72M_001841"
     CDS             complement(3755..4384)
                     /locus_tag="ACL72M_001841"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGS0716920.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(4436..4747)
                     /gene="yhbY"
                     /locus_tag="ACL72M_001842"
     CDS             complement(4436..4747)
                     /gene="yhbY"
                     /locus_tag="ACL72M_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGS0716921.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(4961..6067)
                     /gene="yqeH"
                     /locus_tag="ACL72M_001843"
     CDS             complement(4961..6067)
                     /gene="yqeH"
                     /locus_tag="ACL72M_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGS0716922.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFITGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(6070..6597)
                     /locus_tag="ACL72M_001844"
     CDS             complement(6070..6597)
                     /locus_tag="ACL72M_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGS0716923.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            complement(6612..7520)
                     /locus_tag="ACL72M_001845"
     CDS             complement(6612..7520)
                     /locus_tag="ACL72M_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS0716924.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDKPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(7577..8137)
                     /locus_tag="ACL72M_001846"
     CDS             complement(7577..8137)
                     /locus_tag="ACL72M_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGS0716925.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            8276..9485
                     /gene="sstT"
                     /locus_tag="ACL72M_001847"
                     /pseudo
     CDS             8276..9485
                     /gene="sstT"
                     /locus_tag="ACL72M_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            9553..10506
                     /locus_tag="ACL72M_001848"
     CDS             9553..10506
                     /locus_tag="ACL72M_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS0716926.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            10649..11029
                     /locus_tag="ACL72M_001849"
     CDS             10649..11029
                     /locus_tag="ACL72M_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS0716927.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETVAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKILASLQKTVEESLEAGLDFLI"
     gene            11128..11349
                     /locus_tag="ACL72M_001850"
     CDS             11128..11349
                     /locus_tag="ACL72M_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS0716928.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            11366..11680
                     /gene="trxA"
                     /locus_tag="ACL72M_001851"
     CDS             11366..11680
                     /gene="trxA"
                     /locus_tag="ACL72M_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS0716929.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            11985..12518
                     /gene="queF"
                     /locus_tag="ACL72M_001852"
     CDS             11985..12518
                     /gene="queF"
                     /locus_tag="ACL72M_001852"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGS0716930.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         3521 a         2876 c         2503 g         3751 t
ORIGIN      
        1 agagcaaact aggaaactag ccgcaggctg tacttgagta cggcaaggcg acgttgacgc
       61 gatttgaatt tgattttcga agagtattat tcgtaaaaaa tctcaaaaag tccacctttc
      121 ggtagactta gtttgtttct attctaatcg gcactcttcc aaaattctgt tgtgctatac
      181 ttagatttcc tagttggtaa atctggtctg ctttttgggt catagcatcc caaggttctt
      241 tgccaattcg gctgactaga ctgacctgac ctttcaaaga cttgagatgt tgcctgcctt
      301 tttcagtaaa tccaaggaca tgaatggctt ctggcaagac attttctcta gcctgcgcca
      361 agatatagga caagaggcgt ctgacacgcg ccttggtgta acgtttggta gtcactaact
      421 cgaccaattc ttccacagac tgggctgttt taatagcttc tttaatgcgc acagccattt
      481 cttgattgac ctgatagatg gtggttaggt cgggatttga caagatttga tagcggagca
      541 agggaaaata gtcttcccag atcaccttac tggcctgctc aaatagggca acagaaggca
      601 taaaacgttc taagaaatct tggtccttct gatgttgacg gagggctgtc gccgaggcaa
      661 agtccacatc tttattcaca gaatggtaac ctgccccctg acgctgaatc ggatgcagct
      721 tgatattccg tcctgcaacc gccttggcat aggccagagc aagaacatga ttgggggtat
      781 tacctgaaaa atcaagacca gcaaattcct tccacatagc ttgggttttc tggggatagg
      841 aaagggaatc aggcagattt tccacaaatt tctccatctc agtacctttc tctgtgtata
      901 agtcagcgat tttctgataa tctcgaactt cctctgtccc aaaaactaga ctatcaatgc
      961 ccaagcgatc caagatatcc acagctcctt gaccaaagaa atcagctgcc tgaacactga
     1021 ctaaaaaggg caattccact accaagtctg cgccattttc cagcgccatc tgggcccttg
     1081 tccacttatc cacaatagca ggctctccac gctgcatgaa attccctgac atggcaacaa
     1141 ttttcagtcc ctctgcctga tccagcaggt atttatggcc attatgaaaa ggattgaact
     1201 ctgcgataat acctgtgatg gtcatgatgt tctcctactt ctgcgccaca aaaaaccaac
     1261 gggtgctagt ttctgttggc tccttatcct caaagtctgc atagagtttg aaggacttaa
     1321 atccagcctg ttccagcaag atatcatagg tcaagatctc ataggtcctc tcctcatgta
     1381 cttcatcgtg gcgactaaag gaaccgtcag cctccttgat aaagaaagtc agctcatgca
     1441 cgatggagtg aggagcttcg tcctcatatg tatcccaaag catggcaaaa tcttccgcat
     1501 tttcatggta ggaatagcca gggaatactt catctgtctg gtaggtcgag tgcacgtcaa
     1561 agatgaaaac tccctcttca ttcagcgcat tgtacacgtc cttaaagacg tcccctactt
     1621 ccacctcatc ctgcatatag cagatagagt ccgaataaca cgtgacaaaa tcgtatttcc
     1681 ctgccttgga caaattcagc atattacctt ctataaaagc aatcttttgc ttggctgaag
     1741 ttgctctctt ctccgcaatc ttcaacatat ccgcactcaa gtcaagtcca gtcacatcaa
     1801 aaccagcctg agagaagcgc actgattgaa ttcctgtccc acaagccaat tccaagagtt
     1861 tctttctctc cttggtctta ggcaaatgac gcagagaaaa attcgtccat ttgtcgtata
     1921 aactatcgtc catgaccgca tcatagaccg ccgcaaaggt ttcataagtc gccataaaac
     1981 atgataccaa gtccgcccgt aattcgatag aaaattagga gccttacgat ggagccgagc
     2041 tccaaggaag gctatctatt ttccgagaat tacaggacgg gttcaaatcc tttctaagat
     2101 acaaagagcc ttaaaagcaa agagtacata ggaaactttc ttccctatcg tcagatacaa
     2161 agaaagttac tttttatctc agcttttagc tcgtgttcag tttcgaaatg aaacaaacac
     2221 gaggcccttt acctttctat caatttttct aaaataagca aagaaaccca gttgactaca
     2281 actgagttca tcttctaagc aagagcttct gaaatatcta ctgaattcgc ctcatgccat
     2341 agcttctcta gattataatg ggcacgcatt tcttctgaaa agatatgcac gacaacagca
     2401 ccgaggtcca gtaagaccca gcctccagct gcatcgcctt cgacatggct acctttaaag
     2461 cctgcttgag ctactttttc acggatatta gctgcgatag cgtccaactg acggctattc
     2521 attgagctag tgatgacaaa gtagtccgtc acactagtca aatcttgtac atcaagtgcg
     2581 aggatatcct ccgcacgttt ctcatcagcc gctttcacga ctagttctag taattctttt
     2641 tcgttcattt aatcctcttt ttagaaaata tgtttgtaat ctagaacatc tgcaaagcgc
     2701 tcctcccaaa tgtcctcata aaattcatta atcgtttctg ctggaatgtc atccccatca
     2761 aaggttgtga cagcaccttc tggaacaata agctgatagc catattcaaa ggcaaccttg
     2821 acagaggtat ccacacaata ttctgtctgc ataccacata aaactaattt ttcaatcccc
     2881 tgcttatcca agtattcttt taagccagtt tctttgaaaa tactgttata cttcttctga
     2941 aagacctttt cagcaggttt tcgatttaaa agcgcagata actgccaatc ttctgatgtt
     3001 tgagcttcag agttctcaat atgttgaaca tagataattt caatattctt gcttctagcc
     3061 tggttttgta aataagaaat tttttccaat agactttttg tctggaaccc agtttctact
     3121 aaaacattct gaacatcaat gattataaaa gccgtcttca tttagtcctc tttcaaatag
     3181 tgcacaaagg cgttataggt ttcaagggtt tggggataga tggggaatcc ctgatgagct
     3241 agatactcca cggtacgagc tgtttcgtag gccaccgcct tattgagcga tagacttgca
     3301 atctcacgcg ccacatccac tccaggaaat gcccgattgt gctcgatata gtctgcgacg
     3361 tagatgacct tatctaggtc tgtcatttga ccagctccga ctgtatgaat ttcaatggct
     3421 cgcagaattt cagaatcatg caaatccaaa tcttcctgaa ttttgtaaat tccgaccata
     3481 ccatgccaga cattgttgcc ccagtttttg aggtcagggt ctagctggta acggtcaatc
     3541 aaggctagaa attcctgatc tgacaacttt ttagcatagt catgaagaag acctgctaga
     3601 cttgctttct caacatctac accaaagcgc tgagctaatt ccatagcggc acgctccaca
     3661 cctagacaat gggttagacg tttctcaggt agaagctctg ccattttttc caacaaggcc
     3721 tcacgggagc agttgatata gtcttgatag gacatcagta gagcccctcc ttctcgatgt
     3781 agtctagcac tggctgaggt aggagaaagt tgggtttccg accttgggca aggaagtccc
     3841 gcaccatgct ggacgagata tccatgagcg gtacgtccac ccagataact ggataggaag
     3901 tccctacctt gtagcgtgga cgctgaaccc ccacaaactg aaccatgtca accagttcat
     3961 caattcggta ccacttaggc agatagtcaa ccatgtcggc accgatgata aagtaataat
     4021 ccgtatctgg attcttctct gtcaaaatct tcatggtgtc gtaggtgtag gaaataccct
     4081 tgcgctccaa ctcaatggtt tcaatgacta ggccgtcaat tccctcaatt gccaactcaa
     4141 gcatcttgag acgatggtgt tcagggatgg tttccttttt atcaacgtga ggaggttggt
     4201 attcaggcat gagcagaact tgatccagtc ccaactgttg ccgtacttga tccgcaacaa
     4261 taagatgggc attgtgaaca gggttaaaat tcccccctaa aatcccaact tgtttgcgtt
     4321 ttttctcctt gatttctggc tccaactcta ccttggtaaa gggagtcaat agttcgattg
     4381 tcataggcta gtccccttta tttctctatg aaaacagtta tttggagttt cggtcttaga
     4441 tttctttgac tttcttagaa atcttgcgat tttctttctt gctagattgt ttaaacaaaa
     4501 tcaagatgcg tcctattttt tggactgtat ccacaccgat ttcttcttcc aaaatttcag
     4561 ctacttcgtg gatgttttca tctgtgtttt gtaagagagt aaccttgatt aattcacgcg
     4621 catcaagagc ttgacggacg ctggttttga tttggtcgtt gagtccattt ttcccgattt
     4681 ggatgatagg tttgagggtg tgtgcctggc tgttgaggaa ggcacgttgt tttgatgtta
     4741 atgacataat tttcttcctt gttttttgat agttatttta ggtggtgagg gacggtcgga
     4801 actaattttc caaagatttc atctttgaaa aatggatttc ctgacctcac aattgagcct
     4861 tggtctcaat tgtgcccctt gccaatctac agattggcaa tcacaccacg gcaataacta
     4921 tcgctatatg agctcacttt gttcgctcag cgattttgtt ttaaataatt gcttttcgtg
     4981 tgacgacggc gacgccttct ggtgcccaga cggcgacttt tgctgtgcct gttacacgaa
     5041 tccagcctag gcctgagatg actaggtctg tcttatcttt aatggtaaag acatgctgga
     5101 ctagccttgg gaaatcttct ttttccttgc tatttggtgg tgtcagaaga gttcccaggt
     5161 gcttatcgta gaaagcacta gctccttcaa gcttgctacg atggagtttg agttcattgt
     5221 caaagaaagc agtaaatcct tgcttttctc ctgttataaa gtcaaagcgt cccaaaccac
     5281 ctaaaaatag ggtttgctca ggattaagct gataggtctt aggcttgatt tcctttttag
     5341 gactgacata cttgaggttt ttggccgtca aatagtgagc catctggtgg cggtggataa
     5401 ttcccggcgt atcgtaaata taagatccgt cgtcaagcgg aatctctatt ttgtccaagg
     5461 ttgtccctgg gaagcgtgaa gtagtgatga cattctgatc acccgtgatt tcttggataa
     5521 tagcattgat tagagttgat tttccaacgt tggtcacacc gaccacatag acatcgcggc
     5581 ccttacggta gtgttcaatc ttgtcaatga cttccttaat ggcatgttta ttttgtgctg
     5641 aagttaggac cacatcgact ggacgaagac cttcttcatg ggcacgtttc atgagccact
     5701 ggctaatctt accagactta actgacttag gaaggatatc ttttttattt cctaccaaga
     5761 ggacatcatt gcccgagacg aaacgtggta aacctgggat gacagatcca ttaaaatcaa
     5821 agatatcaat gacattgacc actaaagcat cactgtctcc cacctcgtgc aagagcttga
     5881 ggaaatcatc gttcgtcaac tggacatctg tgatttcatt gtagtggcgg agacggaaac
     5941 agcgttggca atagacttcg ccagtctcca aacctttttc aagtgccgac tggggggtaa
     6001 aaccaagacc agctttatct gtcgtctgaa tggttgctcc acaaccaata cagagaattt
     6061 cttccatagt taaattcctt ttttatatgt aatcggtccg tacttttcag tgatttttct
     6121 cataacacga cgctcacgag ttcggttaat ctgcgttttg attgagtcat gttggaccaa
     6181 gggtttgact aaaattgacc gaatccctgc acggtgggct gctcgtatat ctgtcatgag
     6241 ctggtcacca accatgacca cttccttttt gtcatagtgg aattccttca tggcacggtc
     6301 aataccaaat gtgaagggct tcaaggccca gtaaacgtaa tcaatcccaa atttctcaac
     6361 tgctcgttga acgcgttttt tggtgttatt tgacactacg ataatgccaa tacccgcgtc
     6421 ccgaaggtca tgtagccatt gcttcatctc tggcgttcca tcagggttgt tccaagcaat
     6481 gagggtatta tccaaatcga ccaaaacagc cttgattccc tgcgcctgca ggcttgggac
     6541 tgtcagatca tagactgctt ccacagcaaa atctggtata taattttcaa tcgccattct
     6601 ggctcctttt cttaactttt tttcgcaatt ttccttagta acaaggataa aacaatccac
     6661 aaacctgcac tagccaaact gatatagagc caagcatggg gcttatctgt taaaggtaag
     6721 ggaacattca ttccgaaaaa gcctgtcacg actgccaaaa cagctagcaa gactgaaatg
     6781 atagtcaagg ttgtcaaatt gtcattcaga ttattgttta gaatattgtt gtaagaggct
     6841 gaaagctgct gtaaaatctg agagattagg tctgtcatgg ataccagctg atgagcctca
     6901 atcatggcat catcaaactg ttctctctca atctcatcaa aactacgata caaggcatga
     6961 ccttgaatat gctctaacaa aatccgattt tgtttggcag ctgccgtcag ataaaccata
     7021 ccagtctcca aatcagacag ggcaaagagg tttttcttgg tagttcgctg gcgcaagagg
     7081 tcattgacct catccctact cttgtccatc tgctcaatga caggatagta ggcattgctg
     7141 atgatttcca gactggcaaa gagaaactta taaatcgaaa gcgtgtcatg gttctccaga
     7201 taacgagtca tctgttcaat gacataggcg ttcttggtat tactaatggt aatcaggcga
     7261 cgatgctcga caataaaggt catgggaaaa gtctcatagt aggccttgtc cttttttacg
     7321 tctaggacat tatagataaa ggtaaccgtc ccactttcac ggtggtagtc catgtgggcg
     7381 cgctcgtttc tatccagtgc gtattcaatg gtttccttgt ccaaaccgta aatttcagaa
     7441 aggtcttcta gtttattcaa ctttcctagg tctaggtcta tccaggtaca accattgccc
     7501 aactgctttt ctaaaaccat cttttctcct tattaaactc cctctattgt accacaaatt
     7561 acttaaaata acaggtctag tctgtgcgtg agaaattgct aacaactgtg atatttcggt
     7621 tagggacaaa gtgaagggct tgctcctcgc tacgaagctg tgtcgtacga attcccacac
     7681 tgacaacctt acccgataca gtaatcggtc catttgtcag aacgacctca tctcccacat
     7741 ccagttgacg ttcaaagagg atgaaaaagc cattgatgac atcagacaga aagccttggg
     7801 ctcccatacc aatcgctacc ccagcaatac cagctccagc cagcaaacta gaaactggca
     7861 aacctaaaat cgacaaaatg cagtagagta aaaagaaata tagcgtataa ttaaacacat
     7921 tttctagtaa acgtgagatg gttttttggc gtccgacatc atgacgagac atttttagag
     7981 aaggtttgac aattctctgc accatggtat gaagcatttt tttagcaata taaaatacaa
     8041 tcaaaagcag taaaagagaa atgaccttgg ttagaatatt ctcgataatg gttgtcacat
     8101 ctagcttttc aatataagcc tgaataaatt tttgcatata aaactccttt atttcattat
     8161 accatatttt catcagtctc attctccata aatattcaaa aaatagacag aaaattcttg
     8221 attttgtcta tcatttatac tataatcata atcactacac aaaaaggaga ttattatgaa
     8281 aagaatcatt catgcttgga ataaggcaag ccttgtcaag cgtatcttga ttggtatgct
     8341 ttgtggggaa tcctaggact gacccttcct aatctctcag ggattgggct actcggggat
     8401 ttattcgttg gaggtctgaa agctgttgct cctatcctag tctttgccct cgttgccaat
     8461 gccctttccc aacatcaaaa gggacaagat agcaatatga aaactgttgt tttcttgtat
     8521 atcctatgat agggactttc gccgctgctc ttgtagctgt actagcaagt ttcatcgtcc
     8581 ctattgaaat taccctaaat agtgccaata ctgaaattgc accaccagat gggattgggc
     8641 aggtcctcag caacctcttg ctcaaactgg ttgacagccc agtcaacgcc ctgcttactg
     8701 ctaactatat tggaatctta tcttgggcag tcatttttgg aatcgctatg agagaagcta
     8761 gtaaaaatag taaagaattg ctaaaaacta tcgctgacgt gacttctaaa attgtcgaat
     8821 ggatcatcaa tctggctcca tttggaatcc ttggtcttgt ttttaaagcc atttctgaca
     8881 agggagtcgg aagccttgcc aactacggta ttttattggt tccattagta acgactatgc
     8941 tttttgttgc ccctgtggtc aaccctttga ttgccttctt ctttatgaga cgcaatcctt
     9001 actctctagt ttggaactgc ctccgtgtca gcggtgtgac agcctttttc actcgtagtt
     9061 ctgcgactaa cattcctgtc aacatgaaac tctgccatga ccttggactc aacccagata
     9121 cctattctgt ttctatccca ctcggttcta ctatcaatat ggctggagta gcgattacca
     9181 ttaacctttt gacccttgct gcagttaaca ctcttggaat tcctgttgac tttgccacag
     9241 cctttgtcct cagtgtggta gcagctatct catcctgtga tgcttcaggt attgccggag
     9301 gttccctcct tcttatccca gttgcttgta gccttttcgg tatttctaac gatattgcca
     9361 tacaaattgt tggggttggt tttgtgattg gtgtcatcca agactcatgt gaaacagccc
     9421 ttaactcttc tacagatgtc ctctttaccg ccgttgccga atacgcagca acccgtaaaa
     9481 aataactcat caaggcaagc ctgctcatgt cttgtctttt acgcttttat tctaacttat
     9541 taggaaattc ttatgtctat tagccaacgt acgaccaagc tcatcttagc tacctgtctt
     9601 gcctgcctgc ttgcttattt tctcaatctt tcgtcagcag tttcggctgg aattatcgct
     9661 ctcttgagcc tatctgatac gcgtagaagt actttaaaac tggctcgcaa tcgtcttttt
     9721 tctatgcttc tagctctggc tatcggtgtt ctagcttttc acttgagcgg atttcatatc
     9781 tggagtctcg gcctctatct ggccttctac gttcctttag cctacaagat gggctgggaa
     9841 attggcatca caccaagcac tgttttggtt agccatctct tggttcaaga gtcaacctct
     9901 ccagaccttc tagtcaatga attccttctc tttgctattg gtacaggatt tgccttgctt
     9961 gttaatctct atatgccttc acgagaagag gaaatccagc actaccacac gctggtggaa
    10021 gaaaagttaa aagatatcct ccagcgcttc aaatactatt tatccagagg agacggacgc
    10081 aaccgagcac agctggtagc agaattagac acgcttttga aagaagccct cagactggtc
    10141 tatttggatc actctgacca cctctttcac cagaccgact accatatcca ctactttgag
    10201 atgagacagc gacaaagtcg tatcctgaga aacatggccc aacagattaa cacttgtcac
    10261 cttgccgcca gtgaaagcct gatcttagcg caactctttt caaaaattgc aggtcaactg
    10321 agccagacca atcctgcttc tgatttgcta gatgaaattg aacgttatct ggaagtcttc
    10381 cggaaccgca gtctgcccaa gacaagagaa gaatttgaaa cccgcgccac ccttcttcaa
    10441 ctcctacgtg aagccaaaac cttcatccaa gtaaaagttg atttttacca aaaatataga
    10501 cagtaaaaaa taaaaccact aaaaaacaga gcttgccagc attcttgaaa agtagtataa
    10561 ttattgcatg cgcaatcatc ttgtgacgca gagactgccc gttaatggac tttcttctat
    10621 ttatgactct aaaaagaaag gagacactat gacctatttg gaaaaatggt ttgacttcaa
    10681 tcggcgtcag aaagaaattg aaagtctctt ggaagagacc gttgcccaac agagcgagca
    10741 aagtctgacc ttgaaagagt tctacctgct ctactatctg gacttggctg aagaaaaatc
    10801 tctacgccag attgacctgc cagataagct tcatctgagc ccgagcgcag tttctaggat
    10861 ggtggctcgc ttggaagcta aaaattgcgg tctactcagt cgcatgtgtt gccatcaaga
    10921 tagacgctct agttttatct gcctgacaaa tgatgggcaa aagatactgg cctcgctaca
    10981 aaagactgtc gaagaaagct tggaagcagg tttggatttc ttgatttaag atgattttag
    11041 aaaaagttgc gtgcgcaatc atttttcttg acattctctt ttataaggag taaaataaag
    11101 ttagcattaa acaaaggagt tttaaatatg attgaaatta cctatataga tgccagcaag
    11161 aacgaaagaa ctgtgacttt cgagtcttat gaagactttg aacgttcgca acaagcttgc
    11221 cttatcggcg tcgcagacta ctaccctgtc caaaaattaa cttacaaggg tcataatttg
    11281 gactaccatg ggacttatgg agatatcttc ttctatctca tgaaacaaga tttaagccaa
    11341 tataactaaa aaaaggagaa atacaatggc aaaagcaatt acagatgcaa cattcgaaca
    11401 agaaacaaaa gacggtttgg tcttagtaga cttctgggca acttggtgtg gtccatgtcg
    11461 tatgcaaggt ccaatcttgg acaaattgtc tgaagaactt tcagaagatg tcttgaaaat
    11521 cgttaaaatg gacgttgatg aaaatccaaa cacagctcgt gcttttggaa tcatgtctat
    11581 tccaactctt ctcttcaaaa aagacggcca agttgtcaaa caagttgcag gtgttcacac
    11641 agcagaacaa atcaaggcca tcattgctga attgagctaa tcaaacgaga gaccaagtac
    11701 tttctttggt ctcttttttc ttgccctttg ccatttttca aaaaatatgc tagactatag
    11761 tagattgaaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa tcgatttaac
    11821 tgtcctgatc gatttgtcct gttcttattt cattttacta tataagtaga atattacgat
    11881 gtttgggata tgccatcgct aaaaaaactc gatttggtat tttttagctc cctaatagga
    11941 gctttttgca tgctctgaac atttcccatt ttggaaggag tactatgaaa cgtcaatcag
    12001 ccttggtcgt ctttagtggt ggtcaagatt caacaacctg ccttttctgg gttatgcaac
    12061 actatgaaac agtcgaagct gtcacctttg cctacggcca acgtcatcac ctcgaaattc
    12121 aaattgctag agaaatcgct aaggaacagg gcattcgtca ccatatcctc gatatgtctc
    12181 tgctgggaca aatcactgct cagccagact ttgcgacgat tcatatttcc tacattcctg
    12241 acaagctctg tgtcgagtca aaatccctca aactatatct atttagctac cgaaatcacg
    12301 gagatttcca cgaaaactgt atcaacacca tcgggaaaga cttggtcaac ttgctagacc
    12361 ctcgctattt agaagtctgg ggaaaattca ctccgcgcgg tggcatttca atcgacccct
    12421 actacaacta cggtaagcaa ggaactaagt atgaggactt ggcagaacaa cgcctcttcc
    12481 aacacgacct ttatccagag aaaattgaca accgctaaag tcatactcaa tgaaaatcaa
    12541 agagcaaact aggaagttag ccgcaggttg ctcaaagcag tgtttgaggt tgtagataaa
    12601 actgacgaag tcagctcaaa acactgtttt gaggttgcag atagaactga c
//
LOCUS       DBERCW010000049        12291 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.049, whole genome shotgun sequence.
ACCESSION   DBERCW010000049 DBERCW010000000
VERSION     DBERCW010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.049"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="ACL72M_001853"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="ACL72M_001853"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS0716931.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1693)
                     /locus_tag="ACL72M_001854"
     CDS             complement(1169..1693)
                     /locus_tag="ACL72M_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGS0716932.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1746..1982)
                     /gene="rpsT"
                     /locus_tag="ACL72M_001855"
     CDS             complement(1746..1982)
                     /gene="rpsT"
                     /locus_tag="ACL72M_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGS0716933.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(2050..2970)
                     /gene="coaA"
                     /locus_tag="ACL72M_001856"
     CDS             complement(2050..2970)
                     /gene="coaA"
                     /locus_tag="ACL72M_001856"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGS0716934.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3161..3564
                     /locus_tag="ACL72M_001857"
                     /pseudo
     CDS             3161..3564
                     /locus_tag="ACL72M_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3771..4361
                     /locus_tag="ACL72M_001858"
     CDS             3771..4361
                     /locus_tag="ACL72M_001858"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0716935.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4358..5635
                     /locus_tag="ACL72M_001859"
     CDS             4358..5635
                     /locus_tag="ACL72M_001859"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGS0716936.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5653..6315
                     /gene="deoC"
                     /locus_tag="ACL72M_001860"
     CDS             5653..6315
                     /gene="deoC"
                     /locus_tag="ACL72M_001860"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGS0716937.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6302..6691
                     /locus_tag="ACL72M_001861"
     CDS             6302..6691
                     /locus_tag="ACL72M_001861"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS0716938.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6782..7834
                     /locus_tag="ACL72M_001862"
     CDS             6782..7834
                     /locus_tag="ACL72M_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGS0716939.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7978..9513
                     /locus_tag="ACL72M_001863"
     CDS             7978..9513
                     /locus_tag="ACL72M_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716940.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGAINADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9506..10564
                     /locus_tag="ACL72M_001864"
     CDS             9506..10564
                     /locus_tag="ACL72M_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716941.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10567..11523
                     /locus_tag="ACL72M_001865"
     CDS             10567..11523
                     /locus_tag="ACL72M_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716942.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            11608..12291
                     /locus_tag="ACL72M_001866"
                     /pseudo
     CDS             11608..12291
                     /locus_tag="ACL72M_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3583 a         2180 c         2791 g         3737 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttgatgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgccc atcccaaaga atccatctga
     1321 taaactccca ctcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aaggctctaa agagacaggt caatggcaaa aaattgagaa
     1441 agatgatttg gtcagcttct tgcattcgtt cttggtagta gcaccaagaa taattaccat
     1501 cgatgaccca agctttatgc ttggtgagaa agttttttat ctcggttaac atccattcgc
     1561 agtcactgtc ttgccaacca ggttgaaatt ggagtgtgtc catgtgcagt tttggaatgg
     1621 agtagtagtt agataacttt tctgctagag ttgacttacc agaaccagaa tatccgataa
     1681 ttgtgatttt cattttctac cttttcctat ttggagacaa aaaaacagcc tctatggact
     1741 gtttcttatt tagcaagttt agttgaaaga cgagctttat cgcggcttgc tttgtttttg
     1801 tgaatcaaac ctttagtttc tgctttatcg atagctgagc tagcagcacg gaaaagttct
     1861 tcagatgggt ttgcttcgaa agcttttata gcagtacgca tagctgattt ttgagctgag
     1921 ttcttttcgt tttgtttaac gttcaattca gcgcgtttga tagctgattt aatgtttgcc
     1981 aatgttctta cctccatatt tactaactat accattatat atgaaaactt acgttttgac
     2041 aagggaaaat tactttttta agtaaatttc atcgatttca tggttcttgc ttttatgaag
     2101 aatcacttct gcacgatttc tggttggttc aatataattt tgcagatttg tgagattgat
     2161 actgatccag acctgatggg caaaggactc cacttcccca atcggcatct gagtaaaacg
     2221 ataatagtag ctatcagggt cgttttgggc taggctcagc atcttcaaga aacggtccag
     2281 ataccaactt tcaatatcat ctactccagc atctacatag atggaaaagt caaagaagtc
     2341 agtgatatag agacgatcgt tttgtggatt ttgaaagaca ttaattccct caacaattac
     2401 aaaatcagca gctttgacac tttgtttctt ttcgggtacg atgtcgtaaa cttcatgaga
     2461 atagacagga atatctacat cttgtccatt tttgatgcgg tccaagaagt tgagaagagc
     2521 ttccatatca tagctttcag gaaatccttt acgatttaaa atcccctgct caatcaaggt
     2581 ttgattggga tagagaaaac catcagttgt aaccaactca accgtagcat ctgtaaacgt
     2641 acgggacagt aggatttgaa gtaggcgact ggttgtggat tttccaacgg caacactccc
     2701 agaaacccca ataataaaag gttgagattt actttcacgt tggaggaaaa ttccttttga
     2761 aaaggctaaa tcttccttag ttcgcttgta aatctgaatc agatgagcca aggggagata
     2821 gatatctgta acgtcttgga gactgatttg gtcattaaaa ctcttgatag attccaattc
     2881 ttcttctgtc aaaggaggtg ttgtctttcg atgtaaagat tgccaagtct ggcggctgat
     2941 tttttcaaaa tgtaaaaatt cgttggtcat ttgttttccc ctagatattt tgtctatcat
     3001 accataaaaa gctaaaaaaa taaagcggtt tcttgaatgt ggtaagtcaa tggtatatag
     3061 tataagtgat caatttattg atgaaatagg agatagattc tactgattta taagcttata
     3121 aagggggctt tttagttcac aacttagtag gaggtgtact atgaaaatct taaaacgtta
     3181 tatattggaa ctctgtttta ttttaagttt tgctttacct tttataaaag gaaccaatgc
     3241 agataatggt agatgctttg tggaaaccta ttacggtttt acttttttga tggaacatgc
     3301 tattgtaaca gctgtcttta tctgttcgtt cttaattgct ttcttactaa aaaacgatgg
     3361 acgaaatgga ttgctgcggg tagttattgc tttttagtcc tacggattgc gacagagggt
     3421 tatttcttcc acatgtcact agaagatttg atacgacttt ggacaagttt ggaaatcctg
     3481 acacaaacgt atcagttggg cttttatcta aacattttgt taggaatttt gttgataata
     3541 aagtatttta aggttaagca atagaaataa taatctgcct gattatagat gataaacttt
     3601 ttgtttttat ctggactgtg atatttatag ttctaaatgg tttattattt ataagtgttg
     3661 aaagagattg aagaaaatgg cttcgtgact tgctttcttc ggtctttttc gttttattat
     3721 caatttgtaa acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa
     3781 tgtactatgc agaaaatcct gacgctgctc acgacattca tgagttgaga gtggacttgt
     3841 tgggagaaaa aatgactttt ttgacagatg cgggtgtttt tagcaagaaa atggttgact
     3901 ttggaagtca actcttgctc aagtgtctgg atgtcaacca aggagagaca gtcctagatg
     3961 taggctgtgg ttatggtcca ttaggtttgt ccttggtcaa ggtttacgga gttcaggcga
     4021 ccatggttga tattaacact cgtgccctgg atttagctca gagaaatgct gaaaaaaata
     4081 atgcaaaagc gacgatattt caatctaata tttatgcaag agttcaaggg cgatttgacc
     4141 atgtcatttc caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcatcgaga
     4201 aaagtaaaga tttcttggaa attggtggag atttgaccat cgtcatccag aaaaaacaag
     4261 gagctccaag tgccaaatct aagatggaag atgtgtttgg caattgtgaa atccttaaaa
     4321 aagacaaggg atactatatc cttagaagtg tgaaagaatg agagcagttg atttaatcca
     4381 aaaaaaacga gacggtcaag aactgacttc aagtgaaatt gaatggctga tagaaggcta
     4441 tgtatcagga actgttcctg attatcagat gtctgccttt gctatggctg tttattttaa
     4501 aggaatgacg actcgagaaa tctctgattt aacgatgaat atggttaaga ctgggcaaga
     4561 gtttgacctg tcagccattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg
     4621 cgataaggta accttgattt tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa
     4681 aatgagtggt cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattag
     4741 gggctatcaa gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt
     4801 atctgtcatt gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg
     4861 tgatgtgacc gcaactgtcg acacgattcc tttgattgcg agttcggtga tgagcaagaa
     4921 aattgcggca ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat
     4981 gaagacggtt gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt
     5041 tggacggaag acagtagcag tgattacgga tatgagccag cctttggggc gagcgattgg
     5101 aaatcgtctg gaaatccttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat
     5161 tacccacttt atttgtgaat tggctcaaat tatgcttggt ttggcaaatg ttaacaaaac
     5221 tgttgaagaa gttcgccaac atcttgaaaa tggtcaagca ctggctaagt ttgaggaaat
     5281 ggtgcaagcc caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt
     5341 ggtggaaatc cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg
     5401 tctttatgcc atgaggctgg gtgctggtcg tgcagttaag tctgatgtct tggactatga
     5461 aacaggaatt gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc
     5521 aaaagtatac acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt
     5581 taaaataagt gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga
     5641 gggaaaaccg aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca
     5701 aagaaaaaac aaattgatag tttgttgtct gaggctagag agtatggctt tgccagtgtt
     5761 tgcgttaatc cgacctgggt tgaacatgct aaaaaaggac ttgaaggcac agatgttaag
     5821 gtttgcacag tagtaggttt ccccttggga gcaacaactt caactgtgaa agcttttgaa
     5881 acaaaagaag ctatccaaaa tggggctgat gagattgaca tggtaatcaa tgttggggct
     5941 ctcaagtcag gtgatttggc cttggttgag tcggatattc gtgcagtagt ggaagcaagt
     6001 ggggacaagt tagtgaaagt tattattgaa gcttgccttc tgacagacca agaaaaagtt
     6061 ttggcttgcc aattagccca aaaagcagga gctgactttg tcaaaacatc tactggcttt
     6121 tcaactggtg gtgctacgat agcagatgtt agattaatgc gtgaaacagt tggacctgat
     6181 atgggtgtca aggccgccgg tggagctcgt tcttatgcag atgctcttac ctttgtcgaa
     6241 gcaggtgcga cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca
     6301 gatggcgact actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc
     6361 ctattctcac tttcctatcg gagcagtttt agtagccaaa gacggaagtg tttacacggg
     6421 agtgaatatc gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagctatttt
     6481 taaggctata tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga
     6541 aaaaccgatt tcaccatgtg gtgcttgtcg ccaagtaatg gtcgaatttt ttgaacaaga
     6601 tttaaaagtg accctagtcg caaaagataa atcgacggtc gagatgacgg tcggggagtt
     6661 acttccatac tcttttacag acttaaatta gtctgagtcg ctctttgagt ggcaagggtc
     6721 tttgtgacca atcaatccat acttgcaaca tcgttgcaca tcttatttag gaggttcagt
     6781 aatgaacaag aaacaatggc taggtcttgg cctagttgca gtggcagcag ttggacttgc
     6841 tgcatgtggt aaccgctctt ctcgtaacgc agcttcatct tctgatgtga agacaaaagc
     6901 agcaatcgtc actgatactg gtggtgttga tgacaaatca ttcaaccaat cagcttggga
     6961 aggtttgcaa gactggggta aagaacacaa tctttcaaaa gataacggtt tcacttactt
     7021 ccaatcaaca agtgaagctg actacgctaa caacttgcaa caagcggctg gaagttacaa
     7081 cctaatcttt ggtgttggtt ttgcccttca caatgcagtt gaagaagcag ctaaagaaca
     7141 cactgacttg aactatgtct tgattgatga tgtgattaaa gaccaaaaaa atgttgcgag
     7201 cgtaactttc gctgataatg agtcaggtta ccttgcaggt gtggctgcag caaaaacaac
     7261 taagacaaaa caagttggtt ttgtaggtgg tatcgaatct gaagttatct ctcgttttga
     7321 ggcaggattc aaggctggtg ttgcgtcagt agacccatct atcaaagtac aagttgacta
     7381 cgctggttca tttggtgatg cggctaaagg taaaacaatt gcagccgcac aatacgcagc
     7441 cggtgcagat attgtttacc aagtagctgg tggtacaggt gcaggtgtct ttgcagaggc
     7501 aaaatctctc aacgaaagcc gtcctgaaaa tgaaaaagtt tgggttatcg gtgttgaccg
     7561 tgaccaagaa gcagaaggta aatacacttc taaagatggc aaagaatcaa actttgttct
     7621 tgtatctact ttgaaacaag ttggtacaac tgtaaaagat atttctaaca aggcagaaaa
     7681 aggagaattc cctggcggtc aagtgatcgt ttactcattg aaggataaag gggttgactt
     7741 ggcagtaaca aacctttcag aagaaggtaa aaaagctgtc gaagatgcaa aagctaaaat
     7801 ccttgatgga agcgtaaaag ttcctgaaaa ataatggatg gaagtcattt cttaggaagc
     7861 ggccaagggc cgctttttta agagttgaga caaagtcatt ttgtctcagt aaagcttgct
     7921 actagacaaa ctagcaagtt ttattgaaat aaaataagac tctgaaagga agagcacatg
     7981 gcacacgaaa atgtcattga gatgcgtgat attaccaagg tgtttggtgg atttgttgcc
     8041 aacgacaaaa tcaacttgca cctacgaaaa ggtgaaattc atgcactttt aggagaaaat
     8101 ggggctggta agtccacgct aatgaacatg ttagcaggcc ttcttgaacc aaccagtggt
     8161 gaaatcgcgg tcaacggtca agttgtcaat ctcgactccc catctaaagc agctagcttg
     8221 ggaatcggga tggttcacca gcactttatg ttggttgaag ccttcacagt ggctgaaaac
     8281 atcattttag gtagtgaatt gactaaaaat ggtgtgctag atatcgctgg agctagcaaa
     8341 gaaatcaagg ctctttctga acgttatggc ttagctgttg acccttctgc caaggtagca
     8401 gatatctcag ttggagccca acaacgtgta gaaattttaa aaacacttta tcggggggct
     8461 gatatcctta tctttgacga accaacggct gttttgactc catcagaaat tgatgagttg
     8521 atggctatta tgaaaaatct tgtcaaagaa ggaaaatcaa ttatcttgat tacccacaaa
     8581 ttggatgaaa ttcgcgcagt ttctgaccgt gttacagtta tccgtcgtgg gaaatcaatt
     8641 gaaaccgttg aaattgcagg ggctatcaat gctgatttgg cggaaatgat ggtaggacgt
     8701 tctgtttcct ttaaaacaga gaagcaagcc tctaaaccaa aagaagtggt tttgtctatc
     8761 aaagatttgg tggtcaatga aaaccgtggt gttccagctg ttaaaaatct gtccttggat
     8821 gttcgtgctg gagagattgt tggtattgcg gggattgatg gaaatggtca gtctgaactg
     8881 attcaagcca ttacaggtct tcgtaaggtt gaatctggta gcattgagct aaaaggagat
     8941 tcaattgtag gcttgcaccc acgtcagatt acagaactaa gtgttgggca cgttccagaa
     9001 gaccgtcacc gtgatggctt gattttggaa atgatgatat ctgaaaatat tgcccttcaa
     9061 acctactata aagaaccaca tagtaaaaat ggaattttga attattcaaa tattacttct
     9121 tatgctaaaa agctgatgga agagtttgat gttcgcgctg ccagtgaatt agttcctgca
     9181 gctgcactct caggaggaaa tcaacaaaaa gcaattattg ctcgtgaaat tgatcgagat
     9241 cctgatctcc ttatcgttag ccagccaact cgtgggttgg atgtcggtgc cattgagtat
     9301 atccacaaac gcttgattga agagcgtgat aatggcaagg ctgtccttgt tgtcagcttt
     9361 gaattggatg agattttaaa cgtctcagac cgtattgccg ttatccacga tggtaagatt
     9421 caaggtattg tatcaccaga aacaaccaat aaacaaggac ttggtgtctt gatggctggt
     9481 ggaaacttgg gaaaggagaa gagtgatgtc taaaaaatta caacaaattt cggttccctt
     9541 gatttctgta ttcctaggaa ttttactcgg agccattgtc atgtggatct tcggttatga
     9601 tgctatttgg ggctacgaag aattgttcta tacagccttt ggcagtctgc gtgggattgg
     9661 agaaatcttc cgtgctatgg gtcctctggt cttgattggt cttggttttg cggttgccag
     9721 tcgagctggt ttctttaacg tcggacttcc tggtcaggct ttggcaggtt ggattctcag
     9781 tggttggttt gccctgtcgc atccagatat gccccgtccc ttgatgattc tagcaaccat
     9841 cgtgattgcc ttgattgctg gtgggattgt cggagcgatt ccaggtattc ttagggccta
     9901 tctagggacg tcagaggtta ttgtaaccat catgatgaac tacattgtct tgtatgtagg
     9961 gaatgccttt atccatgctt tccctaaaga cttcatgcaa agtacagatt cgaccattcg
    10021 tgttggggct aatgcaacct atcagacacc ttggttagct gagttgactg gtaactcacg
    10081 gatgaatatt ggtattttct ttgccatcat tgccgttgca gttatttggt tcatgctcaa
    10141 gaaaacaact cttggttttg aaatccgtgc agttggtctt aatccacatg cttcagaata
    10201 tgctggtatt tctgccaagc ggactattat cctatctatg attatttcag gtgccttggc
    10261 aggtcttggt ggagctgttg aaggtttggg aaccttccag aacgtctatg ttcaaggttc
    10321 gtcattagct atcggattta acggaatggc ggttagtttg cttgcggcca actcaccaat
    10381 tggtatactc tttgcagcct tcctatttgg cgttctccaa gttggggctc ctggtatgaa
    10441 tgcggcgcag gtaccatctg agctcgtcag cattgtaaca gcgtctatta tcttctttgt
    10501 cagtgttcat taccttatcg aacgctttgt caaaccgaaa aaacaagtta aaggaggtaa
    10561 gtaaagatgt ctattataac cttgctcccc ctcttggtgt cttctatgct gatttactca
    10621 gcacctctca tctttacaag tatcggtggt gttttctctg aacgtggtgg tgtggtaaac
    10681 gttggccttg aaggaattat ggttatgggt gccttttctg gagttgtctt taaccttgaa
    10741 tttgcagaac aatttggagc agcaactcca tggctatcct tgcttgtagc aggattggtt
    10801 ggtagtgttt tctctatcat ccacgcagca gcgacggttc atttccgtgc agaccatgtt
    10861 gtcagcggta cggtattgaa cttgatggcg cctgccttgg ctgttttctt agttaaagtt
    10921 ctttataaca aaggacaaac cgacaaccta agtcaaactt ttggacgctt tgatttccca
    10981 gtcttggcaa atatcccagt gattggtgat atcttcttca agtcaactag tctacttggt
    11041 tatctggcga ttgccttctc attccttgct tggtttattc tctttaagac tcaatttggt
    11101 cttcgtctcc gctctgtcgg tgaacatcct caagcagcgg ataccttggg aatcaacgtc
    11161 tacaagatga gatatttagg ggttattatt tcaggttttc taggtggaat tggcggagcg
    11221 atttatgcgc aatcaatctc agttaacttc tcagtgacaa ctattgttgg acctggattt
    11281 atcgcccttg ctgcgatgat ctttgggaaa tggaatccaa tcggtgctat gctttctagt
    11341 ctcttctttg gactttcaca aagtttggct gttatcggtt ctcaattgcc gttcctacaa
    11401 ggagtgccag cggtttatct tcaaattgca ccttatgttt tgacaattct tgtcttagca
    11461 gccttctttg gaaaagcagt cgcaccaaaa gcagatggta tcaactacat caaatcaaaa
    11521 taagcataca aaaaaacgtc agtccaatga ctgaactgcc ccccaaaagt tagacagaaa
    11581 aaatctaact tttggggtgt ttttattatg aaattaactt atgatgataa agttcagatc
    11641 tatgaactta gaaaacaagg atatagctta gagaagcttt caaataaatt tgggataagc
    11701 aattctaata ttaggtacat gattaaattg attgatcgtt acggaataga gttcgtcaaa
    11761 aaaggaaaaa atcgttacta ttctcctgat ttaaaacaag aaatgattaa taaagtctga
    11821 catgaaggct ggactaaaga cagagtttct cttgaatacg gtctcccaag tcgtacgata
    11881 cttcttaact ggctagcaca atacagaaaa aaacgggtat actattgttg agaaaacaag
    11941 agggagagta cctaaaatgg gacgtaagcc aaaaaagaga cctgaagaga ggacagaatt
    12001 agaacatctt caagcagaaa atgagtacct gagagcggag aatgccatcc taaaaaagtt
    12061 aagagaactc cgattgaagg aggaaaaaga gaaagaagaa agacagaaat tgttcaagaa
    12121 ttaatgactg agttttcgtt agatattctt ctaaaagcca ttaaactagc tcgttcgacc
    12181 tactactatc acttgaaaca gctagacaaa ccagataagg accaagagct taaagctgaa
    12241 attcaatcca tttttatcga acacaaggga aattatgctt atcgtcggat t
//
LOCUS       DBERCW010000050        12026 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.050, whole genome shotgun sequence.
ACCESSION   DBERCW010000050 DBERCW010000000
VERSION     DBERCW010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.050"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(169..1371)
                     /gene="rpsA"
                     /locus_tag="ACL72M_001867"
     CDS             complement(169..1371)
                     /gene="rpsA"
                     /locus_tag="ACL72M_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGS0716943.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1533..1604)
                     /locus_tag="ACL72M_001868"
     tRNA            complement(1533..1604)
                     /locus_tag="ACL72M_001868"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1570..1572),aa:Gln,seq:ttg)
     gene            complement(1614..1694)
                     /locus_tag="ACL72M_001869"
     tRNA            complement(1614..1694)
                     /locus_tag="ACL72M_001869"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1658..1660),aa:Tyr,seq:gta)
     gene            complement(1744..1974)
                     /locus_tag="ACL72M_001870"
     CDS             complement(1744..1974)
                     /locus_tag="ACL72M_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGS0716944.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2142..2786)
                     /gene="pcp"
                     /locus_tag="ACL72M_001871"
     CDS             complement(2142..2786)
                     /gene="pcp"
                     /locus_tag="ACL72M_001871"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGS0716945.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2801..3724)
                     /locus_tag="ACL72M_001872"
     CDS             complement(2801..3724)
                     /locus_tag="ACL72M_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGS0716946.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3721..4410)
                     /locus_tag="ACL72M_001873"
     CDS             complement(3721..4410)
                     /locus_tag="ACL72M_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGS0716947.1"
                     /translation="MEWIRLIGIAIIVVGFIFKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4475..5179)
                     /locus_tag="ACL72M_001874"
     CDS             complement(4475..5179)
                     /locus_tag="ACL72M_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0716948.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(5235..6257)
                     /locus_tag="ACL72M_001875"
     CDS             complement(5235..6257)
                     /locus_tag="ACL72M_001875"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGS0716949.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6389..8860)
                     /gene="parC"
                     /locus_tag="ACL72M_001876"
     CDS             complement(6389..8860)
                     /gene="parC"
                     /locus_tag="ACL72M_001876"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGS0716950.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9061..9265)
                     /locus_tag="ACL72M_001877"
                     /pseudo
     CDS             complement(9061..9265)
                     /locus_tag="ACL72M_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(9280..11223)
                     /gene="parE"
                     /locus_tag="ACL72M_001878"
     CDS             complement(9280..11223)
                     /gene="parE"
                     /locus_tag="ACL72M_001878"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGS0716951.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGFKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAVVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11359..12000
                     /gene="plsY"
                     /locus_tag="ACL72M_001879"
     CDS             11359..12000
                     /gene="plsY"
                     /locus_tag="ACL72M_001879"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGS0716952.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3475 a         2736 c         2107 g         3708 t
ORIGIN      
        1 aactttgaaa acttcaaaaa acggattttt atcgctctga acatcaaaaa agaaaggacg
       61 aaatttgtcc tttctcaacc ttagctgact tcaacccact acagttgaca aagagccaga
      121 aaaatccctt gtttagtaaa caaaggattt tgtgaatttt caatttgatt aaagttcgat
      181 atcaccaaac aaatcagcca ttgaaaatcc tgtttgtgtt tctggaagtt cgaaatcacg
      241 cttttcttga cgtcttggac gacgtggacg agcagcacgt ttttcttctt tttgtccttc
      301 ttcttgggct ggacgttctt caagagcttt aatagaaagt gatacgcgtt ctgcatctgc
      361 gttaacttca agaactttaa cttgaacttc ttgaccaact ttaagagctt cttttggatt
      421 ttcaatccgt ttgtgtgaaa tttgtgatac gtgaacaagt ccatcgatac ctggcaatac
      481 ttcaacaaat gcaccgaagt cagtcaaacg tttaactgtt ccttctacta catcaccttt
      541 agccaatttt tgctcaacgc catcccatgg tcctggtact gttgctttaa gtgaaagtga
      601 tacacgtcct tcttcttcgt taagatcaag gattttcact tcaatttctt caccaacagt
      661 tacaactgat tttggtgata cgttacgttc atgtgacaat tcagtcaagt gaaccaatcc
      721 gtcaacacca ccaaggtcga tgaaagcgcc gaagcttgtg atacgagcaa ctttaccagt
      781 tacaacatca ccaacagcca atttaccgaa tacttcagcg cgagctgctg cagtagctgc
      841 ttcaacaact tcacgacgtg aaaggatgaa gcggttttct ttagcgttaa cttctttgat
      901 tttagtatca aattcttgac ctacaaaacg ctcagcgtta cgtacgaaac gagtatccaa
      961 cattgaagct gggataaatc cacgaacacc ttcaaattct actgaaagtc cacctttaac
     1021 ggcacgcgtt cctttaacag taacaacttc ttcttcgcga ccaacaagtt tgtcccatgc
     1081 tttgcgagct tcaaggcgtt ttttagatac aaggtatgta actgtatcag tatctttacc
     1141 aactacttga cgaagtacaa gaacatccaa tacttctcct actttaacaa agtcattgat
     1201 atctgcatca cgatcgtttg tcaattcgcg aagagtcaag acaccttcaa caccagttcc
     1261 agagattgca acgttagctt gagtcgcatc aactgtcaat acttcagcac taacaacatc
     1321 accagtctca acttgactaa cgctatttag caaatcttca aattcgttca tctaaaaaat
     1381 cctccaacaa tcaagttttt cttaaacttg acatacttat aatttttttc ctaagcaccc
     1441 gcaaggacat gttcatatca ttcacgtctt tcaattataa aaataaaata ccctaagata
     1501 ttttgctttt tatcttgatt attacctaag aactggggta gctggattcg aaccaacgca
     1561 tgagggagtc aaagtccctt gccttaccgc ttggctatac cccattaatg aaatggagag
     1621 agagggattc gaacccccga acccgaagga gcggatttac agtccgccgc gtttagcctc
     1681 ttcgctatct ctcctacaat caacatggac tattatatca tgaaaatttc aaaaaaacaa
     1741 gacttatttt gctaaattat aattttcaat caaaatttcc acagcttttt ccaatttttt
     1801 ataaaaacta tcgacattcc cattctttat aatggcaaat tgtccgtcta attcggcaat
     1861 ttctccgata acttttttac cgatagtcaa tgtataacct tcaaaactgt ctttaccaac
     1921 attaactttg gcatccgcta cttgaatttc gattttttta tctttcttgc tcatttcata
     1981 cctctcttca ctttttctat tttacaagaa aatcctaaaa ctagcaagaa aaaactctat
     2041 atcaggcttc tctgatatag agttttatgt aaacaacctc aatcgattta gcatagctaa
     2101 tagttagtaa acaagcataa ttgactatcc tttttaggtt atcagtgagt ctcaccgcct
     2161 actaactgca aatccttatc tttgtagtct acaatagctt caatagctac ctctatgcct
     2221 cttacaatat cacatagact cattcctgca gtattcggct tatttactac ttgttccatc
     2281 atatatggaa tatgcatgaa acctgctctc atattaggga attttttatc cactaaataa
     2341 agagcttggt acatcaaatg attgcaaaca aaggttcctg cactattgga tacaactgcc
     2401 ggaagtccct gttttttgat agcttgtacc atcgctttga taggtaaact actaaaatag
     2461 gccgatgctc catcaatacg aatcggtgta tcaattggtt gattgccttc gttatcaggt
     2521 atgcgagcat catcttgatt aatagccact cgttcaggtg ttaagccggt cctgccgcct
     2581 gcttgtccaa tacaaagtac agcatctggt tgatatcgta atatttctgc ctctaaaact
     2641 tctgacgact tataaaaaac cgttggaatt tctacccagc gaacttcagc cccattaatc
     2701 tcagatggta ataattttac agcctccaaa gctggattaa tcttttcacc tccaaaagga
     2761 ttaaaacctg taaccaatat tttcatttta ttttccttta ctaaaatgcg agaaagtaca
     2821 ttaagaatat gtgaataaca atcattacta gagcaacacc tgcttgagcc tttataacgc
     2881 cattctgatc tttcatatcc atcaatgctg ctggtagagc gttaaaatta gcagccattg
     2941 gggtcaataa ggtcccacaa taacctgctg tcatggcaag agcaccagcc acaattggat
     3001 tagctcccag agcaaataca aagggaactc caacacctgc tgtaataacg gtgaatgctg
     3061 caaaagcatt tcccataatc attgtgaata gaaccattcc aagaacatag gccaaaactc
     3121 ctataaagcg actatctgaa ggaacaatac cgctaatcag atgagagata acatcaccaa
     3181 cacctgctac agtaaaaata gcccccaaag cccctaataa ttgaggaaca ataccacttg
     3241 ttgaaacttg ctgagtcatt cgattatttt ctgataacag actcttaggg tgactattgg
     3301 taatcacaag aacagaaatt gtagcaaaca aggcggcaag gctaatcgaa atcttgctaa
     3361 attctggaat catttgcgct aagaccaacg caagtattgc catcagcata actggaataa
     3421 aaattttatt tttcaacctg ttagattcaa tattggcttt catttcatct aaggatggca
     3481 aggttccgat acggacttgc ttaaacaatg ttaacagcga taataggatt acaataatac
     3541 caatactcat atttggcata taggaaccac ctataaacgt aatagacaat agagtccaaa
     3601 atgcagatgt cccaagtcga actgggtttg ttttatcttt ataactacaa taggctgtat
     3661 ggagaaattg acaaccaatc acaatatagg tcaactctaa tagttgcttt gccaactctg
     3721 tcatttttgt tctcctcccc tagtcttttt tgatatcaat tttttatcaa ataaataatt
     3781 gtaaatcccc actacaataa gtgttataac agcaacaata atagatgtag aagcaatccc
     3841 tgcataattg ctttcatagc ctaactgatc taatgttccc cctatcaaga ggactccccc
     3901 agcacctaca aacgtatttt gagcaaagaa atttccaaaa ttttcattcg cagccgcacg
     3961 cgcttttatt gtctcatctt caacctctgt taactttcta cctaattgag actctgcagc
     4021 tgcttctccc ataggttgaa ccaaaggtct gacaaactga gggtgtcctc ctagacgaat
     4081 tgaaaagaaa ccagctaact ctcgaataaa aaaataaact gtatagaagt ttccaactgt
     4141 cagaccttta atctttcgaa tcaaatcgat tgatcgttgc ttgagtccaa aggtttctga
     4201 cagccccaca agaggcaagg taaccataaa aatcgtgagc actcgctgat tgctaaattc
     4261 ttttcccaaa atctccaaaa attcaacgag agaaacacct gaaactaaag ctgtaaccaa
     4321 accagctaag actactgttg caattgtatc aaatttaaaa ataaaaccca caacaatgat
     4381 tgctattcct attaatctaa tccactccat atcaaactcc tttatattca aaatgacagt
     4441 attttaaaaa ttttatcaag atcaatacca ttccttattt aatgtatttt tctagttctt
     4501 tttggtattt gctattggat tccaattttt ctttttgcca ttttttaaaa acctcgttat
     4561 attcttttgt tgtaacaata tctttttgca atttcattcc tttaaagata tatggttccc
     4621 ccttaatacc aacttgtgag tatggttttg agaatggtac tacgttactt acaactggag
     4681 aaccaccaga tgaagctgtt ggcatcaata atgaactatc tgtcgaccaa gcttgagctt
     4741 tggcatattt ttcatatctc ttctctaggt cagtggtctc agaaacagca tcttctaaca
     4801 atttcttata tttatccaaa ccaggtttag ctacaacatc cttatctttt cctttcgtaa
     4861 taccaaggtg tttcatggca gaaccagatt ttggatccat aatattcaag taagacgctg
     4921 gatcttgata gcttggagcc catcctgtac tattcaaatc atagtctttt tgagaaggag
     4981 caacattgcc gtatttatca ttttccatca aaccatcaat aacatttcca ataacgtctg
     5041 tcctcgatgt tcgagtcgct atactgtagc ccaatgatgc tggatctact gcatagacat
     5101 aagaaaatgt tgtcggtgca tctgcttctt tatcagtttt tccacaagcc actaaaatag
     5161 ctgacgtgct caggaccact cctgctgtta agagccactt tttctatttc ataaaaaatc
     5221 tcctttggtt tattttaatc tacttttaca atccaacctt ctggcgcttc aatatcgcca
     5281 aactgaatac ccgtcaattc attatataat ttacgcgtca caggacctac ttctgtttca
     5341 ctatagaata catggaaatc atcaccatgt tgaatacctc caattggaga aataaccgct
     5401 gctgtaccac aggcacctgc ctctacaaaa cggtcaagat tatcaattgg aacatcaccc
     5461 tcaataggag ttaatcccaa gcgatgttct gccaaataaa gcaaggaata cttggtaata
     5521 gatggcaaga tagatggact caatggtgtt acaaattcat tatcagctgt aattccaaag
     5581 aagttagctg atccgacttc ttcaatcttt gtatgagttg atgggtccag atagataaca
     5641 tctgagaaat gacgtgactt ggccattttt cctggtaaga gacttgcagc atagtttcca
     5701 ccaaccttag ccgcacctgt accatttggt gctgcacggt cgtactcatc ctgaatcaag
     5761 aagttggttg ggaccaaacc acctttaaag taatttccaa ctggcatagc aaagatggtg
     5821 aaaatgtact cttctgccgg ttttaccccg ataatatctc cgacaccaat caaaagaggg
     5881 cgaagatata aggttccacc tgttccgtat ggtggtacgt attcttcatt cgcacggaca
     5941 actgctttac aagcttctac aaacatgtct gtcggaactt gtggcatcaa gagacggtca
     6001 catgtacgtt gcagacgttt agcattttca tcaggacgga acagttgaac actgccatcc
     6061 ttagtacgat aagctttcaa accttcaaat gcttgttgtc catagtgaag acttggagaa
     6121 gactctgaaa tatgcaaagt tgcatcctct gtaagctctc cttgatccca ttgtccattt
     6181 ttgaaatgag caagatagcg ataaggtaat ttcatatagg aaaaaccgag gttttcccaa
     6241 tcaatcgtta ctgtcatatt ccactcctta ttctaaaaac ctatttctta tattctacac
     6301 tatttttcta aaatagcaag tatattttgt aattttcaga aaatttctcc aataaaaacc
     6361 agctcttaga actgattctt catttcactt atttatcttc agtaactact tcctgaagat
     6421 aagcgtcaaa aacttcttca tctgaaatcg tgtcagaaat gaagcttcca ttgctagtgc
     6481 gttctgacaa gttcaagtct tgcaatcggc tttcatagat tgttccttta ttggattgga
     6541 caagcagagt ttggtcgttc acatccactt ccgtactgaa gaaatcgcca acaaatcctt
     6601 gctctgcaac tgctcctgcc aagaagacac gatgcggttt gtttttcaac tcacgcaaga
     6661 cttgtaatcc tcgtttggca cggctggttg ctagaatttc ctcaatggaa acacgtttca
     6721 agcttccacg ctgggtcaag aggtagaagg acgaagtatt acagataaag ccagattgga
     6781 ggacatcatc ttctttcaaa ttcatagcct tgacacctgc tgccttagca ccgacaaccg
     6841 gaacctcttc gatattgaaa cgcagggcat aaccattttg actaaccaag acaacatcat
     6901 ctagtttaat cggagccact gctacaatct gatctgtatc gtctttgagc ttagcatact
     6961 tgacagactt agatctatag gtccgccatg gagtgaattc ttttcgctct acccgtttga
     7021 tttgaccaag gcgagtcact gcaaagtagg ttgtcgcatc gtcaaactga tccagtactt
     7081 ccacataaag gatttcttca ttcgtttcaa agtttgtgat ggtttggctc agatgctctc
     7141 cgatgtcctt ccaacgaata tctgccaact catggattgg tctgtagatg acatttccaa
     7201 gacttgtgaa catcaagagg tgctgggttg tcttggcaga ttgaacaaaa atcaaacggt
     7261 catcatcacg cttgccaatt tcttccaagg tggaagccgc aaaggaacgt ggactggtac
     7321 gcttgatgta acctgccttg gtcacgctga cgtaggtatc ttcctcagcg ataagactag
     7381 ctgtatcaat ctcaattgct ttcgcagtgt cttctaaaga actcaaacga ggagttgcaa
     7441 atttcttctt gacctcacga agttctttct tcatgagatt gtacatagtc ctttcatcac
     7501 cgataatagc cgccagcata gcaatcttct cacgaagctc tgcttcttct tcctgcaaga
     7561 caaccacatc ggtattggtc aaacggtaca gttgcaaagt tacgatagcc tcagcctgtt
     7621 cttccgtaaa atcatagcta actttgaggt tttccttggc gtccgcctta ttctcagaag
     7681 cacggataag agcaatgact tcatccaaaa tcgaaatcac acgaatcaaa ccttcgacga
     7741 tatggagacg tttctcagcc ttttctttgt caaagcgtga acgcgccaaa atcacttctc
     7801 gacggtgagc gatgtagcta gacaggattg gaacaatccc aacctgacga ggtgtgaaat
     7861 tgtcaatcgc caccatatta aagttgtagt tgatttgtag gtcggtgtac ttaaataagt
     7921 agttgagaac aagctcagta ttagcgtctt tcttaagttc gatagcgata cgaagaccat
     7981 cacggtcaga ctcatcacga acctcagcaa tcccagctac cttgttatta acacgaacat
     8041 catcgatttt cttgactaga ttggccttat tgatttcata aggaatctca gtaataacga
     8101 tttgttcctt accacctttt agcttttcaa tttcagtctt ggaacgaaca accacgcgcc
     8161 ctttcccagt ttcataagct ttcttgattt catcacgacc ctgaataata gcccctgtag
     8221 ggaagtctgg tccaggcaag aattccatga gtttatcaat ctttgcagtt gggtggtcaa
     8281 tcatgtaaac tgcagcatct atgacctcag ctaaattatg gggaggaatg tctgtggcat
     8341 aaccagccga aatcccagtc gaaccattga ccaagaggtt tggaaaggct gctggcaaga
     8401 ccgttggttc tttctccgta tcgtcaaagt tccatgcaaa aggaactgta tttttctcga
     8461 tatcctgaag aaggtaacct gcaatttcag acaaacgtgc ctcagtataa cgcatagccg
     8521 caggaggatc tccgtccata gaaccgttat taccgtgcat ttcaactaga atctcacgat
     8581 ttttccagtt ctgtgacata cgaaccatgg catcatagat agaagaatcc ccgtgtgggt
     8641 ggaaattccc catgatgttc ccgactgact tggccgactt acggtagctc ttgtcaaaag
     8701 tattgctatc cttattcata gaataaagaa tacggcgctg aaccggcttc aacccatcac
     8761 gaatatctgg caaagcccgg tcttgaataa tgtacttgga gtagcgacca aagcgctctc
     8821 ccatgatgtc ctccagggac atgttttgaa tgttagacat aagatacaaa gcccataaaa
     8881 taccaagtga aaatagaaaa ttcttgaagt aagcaaactc acaagagaat ttatcttttt
     8941 cacacagtat ctagggcgtg ttcaactcct ttcaaagaat gtagagtagg tttttatgca
     9001 gtaaaagata ttttacggga attcctcccg tgttcagtta cgataagtaa ccaaactatc
     9061 ctgtttgtat ttttcaatat gaaaatctgg ttttccaaaa ttagtcttag tttgtgtctt
     9121 agccgctccc ttaagcgcct ctttgagata agcactcata gcagattctt cattaataat
     9181 cctgcaattt tttcaaacca agattttcaa actgcttttt cacatagtca ttcacatccg
     9241 actctaattt ccagtttact aacatattat tttctttcat taaaacactg tcgcttcttc
     9301 tagcgtaaac ttgacattat cttcaatcca tttacggcgt ggttctacct tatctcccat
     9361 gagaacattg acgcggcgtt cggcgcgcgc taaatcttca attgtgacac ggatgagggt
     9421 acgtgtttct gggttcatgg ttgtttccca gagctggtcc gcattcatct caccaagtcc
     9481 tttgtatcgt tggagggtag cgcctttacc gaactgttta cggagttctt ctagttctcc
     9541 gtccgtccaa gcgtaggcca cttcttcttt cttgccttta cctttggaca tcttataaag
     9601 aggtgggagg gcaatataga catgacctgc ctcgactagc ggacgcatgt aacggtagaa
     9661 aaatgtcaag agcaaggtct ggatatgggc accgtcggta tccgcatcgg tcatgataat
     9721 gatcttatca tagttggcat cttcaataga gaagtctgct ccaacacccg caccaatggt
     9781 ataaatcatg gtattaatct cttcattttt gaggatatcc gccatcttgg ccttggctgt
     9841 attgacaacc ttaccacgaa gaggtagaat agcctggaac ttgcggtcac gaccttgttt
     9901 ggcagaacca ccggcagagt ccccctcaac tagatagagt tcattcttag caggattctt
     9961 agattgggct ggggtcaatt tcccagacaa caagccctta tctttcttgt ttttcttccc
    10021 atttcggctc tcatcacgcg ccttacgtgc tgcttcacga gcatcacggg ccttgatagc
    10081 cttgcggatg aggttagaag ctaattcccc attttccata aggaaaaagg tcaacttatc
    10141 agccactatt ccatccacaa ctgggcgagc tagggggctt cctagtttat ccttggtctg
    10201 tccttcaaac tgcaagtgtt cttcaggaac taagatagaa agaacgaccg ctagtccctc
    10261 acgatagtct gaaccttcaa ggtttttatc tttttccttg agaagacctg ttttacgtgc
    10321 atagtcattc atgaccttgg taatggcaga cttgaatcct gtctcgtgcg ttccaccgtc
    10381 cttggtgcga acgttattga caaaggatag aatgttatct gagaatccgt cattgtactg
    10441 gagggctact tccacttgaa aaccattgtc ttccccttca aagtaaagaa ctggcgtcaa
    10501 gatttcctta tcttcgttga gataagaaac aaaatcttgt actccattct catagtggaa
    10561 ctcaatcgct tcatctgttc gcttgtccgt taaagacaag gtcacatttt tcaagagaaa
    10621 ggctgattca ttaaggcgct ctgaaatggt attgtacttg aaatctgtcg tagaaaagat
    10681 agtcgcgtca ggcataaaag taactttggt gcctgtttta gacttgggtg ctgtaccgat
    10741 tttcttcaaa gtcgtgacag gttttccacc attttcaaaa cgttgcttgt aaactgcgcc
    10801 atcacgggta atttcaactt ctaaccagct agaaagggcg ttaacaacgg aagaacccac
    10861 tccgtgaagt ccacctgatg tcttatagcc accttgaccg aatttccctc cggcatgaag
    10921 aatggtaaag ataacctcaa cagttggaat tcccatagcg tgcatacctg tcggcatccc
    10981 acgtccatgg tcttgaaccg ttagactacc gtctttattg atagttacat caatacgatc
    11041 accaaaccca gacaaggctt catcgactgc attatcaacg atttcccaaa ctaggtgatg
    11101 aagaccagcg ccatcggtcg atccaatata catccctgga cgttttcgga ccgcatccaa
    11161 cccttctagc acctgaatag catcatcatt ataattgtta atattgattt ccttttttga
    11221 cacaaggaac ctcctattcg ttcatcttta ctattctaca ggttttccaa ggattttgca
    11281 aaatttttct ttctccgatg tgacaatttc agcagagatt ctctgctttt ctttcccaat
    11341 tcatgatata ataggagtat gattacaata gttttattaa tcctagccta tctgctgggt
    11401 tcgattccat ctggtctctg gattggacaa gtattctttc aaatcaatct acgcgagcat
    11461 ggttctggta acactggaac gaccaacacc ttccgcattt taggtaagaa agctggtatg
    11521 gcaacctttg tgattgactt tttcaaagga accctagcaa cgctgcttcc gattattttt
    11581 catctacaag gcgtttctcc tctcatcttt ggacttttgg ctgttatcgg ccataccttc
    11641 cctatctttg caggatttaa aggtggtaag gctgtcgcaa ccagtgctgg agtgattttc
    11701 ggatttgcgc ctatcttctg tctctacctt gcgattatct tctttggagc tctctatctt
    11761 ggcagtatga tttcactgtc tagtgtcaca gcatcgatcg cggctgttat cggggttctg
    11821 ctctttccac tttttggttt tatcctgagt aactatgact ctctcttcat cgctattatc
    11881 ttagcacttg ctagtttgat tatcattcgt cataaggaca atatagctcg tatcaaaaat
    11941 aaaactgaaa atttggtccc ttggggattg aacctaaccc atcaagatcc taaaaaataa
    12001 aacgccagtt ctgtactgac cccaaa
//
LOCUS       DBERCW010000051        12009 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.051, whole genome shotgun sequence.
ACCESSION   DBERCW010000051 DBERCW010000000
VERSION     DBERCW010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12009
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.051"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(83..1084)
                     /locus_tag="ACL72M_001880"
                     /pseudo
     CDS             complement(83..1084)
                     /locus_tag="ACL72M_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            1380..1685
                     /locus_tag="ACL72M_001881"
                     /pseudo
     CDS             1380..1685
                     /locus_tag="ACL72M_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            1817..2761
                     /gene="manA"
                     /locus_tag="ACL72M_001882"
     CDS             1817..2761
                     /gene="manA"
                     /locus_tag="ACL72M_001882"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGS0716953.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(2783..4258)
                     /locus_tag="ACL72M_001883"
     CDS             complement(2783..4258)
                     /locus_tag="ACL72M_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGS0716954.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            4341..5095
                     /locus_tag="ACL72M_001884"
                     /pseudo
     CDS             4341..5095
                     /locus_tag="ACL72M_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(5115..5570)
                     /locus_tag="ACL72M_001885"
     CDS             complement(5115..5570)
                     /locus_tag="ACL72M_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS0716955.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(5590..6765)
                     /locus_tag="ACL72M_001886"
     CDS             complement(5590..6765)
                     /locus_tag="ACL72M_001886"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS0716956.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGSGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFTGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(6824..7669)
                     /locus_tag="ACL72M_001887"
     CDS             complement(6824..7669)
                     /locus_tag="ACL72M_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0716957.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            7794..8351
                     /locus_tag="ACL72M_001888"
     CDS             7794..8351
                     /locus_tag="ACL72M_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS0716958.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            8370..8837
                     /locus_tag="ACL72M_001889"
     CDS             8370..8837
                     /locus_tag="ACL72M_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGS0716959.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            8926..9555
                     /gene="upp"
                     /locus_tag="ACL72M_001890"
     CDS             8926..9555
                     /gene="upp"
                     /locus_tag="ACL72M_001890"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGS0716960.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            9729..10319
                     /gene="clpP"
                     /locus_tag="ACL72M_001891"
     CDS             9729..10319
                     /gene="clpP"
                     /locus_tag="ACL72M_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGS0716961.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            10398..10646
                     /locus_tag="ACL72M_001892"
     CDS             10398..10646
                     /locus_tag="ACL72M_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGS0716962.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            10747..11907
                     /locus_tag="ACL72M_001893"
     CDS             10747..11907
                     /locus_tag="ACL72M_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0716963.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
BASE COUNT         3767 a         2371 c         2512 g         3359 t
ORIGIN      
        1 tttaaaatag aaattgagaa tatgaactat tgaaagatcg gagcaatccg gtctttttat
       61 ataaagaaat tgcatataat actcatctgc tttcaaaaag cattctagtc catctccgat
      121 taacgatgga ctttatcacc tccttctcca gtccttgtat gacatcttga agttgattca
      181 tgacatcttc caaagttcga aaggccttat tcttaaatcc acgtttacga atctctttcc
      241 acacttgttc aatgggttca tctctggtgt gtatggagga ataaaggtaa aaccaatatt
      301 agtcggaatc tttaaggtac ttgatttatg ccatatagca ttgtccataa cgagtaaaag
      361 ataatcatct ggataagctt gtgaaagctc ttctaaaaag gcgttcatcc actcagtatt
      421 acatccacca gctattaaga aaaatgattc gcctgtatgg gcatcaacag ctccataaca
      481 atagtgaaat tctcgtatat agtgactatg gacatgtgga cctactccta ttggagccca
      541 acaagatccc agtttactga ttctaccgaa accagcctca tcttggtaca tcaagcgaac
      601 cttacgaaaa cgtctactgg ttttaaagcg ctttcttttc ttcttgaatt gagattttat
      661 ttttagacgc gacaatggtt tgagcgtctg ctttcctagg atgttctgga cgtggcataa
      721 tatttcgcca accatggtgc ttcaacagtt gatagaaggc atcacgtgtg taggaacgac
      781 ctaactcctt tttataagcc tgaaataagg catcaattgt aacaaattct cctgcctctg
      841 tagccttcaa atggcgggca agaaagactt tcttttcctc aatcgtcata tatgcatggt
      901 tacggccacc acgtgtttct tgaaggagag agtcgagttc gaactcctca tattttttta
      961 catttcgcca aatcgttgtt tgattacagt ctatagtgta ttgaatctat aacagtacac
     1021 cttagctgct aaaatatttc tataaattag tttgactttc ctgatagagt tgttcacatc
     1081 ttatttcaaa ctactataaa agttctataa tctctttata agatttgccc atcagacgaa
     1141 atataataaa ttgaaactag aatagtacac ctctacttct aaaacattgt tagaaatcga
     1201 tttgactgtc ctgatcgatt tgccctgttc ttgtttcgtt ttactataga acgatttgaa
     1261 ggcgtttatg atatttagct gtacgagagt ctttaaaaag tgttttgatg gtttggattt
     1321 cttctttagt tgatttcata tcactattat ataatgcttt ttgattttag tatagtatta
     1381 tcgtagaaaa tggactcggt gctatggata caccggatga gaatggttat gtagcagatg
     1441 actatcggat tacttactta gaggcccaca tcaaggccat gcgagatgcc atttacaaag
     1501 acggggttga cttgcttggt tatacgacat ggggctgtat cgattcggtt tcagctggca
     1561 caggggaaat gaataagcgc tatggtttta tctatgtaga tcgagataat gtaggaaatg
     1621 ggactctcaa acgtagcaag aagaagtcct tctattggta catgtcattt atagcaatgg
     1681 tgtaagcatc gagtagagca catttgttta ctatttttat aaaatcttct ccctgcttta
     1741 taagatgtaa aaaagagttc aattcgaact ctttttttgc tataatgagg ggagaaaaat
     1801 cagacaggag attaagatgt cagaaccatt atttttacaa tcagttatgc aagaaaaaat
     1861 ctggggtggt accaagctac gtgatgagtt tggctacgac atcccaagtg aaaaagtcgg
     1921 agagtactgg gctatctcag ctcatctaaa tggtgtttct aaagttgcca atggtcgtta
     1981 cgagggaaca gatcttgcta ctttgtatgc ggaacaccgt gaattatttg gcaatcgtcc
     2041 tgagcctgta tttccgcttt tgactaagat tttggatgct aacgactggc tcagcgttca
     2101 agttcaccca gacgatgctt atggactaga gcatgaaggc gaacttggaa aaacagaatg
     2161 ctggtacatc atcgctgcgg atgaaggttc agagattatc tacggccaca atgccaagtc
     2221 aaaagaagaa ctccgccagc aaatcgagga taagaactgg gatgcgctgt tgacaaaagt
     2281 gccagttaaa gcaggagatt tcttctatgt accaagcggt accatgcacg ctatcggggc
     2341 gggtatcttg attcttgaaa cccagcagtc tagcgatacc acttaccgtg tctatgactt
     2401 tgaccgtaag gatgacaagg gcaatttacg tgaacttcac cttgaaaaat ctatcgatgt
     2461 cttgaacatt ggtgaacccg caaatagccg tccagtgaca atcaaagcag atgatctacg
     2521 ttccactctc cttgtatcca atgatttctt cgcagtttac aaatgggaaa ttactggaaa
     2581 agttaacttt gaaaagacag ctgactacag cttgttgagt gtcttggctg gtcaaggtca
     2641 actaactgtt gacgggaaaa actatccaat ccaaaaaggg agacacttta tcctaccaag
     2701 tgatgttgaa gcttggactc tggaagggca agatttagaa ttaattgtta gtcatccata
     2761 aaaaagaaag ggcctgagtt cattactcaa gtcctttttg attacataaa ttgggcgatg
     2821 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     2881 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     2941 ttttaaagat atagcctgta aaaagtgaaa ggtagagagc tccaaatggc atgaggagat
     3001 tgggaaccaa gaagttcata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     3061 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt cctaaaataa
     3121 cactccattt ggcacgtttg ctgttatcct ggttggtgat attgcccaca ttgatctcca
     3181 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     3241 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caagctcggt cccccttcag
     3301 actggatatt gaagggggac cgagcttgga aaatggctag acctgccatg atggatatcg
     3361 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     3421 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     3481 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     3541 ccccttccat ggcatttggc aaactgagag agcgaccgat gataacaaca aagatgataa
     3601 agagcagggg catcatgact ttcgaagctc tttcaatccc tttttgaacc ccacgtgata
     3661 caataaagat atttaataag ataaaggctg cttgagctcc tagggcaatg gctggatttg
     3721 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     3781 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     3841 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     3901 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     3961 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     4021 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atgaccgagc
     4081 cagcagatgc tagaataaag ccaagtttcg acccccattg tgatttttct gacatagtta
     4141 aactctgatc tcctttttca aaataagaaa aagctacttg agttgtcaaa tagccttctg
     4201 tttgattgat agacttgact atcctattat gttttctaag gtctgtcaag aaaacaattt
     4261 tcaagttttc acacctttct caaaaacgct tgactctgac ctaaggggag gggttatact
     4321 atcattgtaa ggaggaaatc atgtaccata taaaagaagc tgcgcagctt tcaggtgtct
     4381 ctgtcaagac cctgccctgc atcactatga caagatagga ctcttggtcc ccttaaagtc
     4441 ggaaaacggc tatcgaacct atagtcaaga ggatttggaa cgccttcagg tcattcttta
     4501 ctacaaatat ctaggctttt ctttagagaa aatagcagaa ctgttaaagg aagaaaggac
     4561 agatttattg ctccatttga ctaggtagtt ggactatcta actcgcgaaa ggcaacatct
     4621 ggataccttg atttccacct tgcaaaaaac tattcaagaa caaaaaggag aaagaaaaat
     4681 gaccattgag gaaaaattca cgggatttag ctatcaagac aatcaaaaat accaccaaga
     4741 agcggtagag aaatatggtc aagaagtcat gggacaagcg ctcgaacgcc aaaaaggtca
     4801 cgaagacgag gctacggccg cctttaacca agtctttcaa actttggcac aaaatcttca
     4861 agttggttta cctgcaacag caaccgaaaa ccaggagcaa gcagccaagc tcttgcaagc
     4921 cattcgcact tatggatttg actgctctat tgaggtattc ggtcatatcg gtaaaggtta
     4981 cgtctacaac ccagagttta aggaaaacat tgacaagttt ggttctgaaa cagcccagta
     5041 cacgtcagat gccattgcgg cttacgttca gacaaatgca gaaaaaatag gctaggaatt
     5101 tcctagccta ttttttactt caaatcataa agccagtcgt caccgttttt gtagtaaaag
     5161 aattcactga gatcttcttc tagaaacaca cgaagcatat cagacatatc atcggttgca
     5221 agttttagat gagaaagatt ttcaaagtcc tcccaccaaa ctttcccttc gtctgaagac
     5281 tggagttcac cagtaaagtg ttctgtcttg taaaaaagga cgacataacg ataatccttg
     5341 tcgtcatacc agtttttgat accacagagt tggggtttgg aaatgatcag accagtttct
     5401 tctttcactt cacgaatgac agcatcgaca aaggattcgc cacgttcaac atgaccacca
     5461 ggaaaagtaa tgccagacca gtcgggacta actcggtctt ggaccaggac cttatctccg
     5521 tttttaatca tacacatgtt aacaaattcg actgcctctc ttctgttcat tcttcacaac
     5581 ctttaatctt taatcataat gcagacttcc cgccacccag ccggtacaga gggcagaagt
     5641 gatgttaaag ccacccgtgt gggcattgat atccataact tcgcctgtaa agtggaggcc
     5701 aggtaccagc ttactttcaa gggttttagg attgatttcc ttgagactga ctccaccctt
     5761 ggtaacaaag gactttgcaa gggacatttt tccagttaca ggaattttaa gttctttaat
     5821 ggactggaca agttgttctc gttccttttc agtcagttgt ttgacttttt caggatatcc
     5881 ttgtacaaaa aattcggcca agcgttctgg taacaaggtt tttaaagcgt ttttcaagga
     5941 tttttcccga ttttcttcta gaaatgtaac caagtccttc tcagaaagtt gaggcaaaac
     6001 atcgagtgag agaacctccc cacctttgac aaagctagac atgcgtaggg cagcaggacc
     6061 tgacaaacca aagtgggtaa agagtaaatc atgagtgatg acatgcttac cataacttag
     6121 ggtcacatcg tccagagaaa tcccttgtaa ggctttatgt ggaaaatctg ttaataaagg
     6181 actttcagca gcctcaagat cggtgatggt atgcttaaaa tggcgagcaa tctcgtgacc
     6241 aaaaccagtc gaaccagtcg aaggataaga cttaccacct gttgtgacaa tgagtttctc
     6301 acaagtgaag gtttgatccg ctgacttaag gacaaactgg tcatctactt ttttaacaga
     6361 aacgatttct atttgagtag caacttgacc acctagttcg gtgattttct tttccaaagc
     6421 ttcgataata gtccgagact tgtcactggc tggaaagacg cgtccgtggt cttcgacctt
     6481 aagtttaaca ccattttctg taaaaaagtt gatgatgtca tgattatcga actgggagaa
     6541 aacactgtaa agaaagcgtc cgcttccagg aattccagct agcaggttgt ctaagctacc
     6601 attgttggtc acattgcaac gtcccccacc agtcccagct aatttttttc caagtttccg
     6661 atttttttcg atgaggaggg ttttctgtcc ataaaagcta ctggaaatcg tagccatcat
     6721 accagcaggt cccccaccga tgacaatagt atcaaaatgt ttcatagctc tattgtacca
     6781 caaaaaaaca agagatgatg gtcacctctt gtcaagaatg caattaatca atttcatagc
     6841 ccatcagcaa accgccctct tctgcataga aactgcagag accagaggtt ggtagaattt
     6901 taatatccgc ttgtgggaag gtttcacgga ttcgctctga gagctgttga caacattttt
     6961 cgttattgcg ttgggccatg acaatacggc caccagcata tccagctttt actaactcat
     7021 cataggcagc ttgaactgat ttctttgatc cccttgcttt ttgtagcaat tcgagagttc
     7081 cagtttcact agcttttccg accatacgaa tgttgagaag gccaacgacc gtaccgataa
     7141 gcttgctcaa acggccgttc ttcaccaagt tatcgacttt ggctaggaca aagagcaact
     7201 tagttttttc ttgataggca gtgatagctt caaccacttc ttcaaaagac aagccctggt
     7261 caatcaagtc attcaatttt tctacgagta ggtcaacttc accaccagca gataaactat
     7321 caatcacatg aatcttagtg tcaggatggt cttctagata aatattcttt gctagttgag
     7381 cactattgtg actgccagaa agggtacctg tgatggttac taggaaaatg tttttggcac
     7441 cttcaaatgc tcgcaaatag tcatctgggc ttggacaagc cgattttgaa gcttctgcag
     7501 ttgcatacat ggtttccatc atttggtcaa tatcgagact ggcgtcatca acaaagacct
     7561 gatcagctac ttgaatggtt aaggggacac ttacaaaggt tgtgttaata gctggtgttg
     7621 gcagttgacg ataatcacaa ccagagtcag caataatttt ccaagtcata gaaattctcc
     7681 atctttgtca gttatacatt gacaaaggtt ctgtcttttt ttacaattat atcatgaaaa
     7741 cccttgaaac aaaagcatca tccgtctgtt gtgacaagta gaaagaaaat gttatgtctg
     7801 aacgtagaat ctctgaaaag tctcttgaaa atctcagaaa atcaaaccaa gaatccaatt
     7861 tattaaccag agaagccatt gaaacagccc tcttgcaact cttggaaaaa aaggagctga
     7921 ccaagattag tatttctgaa ttggtcaaac gtgcaggtgt ttcgcgtgcg gccttttatc
     7981 gcaattatga ctccaaagag gaaattttag agagcgtctt taaacgaact gtccacaata
     8041 ttatggaaca gctgcatcat tacgatttaa agacagacct ttatttggtt tgggttcacc
     8101 ttttccggga ggccagaaag gaagctagag tgattcaatt ggccttggat taccatctgg
     8161 aaaaaatctt tgtccaagcc atgcaggaat ttctagaaaa ataccatggg aaatcaaaag
     8221 gtgtcagctc ttatcttcat tccttctgga gctcagccat cgtctctgtc cttctaaaat
     8281 ggatcaagga tggcatgaag gtaccagctg aaaagattgc agatttaggt ttaccatttt
     8341 ttaaaaaata gagaaaaagg agaaaagaga tgactgaaaa aagactggcc tgggatgagt
     8401 attttgcagc ccaagcccta ctaattgcga atcgttccac ttgtaaacgt gctaaagtgg
     8461 gcgcgattct ggtaaaagat aataaggtta tttccactgg ttacaatggt tcggtgtcag
     8521 ggactgagca ttgtattgat cacgaatgtt tggtcattga aggccactgt gttcgcaccc
     8581 ttcacgctga ggtcaatgct atccttcaag gtgctgagcg tggtgttccc aaaggcttta
     8641 cagcctatgt aacccatttt ccttgtctca actgtacaaa acaattgctt caggtcggct
     8701 gcaagcgcgt ggtttatatc aaccagtacc gaatggacga ctacgcccaa tacctttatc
     8761 aagaaaaagg gacagaattg acccatttac cacttgagac agtacagaca gctcttaaag
     8821 aggctgatct aatgtaaaaa ttatcaaaaa taaatggctt agaaagattt ttaaaccgtt
     8881 ttttggtata ataagaagaa taaattgaaa gaaggaattc caaaaatggg aaaaattgaa
     8941 gttattaatc acccactgat tcaacacaaa ttgtcaatct tgcgtcgtac agatacttct
     9001 acaaaagctt ttcgtgagct agtagatgag attgcaatgt tgatggggta tgaagtactt
     9061 cgtgatcttc cactagaaga tgtggaaatc gaaacaccaa ttacaaaaac agttcaaaaa
     9121 caattggcag gtaagaaatt ggccatcgtc ccaatcttgc gtgcaggtat cgggatggtt
     9181 gatggtctct tgagcttggt tccagctgct aaagttggcc acatcggtat gtaccgtgat
     9241 gaagaaacac ttcaaccagt tgaatacttg gtgaaattgc ctgaggacat tgaccaacgt
     9301 caaattttta tagtagaccc aatgttggca acaggtggct cagcaatctt ggctgttgat
     9361 tctcttaaaa aacgtggcgc atcaaatatc aaatttgtct gccttgtatc tgctccagag
     9421 ggtgtaaaag cccttcaaga agctcatcca gatgtagaaa tctttacagc agccttggat
     9481 gaacgtttga acgaacacgg ttatatcgtt ccaggtcttg gagatgctgg agaccgcttg
     9541 ttcggtacaa aataagatcg aaaagaagaa tgacttggaa aagtatttcc agtcacgaaa
     9601 ggaggttggg tttttgtttc tgtctaatga aagcagagca aaaatttgac cttttttgac
     9661 caagatatta taatagtctt atcttcagtc atttgaccaa caaaattaaa actcaaaagg
     9721 agaaatgaat gattcctgta gttattgaac aaacaagccg tggagaacgt tcttacgata
     9781 tttactcacg tcttctcaaa gaccgcatca ttatgctgac aggtccggtt gaagacaata
     9841 tggctaactc tgttattgcc caattgcttt tcttggatgc ccaagatagt acaaaagata
     9901 tttaccttta tgtcaataca ccaggtggtt ctgtttcagc tggtttggca atcgtagata
     9961 ccatgaactt tatcaaggca gatgtccaaa ccattgttat gggaatggct gcatctatgg
    10021 gaacagtcat cgcatcaagt ggagcaaaag gcaaacgttt catgcttcca aatgctgaat
    10081 acatgattca ccaaccaatg ggcggtacag gtggtggtac ccaacaaact gatatggcta
    10141 tcgctgcaga acacttgctc aaaactcgta ataccttgga aaaaatcttg gctgaaaatt
    10201 caggtcagtc aatggaaaaa gtccatgcag atgcagaacg tgataactgg atgagcgccc
    10261 aggaaacact tgaatatggc tttattgatg aaattatggc caacaattca ttgaactaat
    10321 gatgatagaa ggcaaactcg actgggtttg ctttttttgg tataataggg agagatttct
    10381 tagaaagagg atttatcatg tttgaaaaag tcaatcgctc tggcttgatt atctatcttt
    10441 actataatcg tgatgccaaa aaactgcagg attatggaga tattacctat cattccaaga
    10501 aacatcgtta cttacaactc tatgttccaa ctcaagaagt ggagcaattg gtcggacgct
    10561 tgagcaagga aaaatttatt aaaaaagtta gggtttgtca tatccaagag ttggaaacac
    10621 cctttgtggg caatctttat cgataggaaa acgttatcat cgaaaaagtt caaggaaaac
    10681 attgacaatt ttctgataat tcggtatatt cttaacagac tatttaagaa ataaggagac
    10741 aaaaagatga agaaaaaatt tgccctatcg tttgtggcgc ttgcaagtgt agcacttctt
    10801 gcagcctgtg gagaagtgaa gtctggagca gtcaacactg ctggtaactc agtagaggaa
    10861 aagacaatta aaatcgggtt taactttgaa gaatcaggtt ctttagctgc atacggaaca
    10921 gctgaacaaa aaggtgccca attggctgtt gatgaaatca atgccgcagg tggtatcgat
    10981 ggaaaacaaa tcgaagtagt cgataaagat aataagtctg aaacagctga ggctgcttca
    11041 gttacaacta accttgtaac ccaatctaaa gtatcagcag tcgtaggacc tgcaacatct
    11101 ggtgcgactg cagctgcggt agcgaacgct acaaaagcag gtgttccctt gatctcacca
    11161 agtgcgactc aagatggatt gactaaaggt caagattacc tctttattgg aactttccaa
    11221 gatagcttcc aaggaaaaat tatctcaaac tatgtttctg aaaaattaaa tgctaagaaa
    11281 gttgttcttt acactgacaa tgccagtgac tatgctaaag ggattgccaa atctttccgc
    11341 gagtcataca agggtgaaat cgttgcagat gaaactttcg tagcaggtga cacagacttc
    11401 caagcagccc ttacaaaaat gaaagggaaa gactttgatg ctatcgttgt tcctggttac
    11461 tataatgagg ctggtaagat tgtaaaccaa gcgcgtggta tgggaattga caaaccaatc
    11521 gttggtggtg atggattcaa cggtgaggag tttgtacaac aagcaactgc tgaaaaagca
    11581 tcaaacatct actttatctc aggcttctca actactgtag aagtttcagc taaagctaaa
    11641 gccttccttg acgcttaccg tgctaagtac aatgaagagc cttcaacatt tgcagccttg
    11701 gcttatgatt cagttcacct tgtagcaaac gcagcaaaag gtgctaaaaa ttcaggtgaa
    11761 atcaaggata accttgctaa aacaaaagat tttgaaggtg taactggtca aacaagcttc
    11821 gatgcagacc acaacacagt caaaactgct tacatgatga ccatgaacaa tggtaaagtt
    11881 gaagcagcag aagttgtaaa accataatag aaaaatgttg aaatagggaa tgagcctttg
    11941 actcactccc tgtttcgata tttaatactc ttcgaaaatc tcttcaaact gcgtcaacgt
    12001 cgccttgga
//
LOCUS       DBERCW010000052        11926 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.052, whole genome shotgun sequence.
ACCESSION   DBERCW010000052 DBERCW010000000
VERSION     DBERCW010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.052"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..183
                     /locus_tag="ACL72M_001894"
     CDS             <1..183
                     /locus_tag="ACL72M_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS0716964.1"
                     /translation="LTVEDKACNHALSKERSKVENIFAKVKTFKIISTTYRNHRKRFG
                     LRMNLSAGIINHELGF"
     gene            374..2665
                     /gene="pcrA"
                     /locus_tag="ACL72M_001895"
     CDS             374..2665
                     /gene="pcrA"
                     /locus_tag="ACL72M_001895"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGS0716965.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNNLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNVQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2708..3388
                     /gene="radC"
                     /locus_tag="ACL72M_001896"
     CDS             2708..3388
                     /gene="radC"
                     /locus_tag="ACL72M_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGS0716966.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3385..4074)
                     /locus_tag="ACL72M_001897"
     CDS             complement(3385..4074)
                     /locus_tag="ACL72M_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS0716967.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4092..4733)
                     /locus_tag="ACL72M_001898"
     CDS             complement(4092..4733)
                     /locus_tag="ACL72M_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGS0716968.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4816..5031)
                     /locus_tag="ACL72M_001899"
     CDS             complement(4816..5031)
                     /locus_tag="ACL72M_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS0716969.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5039..5386)
                     /locus_tag="ACL72M_001900"
     CDS             complement(5039..5386)
                     /locus_tag="ACL72M_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGS0716970.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5391..6506)
                     /locus_tag="ACL72M_001901"
     CDS             complement(5391..6506)
                     /locus_tag="ACL72M_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS0716971.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6516..7475)
                     /locus_tag="ACL72M_001902"
     CDS             complement(6516..7475)
                     /locus_tag="ACL72M_001902"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS0716972.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7588..8157)
                     /locus_tag="ACL72M_001903"
     CDS             complement(7588..8157)
                     /locus_tag="ACL72M_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGS0716973.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8285..8956
                     /locus_tag="ACL72M_001904"
     CDS             8285..8956
                     /locus_tag="ACL72M_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGS0716974.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8940..9758
                     /locus_tag="ACL72M_001905"
     CDS             8940..9758
                     /locus_tag="ACL72M_001905"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGS0716975.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9755..10651
                     /locus_tag="ACL72M_001906"
     CDS             9755..10651
                     /locus_tag="ACL72M_001906"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0716976.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10695..11669
                     /gene="pta"
                     /locus_tag="ACL72M_001907"
     CDS             10695..11669
                     /gene="pta"
                     /locus_tag="ACL72M_001907"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGS0716977.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3481 a         2285 c         2570 g         3590 t
ORIGIN      
        1 ctaacagttg aagataaagc ctgtaaccat gcgctatcca aggagagaag caaggttgag
       61 aacatctttg ccaaagtaaa aacgtttaaa ataatttcaa caacctatcg aaatcatcgt
      121 aaacgcttcg gattacgaat gaatttgagt gctggtatta tcaatcatga actaggattc
      181 tagttttgca ggaagtctat tgaggtattg agctagttta tgaaaaaatt gggtgaaaag
      241 tcgagtgttt tagaaaccca cagtgtagta ttctagtttc aatccactat attttgctac
      301 tccccgtaaa gtttctattt tccctgattt ctgatataat agaaatattg acttcaagag
      361 taaggaagag aagatgaacg cattattaaa tggaatgaat gaccgtcagg ctgaggcggt
      421 gcaaacgaca gaaggtccct tgctaatcat ggcaggggct ggttctggaa agactcgtgt
      481 tttaacccac cgtatcgctt atttgattga tgaaaagctg gtcaatcctt ggaatatctt
      541 ggccattacc tttaccaaca aggctgcgcg tgagatgaaa gagcgtgctt atagcctcaa
      601 tccagctact caggactgtc tgattgcgac cttccactcc atgtgtgtgc gtattttgcg
      661 tcgcgatgcg gaccatattg gctacaatcg taattttaca attgtggatc ctggtgaaca
      721 gcgaacgctc atgaaacgta ttctcaaaca gttgaacttg gatcctaaaa aatggaatga
      781 acgaactatt ttggggacca tttccaatgc taagaataat ttgattgatg atgttgctta
      841 tgctgcccaa gctggcgata tgtatacgca aattgtggcc cagtgttata cagcctatca
      901 aaaagaactt cgtcagtctg aatccgttga ctttgatgat ttgattatgc tgaccttgcg
      961 tctctttgat caaaatcctg atgttttgac ctactaccag caaaaattcc aatacatcca
     1021 cgttgatgag taccaagata ccaaccacgc tcagtaccaa ttggtcaaac tcttggcttc
     1081 ccgttttaaa aatatctgtg tggttgggga tgcggaccag tctatctacg gttggcgtgg
     1141 tgctgatatg cagaatatct tggactttga aaaggattac cccaaagcca aggttgtctt
     1201 gctggaggaa aattaccgct caaccaaaac cattctccaa gcggccaacg aggttattaa
     1261 aaataataaa aatcgccgtc ctaaaaatct ctggactcaa aacgctgatg gggagcaaat
     1321 cgtttactat cgtgccgatg atgagctgga tgaggctgta tttgtagcca gaaccatcga
     1381 tgaacttagt cgcagtcaaa acttccttca taaggatttt gcagttctct atcggactaa
     1441 tgcccagtcc cgtacaattg aggaagccct gctcaagtct aacattcctt ataccatggt
     1501 tggcggaacc aaattctaca gccgtaagga aattcgcgat attattgctt atctcaacct
     1561 tattgctaat ttgagtgaca atattagttt tgagcgtatt atcaacgagc ctaaacgtgg
     1621 aattggtcta ggtacagttg agaaaatccg tgattttgca aatttgcaaa atatgtctat
     1681 gctggatgct tctgctaata ttatgttgtc tggtatcaag ggtaaggcag cccaatctat
     1741 ctgggatttt gccaatatga tgcttgattt gcgggagcag ctagaccact taagcattac
     1801 agagttggtt gagtccgtcc tagaaaaaac aggttatgtc gatattctta acgtccaagc
     1861 gactctagaa agcaaggcac gggttgaaaa tatcgaagag tttctttctg ttacgaagaa
     1921 ctttgatgac accacggatg tgacagaaga ggaaactggt ctggacaaac tgagtcgttt
     1981 cttaaatgac ttggctttga ttgccgacac agattcaggt agtcaggaga catcagaagt
     2041 gaccttgatg accctgcatg ctgccaaagg tctcgaattt ccagttgtct ttttgattgg
     2101 gatggaagaa aatgtctttc cacttagtcg tgcgactgaa gatccagatg aattagaaga
     2161 agagcgccgt ctagcctatg taggtatcac gcgtgcagag aaaattctct atctgaccaa
     2221 tgccaactca cgcttgcttt ttggtcgtac caattataac cgtccgactc gttttattaa
     2281 cgaaatcagt tcagacttgc ttgagtatca aggtctggct cgtcctgcaa atacaagctt
     2341 taaggcatca tatagcagtg gtagtatttc ctttggtcaa ggtatgagtt tggctcaggc
     2401 tcttcaagac cgtaaacgcg gtgctgcccc aaaatcaatc cagtcaagcg gtcttccatt
     2461 tggtcaattt acagctggcg caaaaccagc atctagcgag gcaaattggt ccattggtga
     2521 tattgctctc cacaagaaat ggggagaggg aaccgttctg gaagtttcag gtagcggtgc
     2581 taggcaggaa ttgaaaatca atttcccaga agtaggtttg aaaaaacttt tagccagtgt
     2641 ggctccaatt gagaaaaaaa tctaattttc catccttctc acgaataata aagtgaggag
     2701 gatttttatg tacagtattt cattccaaga agattcacta ttaccaagag aaaggctggc
     2761 caaggaagga gttgaagcgc ttagtaacca agagttgcta gctattttac tcaggacagg
     2821 aacacgtcaa gttagcgttt ttgaaattgc ccaaaaagtc ttgaacaatc tttcaagcct
     2881 aacggatttg aaaaaaatga ccctgcagga attgcagagt ttgtctggta ttgggcgtgt
     2941 taaggccata gaattacaag ctatgattga actggggcat cgtattcaca aacacgagac
     3001 tcttgaaatg gaaagtattc tcagcagtca aaagttggcc aagaagatgc agcaggaatt
     3061 aggggataaa aaacaagagc acctggtggc actctatctc aatactcaaa atcaaatcat
     3121 ccatcagcag accattttta tcgggtctgt aactcgtagt atcgctgaac cgcgagagat
     3181 tcttcactat gcaatcaagc atatggcgac ttctcttatc ttggtccaca atcatccttc
     3241 aggagcggta gcgcctagcc aaaatgatga tcatgtcact aaacttgtta aagaagcctg
     3301 cgaattgatg gggattgttc tcttggacca tttgattgtc tctcattcta attactttag
     3361 ttatcgtgaa aagacagatt taatctaaag ttcattaacg acatagtcaa agagtttttt
     3421 atctttggga cgattttcaa aaagaagttc tggatgccat tggacaccga gaaaggcgac
     3481 atcatccgta ctcatgacag cctcaatgat accatcttta ggatcatgag ccacaacttt
     3541 taaatttggt gctaagtcct tgatgctctg gtggtggaag gagttgatat gagagatttc
     3601 tccatagatt tcttggagaa cggtatctgg ttctgttacc aagcgttgag ttgtgtactc
     3661 aacagaagaa tcctgccaat ggtcttcgat atcttggtac aaagttccac ccatggcaac
     3721 gttaaagagt tgggtaccac ggcagacaga gaaaatgggc tttttctgtt taatagcttc
     3781 cttgatgagg gtcagttcga agatatctct ttgaaggtga tagtcatcgc tatcaatggt
     3841 tttgggttcg ccataaaatt ttggatcgac attttgccca cctgtcaaga tgagcttgtc
     3901 aatcaaactg atatagtggc aggccatttc ttgatcacca atcggtagga tgatgggaat
     3961 ccctccagca tctttaacgc cttcaacaaa gccttttgct gcgtagctca tcatgatgtc
     4021 atcatctgga tgagcttttt cgtttcctgt aatcccaata actggttttt tcataaaatg
     4081 attttcgctt tctaatcctc ttttcgcatg aagtagagga gggtttggag ttcacttgtc
     4141 aaatcgacat actgaacgac cacgtctttt ggtaaatgca gatggactgg tgaaaaactg
     4201 agaattcctt tcacaccagc atcaaccaag agattagcaa cctcttgtga cttgacgctg
     4261 ggaacagtta ggatagcagt cttcacatca gcatccttga ttttatcctt gatctgagaa
     4321 atcccgtaaa tgggaatccc gtcaggagtt tgggtaccga cttcaggatg gtcgtctagg
     4381 tcaaaggcca tgataatctt catcttgtta cgttcgtgga agcggtagtg gagaagggca
     4441 tggcccatat ttccaatacc aaccagcatg acattggtaa tagagttgtc attgagcaaa
     4501 tcggcaaaaa atgtcattag ttttttgaca tcatagccaa aaccacgacg accaagttca
     4561 ccaaaatagg aaaaatcacg acgtacggtc gctgaatcaa taccgatagc ctctgcaatt
     4621 tgcttagagt tggcacgttc aatcttttct gcatgaaatc tcttaaaaat tcgatagtag
     4681 agagagagtc tttttgctgt agcttttgga atagcaaact gtttatcttt cacaaaatca
     4741 caacctttct attcttctat tttatagaaa cattgtgaaa aaatcaacaa aaataagaaa
     4801 aaactaagaa aaatcttagt tttgatgtaa aaaatctgca tgagatagaa aacggtagag
     4861 gtctccgacc agaccctgat aaactttttg gcccctaaaa gtcagagaag tcacataaag
     4921 tgtatctggt aaggttacac atcctgacaa agtcaacatg agagcctcat gatcctcata
     4981 cttgagagta cgctctacat gatagcagtc cttataggtc agttcaaaca ttttggctct
     5041 atctttccga ttttgtaaag acaccacgtt ctaccaagct atccatgagg aagtagaatt
     5101 tttcctgatg aatatggtgg tcttctgatt tgaaaatatc aactagacga aggccaaact
     5161 tgtcagtgat attgatttta gcccctgtaa gttccttgtt aatgatgatt ttgagttgga
     5221 agccttcacc gctgtttggc actttttcca aaaggcgagt cagttcatag ttaccaacct
     5281 tagtttcaaa aaaggtgtta tctttgaggg tgaatttttt aacagaaggg ctaagagtgt
     5341 aatcgtaacg acaatttttt aactgaatga ttttttcaaa tgccatatgg ctaacctccg
     5401 ataatttctt ttaaggtttt tgcgagggtt tgtaggtctt caacggtatt ttgtggcgac
     5461 aaactgatgc gaagggattc cttcaagcgt tctgaatttg cgccatacat ggcttcaaga
     5521 acatggctgg attggacaac gcctgcagta caggctgagc cagtagagat tgaaattcca
     5581 gctaaatcta gccgaaggag taagaggtca tttttctgac caggaaatcc aatattgaga
     5641 acataaggga gatgatgttt tcctctattc aagtaatact gaatgccctc cagctctgcc
     5701 agaaaggcag tttctagatt ttgtacatgt tgaaaatgtt cttcttgttt ttctaggtct
     5761 tcttttaggg ctgcaaccat gcctacgata gcaggcagat tttcagttcc tgcacgtttt
     5821 ttctgttcct ggtctccgcc atgtagatag gaatcaaagt ccatgctaga tgcgtagaga
     5881 aaaccgattc ccttaggacc atggaatttg tgggcagaag cagtgagaaa atcaatgccc
     5941 aattcttctg aatgaattgg gattttacca atagcctgaa ctgcatcaac atgataggca
     6001 gcagggtgtt gcttgagtat ttggccaatt tcagcgatgg gcagtaggtt tcctgtctca
     6061 ttattggcaa acatggtaga aaccaaaatc gtatcgtcac gtaaagcctt ttgaatttgc
     6121 tgggctgtga tttcttgatt ttctggctgg ataatggttg cttcaaaccc aaagtgttga
     6181 accaagtaat caattgtttc aaggacagca tggtgctcga tggcagttgt gatgatatgt
     6241 tttccttgtt cttggtgacg aagacagtag ccaatgatgg tagtattatt gccttcagtc
     6301 ccaccagaag tgaaaaagat atgttgaggt tttgtcctta gtaactgggc tagttcctga
     6361 cgggcttctc gcaagagttt gccagcttga cgaccatgac catgaatact agaaggattt
     6421 ccgtgggttt cttgcataac cttggtcata gctgaaatag caactgctga cataggagtc
     6481 gttgcagcat tgtccaaata aatcaaagaa tcaccttatt tctttttatt gtaggcaaag
     6541 agtgggctga ctggttttct ttcgtgaata cggacgatag catcaccaat taactcacta
     6601 gcagtgatgt agcatacatt tttaggagtt ttttcttttg ttgctactga atcagtcaca
     6661 agaatttctt taatattagt attgtcaaga agctcagcag ctccctcgac gaagagaccg
     6721 tggctagaaa cagcataaat ttctgtagct ccttcacgtt caacgatttt agaagcttca
     6781 gagaaggtac gtcctgtatt taaaatatca tcaatcaaga tagctttctt accttcaaca
     6841 tcaccaataa tataaccttc gttacgagtt gcatcgtctt gagggtagtc gataatggcg
     6901 ataggagcat caagatattc agccaggcta cgcgcacgtt tgacacctga atttttaggg
     6961 ctaacgacaa caacatctga accaagcaat cctttatcgc agtaatgttt tgcgaatagg
     7021 ggaacagtga aaagattatc cactggaata tcaaagaaac cttgaacctg aacggcatgc
     7081 aaatcaagag tcaggatacg atcaactcca gccttaacca gcatattggc aactagtttt
     7141 gctgtaagtg gctcacgagg acaagcaatg cggtcttgac gtgcatagcc aaaatatgga
     7201 aggacaacgt tgatactgtg ggcacttgca cgcacacaag catcgaccat gattaacaat
     7261 tccattaggt ggttgttgac agggaaactt gttgattgga tgatgtaaac atcataacca
     7321 cggacacttt cttcgatatt tacttggatt tctccgtctg aaaattgacg tgatgatagt
     7381 tttccaagtg ggacaccaac agcttgggca attttttgtg caatctcttg gttagagttg
     7441 agtgcgaaaa gtttcatgtt ttttctatct gacattatag accgtcctct gtaaacttta
     7501 taaatcctag ttatatttac cttacatata tgaactggga tttgtgtatt tttatctttt
     7561 ctattttacc aaaaaatgga gattatttca gctatttttc atacttttga caaatcgaac
     7621 caattttgaa ggagcttttt ggtaggaaat ctgatttttc tctaaaaatt gtcggaaatc
     7681 ctgtttgcct tgctcatgat tttccacttc aagctccaat tcgtaatctg ttatatcaaa
     7741 gtatcggctc tgatccagtg ccatgagacc aatagctgtt ttcatttcat agcgaagcgt
     7801 tgttagacaa ccaagaacct gccagttctt actttggata ccatgtttcg ccaattcatc
     7861 cagtactagc ccttgaggaa gttcttcctt actcagatag ttctcagcat cttttagttg
     7921 caatttttgg ttgtattcca tgtttccaac actctgcggg actttgagtg tcaactcagc
     7981 ccagtcttca aaggttcgaa tgcgcatagc gactttcttt tctcgcagtt caaaatcagg
     8041 cgtgtcgatg tagtaatttg tttgaagaac aggagtgaca cctgtgaact ggtcttttag
     8101 acgattgtat tcatcttttt tcaatagtgt tttcaattca atttctaaat gtttcatttt
     8161 tcttaccttt ttttatcgtt gaaagcggat ttatggtata ataagcattg tatttattgt
     8221 atatgaatct ggagaaaaaa tcaaagatat ttttgacgga taatatgaga acaagggaga
     8281 atatatgacc ttagaatggg aagaatttct agatccttac attcaagctg ttggtgagtt
     8341 aaagattaaa cttcgtggta ttcgtaagca atatcgtaag caaaataagc attctccaat
     8401 tgagtttgtg accggtcgag ttaagccaat tgagagcatc aaagaaaaaa tggctcgtcg
     8461 tggcattact tatgcgacct tggaacacga tttgcaggat attgctggct tacgtgtgat
     8521 ggttcagttt gtagatgacg tcaaggaagt agtggatatt ttgcacaagc gtcaggatat
     8581 gcgaatcata caggagcgag attacattac tcatagaaaa gcatcaggct atcgttccta
     8641 tcatgtggta gtagaatata cggttgatac catcaatgga gttaagacta ttttggcaga
     8701 aattcaaatt cgtactttgg ccatgaattt ctgggcaacg atagaacatt ctctcaacta
     8761 caagtaccaa ggggatttcc cagatgagat taagaagcga ctggaaatta cagctagaat
     8821 cgcccatcag ttggatgaag aaatgggtga aattcgtgat gatatccaag aagctcaggc
     8881 actttttgat cctttgagta gaaaattaaa tgacggtgta ggaaacagtg acgatacaga
     8941 tgaagaatac aggtaaacga attgatctga tagccaatag aaaaccgcag agtcaaaggg
     9001 ttttgtatga attgcgagat cgtttgaaga gaaatcagtt tatactcaat gataccaatc
     9061 cggatattgt catttccatt ggcggggatg gtatgctctt gtcggccttt cataagtacg
     9121 aaaatcagct tgagaaggtc cgctttatcg gtcttcacac tggacatttg ggcttctata
     9181 cagattatcg tgattttgag ttggacaagc tagtgactaa tttgcagcta gatactgggg
     9241 caagggtttc ttaccctgtt ctgaatgtga aggtctttct tgaaaatggt gaagttaaga
     9301 ttttcagagc actcaacgaa gccagcatcc gcaggtctga tcgaaccatg gtggcagata
     9361 ttgtaataaa tggtgttccc tttgaacgtt ttcgtggaga cgggctaaca gtttcgacac
     9421 cgactggtag tactgcctat aacaagtctc ttggcggtgc tgttttacac cctaccattg
     9481 aagctttgca attaacggaa attgccagcc ttaataatcg tgtctatcga acactgggct
     9541 cttccattat tgtgcctaag aaggataaga ttgaacttat tccaacaaga aacgattatc
     9601 atactatttc ggttgacaat agcgtttatt ctttccgtaa tattgagcgt attgagtatc
     9661 aaatcgccca tcataagatt cactttgtcg cgactcctag ccataccagt ttctggaacc
     9721 gtgttaagga tgcctttatc ggtgaggtgg atgaatgagg tttgaattta tcgcagatga
     9781 acatgtcaag gttaagacct tcttaaaaaa gcacgaggtt tctaagggat tgctggccaa
     9841 gattaagttt cgaggtggag ctattctggt caataatcaa ccgcaaaatg caacgtatct
     9901 attggacgtt ggagactacg ttaccattga cattcccgct gagaaaggct ttgaaacctt
     9961 ggaggctatt gagcttccat tagatattct ctatgaggat gaccactttc tagtcttgaa
    10021 taaaccctat ggagtggctt ctattcctag tgttaatcac tctaatacca ttgccaattt
    10081 tatcaagggt tactatgtca agcaaaatta tgaaaatcag caggttcaca ttgttaccag
    10141 actagatagg gacacttctg gcttgatgct ctttgccaag cacggttatg cccatgcacg
    10201 attagacaag cagttgcaga agaaatctat cgagaaacgc tactttgctt tggttaaggg
    10261 agatggacat ttggaaccag aaggggaaat tattgctccg attgcgcgtg atgaagattc
    10321 cattattacc agacgagtgg ctaaaggcgg aaagtatgcc catacttcat acaagattgt
    10381 agcttcttat ggaaatattc acttggtcta tattcacctg cacactggtc gaacccatca
    10441 aatccgagtc catttttctc atatcggttt tcctttgctg ggagatgatt tgtatggtgg
    10501 tagtctggaa gatggtattc aacgtcaggc tctgcattgc cattacctat ccttttatca
    10561 tccattttta gagcaagact tgcagttaga aagtcccttg ccggatgatt tcagtaacct
    10621 tattacccag ttatcaacta atactctata aaaactgtct cagagtataa ttattatctt
    10681 aaaggagaaa actcatggaa gtttttgaaa gtctcaaagc caaccttgtt ggtaaaaatg
    10741 ctcgtatcgt tctccctgaa ggggaagagc ctcgtattct tcaagcaaca aaacgcttag
    10801 taaaagaaac agaagtgatt cctgttttgc ttggaaatcc tgaaaaaatt aaaatttatc
    10861 ttgaaattga aggaatcatg gatggttatg aggtcatcga ccctcaacat tatcctcaat
    10921 ttgaagaaat ggtttctgcc ttggtggagc gtcgcaaggg caaaatgact gaagaagatg
    10981 tacgcaaggt tttggttgaa gatgtcaact actttggtgt gatgttggtt tacttgggct
    11041 tggttgatgg aatggtgtca ggagcgattc actcaacagc ttcaacagtt cgcccagctc
    11101 tacaaatcat caaaactcgt ccaaatgtaa ctcgtacttc aggagccttc ctcatggttc
    11161 gtggtacgga acgttaccta tttggagact gtgccattaa tatcaatcca gatgcagaag
    11221 ccttggctga aattgccatc aactcagcaa tcacagctaa gatgtttggc atcgaaccta
    11281 aaattgccat gttgagctat tctactaaag gttcagggtt tggtgaaagc gttgataagg
    11341 tcgttgaagc aactaaaatt gctcacgact tgcgtcctga ccttgaaatc gatggtgagt
    11401 tgcaatttga tgcggccttt gttcccgaaa ctgcagctct gaaagctccg ggaagtacag
    11461 tagctggtca agcaaatgtc ttcatcttcc caggtatcga ggcaggaaat atcggttaca
    11521 agatggctga acgcctgggt ggctttgcgg ctgtaggacc tgttttgcaa ggtttaaaca
    11581 agccagttaa tgatctttct cgtggatgta atgcagatga tgtttacaag ttgaccctca
    11641 tcacagcagc tcaagcagtt catcaatagt gaaaactata aagtgatata ctatgctata
    11701 ctgtagttat gaaactatgt acgaaaagca ctgccattaa ttcctgagaa ctaaattact
    11761 gattggtgtc aaaaaggaaa acttccaagc gatgatatcc tgtctataca cgacctatag
    11821 aaatctgtaa tatacatatc cgtaaaacga taaattccct ttttgatttt aaatgagtat
    11881 gaaaagagaa ttttttggct ctttgtcaac tgtagtgggt tgaagt
//
LOCUS       DBERCW010000053        11445 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.053, whole genome shotgun sequence.
ACCESSION   DBERCW010000053 DBERCW010000000
VERSION     DBERCW010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.053"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(141..992)
                     /gene="rgg"
                     /locus_tag="ACL72M_001908"
     CDS             complement(141..992)
                     /gene="rgg"
                     /locus_tag="ACL72M_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGS0716978.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNVAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFYTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            1116..1457
                     /locus_tag="ACL72M_001909"
     CDS             1116..1457
                     /locus_tag="ACL72M_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS0716979.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            1521..1685
                     /locus_tag="ACL72M_001910"
     CDS             1521..1685
                     /locus_tag="ACL72M_001910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0716980.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSPKHCFEVVDRTDEVS
                     NHTYGKATLT"
     gene            complement(1711..3414)
                     /gene="ilvD"
                     /locus_tag="ACL72M_001911"
     CDS             complement(1711..3414)
                     /gene="ilvD"
                     /locus_tag="ACL72M_001911"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGS0716981.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(3647..4579)
                     /locus_tag="ACL72M_001912"
     CDS             complement(3647..4579)
                     /locus_tag="ACL72M_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGS0716982.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(4576..5433)
                     /locus_tag="ACL72M_001913"
     CDS             complement(4576..5433)
                     /locus_tag="ACL72M_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS0716983.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(5437..6783)
                     /locus_tag="ACL72M_001914"
     CDS             complement(5437..6783)
                     /locus_tag="ACL72M_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0716984.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(6796..7080)
                     /locus_tag="ACL72M_001915"
     CDS             complement(6796..7080)
                     /locus_tag="ACL72M_001915"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0716985.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(7084..9114)
                     /locus_tag="ACL72M_001916"
     CDS             complement(7084..9114)
                     /locus_tag="ACL72M_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0716986.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            9305..10312
                     /locus_tag="ACL72M_001917"
     CDS             9305..10312
                     /locus_tag="ACL72M_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS0716987.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            10315..10515
                     /locus_tag="ACL72M_001918"
     CDS             10315..10515
                     /locus_tag="ACL72M_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0716988.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            10667..10849
                     /gene="rpmF"
                     /locus_tag="ACL72M_001919"
     CDS             10667..10849
                     /gene="rpmF"
                     /locus_tag="ACL72M_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGS0716989.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            10865..11014
                     /gene="rpmG"
                     /locus_tag="ACL72M_001920"
     CDS             10865..11014
                     /gene="rpmG"
                     /locus_tag="ACL72M_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0716990.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
BASE COUNT         3707 a         2410 c         1884 g         3444 t
ORIGIN      
        1 tagcacttat gaatttgcga aacgattctt ttgaatatat gcaacaaaca aaatgagcaa
       61 aaaaacgata gaacttttgt aatgacctga gagagggcaa cagttctatc gcttcaaatt
      121 ttttcttggt ttgcagatac tcaacattcg gtcgtatttc tatagtattc ggcagattta
      181 ttacagccaa gcatctcaaa aatacggaca gcatcctcca tctttttctg accttccttg
      241 actctacctt gcttgctatc aaggagacct tctgcccaca gataaacaat tcggaaatag
      301 gtctcatttt ccttgtagaa atgctcttcg ataacacgtt taaaataata ggcattggta
      361 aattcttcac actcaatact agctaaaaag ccattcaata gtatagtata aaaaaggttt
      421 cgattgccag acatttccat tagaaaatcg gatttacgta ccatttctcg tacatatcta
      481 gtaaaaagag aaacagataa aaatggagaa ctgactgaaa ataaattgag ttcatagatt
      541 ccccagatct cggtagaaaa caaataatca tgaaggactt ttccttcctc tgctgttaac
      601 tctacccttt catccatgct cttcatataa gacttgatca taatggcatt tagaatatgt
      661 ttctgtttgt tgtgagaatg ggcatgcttt tgatactccc tgcgatataa gtcctcaaga
      721 ggtgctacat tctttggttc caagacatct gtaatttctt ttctcaactc agaatctgta
      781 tcatactgga aacctctcgc cagaaagagg atctcctcca cactggcaga tatattttcc
      841 agagcaaata gaaacttttc caccgaaagc tcactctgac ctgtttcaaa acgggacaac
      901 atagacggcg aaaattgtcc tccggttgct tgtctcagtg agatatttct tgactctcgt
      961 aattgtctaa agacttttcc aatctgctcc atagacttcc ccttgattcc gtattttctt
     1021 cattttatca tatttttcag aaaattcatc aaaaacttgc caaattgtca gaattatgag
     1081 aaaatagagg atatttatca cgtggaggga ctgctatgag agacgatatc aaaatcaatg
     1141 accgtgcttt ggccttgcaa gaccaaatca tcgaaaaact agagaaagtt tttgatacag
     1201 atgtggaatt ggatgtttac aatctaggtc tgatttatga aatcaatctg gatgaaacgg
     1261 ggctctgcaa gattgtcatg accttcaccg atactgcctg tgattgcgcc gaaagcctgc
     1321 ctattgaaat cgtggcaggt ctgaaacaaa tcgagggtat caaagatatc aaggttgaag
     1381 ttacctggtc gcctgcttgg aaaatcacac gaatcagtcg ctatggccgt attgcccttg
     1441 gactaccacc tcgttaagca ggccaatcat ttttaaagat gaaaaaagca agccaaaaat
     1501 ggcttgcttt ttgatactca atgaaaatca aagggcaaac tagaaaacta gccgcaggtt
     1561 gctcaaaaca ctgttttgaa gttatggata gaactgacga agtcagccca aaacactgtt
     1621 ttgaggttgt ggatagaact gacgaagtca gtaaccatac ctacggcaag gcgacgttga
     1681 cgtgatttga agagattttc aagtatgagt ttatttttta cctgacttgt ccatattcca
     1741 gaagtctgtc acggctccgc gtgaagcaga tgatacgata tgggcatatt taccgaggac
     1801 accacggctg taaagtggtg gcaaggttgt ttctgccttg cgtttttcaa gttcttcttc
     1861 ggatacggcc atggaaattt ctttggtatc ttggtcaacc gtaacgatat cgccggtacg
     1921 gagataggca attggtccac catcctgagc ttcaggagcg atatgtccaa caaccagacc
     1981 ataagtacca ccagagaaac gtccgtccgt caagagggcc accttatctc cctgaccttt
     2041 accaacaatc attgaagaaa gtgacagcat ctcaggcata ccaggaccac ctttaggtcc
     2101 aacaaaacga acaacgacta catcgccatc aacgatttca tctgtcagaa cggcctgaat
     2161 cgcatcttct tctgagtcaa agaccttagc tggcccaacg tgacgacgca ctttaacacc
     2221 tgataccttg gcaactgcac cgtcaggagc aaggttcccg ttcaagatga taagcggacc
     2281 atccgcacgt tttggatttt caagtggcat gataactttt tggcctggag tcaagtctgc
     2341 aaagtcagcc aagttttcag ctacagtctt accagtacat gtgatgcgat ctccgtgaag
     2401 gaaaccattt gccaacaagt acttcataac cgcagggaca ccaccgactt cgtagaggtc
     2461 ttggaagaca tactgaccag atggtttcaa gtcggccaag tgaggcacac gttcttgaat
     2521 cgtattgaag tcctcaagtg acaagtcaac atttgcggca tgggcaatgg cgagcaagtg
     2581 aagagtggcg tttgtagaac caccgagagc catcgttaca gtaatagcat cttcaaaggc
     2641 ttcacgagtc aagatatctg atggtttgag accaagttcc aacatcttaa caacagcacg
     2701 tcctgctgct tcgatatctt ctttcttatc agctgattca gctgggtgag aggatgaccc
     2761 tggcaaactc atccctagaa cttcgatagc agttgccatg gtattagcag tatacatacc
     2821 accacaacca ccagggccag ggcaggcatt acattcaaga cgtttcacgt cctcagctgt
     2881 catgtcaccg tggttccatt ttccgatacc ttcaaagaca gaaaccaagt cgatatcttt
     2941 accatcaaga tttcccggtg caatagttcc accataggcg aaaatagctg ggatatccat
     3001 attagcaata gcaatcatag atccaggcat gttcttgtca cagccaccga tagcgacgaa
     3061 ggcatccacg ttgtgaccac tcatagccgc ctcgatggag tccgcgatga tgtcacgaga
     3121 tgttagagag aaacgcatac caggcgttcc catagcgatc ccgtccgcta cggtaatggt
     3181 tccaaactgt acaggccaag cgcctgcaga tttgacacct tctttagcca gtttcccgaa
     3241 atcatgcaag tgaatgttac atggtgtatt ttccgcccaa gtcgaaatca ctcccacaat
     3301 cgatgtttca aagtccttat ctgtcatacc agtcgcacga agcatagcac ggttaggtga
     3361 tttaaccatg ctgtcataga tgctactgcg gtgacgttta tctaattcag tcatcttatc
     3421 cctcccattt cagtttttac tattatagca caatttaaag gcaatgaaca gaataaaatt
     3481 cttgaatttt cagaaaattc tatacgcatg tgaaatattt aaaattaaaa acaacaaagc
     3541 ggattagtgc actttctgat gaccagaata tgctttttaa tccgctttct ttaaataacg
     3601 tactgtaatt tttacagaaa ttctttcaga taagtgtatt taacatctat cttgcattat
     3661 aaatttctag aaccttctct tttatattcg attcactcaa accatactca ttaagaagat
     3721 aatccatttt ccctacttga ccgaatcttt cttgaacacc catccgatga atttttgtta
     3781 ttccatcatc agagaataat tcacataaag cactgccaat tccacctatc tgattgtggt
     3841 tttctacagt aaatatagtt tttccactta acattgtttt tatctgttct ggtatcggtt
     3901 tgattctaaa taaatctatc acacttactg aataacctaa tttagacagt tcatctgcaa
     3961 ctcgaatact tggagcaacc attataccag aagcaacgat tacaagatct tcaccatgcc
     4021 ttaactcaat gtagccttta gaaaaatctt ctccaccttg atacacagga actggagctt
     4081 ttctaattgt tcgaatatat tttagtcctt ttaagtctaa tgtctggttc aatatttcac
     4141 gaaattggat atcatcagtt gcttcaaaaa tgatcgattt aggaattaaa cgtaacaatc
     4201 caatttcttc aaatggcata tgtgtcccac cattcatttc tgcagttact cctgcatctg
     4261 atccaatcac agtggcatcc aattgtgcgt atccaagaga aataaataat tgatcaaata
     4321 ctcttcgtga agcaaaagga ccaaatgtat gaagataagg tctaaacccc tgaatagaca
     4381 agcctgctgc aaggccgacc atttctgctt ccataatccc aacattcaca taacggtctc
     4441 caaagtcctt ttcaagatta tgagtagcca tcgaacttga caaatcggct tctaagacta
     4501 ctatatcaga atcactttga ttagcctcta aaaggaagtc tctatataca tgccgtaatt
     4561 ctttcgtgct tctcatcatt ctgtttcctc caattcctga cttaatcttt ctacaactga
     4621 ggttaacatt tgtctctcct ctacagtagg gcgaagatga tgattggatt tcatttcttc
     4681 cagctcttga accccttgac ctttaatagt atctaataca atgcacttag gtgatgaatt
     4741 atttgactgt tttaattgga caatcccttc ataaatttct ctaatatctg aacccttgac
     4801 cctaatggat tcaaatccaa atgctgaaaa tttttctacg aaatcacctg gattacaaat
     4861 atcctttgta aaaccatcta attgtttttt gttatcatca acaaatacaa ttaagttgga
     4921 taactgttga tgagaagcaa actgtatagc ctcccaacat tgtccctcat ttaactcacc
     4981 atctccaaca atagcataag tataaaaggg actctttctt attctctgac catatgcaag
     5041 tccagttgca acactaattc cttgtcctaa agagcccgtt gtcatatcta tgcctggcgt
     5101 tagatttcta tcaggatgag acggtaattt ggttccattt gtatttaaag aatataagaa
     5161 ttctttgtca aagaaaccat tcaaatagag tgtactgtat agagctggtc ctccatgacc
     5221 ttttgataat atgaaataat ctctatctcg tgctgcaaat atttctggag tcattggcat
     5281 tatttcacca taaagcactg ctaaaacttc tacgatagac agacttcctc cgtaatgtcc
     5341 gaatccaaga tgattcaatg ttctaagagt atttaatcgg atgttagtcg caaattttct
     5401 taacccatct tctctatttt tacttaaaat catcccttat tcctcctttg cagatggctt
     5461 tttaataaag gatactccaa acataactgc tagaataaga acaagaccaa tcacaatgcc
     5521 tgcttgtgag ccaaattgat ttaacattcc taaaataatt cctgatagac caaaatctgc
     5581 atctgagaaa gttgatcctt ggaaaccaag tcctcccaaa actggcatta aaaagactgg
     5641 aagaaaactg attaaaatac cttgtaaaaa tgctccaata gtggctccac gaacaccacc
     5701 agatgcattc ccaatgacac ctgcagtcgc tccacagaag aaatgaggca caacacctgg
     5761 taagataaca accgttcctg aagcaatcat aattgccata cttactaaac caccaataaa
     5821 actagagata aatccaatta gaactgcatt gggtgcataa gtataaacaa tcggacaatc
     5881 caaagcaggt tttgaattag gtacaagacg ctctgaaata cctttaaagg ctggaacaat
     5941 ttcgcccaaa ataaggcgaa cacctgctaa aataacaaat acccctgctg caaattgacc
     6001 tgctaattgt aaagcataaa ctagaccact tgtaccacta ctgatttctt tttctatata
     6061 ttctgaccct gcaaagatag ctacaataat gtaaataact gccatggata aagtaatact
     6121 aacagtacta tcacgtaaaa aagctaaact ctttggaaat ttaatgtcct ctgttgattt
     6181 tgatttgtca ccgataaggc taccagtaaa accactcaac caatatccca aagaactgaa
     6241 atgacctaaa gccaccttgt catttccagt taattgaacc atatattttt gaacaaatgc
     6301 tggggaaata ctcataataa taccgagtgc taatcctcct agtaagataa gaggcaagct
     6361 agtaaagcca gcaactgata aaatgaccgc aatcatacat gccatatata gagtgtggtg
     6421 ccctgttaaa aaaatatatt taaatcgagt aaaacgagcg attaagatat tgaacaccat
     6481 gcctgcaaac ataatcagtg cagtagctga gccatatgtt gttaaagcta cagctacaat
     6541 tgcttcatta ttcggcacaa cgccagataa atgaaaagca tgctcaaaca tggtaccaaa
     6601 tggatttaaa gaattttgta caattcctgc accaccagat acaactaaga aaccaacaaa
     6661 ggtcttaatt ccacctttaa taatatcagg taatttcttc ttctgaagaa ctaatcctaa
     6721 aattgcaatt aaagctacta aaatagctgg tgtactaaca atatccaata tgaacttcat
     6781 catgacgcta gcctcctata taagtccttt ttcttcacaa agtttagtaa ttaattctcg
     6841 tagttcatcc atatcaataa tactatttaa gatacgaaca tctccaagat gactagctga
     6901 atcagctaga tcacgaccaa caatccaaat atcagctgca tttggatctg ctccacctaa
     6961 atcataatgt tcaacttcta catctgaaac attcaaatca ctcaatacag attcaatatt
     7021 catctgtacc ataaaacttg aacctaatcc tgaaccacaa gctgtaccaa tttttaacat
     7081 tatctaatcc tcctgtttaa ttatcatttt aatgtcatca tagttttttg atgatattaa
     7141 agtttgaaca tgatttttat ctcttaaaat tgttgttaaa tgtgacaaag cctttaaatg
     7201 actctcatta tcaatggctg caatacaaat caacaatctt acctcttgtt ctggattatc
     7261 caataaataa atcggttctt ccaaaactaa cattgacatt cctatttcat tcacaccttc
     7321 atctggccga gcgtgaggaa ttgctactcc cttccctaaa ttaataaaag gcccaaactc
     7381 ttctactttt tgaatcattg cctcagggta gttctcagtt atcttatctt gatccaaaag
     7441 cggtttagct gctaaacgaa tcgcctcctt ccatcctaat ttttgcgaac taacctgata
     7501 ggtttctttg gtaatgagtt gttctagcac tggtacaatt tcctttctat catttttttg
     7561 gtaaagataa ttctttaacg ccaatcttaa ttccaattct tgtgtaataa ttccatatct
     7621 tttgacaata ttcagaattt gttcaatctc aaaatcccca tactctaaat tcggaaaatc
     7681 ttttaacact agttctacta gttgtattgc ttgctcttca gtcatcataa ccgaaactag
     7741 ataatttggc ttttctgtct ccacctttat ggtagaaaaa accatatcat agtcactact
     7801 agctttcacc tgtaaatcat caatctttga ggttcctata aactcaattt gaggaaataa
     7861 tgctaataga ttctctttta acatcaatga agaactaaca ccattaggac aaatgattgc
     7921 tgctttatac catttttgag gcaaagtatc tgctttcttt aaataacctc cgaaatggat
     7981 aacaaaatat gctgtttcac tatcaggtat gggattgtca atagcgtcca tcaagggcat
     8041 caaagaatct ttgactaatt caaataaatc aggataatat tctttaacat gcaatacata
     8101 ttcatttgaa ctaggtaggc cgaactttaa tctatagtaa gccggtataa ggtggcggcg
     8161 aagattttct ctcaatcctt ccctttgttt aaaatgtaac aaagaaatat cttccattct
     8221 acttataata gcctctgtta attgattaaa gtaaaccgga gcaacatcta cttcaccttc
     8281 aaagcaactt gataataaaa ctgtgatata gcgataatca tcctcagaaa acaccgtatc
     8341 tataattccc aaatcaacca ctgtatccaa taaaatagtg gttatatctt gaataacagg
     8401 agatactaat gtctctgaaa gacatactct ttcaacatcc ctttgatacc tacacagaat
     8461 gaatactaaa ccgaaaaggc aaacttttaa ttgattaaca ataggtacta gttgtagctt
     8521 ctcataataa tctttaacta cctgatttat caaatcataa gttaatgaat acccccaact
     8581 ggataaaaca taatccaaac cccaaatccc tatggaggat tccagcaact cactaaccat
     8641 ttgaaaagct aagcggtgct tattccactc tgaaccgtgt aaagtataac cttttgctct
     8701 actgtaccct agctccaaat cattatctaa cataatcttt cttaatgatt gaatatcaga
     8761 taaggttgta ttcttactta ctttcaaaaa gtcttggtaa tgattattcg atataaaatc
     8821 taatcggcaa aaagtgtaaa gatagattaa agctaagcga gtcgactttg gtaaaaccaa
     8881 ttcatccgac ttaataatat ctgtcaaaga ctgcttcgta cgatttgata aactatagcg
     8941 accttgtttt ttatccagca ctatcccttt attagctaga taaggcacta aataatctat
     9001 tccttctttg acttccttta taggtaagct caccttaaca gataattcat ataatgatag
     9061 ctcacaatga tccatcaaag tcatcaaaat aactagtgct ctataatcaa acatttctct
     9121 tcctttctaa ctacaattat agtgtaaaaa ttataagaat aaaagagtat ttgagcacaa
     9181 tataatctca ccttttaaaa gaaattattg ggctgaaagt ttttagtgat tattttcaac
     9241 tttctattga cttttaaaaa caaagtgata tcatttagat atcaaataat gggaggtcat
     9301 tcttatgact gaaaaactaa tcaattcaaa accaaatggt gtattcgcat tgattctcat
     9361 tgagttgaca atcgtacttg gtgtctttat atttataatg ggtgttggtt cggaaaacat
     9421 ttttggaatt attatcggac ctttactaat cgtaattgca ggtctagctc atgctggttt
     9481 aaaagttgtc aaacctcagg aagctctggt tctgacactc tttggtaact atacaggtac
     9541 catcaaagaa cctggttttt actttgtcaa tcccttcagc gtagcagtca accctgcaaa
     9601 ccacactcga cttggacaaa gtggtgatgt tagcacaaaa tctccttttt taggagctaa
     9661 atcatcaaat gacaatgatg taaatcttga aattggcaag aaacagattt ccctcaaagt
     9721 catgaccttg agcaattctc gtcaaaaaat caatgattgc ttaggaaacc ctgtagaaat
     9781 cggtatcgcg gtaacttgga gagttgtcga taccgctaag gcagtcttca acgttgataa
     9841 ctacaaagaa tatctttcat tgcaatgtga tagcgccctc cgtaatattg tccgcatcta
     9901 tccttacgat gtgtctccta atgtggatac tacgggtgac gggcaagcag atgaaggtag
     9961 tctccgtggc tctagcgaaa ttgttgctaa ccgtattcgt gaagaaatcc aaagtcgtgt
    10021 tgaggatgct ggcttggaaa tccttgaagc acgtatcact tacctagctt atgctccaga
    10081 aattgctgcc gttatgcttc aacgccaaca agcatctgcc attattgatg cacggaagat
    10141 gattgtagat ggtgctgtag gaatggttga aatggcacta gaacggctca atgaagggga
    10201 attggtagaa cttgacgaag aacgaaaagc tgccatggtt tcaaatctcc ttgtcgttct
    10261 ttgtggcaat catgatgcac aaccaattgt caacacagga agtctttact aaagatggct
    10321 gaagctaaaa aaaagcagat cccccttcga ctctcaacaa agttatacgc tgcactcgca
    10381 tcatgggcag aagacgactt tcgttcagtc aatgggcaaa tcgaatatct cctcacagag
    10441 tgtgtcaagc aacggaagaa agacggaaaa tacgtatcag aaaccattga cgaaccattt
    10501 gagattgata tttaacatct tctcctgtct gacaagtcgg acaggagaat tttttcatct
    10561 ttttttgtca agtaacttta ctttacaaaa aaaatgtgtt atcctagtat ggttgatgaa
    10621 aatcagtaga ttgaatcgaa tataaatacc taaaggagaa atcaaaatgg cagtacctgc
    10681 acgtcgcact tcaaaagcga agaaaaacaa acgtcgtaca cactacaaag taacagctcc
    10741 atctgtaaac tttgacgaaa ctactggaga ttactcacgt tctcaccgtg tatcacttaa
    10801 aggatactac aaaggacgta aaatcgctaa agctgcatca gctgaataat agaagggaga
    10861 taccatgcgc gtaaatatta cacttgaaca caaagaatct ggtgaacgct tgtaccttac
    10921 ttctaaaaac aaacgtaaca ctccagaccg ccttcaattg aagaaatact caccaaaact
    10981 tcgcaaacac gttgtgttta cagaagttaa gtaagcattc aatacgaatc aatacagaag
    11041 aaaaacgctt gatcagcgtt ttttcttttt gttaatttca ctatattgca agggaaatca
    11101 ttcgaatgac tacatttttc actacctttt ttgaaataag aatacggatt cggacgatta
    11161 aaagtaagag aaactcaaat gtaagttggg gttccttttt tgtatatttt tcaaataacg
    11221 cctctacact atttgtagca aattcaccaa ctacagttgt atcttagtta aaataagtta
    11281 gaatatgtaa gtgagtacca gatataccaa gacatcgtca ccatctaagg tatattcaaa
    11341 atacaaaagt tgaccaacta gatttctgaa tatccttata tatccattct taaaattggt
    11401 ttaaatagcg tagtctttta aactagtttt gagaatccaa aaaat
//
LOCUS       DBERCW010000054        10754 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.054, whole genome shotgun sequence.
ACCESSION   DBERCW010000054 DBERCW010000000
VERSION     DBERCW010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.054"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(99..1313)
                     /locus_tag="ACL72M_001921"
     CDS             complement(99..1313)
                     /locus_tag="ACL72M_001921"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0716991.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1469..1763)
                     /locus_tag="ACL72M_001922"
                     /pseudo
     CDS             complement(1469..1763)
                     /locus_tag="ACL72M_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1925..2377
                     /locus_tag="ACL72M_001923"
     CDS             1925..2377
                     /locus_tag="ACL72M_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGS0716992.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2412..3800)
                     /locus_tag="ACL72M_001924"
     CDS             complement(2412..3800)
                     /locus_tag="ACL72M_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0716993.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3866..4828
                     /locus_tag="ACL72M_001925"
     CDS             3866..4828
                     /locus_tag="ACL72M_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGS0716994.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(5034..6044)
                     /gene="ccpA"
                     /locus_tag="ACL72M_001926"
     CDS             complement(5034..6044)
                     /gene="ccpA"
                     /locus_tag="ACL72M_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGS0716995.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6468..7067)
                     /locus_tag="ACL72M_001927"
     CDS             complement(6468..7067)
                     /locus_tag="ACL72M_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0716996.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLAFQADVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7068..8165)
                     /locus_tag="ACL72M_001928"
     CDS             complement(7068..8165)
                     /locus_tag="ACL72M_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0716997.1"
                     /translation="MLERLKSIDYMYWASLIFMIFPILPVVTGEIPSWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERAEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVSPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8165..8902)
                     /locus_tag="ACL72M_001929"
     CDS             complement(8165..8902)
                     /locus_tag="ACL72M_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0716998.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHTPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHFVRGVDMPLGSWIGAAFLLIVGSVAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYILVFSAVLFGLTIYLQGHKENA"
     gene            complement(8904..9788)
                     /locus_tag="ACL72M_001930"
     CDS             complement(8904..9788)
                     /locus_tag="ACL72M_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0716999.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(9775..9969)
                     /locus_tag="ACL72M_001931"
     CDS             complement(9775..9969)
                     /locus_tag="ACL72M_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717000.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(9966..10172)
                     /locus_tag="ACL72M_001932"
                     /pseudo
     CDS             complement(9966..10172)
                     /locus_tag="ACL72M_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3285 a         2453 c         1936 g         3080 t
ORIGIN      
        1 ttggattaac aactacccta aaaaatgctt ggactacaag tcgccaagtg aatttctttt
       61 gggtggctaa cttcaacttg aaatttggga tgcaagccct atctacgata ctgtttcaag
      121 aaacgagtca tcttttcttg gatttgggct aactcatcaa cacgaggaag gtaaacgata
      181 cggaagtggt ctggttcctg ccagttaaag cctcgaccat gaaccaagag aaccttttcc
      241 tgcttcaaga aatcaaggac aaactgctca tcatcatcga tacggtacat attgcggtcg
      301 atttttggga agatatagag ccccgccttg ggtttaacgg cagacaaacc tggaatatct
      361 tgaatggcat tatagatgaa atttctttgc tcgtagattc gtccaccagg aagaagcaat
      421 tcatcgactg attggtgacc ccccaaggaa gtttgtacga cttgttgggc caaaacgtta
      481 gagcaaaggc gcatattgga cagcatattg agcccttcga tatagccctt aacatgagtc
      541 ttagggccag acaagaccat ccaacccaca cggaaacctg ctatgcggtg ggattttgac
      601 agaccattca tgctgacaca gaagacatct ggtgccaagc tcgccacagg cgtatgcaca
      661 tgtccgtcca ttaccatgcg gtcatagatt tcatccgcaa agataatcaa atcgttttga
      721 cgggcaatct caataatctc cagcaagagt tccttaggat aaagggctcc agttgggtta
      781 tttggattga taaggacaat tgccttggta ttggaagtga tttttgactt gatatcgtca
      841 atatctgggt accattccac agcttcatca cagatatagt gaacggcatt tcctccagct
      901 aggctgacag ccgccgtcca tagaggatag tctggcattg gcactaagac ctcatcccca
      961 ttgtccaaaa gcccctgcat ggacatgaca atcaactcac tgacaccatt tccaaggtaa
     1021 atatcatcaa tatctacgtt tgggaatttc ttcagctggc aatactgcat gatggcctta
     1081 cgggctgaga aaatcccttt ggagtcagaa tagccttcac tatcacgcgc attcataatc
     1141 aagtcatgaa tgacctcgtc tggcgctgta aagccaaatt ctgctggatt tcctgtattc
     1201 agacgtaaaa tcttttctcc attcgctcgc atccgcatgg cttcttccaa tacaggacca
     1261 cggatatcat aagcaacatg ctctaactta ctagacttgt tatattcttt catcttgttt
     1321 cctcaattca tcaggatagt aacattatac cactagaaag agaatgcgac aagtttactg
     1381 aaatgtgtta ctagtttcgt atagaagaaa aaccttgcta aaggcgaggt taagaacgta
     1441 gagatagcag gtattttgca aagacacatc acataccaaa agataaacct agaaaaaagc
     1501 aagcctagaa aggagtcata aagaagatta aacatgagga aaagccccca tatcatcaag
     1561 taatcccaac gcccacttcg ttttgcaact agaaataaga ttagatggta gagtacatga
     1621 aaaactaaaa atccaataaa acttggataa agaagcggta ccagactctc taattgacag
     1681 atcatgatca cttctaccaa gactgaaact aggataattc cataataaag gaaatttgat
     1741 ttttgaaaag agtttttcat cattctccct tccttcactt ctttcctgct atcctttctt
     1801 ttattttatc atatatttat atagagttta agccctaata ttcttttgaa aaatactttt
     1861 tttgctttac ttctatagtg aaaaggttta caattatagt aagaaaattt caggaggttt
     1921 cattatggca caacgttacc aaaatatcat ggtcgcaatc gatggttcta aggaagcgga
     1981 cttggctttt gtcaagggag ttcattctgc tctacgaaac gacgctaaac tcaccatcgc
     2041 acatgtcatt gacacacgcg ctctccaaag cgtatccacc tttgatgctg aagtttacga
     2101 agaactccaa gtcgacgctg aaagtctgat gaaagagtac gaaaaacgtg ctaaagatgc
     2161 tggggtagca gatgttcata tcgtcattga aatgggaaat ccaaagaccc tgctagcacg
     2221 tactattcca gatgccgagg aagtggacct catcctcgtt ggcgcaactg gtctcaacgc
     2281 ctttgaacgc ctcttggtcg gctcttcatc tgaatacata ctccgccatg ctaaggtcga
     2341 tttgctggtt gtgagagaac aagaaaaaac cttataatca caaagaaaag gagcccctag
     2401 ctcctttttg tttacgattt atttctctct ttatggcgtt cgtaagcctt gagctggcgc
     2461 tgcagttcct ttttaatagc aggttctgga gcatattttt cttcccaatt atctggtttt
     2521 aagattttat gggtcactgg atcaaaatga gccttgccat ctggaaaaat tttccccata
     2581 ttggcctgat ggacaatatc aaaaatacgt tctgggtcca cccccatcaa gacaaaactg
     2641 ccgtaggtga agtaaagcgt gtcaatcaag gcatccactt gccctatcaa atcttgctga
     2701 gcaggtgtct tcttggctac tttacctgct gccttatcaa gggcctgatg aagttgcgat
     2761 acagcttgac caaaatcttc ttcagaagga ctggctgatc gaacaaactc caccaattct
     2821 tctattttaa aaccagccct atgggttgca ccctctaaat cccaagctcg aggttcttct
     2881 tgggttcgtt catccatcat gtggtggaag gtcttgacct tattgaaatg atagtcacgg
     2941 ctgacaaaaa ctttttctga agacaaaaca ccaaaatgtt ccaaggcctt gtggatccca
     3001 tcttgttgat tgctagtggt aatgtgcttg gcagcttcct tgacactgct actaccattt
     3061 cccatagcga ccgacatacc gacgccagcc agcatttcaa ggtcattatc tgagtcacca
     3121 aaagccatga cttggttgag gtcaaagcca tattctttcc caactcggcg aatgccttct
     3181 aatttagaat ttccctgatt gatgacatcc gatgcaaaag gattgctacg tgtcaatttc
     3241 aagtcttcaa aatcagctgc cgccttctca gattcttctg gtgtcatcag catcaaaact
     3301 tggtaaatag gttgattcat caggtgaagc aggtcctctt ccttttgggg aacaaccttg
     3361 ctgaccatgc gattaaaaga ctgactcacc gtccgagtta aaacagaggg aacgaagcga
     3421 ctaattcgtt gggaaaaaga acccagacca aaggacatga ttttagaacc caacatggca
     3481 tccttggtcc ctaaggcaat ctccgtgccc tcttttttag catagctaat tagatggcgc
     3541 aaatgtaact tggaaatagg gctcgtgaac aagactctgt ctttactaaa gatatactgg
     3601 ccattatagg ttaccgcaaa atccagatcc aaatcgtcca tcaattcctt aacaaaaaaa
     3661 ggtcctcgcc ctgtcgctac gccaactagt accccttgtt ctttgacaat cttaatcgca
     3721 tccttagtgg atttcaaaac actcttgcga ttgttgacca aggttccatc gatatcaaaa
     3781 aaaacagctt tgacttccat cctatcccaa tctccccttt tgtgatacaa tgattatacc
     3841 acatttcaga aagagtgagt aaatcatgcc taagaaaatc cttgttttac atacgggtgg
     3901 aactatttcc atgcaggccg atgcttctgg cgctgttgtg acgagttcag ataatcccat
     3961 gaaccatgtg tccaacccac ttgaaggaat ccaagtccac gccttggact tttttaacct
     4021 tccaagtccc catatcaaac ccaaacatat gctggtcctc taccagaaaa ttaaagagga
     4081 agcagataac tacgatggag tggtgatcac acacggaacc gatactttag aggaaacagc
     4141 ctatttcctt gataccatgg aagttcccca tatgcctatc gttctaacag gagccatgcg
     4201 tagctccaat gaactcggta gtgatggtgt ttataattac ctaagtgctt tacgagtggc
     4261 cagcgatgac agggctgctg acaaaggagt tttggtcgtt atgaacgatg aaatccacgc
     4321 tgccaagtat gtcaccaaaa cacatacgac taatgtcagc accttccaga ctccaacaca
     4381 tggccccctt ggtctcatca tgaaacagga aatcctctac ttcaaaacag ctgaacctcg
     4441 tgttcgcttt gaccttgatc acatacaagg tttagtccct atcatctcgg cttatgctgg
     4501 tatgacagat gagctgattg atatgctgga tttagaacac ttggacggtt tgattatcca
     4561 agccttcgga gctggtaata ttcccaaaga aacggctcaa aaattagaaa gccttctgca
     4621 aaaaggaatt ccagtcgctc tggtatcacg atgctttaac ggtattgccg agcctgttta
     4681 tgcctaccag ggtgggggcg tacagttgca aaaagcaggc gttttctttg ttaaagaact
     4741 caacgcccaa aaagctcgct tgaaactcct catcgccctc aatgccggac taacaggaca
     4801 ggctttgaaa gactatatgg aaggctaata ctcttcgaaa atctctgcaa accacgtcac
     4861 gtcgccttac cgtatgtatg gttactgact tcgtcagttt catctacaac ctcaaaacag
     4921 tgtgttgcgc agcctttaac cagccgccta gtccgctcta tggtattcat taagtcaaca
     4981 tctcttgttt aagagcacaa aatcaggaaa tcttctcgat tccctgattt tttctattta
     5041 cgttttcgtg ttgagctacg ttctgtcaaa ccatgaggta agagaacttc acgttcttcc
     5101 aactcttcct tatgcataat cttggtcaac atacgcatac taatggcacc aaggtcataa
     5161 agaggttggg caatcgttgt caagtttgga cgggtaaagc gtgagatttg tgaatcatca
     5221 ctagtaataa tttcaaaatc ttctggcaca gaaacaccct tatcagccaa accgttcaag
     5281 actcctgctg ccaactcatc acctgtcaca actgctgcag ttgcatttga tgaaatcaaa
     5341 cgctctgcta aggcgtaacc atcatcatag ctatatttag attcaaatac caaaccctca
     5401 ctataagtga ttcctgcttt tttcaaggtt tccttgtagc caactaaacg aaccttacca
     5461 ttgatgtcat ccactagcgg accgctaacg aaagcaatac gctcattttc tttaacaagg
     5521 taactcactg catcaattgt tgcttgctta tagtcaatat tgacacttgg caactggtgc
     5581 tcaacatcga cagttcctgc gagaacaatc ggagtacgtg aacgcgaaaa ttctgagcga
     5641 attttatctg tcaagtgata acccatatag ataatgccat ctacctgctt tgaaaagagg
     5701 gtattgacaa cagaaacttc tttctcgtta tcttcatcgc tattagctag gacaatattg
     5761 tacttgtaca tttctgcaat atcatcaatc cccttagcca aactcgaaaa ataaccattg
     5821 gtaatatttg gaatcacgac accgacagtg gttgtctttt tacttgcaag accacgcgca
     5881 actgcatttg gacgataatc caaacgatca attacctcta gcactttttt acgggtattc
     5941 tcttttacat ttttattgcc attgaccaca cggctgaccg tcgccatgga aacacctgct
     6001 tcacgagcga catcataaat ggttactgta tcatctgcat tcattccttt tcctgtcctt
     6061 tctatctcac acattctttt acaagtagag gtgctgattg aagctctata tctacttaca
     6121 aaagtgaaga tgtgaaaatt tcgttttcat atttctactt attccattct atcactaatt
     6181 gtaaacactt tcaagtgttt tttgaagatt gattgaaaaa atttcataga aaacctaggt
     6241 ttagctcctt gctaccacct tagactaaac aaaaaggagg aaactaagcc ctcctaaagt
     6301 tatagtaaaa tgaaataaga acaggataaa tcgatcagga cagtcaaatc gatttctaac
     6361 aatgttttag aagtagaggt gtactattct agtttcaatc tactataggt attgttccat
     6421 tcactaccgt caattttagc acatagtctt cataaaatat tatatcatca taaccaacca
     6481 gattcttttg cgatattagc tgcctctgtt cgattaccag catccagttt tgaaagaata
     6541 ttggtgacat agtttcgaat agttccgttt gagaggtaaa gctgatctgc gatttcttgg
     6601 ttggataagc cccgggcgat tccctttaag acagcaatct cttgttctgt caacggattg
     6661 ggacgggtca tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg
     6721 gtgtgcaagg tttgcatgag gtctgcaatg cttcgttcct ttaatacata agcatctact
     6781 ccagccttga ccgcacgttc aaaataccct gggcgcttga aggtcgtcac tacaaccacc
     6841 tttgtttcga gcttttctgc tcgtatccac tccaagactt cgagtcctgt cttaacaggc
     6901 atttctacgt caaggatggc gatatctaca gactcctttt ctaatagttg aattgcttct
     6961 tgaccattct tggcttgtaa gacagactct acatctgctt gaaaggcaag caactggcac
     7021 atggcatctc gcaacatact ttgatcttct gcgactaata ctttcatcta ctttctctcc
     7081 ttataaggta gtcgaacttg cacttccgtt ggatgtttct gactgattac acttacttct
     7141 cctgaaaatg gagaaacacg atctcggact gtatggagct catctccttt tagaaaagca
     7201 aagccgcagc catcatcact tactgttaaa atgagttctt tctctgcccg ttctaatttc
     7261 aggtaggcct tcgacgcttt ggcatgtttg ataatattgg tcaccaactc aagcaaaatc
     7321 atggaagccg ttgactccaa ttcttgagta agactagcag tatctagttg gttatccgtt
     7381 tccacctcaa ttccagcaat ttctaacatc tttttcacag tctctagttc ggatgtcaaa
     7441 gttctagact taagattttc cacaatggtt cgcacttcat tcatggaatc cttactgatc
     7501 tggtgaattt cttttaattc cttttccacc tgtggataag cctccatctg aaataactgc
     7561 aaggctaaat ctgtcttgac actcaacata gcaaaggtat gtcccaagct atcatgcaaa
     7621 tcctgaccga tacgactgcg ttcattttca gcaagcaata gatttatctg ggcattttgc
     7681 ttgacctgag cttctttcaa atcctccaca atacgaatcc gaaccaagcc aaaagtcatt
     7741 aaatcgacaa aagcaagaat tacaagtaga tagaatagaa actcaacttc gattctctga
     7801 aaaatcaaca gttggcccac aacaaggact tgagcaagaa gaaaagtcca gacatgtaaa
     7861 gactttaaac cacctacgct gaaatgataa cttaagagat tggataggaa aaagaaaaac
     7921 cagatataat taacagcaac aaaggcagta ttcccaacta cataagtcag catgaggccc
     7981 caatatagcc aagataggcg ctggctctta gttgttaaaa cacccaaata cgccactaca
     8041 aatagaatat caatcaataa atgccagcta ggaatctccc cagtcactac aggtaggatg
     8101 gggaaaatca taaaaattaa actggcccaa tacatatagt ctatgctttt tagtctttca
     8161 agcattaagc attctcctta tgaccttgaa gataaatggt caaaccaaac aaaactgctg
     8221 aaaaaacaag tatataaact gtggctgata gattgatgcc accctcgttt aagaaggttt
     8281 tgagcaactc catcaactga taagttggta ggcacttccc gattgcttgc atccagtctg
     8341 gaaataaaga gatgggcatc cagagtccgc ctaaaacagc caagcctaga tagagaagat
     8401 tgcccacgac agacatcaac tgactagaag gcaagagtgt caaggtcaag ccaagcgcta
     8461 caaaggcaac acttcctact attagcaaga acgcagcccc aatccagctt cctagaggca
     8521 tatccacacc tcttacaaaa tgcccaactg agaaaacaac cagaattgat accaaataat
     8581 caaccatcat acttgttatc tttgatagat aatattctac catatttaca ggggtatggc
     8641 gcaatgtttt ctgccagttg ttgattttat cagtatgtaa gacagctggg aatgaaaaca
     8701 tagctgtcga catcatggaa aaggctgtca tggagatgag gtaatcacgc ataaaattcg
     8761 cgagttcacc tggtgtgtcc tgatagatac cagaaaaaaa taaatagaaa gccgtcggca
     8821 tccctaccga caatagataa tagattaatt gtcgtttggt caataaaaat tctatcttac
     8881 taagtgctat ccatcgtttc atcttagtta tctccctttt gtgtttcttc aaagattgta
     8941 ttcaacaaac tacgattatt aacttcgatt tcttgcatcc tacatcctgc ttgggctaat
     9001 agttcccaga aagcatctgc ttctcgagtg actacttgta gagcatcctg tttttgtgac
     9061 cagttttcaa ccaagttaga ctgctcaatg acttccttgt atgccagagg aaggataaaa
     9121 tgcttttcaa ttccctcact acgcatagct agaggcgtcg tatcacgaat caactctccc
     9181 ttatttaaaa ccaaaatccg gtcagccgta tgctctacct cttcaatata atgagacgaa
     9241 tagagaatcg tgactccttg cgcttttagg tcccgaacga tttcccaaaa gcgttgacga
     9301 gttgaagtat ccatggcagc agttggttca tctaaaaaga caagctttgg tcgcccaatc
     9361 aaggtcaaga caaaagagaa gagacgcttt tgcccgcctg acaatttttc tgcgaattgc
     9421 tctttttgtt gctggtcaaa ctgcaatagt tgatcgattt cctgatcgct caaggaattt
     9481 ggatagatac gttgaaagaa agcaatcaac tctttgacct ttaatttctg aacgatgaca
     9541 ttttcttgag gcagataacc tctaatatag tctaactgag aactcgtcac tgacaagcct
     9601 tggatggata cttgaccgct tgtgaccagt ttatctccaa gcagacagtc caagagtgtg
     9661 gtcttcccag caccattggg cccaatcaag gcgacgcatt caccttcagc tacctcaaag
     9721 gaaataccct tcaaaatagc cttgcccttg atgtttttat ttaggctttc taccttaatc
     9781 atattcatga tattctcctt tcaaccactc cattctcata aggaaaacga cgaaaatcat
     9841 aaatccaaac cccaaagcac cacgaatgaa ttggcgaagc aaggtttggt caaaccaacc
     9901 tgtaaacatt tccactaacc ataccaagag tgacaggccg ataaagaaat agatgatccc
     9961 tctcttcatt cctcaaactc ctttttcaca tctccgacta atttcaaacc ttctctaaca
    10021 agccaagaca tcattccaaa gccagcaaag agctcccaag gaaaatgata gaaactctca
    10081 tccaatcccg aaaacatgag ttaggtcata actcctgcta ctactaaact cactgcgata
    10141 atcattttat ttctcatctc ttcttcctcc atttcatact acaattatag tcttttgaaa
    10201 tcagaggaga cagaagcttc tgtcactaga aaatatgaca aatgtcataa aaaattctat
    10261 tcaaaacaag caagatacac tatacaataa aacacaatca gaaaaatcta aggcaacttc
    10321 ctcaaaagag atatcaaacc caattcacac cataatgtaa actaatactt atttaaaatc
    10381 aaaaagagta gaaattttta tcagacaaac acatatatag tgtattgaat ctataacagt
    10441 agggcttaaa tactaacata tttctataaa ttaatttaac tttcctgata gagctgttca
    10501 tatcttattt caattctcta tattatacgt tgaacaaaac ccttctattg ctttcttaaa
    10561 aatttataag agttataaaa tctgttaaat ttcaatgtgt atacctaaac tacggtattt
    10621 attgaaaaga ctggggacaa aaagtatacg ctgccaaaat gaattactga aaatcaaaaa
    10681 agagagaacc aaactgattc cctcttaatg tatataatat ctagttttaa aaatacacac
    10741 tcacatatct ctgt
//
LOCUS       DBERCW010000055        10559 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.055, whole genome shotgun sequence.
ACCESSION   DBERCW010000055 DBERCW010000000
VERSION     DBERCW010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10559
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.055"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            122..277
                     /locus_tag="ACL72M_001933"
                     /pseudo
     CDS             122..277
                     /locus_tag="ACL72M_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="ACL72M_001934"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="ACL72M_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGS0717001.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="ACL72M_001935"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="ACL72M_001935"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGS0717002.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKANFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7614..8792
                     /locus_tag="ACL72M_001936"
     CDS             7614..8792
                     /locus_tag="ACL72M_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717003.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9001..>10559
                     /gene="iga"
                     /locus_tag="ACL72M_001937"
     CDS             9001..>10559
                     /gene="iga"
                     /locus_tag="ACL72M_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HGS0717004.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEAPKEYTG"
BASE COUNT         3372 a         2134 c         2239 g         2814 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct accagtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cggacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 atcatgagat gaccaaatcc cagatgagtt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaaggtc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc accttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcctgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagtat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga tttgtatact gacctcagtc
     1681 agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat ggcttgccag
     1741 cctttcagca aatcttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttctg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggcaaaacc taaaccaagc gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatctgca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggaa gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaaattgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggt
     3721 ttgaaaaaat aagagaggag ttaaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 acaaatcgaa gctatctaca cttctggtca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg cagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgatctca aacaacactt
     4081 gggtcgccag ttggcagacc tacccaacgc tgccatcgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agagctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc ggcagcaagt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctctggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagttcg atagtcaggc
     4621 ttatcaggca gtacttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgtgctct
     4681 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttactaaac taggacaatt atcagaccag atagcgattc tcgactatca
     4801 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4861 ttttgtagag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatccccaa gaaggcaagc tcattctcct caaggcaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac aagcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg aattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttg gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5821 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 aacccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaagtca agcaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgttttgag ctgattgcgg
     7561 ctagctttct agtttgctct ttgattttta ttgagtatta gaaaggagac ctcatgacac
     7621 ttccagttag aaaatccctg cacgatgcag ttttacaggc ttcgaaagcg gatacttggg
     7681 aacaagctac caaggaatgg aatgaagttt ccttgatttt taacggtatc ggccgtagca
     7741 attgtgtctg tggaaatgcc atcaaatacg cttatgaact ctttaacggt gtcacaggcc
     7801 aacgcctctt tccaattggt agcgactgtg ttcgtcattt tcatcgattg tcccttgacc
     7861 agcaattgga agaggaagaa aaactgctca gaaaggttga aaatctaacc agaaaagctc
     7921 agaaaaagga aaaaatcaag gtcaataaaa gtgactttga cgagcgactt ctaaaatggc
     7981 tctgggaaaa aggtgttttc aaacccaatc gtggcaatca atttgcgcct gagagagact
     8041 accagctttt cctagaagtc tttcagggag gaagttggac caaggcggaa ccaaagaaaa
     8101 aggctcggat ggaagaagtc cttgaaaagt gtatcaaacc ctttttactt gggaaatcgg
     8161 atgaccaact ctaccttgtc aagctaggca aggagaaaat tgactacgaa caagaactcc
     8221 gtatccaggc agagaaagaa cgcaagaaga gggataaaat cgccaagcaa tatgcagaca
     8281 atctggttct agccatggga cccgcagagc gtgcttatca agattacttt ggctttacag
     8341 agaccctgac tcaagaagaa cgcaagtggg aaaaaattct ttttggtaaa aatagagcag
     8401 aacgggctat caaggccaaa caataccaaa aagagctgga aaaagaccaa cgaattgcca
     8461 gtcaggatcc aattgaaaga aaacagaagc agacttggct cctcaattcc tattttcgtg
     8521 agcttcctga agaaaaagct cgattttcta ggctcttatt agaatatcga aaaagtggtg
     8581 aagtaccctt ttcaactgaa tacctgtccg atcatctcat cgactttttc tataaaatga
     8641 aagcctttga atttgaaatc gcaccagaac aagtccgaga ttttctaaaa aaaagcctgc
     8701 aggaagacca tcgctcatca gcacaaggaa gctggataga aggaattctc ctcaactgcc
     8761 tcaaaccatt tttagaacga ttagtgatat gagtaacacc taccgtgtaa atttcatggt
     8821 aggtgttatt gtacccccaa ataatataaa acaaagtatg aaagcgcatc tcaattttaa
     8881 gacttttttg taaattaaga gtataattaa ggtatactgc cttttctata gataatagat
     8941 aatacactaa tataataaag gtctttgtaa catatataaa ttttatttca aggaggaata
     9001 atggaaaagt attttggtga aaaacaagag cgtttttcat ttagaaaatt atcagtagga
     9061 cttgtatctg caacgatttc aagtttattt tttatgtctg tattagctag ttcatctgtg
     9121 gatgctcaag aaactgcggg agttcactat aaatatgtgg cagattcaga gctatcatca
     9181 gaagaaaaga agcagcttgt ctatgatatt ccgacatacg tggagaatga tgatgaaact
     9241 tattatcttg tttataagtt aaattctcaa aatcaactgg cggaattacc aaatactgga
     9301 agcaagaatg agaggcaagc cctagttgct ggtgctagct tagctgctct gggaatttta
     9361 atttttgctg tttccaagaa aaaggttaag aataaaacgg tattacattt agtattggtt
     9421 gcgggaatgg gaaatggtgt cttagtttca gtccatgctt tagaaaatca tcttttgcta
     9481 aattacaata cggactatga attgacctct ggagaaaaat tacctcttcc taaagagatt
     9541 tcaggttaca cttatattgg atatatcaaa gagggaaaaa cgacttctga ttttgaagta
     9601 agtaatcaag aaaaatcagc agccactcct acaaaacaac aaaaggtgga ttataatgtt
     9661 acaccaaatt ttgtagacca tccatcaaca gtacaagcta ttcaggaaca aacacctgtt
     9721 tcttcaacta agccgacaga agttcaagta gttgaaaaac ctttctctac tgaattaatc
     9781 aatccaagaa aagaagagaa acaatcttca gattctcaag aacaattagc cgaacataag
     9841 aatctagaaa cgaagaaaga ggagaagatt tctccaaagg aaaagactgg ggtaaataca
     9901 ttaaatccac aggatgaagt gctatcaggt cagttgaaca aaccggaact cttatatcgt
     9961 gacgaaacta tagaaacaaa aatagatttt caagaagaaa ttcaagaaaa tcctgattta
    10021 gcagaaggaa ctgtaagagt aaaacaagaa ggtgcattag gtaagaaagt tgaaatcgtc
    10081 agaatatttt ctgtaaacaa tgaagaagtt tcacgagaaa ttatttcaac ttcaacgact
    10141 gcgcctgttt caagaatagt cgaaaaaggt actaaaaaag ctcaagttat aaaggaacaa
    10201 gctgagactg gtgcagaaca taaggaagta cagtctggag ctattgttga acccgcaatt
    10261 cagcctgaac taccagcagc tgtattaacc gacaaaggtg agtcagcagt ccaaccagag
    10321 ttgccagaag ctgtagtaag tgataaaggc gtaccagaag ttcaaccagc gttaccagag
    10381 gcagtcatga ctgacaaggg tgatccagag caggtagcac cactaccaga atacacaggg
    10441 gtgcaagccg gagcgatagt cgagccagag aaagtagaag caccgaagga atacacagga
    10501 gtgcaggctg gagcgatagt cgaaccagag aaggtagaag caccgaagga atacacagg
//
LOCUS       DBERCW010000056        10332 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.056, whole genome shotgun sequence.
ACCESSION   DBERCW010000056 DBERCW010000000
VERSION     DBERCW010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10332
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.056"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..223
                     /locus_tag="ACL72M_001938"
                     /pseudo
     CDS             1..223
                     /locus_tag="ACL72M_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            309..521
                     /locus_tag="ACL72M_001939"
                     /pseudo
     CDS             309..521
                     /locus_tag="ACL72M_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            421..867
                     /locus_tag="ACL72M_001940"
     CDS             421..867
                     /locus_tag="ACL72M_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0717005.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1005..2309)
                     /gene="eno"
                     /locus_tag="ACL72M_001941"
     CDS             complement(1005..2309)
                     /gene="eno"
                     /locus_tag="ACL72M_001941"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGS0717006.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2473..2919
                     /locus_tag="ACL72M_001942"
     CDS             2473..2919
                     /locus_tag="ACL72M_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGS0717007.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2916..3719)
                     /locus_tag="ACL72M_001943"
     CDS             complement(2916..3719)
                     /locus_tag="ACL72M_001943"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGS0717008.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3728..4057)
                     /locus_tag="ACL72M_001944"
     CDS             complement(3728..4057)
                     /locus_tag="ACL72M_001944"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGS0717009.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4002..4373)
                     /locus_tag="ACL72M_001945"
     CDS             complement(4002..4373)
                     /locus_tag="ACL72M_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGS0717010.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4432..5865)
                     /gene="glgA"
                     /locus_tag="ACL72M_001946"
     CDS             complement(4432..5865)
                     /gene="glgA"
                     /locus_tag="ACL72M_001946"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGS0717011.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5862..7001)
                     /gene="glgD"
                     /locus_tag="ACL72M_001947"
     CDS             complement(5862..7001)
                     /gene="glgD"
                     /locus_tag="ACL72M_001947"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGS0717012.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6991..8133)
                     /locus_tag="ACL72M_001948"
     CDS             complement(6991..8133)
                     /locus_tag="ACL72M_001948"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGS0717013.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8123..10051)
                     /gene="glgB"
                     /locus_tag="ACL72M_001949"
     CDS             complement(8123..10051)
                     /gene="glgB"
                     /locus_tag="ACL72M_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGS0717014.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELREKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3157 a         2268 c         1813 g         3094 t
ORIGIN      
        1 gaaccacacc tactatgaac aagacccaga aaaagtagcc ttatttctta agaattttaa
       61 tagtttaaag cacctagcac aggtctaaca aatgaatggt gagttaatcg ctccaatgac
      121 ttacgaagag acgatgacga gcgacttttt tgaagcttgg tttcagaaat ttctcttacc
      181 aacattaacc gcaccattgg ttattatatt aaaacgaagt aagaatagga caaatcgatc
      241 aggacagtaa aatctaattc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
      301 aatctactat attaatggac aatgcaagat tccatagaat ggggaagcta gaactcttgt
      361 gtgaagagtt tgggcataaa cttttacctc ttcctcccta ctcgcctgag tacaatctta
      421 ttgagaaaac atgggctcat atcaaaaagc acctcaaaag ggtattacca agttgcaata
      481 ccttttatga ggctcttttg tcttgttctt gtttcaattg actatataaa ttgtctaagc
      541 gaaacaaccg ataagaattg gcacaaaagc gaccgtattt ttgttaccaa tacaggaaaa
      601 ccagttcata gttctatctt gagcaagtct ctccagcgag caaacgaacg ccttaaaaaa
      661 ccaattccca aacatctgtc ccctcacatc ttcagacaca ccactattag catcttatca
      721 gaaaataaaa ttcctttaaa aacaatcacg gacagggttg gtcattccga ctctgaagtc
      781 actacttcca tctacaccca cgtcacaaag aacatgaaag atgaagcaat caatgtactg
      841 gataaagtta tgaaaaagat tttttaaaaa gttttgtccc ttttttgtcc tctaaataca
      901 aaaatagccc ttcggataaa atccgagggg ctagaaacgt tgttaaatca acggccgaac
      961 ttttgaattt catggttcgg gataaaatag ttcactgaac tattttattt tttaaggttg
     1021 tagaatgatt tcaatccacg atattcagct acttcaccaa gttggtcttc gatacgaagc
     1081 aattggttgt atttagcgat gcggtctgta cgtgaaagtg aaccagtctt gatttgtcct
     1141 gcgttagttg caactgcaat atcagcgatt gttgaatctt cagtttcacc tgaacggtgt
     1201 gatacaacag cagtgtaacc agcttcttta gccatttcga tagcttcaaa agtttcagta
     1261 agagtaccga tttggttaac tttgataagg attgagttag cagcaccttc ttggatacca
     1321 cgtgcaaggt agtcagtgtt tgttacgaag aagtcgtcac caacaagttg tactttctta
     1381 ccaagacgtt cagtaagagc tttccaacca tcccagtcgt tttcatccat accatcttca
     1441 atagtgatga ttgggtattt gttaaccaat tcttcaaggt agtcgatttg ttctgcagat
     1501 gtacgaacag cagcaccttc accttcaaat ttagtgtagt cgtaaacttt acgttcttta
     1561 tcgtagaatt ctgatgaagc acagtcaaat ccgataaata cgtctttacc tggtacatat
     1621 ccagcagctt caatcgcagc aaggatagtt tcaacaccat cttcagttcc ttcgaaacga
     1681 ggagcgaatc caccttcgtc acctacggca gtttccaaac cacgtgattt aaggattttc
     1741 ttaagagcgt ggaagatttc agcaccgtaa cgaagggctt ctttaaatgt tggcgcacca
     1801 actggcaaga tcatgaactc ttggaaagcg attggagcgt cagagtgaga accaccgttg
     1861 atgatgttca tcattggagt tggaagaact ttagtgttga atccaccaag gtagctgtaa
     1921 agtgggattt caaggtagtc agcagcagca cgagctacag cgatagacac accgaggatt
     1981 gcattcgcac ccaatttacc tttgttagga gtaccgtcaa gtgcaatcat agcacggtca
     2041 atagcttgtt gatcacgtac atcgtagcca atgatagctt cagcaatgat gttgtttacg
     2101 ttgtcaacag ctttttgtgt accaagacca ccgtaacgag atttgtcacc gtcgcgaagt
     2161 tcaactgctt cgtgttcacc agtagaagct cctgatggaa ccataccacg tccgaaagca
     2221 cctgattcag tgtaaacttc tacttcaagt gttgggttac cgcgtgagtc taggacttcg
     2281 cgagcgtaaa catcagtaat aattgacatt ttttactctc cttatgagtt aaatttttta
     2341 cacctctata ataccttaaa acccctcctt tttcaagaaa aaacgttatc tttgtgcaac
     2401 ttttccttaa ctttataaag taatcgcttt cttttgtctg ttttattcta acttttatga
     2461 tatactgttt tcatgacaga tttatcaaaa caattacttg aaaaagctca tggtgggtta
     2521 aaaataaatc cggatgagca aagacgctat cttggtactt ttgaggaaag agttcttgga
     2581 tatgtagata ttgacacagc aaatagccct cagttagaaa aaggcttttt atttatttta
     2641 gaaaaccttc aggaaaaagc aaagccacta tttgtgaaga tttcaccaac tatcgaattt
     2701 gataagcaag ttttctactt aaaagaagca aaagaaactg atagtcaagc caccatagta
     2761 tctgaagagc atattacttc tccttttggc ctggttattc atagcaatgc accagttcaa
     2821 gtagaagaaa aagaccttcg acttgctttt ccaaaacttt gggaagttaa aaaggaagaa
     2881 ccagccaaaa catccttatg gaagaaatgg tttagctaaa tcttgcacat atttaataag
     2941 tgcccaatat tggcagccgt gcgctccaga tagagactgg catttttcaa actatcttct
     3001 aaaggttcac ttttctccaa aatagaaaag acagcttgga tattttcaaa tggtagggga
     3061 ggtaaatctt cagcaagact accgcaaata gcaataacag gaactccaac aggggttctt
     3121 tttgcaacac ctataggcgc tttcccagca aagctttgac tatcaagtct tccttctcca
     3181 acaacaacca agtcagcatc tgaaactttc ttatcaaagt tgattaagtc caagcaggta
     3241 tcaattccag acacgatact tgcctgagca aaggcacaca aaccagcagc aatccccagt
     3301 cctccatcat tactggccgt gccaccaaca ccgatataaa tatctttaat ccctttagaa
     3361 atgagatgga gaatcaactc tccaatacca caagtttgga tttgaagtgg atttcgtttc
     3421 tctagcggaa tttttccaag accaaccaag tcagctactt caaatagtgc cagttcccct
     3481 ttttgaaaat agcgcatggc ttctttttgt ccaaaagggt ctgtcacttg gatccatttt
     3541 tcttttaggt caagagaatg tcggatagca tctacagtac cttctccccc atcaccaaca
     3601 gggcagagga gacattctac atctgctatc gattgttgga agcctctttt tattgcttca
     3661 gctacctgtt gagctgtcaa gctttcctta aacgaatccg gtgcaattac aatcttcata
     3721 ttttccctca ttctaaacag tcaatcaaag gaagaacttc taaaaaatcc ctcttgtcaa
     3781 catgatgtgg tatttctttt ttgagcattt ctttggaaca aaaggcgatt cctaactccg
     3841 ccgacttcaa cattaataga ttattaaccc catcaccgat tgccaccgtt ctttctttag
     3901 aaagttttag tttctttctc catttttcca gagtttcttt tttgacctgg ggacttataa
     3961 tttgtccaac taattttcct gttaaaagac cttctttgac ttcaagctgg ttggcagtga
     4021 aataggcaat accaagggat tttgctaatc tctccaacta ttggtgtaaa tccaccagac
     4081 accagaccaa ctaggatgcc attcttttgg agaatagaga tgaactctgg gacatttagc
     4141 gatagatgaa ttgagttgaa gacgttatca aagaccaaaa taggaagacc ttccaacaag
     4201 gacactcttt ttcttaaact gctttcaaag accaactctc ctcgcattgc tcgacttgta
     4261 atctgcgaaa tttccgcctc atgacctgcc tctctcccta aaagatcaat cacttcttct
     4321 aggattaagg ttccatctac atccaaaaca cacaagcctt ttacttgaga catcagttct
     4381 cctctctaaa cagcctaaaa atcgtatgaa gtcatcatac gattttatct attaattaac
     4441 taaactatgg tacaagtcaa ggtatgactt gcaggctgta tcccatgaga agtcactctc
     4501 catagcttgt ttttgtaggt ttctccaaat gtctggatgg tttctataca agtccaatgc
     4561 tgtttggaaa gtccaattta accaataagg agatagattg tcaaagctaa agccagtacc
     4621 gcttccttcg attggattga aagcgcgaac tgtatctcgc aagcctccaa cttcatggac
     4681 caatggcaag gttccataac gcatagccat catttgagac aagccacacg gttcaaaacg
     4741 acttggcatg aggaagaggt cacaagcagc gtagatttcc tgagcaagtt tgacatcaaa
     4801 agtgatattt gctgatagct tgtctgggta aatctgagca aaccatgaga aagctccttc
     4861 aaaggctgga tcgccagttc ccaaaagaac aatctgaaca tcttcttgca agatatggtg
     4921 aagactttcg accaccacat caaaaccttt ttgacgtgtc aaacgagaaa caattcccac
     4981 cagtggaacg tctgctctaa caggcaagcc aactctttct tgcaattttg ccttattttt
     5041 ggctttccca gacaaatctt cctgattgaa atgatagtct aaaagagcat ccgtctgagg
     5101 attataaaga tcagcatcaa tcccattcac gataccagat actttaccag actccatttt
     5161 aagaatctga tccaaattac atccaaactg actagtcata atttcatgag catagctagg
     5221 tgaaacggtt gaaacacggt tcgcatagag aatacctgcc ttcatccagt tcagacagtt
     5281 gttccatcga agggtgccat cagcgtaacg ttcaaggcca actccaaaca aatcacccaa
     5341 cattccttct gaaaattgtc cttggaattc taaattatga atggttaaaa ctgtttcaat
     5401 gtcctcatag gcttgaatcc aacagtattt ttccttcaac aagaaaggaa tcatagctgt
     5461 atggtagtca tgaacatgga gaagatcagg aataaagtca atcctttcca tagcctcaat
     5521 ggcagccagt tggaaaaagg caaagcgttc tccgtcatca aaatcaccgt aaacatgacc
     5581 acggaagaaa taatattgat tgtcaataaa gtagaaggtt acaccattta atactgtttt
     5641 cttaattcca caatactgtc tacgccaacc aacgctcacc tcaaaatgaa gcacatcttc
     5701 aatctgattt ccaaatttag cctctaccat atcatagtag ggtaaaatca ctgcaacttc
     5761 gtgcccagct tttaccagtg attttggaag agcgccaatg acgtctccca aaccacctgt
     5821 ttttgaaaag ggtgcaccct ctgctgctac aaataaaatt ttcatgaatg aatatcctct
     5881 gttactttag cacctttctt aaccacaact ggatgttctg cagttcctcg aatcacaaca
     5941 ccaagctcaa cttcaacccc tttgtccaag atagcatatt cgacctgagc cccttctcca
     6001 ataacaacac gagggaagag caggctatct ttaaccaagc tatccttatg gacatgaata
     6061 ttacgtgata gaacagaatt agctacttga ccttcaataa tactaccaga ggcaaactga
     6121 gaagtgctta ccttagatgt attagcatag taagttggct cttcgttttt gacctttgta
     6181 taaatctttt ggtttggtga gaaaagagaa tagaattttt gtgattcaag catatcgata
     6241 ttcgcttgat aataagattt aacagagtga atattggcta gatagcccgt gtactcgtag
     6301 gcaaaagctc cctcttttac agccaaatcc cgtaaaacat agcgcaattt ctctggatgt
     6361 tcttttttag cttcttcttc caagtgttca atcaaccaag gtgtatcaac gacaaagata
     6421 tctgtagaca tattgaacgt ttcagctgtt gacttgctat caaagagttt atgagaaaga
     6481 acatggtctg tttcatctac atccaagatt gcatttactt ctgaaatatc tttcttagct
     6541 agttttttat aaactacagt gataggctct tttgttgtac tatgtaggtg gaaaacttgg
     6601 ttcaaatcaa tgttaataag aacatcgcag ttgagggcaa ccgtttggtt tgagccagaa
     6661 cgtttcaaat aagtaagaag ctgttggtag tattcttttc caactgtact actttctaca
     6721 cgggtattgt aaattcctag atagtaatgg ctaagaaggg ttgataagcc ccactcgcgc
     6781 cctgaacgaa tatggtcaaa gactgagctg atattatcct gctggaaaat accaaagaca
     6841 ctacgaacac ctgcattagc aaggcttgaa agtgggaagt caatcaaacg atatttccca
     6901 ccaaatggca aacttgctac tggacggtgg tccgtcaatg tcgacatatc gtgaaaacca
     6961 actgtatttc ctaaaatggc agaatattta tcaatcttca tctgttgcta cccccactac
     7021 ttcattatat cctacaactt gtacttcatc tgttccatca atttcgacac cgtcagaaat
     7081 aatcgcacct tcaccaataa tggcacgttt aatcttagct ccttgaccaa tgatagctcc
     7141 actcatgata actgaatcaa ggacttccgc tccttcgcga acttgcgcgc ctgttgaaag
     7201 gatagaatgt ttaacagttc catcaacgaa acatccgtct acaactaatg agtcttccac
     7261 atgagcattt gccccgagga agtttggtgg tgaaatcaag tttcttgagt aaatcttcca
     7321 ttgacggtta cgactatcca aggcattttc tggagaaata tactccatgt tcgcttccca
     7381 aagtgactca atagtaccaa catctttcca ataaccacta aattcataag cataaacact
     7441 ttcacctgac tcaaggtaat ttggaatgac atttttacca aagtctgaca tgccaacctt
     7501 gctcttttca gcagcgacta acatattacg aaggcgttgc caatcaaaaa tgtagattcc
     7561 catagaagct tttgtagatt taggttgagc tggtttttct tcaaattcaa caatacgatt
     7621 gttagcatct gtgttcatga taccaaaacg gcttgcttct ttaagaggga cgtctaaaac
     7681 tgctactgtc aagctggcat tattatcctt atgagactgg agcatatcat catagtccat
     7741 tttgtagatg tgatccccag acaaaatcaa gacatactca ggattgacac tgtcgatata
     7801 gtcgatattt tggtaaatag cgtgactagt cccctcaaac caacgatttc cttcacttgc
     7861 agaataaggt tgaagaatag agacacctga attaataccg tctagtcccc agcttgaacc
     7921 attcccaata tggttgttga gagcaagtgg ttgatactgt gtaacgaccc caacattatg
     7981 aatccctgag ttggcacagt ttgatagggc aaagtcaatg atacggtagc gcccaccaaa
     8041 ttgcacagct ggttttgcga tgctttgagt gagtttaccg agacgagttc cttgcccacc
     8101 agcaagaatc aaagctaaca tttcattttt cattttctac tcctttttgg tttttatttg
     8161 tgacggtttt agtagatttc aagcgacgtt tgattttcca tacacttgct cccatagccg
     8221 gtagggtaaa ggttaaggtc tgctcataat ctttccatag tccttcttgc gtttgaacag
     8281 tttgattatg ttctttccaa acgcctcccc actcttccaa ctcagtattc catacttctt
     8341 cgtaaattcc tgcaacgggt agtccgattg taaaatcttt ccgctcaaca ggtaccatgt
     8401 taaagataca gactaacatt tctccctttt tacccttacg aataaaggaa agaacactct
     8461 ggtctcgatt atccgcatca atgatttcaa taccatcata gctggtatcg atttcccaca
     8521 gacagcgatg atctttgtaa aactggttta gctgagaagt gaaatacttc atcttagcat
     8581 tcattgggtc ttctaggtta gaccattcca actgttcttc agatttccat tctaggaatt
     8641 gaccgtattc gctacccatg aagagcaatt tcttaccagg atgacaaatt tggtacgtat
     8701 agagattgcg caagcctgcg aattgattgt aacgatctcc ccacatctta tgcatcatac
     8761 tcttcttgcc atgaaccact tcatcgtgcg agaatggcaa gagataattc tccttgaaaa
     8821 catacataaa gctgaaagtc accaggttaa agtcatattt acgatagatc ggatcttctt
     8881 cgtagaaacg gaggatatca ttcatccagc ccatgttcca tttgtagtca aatcctagac
     8941 caccaatctc tttcattccc gtaatcttgg tcgcagacga actttcttct gcaatcatca
     9001 tcacatctgg atattctaac ttaataacct cattcaagcg ctgaaggaaa taataacctt
     9061 catagttgag atttccgcca tctttattag gtgtccatgg agcatcatca tagtccaaat
     9121 agagcatgtt gctaacagca tccacacgaa taccatccaa atgatagaca tcaatccaat
     9181 gcttaatgca agaaattaag aaggactgga cttcattttt tccaaggtca aaattaaggg
     9241 caccccaacc atggttatga gccttattat ggtcttggta ttcaaaagtc ggtgtcccat
     9301 cataataggc taaggcatca tcgttgatgg taaagtgacc tggtacccag tccacaataa
     9361 ccccaatatt atgggtatga cactcctcga caaaatcttg aaactcctct ggtcggccat
     9421 aagcatgctc taaagcgaag taacccataa gctgataccc ccaactcaag cccaaaggat
     9481 gggacatcaa gggcataaac tcaatatgag tatagttcat ttcaacgaga taaggaatga
     9541 gttcatcctt gagctgggca aaactataag gactgccatc agaatttctt ttccatgatc
     9601 cagcgtgaac ttcataaata ttgacaggac gctcttcaaa gccccaacgt tttcttcgtg
     9661 ccagccaaag tccatccttc catttcttct cacgaagctc tgttaagatt gcccctgttc
     9721 ctggacgagc ctcatacctg acagcaaaag ggtcaatctt catcagttga tgaccatttt
     9781 gacgtgtgac atgatatttg taaatatgcc cttcttgagc catattggta aagacttccc
     9841 agaccccaaa atcatttctt accattggaa tctgattttc aatccagttg gtaaaatcac
     9901 caaccaagtg aacagcctga gcattaggtg cccaaacacg gaaggtatag ccatgctctc
     9961 catttagttc ttccctatgt gctcctagat aatgttggag ataaaaattt tcacccgtca
    10021 taaaggtttt taatgcttct ctattatcca tatactcccc ttctcctgta agcgttttct
    10081 atgtttttat tatactacct ttttagagaa gattcaagta aattactata cttctttaat
    10141 tattttgaaa atctacaaca agttcactta ctcgttcaat tgtaaatcaa tattttttca
    10201 aaaaattgcg aaaactcctt tctttttcta ctatagtgaa atgaaataaa acatgcgcaa
    10261 atcgattaag gaatttaatc taatttctaa caatgtctta gaaatcaaag tgtactattt
    10321 taactccaat gt
//
LOCUS       DBERCW010000057        10233 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.057, whole genome shotgun sequence.
ACCESSION   DBERCW010000057 DBERCW010000000
VERSION     DBERCW010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.057"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            77..751
                     /locus_tag="ACL72M_001950"
     CDS             77..751
                     /locus_tag="ACL72M_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGS0717015.1"
                     /translation="MDSNFAGRLNILRAGVLDANDGIISIAGVVIGVASATTNIWIIF
                     LSGFTAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GEFKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSDYRIPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(793..2781)
                     /locus_tag="ACL72M_001951"
     CDS             complement(793..2781)
                     /locus_tag="ACL72M_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0717016.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFTKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2783..3541)
                     /locus_tag="ACL72M_001952"
     CDS             complement(2783..3541)
                     /locus_tag="ACL72M_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0717017.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3969..4160
                     /locus_tag="ACL72M_001953"
     CDS             3969..4160
                     /locus_tag="ACL72M_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717018.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4514..4786)
                     /locus_tag="ACL72M_001954"
     CDS             complement(4514..4786)
                     /locus_tag="ACL72M_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS0717019.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4845..5294)
                     /locus_tag="ACL72M_001955"
     CDS             complement(4845..5294)
                     /locus_tag="ACL72M_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGS0717020.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            complement(5281..7410)
                     /locus_tag="ACL72M_001956"
     CDS             complement(5281..7410)
                     /locus_tag="ACL72M_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGS0717021.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            7780..7911
                     /locus_tag="ACL72M_001957"
     CDS             7780..7911
                     /locus_tag="ACL72M_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGS0717022.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            7912..8817
                     /locus_tag="ACL72M_001958"
     CDS             7912..8817
                     /locus_tag="ACL72M_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGS0717023.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            8814..9629
                     /locus_tag="ACL72M_001959"
     CDS             8814..9629
                     /locus_tag="ACL72M_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGS0717024.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTNLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(9759..>10233)
                     /locus_tag="ACL72M_001960"
     CDS             complement(9759..>10233)
                     /locus_tag="ACL72M_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0717025.1"
                     /translation="LILLDGGYLDLDKILPLDTELEETKNYIKSQIISDLDVLTSKEK
                     SEAKHWSENMEKAVRQSYHWNVEYNRYELAINYENIEAILRLRRKIQAFKREVGDTLF
                     ISPRYPNEATWREEALKELPDYFDTIFLENFGHELYTQAPKEIASLMNEWLAYFL"
BASE COUNT         3016 a         2150 c         1964 g         3103 t
ORIGIN      
        1 gactacaagt cacccagaga agacttctgg atggctaact tgaacttgaa atttagcgtc
       61 agaaacaaat cacgaaattg attcaaattt tgcaggtcgt ttaaatatcc tgcgtgcggg
      121 tgttcttgat gctaacgatg gaattatttc cattgctggt gtggttatcg gagttgccag
      181 tgccacgacc aatatctgga ttatcttttt atcaggtttt acggctatct tagctggtgc
      241 cttttcaatg gctggtggag aatatgtatc cgtttcaact ccaaaagata ccgaggaagc
      301 tgccgtttcg cgagaaaaac tcttgctaga ccaagatagg gaactagcca aaaaatccct
      361 ctatgctgct tatatccaaa atggagaatt caaaacttct gcccaactct tgaccaataa
      421 gatctttctt aaaaatccac tcaaggctct ggtagaggaa aaatatggga ttgagtatga
      481 agaatttacc aatccttggc acgctgccat ttctagcttc gttgcctttt tccttagaag
      541 tttgcctcca atgctgtcag tgaccatttt tccaagtgat taccgcatcc ctgctaccgt
      601 ccttattgtc ggtgtggccc ttcttctcac tggttacaca agtgctagac ttggaaaagc
      661 cccaaccaaa acagctatga ttcggaacct tgctattggt ctcttgacca tgggagttac
      721 cttcctgctc gaacaacttt tcagcattta gaatacaaga aatacctcga ttttgaagtc
      781 gaggtatctt ttttacattt gcacaatctt gcgataactt cttgaagtaa tcatgaaaat
      841 cagcacatag gcgatgagga agatagcgca gatagacaag gtcacaatca acatcatagt
      901 cgtatccagt acaccaatca cttttaaaat caggctaagc atatggtagg caaaggcgag
      961 atgtatgaag gcaaagagca aaggaaggaa gaaaacagtt aaaacctgtt tgttgatggt
     1021 ttgcttgatt tgcttttggt ccaaaccgac tttctgcaag ataataaagc gttcacggtc
     1081 ttcgtagcct tcagaaattt gtttgtagta gatgaccaga acagttccga ccataaagat
     1141 aatggatagg aaaataccga taaagaagac accaccaaag agggcactca tctgagaact
     1201 agcatctgct agattgctac cataaacata gctaccttct gtgtctaatt gagcattaaa
     1261 ttgattgagg tagttttcat actcctcagc gaccttgagt tgttcttctt cgctggcatc
     1321 tacattcata ccaccgtaaa actgattata gatagccgaa tctgggaatt gatccaaaaa
     1381 ggcttgtaaa tcaggaacaa caaggtaatt gtaatcagta gtcaagatat taaacttatt
     1441 tggaacatgg ttgacaataa aatctttagt aaattcttct ttgacagaaa attgatgatc
     1501 atttagagtt agagctttct gtcctttcag tccgtcattt ttggcaaaga gaccgacctc
     1561 atttcctgat agagacagtt tttgaccagt catattttca taatcttttt ggtcaaatac
     1621 catgaaaact gtttttggtt ggacacggtt ttgtcctttt tcaaaaatag ttaacttggt
     1681 tccttcttga ttcgcaacag caaagtaagt gtaacgaaat acttcttttt ctttaatctt
     1741 ataacctttg tcacttgcaa actggctcaa gagtttgtcc aagtcttctt tttcaacatt
     1801 ttgccctgaa accccaaaat catgaggatt tagaactttt ttaaagcttt ctgaggaatt
     1861 gaaaatgctt gtcgctgctg acatggttac caaaaccatt gttgacaaga tagcgatggt
     1921 ggctagtcca actgcatttt tcttcatacg gaaaatcaag ttagaaacag atatgaggtt
     1981 atttggttgg taatagtatt tcttattttt ctttaagatt tggaggaaaa cggtaatccc
     2041 tgcattaaac aagagataag tcccaaagat aaccagtaaa acagctatga agaaggttgt
     2101 taaggctgta agaggatctt ttaccgtaag ggcaagataa tagccaattc ctaaacttat
     2161 ggaaccaaga atggtttgga gaggaaggaa gcgacctttt ttctctccac tagctttctc
     2221 acgagagagc tggagggcat tcatacgggc gattcgaagg gcattcagga acatgaggcc
     2281 taggaaaatc aaaccgaaga caacaagcac tgtaatgaca actttcgtct ggaaggtagc
     2341 aaccagctca accttcaatt tcattagttt gagcaggaaa gcgaaaatta acttgtcaaa
     2401 caaggctcca ataccgatac ccgctccaac agttagaatc ccaaatacca ctaactcctt
     2461 aaaggtcata ctgataagat gacgcttctc caagcccaac atgccataaa ttcctagttc
     2521 cttggaacgg ttcttcatga caaaactatt ggcatagaga acgataatgg ctgacgcaag
     2581 ggtgacgaca aacataccaa atccaagtgt agcctgaatg gttgttcctc cacggatttc
     2641 cgcaatctta ggattgaagg ttagagagta aaagagatag gtgacagtga ctgccaagag
     2701 aacagccagc gcaaaaggat agtagagttt gcggttttta atcaagttcg ataccgctaa
     2761 cttattggtt aatcgaaaca tactaattca cctcgcttgc catgacagtc aaggtatcag
     2821 agatttcttg gaacatctga cgttctgtct tctctccacg gtagatttga ttgtaaagaa
     2881 tgccgtcttt gataaagagt acacgtttag ctctgctagc tgctgctgtt gagtgggtta
     2941 ccatgagaat ggtttggccg cgctcattga tttcatcaaa gacatcaagt aaggctgcag
     3001 atgacttgga gtcaagagct cctgtcggtt cgtccgcaag gagaatttca ggttctgtga
     3061 tgatggcgcg ggctactgct acacgctgtt tctgaccacc agaaatctcg taagggtact
     3121 tctcttgtaa ttggtttatt cccagattct cagctgtcac caccaatttc ttcatcatct
     3181 ctgtaatagg tcttcttgac aagacaagcg gaagcaagat attgtccttt acagatagag
     3241 tatctagcaa gttaaagtct tggaagacaa agcccaactt ttcacgacgg aagctagagg
     3301 cctgtgaatt tttaatggtt gcggtgtcag ttccattcaa gtaaacctga ccacgacttg
     3361 gtttatccag catagctaga atattgagaa gagttgattt accagaacca gactcaccca
     3421 tgatggcaac gtagtcaccc ttttcgacgg taaagtgaat atccttgagg gcttctactt
     3481 ggttgccctg aaaacgtgtt ttataaattt tttgaacgtg ttttacatct aaaagtgtca
     3541 tgagaatctc ctttcttaat atcccatcaa atgaaatgta gcttgcatca tagtgcatcc
     3601 cagctgaacg cgctcaattt ctttgtgact tggttttcta gttttcttat gtaagatttg
     3661 tttcatgatg ttactccttt gttctttatg agtctagttt acatcaaaaa aagaccgctt
     3721 gccataacct aaccttacaa aagagacttt aatcttacat ttttgtaaga ttgggtgaaa
     3781 tataagcaaa attacttaga aaatgatttg atttcctatt tttaaagttg taaaatataa
     3841 gtgtgaaaag gcttactttg aaaaggagga agcgggaact aacattttag taaggttacc
     3901 tagataacat accattcaat ttaacacttg caagtcgttc aacctataag gaaagaaggt
     3961 gcgctttaat gaaacacaaa gaacatatac tcatcggact tctctatctg ctctctccat
     4021 tcatcggtca gctcttagtt gaacacacac actttatcgg tacagaattt accggcactg
     4081 cttatgttat ttgctggtta tcagttgtta tcagcatcca ccatttttcc aaaaatgtat
     4141 tgtctcagca gcaaaaatag attaaaaaac tgagtttaaa ttactgcttt tataataaaa
     4201 tgaaataaga acaggacaaa tcgatcagga tagtcaaatc gatttctaac aatgttttag
     4261 aagtagaggt gtcctattct agttccaatc cactatagtt tgtggatgaa gctggcgaaa
     4321 tattattaat actattcaaa aatcaaagtg caaactatgt caacttcaca ttgccgacta
     4381 aattacagcc tgtggctggc ttcctagttt gcactttgat ttttattgag tataaaagta
     4441 aaaaagcttt aaatcaagca gtttagacta ttgatttaaa gctttttgct tattccaaat
     4501 cttctgtaga acctcaccaa aaccagcctt cattgtcgtc aatggcttgg gcttctttgc
     4561 gtttacgtgg gcctgttccg tacatttctg cttcgatttc ttccttggta ggcatgatag
     4621 aagctaggat gatatagata atcacgccaa gtccaaagtt tgcaactgta aaaatagcaa
     4681 acaagaaacg aactagggta acatcaaaat tccacttgtc tgacagacct gccagaactc
     4741 ctgaaatcat gcgattgcgt ctcattttat aaaatttact gttcatgata tttcctcttt
     4801 ctgctaggtt agacatagta tatcacgggg aggctcggct ttcatcagtc ctcaggctga
     4861 tttatcagaa gcaatttacc tcgacaaagt ccacagcgat agcgtttggt atcaatccta
     4921 cgcttgcgct gatacctttg ctggcaggat tgacaacgat aaagcttgag tggtttagag
     4981 ttactattgg gcaaggatgg tacaaaccgt aatccatcca ctgctttcaa aagttcctta
     5041 aaatcccgat ccttgtgttg atagcccttc ccttggaaat aaaggtgata atgacagagt
     5101 tcatgtcgga caattttcct aaaaacctcc atacccagtt tctgataaac cttgggatta
     5161 aaatccagat gcccatcttt ggggaaaaat cgcccacctg tcgaacgtag acgcctattc
     5221 cactggacat gatggataaa agctctcccg aagtcttcta gtgaaacctg cttgacataa
     5281 tcagtcagtt tcatttggag cgaggagcga cagattaact ttttcacgtt cagtatcaat
     5341 tttcttgacc caaacggtca ccaaatctcc aactgccacc acttgactag ggtgtttgat
     5401 aaacttgcga ctcatatgag aaatatgaat caagccgtcc tcgtgaatcc cgatatcaac
     5461 gaaggcaccg aagtcaacaa cgttacgcac aacaccttct agcttctgac ctaccactag
     5521 gtctttgata tctaggacat cttggcgaag cacaggtgcg tcaaaggaat cacggaaatc
     5581 tcgacctggt ttgagaagat ctgcaatgat atctttaagg gtttctggac cgaggtctag
     5641 ctcttgagcc atttccttga ctgaaagcga cttgagtttg ctttgggcct cttcattcag
     5701 atccttaatg tccaagcatt tgaagagttc cttaacggca gcgtaatttt ctgggtgaac
     5761 tcctgtatta tcaaggatat tgctactttc agggatacgg aggaaaccag cagcctgttc
     5821 aaaagccttg gcccccaaac gaggaacttt cttgatttgg gagcgtgaag tgatttttcc
     5881 ctcttcctca cggtatttga cgatattttc agaaatggtt ttattgagtc cagctacgtg
     5941 tgaaagaaga gctgggctag ctgtattgac attgacacca acttggttaa ccactgtatc
     6001 gacaacaaag tccagactct cagatagttt cttctgactg acatcgtgtt ggtattgacc
     6061 gacaccaatt gacttaggat cgattttgac caattccgca agaggatctt gcaaacgacg
     6121 ggcgatagaa atggcagagc gtttttcaac ggtcaagtct ggaaactcct gacgagcaag
     6181 ttcgctggca gaatagacag aagcaccact ttcattaacg ataacatagc tgacttcagg
     6241 gaaatctttc agaacttccg ctacaaaagc ttcactttca cgactggccg ttccatttcc
     6301 aatggcaata atctctacac cgtattgacc aattaaatct gctaaatctt tcttggcttc
     6361 ttcgatttga cgagctgatg ctggtttaac aggataaata acctgagttg tcagcatttt
     6421 tcctgttgca tccacgacag ctagcttggc acctgtacga aaggctgggt caaacccaag
     6481 aaccacgcgc cctttcagtg gagcaaccaa gaggagattg cgcagattgt cagaaaaaag
     6541 ttggatagct ccctcttcag ctttctcagt taattctgtc cgaatacgac gctcaatagc
     6601 aggcaagacc tttttcttaa cggattgctg aacaacttca tcaatataag catttttcac
     6661 cttgaaacga gtagcaaaga aggcaagaat acggtccgtc gcatgttcaa aaccgatctt
     6721 caagacacca agtttctccc cacgattgag agccaaggta cgatagcctt gcatagttcc
     6781 aactgtctct gaaaaatcat aataaatctg aaaaacctgc ttttcatcaa gactttcatc
     6841 cttggcttga gaagtgagtt tagagtgtct cagcacttcc tgataagtca tagaacgcaa
     6901 ggtcacatct tccgataagg cttcgaccaa aatatcaact gcaccggtca aggcttcctt
     6961 gccagtcgca aatccttcac agacgaactt ttcagcttct ttctctaagt caactatatt
     7021 ctgcaaaatc aaacgagcaa gaggaaagag tccagcttca cgggcaatgg ttgccttggt
     7081 acgacgcttt tccttataag gaagatagag ttcttcaacg tctgctaatt tttcggcaac
     7141 taagatagct tcttccaatt ccttggtcaa cttaccttgt tcttgaatct tagctaagac
     7201 agcttcctta cggtcattga gatttgtcag acttttatcc aaatcaataa tagccttaat
     7261 cgccacctca tccagactac cagtcatgtc cttgcgataa cgcgcgataa agggaatagt
     7321 cgccccttca gctgtcaaac ttagaacggt atcaatttgc tttaacgtca ctcccaaatc
     7381 ctgagagatt ttttcatatt ttttatccat aaatctatta taccacaagc tggaaggctt
     7441 tctccaatcc ttttcatact caataaaaat caaaaagcaa actaggaagc tagccgtagg
     7501 ctgctcaaaa tactgttttg aggttgtgga taagactgac gaagtcagct caaaacactg
     7561 ttttgaggtt gtggatagaa ctgacgaagt cagctcaaaa cactgttttg aggttgtgga
     7621 tagaactgac gaagtcagta accgtactac ggtaaggcga agctgacgtg gtttgaagag
     7681 attttcgaag agtatcaact atcgaaaaca aattaaaaaa ctcccttttc cgcaaaataa
     7741 tagtataata gaggtagaat ttagaatcga ggtacaccta tggctgtcaa atttacaaaa
     7801 cgagacgact tggacaagat gtttgaagag tttgctaaac tccctgattt gaaacaagtt
     7861 actttccctg atgacaaaga gaaaaaagtc aaagcagaaa agaaaaacta gatgactgct
     7921 tttcaacaac tcccatctag tgtacttcaa actggagcca tttttctctc cattatcatt
     7981 gaagcccttc ccttcgttct gataggaagc attgtctcag ggctgattga agtttatatc
     8041 acacctgaca aggtttatca ttttctccct cgaaatcgtt gggggagaat cttttttggg
     8101 acctttgtcg gtatactttt cccttcttgt gaatgtggaa tcgtccccat catcaatcgt
     8161 tttctggaaa aaaaggttcc aagttacacg gccgttcctt ttcttgtgac agcacctgtt
     8221 atcaatccca ttgttctttt tgcgacctat tctgcctttg gcaactcctt ccatgtcgcc
     8281 ctattacgag ctctgggttc cattcttgtg gctgtaatac taggaatttt tctaggattt
     8341 ttctggcaag aaccgattca gaaagaaaat cgtctggctt gtcatgagca tgatttttct
     8401 tacttgagtt ctgcaaaaaa agtttttcaa gtctttgtgc aggccattga tgaatttttt
     8461 gatacggggc gttatttggt atttggctgc ctctttgctt ctataataca ggtctacgtt
     8521 ccgactcgga ttctgacctc tatcagtgcg acccctcttt ttgccatcct gctcttgatg
     8581 attttagcct ttcttctttc gctctgtagt gaggcggatg cctttatagg tgcttctctt
     8641 ctctcgagtt tcggtttggc accagttctg gcctttctcg tcattggtcc aatgctggat
     8701 atcaaaaata ttctcatgat gaaaaattac ttgaaagcac gatttatcag tcacttcata
     8761 acaattgtaa ctcttgtcgt cttagtctat tctctcttga ttggagtcat cctatgattc
     8821 gatttttagt tttagctggc tattttgaac tgactattta cctccatctg tcgggcaaac
     8881 taaaccagta catcaacatg cactattcct atctggccta tatctccatg gtgctttctt
     8941 ttatcttggc tatcgttcaa ttgtatatct ggatgaagca agtcaaaacc cacagtcatc
     9001 tgaacagccg attggccaag atgacgagta tttctcttct ggctattcca cttgtcatcg
     9061 gcttaacttt cccaactgtt agcttggatt ctcagactgt ttcagctaaa ggctatcatt
     9121 tccctctatc ggaaggaacg aatctggcta ttcagacaag tgaagggact acaagccaat
     9181 atttgaaacc agatactagt tcttattttt caaaatcagc ctatgaaaag gaaatgcgaa
     9241 cggcggcgga taaatactta tcccaagaca gcattcagat cactaatgaa aactatatgg
     9301 aagtcatgga ggctatctac gactatccag atgagtttga gggcaagaca atccagttta
     9361 caggctttgt ctataacgac cccagtcatg ccaatagtca atttctgttc cgattcggca
     9421 ttatccactg tatcgcagat tctggtgtct atggattgct gaccaagggc aatacccggc
     9481 agtatgaaaa caacacttgg atttcagcca aaggaaaact ggtcaatcac taccataaag
     9541 aactcaaaca aaaccttcca accttggaaa tcgacagctt taccaaagtc gataaaccag
     9601 aaaatcccta tgtatataga gctttttaag aaaatcaaga taaaaacgaa caagttctct
     9661 tctgaataac agaaaaagag cctgttcgtt ttttggttat atgaaaatta gtgacttgta
     9721 gattttcatc ttataccatt tccagcaata caagtagctc atagaaaata agcgagccac
     9781 tcattcatta gactagcgat ttctttaggt gcttgagtat aaagctcatg gccaaagttt
     9841 tctaaaaaaa tagtatcaaa atagtctggc aattctttta gggcttcctc tctccatgta
     9901 gcttcattag gatagcgagg actaataaac aaggtatctc ccacttctct cttaaaagct
     9961 tgtatttttc tccgtaggcg gagtatcgct tctatatttt cataatttat agccaactca
    10021 tatctattat actcaacatt ccagtgatag gactgtctta cagctttctc catattttct
    10081 gaccaatgct ttgcttcaga tttttcttta gaagtaagaa catctaagtc cgaaataatt
    10141 tgagatttga tataattttt agtttcctct aactctgtat ccaaaggtaa aatcttatct
    10201 aaatctagat agccaccatc caaaagaatc agt
//
LOCUS       DBERCW010000058        10223 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.058, whole genome shotgun sequence.
ACCESSION   DBERCW010000058 DBERCW010000000
VERSION     DBERCW010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.058"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(113..550)
                     /locus_tag="ACL72M_001961"
     CDS             complement(113..550)
                     /locus_tag="ACL72M_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGS0717026.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(635..3268)
                     /gene="polA"
                     /locus_tag="ACL72M_001962"
     CDS             complement(635..3268)
                     /gene="polA"
                     /locus_tag="ACL72M_001962"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGS0717027.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPDIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3524..4431
                     /locus_tag="ACL72M_001963"
                     /pseudo
     CDS             3524..4431
                     /locus_tag="ACL72M_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            4558..4839
                     /locus_tag="ACL72M_001964"
                     /pseudo
     CDS             4558..4839
                     /locus_tag="ACL72M_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4973..5941)
                     /locus_tag="ACL72M_001965"
     CDS             complement(4973..5941)
                     /locus_tag="ACL72M_001965"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS0717028.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVAVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(6086..6869)
                     /locus_tag="ACL72M_001966"
                     /pseudo
     CDS             complement(6086..6869)
                     /locus_tag="ACL72M_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
     gene            complement(6894..7391)
                     /locus_tag="ACL72M_001967"
     CDS             complement(6894..7391)
                     /locus_tag="ACL72M_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGS0717029.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(7464..8825)
                     /gene="radA"
                     /locus_tag="ACL72M_001968"
     CDS             complement(7464..8825)
                     /gene="radA"
                     /locus_tag="ACL72M_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGS0717030.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8839..9354)
                     /locus_tag="ACL72M_001969"
     CDS             complement(8839..9354)
                     /locus_tag="ACL72M_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0717031.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9356..9799)
                     /locus_tag="ACL72M_001970"
     CDS             complement(9356..9799)
                     /locus_tag="ACL72M_001970"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGS0717032.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
BASE COUNT         3160 a         2457 c         1830 g         2776 t
ORIGIN      
        1 caacctcaaa acggtgtttt gagcagcccg cggctagttt cctagtttgc tagtgtgctc
       61 tttgattttc attgagtata acacaaaagg tagcccatca gctacctttt tcttatgctt
      121 cctcaatcaa gcgagtatgt tctctcttga tacagcgatt catcacgata tcatcacatc
      181 caccatcacg caaaatctct ttcgcttcta aactttcaag tcctagctgt gcccaaaaaa
      241 tcttggcatc agctttgaga aaatcacgcg ccacatcggg cagaaattca ctgcgacgat
      301 aaacattgac aatatctaca ggaaaaggaa tttcagcgag gctagcataa gccttttcac
      361 ccaagatttc gccacctgcc gccttgggat tgactgggat gattttatag ccccgagcct
      421 gcatttcctt tgttactcga ttgctggttg tttcttcacg gtcagacaaa cccaccacag
      481 caagggtttt actcgttgcg agatactgac gaatcacgcc atcacttgga ttgataaatt
      541 cttgactcat agaaatcctc ctttttcatc agtatagcac attttgaaaa ggtttgcaga
      601 attatactac aaaaaaggag gactagcccc ctttttattt agcctcgtac caggttgccc
      661 cttcattctc atctgcgata agaggaacac tgagttgaat ggcttcttcc atggtttgtt
      721 tcaccaattt tttcatctct accaattcag atttaggcac ttcaaggacg atttcatcgt
      781 gcacttgtaa cagcatctta gtctgataac cacctgcaac caaggcttta tccagctgaa
      841 tcatggcaat cttgagaata tctgctgccg aaccctggat aggtgagttg atagcagttc
      901 gctccgcaaa accacgaata ttgaagttgc gcgaattgat atctggcaac tcacggcgac
      961 gcttaaagag ggtctctaca tagcccttat cacgcgcctc ccgcaccact tcatccatgt
     1021 agtttttaat atctggaaaa cgttcaaagt aggtatcaat gtaggctttg gcttccttac
     1081 gactaattcc caaattatta gacaagccaa agtctgaaat cccataaacc actccaaagt
     1141 taactgcctt ggcattgcga cggtcatttg cagtcacatt atcaggacgc tcaatgccaa
     1201 agacccgcat ggctgtcgaa gtatggatat ctgccccctc ttggaaggcc ttaatcaagt
     1261 gctcatcctt agaaatatgc gccaaaacgc gcaattcaat ctgtgaatag tcagagctga
     1321 gtagcacact atcctcccac tctggcacaa aagccttccg aatcaagcgc ccttgttcca
     1381 atcgggcagg aatattttgc aagtttggat ccacactaga caaacgcccg gtctgggtca
     1441 aatcctgcat atagcgagta tgaatctttc catcagccaa aatccagtcc tgcaagccaa
     1501 ttacataagt agattgaatc ttagcaattt gacggtaatc caggattttc ttaacaatcg
     1561 gagcaatagg agcgagacgc tccaacacat ccactgctgt cgaataacct gtcttggttt
     1621 tcttagtgta ttctagagga agtcccaatt tctcaaagag aagcacgccc aactgcttag
     1681 gcgagttgac attaaactcc tcaccagcca gctcgtaaat ctcttgagtc agtttttcaa
     1741 tgacaagctc attttcagcc tgcatctcaa gcaaggtctc tttcttgacc acaatcccag
     1801 caatttccat cttggcaaga acaaaagcca gaggttgctc catatcataa agaagctcta
     1861 attgcccatt ttcgctgagt ttttcaagta aaataggctc tgtttctacc aaaacagcaa
     1921 gtttacaagc taagtgttcc aagaatttct cacgttcagg aatggccttt ttaacaccct
     1981 taccgtagaa agtttcatca tcaaccaagt aagtctgacc ataaagacta gcgatggtcg
     2041 caatttcatt gtcctccaca gtcgaaagga ggtatttagc caaacggatg tcaaaagcag
     2101 gcgcctgcaa atccacacca aaacgttgca aaagaacttt aaccttctta aagtcataaa
     2161 ctctcagaga tgttttttct aagaaatcct tgaaaatcgg gtcttgcaac agctcaagct
     2221 tgtctgtggc atagagctta tcctcacaag accaggcaaa tccaaccaaa ttatccgtat
     2281 ggtaattctc accaaaaagc tcaaagtgga agatagactc ttcactcagc atatcttgac
     2341 tgatttggtc aacaatagta aaatccaaac ccttagccac atcagctgac gacacattta
     2401 aagcctgctt gagctgtttg aatcccatct catcgtaaaa tttcccaaga ttttcaacat
     2461 ctggaccact atagaccaag tcctctaaac caatcgcaat cggtgccttg gtatcaatgg
     2521 tcgctagtgt tttagacaaa aaggcctgtt ccttgtcatt gatgagattt tccttcatct
     2581 tagaagtctt cattccatca atattttcat aaatcccctc aagcgaacca tactccagca
     2641 agagcttaat acccgtcttt tcaccgactt tggtcacccc agggatatta tccgacttat
     2701 cacccatgag cgccttgaga tcgataaact gagctggtgt gaggcccatt tcttccatga
     2761 ggtaatctgg cgtaaaggcc tcaaactcag ccacaccttt cttggaaatt tcaaccaccg
     2821 tatgctcatc cgtcagctga atcaaatcct tgtccccact gacaatggta atatcaaaac
     2881 catcctgctc tgctagctta tccagcgtcc caatgatgtc atccgcctca tactgagcca
     2941 gctcatagtg acgaatcccc atatgatcca gcaactcacg aatgaaagga aattgctcac
     3001 gaaactcatc aggagtcttg gcccgaccac ccttatagtc cgcatacatc tctgtccgga
     3061 aggtcgtctt tcccgcatca aaagccacca aaatatgact cggctcaacc cgctccaaca
     3121 aatgactcaa catcaactga aaaccataaa tcgcattggt atgcaaacca gccgcattct
     3181 taaaacggtc caactgctga tacagcgcaa aaaacgcccg aaaagctaca gaagacccat
     3241 caatcaataa taattttttc ttatccatac acccattata aaggaaagaa tcaaaaaata
     3301 ccattgggaa gagctagagc aagtattttt caaacttttt ccgaataaat agatagagcc
     3361 agagaattta gtaaacctag atttaaaaat gtgctataat ataatatatt gaatctataa
     3421 tagtacacct tgactgctaa aatatttcta taaattaatt tgactttcct gatagagtta
     3481 ttcacatctt atttcaactc actatagaag gaggaatagg aggattctca gacatccggg
     3541 catcagccca actaatgatt tgattgctaa gaaaatattc agcaatccag aaatcacttg
     3601 tcaatttatt cgcgatatgc tggacttgcc agcaaaaaat gtgaccattt tggagggaag
     3661 cgatattcac gtattactct ccatgcctta ctcggtgcag gatttttata ccagtataga
     3721 cgtcttggcg gagttggata acggtactca agtaattatt gagattcaag tccatcatca
     3781 gaattttttc atcaatcact tgtggactta cctgtgcagt caggttaatc aaaatcttga
     3841 aaaaattcgt cagcgagaag gtgatactca ctagagctac aaacacatcg ctcctgttta
     3901 cgccattgct atcgtggata gtaattattt ctcagatgac ctggcttttc atagctttag
     3961 tatgcgcgaa gacacaacag gtgaggtatt ggcgattacc aacaatggac aggaaaacca
     4021 tctggttaag atggcattct tggaattaaa aaatacagag aaaccagcaa agacaaggtt
     4081 cgcaagccat ggttggagtt tttcggcaac aagcccttta cccagcaacc gcaacgagcc
     4141 attagccaag caaatcaact gctggactac aagagctggt ccgaggagga caggaaaatg
     4201 tttagtcaac tacatatgcg agaagaacaa gtcttgttag cacaggacta tgccttggaa
     4261 actgctaggg ctgaaggcct tgaacaagga ctagagcgtg ggaaagttga aggaagggca
     4321 gaaaggaaac tttttgcctt cctagacata gtacgccaag gtcttctgac ttctgaggtt
     4381 gccagccagc aattaggtat gtcagtatct gaatttgagg cactgttgta aaatggctcc
     4441 ataatatcca tagtgggtaa atcccctatg gatattatgg agcctatttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattagaaa gaatcatatg
     4561 gaacaattac attttatcac aaaattacta gacattaaag accctaatgt ccagatttta
     4621 aacatcatca ataaggatac acacaaggaa atcatcgcca aactggacta cgacgcccca
     4681 tcttgccctg agtgcggaaa ccaattgaag aaatatgact ttcaaaaacc ttctaaaatt
     4741 ccttatcttg aaacgactgg tatacctact agaattctcc ttagaaagcg tcgattcaag
     4801 tgctatcact gttcaaaaat gatggtcgct gaaacttctg atgacgtata gtcatatttc
     4861 ttctcttttt attatatcac agttttaaat ctagctttac tagattcacc gctactatcc
     4921 atttattcgg aaaaaagacg aaaaaacctg agaatcatct caggcttggt cattaaattt
     4981 ttttctcaat atcgaaaagt ggagaaagtg gtcgtttttc atgaatacgt acgatagcat
     5041 cccctaggag atgagcgatt gaaatctgct caatcttatc aatcaaacgc tcttctggca
     5101 gatagatggt atccaaaaca accaatttct taatagctga tttttggata ttgtccgtag
     5161 caggaccaga aagaactggg tgcgtacagc ttgcatagac tgcaacagca ccagcttccg
     5221 caagagcatc tgccgcatga caaatcgttc cagcggtatc aatcatatca tcaatcaaga
     5281 tacaagtctt gccttcaacc ttaccgatga tgttcataac ttcactagta ttcatcttat
     5341 caacgctacg acgtttatca ataatagcga tagatgtttt caaaaattct gccaacttac
     5401 gagcacgagt cacccctcca tggtccgggc tgacaaccac atagtcagaa ccaaccatac
     5461 cacgccgctc aaaataatct gcaattagag gagcacccat caaatgatcc acaggaatat
     5521 caaagaatcc ttgaatttgc gcagcatgca agtcgatggt caataaacga tccactccag
     5581 ctacttcaag catatttgcg acaagttttg aagtgattgg ctcacgcgct ctcgcctttc
     5641 tatcctgacg tgcataccca tagtaaggca tgacaacatt gacagactct gcactcgcac
     5701 gcttcaaagc atctaccata atcaaaattt caagcagatt gtcatttaca ggcgaactag
     5761 ttgattgtaa gataaagacg tgtttcccac ggattgattc ttcaatgttg acctgaatct
     5821 ctccatctga aaattggcga acacttgatt tccccaactc tatcccaatc tcctgcgcca
     5881 cacgttctgc caattcttta ttagaagaaa gggcaaacag ctttaaatca gaaaaagaca
     5941 tgatttcctc cggtatatat gtatcgcttg tgcttttcac aagattttcc atctaccatt
     6001 gtagcgcttt ttgcactatt tttcaatcaa aaataaaaga agggcaccat atttgtaccc
     6061 ttgcatcatt cttttgaaaa atattctagg tcatcaactc attgtgtttc tcaacaaagc
     6121 aataagcatg ataataacca tagagagcaa tagccgtaac cactggaatc gctaaaggca
     6181 actctgtttc caactccaca aaaggagagt taaacaataa gaccctgttt cttgccaacc
     6241 ttctgtcctt tataggctct gtaaagcaag taaacaccta ctacagctag acctgaaaaa
     6301 gtccagtgag aggcaattcc tgagatgata cgctctaaaa ttcgcgaaat agtaaagtca
     6361 aagccctctg gcaaatccgt acgaatataa ccaatatcct caatcatttg gaatcccaaa
     6421 ccggaggcaa ttccaagtaa aaacaaaaat tttaattttc gcacaggaat caaagccaaa
     6481 acaaaaacaa gtggcaataa tttcaagggt tcttctacca aaggagccac aatagcactt
     6541 tcaaaggcat ttaaaaatgg actatctggg aaaagaaccc ccagtaaatc atgtatataa
     6601 gtattagcaa aactagacaa ccagcctgaa aggaacatcc ctcccaataa agacagaatc
     6661 aaaaccttct ttggcaattc ccattttttc ccaatacgga agagaaaata aagagccgga
     6721 atcatgtaaa agagagctag aaagatagaa actcccatta gtccatattc cgcacctgac
     6781 ctcgaaccgt ccgtatagta gatggtttca tactgtaaac caatacatag caataaaata
     6841 aaaataaata aaatactgct tttcttcata cactttcttt ctaaatgaag tatttataat
     6901 tctacgactg tcatacttcc tgtatcaaca ttgtaaatag caccagagat aatgacatcg
     6961 tctggtatta ggggagactc gataagcagt tgcatatcct cgcgtacact ctcttctata
     7021 tcttggaagg gcaagaagtc ctggtctgac acatctacac ctaattcctc ttttaaatac
     7081 tcctgaaaag gttcattttc aaaggtctga gcaccacagt ctgtatggtg caataccaca
     7141 atctctcttg tccccatttg ttgctgggaa ataactagcg aacgaatcat gtcttcagtc
     7201 actcgaccac ctgcattccg caagatatga gcatccccaa gtgccaagcc cagagcttgc
     7261 gcaacgtgca aacgtgagtc catacaggtc acaatggcta ctctggtttt aggtttaagt
     7321 ggcagattta actgcccatg tagggcaaca taagcctgat tggcttgcat aaactgttca
     7381 aaatacgaca cgattccctc cttgaaaatt tgatagtcaa atatttctcc tatcttatca
     7441 tttttaagag aatttgtcac ggattatgca aagacctttt tcaagacttc ctgaatcgtt
     7501 gtcacgccaa tgacctgaat ttccttaggc agagtgattc ctgtcaagga attctgaggt
     7561 acataaatct tagtaaagcc cagtttagca gcttcgttga tgcgttgctc aatacgattc
     7621 acgcgccgaa tctctcctgt caagcccagt tctccgacaa aacattcctg aggattagtt
     7681 ggcttgtctt tgtagctcga agcaatagca actgcaacag ccaagtcaat ggcaggttca
     7741 tccaatttaa caccaccagc agatttgaga taggcatcct gattttgcaa gagaagccct
     7801 gcccgttttt ccaaaacagc cataatcaag ctagcacggt taaaatcaag tcctgtcgta
     7861 gtacgcttgg catttccaaa catggtcggt gttaccaaag cctgaacctc cgccaaaatc
     7921 ggacgcgtcc cttccatggt tacaacgatg gaggaaccag tcgccccatc caaacgctct
     7981 tctaggaaaa cttgactcgg attgagtacc tcaaccaagc cgcccgactg catctcaaaa
     8041 atcccaatct cattagtgga accaaaacga tttttgaccg ctctcaaaat acgaaaggtg
     8101 tggtgacgct ccccttcaaa gtaaagcacc gtatccacca tatgctccaa catacgaggc
     8161 ccagccaagg ttccttcttt ggtcacatga cctacgataa agatggcaat gttattggtc
     8221 ttggccaact gcatgagttc agcggtcact tcacgtacct gagaaacaga cccctgcacc
     8281 cctgaaatct caggagacat gatggtctgg atggaatcaa taatgagaaa gtctggctgg
     8341 atacgctcca cttctgcacg aacactctgc atattggtct ctgcatagag ataaaactca
     8401 ctatcaatat cacctaagcg ctctgcacgt agtttaatct gctgggcaga ctcctcccca
     8461 ctgacataga gaactgtccc cacttgggac aactgggttg agacttgtag gagaagagtt
     8521 gatttcccaa tcccaggatc cccaccgatg aggacgagac ttcctggtac cactccgcct
     8581 ccaagcacac ggttgaattc ctccatctcc gtcttggttc gattgacatt gatggaagtc
     8641 acctcagcta gtttcatggg cttggttttc tcacctgtca aggacacacg cgcattcttg
     8701 acctcggcaa cctcaacctc ttccacaaaa gaagaccaag acccacagtt ggggcaacgt
     8761 cccagatatt taggggaatt atacccacaa ttttgacata caaatgtcgc ttttttcttt
     8821 gcgatgacaa acctctttct atatctctaa ctcacactca atcacttggc aaaaatcaat
     8881 cttctcattt ggcacaaact ggcgcatgag cattcgatga gcaacaacta ccacagtctg
     8941 atgttctcga tacttagaca tacattctag aaaccgagac ttcatttccg tagctgtctc
     9001 atattgaata ggactattag gaagcaactc ccccttgttt tctaaaaaca gtcttctagc
     9061 tgtttcaaag ttttctattc ctgttttata gacctgccat tcatgtaata aaggctctac
     9121 tcttaaagga agacccgtag cacagaccac atacgaagcc gtttctaaag ctcttgtgac
     9181 tgcagaagat acgattattt cagctgacga gagtaaagga tttttgctca atttctggac
     9241 ttgctgccgt cccatctcag acaagggtgc caaatctatc ccaaatccta tataagaacg
     9301 ctcctctaac tcacggtaat ctggctcccc atgacgtaca aagataatct tcattctagt
     9361 gccctgtcga tccaaatcca ccagttcgaa cgccatcagc tgcatctcca tctgcaatta
     9421 agaaagtagc aaaaacagcc tggacaatac gttccccaac ttcaagaaca acctcttgat
     9481 ctgtgatatt cttcatctgc gcaaaaatat gcccttcatt tccaggattt ccataataat
     9541 ccccatcaat gaccccaact gagttaatta aaaccaagcc cttcttacga ggatttgaag
     9601 aacgatcata gaggtagaga acctcagtcg gctgcatata agccttaacc cctgtcggaa
     9661 ccaagacaat ctctcctggc gcaacaactg tacgcacagc aacctttaag tcgtaaccag
     9721 ccgcatgcgc tgtctcacgc ttgggcaata aattttcatc tgtaaaactc gaaaccaatt
     9781 caaaaccacg aattttcata attttctctt ttctattatc atttattcta gattattcta
     9841 tcttatttat tcggaaaaag cacgaaaaaa agagcacaca acaattatag gcgatacgat
     9901 aatttacact gtttcacaat acgttgaaat ttagagcttt aaagcgaggg caaagttgat
     9961 tttttacatc gttttacaga ggtttacgac acttttgccc cttttttgcc cctttgtttt
    10021 tcaaaaaaac ttcatcaaat cgcttgactt tcacggttta ccgtgatata atataatcaa
    10081 gataaggaaa ggaggtgagg aagttgaaca aagaagattg gcttaggtta ctggaaaagg
    10141 cgatagataa tatccctgaa acggtaactg ctatagcaag tctggtgact gcaataacgg
    10201 tcgcaaggca aaacaaaaag cgt
//
LOCUS       DBERCW010000059         9559 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.059, whole genome shotgun sequence.
ACCESSION   DBERCW010000059 DBERCW010000000
VERSION     DBERCW010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9559
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.059"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(200..1003)
                     /locus_tag="ACL72M_001971"
     CDS             complement(200..1003)
                     /locus_tag="ACL72M_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGS0717033.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1284..2039)
                     /locus_tag="ACL72M_001972"
     CDS             complement(1284..2039)
                     /locus_tag="ACL72M_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGS0717034.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCFSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPCFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2109..4760)
                     /locus_tag="ACL72M_001973"
     CDS             complement(2109..4760)
                     /locus_tag="ACL72M_001973"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGS0717035.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(4772..5734)
                     /locus_tag="ACL72M_001974"
     CDS             complement(4772..5734)
                     /locus_tag="ACL72M_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HGS0717036.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            complement(5736..6293)
                     /locus_tag="ACL72M_001975"
     CDS             complement(5736..6293)
                     /locus_tag="ACL72M_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS0717037.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(6280..6690)
                     /locus_tag="ACL72M_001976"
     CDS             complement(6280..6690)
                     /locus_tag="ACL72M_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HGS0717038.1"
                     /translation="MKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISER
                     TQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTY
                     FMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7142..7537)
                     /locus_tag="ACL72M_001977"
     CDS             complement(7142..7537)
                     /locus_tag="ACL72M_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS0717039.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7633..7887)
                     /locus_tag="ACL72M_001978"
     CDS             complement(7633..7887)
                     /locus_tag="ACL72M_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGS0717040.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7897..9231)
                     /locus_tag="ACL72M_001979"
     CDS             complement(7897..9231)
                     /locus_tag="ACL72M_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGS0717041.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9231..9464)
                     /locus_tag="ACL72M_001980"
     CDS             complement(9231..9464)
                     /locus_tag="ACL72M_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGS0717042.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
BASE COUNT         2748 a         2133 c         1763 g         2915 t
ORIGIN      
        1 aactttgaaa acttcaaaaa aacggatttt tatcgctctg aacatcaaaa aagaaaggac
       61 gaaatttgtc ctttctcgaa cttagctttt cttcaaccca ctacaattga caaagagcca
      121 aactttgatg atatacgttt tcttgtgaga atatttactt catttttgcc taaaattcaa
      181 tgtttactca gtatttggat tatgaaaaat caaggtctaa atctagatac attttttctg
      241 aagacaaatc attttgacca ccgagcaaga gattttcaaa aaaagctgtt aaaaactcag
      301 gacgtcgctg taaaatcttt gcattatcta ataccaaggc atcacgaaaa tatttggaat
      361 gttgctgaaa tggtgtatta tcaatatcaa aaccaaactc acgaagatac tgaatcaaaa
      421 agaccgttac tgtccgagtg tttccttcgc gaaatggatg aatctgccag attcctgaaa
      481 taaaatgctg gatttgttta accacatccg cctgagttag tgtcgcatat gcaacttgtt
      541 tttcctgatt aaaatcataa tctaaggtca tttgaatcat ggagtaatca gagtacacaa
      601 cactttcacc attcaaaaca ggttcattct ttgtgatatt ggtctgacga aattgcccca
      661 ccggaataga gggttcaaat atatcttgaa acaactcctt atgaatagca agtaaggtcg
      721 caggactaaa gctaaagcct cttcgagaca atagttctac aatacgtaga gaaaccaagt
      781 ctgcctcttc cgtacttgca tcaatagtat ggtgataagc cgttgcatcc tcataaacct
      841 gctcataagt cagttctccc cgggactgtt tctcagccaa agattccata tacgctgatg
      901 gcactagatt gtcaactttc tgcagaccaa aacctatccg ccataaatca cgcttcgctt
      961 cataagacaa gtttggattg tcaatgttgt aagttggttg catagaaata tcctttcaat
     1021 tgtttttctt cattaccagt aaatcacgaa attggttgga aactggctta aactataaaa
     1081 agtcctcaca ataggttcta tgatatatat atatatatac ttcatgtaaa taataaaaga
     1141 gttataatca gcactactga taaattcaat accgatttcg ccatcttaaa acttagtcaa
     1201 acgaataccg ttgatttcca gttcattaag tcgttgacct gtcaagactt ctcgttcctt
     1261 caactggaaa agttaagggg gaactaatac aaatcctcta cgcttctata ttcaatgatt
     1321 tcatttttga taatattctt tttaaactca aaatgtttta aaggattatc gattaacact
     1381 aactttggaa tatcatctag atttgtgacc aaggataaaa taaaatccga ttgaaactcc
     1441 ttgacttttt caaattcttt tgcagttaaa cgcacacgcc ccttagattt tcggatacct
     1501 tttacttcgg caaggtaaga atactcttgg acatctacct gaaagtcata tccatcacca
     1561 taaagacggg catcggttaa ctgtccacct tggaattttt cttctttatc aaaatgaagg
     1621 ataaaataat tctcagcctc cattcccgtt tcctgtagac gtttgaattt agttcgaact
     1681 attggttttt caacgatggt tatgcctgtt ttcttccctt cactggcaag taacatttta
     1741 actatttcag cataactatg aacatcttca tttccaaaca tcatatcaat taaatcttta
     1801 cgaaaacgat aaacttcagc tttctgccac caaccttttc gattattgtc aaaacaagga
     1861 tcaaataaat ccattctatt ttttacaact ccagttgttt cagcaattcc cagagaaacc
     1921 acatagcgat aaaactccga cttgctaaag cattgaaatt cttttataaa aagcttgtca
     1981 aacttggcaa gaccgtagcc aattaaattt aacaattcat aatgagggtg tttggacatc
     2041 actttctcca tcaatagata ttgatttcat tataccaaaa aacacggctc atcaccgtgt
     2101 ttctgtgttt atttcaccaa cttcttcatc tcatcaatac gtgctacggt cacatcatac
     2161 ttggcttggt agtcggcttg tttgtctttt tctttttgga caacttctgg tttagcgttg
     2221 gcgacgaagc gttcgttaga gagtttctta ccaaccatgt ccagttcttt ttgccattta
     2281 gcgagttctt tgtcgagacg agctagttct tcttcaacat tgaggagatc ggccagtggc
     2341 aagaagattt cggctcctgt aataacgctt gacatagcca gttcaggtgc agggatggtt
     2401 gatgcgattt ccaagtgttc tggatttgta aagcgtttga tatagttgac attgctgtta
     2461 aagaaggctt ccaagtcact atcgcttgtc ttaacaagga tggtgatagg cttgcttggt
     2521 gctacattta cttccgcacg cgcattccga acagcacgaa ttaagtcttt gagactttcc
     2581 acaccagtgt gagccgcaag gtcttcaaag gctagattaa cagttgggta tgcagctgtc
     2641 acgatagaac cttctgagat ttgtccaaag atttcctctg tcacgaatgg catgattggg
     2701 tgaaggagac gaaggatctt gtccaaagtg tatagtagaa cagaacgtgt gatgactttc
     2761 tcttcttcgt tatcgctata aaggacttcc ttggtcaact caacatacca gttggcaaat
     2821 tcttcccaaa tgaagttgta aaggatatga ccagccacac caaactcgaa cttatcaaag
     2881 ttttcagtaa cttttgcaat ggtttcgttg agattgtgga gaatccagcg gtccgtcaca
     2941 ttaccagcct cacctgttgc aacttttgtg acattgtcat gcgccacatc cagcgtcaaa
     3001 cctccattgt tcatgaggat atagcgagaa atgttccaaa tcttgttaat aaagttccat
     3061 gaagcatcca ttttctcata agagaaacgc acgtcttgtc ctggcgcaga accgtttgaa
     3121 aggaaccatc gaagggcatc ggcaccgtat ttctcgataa catccattgg gtcaatcccg
     3181 ttaccgagag acttagacat cttgcgtcct tgctcgtcac gaatgagacc gtggataagg
     3241 acgttttgga atggttgacg gcctgtgaat tccaatgact ggaagatcat acgagacacc
     3301 cagaagaaga tgatgtcgta acctgttacc aaggttgaag ttgggaaata acgtttaaag
     3361 tcttctgagt cgacttcagg ccagcccatg gttgaaaatg gccagagggc agaactgaac
     3421 caagtatcca agacgtcttc gtcctgagtc catccgtcac cttctggagc ttcttcgccg
     3481 acatacattt caccatcagc attgtaccag gcagggattt ggtgacccca ccaaagctga
     3541 cgagagataa cccagtcgtg gacattttcc atccattgaa ggaaggtatc gttgaaacga
     3601 ggtgggtaga attcgacctt gtcctctgtg tcttggttgg caatggcgtt cttagccaat
     3661 tggtccatct tgacgaacca ttgagtagac aagcgtggct caactacgac acctgtccgt
     3721 tctgagtgac cgactgaatg gacacgtttt tcgattttga caagggcacc gatttcttcc
     3781 aacttagcaa cgactgcctt acgagcttca aaacgatcca tgcctgaaaa ttcaaaggca
     3841 agctcattca tagttccgtc gtcgttcatg acgttgactt gtggcaagtt atgacgttgg
     3901 ccaaccaaga agtcatttgg atcgtgggca ggtgtgattt tcacgacacc agtaccaaac
     3961 tcaggatctg cgtgctcatc tccaacgatt gggatgagtt tattagcgat tggaaggatg
     4021 acgtttttac caatcaagtc cttgtagcgc gggtcttctg gattaaccgc aaccgcaacg
     4081 tccccaaaca tagtctcagg acgagttgta gcaacttcaa gggcgcgtga accatcttcc
     4141 agcatgtaat tcatgtggta gaaggcacct tctacatcct tgtgaatcac ctcaatatca
     4201 gaaagggctg tgcgagctgc tgggtcccag ttgatgataa actcaccacg atagatccag
     4261 cctttcttgt aaaggtccac aaagacctta cgaacagctt ttgacaaacc ttcgtcaaga
     4321 gtgaaacgct cacgagaata gtctacagaa agccccatct tgccccattg ttccttgatg
     4381 gtagtggcat attcgtcttt ccattcccag accttcgtca agaaagactc acgacctagg
     4441 tcataacgcg taataccctc accacgtaag cgctcctcaa ccttagcctg agtcgcaata
     4501 ccagcgtggt ccatacctgg aagccaaagg gtatcaaagc cctgcatgcg tttttgacgg
     4561 atgatgatat cctgcaaagt cgtatcccaa gcgtgaccaa ggtgaagttt cccagttacg
     4621 tttggtggtg gaatcacgat tgaataaggc ttagcctttt gatcgcctga aggcttgaaa
     4681 acatccgcat caagccattt ttggtaacga ccagcctcaa cctcggctgg attgtattta
     4741 gatgaaagtt ctttagacat gtgtgttctc cttaattact tttattgaca attttaacca
     4801 aaccaatttt tgaaagttca atataaatct cttcaatttc agcaaatgct gcaagtggtg
     4861 acatagtata atttccagga ttatatttaa gatcatactt gcttatcttt gaaatataat
     4921 acctagagtg tttcaatttt aatgattcca actttgattt aatatctact aatgtattat
     4981 ggtttaactt taaaaacaac ttattataat taccatagag ctctgtaaga gcattaaagt
     5041 attctttcac tagagctata gcgtcaatct tagatgtttc ttggtttagt tttatcaact
     5101 cccctttcaa ttttttccat ttaaagttgg aatttaaaag ataatctaaa tcaatataga
     5161 aatctattat aacagtctca tcatctgggc taacagcttt tacctcattt attggtaagt
     5221 cagtatgttg cgaataattt ctcaaagaat ggcaaaatcg ataagcaaaa ttggtatcat
     5281 actgatagct tgcaaaacca tgtatacaat caaactcctc actatctttg gaatattttt
     5341 gtttaatttg gttttcgtta aaatcgacaa acaattttcc actggataat aaatgaatca
     5401 tgaaacgatt tacatctgcc tcttcaattt ctaattcctt tgactcaagt ttatttttaa
     5461 tacttaaaaa atccgagaca tctgaaataa acaattcgaa catattcttg attttttgaa
     5521 aattcttttg aatctcaaaa atttggtccg agactgacat tatttccttg gttggttcaa
     5581 tatcagagat gacaatacgt ttttcattgt tgttaatttc taaataagct aatcgctcga
     5641 taatatcact atcatttaat tcagcatact caacatcaat ttggcgtaac tgcttctcag
     5701 atagagagct tacttcctct tttacatcgc tcatcttatt cctcccactc gctcttcagc
     5761 aagccatata tcagactgtc acagcggttt ccttgaacat cctttcggtc tcttatgcga
     5821 gcttcgaggg taaagccaag cttttccgcg actcgttgac tttgaaggtt atatccaaag
     5881 caagttagtt caatcttgtg aagacccaaa tctttaaagg ctaagtcaat caaggcacgc
     5941 gcagcttctg gcacataacc tcgcccccaa tagtctgagt gtaaggtata gccgatttcc
     6001 atcacatcat cttcatggcg atggttgaaa tagatagagc caacgatctt atccgttcct
     6061 ttgacgacaa tcccgtagcc tgctgggaga ttttcctttt gattacgctc cggaagaatg
     6121 tgctccagat aataaatctc atcttccaag gtcttgactg gaggaaaacc tgctggatag
     6181 gcgacctctg gcaaactagc atagtcaaag atatcctcag catccgccac agtacggact
     6241 cgtaaaacga gacgttctgt ttcgatttta tctggcagct cagttcttgc catccttctt
     6301 cctcgctttt ttgatgaaac tgcccttcat atctacacgc ttgtccagat agcgataaac
     6361 gcgctgatat ccatctccca tgaaataggt tggggcaaac agttgatttt taaaatgtcc
     6421 cttttcatcc aggagttctg gggcaacaag tcgctcaaga atcttggcaa agatgtggca
     6481 aataccgtct tcctcaacaa tcctatctac ccgacaatct aaaacaagtg gacaggcgtc
     6541 taaaatagga gtctgagttc gttcagaaat ttcataatgc actcccaaac gttccaattt
     6601 ctcctgatga ctgataaaac cagcctgctc catcgcaagc atagaagttt catcagaaat
     6661 attcacagta aatttttgat actgtttgat ctactctgcg gcattctctc tcgcaacgac
     6721 tccaatcaca acccaatctc ctagactata agaggaacta caggtcgtga tgttatagcc
     6781 aaaattctaa tcttgatatc ctaaaataaa aacaggaaaa ccataatata gtttacttgt
     6841 gttaaaagat tgcttcataa caaccccctt tgactaagac gtaaaagaaa agccctgcca
     6901 tctacatgac agggacgaat gtgtttatcc gcggtaccac ccaatttcgg gcagttgccc
     6961 gcaactctcg tctttaaagc aaaaagacac ttttatttca atttttcatc cattagcaac
     7021 cagttttgac acatttgtgg acttctcagc gccgccactt tctgtaaaat gtgggattca
     7081 aaacacctct aatggctcta ttgtagcaag attttttcgg aaatgcaagg ctcaagaaaa
     7141 attacttgaa cttgatgcca ttttctttca atttcttgat ggtagctggg ccgattcctt
     7201 tcaagtcaag gagttctttt tcagtccagt ttttgaaatc tgaagcagac ttgattcctt
     7261 catcatagaa agtcttggca cgatcaagtg gaagtccacc caaatttgct gcaaaatctt
     7321 ctacagaatt agctactttt tgagcttgct ctttggtagc ttctactgct tgttcaactt
     7381 ttttagaaac agccttacca gctgcgcttg ctgactgttc tgcacgcttc acgacttttt
     7441 ttgtctcatc tacaacctta gtcacagtac ttgaaaaggc acctgcgcga cggaggccat
     7501 ttcgtaattg ttttttacga ttgagtttct ttgacatgat aaaatccttt caataaaaaa
     7561 tccctgctct gacaaggatt taacataaac attctatcaa gattttagtg aaaaatcaag
     7621 aatctttctc gtttaataat ttcgctcacc aaacaagcct tctggcaaat catggaatcc
     7681 cttgcctact ttgaagtttt caaacttacc aagcaagaac tgataagcat ccaagcgact
     7741 ctcgtagcga atcatggcat ctttggcacg ctcgtcctgg tcttcttcgt aaactttttg
     7801 gctttccttg tgcgccatgt cgttaatcat gatttgggta ttgacccaag cttcaaattc
     7861 cttcataaat tcttgttcgt aactcatttt ttctccttat tctaatccac ggaaatagtc
     7921 cgtatcaatc tcacggtagg gctggatatc ctgaacgtat tccagtacac cttggaattc
     7981 tccgttttca tcgtgtactg cagcataggt gatgtggaca aacttgcctc gcgactcaga
     8041 cttgaaccac atttcatact tgtccttggt cccctcacga agtcccttca tgatagcctt
     8101 gaccttgtcc aaatacttag gcggatgaca gagttcgaca ttgcgcccga cttgggacgg
     8161 cgtccgtttg aaaatcatct catcagctgg cgtattgtca ttgtaatact ggaaaatatc
     8221 ttctttattg acaaaggtaa tctccatagg gagatgattg aggatgagat tggcctgctc
     8281 gactgaaaga tagccattac caaaagcctg ttgactatgg cggtccagca cagcttcctt
     8341 ttccttaggg gtaaaggtaa tggtaaaatg gccttctggc gtatctatga cttgttgaac
     8401 ttgaccttct gccgtatcta gctgtacagg ctcctctgca atcttttcct caataaagct
     8461 ctgtcgttct ggcacccatt tctctgacgg acggatgatg gcatagccat aggcatcgct
     8521 ctcctccgca atctgaagcc agtcatcctg agtaaaagac tcaaggagaa tcatgaggag
     8581 gatggactct tccttgaaaa tcatactttc aaactctgtc gcaaaagctt caaaagcttc
     8641 ctttacactg ctaattgaca cttctggtag tgacttggct gtcgttagag ctgtttgaaa
     8701 gagttcccta atctgatcat ccactcccca cataactttg ggaggtgaat cgtgtccata
     8761 gcgctccatg ataggaaaga agagttcttc cttacgttgg taatggatgt caaattgacc
     8821 cacaagtccc atctgacgca ccaaaccctt acgcatctcc gccagcattt cctcgtcttc
     8881 catagactca taggtatcta acaatctacg aatgcgaatc aaggccgcac ggagagccag
     8941 attttcttct ttgaagacac gaactgggtg acctggatgc tcagtatctg aaacttcgac
     9001 acctttgata gcatttttaa aaagattggc atggacatca cagagttcca taacatcttc
     9061 aaaggtgaca cctgagtctg agttcatcag ctcgtgctcc ataagggaaa tctcaatggc
     9121 tgagacaccc gcaaaggtcg catcaaaacg ctcctgaacc gactcaggag aggcgccatt
     9181 atgcaattct aataaaatat cccgtaggac atgaatccgt tcatctgcca ttagtctaat
     9241 ccaatcactt cgtagccatt cgcttccagt gtgcgtacaa tcttgtccat aggagttcct
     9301 gctagcttag aaccttgttt aagtgatact ttacgaccaa ctgtattgcg cattaaggga
     9361 ttggcaaggg gtttaaaacc caactccact agaatttcca agacttctgg atgcttgtcc
     9421 accacttctg caacaggaat tgacacatcg atgatattgt ccatgacgac ctccattgta
     9481 tgttctaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggttgctcaa
     9541 aacagtgctt tgaggttgt
//
LOCUS       DBERCW010000060         8374 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.060, whole genome shotgun sequence.
ACCESSION   DBERCW010000060 DBERCW010000000
VERSION     DBERCW010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8374
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.060"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(631..939)
                     /locus_tag="ACL72M_001981"
     CDS             complement(631..939)
                     /locus_tag="ACL72M_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0717043.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(936..1244)
                     /locus_tag="ACL72M_001982"
     CDS             complement(936..1244)
                     /locus_tag="ACL72M_001982"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0717044.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1249..2544)
                     /locus_tag="ACL72M_001983"
     CDS             complement(1249..2544)
                     /locus_tag="ACL72M_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0717045.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVNRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2562..3971)
                     /locus_tag="ACL72M_001984"
     CDS             complement(2562..3971)
                     /locus_tag="ACL72M_001984"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS0717046.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4129..4857
                     /locus_tag="ACL72M_001985"
     CDS             4129..4857
                     /locus_tag="ACL72M_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0717047.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5317..5511
                     /locus_tag="ACL72M_001986"
     CDS             5317..5511
                     /locus_tag="ACL72M_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0717048.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5633..5799)
                     /locus_tag="ACL72M_001987"
                     /pseudo
     CDS             complement(5633..5799)
                     /locus_tag="ACL72M_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5877..7187)
                     /locus_tag="ACL72M_001988"
     CDS             complement(5877..7187)
                     /locus_tag="ACL72M_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGS0717049.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7424..8296
                     /gene="nadC"
                     /locus_tag="ACL72M_001989"
     CDS             7424..8296
                     /gene="nadC"
                     /locus_tag="ACL72M_001989"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGS0717050.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2604 a         1466 c         1588 g         2716 t
ORIGIN      
        1 tcctgataga gttgttcaca tcttatttca attcactata gtttaattta agagtagtat
       61 ttactaaggc ccaattaaaa tcaaagagca aactagaaaa cgagtgccat tcagctcaaa
      121 acactgattt gagattgcag ataagactag ccccctcatt aacagattta cgataaaacg
      181 atgacaaggt gtgttgcttt ttgatttcta aagagtataa tgatagatct ctataaaata
      241 agtgcgaagg aaatgagctt ttatagtcct ttcgttttaa aatactatct cagatattct
      301 tatatcgaca agaagttttt gagtcattcc ctcatcatac atattaaata aatagtggct
      361 cattcaattt ttcactagaa taataagcta gtatagtaaa ctgaaataag atataaacaa
      421 ataaattgga gcttaacatc catttccagc aattttttag aaactacagt ggactattct
      481 agattcaaca tattataaaa actagagtaa aagaaaagga ttggatcttg tgtaatgcag
      541 gatccaatcc tttcaatcat tttgtccaac ttttggaggt tcctacaatg tagtcgtcat
      601 taataaagac agatgggaat gacagtgttc ctatttattt tgatagagat cgatgaattc
      661 tttagatagc aactgaataa tctctgttga agccatttgg tcttctgcat gcataaatag
      721 caaggagaat cctatttttt ctccagtagc ttctttttgt atgagattag agtgaatctt
      781 gtgcgcttct actaaggagt cttccgcttc ttcaacttta attttcgctt cttttaaatt
      841 tcctgcctta gctagttgga tggcttcaat aaaggatgat ttggctgctc cactattggc
      901 aatgagctga aaacagatat attccatttc ttctgtcatc ttatttctcc tatccatgca
      961 agtgcttgtt ccagaacttt tgctccattc atcattccgt aatcccgcat atcaatggta
     1021 tctacaggga tatttcctgc aatttctttc acagcaagta actcataacg aatttgtggc
     1081 ccaattagaa tgacatctgc ttcatggata ttctttttag cttctgtcat tgattttgct
     1141 tggatagaga tttcaatccc acgttcagtc gcactttgtt gcattttttt aacaagcata
     1201 cttgtcgaca ttcccgcatt acatactaat aaaatttgtt tcataatctt aaccttccat
     1261 ttcttgttca acaactttgt cattaacttt gataaatgga atgtatagaa gaactccaag
     1321 tgcaaagatg atgaattgaa ctagaactgc tctcacgtcc cctgctgttg ctaaccatgc
     1381 atttaagaat actggtgtag tccaaggaac ttgtataaat gcaggactca tgaatcctgt
     1441 aactgttgct aagtagctga ttaaaatacc aaggactgga actgtgataa atggaatagc
     1501 taatgaaatg ttataaacga ttgggtaacc gaataatact ggttcattga tattgaagat
     1561 accaggtcca aaagataatt tagccacgtt tttagagaca gcattgcgac tcactaagaa
     1621 tgttgctatt aataaacata atgtagatcc actaccaccc attaaagcga atgtttgtat
     1681 ttgtgatagg ttgatgatgt gtggaatggc ttgtccatta tttgctgcag tgatgttttc
     1741 agtaatgtta attaatagta atggttctag gatggcactg taaataactg cttggtgaat
     1801 accaaatagc cataacatat ttcctaaaga gtaaataata atgaccccga ttaagcttgt
     1861 accaatatga cgaattggtt cttgaataaa gattgtaatg attgagatta agttcattcc
     1921 agttatattg aataataatg ctgaaacaac cccaaataag gagatgacgg tcatgactgg
     1981 aagtaatacg ctaaatgatc tattaacagc tggtggaata ttttcaccaa ggttcatttg
     2041 taaagcttta acatttgata attcaatgaa taattctgtt gcaataatcg ctacgataac
     2101 cccggcgaac attgcgcctg tacctgtgtt gttgaatgaa agaacacctg aaatgtttac
     2161 agcatctttt gctccgtcag gaactacaga aactgtattt ggcatcatca caattaaaga
     2221 aactaatgat agcattgatg ctgctaacgg gttttcgaaa tctctgtttt tagctaagaa
     2281 ataaccaacc attacagcaa taatcatacc tgaaatactt aaagtaccgt ttgcaattgt
     2341 tattccccaa tattggaatc ttgttaatgt atccccttgg aaaatccact taaataccgt
     2401 gttgttcaaa agaacgatta aacctgccaa aatatataat ggcattactg ttacgaatgc
     2461 atctcttagg gtttttaaat gaatttggtt ccctagttta ccagcaaagg tggcaaattg
     2521 gtctataaat tttgagtttt tcatatgaat atctcctctc tttactcctc aatttctact
     2581 tcaaaaccgt tattgtcact tactttgcga taccatcttc ctgagctctt gatggttctc
     2641 ttttgcgttt ctaaatcaac ggagataaat ccgtaacgat tcttatatgc attattccaa
     2701 gaccagcaat caaatgcggt ccaagcgtgg tatccaaaac agtgacttcc ctcttcaatg
     2761 gctttatgta gccatcttaa atgttcttca taaaattcaa tacgatacac gtcatcgata
     2821 actccatttt catcgataaa ccgtgcttcg ttttcaacac ccattccgtt ttcactgata
     2881 aaccatggga tattaccata ttcttccttc acaatcatag caatatcata aatggatttc
     2941 ggaaaaattt cccaaccacg atatggattc atgcgacgct ccggccattc atactctttg
     3001 aagtattggt ctggcatcca gggcgtctga tattcctcag gatttgcttg tgcttgaaca
     3061 cgttttggat ggtagtagtt tactccaaga aaatcaaccg tatttgattt catcagttga
     3121 agctcttttt cggtatgact ccataacacg ccatctctct ctagctgttt taccaatctt
     3181 tctgggaaag ttcctttaac agctggattc aagaagactt tgttaaagaa gtcatctgta
     3241 aatcgacttg cttctaagtc ttctggagaa ttacttcttg gataagcagg tgtcaagttt
     3301 aaaataatcc caatctttcc atcaagttct aatgagcgat atagttgaat cacttttgca
     3361 ctagcaaggt ttagattata gatgacttgt acggcctctt ttccctttcc ttttagattt
     3421 ggataatgga aagcatataa gtatcctgct tctggaatga ccattggctc attgaaagtt
     3481 gtccagtaat gaaccttatc tccaaagcat gtgaaagcag tcttggcaaa cttcacgaat
     3541 aactccacta catgtttgct ttcccaacca ccgtattttt gaagaagttc cactggtaaa
     3601 tcaaaatgat gtaaattcat cacaagatcc atctggttct ttttagcttc ttcaatgatg
     3661 gcattgtaga aagcaatacc ttttggatca ggctcacctg tctctaaatt cttgatgagt
     3721 cgactccatt ggatggaagt gcggaaagaa ttaactccaa tttccttcat caagtggaaa
     3781 tcttcggtgt aagtatgaaa aaagttactg gctacaagag gtccgacatt atcgaaaaaa
     3841 tcttctggat gcgttttgaa ccagtagtcc atcacatttt catgtacttt tccatattga
     3901 ccttctgtct gaggtccgct agaagctgct ccccaccaaa acagattagg aaatactaac
     3961 ttttttttca tgctcaacct cctttctatt attctataca taaagtatag cataatttta
     4021 aaatttgtct agacattttt aaaaattgtt gatacatatc ttgtgtttgc ctcatttctt
     4081 gaactttgtt atactactat tagaatatta tagagagaac cagattaaat gagtacaaaa
     4141 tatttattta tttacaatga gattcgtgaa aagattcttt gtaataaata taccatgaac
     4201 gaacaattac ctgatgaaat gacattagct aaacagtttg cctgtagtcg aatgacgatc
     4261 aaaaaagctt tagacttgtt agtttctgag ggcttaattt ttagaaaacg tgggcaggga
     4321 acctttgttc tctctcgtgg cagctcaaaa agaaaattaa tcgttccaga aagagatatc
     4381 cggggactga caaaaatatc tgaagatgct cattctacaa ttgactcgag gattattcac
     4441 ttcaaattag aatttgcaaa tgaattttta gcagaaaaac tacaggtcgc tttgcagagt
     4501 ccagtttata atatttaccg cctgcgtatt attgacggta aaccttatgt tctggaacaa
     4561 acttatatga gtaccgatgt tattccaggt attactgaag atattttaca aaaatcgatt
     4621 tacaattaca ttgaaggaaa gttaggattg catattgcca gtgctacaaa aatcttacga
     4681 gcttcttcta gttcagaaaa tgagcaacat tacttgcagc tccttccaac ggaaccggta
     4741 tttgaagtag aacaagtggc ttatttggat aacggaactc cgtttgagta ctcgattagt
     4801 cgtcatcgct atgatttatt tgaatttaat tcttttgcat tacgacattc ctcctaggag
     4861 aaaatgtgaa aatgaagcca atcttttaca gactctagtt taagaaaaat ttaaaacagg
     4921 gcaagaaggt cccatctatg cttaaatggt ttctcttttc taaataagat ggctttaaaa
     4981 gagtgatcgt tttatccatc atgttgaaaa atatcttcgt atagcttata gagtaggtac
     5041 tgaaattgtt cacctgatct acttcttata gttatttagt tttaaatagt gtttcaaata
     5101 ttcttacact gacgagaagt ttttgagtct tttcttgtaa cacatatagt atactgaggt
     5161 tagaatagta gactgtgact tctaacaaat tgctagaaat gaatttcaat ctcccaattt
     5221 atttgttcaa atattgtttt aatatattga ataaattctg aatcataatc atttaaaaaa
     5281 attttatttt tttatttttc attacgaata atatagatga aggggaaaga gtatgaaaac
     5341 agaactgttt cttttgctat tagttcaaaa ggagaaaaaa tgaaagtaga aaatatttcg
     5401 tatagggtgg atcatcgtat attgtttgat aatatttctt ttgatacttc gagttcaggc
     5461 gtgacattaa ttactggtaa aaatggtaca ggaaagtcaa ctttactata gtagattgaa
     5521 actagaatag tacacatcta cttctaaaat attgttagaa atcgatttga ctatcctgat
     5581 ctatttgtcc tgttcttatt tcatttcact atatctcaaa ttgagtatga cgaagtgcgc
     5641 tcccatgtcc tgggaacgca ctttcttcat atttttcata ttcttgaatc catcgataaa
     5701 gactattggg atgaattttt aaagttgaac taatcatttt tacaggatga gatttacagc
     5761 agagagtttg aaggctttat caaaggtttt tcttggcata atgacttttc ctcgtttcca
     5821 cttaattttg tgtctacttt attataccaa gtccaccctt aagttagata ataaatctaa
     5881 cttaaggaag ctagaaggat gagaatccag gtggtcaaga gtcccaaact taagctgatg
     5941 gggacaccca gaataatttg ctttttgaag gcaaggccac gttcctctat attgggaagt
     6001 gagagttgaa tgagagaacc agctgatgaa aagggtgaga tattagtaga tagagcgcca
     6061 ataacggtgg ctgttgtgag taagtgaata tcaatctgag gattttgagc actgatgata
     6121 gcaatgatgg gaaagagggc tggagctaca acggataggg tggaactaaa gagtgacatc
     6181 actccggcta tcacacaaaa gaacagaggt aaccagaaat gaggaatggt tgttgtcatg
     6241 aggtgcccta tcagtgtgac taaacctgac ttgaccgcta gagacattag taagctcatg
     6301 ccgcagagca tgataattgt agcccaggga accttagcta aaatggcttc ttgcttccct
     6361 aatttgagcc ttaaggcgag gcagaccatg agtattgaga caaagccaat atcaaatgtt
     6421 ttttgataag tagctatcca ggcgatgttt gggaaaatga gatgcaacaa gggaaaaagc
     6481 caaaccaaaa ccatgctgct gatcatgagc aaggtggttt gtctttgaac cttgctgagg
     6541 agtggtggtt ggtcaatagt caaggatgag tttgttcttc ccttactata gtgactgtaa
     6601 caggataata aaagcaagac gatgagtggg tagataatgc tgacgataaa gatatgattg
     6661 ccaagtgaaa aagcttgctc ttcccatccc atttgcttaa acaggccttg aaagacaatg
     6721 cctgagctac tggttatcaa attagcccct cctgaagctc cccaattgac ggcttgagct
     6781 ccaatcaaag ggtgtttgtc cgctttttga cagagggtaa tcgctagagg acagcaaacg
     6841 gccatagtag tgaaaaatcc agcacctaaa gcagacaaaa gggttgccat caggtataaa
     6901 atcatgtaga gggcgttagg gtgggtgcgt gtgcggtaga gaatgtgttg agccaaaaca
     6961 tcaagagtac cgttagttgt tgcaacgtta taaaagagag agacgctaaa aatggtaaaa
     7021 aagagtgagg ttggccaaaa atgaagaagt tctttggggc ttaatcccat gagagtggtt
     7081 gcgatgaggt aagaaaaagc aatagccagc aggccaatat tgattttggt gcggtaacca
     7141 attccaatgg ctagagcaat ggcgctaatc attattaaat gaatcattga attgtccttt
     7201 cagttagaat atggaaatag gttggcaatt ttggcgctca aaagaccacc tgtttcctat
     7261 tggtacttga ctattataca caaaaaaaat acaattgtct tgacaattgt attgacactt
     7321 gttagaatta aaaatgaggt attcaggctt gtgatttcct atggaagtta atagtaattg
     7381 cctctagtgc ttacaagtga tattaaaaat agaggactta gtgatgtcaa tcatttcaac
     7441 tgatttaacc ccttttcaaa tagatgatac attgaaagca gccttgcgag aagatgttca
     7501 ttccgaagat tacagtacca atgccatttt tgatcatcat ggccaagcca aggtgtcgct
     7561 ttttgccaag gaagctggtg ttttagcggg actaaccgtt tttcaaaggg tttttaccct
     7621 atttgatgcc gaggtgacct tccagaatcc tcatcaattt aaggatgggg atcgtttgac
     7681 tagtggcgat ttggttttag aaatcatagg ctcggtgaga agtctcttaa catgtgaacg
     7741 cgttgccttg aattttttac aacatttatc agggattgct tcgatgacag ctgcttatgt
     7801 agaagcctta ggcgatgatt gcattaaggt atttgatact cgaaaaacta ctcctaattt
     7861 acgtcttttt gagaaatatg ccgtgagagt tggcggtggc tataatcatc gctttaattt
     7921 atcagatgct atcatgctaa aagacaatca cattgcggca gtaggtagtg ttcagaaggc
     7981 aattgctcaa gcgcgtgcct atgccccttt tgtgaaaatg gtcgaggtgg aagtggaaag
     8041 ccttgctgct gccgaagaag ctgcggcggc gggtgctgat attatcatgt tggataatat
     8101 gtcattggaa cagattgaac aggccattac cctaattgca ggacgttctc ggattgaatg
     8161 ttctggaaat attgatatga ccactattag ccgttttcgt ggtttagcga ttgattacgt
     8221 ctccagtggt agtttaaccc atagtgctaa gagtcttgat ttttccatga agggtttaac
     8281 ctaccttgat gtctaagttg taaaataaac taacttttta aaggatgtct ttcctctaga
     8341 acgagtttta tgtcagatag tttaaacgcc tctt
//
LOCUS       DBERCW010000061         6915 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.061, whole genome shotgun sequence.
ACCESSION   DBERCW010000061 DBERCW010000000
VERSION     DBERCW010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.061"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(112..387)
                     /locus_tag="ACL72M_001990"
     CDS             complement(112..387)
                     /locus_tag="ACL72M_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGS0717051.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="ACL72M_001991"
     CDS             complement(494..1333)
                     /locus_tag="ACL72M_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0717052.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="ACL72M_001992"
     CDS             1475..2323
                     /locus_tag="ACL72M_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS0717053.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="ACL72M_001993"
     CDS             complement(2416..3333)
                     /locus_tag="ACL72M_001993"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGS0717054.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3812..3960
                     /locus_tag="ACL72M_001994"
                     /pseudo
     CDS             3812..3960
                     /locus_tag="ACL72M_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="ACL72M_001995"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="ACL72M_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGS0717055.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="ACL72M_001996"
     CDS             complement(4596..4940)
                     /locus_tag="ACL72M_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGS0717056.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="ACL72M_001997"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="ACL72M_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGS0717057.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5452..6156)
                     /locus_tag="ACL72M_001998"
     CDS             complement(5452..6156)
                     /locus_tag="ACL72M_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGS0717058.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6558..6857
                     /locus_tag="ACL72M_001999"
     CDS             6558..6857
                     /locus_tag="ACL72M_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGS0717059.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2177 a         1405 c         1151 g         2182 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccgcctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggcaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccaaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaattg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg gtatcaaaat aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgaa cctttttatt ttgcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcactcctca gctcgccatc ttcggctctc
     4921 tcaaagactg cctgtatcat gtgttctcct taaaattaag cgttgattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa ccactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa cgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacga
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatga
     5461 agctttttct tttacttttt tctgccaaga ggcaaaaagc atgctgaggt aaaaaacgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaag caggctaaca aatatgaatc cttcacgcaa
     5641 aaaaggagtg tgcttggttc ggaaataatc tccaaaagcc agcatggtcc gtttgatatt
     5701 ccctgtcata aaagcgttat tataggcaat acccgacact tctccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggcggcac tagatagata ttatccacag tttgcggcac
     5821 aaaagcaata atgattgata agattgccaa gggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccatcataa acgctagcaa
     5941 ggtgagaacc ttgtccctaa catccgaaac attattttta attaattcta ctgaaagaaa
     6001 gacaacattt ccagtttgtc cagctacaag ggtattcccg cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa acgtcaaaaa aagtgctaac cttttagact gacgtgatat
     6121 ttttcttata ggtaataacc tcattttacc tcccattgta ttttctctta gaaatattgt
     6181 accattttct ttctaaaaaa tcgtaggcta ccatttagat tttactatta gcataaaaat
     6241 aataatagac aactatttat ccaaaaatag atagatgtaa catgtttgca aacaaagcat
     6301 acgaaccttt agtaaaatca tttccatgaa actagaatag agccctctta gcaaaaatca
     6361 ttattttaat ttatttctaa tcactccttg acataaataa ctctcaccaa taaaagacta
     6421 tgtcttaaaa aaatggtata ataaaatcaa tacttgggct tgatggctat gctactaata
     6481 acaattagga gagaaaatca ggcacttgtt aacaacaagg attatcccct tgagatgaaa
     6541 ggaactttag aaatcttatg atgaacatgc aaaacatgat gcgtcaagca caaaaacttc
     6601 aaaaacaaat ggaacaaagc caagctgaac ttgctgctat gcaatttgtt ggcaaatctg
     6661 ctcaagatct tgtccaagcg accttaactg gcgataagaa agttgtcagc attgatttca
     6721 atccagctgt cgttgaccca gaggaccttg agactctttc tgatatgacc gttcaagcca
     6781 tcaactctgc tcttgaacaa atcgatgaaa ctaccaagaa aaaactgggt gctttcgctg
     6841 ggaaattacc tttctaaaaa caaggagcta gaacaatgct tgtcgataac aaaggctaag
     6901 aaaggtgcaa aaatg
//
LOCUS       DBERCW010000062         6520 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.062, whole genome shotgun sequence.
ACCESSION   DBERCW010000062 DBERCW010000000
VERSION     DBERCW010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.062"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            131..331
                     /locus_tag="ACL72M_002000"
     CDS             131..331
                     /locus_tag="ACL72M_002000"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGS0717060.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            366..1082
                     /gene="atpB"
                     /locus_tag="ACL72M_002001"
     CDS             366..1082
                     /gene="atpB"
                     /locus_tag="ACL72M_002001"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGS0717061.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            1096..1590
                     /gene="atpF"
                     /locus_tag="ACL72M_002002"
     CDS             1096..1590
                     /gene="atpF"
                     /locus_tag="ACL72M_002002"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGS0717062.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            1590..2126
                     /locus_tag="ACL72M_002003"
     CDS             1590..2126
                     /locus_tag="ACL72M_002003"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGS0717063.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            2141..3646
                     /gene="atpA"
                     /locus_tag="ACL72M_002004"
     CDS             2141..3646
                     /gene="atpA"
                     /locus_tag="ACL72M_002004"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGS0717064.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            3662..4540
                     /locus_tag="ACL72M_002005"
     CDS             3662..4540
                     /locus_tag="ACL72M_002005"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGS0717065.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            4626..6032
                     /gene="atpD"
                     /locus_tag="ACL72M_002006"
     CDS             4626..6032
                     /gene="atpD"
                     /locus_tag="ACL72M_002006"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGS0717066.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            6043..6462
                     /locus_tag="ACL72M_002007"
     CDS             6043..6462
                     /locus_tag="ACL72M_002007"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGS0717067.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
BASE COUNT         1936 a         1220 c         1440 g         1924 t
ORIGIN      
        1 acttgaactt gaaatttagc aaaatggaaa taatttttat taaacgcttc caatagcggt
       61 taaaagttga caaatttaaa ttttaggact acactaagta agtaaatttt attttaaagg
      121 agaatttgtt atgaatttaa catttttagg cttatgtatt gcctgtatgg gcgtatctgt
      181 cggtgaaggt ttattgatga atggactgtt taaatcagta gcacgccaac cagatatgct
      241 ttctgagttt cgtagtttga tgtttttagg tgttgccttt attgaaggaa ctttctttgt
      301 aactcttgtc ttctcattta ttatcaaata aatacatgga acgagaagaa aagggaggat
      361 tttagatgga agaaagtatt aatccaatca tctctattgg tcctgttatc ttcaatctga
      421 ctatgttagc catgactttg ttgattgtgg gagttatttt tgtctttatt tattgggcaa
      481 gccgcaatat gaccttgaaa cccaaaggaa agcaaaatgt acttgagtat gtctatgact
      541 ttgttattgg atttacagaa cctaacattg gttcgcgcta catgaaagat tactcactct
      601 ttttcctttg tttattcctt ttcatggtga ttgccaataa ccttggctta atgacaaagc
      661 ttcaaacgat cgatgggact aactggtgga gttcgccaac cgctaattta cagtatgact
      721 taaccttatc ttttcttgtc attttgttga cacatataga aagcgttcgt cgtcgtggat
      781 ttaaaaaaag tataaaatct tttatgagtc ctgtttttgt cataccgatg aatatcttgg
      841 aagaatttac aaacttctta tctttggctt tgcggatttt tgggaatatc tttgcaggag
      901 aggtcatgac gagtttgtta cttcttcttt cccaccaagc tatttattgg tatccagtag
      961 cctttggagc taatttggct tggactgcat tttctgtctt tatttcctgc atccaagctt
     1021 atgtttttac tcttttgaca tctgtgtatt tagggaataa gattaatatt gaagaggaat
     1081 agaaaggagt aactgatgca cgtaacagta ggtgaattaa ttggtaattt tattttaatc
     1141 actggctctt ttattctttt gctagtcttg attaaaaaat ttgcatggtc taatattaca
     1201 ggcattttcg aagaaagagc tgaaaaaatt gcttcagata ttgacagagc tgaagaagcc
     1261 cgtcaaaaag cagaagtatt ggctcaaaaa cgcgaagatg aattggctgg tagccgtaaa
     1321 gaagctaaga caatcattga aaatgcaaag gaaacagctg agcaaagtaa ggctaatatc
     1381 ttagcagatg ctaaactaga agcaggacac ttaaaagaaa aagccaatca agaaattgct
     1441 caaaataaag tagaagcttt acagagtgtt aagggtgagg tcgcagattt gaccatcagc
     1501 ttagctggta aaatcatctc acaaaacctt gacagtcatg cccataaagc actcattgat
     1561 cagtatatcg atcagctagg agaagcttaa tggacaagaa aacagtaaag gtaattgaaa
     1621 aatacagcat gccttttgtc caattggtac ttgaaaaagg agaagaagac cgtatctttt
     1681 cagacttgac tcaaatcaag caagttgttg aaaaaacagg tctgccttct tttttaaaac
     1741 aagtggcagt agacgagtcg gataaggaaa aaacaattgc ttttttccaa gattctgtgt
     1801 cgcctttatt acaaaacttt atccaggttc tggcctacaa tcacagagca aatctttttt
     1861 atgatgtgct tgtagattgc ttgaaccgac ttgaaaaaga aacaaatcga tttgaagtga
     1921 cgattacgtc tgctcatcct ctaactgatg aacagaagac tcgtttgctc cctttgattg
     1981 agaaaaaaat gtctctgaaa gtaaggagtg taaaagaaca aatcgatgaa agtctcattg
     2041 gtggttttgt catttttgcc aatcacaaga caattgatgt gagtattaaa caacaactta
     2101 aagttgttaa agaaaatttg aaatagaaag tggtgttctt ttggcaatta acgcacaaga
     2161 aatcagcgct ttaattaagc aacaaattga aaatttcaaa cccaattttg atgtgactga
     2221 aacaggtgtt gtaacctata tcggggacgg tatcgcgcgt gctcatggcc ttgaaaatgt
     2281 catgagtgga gagttgttga attttgaaaa cggctcttat ggtatggctc aaaacttgga
     2341 gtcaacagac gttggtatta tcatcctagg tgactttaca gatatccgtg aaggcgatac
     2401 aatccgccgt acagggaaaa tcatggaagt ccctgtaggt gaaagtctga ttggtcgtgt
     2461 tgtggatccg cttggtcgtc cagttgacgg tcttggagaa atccacactg ataaaactcg
     2521 tccagtagaa gcaccagctc ctggtgttat gcaacgtaag tctgtttcag aaccattgca
     2581 aactggtttg aaagctattg acgcccttgt accgattggt cgtggtcaac gtgagttgat
     2641 tatcggtgac cgtcagacag ggaaaacaac cattgcgatt gatacaatct tgaaccaaaa
     2701 agatcaagat atgatctgta tctacgtcgc gattggacaa aaagaatcaa cagttcgtac
     2761 gcaagtagaa acacttcgtc agtacggtgc cttggactac acaatcgttg tgacagcctc
     2821 tgcttcacaa ccatctccat tgctcttcct agctccttat actggggttg ctatggcgga
     2881 agaatttatg tatcaaggta agcatgtttt gattgtatac gatgatctat caaaacaagc
     2941 ggtagcttat cgtgaactat cgctcttgct tcgtcgtcct ccaggtcgtg aagccttccc
     3001 aggggatgtt ttctatctcc acagccgttt gcttgagcgc tcagctaaag tttctgatga
     3061 acttggtggt ggatcaatta cagccctacc atttatcgag acacaagcag gagatatctc
     3121 agcctatatc gcaaccaacg tgatttctat cactgatgga caaatcttcc ttggcgatgg
     3181 cctcttcaat gcaggtattc gtccagccat cgatgcgggt tcatctgtat ctcgtgtagg
     3241 tggttctgca caaatcaaag ccatgaagaa ggttgctggt acacttcgta tcgaccttgc
     3301 ttcataccgt gagttggaag cctttactaa gtttggttct gacttggacg cagcaacaca
     3361 ggctaagttg aaccgtggac gtcgtaccgt tgaggtcttg aaacaacctg ttcacaaacc
     3421 attacctgtt gagaaacaag taaccattct ttatgctttg acacatggtt tcttggatac
     3481 tgttccagta gatgatattg ttcgtttcga ggaagagttc catgccttct ttgatgctca
     3541 acatccagag attttggaaa ccattcgtga tacaaaagac ttgccagaag aagcagtctt
     3601 ggatgctgcg attacagagt ttctcaatca atctagcttc caataagaat agaggtgtca
     3661 gatggcagtg tctctaaatg atattaaaac aaaaatcgcc tcaacaaaaa atacgagtca
     3721 aatcactaat gccatgcaaa tggtatcggc tgctaagtta ggtcgctctg aagaagctgc
     3781 tcgcaacttc caagtttacg ctcagaaagt gcgtaaactt ttgacagata tccttcatgg
     3841 taatggagct ggtgcttcaa ctaatccgat gttgattagc cgttctgtga agaagacagg
     3901 ctatatcgtt atcacttcag accgcggttt ggttggaggt tataattcct ctattttgaa
     3961 agctgttatg gagttgaaag aagaatacca cccagacggt aaaggttttg aaatgatctg
     4021 tatcggtggg atgggagctg atttctttaa ggctcgcggt attcaaccac tttatgaatt
     4081 acgtggcttg gcagaccaac ctagctttga tcaagttcgt aagattattt caaaaactgt
     4141 tgaaatgtac caaaatgaac tctttgatga gctttatgtt tgctacaacc accatgtcaa
     4201 tacgctaacc agtcaaatgc gtgtggaaca aatgcttccg attgttgact tggatccaaa
     4261 tgaagcggat gaagagtaca gcttgacttt tgaattggaa accagccgag aagaaattct
     4321 ggagcagttg ttgcctcagt ttgcagaaag tatgatttac ggtgccatta tcgatgccaa
     4381 gacagctgag aatgctgcgg gtatgacagc catgcaaaca gcgacagata atgctaagaa
     4441 agtcatcaat gatttgacaa ttcagtataa ccgtgccaga caggcggcga ttacacaaga
     4501 aattacagaa atcgtagcag gtgctagtgc cttagaatag gctctagtcc agctcgtatg
     4561 aaaatgaact taggacctag ttgagctagg aaccgacagt atcttatata gaataggaga
     4621 aggagatgag ttcaggtaaa attgctcagg ttatcggtcc cgttgtagac gttttgtttg
     4681 cagcagggga aaaacttcct gagattaaca atgcacttgt cgtctacaaa aatgacgaaa
     4741 gaaaaacaaa aatcgtcctt gaagtagcct tggagttagg agatggtatg gttcgtacta
     4801 tcgccatgga atcaacagat gggttgactc gtggaatgga agtattggac acaggtcgtc
     4861 caatctctgt accagtaggt aaagaaactt tgggacgtgt cttcaacgtt ttgggagata
     4921 ccattgattt ggaagctcct tttacagaag acgcagagcg tcagccaatt cataaaaaag
     4981 ctccaacttt tgatgagttg tctacctctt ctgaaatcct tgaaacaggg atcaaggtta
     5041 ttgaccttct tgccccttac cttaaaggtg gtaaagttgg acttttcggt ggtgccggag
     5101 ttggtaaaac cgtcttaatc caagaattga ttcacaacat tgcccaagag cacggtggta
     5161 tttcagtatt tactggtgtt ggggaacgta ctcgtgaggg gaatgacctt tactgggaaa
     5221 tgaaagaatc aggcgttatc gagaaaacag ccatggtctt tggtcagatg aatgagccac
     5281 caggagcacg tatgcgtgtt gcccttactg gtttgacaat cgctgaatac ttccgtgatg
     5341 tggaaggcca agacgtgctt ctctttatcg ataatatctt ccgtttcact caggctggtt
     5401 cagaagtatc tgcccttttg ggtcgtatgc catcagccgt tggttaccaa ccaacacttg
     5461 ctacggaaat gggtcaattg caagaacgta tcacatcaac caagaagggt tctgtaacct
     5521 ctatccaggc tatctatgtg ccagcggatg actatactga cccagcgcca gcaacagcct
     5581 tcgctcactt ggattcaaca acaaacttgg aacgtaaatt ggtacaattg ggtatctacc
     5641 cagccgttga cccacttgct tcaagctcac gtgccttggc acctgaaatc gttggagaag
     5701 agcactatgc agttgctgct gaagtaaaac gtgtccttca acgttaccat gaattgcaag
     5761 atatcattgc tatccttggt atggatgagc tttctgatga agaaaagacc ttggttgctc
     5821 gcgcccgtcg tatccagttc ttcttgtcac aaaacttcaa cgttgcggaa caatttactg
     5881 gtcagccagg ttcttatgtt ccagttgctg aaactgtacg tggctttaag gaaatccttg
     5941 atggtaaata cgaccacttg ccagaagatg ccttccgtgg tgtaggttct atcgaagatg
     6001 tgattgcaaa agctgaaaaa atgggatttt aagaggtgac ctatggctca gttaactgtc
     6061 cagatcgtga caccagatgg tctcgtctat gatcaccatg ccagctatgt atcggttcga
     6121 actctggatg gtgagatggg gatcttgcca cgacatgaaa atatgattgc ggttttagca
     6181 gttgatgaag taaaggtaaa acgtatcgat gataaagatc acgtgaactg gattgcagta
     6241 aacggtggcg ttattgaaat tgccaatgat atgatcacaa tcgtcgctga ctctgcagaa
     6301 cgtgctcgtg atatcgatat tagccgtgca gaacgtgcca aacttcgtgc agaacgtgca
     6361 attgaagaag cacaagacaa acatttgatt gaccaagaac gtcgtgctaa gattgctttg
     6421 caacgtgcca ttaaccgtat taatgtcgga aatagactat aagaaaaaat gaacttgaaa
     6481 ataccaagtt cattttttag gctctttgtc aactgtagtg
//
LOCUS       DBERCW010000063         6500 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.063, whole genome shotgun sequence.
ACCESSION   DBERCW010000063 DBERCW010000000
VERSION     DBERCW010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.063"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            116..1091
                     /locus_tag="ACL72M_002008"
                     /pseudo
     CDS             116..1091
                     /locus_tag="ACL72M_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            1268..2275
                     /gene="gap"
                     /locus_tag="ACL72M_002009"
     CDS             1268..2275
                     /gene="gap"
                     /locus_tag="ACL72M_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGS0717068.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2343..3218)
                     /locus_tag="ACL72M_002010"
     CDS             complement(2343..3218)
                     /locus_tag="ACL72M_002010"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0717069.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVRWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3305..5500
                     /gene="pbp2a"
                     /locus_tag="ACL72M_002011"
     CDS             3305..5500
                     /gene="pbp2a"
                     /locus_tag="ACL72M_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGS0717070.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYNSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5553..5705
                     /gene="rpmG"
                     /locus_tag="ACL72M_002012"
     CDS             5553..5705
                     /gene="rpmG"
                     /locus_tag="ACL72M_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0717071.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5715..5891
                     /gene="secE"
                     /locus_tag="ACL72M_002013"
     CDS             5715..5891
                     /gene="secE"
                     /locus_tag="ACL72M_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGS0717072.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5946..6482
                     /gene="nusG"
                     /locus_tag="ACL72M_002014"
     CDS             5946..6482
                     /gene="nusG"
                     /locus_tag="ACL72M_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGS0717073.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2020 a         1132 c         1414 g         1934 t
ORIGIN      
        1 accaagttgc aatacctttt atgaggctct tttgtcctgc tcttgtttca attgactata
       61 gttcacggat acagttggga aagaagctat taaatatttg gagagtcctt ttgggatgaa
      121 catgtcaaat attactatag atgggcaaga aaagatgggc aagaaatgga tctgagtcaa
      181 acgatgcttc ttatgctcaa gtagtgagtc tttatgatga tacaagtatc tctgttagta
      241 ataatgagac ggacaaagtg ttgactggat ccctctatac tgaaacaaat gaacagggat
      301 taacgattcc aagcagttta ctaaaaaatt ggaatgaaca gacaggaaaa aatttgacaa
      361 ctaatgatct tattggcaaa tcagtctcag ccagcattgt agaaagtgct gccgaaacta
      421 gtaagattgc tcaatttcaa acgaagattg tacgtgtaat caatgatgaa gatgacatgg
      481 aggacagcaa cagtttcatg ctgtctcatc aaatggaaac gattttgaaa gaggctggat
      541 ttacgaaagc tgtatcttat tttatcttgg aactcaaaga tccatcacag acaaaagtag
      601 taacagaaga attacagaaa aataagaagt atactgtgct ttctcaacag agagttcttg
      661 atattgtgat tacctttatt cgtgttattc agggattatt gattgtgctt tcatcacaag
      721 ctattgtggt agcagcggtt atgattggta tcattattta catcaatatc atgcaacgtt
      781 ccaaggaaat aggtgtcatg aaagcagttg gttatcagaa tcgtggtgtc aaaggaattt
      841 ttatttacga ggctatctgg attgtaggca tcgccttgct gctggcattt ttggttgcac
      901 aaggggtggg aagtttggcg aatgcgattg taagtcactt ttacccatcc atcactaagg
      961 tttttgaatt aaatctttta tctgttttag gaactctagt tttcgctcta ttacttggtt
     1021 atgtctcagc ctacttcccg gcgcgtaaga ttagtaaaat ggatcctgta gaatcgttac
     1081 gctatgaata ataagggatt ccttgattta cagtcttaaa aagaaactca catagaaaaa
     1141 caatggccat acttgcaatt caactcaaat agttgtataa taggtttgtt gaaaggtgat
     1201 ttgtagtgat tcaagttact cttttcacaa taaaaatttc atgattttca taaggaggaa
     1261 atcactaatg gtagttaaag ttggtattaa cggtttcgga cgtatcggtc gtcttgcttt
     1321 ccgtcgtatc caaaacgtag aaggtgttga agttacacgc atcaacgacc ttacagatcc
     1381 agttatgctt gcacacttgt tgaaatacga cacaactcaa ggtcgtttcg acggtactgt
     1441 tgaagttaaa gaaggtggat tcgaagttaa cggtaaattc gttaaagttt ctgctgaacg
     1501 tgatccagag caaatcgact gggctactga cggtgtagaa atcgttcttg aagctactgg
     1561 tttctttgct aagaaagaag cagctgaaaa acaccttaaa ggtggagcta aaaaagttgt
     1621 tatcactgct cctggtggaa acgacgttaa aacagttgta ttcaacacta accacgacgt
     1681 tcttgacggt actgaaacag ttatctcagg tgcttcatgt actacaaact gcttggctcc
     1741 aatggctaaa gctcttcaag ataactttgg tgttgttgaa ggattgatga ctactatcca
     1801 cgcttacact ggtgaccaaa tgatccttga cggaccacac cgtggtggtg accttcgccg
     1861 tgctcgcgct ggtgctgcaa acatcgttcc taactcaact ggtgctgcaa aagctatcgg
     1921 tcttgtaatc ccagaattga atggtaaact tgatggatct gcacaacgcg ttccaactcc
     1981 aactggatca gttactgaat tggtagcagt tcttgaaaag aacgttactg ttgatgaagt
     2041 gaacgcagct atgaaagcag cttcaaacga atcatacggt tacacagaag atccaatcgt
     2101 atcttcagat atcgtaggta tgtcttacgg ttcattgttt gacgcaactc aaactaaagt
     2161 tcttgacgtt gacggtaaac aattggttaa agttgtatca tggtacgaca acgaaatgtc
     2221 atacactgca caacttgttc gtactcttga atacttcgca aagattgcta aataattctt
     2281 gagttgatag aaagcaaggc tttgtggtct tgctttttta tatggaaaaa tggatgacac
     2341 gatcatccat tcttttttaa ttctttttca aatgtatttg aaagggtagt gaaagttagc
     2401 ctctctaaag taagtgggtg ggtaaaggaa agtcggaagg catgaagcat aagccggctt
     2461 gtctttgatt tactattata gagagggtct cccaggatag gaagattatg atgcaaaagg
     2521 tgcacacgaa tctgatgggt tcgccctgtc tttagcttgc aatgagccaa ggaagtcttg
     2581 tttgagaatt gctttaatct gcttacatgc gtttcagcat atttcccatt ttttgcatca
     2641 actattcttt ttctacgatc atggcgatca cgtccaattt tgtctctgaa aacaagttct
     2701 tttctgttga tatttccatc aactagagcc caatattctc tagaaatctc ttttttctcc
     2761 aataagcgat tgagaatggg caggataaaa ggatttttgg caaagagaac taagccactg
     2821 gtttccatgt ccagacgatg aacgacatag caggtttggc caacataggt actgacatgg
     2881 ttaagaaggg caatttcgtt tggttgatta ccatgcgttt tcatcccctc tggtttgttt
     2941 acaataatca agtgttgatc ttgataaact tcctgcacta agtctgggtt gccccaaggg
     3001 atcgtctttt ggggataatc ttcctcgtca aaagtcaact ggcaaacatc tccaggattt
     3061 acgatttcgt tccagcggac ttcttcttga tttatcaaaa tatgtttctt gattctcaaa
     3121 aaatgacgga tttttctagg gatgaggagt tgttcctcaa gtaattgctt taccgtcatt
     3181 tgaggtagag aggcgggtaa tgtaaatgtg aattgcatac agatattgta acaaaaaaag
     3241 ccctatttgg ataggaaata gctaaattct tgtcttccta tgatgaagat gataaaataa
     3301 acgcatgaaa ttagataaat tatttgagaa atttctttct ctttttaaaa aagaaacaag
     3361 tgaactagag gactctgatt ctactatctt acgtcgctct cgtagtgatc gaaaaaaatt
     3421 agcccaagta ggtccgattc gaaaattctg gcgtcgttat catctaacaa agattatcct
     3481 tatactaggt ttgagtgcag gcttgctagt tggaatctat ttgtttgctg tagccaagtc
     3541 gaccaatgtc aatgatttgc aaaatgcctt gaaaactcgg actcttattt ttgaccgtga
     3601 agaaaaagag gctggtgcct tgtctggtca aaagggaacc tatgttgagc tgactgacat
     3661 cagtaaaaac ttgcagaatg ctgttattgc gacagaagac cgttctttct ataaaaatga
     3721 cgggattaac tatggccgtt tcttcttggc tattgtcact gctggacgtt caggtggtgg
     3781 ctctaccatt acccaacagc tggctaaaaa cgcctattta tcgcaggatc aaactgttga
     3841 gagaaaagcg aaagaatttt tccttgcctt agaattaagc aaaaaatata gtaaggagca
     3901 aattctaacc atgtacctta acaacgctta ttttggaaat ggtgtgtggg gtgtagaaga
     3961 tgcgagtaag aaatactttg gagtttctgc atcagaagtg agtctggatc aagctgcgac
     4021 tctggcaggg atgctcaagg ggccggaact gtataatccc ttgaattccg tagaagattc
     4081 tactaatcgg cgcgatactg tcttgaagaa tatggttgca gcaggatata ttgataaaaa
     4141 ccaagaaacc gaagctgctg aagttgatat gacttcgcaa ttgcacgata agtatgaagg
     4201 aaaaatctca gattaccgtt acccctctta ttttgatgcg gtggttaatg aagctgtttc
     4261 caagtataat ctaacagagg aagagattgt caataatggc taccgcattt acacagagct
     4321 ggaccaaaac taccaagcaa atatgcagat tgtttatgaa aacacatcgc tatttccgag
     4381 ggcagaggat ggaacgtttg ctcaatcagg aagtgtagct ctcgaaccga aaacaggggg
     4441 agttcgtgga gttgtcggtc aagttgctga caatgataaa actggattcc ggaatttcaa
     4501 ctatgcaacc caatcaaagc gtagtcctgg ttctacaatt aagcctttag ttgtttatac
     4561 gccagcagtt gaagcaggct gggctttgaa taagcagttg gataaccata ccatgcagta
     4621 taacagctat aaggttgata actatgcagg gatcaaaacg agtcgagaag ttcctatgta
     4681 tcaagccttg gcagaatcgc ttaatctacc tgctgttgcc actgttaatg atttgggtgt
     4741 tgacaaggct tttgaggcag gcgaaaaatt cggactcaac atggaaaagg tcgaccgtgt
     4801 tcttggtgtc gccttgggaa gcggtgttga aaccaaccct cttcaaatgg ctcaagcata
     4861 cgctgccttt gcaaatgaag gtttaatgcc tgaagctcat tttattagta gaattgaaaa
     4921 tgctagtgga caagttattg cgagtcataa aaattcacaa aaacgggtga ttgataagtc
     4981 tgtagctgac aagatgacca gtatgatgtt ggggactttc accaacggta ccggtattag
     5041 ttcatcgcct gcagactata ttatggcagg gaaaactgga acaactgaag cagttttcaa
     5101 tccggagtac acaagtgacc agtgggtaat tggttatact ccggatgtag tgattagcca
     5161 ctggcttggc tttcctacca ctgatgaaaa tcactatcta gctggctcta cttcaaacgg
     5221 tgcagctcat gtctttagaa acattgccaa taccatttta ccttatacgc caggaagtac
     5281 ctttacggtt gaaaatgctt ataagcaaaa tggaattgca ccagccaata caaaaagaca
     5341 agtacaaacc aatgataata gccagacaga tgataatttg tctgatattc gagggcgtgc
     5401 gcaaagtcta gtagatgagg ctagccgggc tatctcagat gcgaagatta aggaaaaggc
     5461 tcaaacaata tgggattcga tagtcaatct atttcgttaa gatgcttgtc aaagcctagc
     5521 tttcttgtta taatggataa gatggaggcg ttatggcact aaaaaaagca agcctagctt
     5581 gtgcggtttg tggttcgaga aactattcaa tcaagatcag cggaaacccc aagcctacac
     5641 gactagaagt aaataaattt tgtaagcatt gtggcaagta cactacacac agagaaacga
     5701 gataggagag agcgatgcgt tttattggag atatttttag acttcttaaa gacacaacat
     5761 ggccaactcg caaggaaagc tggagagatt ttcgttctat catggaatac acagctttct
     5821 ttgtagtaat tatttacatt tttgaccagt tgattgtttc aggtttgatt cgatttatta
     5881 acatttttta gaagattagt ggagttaatt acactagaaa tcttctattt atgaaaggaa
     5941 atatcatgga tagttttgat aaaggatggt ttgttttaca aacttattct ggttatgaaa
     6001 ataaggtgaa agaaaatcta ttacaacgtg cacaaaccta caatatgttg gataatattc
     6061 tacgcgttga aattccaaca caaacagtgc aagttgaaaa aaatggaaag agaaaagaag
     6121 tagaagaaaa tcgctttcca ggttatgttc ttgtagaaat ggtcatgaca gatgaagctt
     6181 ggtttgttgt tcgaaacaca ccaaatgtta caggatttgt cggatcacac gggaacagat
     6241 caaaaccaac tccattattg gaacaagaaa ttcgtgacat tttggtatct atgggacaaa
     6301 ctgttcaaga atttgatttc gatgttgaga ttggtcaaac tgtacgtatt attgatggtg
     6361 cttttgcaga ctacactggt aagattacag aaattgataa taacaaagtg aaaatgatta
     6421 tctctatgtt tggtaatgac acagttgcag aagtaaacct aaaccaaatc gcagaattat
     6481 aaccctgaga gaggctggag
//
LOCUS       DBERCW010000064         6417 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.064, whole genome shotgun sequence.
ACCESSION   DBERCW010000064 DBERCW010000000
VERSION     DBERCW010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.064"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..380
                     /locus_tag="ACL72M_002015"
                     /pseudo
     CDS             1..380
                     /locus_tag="ACL72M_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            547..747
                     /locus_tag="ACL72M_002016"
     CDS             547..747
                     /locus_tag="ACL72M_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717074.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            789..1194
                     /locus_tag="ACL72M_002017"
                     /pseudo
     CDS             789..1194
                     /locus_tag="ACL72M_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
     gene            1425..2132
                     /gene="ccdA2"
                     /locus_tag="ACL72M_002018"
     CDS             1425..2132
                     /gene="ccdA2"
                     /locus_tag="ACL72M_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS0717075.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2143..2700
                     /gene="sdbB"
                     /locus_tag="ACL72M_002019"
     CDS             2143..2700
                     /gene="sdbB"
                     /locus_tag="ACL72M_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGS0717076.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3074..4465
                     /locus_tag="ACL72M_002020"
     CDS             3074..4465
                     /locus_tag="ACL72M_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGS0717077.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4608..5525
                     /gene="adcAII"
                     /locus_tag="ACL72M_002021"
     CDS             4608..5525
                     /gene="adcAII"
                     /locus_tag="ACL72M_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGS0717078.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5533..>6417
                     /gene="phtD"
                     /locus_tag="ACL72M_002022"
     CDS             5533..>6417
                     /gene="phtD"
                     /locus_tag="ACL72M_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGS0717079.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPVQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGL"
BASE COUNT         1977 a         1162 c         1352 g         1926 t
ORIGIN      
        1 aactaccatc cactatgcgc tcaaagctat gggttacact cgaaaaaaag aaccacacct
       61 actatgaaca agacccagaa aaagtagcct tatttcttaa gaattttaat agtttaaagc
      121 acctagcacc tgtttagatt gacgaaacag gattcgatac ttatttttat cgagaatatg
      181 gtcgctcatt aaaaggtcag ttaataagag gcaaagtatc tggaagaaga tatcagagga
      241 tttctttggt tgcaggtcta acaaatggtg aattaatcgc tccaatgact tacgaagaga
      301 tgatgacgag cgactttttt gaagtatggt ttcagaagtt tctcttacca acattaacca
      361 caccatcggt tattatagta aaatgaaata agaacaggac aaatcgatca ggacagtaaa
      421 atcgaattct aacaatgttt tagaagtcca tatgtactat tctagtttca atataccata
      481 actgttccta gtcaacctgc aagccctgtc ccagctccaa gctcagctcc gactcaagat
      541 cctagagtgg tagcaagcgc ttcggctagc tcaacgagca cacaagctca agagcaagtt
      601 gacaagtctg aacttcgtgc cttgagtcaa gagttagacc aacgcttgaa agctttggca
      661 acagtatctg atccgaaaat cgatgcaacc aaggctgtcc tcctagatgc tcaaaaagct
      721 ccggaagata gtgccttgac agagtaaggt ctgcatactg cagtagagtc tgtgaaggct
      781 gggctgcctt ggactctctc aaagatgtga aagcaaatgc tagcgacagc aagcctacac
      841 aggacaagaa ggatgcaaaa caaggaacgg aagatagtaa ggattcagat aagatgactg
      901 aaacaaactc agttccagca ggagtgattg tggtcagtct acttgccctc ctaggcgtga
      961 ttgccttctg gctaattcgc cgtaagaaag agtcagaaat ccagcaatta agcacggaat
     1021 tgaccaaggt tctaggacag ctagatgcag aaaaaagcgg ataaaaaagt ccttgccaaa
     1081 gcccaaaacc ttctccaaga aacccttgat ttcgtgaaag aagaaaatgg ctcagcagag
     1141 acagaaacta aactagtaga ggagcttaaa gcaatccttg acaaactcaa gtaaaacatg
     1201 atttatgaaa tgtcagacct aaaagacatt ttcgttcaca aaagcagcga cgagtaatcc
     1261 ttgtcgttgc tttttggcta ttttggggga taagatccgc cttgactagc aaaagaaaag
     1321 attggtccaa tagtgcccga tacgattttg cgtagcagaa agcttacaaa taaaattgaa
     1381 tatagtaaaa taggattaga attattaaga aagttggttc tttattggaa acgatagtat
     1441 ttttaatctc tgtttttcta gcaggtgttt tatccttttt ttctccttgt atttttcctc
     1501 ttctgccagt ctatgctggg attttattgg atgatcaaga aagtgcaaaa agcttttctt
     1561 tgtttgggag aaaggttctc tggtcaggct tgattcgaac actttgcttt atcgctggta
     1621 tctctctcat tttctttatt ctaggctttg gtgctggtta ctttggtcat attctctatg
     1681 caaattggtt tcgatatggc atgggagcta ttattatcat tttgggtctt caccagatgg
     1741 aaatttttca tttgaagaaa ttagaagttc aaaaaagttt tacctttaaa aaatcagact
     1801 ctaatcgtta ttggtcagct tttttacttg gtattacctt tagctttggt tggacacctt
     1861 gtattggtcc agttttaagt tctgttttag cacttgcggc ttctggaggc aatggcgctt
     1921 ggcaaggagc gatttatact ctcatttaca ctctgggcat ggcccttcct ttcttggtat
     1981 tggcactagc ttcaggtcta gtcatgccat attttagtaa aatcaagcgt catatgatgc
     2041 tactaaagaa aattggtggt ttcctcattg ttttaatggg aattttgtta ctattaggac
     2101 aagtaaatgt tctagctgga atttttgaat aaaggaggac aaatgaaaaa agtaatgttt
     2161 gctggcttaa gtctcttgtc attagttgta ttgatggcct gtggtgagga agaaactaaa
     2221 aagactcaag cagcacaaca gccaaaacaa caaacgactg tacaacaaat tgctgttgga
     2281 aaagatgctc caaacttcac attgcaatcc atggatggca aagaagttaa gttatctgat
     2341 tttaagggta aaaaggttta cttgaagttt tgggcttcat ggtgtggtcc atgcaagaaa
     2401 agtatgccag agttgatgga actagcggcg aaaccagatc gtgatttcga aattcttact
     2461 gtcattgcac caggaattca aggtgaaaaa attgttgagc aattcccaca atggttccag
     2521 gaacaaggat ataaggatat cccagttctt tatgatacca aagcaaccac cttccaagct
     2581 tatcaaattc gaagcattcc tacagaatat ttaattgata gccaaggaaa gattggaaag
     2641 attcaatttg gtgctatcag taatgcggat gcagaagcag catttaaaga aatgaactag
     2701 aatcgataaa atctgattac aagatgtagt cagattttgg taacttctaa aactaacttc
     2761 cagtttccca caacctagct tttagtatga gaaaaacgcg tgacatcagt ggaaatccgt
     2821 cttagactaa cttccactgg ttttcttttt cttgatatat aagggttcaa aagcgaaaag
     2881 actcagaaaa agtgcacgac aaatagccct aaaacagagt cgtcttagag taacttccag
     2941 ttttgggaga gagatggaag ttactttgag aagttacggt agtcagattt ttttagaaaa
     3001 acattttata aatattcaca tatctcctat atttatggta aaatagaatc atcagtttat
     3061 tttggagtca aagatgaata tatttagaac aaagaatgtt agtttagata aaacagagat
     3121 gcataggcat ttgaagttat gggatttgat tttgctgggt atcggagcca tggtagggac
     3181 aggcgtcttt acaatcacag gtactgcagc tgcaacactt gctggcccag ccctagtgat
     3241 ttcaatcgtt atttctgcct tgtgtgtggg attatcagcc ctcttttttg cagaatttgc
     3301 ctcgcgagta cccgctacag gaggtgccta tagttacctc tatgctatct taggagaatt
     3361 ccctgcctgg ttggctggtt ggttaaccat gatggagttc atgacagcca tatcaggcgt
     3421 agcttcgggt tgggcagctt attttaaagg cttgctctct caatacggga tagcctttcc
     3481 tcaggcttta aatggtacct ttaatcctca agcagggaca tttgttgatt tattgcctat
     3541 tcttgtcttg gtcttggtga cttcgcttgt tttactaaat gccaaggcag ccttacgctt
     3601 taattcgatt ctagttattt tgaaattttc cgctttagct ctctttgttt tagtaggaat
     3661 ttggaatatt aagtttgata attggagcaa ttttgctcct tacggttttg gacaaatcta
     3721 tggagctagc actggtatta tggctggtgc gtccttgatg ttcttcggtt ttttgggatt
     3781 tgaatccatc tctatggctg tagatgaagt caagactcct caaaaaaata ttcctagagg
     3841 gattgtctta tcgctttcta tcgtaaccat tctctatgcc ttggtgaccc ttgttttgac
     3901 tggtgtggtt cactatagtc atttaaatgt cgatgatgcc gttgcctttg cccttcgtag
     3961 tgttgggatt agttgggcag ccaactatgt gtcattagtg gctatcttga ccttgattac
     4021 agtttgtatt tcgatgacct atgccctatc gcgtatgatt tacagtttag cacgtgacgg
     4081 cttagtgcct gctgccttta aggaactgac gaagactagc aagataccaa agaatgctac
     4141 tatcttgaca ggtctagctt cagcagtagc agcaggaatg ttcccactag ccagtattgc
     4201 agccttttta aatatttgta ccttagccta cttgatcatg ttggcttatg gtctgattcg
     4261 cttacggaaa gaaaaaggaa tgcccaaagc tggggaattt aaaacaccat tggtacctct
     4321 gttaccaatt ttatcgatca tcatttgttt atccttcatg ttacagtata atatgaatac
     4381 ctggattgct ttcctagttg cgttgttagt aggaagtatt atttacttca cttatggcta
     4441 taagcattct accatagaag aataaagtga aagtctattg agttgttgac actcagcaga
     4501 tttttatatg tgaaagaaat ttcaaatttt ttctaaaaat atcttgacag attaaatttt
     4561 caggagtaga atatttacta gttaattaaa tggttaagga gttgttcatg aagaaacaaa
     4621 atttattttt agtcctgtta agtgtctttc ttttgtgctt gggggcttgt ggtcaaaagg
     4681 aaagtcagac aggaaagggg atgaaaattg tgaccagttt ttatcctatc tacgctatgg
     4741 ttaaggaagt atctggtgac ttgaatgatg ttcggatgat tcagtcaagt agtggtattc
     4801 actcctttga accttcggca aatgatatcg cagccatcta tgatgcagat gtctttgttt
     4861 accattctca tacactcgaa tcttgggcag gaagtctgga tccaaatcta aaaaaatcca
     4921 aagtgaaggt cttagaggct tctgagggaa tgaccttgga acgtgtccct ggactagagg
     4981 atgtggaagc aggggatgga gttgatgaaa aaacgctcta tgaccctcac acatggctag
     5041 atcctgaaaa agctggagaa gaagcccaaa ttatcgctga taaactttca gaggtggata
     5101 gtgagcataa agagacttat caaaaaaatg cgcaagcctt tatcaaaaaa gctcaggaat
     5161 tgactaagaa attccaacca aaatttgaaa aagcgactca gaaaacattt gtaacacaac
     5221 atacagcctt ttcttatcta gcgaagagat ttgggcttaa tcaacttggt attgcaggta
     5281 tctctcctga acaagaacca agtccacgac aactaacaga aattcaggaa tttgttaaga
     5341 cctataaggt taaaacgatt tttacagaaa gtaacgcttc ttcaaaagta gctgaaactc
     5401 ttgtcaaatc aacaggtgtg ggtcttaaaa ctctgaatcc tttagagtca gacccacaaa
     5461 atgacaagac ctatttagaa aatcttgaag aaaatatgag tattctagca gaagaattaa
     5521 agtgaggaaa gaatgaaaat caataaaaaa tatctagcag gttcagtggc agtccttgcc
     5581 ctaagtgttt gttcctatga acttggtcgt caccaagctg gtcaggttaa gaaagagtct
     5641 aatcgagttt cttatataga tggtgatcag gctggtcaaa aggcagaaaa tttgacacca
     5701 gatgaagtca gtaagagaga ggggatcaac gccgaacaaa ttgttatcaa gattacggat
     5761 caaggttatg tgacctctca tggagaccat tatcattact ataatggcaa ggttccttat
     5821 gatgccatca tcagtgaaga acttctcatg aaagatccga attatcagtt gaaggattca
     5881 gacattgtca atgaaatcaa gggtggctat gtgattaagg tagacggaaa atactatgtt
     5941 taccttaaag atgcggccca tgcggacaat attcggacaa aagaagagat taaacgtcag
     6001 aagcaggaac gcagtcataa tcataactca agagcagata atgctgttgc tgcagccaga
     6061 gcccagggac gctacaccac agatgatggt tatatcttta atgcttctga tatcattgag
     6121 gacacgggtg atgcttatat cgttcctcac ggcgaccatt accattacat tcctaagaat
     6181 gagttatcag ctagcgagtt agctgctgca gaagcctatt ggaatgggaa gcagggatct
     6241 cgtccttctt caagttctag ttataatgca aatccagttc aaccaagatt gtcagagaac
     6301 cacaatctga ctgtcactcc aacttatcat caaaatcaag gggaaaacat ttcaagcctt
     6361 ttacgtgaat tgtatgctaa acccttatca gaacgccatg tggaatctga tggcctt
//
LOCUS       DBERCW010000065         6341 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.065, whole genome shotgun sequence.
ACCESSION   DBERCW010000065 DBERCW010000000
VERSION     DBERCW010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.065"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..3315
                     /locus_tag="ACL72M_002023"
     CDS             <1..3315
                     /locus_tag="ACL72M_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HGS0717080.1"
                     /translation="EGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANS
                     LDAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGS
                     IRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHV
                     TGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHY
                     LFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGAT
                     SGTAWVTGIKVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNK
                     DGQRQEALQRYTREESARQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKD
                     IASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNR
                     INSNKQGADNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLVRK
                     VETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKN
                     SDFKNGTNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDY
                     VLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGE
                     MDNAYIRFDNNGSSSGTADLYITEVDLYKGYKSRTWQPHPEDAVADANKKLEATQTKM
                     TQLAGSWVVENINSAGDIISGINLGANGHNRLVGKLTHITGETLIDRAVIKSAMVDKL
                     KTANFEAGSVTTTILEAEAVTAEKLKVDDALIRKLTAKDAFIDRLTSKRIFSIKVESV
                     ISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGN
                     NWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIEL
                     GSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDKIN
                     RLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKA
                     IQELNQKIEKMEKTIA"
     gene            3312..3428
                     /locus_tag="ACL72M_002024"
     CDS             3312..3428
                     /locus_tag="ACL72M_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HGS0717081.1"
                     /translation="MNNNMLTNIALKAIQELALENRKRTHRLENLENEHRTA"
     gene            3409..3612
                     /locus_tag="ACL72M_002025"
     CDS             3409..3612
                     /locus_tag="ACL72M_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717082.1"
                     /translation="MNTEQLNQALRMTISEISTTSTNSMITSNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            3615..3965
                     /locus_tag="ACL72M_002026"
     CDS             3615..3965
                     /locus_tag="ACL72M_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717083.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            3974..4390
                     /locus_tag="ACL72M_002027"
     CDS             3974..4390
                     /locus_tag="ACL72M_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HGS0717084.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            4394..4726
                     /locus_tag="ACL72M_002028"
     CDS             4394..4726
                     /locus_tag="ACL72M_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGS0717085.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKRDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            4735..5691
                     /gene="lytA"
                     /locus_tag="ACL72M_002029"
     CDS             4735..5691
                     /gene="lytA"
                     /locus_tag="ACL72M_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGS0717086.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHWR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYWFDNSGEMATGWKKIADKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTMADKPEFTVEPDGLITVK"
     gene            complement(5829..6008)
                     /locus_tag="ACL72M_002030"
     CDS             complement(5829..6008)
                     /locus_tag="ACL72M_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717087.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(6150..6299)
                     /locus_tag="ACL72M_002031"
     CDS             complement(6150..6299)
                     /locus_tag="ACL72M_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717088.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
BASE COUNT         2042 a         1183 c         1441 g         1675 t
ORIGIN      
        1 gaaggaaccg tttggatttg gatgccgaag tttgaaataa gcgatgtaga tacttcttat
       61 tcagaagctc ctgaagatat agaaggtcag atttcaacag ttgaatcgac cttcaaacaa
      121 cgagccaact cactcgacgc tggtgtaagc cgtctgactg aaggccttag aaccaaagcc
      181 gatatcagct cactcaatgt gactgctgaa aatatccggc aatctgtgaa gagtcttgag
      241 acagacacgc agaacaaact aaatcagaag ttgagtcagg ctgaatttga ggtgcgagct
      301 ggctctatcc gtcaggaaat cctgaacgca accaaggata aagcagataa gactttagtt
      361 gtatctgaag ctgggaaatt gcgagaagaa ttttcaaaaa tgaaggtggg aggccggaat
      421 ctatggataa aatccaagac ggttggagct gtaattgaaa aattacctga aaaccacgtc
      481 acaggtcaaa aagaatgcta taggctagag aacaactcta ctttaacgtt caaccttgaa
      541 ccagatttca gctcaaggtt gtaccaaaaa gttactttta gcgcttggat caagtacgaa
      601 aatgtagtcc aaggtcgaaa tttttggaat gtatttaatt gcttcaaaca ttatcttttt
      661 agaaaaaata gtgagaccgg agtacagagt ggtccagatt atgctacgct tggtatgtat
      721 aaaggttcgg cagattggaa atatattaca ttcacttatg actactctga aaaaacaaat
      781 tttgatcaat tgaagacatc attgcgattc aatcttgaag gtgctacaag cggtacagct
      841 tgggtaacag gaatcaaggt tgaaatcggt agtgtggcga cggactggag tcctgcgcct
      901 gaggacgctg atggtctcat tactgaagct aaggctacct ttgagcggac agctcagggc
      961 ttgcgaaccg acttatcagc tattcaggaa tatgtaaata aagacggtca gcgacaggaa
     1021 gccctacagc gctatactcg tgaggagagc gcgagacaag cgacagcagt ccgtgagctg
     1081 gtcaatcgtg atttcgttgg taaggctact tatcaagaag atgttaaggg tatcaatcaa
     1141 aggattgaag ctgttaaaac tagtgcgaat aaagacatcg ctagtcaaat cgctagctat
     1201 cgtcaatctg tagatggtaa gttcacggat atttcaagtc agataactac ttataagcaa
     1261 gatgtgggcg gtcaaatcag tggcctttca aatagactta caagcagtga gcaaggaacc
     1321 actactcaga tttcaaatct ttcaaatcgg ataaacagta ataaacaagg cgcagataat
     1381 cagatttcaa atttaaagac tcaggtcgct acaaacaagg ataatgctga acgacaaatg
     1441 ggtagaatat ctgatcaggt ttctgcaaac aaagcgaatg ctgatagtca atttgcgaat
     1501 gtgaccaatc aactagtgcg aaaagtagag actactgact tccagcgtgt taaggaaacc
     1561 agtaaacttt acgagcggat tttgggcaat actgaaaatg gaattgcgga taaggttgct
     1621 cgcatggctc tgaccaatca actgtttcag gttgaggttg ggaaatatag tgtaagcggc
     1681 cctaacctca ttaagaatag tgattttaaa aatggtacga atgaatgggg ctcaactcaa
     1741 aatttaggaa gattggttaa gcatagcttt tatcacaacg ggcagaaaga ccttatgcgt
     1801 ttaagtaatg caactaaaaa cgaaaacttt ttgtatagtc accgttttaa tcttgaacga
     1861 aatactgact atgtactgaa ttttagagga tttaacaaca gtgctctagc aagctatgat
     1921 gtttatattt tgggacgaag agcaggcgag agcgatggat tcacaatcgt taagaaagtt
     1981 gttagcagca agaaactatc tacctctaga tgcgaagatg tctcagtaac ttttaattcc
     2041 ggagaaatgg ataatgctta cattcgtttt gataacaatg gctcatcatc aggaacagct
     2101 gatttgtata ttacagaagt tgacttgtac aaaggttata aatctagaac atggcaacca
     2161 catccagaag atgcagtcgc agatgcgaat aagaagcttg aagcaacgca aacaaaaatg
     2221 actcaactag ctggctcatg ggtagttgaa aacatcaact cggctggaga tatcatctct
     2281 ggaatcaatc ttggcgccaa tggacataac cgcttagttg ggaaattgac ccacatcact
     2341 ggagagaccc tgattgacag agcagtcatc aagtctgcca tggttgataa gctcaaaacg
     2401 gccaattttg aagctggttc ggtcacgact acgatattag aagctgaagc ggtaactgct
     2461 gagaagttga aagttgacga tgcgcttatt agaaaattaa ctgcaaaaga tgcttttatt
     2521 gaccgactga catctaaacg tatcttctct attaaggttg agtccgtcat ttctagctca
     2581 accttcctag aagcctatca aggccgaatt ggtggattca cacttggtca atttgaccag
     2641 ggtggcggtc gctggatttc aggtgtcaat cagttctctg ttggtatggg gaatggtgcc
     2701 gggcatggag tccggacagc cttctgggcg aactggggaa ataattggaa ctatgccgga
     2761 cctaaagcat ggaacgtcaa tactgatggg aaaatgtact gtaggaatga agtcggtttt
     2821 tatgatcaag tggatttttc gaattcatcg agagcaaact tctatgggaa tactactttt
     2881 tctcgttctc ctgtgttttc aaatggtatc gaacttggaa gtaaagatgt gcttggtgat
     2941 ggttggaatc ccaaaggcgg aaggaatgca gttgtttggt ggaatcaggt cggtagcggt
     3001 agcgtgaagt attggatgga acaaaaatca gacagacgct taaaagagaa catcacagat
     3061 acagctgtga aagccttgga caaaatcaac agattaagaa tggttgcatt tgatttcatc
     3121 gaaaataaga aacatgagga gattggtcta atagctcaag aggctgaaac catcgttcca
     3181 agaattgtct cacgagatcc tgagaatcca gatggctatc tacatatcga ctataccgct
     3241 ttagttcctt acttaatcaa ggctattcaa gaattaaatc aaaaaataga aaaaatggag
     3301 aaaacaatag catgaataac aacatgttga ccaatatcgc acttaaagca attcaggagc
     3361 ttgctcttga aaatagaaaa cgaacacaca gattggagaa cttagaaaat gaacacagaa
     3421 cagcttaacc aagccttacg aatgacaatt agtgaaatat caacaacttc aacaaattcg
     3481 atgattacaa gtaatatctt gagtattcag ttggatgagc aaagggaaga aaatcaaaga
     3541 cttcaagcac gagtggatga gctggaagct ctgcttgatg aacaaactaa accagcagac
     3601 aaaggagaat agacatggca gaaacaattc aaaacacaga taacttacta gaccttacaa
     3661 aaatcacaga accatttgat cttgcgagtg ctttgcgcta catgaaagaa aatggagagt
     3721 tcattcgttg caagaatgta agcgatgact tctatatgta tcgtgacgtt caaaaacgtc
     3781 ctgtgattgt aaatggccgt cgccaattca aggatgttga aaccgtttgg gcgttcaatc
     3841 agtggggtgg tacaatcgca acaatcaacg tagccgttct gttgaatcat gaattctata
     3901 tcatgaaatt tgatgcagag ggcaatcctg actggacggt tccaacggta gaacctaaag
     3961 aataggaggt tgtatgcaaa ttgaattttt caattttcta agaagtgtcg tacagactga
     4021 agatggtttg gtattgtacg ctctagcact gattgtctca atggaaatca ttgattttgt
     4081 gacagggacg attgcggcaa ttatcaatcc tgacatcgag tacaagagca aaatcggcat
     4141 taacgggctc cttcgtaaga tttcaggggt tctcttactg atgatcctca ttccggcgtc
     4201 cgttttgttg cctgaaaaga caggttttgc attcttgtac tcaatctatc tcgggtacat
     4261 cgcatttact tttcaatctc tcattgaaaa ttaccgcaaa ttaaaaggaa atgttactct
     4321 ttttcagccg attgtaaaag tatttcagcg attacttgaa aaagatgatg atacgaaaaa
     4381 aggagaataa caaatgcaac aaattactga aatcattact aatggagcaa tcagcatcct
     4441 tgttattttg gcaggggttg tagttagggc agtcaaggaa tacctcgtca aaaaaggtgg
     4501 agaaaagact atcaagattg ttgaaatctt ggccaaaaat gcagtaaatg ccgtggagca
     4561 ggtagctgct gaaactggct acaagagaga tgaaaaactg gcacaggctc gcgctaaagt
     4621 ccgtgctgag cttacaaaat acaatattag catgactgac aaagacttag acaccttcgt
     4681 agagtcagca gtgaagcaga tgaatgacgc atggaaagga cgataggata gggaatggat
     4741 atcgatagaa acagactacg aacaggcttg ccccaggttg gggtgcagcc ttatcgacaa
     4801 gtacacgccc actcaacagg caaccgtaac tcaacagctc aaaatgaggc tgattaccac
     4861 tggcggaaag acccagaatt aggttttttc tcgcacgttg tcggaaatgg ccgtgtcatg
     4921 caggtaggac ctgtgaacaa cggaagttgg gatgttgggg gcggttggaa tgctgagacc
     4981 tatgcagcgg ttgaactgat tgaaagccat tcaactaagg aagagtttat ggctgactat
     5041 cgcctctata tcgaattgct acgcaatcta gcagatgaag caggcttgcc gaaaacgctt
     5101 gatacaggga gtttagctgg aattaaaacg cacgagtatt gcacgaataa ccaaccaaac
     5161 aaccactcag accacgttga cccttatcct tatcttgcaa gttggggcat tagccgtgaa
     5221 cagtttaagc aagacatcga aaacggcttg agcgctgcaa caggctggca gaaaaatggc
     5281 actggctact ggtacgtaca ctcagacggc tcttatccaa aagataagtt tgagaaaatc
     5341 aacggtacct ggtattattt cgatggctca ggctatatgc tttcagaccg ctggaagaag
     5401 cacacagacg gcaactggta ctggttcgac aactcaggcg aaatggctac aggctggaag
     5461 aaaatcgctg acaagtggta ctattttgat gtagaaggtg ccatgaagac aggctgggtc
     5521 aagtacaagg acacttggta ctacttagac gctaaagaag gtgccatggt atcaaatgcc
     5581 tttatccagt cagcggacgg aacaggctgg tactacctca aaccagacgg aacgatggca
     5641 gataaaccag agttcacagt agagccagat ggcttgatta cagtaaaata aatagaaagg
     5701 aaactttcta aattgttctt tcaccgcagg ctcaggcttg cggtttttta tttgctctga
     5761 tttttcaaaa aagtgcttac ttgaagaata gggaggtgtt ttgtcaaaaa taaaaacagt
     5821 gaccgaaatc actgcttatc agttgtagca aattcataaa gtttttctgc tgtgagaagt
     5881 gccattttgt ccatgcttgt ttttcctttt ctgaggtcag aaacagtagt ccatggaact
     5941 ccagcacctt gggaaatagc agatgtagac atcgaactgt ctaacaattc ttgaataact
     6001 tctctcatct tatttgtcct ttttattttt tagataaata tatacattga ttgcaattat
     6061 aaaaatagct attgcactaa ccattgcatt tcctctttcc atttgataaa atagaggtgt
     6121 gaggggcttt cgccccaacc tcttagcgtt cacctttttc tttgacggga tttcggttta
     6181 cgctttttgt tttgccttgc gaccgttatt gcagtcacca gacttgctat agcagttacc
     6241 gtttcaggga tattatctat cgccttttcc agtaacctaa gccaatcttc tttgttcaac
     6301 ttcctcacct cctttcctta tcttgattat attatatcac g
//
LOCUS       DBERCW010000066         6180 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.066, whole genome shotgun sequence.
ACCESSION   DBERCW010000066 DBERCW010000000
VERSION     DBERCW010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.066"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(185..550)
                     /locus_tag="ACL72M_002032"
                     /pseudo
     CDS             complement(185..550)
                     /locus_tag="ACL72M_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
     gene            570..737
                     /locus_tag="ACL72M_002033"
     CDS             570..737
                     /locus_tag="ACL72M_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HGS0717089.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(892..1095)
                     /locus_tag="ACL72M_002034"
     CDS             complement(892..1095)
                     /locus_tag="ACL72M_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717090.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(1118..1309)
                     /locus_tag="ACL72M_002035"
     CDS             complement(1118..1309)
                     /locus_tag="ACL72M_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGS0717091.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            1880..2248
                     /locus_tag="ACL72M_002036"
     CDS             1880..2248
                     /locus_tag="ACL72M_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0717092.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            2248..2481
                     /locus_tag="ACL72M_002037"
     CDS             2248..2481
                     /locus_tag="ACL72M_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717093.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            2481..2744
                     /locus_tag="ACL72M_002038"
     CDS             2481..2744
                     /locus_tag="ACL72M_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGS0717094.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            2757..3137
                     /locus_tag="ACL72M_002039"
     CDS             2757..3137
                     /locus_tag="ACL72M_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGS0717095.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            3154..4224
                     /locus_tag="ACL72M_002040"
     CDS             3154..4224
                     /locus_tag="ACL72M_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGS0717096.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            4285..4632
                     /locus_tag="ACL72M_002041"
     CDS             4285..4632
                     /locus_tag="ACL72M_002041"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717097.1"
                     /translation="MEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAAIL
                     LQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIEGD
                     YLVRNLIDVYYKK"
     gene            4722..5420
                     /locus_tag="ACL72M_002042"
     CDS             4722..5420
                     /locus_tag="ACL72M_002042"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0717098.1"
                     /translation="MNYIDTNEMLFVETPRKVITSDELRKKNTKYLDQKEFKLFIQNL
                     KDEALCDYRITKYIRIAKVLFLTGMRYGELAALNYKEDIDFSKKTIHIKHTYDFRQKE
                     RTTPKTIKSDRVITAPQKVLDIIKEQIIENATNGFDTDFIFINTLGEPITNARVICAL
                     KRHGQKIGIEKNITTHTFRHSHISLLAELGIPLTAIMDRVGHSDSKTTLEIYSHVTQK
                     MVSDISSKLDKIKF"
     gene            complement(5503..5596)
                     /gene="ffs"
                     /locus_tag="ACL72M_002043"
     ncRNA           complement(5503..5596)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL72M_002043"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5629..6096)
                     /gene="tadA"
                     /locus_tag="ACL72M_002044"
     CDS             complement(5629..6096)
                     /gene="tadA"
                     /locus_tag="ACL72M_002044"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGS0717099.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
BASE COUNT         2128 a         1286 c         1017 g         1749 t
ORIGIN      
        1 tttttgacaa taatcaaaaa ataaaaagga gctattatta acaaaatggc gtttttggca
       61 ataataccct gccattcctc ctccctattc ttcaagaaaa cgcttttttg aagaatcaga
      121 gcaaataaaa aaccgcaagc ctgagcctgc ggtgaaagaa caatttagaa agtttccttt
      181 ctatttattt aactgtaatc aagccatctg gctctactgt gaactctggc ttgtctgcca
      241 gtgttccgtc tggtttgagg tagtaccagc ctgttccgtc cgctgactgg ataaaggcat
      301 ttgataccat ggcgccttct ttagcgtcta agtagtacca agtgtccttg tacttgaccc
      361 agcctgtctt catggcacct tctacatcaa aatagtacca cttgtcagcg attttcttcc
      421 agcctgtggc catttcgcct gattggtcaa agtagtacca attaccgtct gtgtgcttct
      481 tccagcggtc tgaaagcata tagcctgagc catcgaaata ataccagata ccgttgattt
      541 tctcaaactt atagaaagga ggagatagta tggcaaatac tccaataaaa cctggaacag
      601 ataatcagaa acctggtcgc tatgtagagg taggacctcg tggcggaaaa gttactaatg
      661 gtcataccgc aactatcgga aaaggtgatc ggctccctcc gacatctgct aaaggcaacg
      721 gttggaaaaa agtctaatct tcgtttgcgt acaatcgttc aatggttgta cgctttttcc
      781 atacacaaaa gcacattccc aaaaaatcaa tttgaatcca tgcttcggcg taatctttcc
      841 cattgctggc atagtgagtt atataatggt gaatcatttt attccttcct cctattgagt
      901 tacttgagaa gtatcatgaa tggcttcata gctaagacgc ttaaattctt ctgagtctat
      961 ctgaaaattg ataggctttt tttgtaaaca ctcaagaaaa ctagtgtttc ttaaaagttt
     1021 ttcaactaac tcagggtctg cctttacaaa ggtggactct ttttgtccac tatacggata
     1081 tcgttttggt ctcattttcc tactcctcaa atctttccta ctcaatccca taatcttcaa
     1141 taacctgaag aatgaaactg ttcgctcgtg gacctttagt cgttccactt agaatgtttg
     1201 tcacttcctg tcgtttaaag ccgtaagcaa ccgctagagt tgctttttta atgcctttct
     1261 ctttcaagaa agcaataact ctttcgcgac cgtttgcgat atctggcata ttttctcctt
     1321 tctttttctt tcttcttttt ctgctataat ataagcagaa aggagttaac cttatgactt
     1381 ttaaagaata tttactcaaa gcaagcaaac gcgacatcta cgatgatggt aaagattttg
     1441 agaaatcaat ttcagattct cactaatcga gcgtgacttt tttgatatgg caatctcaga
     1501 aatttaccac cagcgctgac taccttaatg actttttcaa ggtggtcttt ttcttgttct
     1561 aaatttttaa gaatacttac catcagcacg ttcctcctct ttacttattt gtaaataaga
     1621 aacaactaaa aatgtaacta tttttctgca ttatacttga caacttacac caaatcggct
     1681 aaaattaaag cataataaaa acaccaataa atctataaat accgttcgcc aaaacatttt
     1741 tataatttat ttcttagttg tttttttagt tgtttatcac ttacaaaaaa cattttacac
     1801 cttttgggat aattagtcaa cctttttaca ccaaatttgt taaatttttt tgtgatgtct
     1861 tagaaaggtt gatttaacaa tgtttgagac atttgaaaaa ataaaagaat tggcaaaaaa
     1921 gcgtggaaaa gctcttggac aagtagaaga agacttaggt tatggtagaa atacactcta
     1981 taagataaaa aattctacgc caaacgctga acgtatcgca gaaattgcta attatttcaa
     2041 cgtatccacc gactacctgc tcggacgaac agataaccct gctatcgctg ggagtgatga
     2101 atttgcccaa gtaaacggac aaatcataga cttacgcaaa gcagcagcca acaccatgtt
     2161 atttgacggg aaaccactaa atgaagatga tatcgacttc attacatccg tcctatccgc
     2221 ccacttcaaa agcaaaggag aacgctaatg actatcacta tcaacttcac agaaaaaaat
     2281 tcctacatta cggactacct aaacaaacac ggtatcgaca caacgaccat ggattttgac
     2341 gacttcatgg cactcatgga agatatcgaa gacgcacgag cagccgacca agcctatatg
     2401 gagtatttag ccgacccagc tacttatacc atggatgagg tcttggatga actaggacta
     2461 actcgagagg atattgctta atgtatcggc tagatattga taaaaaagct ctcaagcaac
     2521 ttaaaaaact agatacccca accagaaaac aaatcctatc ctggcttgct aaaaacattg
     2581 aaaacacgac caatccacga caacacggaa aagcactaaa agccaacctt gcaggttact
     2641 ggcgatacag agtagagaat taccgcatca tctgtgatat ccaagacgat aaactagtcg
     2701 tcctagccgt ggaaatcgcc caccgcagag atgtctataa ataacgaagg agaactatga
     2761 cactcgctaa actctgcgaa gaatatcaag tagaactttg tctcttcgac ggttcaaact
     2821 ggcacaatag cggtttctac aatccagaca caaacgtgct cgctattgac cacaacttga
     2881 ctcctgaaca acaaatccaa gtcgccctac acgaacttgg acacaaagac cacacacgct
     2941 cagagcacca gaacgcccgt ctacgctgtg aaaacgaagc tgataggaat atgatccatc
     3001 atctcgtaaa agacgctcta gaaaacttag acgaccccac agagtttgat tacctcaaat
     3061 tcatgtctta ctacaatcta aaaaccatga caaatgaaat catggttaaa gaagagtatt
     3121 tagcattagt aaattaaaaa aaggagtatc aatatggaaa ttgataaagt aaaagccgat
     3181 ttaaaacaag tcggcaaacg tgtagcagac ctcagccaaa gcattacgaa tgaagaacaa
     3241 acaaagaatg ccttcattat gccgttcttc caagcgcttg gatatgatat cttcaatcca
     3301 cttgaatttg tcccggaatt tactgccgac gtgggcatta aaaaaggcga aaaagtcgac
     3361 tatgcgatca ttttggatgg cgagcctcaa atcctaattg aatgtaaatc aattacagaa
     3421 aaccttacta agcacgactc tcaactattc agatatttcg taactactaa atcaaaattc
     3481 ggtatcttga caaatggtag agaatataaa ttctttactg atttagatga gccaaataaa
     3541 atggacacaa ctccattctt aacaatcgat gtgactgata tcaaagaaaa tcaatttact
     3601 gaaatcatca aattccacaa agagaatttt gatattgata atattgtttc atcagcttct
     3661 gaattgaaat acctcaacaa tcttaaagcg ttccttactg aaaatatcac tacaccgtca
     3721 gatagcttcc tcagatatct aacttctgaa atctatgaag ggcgtgttac tcaaaatatc
     3781 ttaacgacat tttctcccat tattgtgaaa gggtttaatc aattcatcac agagcgagtt
     3841 aatgaaaaat taagtgctgc acttaataca agcgttgaaa ccaaagtaac aaccgatatt
     3901 ccaaaagttg aagctgaagc tgaagagatt gtcgaagtaa ctgacgaaat tatcacaact
     3961 cctgctgaat tagaagttta tactgttgtt aaaatgcttg ctagggatgt agtttctcca
     4021 gaacgtgtat tttacagaga taaccgtagc tatttcaatg ttttggttga cgataacatc
     4081 aaaaaatggg tattacgtta tcgttcaaat tcaaaaaaaa gcactatcga aatccgtgat
     4141 aaaggcatct tcccggtgtc tacccctctc gaagtcgcaa attatgccaa tgaaatttta
     4201 gaagtaatca agaaattctc ataataaaaa aagccctctt tactataccc attttatcaa
     4261 aaaagtgagg taaaatcaat gtggatggaa gaattgccaa acggcaaata taaatttttt
     4321 gagagataca aagatccata tactgagaaa ttaaaaaaag tctcagtaac gatggagaaa
     4381 aaaactcccc aagcaagaaa tcaagctgcg attttacttc aggaaaagat aaaacaaaag
     4441 ttaggagaaa aacaacattc tgtttctaat ataacttttg aaaaactata tgaagaattt
     4501 gaggagaatt ggaaacacgg cgtaaaaaac tcaaccgtct acgcttcaaa gaatgtaaaa
     4561 aaagagattt taaagcagat agagggcgac tacctagtta gaaatttgat agacgtttat
     4621 tacaaaaagt aatagatcaa ctattacaag atgggagatc tcataactat gtttctaaaa
     4681 tcaaattcaa gctcaatcag ataatgaaat ttgctatcag aatgaattat attgatacaa
     4741 atgaaatgct atttgttgaa acgcctagaa aagtaattac atccgacgaa ctcagaaaga
     4801 aaaatacaaa atacttagac caaaaagagt ttaagttatt catccaaaat ttaaaagacg
     4861 aggccctatg tgattatcga attacaaagt atatccgaat agctaaagtt ctttttctta
     4921 ctggcatgag gtatggagag ctggcagcct taaactacaa ggaagatata gatttttcta
     4981 aaaagactat tcacatcaag catacatacg atttcagaca aaaagagaga actacaccaa
     5041 agacaatcaa gtccgatagg gttataacag cacctcaaaa agtgttagat attatcaaag
     5101 agcaaataat agagaatgcg acaaatggat ttgatacaga ttttattttc atcaatactc
     5161 taggagaacc aataacaaat gccagggtta tttgtgcatt gaaaagacat ggtcaaaaaa
     5221 tcggcataga aaaaaacata actacacata catttagaca ttctcacata tccctacttg
     5281 ctgagctggg cattcccttg actgccatca tggacagagt agggcatagt gactcaaaga
     5341 ccacactaga gatttattct cacgttactc aaaaaatggt atcagacata tctagcaagt
     5401 tagacaagat aaaattttaa attgtgcccc tcgtctgccc ctttttctta tacaagacaa
     5461 acaaaaaccc cttaaagtgt tgattttaaa gggtttttaa agtgcacgaa aaaagagcac
     5521 acaattcaaa tcgcttaggg ctgctggatt cctcccctga cccgcttcac gcagaactgt
     5581 tgctccacta tttattatat cacattccta ttcattttaa aagcaaaatt attttttccg
     5641 tctatttcta aaaaaatcct gcatgatagc tgcgcattca tcttccaaaa ttcctatttc
     5701 aacctccaca cgatgattga gacgctcatc tgtcaagata tcgtacaaac tcccagcagc
     5761 gccaaatttc tggtttttag ccccatagac cacatttgga atgcgggcaa gcccaatcgc
     5821 cccactacac atgacacaag gttcaatggt cacaaaaagt gtgcaatcca gcaagcgcca
     5881 gctctcctca ctcaagttcg catcctctat agccataatt tccgcatgca taaccgctcg
     5941 ctgtaattcc tcacgcgcat tatgcccacg accaatgatt tccccatctt tgacaatcac
     6001 acaaccaatt ggaatttcat cgtgttcaag agcaatctca gcctctctca aagcctccct
     6061 cataaagact tctttttctt caagcgtata atacatctct tttctctttt cctacttatc
     6121 gattttatta ttatatcatg aatcccaaca caaaagaagc caccgaatgc ggtgactcta
//
LOCUS       DBERCW010000067         5055 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.067, whole genome shotgun sequence.
ACCESSION   DBERCW010000067 DBERCW010000000
VERSION     DBERCW010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.067"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            185..1730
                     /locus_tag="ACL72M_002045"
     rRNA            185..1730
                     /locus_tag="ACL72M_002045"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1782..1854
                     /locus_tag="ACL72M_002046"
     tRNA            1782..1854
                     /locus_tag="ACL72M_002046"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1815..1817,aa:Ala,seq:tgc)
     gene            1979..4880
                     /locus_tag="ACL72M_002047"
     rRNA            1979..4880
                     /locus_tag="ACL72M_002047"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4957..>5055
                     /gene="rrf"
                     /locus_tag="ACL72M_002048"
     rRNA            4957..>5055
                     /gene="rrf"
                     /locus_tag="ACL72M_002048"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1425 a         1024 c         1487 g         1119 t
ORIGIN      
        1 gttgacaagt gaaagtggct gtgatatact aatatagttg tcgcttgaga gaagcaagtg
       61 acaaagacct ttgaaaactg aacaagacga accaatgtgc agggcgctac aacataagtt
      121 gtagtactga acaatgaaaa aacaataaat ctgtcagtga cagaaatgag taagaactca
      181 aacttttaat gagagtttga tcctggctca ggacgaacgc tggcggcgtg cctaatacat
      241 gcaagtagaa cgctgaagga ggagcttgct tctctggatg agttgcgaac gggtgagtaa
      301 cgcgtaggta acctgcctgg tagcggggga taactattgg aaacgatagc taataccgca
      361 taagagtaga tgttgcatga catttgctta aaaggtgcac ttgcatcact accagatgga
      421 cctgcgttgt attagctagt tggtggggta agggctcacc aaggcgacga tacatagccg
      481 acctgagagg gtgatcggcc acactgggac tgagacacgg cccagactcc tacgggaggc
      541 agcagtaggg aatcttcggc aatggacgga agtctgaccg agcaacgccg cgtgagtgaa
      601 gaaggttttc ggatcgtaaa gctctgttgt aagagaagaa cgagtgtgag agtggaaagt
      661 tcacactgtg acggtatctt accagaaagg gacggctaac tacgtgccag cagccgcggt
      721 aatacgtagg tcccgagcgt tgtccggatt tattgggcgt aaagcgagcg caggcggtta
      781 gataagtctg aagttaaagg ctgtggctta accatagtag gctttggaaa ctgtttaact
      841 tgagtgcaag aggggagagt ggaattccat gtgtagcggt gaaatgcgta gatatatgga
      901 ggaacaccgg tggcgaaagc ggctctctgg cttgtaactg acgctgaggc tcgaaagcgt
      961 ggggagcaaa caggattaga taccctggta gtccacgctg taaacgatga gtgctaggtg
     1021 ttagaccctt tccggggttt agtgccgtag ctaacgcatt aagcactccg cctggggagt
     1081 acgaccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagcg gtggagcatg
     1141 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccct ctgaccgctc
     1201 tagagataga gttttccttc gggacagagg tgacaggtgg tgcatggttg tcgtcagctc
     1261 gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccctattgt tagttgccat
     1321 catttagttg ggcactctag cgagactgcc ggtaataaac cggaggaagg tggggatgac
     1381 gtcaaatcat catgcccctt atgacctggg ctacacacgt gctacaatgg ctggtacaac
     1441 gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc agtctcagtt cggattgtag
     1501 gctgcaactc gcctacatga agtcggaatc gctagtaatc gcggatcagc acgccgcggt
     1561 gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgagagttt gtaacacccg
     1621 aagtcggtga ggtaaccgta aggagccagc cgcctaaggt gggatagatg attggggtga
     1681 agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggataa
     1741 ggaactgcgc attggtcttg tttagtcttg agaggtcttg tggggcctta gctcagctgg
     1801 gagagcgcct gctttgcacg caggaggtca gcggttcgat cccgctaggc tccattggtg
     1861 agagatcacc aagtaatgca cattgaaaat tgaatatcta tatcaaatag taacaagaaa
     1921 ataaaccgaa aacgctgtag tattaataag agtttatgac tgaaaggtca gaaaataagg
     1981 ttaagttaat aagggcgcac ggtggatgcc ttggcactag gagccgacga aggacgtgac
     2041 aaacgacgat atgccttggg tagctgtaag taagcgatga tccagggatt tccgaatggg
     2101 ggaacccaac aggtaatacc tgttacctac atctgttaag gatgtgagga ggaagacgca
     2161 gtgaactgaa acatctaagt agctgcagga agagaaagca aaagcgattg ccttagtagc
     2221 ggcgagcgaa acggcagaag ggcaaaccga agagtttact cttcggggtt gtaggactgc
     2281 aatgtggact caaagattat agaagaatga tttgggaaga tcagccaaag agagtaatag
     2341 cctcgtattt aaaatagtct ttgtacttag cagtatcctg agtacggcgg gacacgtgaa
     2401 atcccgtcgg aatctgggag gaccatctcc caaccctaaa tactccctag tgaccgatag
     2461 tgaaccagta ccgtgaggga aaggtgaaaa gcaccccggg aggggagtga aatagaacct
     2521 gaaaccgtgt gcctacaaca agttcgagcc cgttaatggg tgagagcgtg ccttttgtag
     2581 aatgaaccgg cgagttacgt tatgatgcga ggttaagttg aagagacgga gccgtaggga
     2641 aaccgagtct gaatagggcg ccttagtatc atgacgtaga cccgaaacca tgtgacctac
     2701 ccatgagcag gttgaaggtg cggtaagacg cactggagga ccgaaccagg gcacgttgaa
     2761 aagtgcttgg atgacttgtg ggtagcggag aaattccaaa cgaacttgga gatagctggt
     2821 tctctccgaa atagctttag ggctagcgtc gacattagag attcttggag gtagagcact
     2881 gtttgggtga ggggtccatc ccggattacc aatctcagat aaactccgaa tgccaatgaa
     2941 ttatggtcgg cagtcagact gcgagtgcta agatccgtag tcgaaaggga aacagcccag
     3001 accaccagct aaggtcccaa aataattgtt aagtggaaaa ggatgtgggg ttgcacagac
     3061 aactaggatg ttagcttaga agcagctatt cattcaaaga gtgcgtaata gctcactagt
     3121 cgagtgaccc tgcgccgaaa atgtaccggg gctaaaacaa tttaccgaag ctgtggatac
     3181 ctttataggt atggtaggag agcgttctat gtgtgatgaa ggtataccgt gaggagtgct
     3241 ggaacgcata gaagtgagaa tgccggtatg agtagcgaaa gacaggtgag aatcctgtcc
     3301 accgtaagac taaggtttcc aggggaaggc tcgtccgccc tgggttagtc gggacctaag
     3361 gagagaccga aaggtgtatc cgatggacaa caggttgata ttcctgtact agagtatgta
     3421 gtgatggagg gacgcagtag gctaactaaa gcagacgatt ggaagagtct gtctaagcag
     3481 tgaggtgtga attgagtcaa atgcttaatt ctataacatt gagctgtgat ggggagcgaa
     3541 gtttagtagc gaagttagtg acgtcacact gccaagaaaa gcttctagcg tttaaacata
     3601 ctctacccgt accgcaaacc gacacaggta gtcgaggcga gtagcctcag gtgagcgaga
     3661 gaactctcgt taaggaactc ggcaaaatga ccccgtaact tcgggagaag gggtgctgac
     3721 ttaaagtcag ccgcagtgaa taggcccaag caactgttta tcaaaaacac agctctctgc
     3781 taaatcgtaa gatgatgtat agggggtgac gcctgcccgg tgctggaagg ttaagaggag
     3841 tgcttagcgt aagcgaaggt atgaattgaa gccccagtaa acggcggccg taactataac
     3901 ggtcctaagg tagcgaaatt ccttgtcggg taagttccga cccgcacgaa aggcgtaatg
     3961 atttgggcac tgtctcaacg agagactcgg tgaaatttta gtacctgtga agatgcaggt
     4021 tacccgcgac aggacggaaa gaccccatgg agctttactg cagtttgata ttgagtgtct
     4081 gtaccacatg tacaggatag gtaggagtct aagagatcgg gacgccagtt tcgaaggaga
     4141 cgctgttggg atactaccct tgtgttatgg ccactctaac ccagataggt gatccctatc
     4201 ggagacagtg tctgacgggc agtttgactg gggcggtcgc ctcctaaaag gtaacggagg
     4261 cgcccaaagg ttccctcaga atggttggaa atcattcgca gagtgtaaag gtataaggga
     4321 gcttgactgc gagagctaca actcgagcag ggacgaaagt cgggcttagt gatccggtgg
     4381 ttccgtatgg aagggccatc gctcaacgga taaaagctac cctggggata acaggcttat
     4441 ctcccccaag agttcacatc gacggggagg tttggcacct cgatgtcggc tcgtcgcatc
     4501 ctggggctgt agtcggtccc aagggttggg ctgttcgccc attaaagcgg cacgcgagct
     4561 gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc gcgggcgtag gaaatttgag
     4621 aggatctgct cctagtacga gaggaccaga gtggacttac cgctggtgta ccagttgtct
     4681 tgccaaaggc atcgctgggt agctatgtag ggaagggata aacgctgaaa gcatctaagt
     4741 gtgaaaccca cctcaagatg agatttccca tgattatata tcagtaagag ccctgagaga
     4801 tgatcaggta gataggttag aagtggaagt gtggcgacac atgtagcgga ctaatactaa
     4861 tagctcgagg acttatccaa agtaactgag aatatgaaag cgaacggttt tcttaagttg
     4921 aatagatatt caattttgag taggtattac tcagagttaa gtgacgatag cctaggagat
     4981 acacctgtac ccatgccgaa cacagaagtt aagccctaga acgccggaag tagttggggg
     5041 ttgccccctg tgaga
//
LOCUS       DBERCW010000068         4738 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.068, whole genome shotgun sequence.
ACCESSION   DBERCW010000068 DBERCW010000000
VERSION     DBERCW010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.068"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(181..1929)
                     /locus_tag="ACL72M_002049"
     CDS             complement(181..1929)
                     /locus_tag="ACL72M_002049"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0717100.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDTFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1931..3655)
                     /locus_tag="ACL72M_002050"
     CDS             complement(1931..3655)
                     /locus_tag="ACL72M_002050"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0717101.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPIDKGSIDL
                     YRDGSSPRNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3713..4651)
                     /gene="msrB"
                     /locus_tag="ACL72M_002051"
     CDS             complement(3713..4651)
                     /gene="msrB"
                     /locus_tag="ACL72M_002051"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS0717102.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
BASE COUNT         1409 a         1038 c          982 g         1309 t
ORIGIN      
        1 ctgacttcgt cagtcttatc tacaacctca aagctgtgct ttgagcaacc tacggctagc
       61 ttcctagttt gctctttgat tttcattgag tattacagtg aacaattttt ctagctattg
      121 taacaaaaaa gtcactcgaa ggcaactttt ttcgtccata aactttcaaa agagaatggc
      181 ttattcagaa ctaaaagccg cagctttttg catttggtaa tacttaccct ttctatccat
      241 gagttcttga tggttaccat attcaacaat atcaccatct actaagacaa gaattaaatc
      301 cgcatcctga atggttgaca aacggtgagc aatgatgaag cttgtgcggc ccttcatgag
      361 ttttgcaaag gtatcctgta ccagcacttc tgtccgtgta tcaatggaag aagttgcctc
      421 gtctaagata agaatctttg gaatagccag aaagactcgg gctatggtca agagctgagc
      481 ttggccgaca gagagagatt ctccagcatt ttccaacttg gtatcgtatc cctgtggcaa
      541 ctgttgaatg aaaaagtctg cattagctgc tttggcagca gcaattactt gctctcgact
      601 ggcttcagga ttgccaaagg caatattatc atgaatggtc ccttgtgtga gccaggtttc
      661 ttgaagcacc ataccaaact gctgtctcaa tgatgctcgt gtataatcat aaatggattg
      721 cccatccagc aagatatctc ccgagctaat gggataaaaa cgcataagga gattgataag
      781 agttgatttt ccagcacctg tcggaccaac gatggctatc ttactaccag ctggaatatc
      841 gatagacaag tccttaatca aaattttttc aggatggtag ccaaaagaga catgtttaaa
      901 ggaaatagct cccttaactt ggtcactggt caagacttcc ttacctgttt cagccacttc
      961 agggctatct aagactccat agatacgctc tacgcaagcc agagcacttt gcaactcagc
     1021 tagcactgaa gaaatatcgt taaagggctt ggtgtattgc tgaacatagt tcaaaaaagt
     1081 cactaaacga ccgacggtca aggctgaacc catcatgata cgataagctc ctactccagc
     1141 taaaagggca taaatgagtg catttacaaa gcgagtcgaa ggattgaccg ttgaagaata
     1201 aaagatggct gactgagaat agcctgagta gttgtcatga gcctcacgca atctttggat
     1261 aaattctgtt tgagcattga aggactggat tatagtctgc tggctaagcg attcttcaat
     1321 caactgagtc tgaattcccc tcgtctctgt ttgcttctgg aagagatgat aggatctctt
     1381 ggcaataaag cgtgaaatca ccatggacag tggcgtcaac agcaagacta agagagtcat
     1441 gaggagatga atttggagca tggctagaat actaaccaaa atcatcaaaa caccaatgaa
     1501 aaattggtta aaaatcatgg tcaagccagc tgccaactgt tcgatgtccg tggttacacg
     1561 actgaccatc tctccattgc cttgccgatc cgcaaaagca atcggtaacc gatggagttt
     1621 atggatgatt cgctctcgta aatctctggt ataagagaag attagacgat tatagaggag
     1681 aggattggcc cattgtacta gagtatttcc tattaccacc aagagcatct ggagaaaaat
     1741 ctgccaaaaa actggtgatg aaccagccac taggacttgg tcaatgacct gcccaatcag
     1801 aataggtaga taaattgata agccaacttg ggcaatagtt cctagaaagg ctaggaaaag
     1861 gaggaaggga tggtttgcta aatctacggc taaacgtttg agcgtctggt ttacagtttg
     1921 tcgtttcatt ctagtcctcc tttccatgtt gggatgcatt gatttcacga tagacttgac
     1981 tggatttcat caagtcatcg tgcttgccaa cagctagcaa ctcacctttt tccaagagga
     2041 gaatctggtc agccatctgt aaagtcgagg ttcgttgaga gatcaaaatt aagctcatgt
     2101 ttggaaaatt ttctctaata gctttcaaga gcttggactc ggtaatggtg tccagtgctg
     2161 aggtcgcatc atctaggatg agaaacggag cctggcgcaa gactgctcgt gcgatagaca
     2221 gcctttgttt ttgtccacct gagaaatttc gccctcctgc ttcaactaga gcatccaaga
     2281 gtccttcctt atcactgaca aaatccttag cttgagcaat ttccaaggct tgccagagtt
     2341 cttgatcagt cacttcttga tttaaaccta aagtcaagtt ggaacgaata gttcccttaa
     2401 aaagttcgac cttttgggga acataagcaa tccaagaccg ccactgctct aaattacgag
     2461 gactagatcc atctcgataa aggtcaatgc tccccttatc tattggataa agtccaagta
     2521 agagttgcac caagcttgac ttaccagaac ccgttccccc gatgatacct agaatttgtc
     2581 cttgagtcat atcaaaggaa atgtatctca gagaaggctg ggccgcatca ggataggtaa
     2641 aagtcaattc ttggacttgt aaaacccgac cactggtaac ttgcttttgt tctaattctg
     2701 aatggatgtt ttcgggagat tccgcaaaga cctcctcgat tcgcttggct gagatatagg
     2761 actggttgag agaatttatc aacatggcta gcttgaccaa ttccaccaaa atctgtaaga
     2821 ggtaattgat aagagcaatg agagcacctt gactgagcac tcctccttga attgaaatat
     2881 agccttgcca gataataacg agaagagttc cattgacaat cagataggtc agaggtgtta
     2941 ataaactaga ccagaaacct gtcttttctt gtaatctagc ataaacttgg ttaagggttt
     3001 gaaaaatctg taactctcgt ttttcttgac caaaagcacg aataacccgc atcccttgca
     3061 attgctggcg cgtttcctga accagttggt ccgttttctt tctgagacta ctgtagagag
     3121 gattgaccaa tcgagataac cctacaatga caatggtcaa aatggcaacc atgactaaga
     3181 accagaaagt caactcagct gagattcgat aagccataaa aatggcacca aaaacgataa
     3241 tgggcgctcg taaaaagaga cgcaggaatt gattgatacc agtctgaatc tggtaggtat
     3301 ccgaagtcaa gcgagtaacc aaactagaag ttgtcagacg gtctctgctg tcctttggca
     3361 aggaaagaat atgacgataa agatcgtttg tcaattcctt agcaaaacct actgctgcct
     3421 ttgctgagta aaattgagct atcaaggcca ctaaaacgcc aattactgca aagataagga
     3481 gcaggccaat ctgcatccag agatgacctt gatctccctg aggtaaagat tggtcaacaa
     3541 tcccagcaat caccatggga accaagagct caaaaacagc ttctaacagc ttgaacaagg
     3601 gggctaaaat tgattccttg atgtagggtt tgaagtaaga taataggtgt ttcataaatc
     3661 ccttctattc atattctaga aatgaagaaa gtgggaagcc ccactctctg ttttatttgt
     3721 ttaagtaagg caatagatag ccatatcctg ctttttccat ctcatccttg gccacaaagc
     3781 gtaaagaagc agaattgata cagtaacgga ggccgcctaa ctcccgcggt ccatctgtga
     3841 aaacatgacc caagtgagca ctgcctgaac gagaacgaac ttcaattcgc tccattccat
     3901 ggctcagatc cttgtaataa tgaatcaact ctttggaaat cggacggcta aaacttggcc
     3961 aaccacaacc tgaagcaaac ttatccttgg caaaaaagag tggctcacct gtcgtaatat
     4021 ctacataaat cccctcttca aaggtttggt cataggcatt ggtaaatgga gcctctgtag
     4081 cagcttcttg tgtgacacga taagactctt cagatagact ggccttcaac acctcttgac
     4141 taggcttttc atagtttgct gcatcaatca atggcttatc agcatcggtc acatcgatat
     4201 gacagtaacc tgaaggattc ttcctgagat agtcttggtg gtagtcttca gccagaatgt
     4261 agtggcgtaa ttgctccact tctactgcaa tctttcgacc cagcatgcgt tcctgctcct
     4321 gcaccactgt gtagatagct ggcaaatctg cttcatcctg ataataaatc ccagttcgat
     4381 attggcggcc acggtcattc ccttgttgat tgatagatag aggatcgata actcggaaat
     4441 aataaagtaa aatctctctg agtgacactt ccttctcatc gtaaatcact tggaccgttt
     4501 ctgcatggtc tgtttccttg atcaactggt aattggtcgt ttcgacttga ccattagcgt
     4561 agccaacact ggtttctagc actccagaaa tgcgtgaaaa atattcctct aggccccaaa
     4621 aacaaccacc tgctagataa atttctgcca tctttatttc tcctttatca cgtttttaac
     4681 taatactctt cgaaaatctc ttcaaaccac gttagcgtca ccttaccgta tatatgtt
//
LOCUS       DBERCW010000069         4572 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.069, whole genome shotgun sequence.
ACCESSION   DBERCW010000069 DBERCW010000000
VERSION     DBERCW010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4572
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.069"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(58..1068)
                     /locus_tag="ACL72M_002052"
     CDS             complement(58..1068)
                     /locus_tag="ACL72M_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGS0717103.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1217..2386
                     /locus_tag="ACL72M_002053"
     CDS             1217..2386
                     /locus_tag="ACL72M_002053"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0717104.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2383..3153
                     /gene="recO"
                     /locus_tag="ACL72M_002054"
     CDS             2383..3153
                     /gene="recO"
                     /locus_tag="ACL72M_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGS0717105.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3150..4142
                     /gene="plsX"
                     /locus_tag="ACL72M_002055"
     CDS             3150..4142
                     /gene="plsX"
                     /locus_tag="ACL72M_002055"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGS0717106.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4148..4381
                     /locus_tag="ACL72M_002056"
     CDS             4148..4381
                     /locus_tag="ACL72M_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS0717107.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4427..4572
                     /locus_tag="ACL72M_002057"
                     /pseudo
     CDS             4427..4572
                     /locus_tag="ACL72M_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         1340 a          878 c         1163 g         1191 t
ORIGIN      
        1 aacatatacc tacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtgtta
       61 gaaaatgccg ataagggtct gcataccaag agtggtgagg atgatggcaa tccagcagat
      121 ggctccaaga acaatggatt ttccactgga tttgaccata gcgaccagat tggttttgag
      181 accgatagca ctcatggcca tgacaataag gaatttagag agttgtttga gaggggtaaa
      241 gaaactactg gacacaccta gagaggtgag tagtgtagtg aggagagagg caaggataaa
      301 gtaaaggata aaaagtggga agactttttt cagttgtagg ctttgcttgt tttcttgttg
      361 gcgactttgc cagtaggata gaaagagcgt gatagggata atggccaaag tacgtgtgag
      421 tttaacaatg gttgcagact cgagggtatt gctttggtaa agactgtccc aagcgctggc
      481 ggcagccgtt acagaggaag tgtcgttgac cgcagtccct gcaaagaggg cgaagccttc
      541 attggataga tgaagccagg tgccgagggt tggaaagatg agcgcagcca agacattgaa
      601 gaaaaagata acggaaatgg cttgggctac ttccttttcc ttagcatgga taacaggcgc
      661 tgtcgctgca atggcagaac ccccacagat agaagaacct actccaacca aggtagccag
      721 ttttgtatcc agtgcaaaga aacgctggaa gaggtaggca ataatcagag ctattgagat
      781 agtggacagg atgacaggga gtgaagattg gccaactgcg aagacctgcg agatattgag
      841 accaaaacca agcaagacaa cggcatattg gagcaacttc ttggaactaa aggtcaaacc
      901 agcatccagt tgtttatagg acgagagaaa gggatgtagg agcatgccta tgaaaatggc
      961 aaaaacgggc gcgccaatca cagggaagaa tcctcctaag taccaagata ggatggaaat
     1021 gagaaggcag gccaagatac ctgctccatt ttttgataga aatgacataa aaacctccaa
     1081 ataaaatcta ttaccattat agacctataa acaggaaaag taaaatagaa agtggaaagc
     1141 tattctctaa tgtatttttg cggtcggggg gcttttgtag tataatagag atacgttttg
     1201 aaagtaggag gtatctatgg acttaactaa gcgctttaat aaacagttag ataaaattca
     1261 agtttcgttg attcgtcagt ttgaccaggt tatttcggag attcctgggg tcttgcgttt
     1321 gaccttgggg gaacctgatt ttacaacgcc agaccatgtc aaggaggcgg ccaagcgagc
     1381 gattgatcag aaccaatcct actatacagg gatgagtggt ctgctgactc tacgtcaggc
     1441 agccagtgac tttgttaagg aaaagtacca actggactat gctcctgaaa atgaaatctt
     1501 ggttacaatt ggggcgacag aggctttatc tgcgactttg acggctattt tggaagaggg
     1561 agacaaggta cttttgccag ctcctgctta tccaggctat gaaccgattg ttaacttagt
     1621 tggggcagaa attgttgaga ttgatacgac tgaaaatggt tttgtcttga ctcctgagat
     1681 gttggagaag gccattttgg agcagggtga taagctcaag gcggttattc tcaactatcc
     1741 agccaatccg acaggaatta cctacagtcg agagcagtta gaggccttgg cagctgtttt
     1801 acgcaagtac gaaatttttg ttgtctgtga tgaggtttac tcagaattga cctacacagg
     1861 cgaagcccat gtgtctctag gaacgatgtt gagagaccag gctattatta tcaatggttt
     1921 gtctaaatcg catgccatga caggttggcg tttggggctg attttcgctc ctgcgacctt
     1981 cacagcccag ttaatcaaga gtcaccagta cttggtcact gccgcaaata ccatggcgca
     2041 acatgctgca gtagaagcct tgacggctgg taaaaacgat gcggagccca tgaagaagga
     2101 atatatccaa cgtcgggact atatcatcga aaaaatgact gctcttggtt ttgagattat
     2161 caaaccagac ggtgccttct atatttttgc taaaattcca gcgggctaca atcaagactc
     2221 ctttgctttt ctgaaggatt ttgctcagaa gaaggccgtt gcctttatcc ctggtgcagc
     2281 ctttggacgt tacggggaag gctacgtccg cctatcttat gcagccagca tggagactat
     2341 caaagaagcc atgaaacgac ttgaggagta catgagagaa gcatgattca gtctatcacg
     2401 agtcaaggct tggtgcttta caatcgcaat tttcgtgagg atgacaagct cgtcaaaatt
     2461 tttacagagc aggttggcaa acgcatgttt tttgtcaaac acgctggtca gtctaagctg
     2521 gcgcctgtta ttcagccctt ggtgctggca cgatttctct tgcgaatcaa tgatgacgga
     2581 ctcagttaca tcgaagacta tcatgaggtc atgacttttc ccaagattaa tagtgacctc
     2641 tttgtcatgg cctatgcgac ctatgtggca gctcttgcag atgctagttt gcaggacaat
     2701 cagcaggatg ctcccttgtt tgcttttttg caaaagactt tggagttgat ggaagcaggc
     2761 ttggattatc aggttttgac caatattttt gaaattcaaa ttttgactcg atttggaatc
     2821 agcctcaatt ttaatgagtg tgtcttctgc catcgggttg gtcaggcttt tgacttttct
     2881 ttcaaatatg gagcctgcct ctgtccagag cattatcatg aggataagag acgttgtcat
     2941 ctcaatccca atatccccta tctgctcaat caatttcaag ctattgattt tgagactttg
     3001 gagaccattt cgctcaagcc tggaatcaag caagagctac gccaatttat ggatcaacta
     3061 tatgaagagt acgttgggat tcacctaaaa tcaaagaaat ttattgattc cctagcagac
     3121 tggggacaat tactaaaaga ggaaaagaaa tgaaaaaaat cgcagtagat gccatggggg
     3181 gcgattacgc acctcaggcc attgttgagg gtgtcaatca agccctatct gacttttcag
     3241 atatcgaggt tcaactttac ggagatgaag ctaaaatcaa gcaatatctg acagcgacag
     3301 agcgcgtcag cattatccat acggatgaga agattgattc ggatgatgaa cctacgagag
     3361 ctattaggaa taagaaaaat gccagtatgg tattggcagc caaggctgtc aaagatggtg
     3421 aagcagacgc tgtcctttcg gctgggaata caggtgcctt gttggcagca ggattcttca
     3481 tcgtgggtcg tatcaagaat atcgaccgtc ctggactcat gtctaccttg cctaccgttg
     3541 atggaaaagg ttttgacatg ctagaccttg gtgctaatgc agaaaataca gcccagcacc
     3601 tccatcaata tgcggttcta ggttccttct atgctaaaaa tgtccgtggc attgcgcaac
     3661 cacgcgttgg tttgctcaac aacggaacag agagtagcaa gggcgacccg cttcgtaagg
     3721 aaacttatga attactggcg gctgatgaaa gtttgaactt tatcggaaac gtggaagcgc
     3781 gtgatttgat gaatggcgtt gcagatgttg ttgtggcaga tggtttcacg ggaaacgctg
     3841 tgctcaaatc catcgaaggg acagctatgg gaatcatggg cttgctcaag acagctatta
     3901 caggtggtgg tcttcgagcg aaactaggtg ccctccttct caaggacagc ctcagtggtt
     3961 tgaaaaaaca gctcaattat tcagatgttg gtggagcggt cttgtttggt gttaaagcac
     4021 ctgttgtcaa gactcatggc tcaagcgatg ccaaggctgt ttatagtacg attcgtcaga
     4081 tccgtaccat gctagaaaca gacgtggttg cccagactgc gcgtgaattt tcaggagaat
     4141 aaaagagatg acagaaaaag aaatttttga ccgtattgtg accattatcc aagagcgaca
     4201 gggagaggac tttgtcgtga cagaatcctt gagtctgaaa gacgatttgg atgcggattc
     4261 tgttgacttg atggagttta tcttgactct ggaagatgaa tttagtatcg aaatcagcga
     4321 tgaagaaatt gaccaactcc aaaacgtagg agatgtggtt aaaatcattc aaggaaaata
     4381 gtaatcggag ttccaagtca acggaagtag atggttttta gaaatgagaa atatcggaca
     4441 agctggtaaa atcttggctg acagtggtta tcaagggctc atgaagatat atcttcaagc
     4501 acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gctgaagata aagcctataa
     4561 ccatgcgcta tc
//
LOCUS       DBERCW010000070         4190 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.070, whole genome shotgun sequence.
ACCESSION   DBERCW010000070 DBERCW010000000
VERSION     DBERCW010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.070"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            128..373
                     /locus_tag="ACL72M_002058"
     CDS             128..373
                     /locus_tag="ACL72M_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717108.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFTKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            774..1766
                     /locus_tag="ACL72M_002059"
     CDS             774..1766
                     /locus_tag="ACL72M_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0717109.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1768..2586
                     /locus_tag="ACL72M_002060"
     CDS             1768..2586
                     /locus_tag="ACL72M_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0717110.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2588..3373
                     /locus_tag="ACL72M_002061"
     CDS             2588..3373
                     /locus_tag="ACL72M_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0717111.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3471..3689
                     /locus_tag="ACL72M_002062"
     CDS             3471..3689
                     /locus_tag="ACL72M_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGS0717112.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3674..3835
                     /locus_tag="ACL72M_002063"
     CDS             3674..3835
                     /locus_tag="ACL72M_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HGS0717113.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
BASE COUNT         1169 a          714 c          899 g         1408 t
ORIGIN      
        1 tatagaaatt aattttactt tcccaatcga tttgttctca tcttatttca atccgctata
       61 tattatggta tcgaatcttc atcagaatga taaaattaat caattaatat ctgattacaa
      121 acagaatatg aaagcttttt atatcactat tgaaaaattt atacgagatg atgaaagcct
      181 taagtgttat tttacaaagg ttatttcaag tcgttccaag gtaacaagtc tagatcagat
      241 tgaagctgat aaaacgatac aaagaaaata ttcaagtgag ctaaaaaaat ttattggatt
      301 ttataatgag attatttgtg aggaaaatag tttcctacat gtacgaaaga ggtggtcgag
      361 ttggtttagg tagtcggtgc gtgagttgat aattctcagg gtatggactt ctttttcatg
      421 aatgaggtaa aagagcaggt attgtttaga gacaatcatt ctgagcatat tttctggata
      481 gagggagtat ccgattttat gatcaaagtt aataccgccc tctggtgaga agatgagtag
      541 gttggtaatt taaactatta aacagaattt ttgattaaaa gtattatttc atgagagaaa
      601 tcctaatttc acaatctata ggcaaacgct tgcatttcgt tttttattgg actataatag
      661 gttggtataa agccttctgt agtaataaaa tgtagaaggt gtagaaagta aggatttaga
      721 atatttgtag ttaaaaacac aatgttgcta ttccttacga tagggagata gatatggcaa
      781 tgatagaagt ggaacatctt cagaaacatt ttgtgaagat tgttaaggaa ccgggcttga
      841 agggggcttt gcgctccttt attcatcctg aaaagcagac ctttgaagcg gtcaaggatt
      901 tgacctttga ggttccaaaa gggcagattt taggatttat cggggcaaat ggtgctggga
      961 agtcgacaac cattaaaatg ctgacaggaa ttttgaaacc aacatctggt ttttgtcgga
     1021 ttaacggcaa gattccccag gacaatcggc aagattatgt caaagatatt ggcgtagtct
     1081 ttggacaacg cacccagcta tggtgggatt tggctctgca agagacctac actgtcttaa
     1141 aagagattta tgatgtgcca aactcgctct ttcataagcg tatggacttt ttgaatgaag
     1201 tcttggattt gaaggacttt atcaaggatc ccgtgcggac tctttcactg ggacaacgga
     1261 tgcgagcgga tattgcggcc tccttgctcc acaatcccaa ggttcttttt ttagatgagc
     1321 cgaccattgg tttggacgtt tcggttaagg ataatattcg tcgggcaatt actcagatca
     1381 atcaagagga agaaactacc attcttttga ccactcacga tttgagtgat attgagcaac
     1441 tttgtgatcg gattttcatg attgacaagg ggcaaaagat ttttgatgga acggtgagcc
     1501 aactcaagga gacctttggt aagatgaaga ctctctcttt tgaactgcta ccaggtcaaa
     1561 gtcatctcgt ctctcactat gaaggtctgt ctgatatgac cattgataga caaggaaaca
     1621 gcctcaacat tgaatttgat agttctcgct accagtcagc tgacattatc aagcaaaccc
     1681 tatctgattt tgaaatccgc gatttgaaga tggtggatac ggatattgag gatattatcc
     1741 gtcgcttcta ccgaaaggag ctctaggatg atcaaattgt ggagacgtta taaacccttt
     1801 atcaatgcag gggttcagga gttgattact taccgagtca actttattct ctatcggatt
     1861 ggcgatgtca tgggggcttt tgtggccttt tatctctgga aggctgtctt tgattcttcg
     1921 caagagtctt tgattcaggg cttcagtatg gcggatatca ccctctacat catcatgagt
     1981 tttgtgacca atcttctgac tagatccgat tcgtccttta tgattgggga ggaggtcaag
     2041 gatggctcca ttatcatgcg tttgttgcga ccagtgcatt ttgcggcctc ctatcttttc
     2101 accgagcttg gttccaagtg gttgattttt atcagcgttg gccttccatt tttaagtgtc
     2161 attgtcttga tgaaaatcat atcgggtcaa ggtattgtag aggtgctagg attaactgtc
     2221 ctttatcttt ttagcttaac gctcgcctat ctgattaact ttttctttaa tatttgcttt
     2281 ggattttcag cctttgtgtt taaaaatctt tggggttcca acctacttaa gacttccata
     2341 gtggctttta tgtcggggag tttgattccc ttggcattct ttccaaaggt tgtttcagat
     2401 attctctcct ttttgccttt ttcgtccttg atttatactc cagttatgat cattgttgga
     2461 aaatacgatg ccagtcagat tcttcaggca ctccttttgc agttcttctg gctcttagtg
     2521 atggtgggat tgtctcagtt aatttggaaa cgggtccagt cctttatcac cattcaagga
     2581 ggttagtatg aaaaaatatc aacgaatgca tctgattttt atcagacaat acatcaaaca
     2641 aatcatggaa tataaggtgg attttgtggt tggtgtcttg ggagtctttc tggctcaagg
     2701 cttgaatctc ttgtttctca atgtcatctt tcaacatatt ccattcctag aaggctggac
     2761 ctttcaagag atagctttca tttatggatt ttccttgatt cccaagggaa tggaccatct
     2821 cttttttgac aatctctggg cactagggca acgcctagtc cgaaaaggag agtttgacaa
     2881 gtatctgact cgtcccatca atcctctctt tcacatccta gttgaaacct ttcagattga
     2941 tgccttgggt gaactcttag tcggtggtat tttattggga acaacagtga ccagcatagt
     3001 ttggactctt ccaaaattcc tgcttttcct agtttgtatt ccttttgcga ccttgattta
     3061 tacttctctt aaaatcgcaa cagccagtat cgccttttgg actaagcagt caggcgccat
     3121 gatttacatc ttctatatgt tcaatgactt tgctaagtat ccgatttcta tttacaattc
     3181 tcttcttcgt tggttgatta gctttatcgt gcctttcgcc tttacagcct actatccagc
     3241 tagctatttc ttacaggaaa aggatgtgtt ctttaacgta ggaggtttga tgttgatttc
     3301 tctggttttc tttgttattt cccttaaact ttgggataag ggcttagatt cctacgaaag
     3361 tgcgggttcg taaaagctaa agtaagacta aaatcaagaa aggaacttat gatgtttgta
     3421 attgaagaag tcaaggatga aaatcaaaaa aggcagttgt cgttgaggtt ttgaaggatt
     3481 tgccagaatg gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac
     3541 tgcaagtttg gaccgcctat caggagagtg atttgactgg atttgtaagg ttatcctatt
     3601 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3661 aattgggagc caattgcttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct
     3721 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3781 tcgaggtctt ggctttaaaa agttagagat tttttctcag ctatggaatc cgtaaaatcc
     3841 ttgtcagatt ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgcc
     3901 atactgtaag tgtaatcgcc gatttagctc agttggtaga gcaaggcact cgtaaagcct
     3961 aggttatagg tagataaacg actgaggagt tgaaaaaata gataggtaga agataaccgt
     4021 taagccttat tcttagcggt tatttatatt gtttaatagc gctgatattt catcaattat
     4081 gcctgttttc gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga
     4141 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactcat
//
LOCUS       DBERCW010000071         4058 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.071, whole genome shotgun sequence.
ACCESSION   DBERCW010000071 DBERCW010000000
VERSION     DBERCW010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.071"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL72M_002064"
     CDS             371..598
                     /locus_tag="ACL72M_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717114.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3768
                     /gene="nanA"
                     /locus_tag="ACL72M_002065"
     CDS             886..3768
                     /gene="nanA"
                     /locus_tag="ACL72M_002065"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGS0717115.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKISRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYGNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQKIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1381 a          672 c          886 g         1119 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacgctt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataggctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaatttggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gggagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaatttc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacggtaa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgcca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaat
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gttattggct tggagtttga ctcagaagta
     3301 ttggtcaaca aggctccaac ccttcaattg gcaaatggta aaacagcgac tttcctaacc
     3361 cagtatgata gcaagacctt gttgtttgca gtagataagg aagatatcgg acagaaaatt
     3421 attggtatag ctaaaggaag catcgaaagt atgcataatc ttcctgtaaa tctagcaggt
     3481 gccagagttc ctggcggagt aaatggtagc aaagcagcgg tgcatgaagt tccagaattt
     3541 acagggggag ttaatggtac agagccagct gttcatgaaa tcgcagagta taagggatct
     3601 gattcgcttg taactcttac tacaaaagaa gattatactt acaaagctcc tcttgctcag
     3661 caggcacttc ctgaaacagg aaacaaggag agtgacctcc tagcttcact aggactaaca
     3721 gctttcttcc ttggtctgtt tacgctaggg aaaaagagag aacaataaga gaagaattct
     3781 aaacatttga ttttgtaaaa atagaaggag atagcaggtt ttcaagcctg ctatcttttt
     3841 ttgatgacat tcaggctgat acgaaatcat aagaggtctg aaactacttt cagagtagtc
     3901 tgttctataa aatatagtag attgaaataa gatgtgaaca actctatcag gaaagtcaaa
     3961 ttaatttata gaaaaatttt agtagtcaag gtgtactgtt atagattcaa tatattatgt
     4021 gactattaac cttgtcttct cctaaaattg actttctt
//
LOCUS       DBERCW010000072         3445 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.072, whole genome shotgun sequence.
ACCESSION   DBERCW010000072 DBERCW010000000
VERSION     DBERCW010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.072"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..270
                     /locus_tag="ACL72M_002066"
     CDS             <1..270
                     /locus_tag="ACL72M_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717116.1"
                     /translation="VTHYKYYRAENSHLIYADYFEMKLQKLLKDDTKVFEKSTFKFVE
                     GYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(628..1161)
                     /locus_tag="ACL72M_002067"
     CDS             complement(628..1161)
                     /locus_tag="ACL72M_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGS0717117.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1250..2026)
                     /gene="recX"
                     /locus_tag="ACL72M_002068"
     CDS             complement(1250..2026)
                     /gene="recX"
                     /locus_tag="ACL72M_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGS0717118.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2064..3419
                     /gene="rlmD"
                     /locus_tag="ACL72M_002069"
     CDS             2064..3419
                     /gene="rlmD"
                     /locus_tag="ACL72M_002069"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS0717119.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1133 a          580 c          603 g         1129 t
ORIGIN      
        1 gttacccact acaaatatta tagagccgaa aattcacatc taatatatgc agactacttt
       61 gaaatgaaat tacaaaaatt attaaaagat gacacaaaag tttttgaaaa atctacattc
      121 aaatttgtag aaggatataa aatatacctg acagaatcta aagaatctgg aattaaacaa
      181 atggacaatg tcataaaata ttttgagttt attgaatcta aaagtattgc tttatatttt
      241 caaaaacgat taaatgagct gatagattaa atatcatttt ctctgttaag atattgtttt
      301 taaaatattg tactaaatga ttgatgctat gtggaaatac aaaaaaatgt ttttgatacg
      361 aagttgacct gtatttttta tactaatcat tttcgtattt tttgtattaa acgatataag
      421 tttgttgtaa acttactagg aataaagaca ttaaaaaata atagtatatc tatttgtttt
      481 atatatttta cgaattctgc ataaatctct ttctagtaat gtgttgtaac tctgctataa
      541 tggatttatt cctttttgta tttacacaat ttattttata ctaccaaaaa aacaaggtca
      601 ggattttgtt cctgaccttt gacaacttta ccgattcttt agttctacat agcgcttgta
      661 ccaaatgttt acataggctt ctgagaaagg accacgtcca ttgttaatcc aatcaacaag
      721 aattttgaca tgttctttta aaatatagtc caagtcatca gaataattca ttttgcgttt
      781 gtgacgctcg tattcttcaa cgtccaagag acgtttttcc ccatctgtaa aaattttaac
      841 atccaaatcg taatcaatat acttcagtgc ttcttcatcc agatagtagg ggctagccat
      901 attgcaatag taagaagttc cattatcacg aatcatggca atgatattaa accaatattt
      961 cttgtgaaag taaacaatag ccggttctcg agtgacccaa cgacgaccat cactttcggt
     1021 aacaagtgta tgatcgttga caccaataat ggcgttttct gttgttttta gtaccatggt
     1081 gtcccgccaa gttcggtgga gactcccatc atgcttataa ctttgaattg taataaagtc
     1141 gccttctttt ggaagcttca taactaacca actttctaca atttataagt ttatcattta
     1201 ctattgtacc ataaaattac ctaaaatctg tgaatttcac ttggaaatat taaagatatt
     1261 ctctaagagc gcttgctata tccgaaaaat cgtagccctt tcgtgctaaa acttgagtta
     1321 aacgctgctt cagttcgtat ccttcatact ttcgagcata cttagtatat tgcttatcaa
     1381 gttccttgaa gatgagttct tgagtcgttt cttggtcaac ttggctatct aagtcgtcaa
     1441 aggcaatttt agcatcagaa taagagaagc ccttgttagt caagttctgg ataatcttat
     1501 cttgcagggc acgagctgga agttttccct catatttttt caatagttta ttggctacac
     1561 gttgagcaac ttcagaaaaa tcaaattctt tcaagttctc ttctatagta gattttgaaa
     1621 tccctttttg agatagtttc tgagtcagca cataaggacc cttgtctcct gaaagttgat
     1681 tggtattgat gatagcataa gcgtactgac catcattaat ccacttatct tctttaagat
     1741 tagcaataac ttgagaaacg atgtttttat caatatcgta ttttttcaga tattctctga
     1801 cttctttttc agtgcgtgct ttaaaggata agtggtagag agcgagattc ttaccataag
     1861 aaaattgagc aaagtcttga atctctttca attcctcttc gcttatcacc ttatctctcg
     1921 ataacataaa acgaacaatt gtatcttcgg tgatatagca tttgtcgcca ttatcaagct
     1981 ccatcaggta gagtcttttt ttcttttcaa gttttgtgat tttcatagct ctattataac
     2041 tcaaaatgtg ataagatagg ggtatgaatc tgaaagtgaa acaaaaaata ccattaaaaa
     2101 tcaagcgcat gggaattaac ggtgagggaa tcggctttta ccaaaaaaca ttagtctttg
     2161 taccaggagc tctcaaaggc gaagatatct attgtcagat tacttctatt agacgcaact
     2221 ttgttgaagc aaaattactg aaggtcaaca agaagtctaa atttcgaatt gtgccatctt
     2281 gtactattta taatgaatgc ggaggctgcc aaatcatgca cctgcattat gataagcagc
     2341 tggagttcaa gacggactta cttcatcaag cgctgaaaaa atttgctcct gcaggatatg
     2401 aaaattatga aattcgtcca actattggaa tgcaggaacc aaaatattac agagctaagt
     2461 tacaatttca gactcgaaaa tttaaaaatc aggtcaaggc gggcttatat gcacaaaact
     2521 ctcactattt agtagagttg aaagactgcc tggtacaaga taaggaaacc caagtgattg
     2581 ctaatcgctt agcagaatta cttacttatc accagattcc aatcacggat gagagaaaag
     2641 ttctaggtgt ccgtactatt atggtccgac gcgcgagaaa gaccggacag gttcagatta
     2701 ttattgttac aaaccgccag cttaatttaa ctcaattggt aaaagagttg gttaaagatt
     2761 tcccagaagt tgtgacagta gctgttaata caaatacagc taaaaccagt gagatatatg
     2821 gtgaaaagac agagattatc tgggggcaag agagtattca agaaggtgta ctcaattatg
     2881 aattttcact atcccctcga gctttttatc aactaaatcc tgagcaaaca gaagtcctct
     2941 atagcgaagc agtaaaagcg ctggatgttg ataaagaaga ccatttgatt gacgcttatt
     3001 gtggagttgg aacgattgga tttgcctttg caaagaaagt taaaacactc agaggtatgg
     3061 atattattcc agaagctatt gaagatgcca agcgaaatgc taaaagaatg ggatttgaca
     3121 atactcatta tgaagctgga acggcagaag agattattcc tcgttggtac aaggaaggct
     3181 accgagcaga tgctttgatt gttgacccac cacgtacagg tctggatgat aagttattag
     3241 atactattct tacttatgta ccagaaaaaa tggtttatat ttcttgtaat gtttcgacct
     3301 tggctcgtga tttggtacgc ttagtagaag tctatgatct tcattatatc cagtcggtcg
     3361 atatgttccc acatacagct cgaactgaag ctgttgtaaa attaataaaa aaagtttaaa
     3421 aaagtagttg acaaagtttg aaaag
//
LOCUS       DBERCW010000073         3096 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.073, whole genome shotgun sequence.
ACCESSION   DBERCW010000073 DBERCW010000000
VERSION     DBERCW010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.073"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..1242
                     /locus_tag="ACL72M_002070"
     CDS             join(<1..332,332..1242)
                     /locus_tag="ACL72M_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS0717120.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYPKKVKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="ACL72M_002071"
     CDS             complement(1477..2085)
                     /locus_tag="ACL72M_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGS0717121.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2263..3021
                     /locus_tag="ACL72M_002072"
     CDS             2263..3021
                     /locus_tag="ACL72M_002072"
                     /inference="COORDINATES: protein motif:HMM:NF013539.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGS0717122.1"
                     /translation="MADYILVRDSEIVYETSSEIVSKVKVGEGTLNRFCKKIGYSGFQ
                     ELKLKMTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIELAIKLIREAN
                     QILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDLIIAFSLSGS
                     TKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGGSLMAKASQL
                     FIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
BASE COUNT         1174 a          395 c          571 g          956 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccca acttagaaca agtgaagagt
      901 atgttagaac aagcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttgaaatcgg agatgtttta tggttatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttg
//
LOCUS       DBERCW010000074         3093 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.074, whole genome shotgun sequence.
ACCESSION   DBERCW010000074 DBERCW010000000
VERSION     DBERCW010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.074"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(94..1380)
                     /locus_tag="ACL72M_002073"
     CDS             complement(94..1380)
                     /locus_tag="ACL72M_002073"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGS0717123.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(1611..1847)
                     /gene="comW"
                     /locus_tag="ACL72M_002074"
     CDS             complement(1611..1847)
                     /gene="comW"
                     /locus_tag="ACL72M_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGS0717124.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            2113..2910
                     /locus_tag="ACL72M_002075"
                     /pseudo
     CDS             2113..2910
                     /locus_tag="ACL72M_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2945..>3093)
                     /locus_tag="ACL72M_002076"
     CDS             complement(2945..>3093)
                     /locus_tag="ACL72M_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0717125.1"
                     /translation="HKLLPLPPYSPEYNPIEKTWAYIKKNLKKVLPSCNTFYEALFSC
                     SCFN"
BASE COUNT         1069 a          669 c          449 g          906 t
ORIGIN      
        1 aaagtttagg atatttgtta caacaagtta ggaggtcttc ttgtaactgt ctatagtata
       61 cccgacctat cttaaacaaa tcttaaaaat ctcttaggac caaacacttt ctaaaatatt
      121 tgtttgttca cgaccaggac ctactgagaa agtagaaata cgaacgccaa ccaattcact
      181 cacacgacga acatagttac gcgcattctc aggaagatct tccaaattgc gaactccggt
      241 aatatcttct gaccaacctg gcaactcttc atagataggc ttgcaacgtt tcaattgctc
      301 aagactagct ggatagtagt caatacgttg accgtcaaga tcataggcca cacagatttt
      361 cacagtatcc aaaccgctca aaacatcaat agagttcaaa gaaaggttag taataccaga
      421 aacacgacgg ctatgacgca tcacaactga gtcaaaccaa cctacacgac gtggacgacc
      481 agttgttgta ccatactcat gacccacttc acggatacgt tctcccactt catcaaacaa
      541 ctcagttggg aaaggaccat ctcctacacg actcgtataa gctttacata cacctacaac
      601 cttgtcaatc ttgcttggac cgacaccaga accaattgtc acaccaccag ctacagggtt
      661 tgatgacgta acaaatggat aagtaccttg gtcgatatct agcataacac cttgtgcacc
      721 ttcaaaaagc acacgtttgc cattatcaag cgcatcattc aagataacag atgtatctat
      781 cacgtatttc ttgatttgtt gaccatattc gtaatattct tcaaaaatat catcgaaaac
      841 aatcgcttta ctgtcataca atttttcaaa aagacgattc ttttcagcaa ggttacgttc
      901 taaacgctca cggaaaatat ctttatctaa aagatctgca atacgaattc caacacgagc
      961 agccttgtcc atataagctg gaccaattcc cttaattgtc gtaccaatct tattgtcgcc
     1021 cttagcttct tcttgcaagc gatccaactc gatatgataa ggcaaaataa catgcgcacg
     1081 atcagaaata cgcaagttat cagttgttac accttcctca tgaagatagc tcaactcttt
     1141 tacaagagat ttaggattta caaccatacc attcccaatg acagatattt tttcagggaa
     1201 gaaaatccca gatggaatca agtgcaactt aaatttctta ccgtcaatca caatcgtgtg
     1261 accagcatta tcaccacctt ggtaacgtgc aatcacttct gcattcgctg aaaggaagtc
     1321 tgtaatcttc cctttacctt catcacccca ttgggtacct acaacaacaa ctgaagtcat
     1381 aattttgtct gagccctcag gctcttcctt tctcacatac atggcaggac tctcacctgc
     1441 aattatatct tacaatttat tataataaaa aatcgccttt ttatcaagaa gaaacaatag
     1501 aaagatttgc tatttccaac tattaaaaaa tgatttagaa aaattactag ctatttacta
     1561 ttatctttac ataaaagagt aaattagttc ggaaatttac taaaattacc tcaacaagaa
     1621 ataaaacccc gattcattac caatttttca agatacaaac gataagcaac acgataatgg
     1681 taaacgataa aatccctatg acaaccaatg ccatatctca ctaaataata aattaaaaat
     1741 ttaaaatgaa catgttccca gtcaaaatta tcaccaaatg taggaccata ctcttcttca
     1801 atactatcat agaaattagc catctgctca taaatttttt gtaacataat caaatactcc
     1861 ttttcttttt tataaactta ttctaacaaa aaattttaca cattcactat caattcctga
     1921 attgttaaaa taccagcctc aacaagataa aaataggaaa agttgacaaa atagaaacaa
     1981 atttgctacc taaatttcaa acaattaaag ttctaaaaag accgccttaa aacttttggg
     2041 taaatcctat tagaactata atatttttat ataggtatta tggttctgat tttctagtat
     2101 aaaaaaattc aaactagaat tcttcttaga aaaggccgtt ttaagtgcta tcattgctca
     2161 aaaatggagc tcgctgagac ttctatcgtc aagaagaatc atcaaattcc ttgtatcatc
     2221 aaccaaaaga ttgctcaaaa gttaattgaa aagatttcta tgaccgacat tgatcatcag
     2281 ttgtctattt caacttcaac tgtcattcgc aagatcaata attttcactt tgagcatgat
     2341 ttttcgcgtc ttcctgagat tatgtcctag gacgttgaaa cagtccgggg agtgactgtt
     2401 tcaatcggga gatggagatg agctttattg ctcaggactt tgataaactc aatatcataa
     2461 ctgttcttga gagcagaaca caagccatca tccgaaatcc catgaataca aggctatcaa
     2521 gcgctactgg aagctcattc aacaagatag tcagaaactg agtgataaac gattttatcg
     2581 ccctactttt cgtatgcact tgactaataa agaaattcta gataaacttt tgagctattc
     2641 cgaagacttg aaacaccact ataatctcta tcagctcttg cttttccacc tctgtttcag
     2701 actttgttta aaaccttcct caaagataaa gagaaaatcg tcaacgccct tcaattacct
     2761 tattccaacg ccaaactgga agccaccaat aatctcatca aacttatcaa gcacaatgcc
     2821 tttggtttta ggaactttga aaacttcaaa aaagaaagga cgaaatttgt cctttctaga
     2881 tcttcgcttt cttcaaccca ctacagttga caaagaaccg aaaaatgtct cgcctctaat
     2941 atagtcaatt gaaacaagaa caagagaaaa gagcctcgta aaaggtattg caacttggta
     3001 ataccttttt gaggttcttt ttgatataag cccatgtttt ctcaatagga ttgtactcag
     3061 gtgagtaggg aggaagaggt aaaagtttat gcc
//
LOCUS       DBERCW010000075         2456 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.075, whole genome shotgun sequence.
ACCESSION   DBERCW010000075 DBERCW010000000
VERSION     DBERCW010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2456
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.075"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            199..>2456
                     /locus_tag="ACL72M_002077"
     CDS             199..>2456
                     /locus_tag="ACL72M_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HGS0717126.1"
                     /translation="MTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNA
                     TKDKANKSELTQTAEELSSKIASVHLGRRNLLKGTKELARYKPVSEYNGFKVIRTVAG
                     ATRYQDSYVERTVIPTAGTEYIAIFYARASENDYPVRCHFYNPNTVVSSENSSGYKSR
                     SSDGLSIIRLSTDWQLCWVKWTQTATDQAKTVIIGRHGPQVGGKEGVWVEICAPAIFE
                     GNLAGDWSPAYEDQDERVSAVESNFKQRADSLEAGVSRLTEGLRTKADISSLNVTAEN
                     IRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKASKSELTQTAEELAS
                     KIASVQVGGRNYIRGTKRMMLARGLWASGTFRPSGTGTAKTIDVSDSPATGFDKAIRL
                     TSSNARDQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLK
                     DENWTKLSFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATSSKEAPEDI
                     EGQISTVESTFKQRANSLEAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQN
                     KLNQKLSQAEFEVRAGSIHQEILNATKDKASKSELTQTAEELASRIASVQASGRNLFL
                     NSLFKQDISKTGIWTTSTYTAAIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALG
                     QFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIP
                     KGWTNESKQTTN"
BASE COUNT          779 a          499 c          616 g          562 t
ORIGIN      
        1 gaaggaaccg tttggatttg gatgccgaag tttgaaataa gcgatgtaga tacttcttat
       61 tcagaagctc ctgaagatat agaaggtcag atttcaacag ttgaatcgac cttcaaacaa
      121 cgagccaact cgctcgaagc tggtgtgaat cgtctgactg aaggccttag aactaaagcc
      181 gatatcagtt cactcaatgt gactgctgaa aatatccggc aatctgtgaa gagccttgag
      241 acagacacgc agaacaagct aaatcagaag ttgagtcagg ctgaatttga ggtgcgagct
      301 ggctctatcc gtcaagaaat cctgaacgca accaaggata aagccaacaa gtcagaactc
      361 acgcagacag ctgaggagct ctctagtaag atagcgagtg tgcacttagg gcgcagaaat
      421 ctgctgaaag gcacaaaaga gcttgcgaga tacaagccgg ttagtgaata taatggtttt
      481 aaagttatca gaacagtcgc aggagcaact agatatcagg atagctatgt ggaaagaacc
      541 gttataccaa cggctgggac agagtatata gctatctttt atgcacgagc cagtgaaaat
      601 gactatcctg tgcgctgtca tttttacaat cctaacacgg ttgtatcatc agaaaacagc
      661 agcggatata agtcaaggtc gtcagatggc ttgtctatta tccgtctctc gacagactgg
      721 cagttgtgct gggttaaatg gacccaaacc gcaacagatc aagccaagac ggtcatcatt
      781 ggccgccatg gccctcaagt aggcggtaaa gagggggtat gggttgaaat ctgcgcccct
      841 gccatttttg agggaaatct tgcaggtgac tggtcaccag catacgaaga ccaagacgaa
      901 cgtgtctcag cggtcgaatc caactttaaa cagcgtgctg attcactcga agctggtgta
      961 agccgtctga ctgaaggcct tagaaccaaa gccgatatca gctcactcaa cgtaactgct
     1021 gagaatatcc ggcaatctgt gaagagtctt gagacagaca cgcagaacaa actaaatcag
     1081 aagttgagtc aggctgaatt tgaggtgcga gctggctcta tccgtcagga aatcctgaac
     1141 gcaaccaagg ataaagccag caagtcagaa ctcacgcaga cagctgagga gctggctagt
     1201 aagatagcga gtgtgcaggt cgggggtagg aattatatcc ggggtacaaa gcgcatgatg
     1261 ctagccagag gattgtgggc atcaggtact tttagaccgt caggcactgg gacggcaaag
     1321 acgattgatg tatcagacag tccagcaact ggctttgata aagcgatacg attgacctca
     1381 agcaatgcta gagaccaaat aggtattgct caagatggat tttatatctc gcaaggcaca
     1441 tacacgatgt cttgttgggt caaaggcaga agaggtcaaa aggtcaagct acaaacttat
     1501 tggcaagtca atgataattc gggtatttcg cccatcttta cattaaagga tgaaaattgg
     1561 acaaagctat cgtttactag cgctagaaat agggctggag tcgcatcaat tggctatgtg
     1621 tatctcgtaa atgctgaggt cggagaatat ttagatgttc ttgcgcccca gctggaagac
     1681 ggaagtttgg caacaagctc aaaagaagct cctgaagata tagaaggtca gatttcaaca
     1741 gttgaatcga ccttcaaaca gcgtgccaac tcgctcgaag ctggtgtaag ccgtctgact
     1801 gaagggctta gaactaaagc ggatatcagc tcactcaatg tgactgctga gaatatccgg
     1861 caatctgtga agagtcttga gacagacacg cagaacaagc taaatcagaa gttgagtcag
     1921 gctgaatttg aggtgcgagc tggctctatc catcaggaaa tcctgaacgc aaccaaggat
     1981 aaagccagca agtcagaact cacgcagaca gctgaggagc tggctagtcg gattgcgagt
     2041 gtgcaggcat ccggtcgaaa tctattcttg aactcactat tcaagcagga tatttcaaaa
     2101 acaggaattt ggacaacgag tacatatacg gctgctatcg atagcgaaag taagtatctt
     2161 ggacataagg ctcttaaaat tataggtctg aatccatctg gccgtgatgg agggaatccc
     2221 aaggttactt acccagctct gggtcaattc gggaaagtaa ttcccggaag tacgactaat
     2281 caagatgtaa ccattagttt ttatgctaag gcaaataaaa atggaataat gctaagatct
     2341 cgattaggga atatcggata taaaactgga aatgtgacat tgtcgacaga aattaaacga
     2401 tatgttgtcc atattccaaa aggttggaca aacgaatcca agcagaccac aaatga
//
LOCUS       DBERCW010000076         2342 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.076, whole genome shotgun sequence.
ACCESSION   DBERCW010000076 DBERCW010000000
VERSION     DBERCW010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2342
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.076"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..186
                     /locus_tag="ACL72M_002078"
     CDS             <1..186
                     /locus_tag="ACL72M_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0717127.1"
                     /translation="RYPNPQKRIEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQIEI
                     RNSLDKTIDFSYSLSFS"
     gene            complement(152..1627)
                     /locus_tag="ACL72M_002079"
     CDS             complement(152..1627)
                     /locus_tag="ACL72M_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGS0717128.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT          697 a          517 c          429 g          699 t
ORIGIN      
        1 cgctacccta atcctcagaa aaggattgag gcaggatttg ataagctgat agaaattaag
       61 cgattgaccg cttctaattc aagggctttt tgccgtgctc taaaatcatc gccaaatcat
      121 caaattgaaa taagaaatag tttagataaa actattgact tttcttatag tttgtctttc
      181 tcttaataac gttgatatga ttgacctctg gatcttccgt cccttggagg gagcaaccac
      241 gttccttggc gaattggata tagtctacaa tttctcgtgt aatgcgttca ccaggagcca
      301 agataggaat ccctggagga tagcacatga caaattctcc acagacctgt ccaacagact
      361 catctaaggt caaacttttt ctctctgaat agaaggcttc ttgtggagac agcaccaact
      421 cgggctgaat atattctcct gctatcaaat cttttccatc tcttgaatag agtctcttaa
      481 tatcagccag agcaccaacc aagcgctcga tgtcttggat gcggtcgccg atggaaatat
      541 aggccaagat attgccgata tcaccaaact cgatctgaat gtcgtattcg tctcgcaaga
      601 ggtcataaac ctcgatacct gttaagccaa taccctgagt gtaaactgac agcttagtta
      661 cgtcaaaatc gcaaaccgaa acaccgtcta ttaactcttt tgagtaggca tagtagccac
      721 cgatagcatt gatttcacgg cgggcatact cagatagctc aatgactttc tcaaacgact
      781 ctttaccacg aagggccaag ttgcgacgtg aaatatccaa actagccatc aacaagtaag
      841 aggcagatgt agactgagtc aggttaatta tctgacgaac gtattcagaa ttcatctgct
      901 ccccgattaa aagaagcgaa ctttgtgtca aactcccacc agacttatgc atggaaactg
      961 ctgccatatc agctcctgca tccatagcag aaattggaag tttaccagtg aaatgcaaat
     1021 gcgctccatg ggcttcatct actaaaacca tcatgccagc ttcatgagcc atttctgtca
     1081 acccctttag gtctgaacag atgccgtagt aagtaggatt gttgattagg atagccttag
     1141 catctggatg gtcctttatg gcctgtgcta ctcggtcatt ttcaagacct aaagcgatac
     1201 caatcttagg atctacactc atctcgatat agatgggaat ggcaccacat agaaccaacg
     1261 cattgatagc agatttatgg acatttcgtg gcagaataat cttatctcct gccttgcagg
     1321 ttgccagaat catagtctgc accgatgaag ttgttccacc aatcattaga aaggcatggc
     1381 tagctccaaa agcatctgca gccagctcct ctgcatcacg aataatcgaa ataggatggc
     1441 ctaaattatc caagggtttc atcgaattga catcaatgcc tacacatttt tctcctaaga
     1501 gttcgacaag ttctggattt ccccgtccac gcttgtgacc tggaacatca aagggaacaa
     1561 tccttttctt gcgtaacttc accaaggcct cataaattgg ggcttggttt tgatctaact
     1621 ctttcaaaac atactccttt caatattttt aggaccttat gaaaactaag gaactaaagg
     1681 ttgactcatg aaaaaagagc aggttttcac ctgctctgca atcttctgac gtgtttattt
     1741 tggtttctgt tgagtatgtc tgttcccgat gtttcctaac tctctagtag caaatattac
     1801 gtactttatt gatcgtttca caagatgacg tgtgctttca ccacactaaa aatttatgaa
     1861 ttaggacaag tgtcctaaca tcaacttata aaagtaggct tttaacccta tcaataatgt
     1921 ggcttttcaa ccacgcttcg gcattcaacc ctgcctgtcc gtaggcattt tttactcggg
     1981 tttatatttg ctagaaaaca tcatctcatt ttctaagctt tattactata tcatgttttt
     2041 aagaacttgt aaagtatttt ttgataaaaa acaaaaatat agtagattga aactagaata
     2101 gtacacctct gcttctaaaa cattgttaga aatagatttt actgtcctga tcgatttgtt
     2161 ctgttcttgt ttcattttac tatatgttcg taaatgaaag ttctataatg aagttagcca
     2221 cccagccctc ctaaaaatta gatggttcaa ctagctgata gctcttgtag gcataagaaa
     2281 acacctctgt gttatacttg ttgttcaacc acaaacacaa gaaaggcaca gagatgcaag
     2341 ac
//
LOCUS       DBERCW010000077         2236 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.077, whole genome shotgun sequence.
ACCESSION   DBERCW010000077 DBERCW010000000
VERSION     DBERCW010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.077"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..1340
                     /locus_tag="ACL72M_002080"
     CDS             <1..1340
                     /locus_tag="ACL72M_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0717129.1"
                     /translation="IDVPYDIPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINW
                     IKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHD
                     GWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLS
                     EQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLN
                     DITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDG
                     DLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIV
                     QSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            1397..2194
                     /gene="psrA"
                     /locus_tag="ACL72M_002081"
     CDS             1397..2194
                     /gene="psrA"
                     /locus_tag="ACL72M_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGS0717130.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          803 a          315 c          400 g          718 t
ORIGIN      
        1 aaattgatgt tccttatgat attcctgata cttgggagtg ggtgaggttt tctacattgg
       61 ttgaaattgt cagaggtggc tctccacgac caatcaaaga ttatcttact tctgaagtag
      121 atggaataaa ttggataaaa ataggtgata ctgaaaaggg tgaaaagtat ataaataatg
      181 ttaaagaaaa aatcaaaaaa tcagggctta acaaaactag atttgtaaaa aaaggtacat
      241 ttttgttaac taattctatg agttttggta gaccttatat tttgaatgtt gatggtgcaa
      301 tacacgatgg atggttggct atttcgaact atgaaaactc attaaataaa gattacctat
      361 tctatattct ttcatcaaat gtagtttatt ctcaatttct atctctaatt agtggagctg
      421 ttgtgaaaaa cttgaatagt gataaagttg cttctattct tatccctctc cccccactat
      481 ccgaacaaca acgcataata gaagcaatcg aatcagcttt agaaaaagta gatgaatatg
      541 ctgaaagtta taatagacta gaacagctag ataaagaatt tccagataaa ctaaaaaaat
      601 ctattcttca atatgctatg caaggaaaat tagttgaaca agacccaaat gatgaatcag
      661 tcgaagtttt acttgaaaaa atacgagcag aaaaacaaaa actctttgaa gaaggcaaga
      721 ttaaaaagaa agatttggac atttctattg tttcccaagg agatgataac tcttattatg
      781 aggaagtacc ttgtgaaata ccagaaagtt gggaatgggt gaggttaaac gatataacct
      841 cctacattca aagagggaag tctccaaaat attcaaatat tcctatatac cctgtgattg
      901 ctcagaaatg taatcaatgg tctggctttt ctattgactt agcaagattt attgatcccg
      961 aaacagttca tagttaccag aaagaaagat tactaagaga tggtgattta atgtggaatt
     1021 caacaggtct aggtacgtta ggacgattag ctatttacca tgaaaataaa aatccttatg
     1081 gctgggctgt tgcagatagc catgttacag ttataagagt cttatcggga gttattaatt
     1141 gccatttcat ctataatttt ctttcctctc ctattgttca gtcagttatt gaagaaaaag
     1201 cgtcgggtag tacaaaacaa aaagaattat taacgaaaac tataaaagaa tatttaatcc
     1261 ccctcccacc ccttcctgaa caatccagaa tcgttgataa aatcgaacaa tttttcgccc
     1321 atattgacgc actaatttag tataatagtt ttacgtgcgg tggaatttct atcaaacata
     1381 agataggagt tttacgttga aagattttga attacatttg aagaaagctg gtttagctga
     1441 aaatactgtg cgttcgtacc tttatggtgt tcgatttttc ttggagaatt acgaactcaa
     1501 aatggaagat ttatttgaat acaaaggata tttattagac aattttaaac ctaaaactgt
     1561 caatttgcga ctacaaggag taaataaata tctggctttt attggtcatg atgatttgaa
     1621 attaaaattt gtcaaagtac agcaaaaacc atttttagaa gatgtcatta gccatgctga
     1681 ttaccttttt cttaaacgta gtttgaaaaa agatggtatt ttaaaatggc attttgtcgt
     1741 ttggttttta ggtgcaactg gggctcgtgt aagtgaactt attaaactaa aagtagagca
     1801 tgtagaaatc ggttattttg acatttactc aaaaggtggt aaaattcgta gactgtacat
     1861 tcctaaaaaa ttaagaaata gttgtcttag ttggttagaa tcagaaaatc gccgaagtgg
     1921 ttatttattt ttgaataaat ttaacgaacc aattacagca agaggagttg ctcaacagtt
     1981 aaaaaattat gctgataaat acaaaatgaa tcctaaagta atttaccctc attcttttag
     2041 gcatttattt gctaagaatt ttttagcgaa gtataatgat attgccttgc ttgcagattt
     2101 gatgggacac gaaagtatag aaactactcg aatttatcta aggaaaacag ctactgaaca
     2161 acaaaatatt gtagataaaa ttgttaattg gtaaaaaata acaggtggtc aaactgacta
     2221 cctgctattt ttgtga
//
LOCUS       DBERCW010000078         2149 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.078, whole genome shotgun sequence.
ACCESSION   DBERCW010000078 DBERCW010000000
VERSION     DBERCW010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.078"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..246)
                     /locus_tag="ACL72M_002082"
     CDS             complement(<1..246)
                     /locus_tag="ACL72M_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS0717131.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDTRFKRLVGVQRTTFKEML
                     AVLKTDYQLKHAKGGRKPKLSLEDLLMATLQYVREYRT"
     gene            complement(191..373)
                     /locus_tag="ACL72M_002083"
     CDS             complement(191..373)
                     /locus_tag="ACL72M_002083"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0717132.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            708..>2149
                     /gene="pcpA"
                     /locus_tag="ACL72M_002084"
     CDS             708..>2149
                     /gene="pcpA"
                     /locus_tag="ACL72M_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGS0717133.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGS"
BASE COUNT          771 a          302 c          349 g          727 t
ORIGIN      
        1 agtgcggtat tctcgcacat attgaagagt ggccataaga aggtcttcta ggcttaattt
       61 aggttttcgt ccaccttttg cgtgtttaag ttgataatct gtttttaaca cagctaacat
      121 ctctttaaaa gtggtacgct gaacaccaac aagacgctta aatcgtgtat cagttaattg
      181 tttacttgct tcataatttc gcagggagtc tattgactct ttggtaggtg tcaatgtttt
      241 tttcatctat accgagaatt attttcccgc catttgtatt tgcaaatgct gagtaggttt
      301 cccagaaaga ctctggaaga ttgtttttag cttttttgta ttctaaatca accccttcaa
      361 attttaagtc catatttttc ctttacatct gttttttgtg gttctggtat ttgttcaagt
      421 tgagtgataa tatagcgaat tgaatttcga gagtttttac tcagttaatt tcttttttaa
      481 cccgctttaa tttctttttt aacacgtgtt aaaaaagaaa ttaaagcggg ttaatttttc
      541 ttgacttaaa atttaaaaat gatatactgt gtttatggag agatgacaat ttataaaatg
      601 tactactcta ttctactaga taatgattga ataaaacttt ttataacaac ggctagcaaa
      661 gttataattt tatatctatt agaaaataaa tatgtaagga aatttaaatg aaaaaaacta
      721 caatattatc attaactaca gctgcagtta ttttagcagc atatgtccct aatgaaccaa
      781 tcctagcaga tactcctagt tcggaagtaa tcaaagagac taaagttgga agtattattc
      841 aacaaaataa tatcaaatat aaggttctaa ctgtagaagg taacataggc actgttcaag
      901 tgggtaatgg agttactcct gtagagtttg aagctggtca agatggaaaa ccattcacga
      961 ttcctacaaa aatcacagta ggtgataaag tatttaccgt tactgaagta gctagtcaag
     1021 cttttagtta ttatccagat gaaacaggta gaattgtcta ctatcctagc tctattacta
     1081 tcccatcaag cataaaaaaa atacaaaaaa aaggcttcca tggaagtaaa gctaaaacta
     1141 ttatttttga caaaggtagt cagctggaga aaattgaaga tagagctttt gatttttctg
     1201 aattagaaga gattgaattg cctgcatctc tagaatatat tggaacaagt gcattttctt
     1261 ttagtcaaaa attgaaaaag ctaacctttt cctcaagttc aaaattagaa ttaatatcac
     1321 atgaggcttt tgctaattta tcaaatttag agaaactaac attaccaaaa tcggttaaaa
     1381 cattaggaag taatctattt agactcacta ctagcttaaa acatgttgat gttgaagaag
     1441 gaaatgaatc gtttgcctca gttgatggtg ttttgttttc aaaagataaa acccaattaa
     1501 tttattatcc aagtcaaaaa aatgacgaaa gttataaaac gcctaaggag acaaaagaac
     1561 ttgcatcata ttcgtttaat aaaaattctt acttgaaaaa actcgaattg aatgaaggtt
     1621 tagaaaaaat tggtactttt gcatttgcag atgcgattaa acttgaagaa attagcttac
     1681 caaatagttt agaaactatt gaacgtttag ccttttacgg taatttagaa ttaaaagaac
     1741 ttatattacc agataatgtt aaaaattttg gtaaacacgt tatgaacggt ttaccaaaat
     1801 taaaaagttt aacaattggt aataatatca actcattgcc gtccttcttc ctaagtggcg
     1861 tcttagattc attaaaggaa attcatatta agaataaaag tacagagttt tctgtgaaaa
     1921 aagatacatt tgcaattcct gaaactgtta agttctatgt aacatcagaa catataaaag
     1981 atgttcttaa atcaaattta tctactagta atgatatcat tgttgaaaaa gtagataata
     2041 taaaacaaga aactgatgta gctaaaccta aaaagaattc taatcaggga gtagttggtt
     2101 gggttaaaga caaaggttta tggtattact taaacgaatc aggttcaat
//
LOCUS       DBERCW010000079         1861 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.079, whole genome shotgun sequence.
ACCESSION   DBERCW010000079 DBERCW010000000
VERSION     DBERCW010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1861
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.079"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(4..969)
                     /gene="xerA"
                     /locus_tag="ACL72M_002085"
     CDS             complement(4..969)
                     /gene="xerA"
                     /locus_tag="ACL72M_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGS0717134.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1087..1500)
                     /locus_tag="ACL72M_002086"
     CDS             complement(1087..1500)
                     /locus_tag="ACL72M_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGS0717135.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1497..1733)
                     /locus_tag="ACL72M_002087"
     CDS             complement(1497..1733)
                     /locus_tag="ACL72M_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGS0717136.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          364 c          276 g          680 t
ORIGIN      
        1 cttttaagag atgaattttt ggtgtgaatg cttgacatta ttttgattga ccatggcata
       61 ggccagggtt gtgtcaatct tgctatgacc tagcagtttt tggacttgtt cgataggcat
      121 acctttatca attgccttag tcgctaaagt tcttctgaac ttatgtgggt gaaccttttg
      181 tatgccgagt ttgtctccta actttcttaa gcgaatctct acaccagcaa ttccaagtct
      241 ctgggctttt ccaactagcg ttacaaaaag agcagggtga ctatcttttc tgtcgttaag
      301 ataatttctt aaatgaattt tcgtccgagc gtcaaaatat actggtctct ccttctttcc
      361 tttaccaaag acaacacact ctctgttttc aaaatcaata tctgaacgat tcaactgtac
      421 aagctcccct acacgcatac ctgtcgatgc tagtaggtct attattgcca aatctctcaa
      481 attttcacag ttatcacgca taatttccaa atgttcatca gtataagttt ccttcacatt
      541 ttgctcagtc ttaattttct ttatccgtcg aatgggattt ttaatgatat attcctcttg
      601 ctcaagccaa gcaaaaaaag aagacaatat acgcctaata ttgtctaaat ttgccttact
      661 acaatccttt tcagactggt aatttgctaa ataactcctt aaatcatctg ttgtgagttg
      721 tgtcacagac tctttaatag cattaaacaa gttttcaatc gtcctctggt aataacgaat
      781 tgtttttgag ctacagccct ctacctgctt ggcggtaata aatagttgca acaggttatt
      841 attcgaatac ttctgctgct tttttccgtc tactagatga tgttctaaac tctctctcaa
      901 cgctagtaat tgttcattat ttaaaagagg taacatttct tgcatgataa ttgtaacttt
      961 tgattccata atttctcact ttcttattca tcaataaaaa gagacaatat cagtttctgc
     1021 attacagaat tctaatattg tctgttcatt tattttcttg tgctcattca aatccagcat
     1081 actaggttac tttttgacct tttctctaac agaatgttca gaaacccatt tggagtagct
     1141 tgtcattttt tcatcagtta aagcttctac tgcgatggtt acacacattt ttactgcttc
     1201 ttctaccgtt acagaaaaac gatagccgtt taattgtaaa aatttgacca aaacgaagaa
     1261 agcagttctt ttattagcat tagcaaaaac atgcttcttt atcaattgga caaatagtat
     1321 cgttgcttta tcaaaaattg ttggataaag agacttccca aagacaaatt gttctggtaa
     1381 gttcacaatc atatttaagg cagaagaact aactgtttga attttctcat ttggagaata
     1441 ccgttgaatt gctaaagcat ttattttttc aatttgcttt tctgtcagat agattgtcat
     1501 ttttccacca aagctttgaa aacatcgtcg tattcgtcaa atattttatc taaatttaag
     1561 tcaaaggcat catcagatac ataagaaacc tgctgcccca attcttcagg agtaaagata
     1621 atctcaccac ttggtaacaa tttcgcttcg tatttaacac cacttggaat attaaattca
     1681 cttggaatcg taatggtgat tgaatttcct tgttttcttg tttttactac catctgattt
     1741 cctcctttga agtattataa caaatcatta ccgtaattac aatggcagaa tatcagccaa
     1801 aatactcctg catcagagat ttcttcaaag tttcaagttc ttccagagat ttttggattg
     1861 c
//
LOCUS       DBERCW010000080         1827 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.080, whole genome shotgun sequence.
ACCESSION   DBERCW010000080 DBERCW010000000
VERSION     DBERCW010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.080"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..959
                     /locus_tag="ACL72M_002088"
     CDS             <1..959
                     /locus_tag="ACL72M_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HGS0717137.1"
                     /translation="LFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVES
                     IRGSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVD
                     IKRYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDF
                     GFTHDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAES
                     RLIEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRD
                     KEGNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            971..>1827
                     /locus_tag="ACL72M_002089"
     CDS             971..>1827
                     /locus_tag="ACL72M_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGS0717138.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTEGSHLKKLKSYYL
                     GEHAILKHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLL"
BASE COUNT          576 a          328 c          434 g          489 t
ORIGIN      
        1 tcctattccg tggtttggat gatgaactca aaatcacatc tatcacggtc gatgtcggca
       61 gtctttgttg ggcatggttt gaggaagcat atcaaattga gactgaagac aagttcagta
      121 cagtagttga gtcaatccgt ggtagcctag atgtacctga tttctttaaa caaatcacag
      181 tcacatttaa cccgtggaat gagaggcatt ggctcaagcg tgtattcttc gatgaagaga
      241 cgagacgggc tgacacattc gctactacaa ccacttataa atgcaatgag tggcttgatg
      301 aagtcgatat caaacgctat gaggatttgt atcatacgaa ccccagacgt gctagaatcg
      361 tttgtgatgg tgaatgggga gttgctgaag gtttaatcta tgagaacgtg accgtcaagg
      421 atttcgataa ggatgaattg ctacgagatt cagctaataa gttatgtatc ggtcttgact
      481 ttggttttac tcatgatcca actgctttgt gttgttcgtt gataaatgac acgacgaaag
      541 agatttatgt ctttgatgag gcgtataaag tcggattgat aaccaaagaa gttgcgaaga
      601 tgataaaaga caaaggttat catcgctcac aaatcattgc tgatagcgca gagtcacggc
      661 tgattgaaga gctcaggtca gaacatggca tatctagaat aaaagagagt cggaaaggta
      721 aggatagtat tatggcaggc gtatccaaat tgcaaggata cgctatttat gtgcatccag
      781 attgtaaaaa catcatggat gaattttata gttactgcta ccagcgagat aaagaaggca
      841 actggttgaa taaaccagag gataaaaaca accacttgat ggacgctttg cgttacagcc
      901 ttcaatgtat cgaaggtgga aaagcaaccg tccgcagacg ttctgattat ggtctataga
      961 gaggaaagac atgtaccaat atttaaccta tccacgggat ggatatgatg agggttcttt
     1021 gaagaaagac ctgatttaca aattgataac gatacatagc actgaaggct cgcatttgaa
     1081 gaagcttaaa agctactatt tgggtgagca tgctatctta aaacacacga gacgcaacgt
     1141 gaacgcaccg aattacaaga cggtagccaa tcatgccaag gatatcgcag acacggctac
     1201 gggctatttt atgggcaatc ctatcaagta taacaatact gctgacggtg atatcgatga
     1261 actacttaca gcctttgatg gtgctgagat tgaccaagta gatgctcaga atgctttgaa
     1321 tatggctatc tatggtcgtg cttacgagta catctatgct aaagagggta tggctgagtt
     1381 ggattcaact agtattgatc cggagaatac tttcatggtc tacgatgata gtattgagcg
     1441 gaagcctttg tttgcggtct attactatga agtaaaagac gatacgaaag acactaccaa
     1501 gtaccaggct gaggtcttta ccgaaaatct gcactatcac atggtgctga gaagtacaga
     1561 ttcaggaaca actcagagcg aggaggcaac acctcacaac cttggtcaaa tcccaattat
     1621 cgaatatcgc aacaatcact ttgcaattgg tgactatgag caacaaatta gcttgataga
     1681 cgcttataat tccttgatgg ggaatcgtgt caatgataag gaacaggctg tagagtctat
     1741 ccttgtcttg tatggcacgc agttagcaga cactccagaa gacgctaagg tagcaatgaa
     1801 gattctttct gaagaaggtc ttttgga
//
LOCUS       DBERCW010000081         1662 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.081, whole genome shotgun sequence.
ACCESSION   DBERCW010000081 DBERCW010000000
VERSION     DBERCW010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.081"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            146..1492
                     /locus_tag="ACL72M_002090"
     CDS             146..1492
                     /locus_tag="ACL72M_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGS0717139.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          491 a          359 c          325 g          487 t
ORIGIN      
        1 tctaaaaacc atccagaatc cttgccttag cttagatcct ggatggtttc ttttttcacc
       61 caatgggtgt tttttactag acaaaaaaga gtttcccctt tatggtataa gtgtagaaaa
      121 aaacacaaaa agaaaggaaa ctcacatgaa cagtttacca aatcatcact tccaaaacaa
      181 gtctttttac caactatctt tcgatggagg tcatttaacc cagtatggtg gtcttatctt
      241 ttttcaggaa cttttttccc agctgaaact aaaagagcgg atttctaagt atttagtaac
      301 gaatgaccaa cgccgctact gtcgttattc ggattcagat atccttgtcc agttcctctt
      361 tcaactgtta acaggttatg gaacggacta tgcttgtaaa gaattgtcag ctgatgccta
      421 ctttccaaaa ttattggaag gagggcagct tgcttcacag ccaaccttat cccgttttct
      481 ttccagaact gacgaggaaa cagtccatag tttgcgatgc ctcaaccttg aattggtcga
      541 attcttttta cagtttcacc agctaaacca actcattgta gatatcgatt ctacccattt
      601 cacaacttat ggcaagcaag aaggtgttgc ttataacgcc cactatcgtg ctcatggcta
      661 tcatcctctt tatgctttcg aggggaagac aggttattgt ttcaatgccc agcttcgtcc
      721 tggtaatcgt tattgttctg aagaggcaga cagctttatc acacctgttt tagaacggtt
      781 taatcaactt ctctttcgaa tggatagtgg ctttgcgacc ccaaaattat acgatttaat
      841 tgaaaaaaca gggcaatact acctcataaa actcaagaaa aatactgttc tgagccgtct
      901 tggagacctt tccctccctt gcccacagga tgaggactta accatcttgc cccactccgc
      961 ctactcagaa actctctatc aagcaggatc ttggtcgcac aagcgtcgtg tctgccagtt
     1021 ctctgaacga aaagaaggaa acttgttcta cgatgttatt tctctcgtta caaatatgac
     1081 gagtggaaca agccaagacc agtttcagct ttatcgtgga cgtggtcaag ccgagaattt
     1141 catcaaggag atgaaggagg gattttttgg cgataaaacg gatagttcaa ccttaatcaa
     1201 aaacgaagtt cgtatgatga tgagctgtat cgcctacaat ctctatcttt ttctcaaaca
     1261 tctagctgga ggtgacttcc aaactttaac aatcaaacgc ttccgccatc tttttcttca
     1321 cgtggtagga aaatgtgttc gaacaggacg caagcagctc ctcaaattgt ctagtctcta
     1381 tgcctattcc gaattgtttt cagcacttta ttctaggatt agaaaagtca acctgaatct
     1441 tcctgttcct tatgaaccac ctagaagaaa agcgtcgtta atgatgcatt aaagaacagt
     1501 cgagatgaaa aaatcgtgtg acgaaccaag ggaggagtct gcccttttga ggaaatctag
     1561 cgaggaaaaa cgatactgga acagcagaaa gtaaaactga cctcatgagg aggaagaaag
     1621 tggctcatga ggtcaggggt tttgtaagtt acatctagtt ga
//
LOCUS       DBERCW010000082         1619 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.082, whole genome shotgun sequence.
ACCESSION   DBERCW010000082 DBERCW010000000
VERSION     DBERCW010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.082"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..689
                     /locus_tag="ACL72M_002091"
     CDS             <1..689
                     /locus_tag="ACL72M_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGS0717140.1"
                     /translation="TQKKLAELTGFKQNTISNHENGNRQLDEKDIRIYAQALEVSPQY
                     LFDLAKPSSIEIIPTTSPIQTIYDELEPPRQGKVLNYAKRQLKEQRNEEETKINEVSE
                     AIRLYSYDYYDHPASAGTGQYLNDVRVERIELPVDVDADFVIPIKGDSMEPDYHDGDL
                     VFIQTSVDLNDGVIGVFNYNGDAYIKQLVIDEDQAYLHSLNPEYKDMPITPDTDFRII
                     GEVVDLYREK"
     gene            691..891
                     /locus_tag="ACL72M_002092"
     CDS             691..891
                     /locus_tag="ACL72M_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717141.1"
                     /translation="MSNESRPMEVIKHNLDCKCHRRREWIRVNDKWHAIEFSVDDPNE
                     PPMTEEEKANVALILQQHLSKE"
     gene            1071..>1619
                     /locus_tag="ACL72M_002093"
     CDS             1071..>1619
                     /locus_tag="ACL72M_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGS0717142.1"
                     /translation="MITTNKVAIYVRVSTTNQVEEGYSIDEQKDKLSSYCDIKDWNVY
                     KVYTDGGFSGSNTDRPALESLIKDAKKRKFDTVLVYKLDRLSRSQKDTLHLIEDVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLSVFAQLEREQIKERMQLGKIGRAKAGKSMMWA
                     KTSYGYDYHRETGTITINPAQAL"
BASE COUNT          564 a          326 c          339 g          390 t
ORIGIN      
        1 taactcaaaa aaaacttgcc gagctgacag gttttaaaca aaatacaatt tctaaccatg
       61 aaaacggaaa tagacagtta gatgaaaaag atattagaat atacgctcag gctttagaag
      121 tttctcctca atatctattt gacctagcca aaccttcatc tattgaaatt atccctacca
      181 cttccccaat ccaaaccatc tacgacgaac tagaaccacc tagacagggc aaagtcctga
      241 attatgcaaa gaggcaactg aaagagcaga ggaacgaaga agaaacgaag ataaacgaag
      301 tatcagaagc tattcggctc tacagttacg actactacga ccacccagct tccgcaggta
      361 caggccagta tttgaatgat gtacgagtgg aacggattga gttaccagta gatgttgatg
      421 ctgactttgt catccccatc aaaggtgact ccatggagcc tgactaccac gatggtgacc
      481 tggtattcat tcagacaagt gtagatttga atgacggagt tatcggagta ttcaactaca
      541 acggcgatgc ttatatcaag cagcttgtta ttgatgaaga ccaggcttac ctacatagcc
      601 taaaccctga atataaagat atgccaatta caccagacac cgacttccga attatcggcg
      661 aagtcgtgga tttgtatagg gagaaataac atgagtaacg aaagtagacc gatggaagtg
      721 attaaacaca acctagattg caaatgccac agacgaagag agtggattag agtaaatgat
      781 aaatggcatg ctatcgagtt ttcggtagac gatccaaacg aacctcctat gacagaggaa
      841 gagaaagcca acgtggcctt aattcttcaa caacacttat cgaaagaata aaaccaactg
      901 tttccaaaat ggaaataatt gcaaacaaaa aaagccccac gctctcggtc ggcaaacttc
      961 tgagcgtgag gcatgtgaca ggaaaagatt ttcatggaga taacctctca tgatgtcttt
     1021 tcttgtaccc attttatcat tttttaggaa attttgaaag aggtactact atgataacaa
     1081 caaataaagt agctatatat gtcagggtat cgacgacaaa ccaggttgag gagggatact
     1141 ctatagatga gcaaaaagac aagctctcta gctactgcga cattaaagac tggaatgtat
     1201 acaaagtata tactgatgga ggtttctcag gatccaatac tgacagacca gcgctagaaa
     1261 gtcttatcaa agacgctaaa aaaagaaaat ttgacacagt tctagtctat aagctggacc
     1321 gtcttagccg tagtcaaaaa gacacgcttc acttgattga ggatgtattc atcaagaatg
     1381 ggattgaatt tctgagcttg caggagaact ttgacacctc tactcctttt ggtaaggcta
     1441 tgattggact cttgagcgtc tttgctcagc tagaaaggga gcaaatcaag gaacgcatgc
     1501 aacttgggaa aataggacgt gccaaggctg gaaaatccat gatgtgggct aaaacatcct
     1561 atggatacga ctaccacaga gagacaggaa ctatcactat caatccagct caggctctg
//
LOCUS       DBERCW010000083         1483 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.083, whole genome shotgun sequence.
ACCESSION   DBERCW010000083 DBERCW010000000
VERSION     DBERCW010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.083"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            154..402
                     /locus_tag="ACL72M_002094"
     CDS             154..402
                     /locus_tag="ACL72M_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6275 family protein"
                     /protein_id="HGS0717143.1"
                     /translation="MLKKAKQLASQEFSRLAGREIKEDCFVVWFSKTLQNWKALVSTN
                     AITSSEPCGDYAEITHNGDKNETYVDVYAKVSNRAIKD"
     gene            629..1153
                     /locus_tag="ACL72M_002095"
     CDS             629..1153
                     /locus_tag="ACL72M_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HGS0717144.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            1176..>1483
                     /locus_tag="ACL72M_002096"
     CDS             1176..>1483
                     /locus_tag="ACL72M_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HGS0717145.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     "
BASE COUNT          522 a          251 c          345 g          365 t
ORIGIN      
        1 ggtttgatgc acttgggaat atatggattg ctacacttga aggtgatatg gtagctaaaa
       61 aaggggatta tattatcaaa ggtgtgcaag gagaatatta tccatgcaag ccggatattt
      121 ttgcagaaac atacgaaaaa acggaggagt aaaatgttaa aaaaagcaaa acaattggca
      181 tcgcaagaat tttcacgctt ggcaggtcgt gaaatcaaag aagactgctt tgtagtttgg
      241 tttagtaaga ccctgcaaaa ctggaaagct cttgttagta cgaacgcaat tacatcaagc
      301 gaaccttgtg gagattatgc agaaattacg cataacggag ataagaatga gacttatgtg
      361 gatgtttacg ccaaggtttc aaatcgtgcc attaaagatt aggaggtgat ccaacatctt
      421 gacttgcagg aatagactgc tataaattac tgtaaattgc tataaaccgt gtcatatttg
      481 atgcggtttt cttatgctct aaccgtatgg aatcccgtac ggtttttata ttgtccaaac
      541 tgtgccgatg acattaaaag ctgtactgtt ccgtcgccgg acgtaaagcg agattatcga
      601 gtggcgacgt aatcgctgga ggacaattat gtcagaagaa atcaatgcaa ctgtatctac
      661 tgaatcaact gagactgtcg acactcaagg aaatgttgat tcagtgcagg aagaaaagca
      721 cgaacgaact ttcactcgtg ctgaaatcgg taagatgcta tctgccgagc gctctaaatg
      781 ggaagctgag caagaagcca aggaaaacga agctaagaag cttgctaaga tgaacgctga
      841 tgaaaaacag aaatatcagt tggatcagcg tgagcaagaa ctagctgacc gtgaaaaggc
      901 tattgctcgt aaggaattga ccgcagaggc taaagcaatg ctaagtgaac gtgacttacc
      961 tgttgagtta gtaaatgtag tcgatttgac aaacgcagag acggtatctg aatctatcac
     1021 ctctatccaa aaagcatggg aagagtcagt tcagaaggga gtctctgaac gtatgaaagg
     1081 tagtgcacct atcaaaaatg cacaaacagt ccagcaagaa gtcacggaaa aatggcgtaa
     1141 agacttcttg taataaaaga aaagaggaaa aataaatggc atttgaagaa ttaaacacag
     1201 cagaatcacg caagaaacat cttgggatta ttgaggatgt acttgcagta aattcatatt
     1261 caacaccact tgtgacatca agcgatgcag taaccttgca aggtcgctct tttacagtag
     1321 caactggtaa cacaacagag ttgaaagact acaaacgtaa caaagacaac gaatttgatc
     1381 acgttgaagt tgaagaaaag gtttataccc ttgatgaaga aaaatactgg ggtcgtttcg
     1441 tagatcaatt ggacgaacgt gactctaatg gtcaagtgaa tat
//
LOCUS       DBERCW010000084         1281 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.084, whole genome shotgun sequence.
ACCESSION   DBERCW010000084 DBERCW010000000
VERSION     DBERCW010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.084"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..>1281)
                     /locus_tag="ACL72M_002097"
     CDS             complement(<1..>1281)
                     /locus_tag="ACL72M_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HGS0717146.1"
                     /translation="VYQEAKTYLDKEVNKIFDKFQRDYGLSQVEARQVLKNMKDKKNL
                     NELRKVLEARPNDPNIQRLLADLDSPAYSFRMKRLERLSDDLDRMRESIYHSEKTGSD
                     AFYSDLMKDSYYKATFDLQQQTGLAYGFSGLPESEIKHLQSFSWVGDGSTYSTNIWKN
                     TGKLTSSIKDELLISLMTGRDTRETAQAIAERFNVGQNDARRLVRTESAFFHNQMELL
                     NYEEADIEKYIFVAVLDKRTSRICQEHDNQVYDRDKAVPGVNCPPMHPWCRSTTVGYD
                     EDADYSKLKRRARNPETGKVEYVPADMTYKEWYSKYVDGNRESIKRKAFDKTIKDGII
                     VSVSGTTIGHTPPGKIGLPNSVVQHNATNGDVLGRTYYDARGFKTKDVHFTNHKQPAR
                     HPYGKIGEHAHDFVFDDEGKFVSRSTRELTDDER"
BASE COUNT          327 a          310 c          225 g          419 t
ORIGIN      
        1 ttctttcatc atctgttaat tccctagtac tcctactaac gaacttacct tcatcatcaa
       61 atacaaaatc atgagcatgt tctccgattt ttccataagg atgacgtgcc ggttgtttat
      121 ggtttgtaaa atgaacatcc ttcgttttaa aacctctagc atcatagtaa gttctaccaa
      181 ggacatctcc gtttgtagca ttatgctgaa ctacactatt aggcaaacct attttgccag
      241 gcggagtgtg tccaattgta gtccctgata cacttactat tataccatct ttaatagttt
      301 tatcaaacgc tttacgttta atagactctc tattgccatc cacatacttg ctataccact
      361 ctttataagt catatcggca ggcacgtact caactttacc tgtctctgga ttccttgctc
      421 tgcgcttcaa cttgctgtag tctgcgtcct catcgtatcc gacagtagta gacctacacc
      481 aagggtgcat aggcggacaa ttgacaccag ggacagcctt atccctatca tagacctgat
      541 tgtcatgctc ctgacaaatg cgtgatgtac gcttgtctaa gacggccaca aagatatact
      601 tctctatatc cgcttcctca tagttgagta gctccatttg gttatgaaaa aaggctgatt
      661 ctgtccgaac caaacgcctt gcatcgttct gccccacatt gaaccgctca gcaattgctt
      721 gtgcagtttc tcgtgtatct cggcctgtca taaggcttat gagtaattca tcttttatgc
      781 ttgatgtaag cttccctgta ttcttccaga tgtttgttga gtacgtactt ccgtcaccta
      841 cccaactgaa agactgtaga tgtttaatct cgctctcagg aagcccagaa aagccgtatg
      901 ctagtcctgt ctgctgctgc aggtcaaagg tagccttgta gtaactatcc ttcatcaggt
      961 cgctataaaa ggcgtctgag cctgtctttt ctgaatgata gatagattca cgcatacggt
     1021 ctaaatcatc actcaaacgt tctagacgct tcatacggaa agaataagcc ggactatcta
     1081 agtcagccag tagtctttga atatttggat cattcggtct tgcttcaagc actttacgaa
     1141 gttcattcag atttttcttg tctttcatgt tcttcaagac ttgtctagct tctacctgac
     1201 ttagaccata atcacgttgg aacttatcaa aaatcttatt gacttcctta tccaagtaag
     1261 tcttggcttc ctgatagacc t
//
LOCUS       DBERCW010000085         1265 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.085, whole genome shotgun sequence.
ACCESSION   DBERCW010000085 DBERCW010000000
VERSION     DBERCW010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.085"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>1265
                     /locus_tag="ACL72M_002098"
     CDS             <1..>1265
                     /locus_tag="ACL72M_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717147.1"
                     /translation="RLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSML
                     PIINAIMPVLNSFAMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAG
                     GAGDLADAVDDAGDSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAG
                     GSGGGGKGGKGKGGGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFD
                     AAFRPEGIKRIKTALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSIATIGL
                     GIGVFLAESIANGLGRQKERIIRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTG
                     AVRIGSAIVSTLLSLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKTSSVFQSLLDTVAP
                     VFESIERSVNKFGDGLSRVYDEHVVPAINS"
BASE COUNT          354 a          233 c          326 g          352 t
ORIGIN      
        1 cgccttatgg ctattctgga acaggctaca gccaagtatg ggaatacctt gtctaattct
       61 gtaaatggtc gtatcagcct atttaagtcg ctgatgaagg acgcagcatt gaaccttggt
      121 aactctatgt taccgattat caatgccatt atgcctgtct tgaactcttt tgctatggtc
      181 ttaaagaacg ttactgctaa actcgctgag tttatcgctt tgatgttcaa caagaaagca
      241 acagtgaaag atggtgttgg tggagcagtt ggagacatgg gtaacgccat gaaggatgct
      301 gcaggcggag caggagacct tgctgacgca gtagacgacg ctggagattc agcaggagga
      361 cttgctgaca atcttggaga ctccgccaaa aacgctaaga aggccgctaa agagttgcta
      421 ggtcttttgg gatttgatga gattaacatc ttgcaaaaac caaaagatga cgacgcaggc
      481 ggttctggag gcggtggcaa aggtggtaaa ggaaagggag gcggtggcgg acctttcaaa
      541 gacatcttgc cagaagtcga gttgactgac atggacaaca aattcaagag catttttgat
      601 ggtcttggag ataagctcaa agggttgttt gacctcttca agaaaggttt tgatgcagca
      661 tttagaccag aaggtataaa acgcattaag actgccttag accaaatagc taagacaatg
      721 ggagaaatcg ccactgaccc aagggttgtg aatgccttta accgaatggc tgagaaaatt
      781 gcttatgctt tagggcaagt gacaggctca atagctacta tcgggctagg tatcggtgtt
      841 ttccttgccg aaagtattgc aaatggcctt ggaaggcaaa aagaacgcat tatcagggcg
      901 ctagtcgctt tgtttgataa tgttggtaac ctttccgagg cagtaggaaa catagctcag
      961 gacttttcta gtgctttcta cgacgtcatt acctcaactg gtgcggttcg tatcggtagc
     1021 gctattgtgt caactctgtt gagtttgaca tctaccattg ttgaagttgg tagtaaatta
     1081 gcaggaagtt tgtttaaagg ttttgaaaaa gtcgttgtga caagcgctcc taaaacttca
     1141 tcagtcttcc aaagtttatt agatactgtt gcgcctgtat ttgagagcat tgaaaggtct
     1201 gttaacaaat ttggcgatgg cttaagtcgt gtttatgatg aacatgtagt ccctgctatt
     1261 aactc
//
LOCUS       DBERCW010000086         1232 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.086, whole genome shotgun sequence.
ACCESSION   DBERCW010000086 DBERCW010000000
VERSION     DBERCW010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.086"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(103..516)
                     /locus_tag="ACL72M_002099"
     CDS             complement(103..516)
                     /locus_tag="ACL72M_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HGS0717148.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELEYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVNFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELTFVDGIGG"
     gene            complement(519..887)
                     /locus_tag="ACL72M_002100"
     CDS             complement(519..887)
                     /locus_tag="ACL72M_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717149.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWENFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            complement(884..>1232)
                     /locus_tag="ACL72M_002101"
     CDS             complement(884..>1232)
                     /locus_tag="ACL72M_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HGS0717150.1"
                     /translation="SIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQANHSGISP
                     EVSVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNI
                     SNYVRRKIREQIK"
BASE COUNT          337 a          279 c          209 g          407 t
ORIGIN      
        1 ccgatttttt cttccacagt tgcagcttga tgagatgtca aacgtagctt caactctttt
       61 tcgtcagtaa ctttccaagt tgtgtatttt aacgccattt aattaacctc caattccatc
      121 aacgaatgtc aattcagact gcaatgcaat cttaagtgtg aactcgataa cggcattgac
      181 accgccaccg ccaagtttta cagatacttg accttcaaaa ttgaccttag taccgtctgg
      241 gtaggtttgt tcaaagtaga gttttttctt gccatctgct gccttacgta atacacggta
      301 aggagctgtt gcgcttgaat tattataagc gaacttgtac tcaagttctc ctgcgtcccc
      361 gataccaaac tcgtacttct tcaccgtatc tgcaagagta gtattttcta ctttttcggg
      421 ctcgatacca aattcaggta cttccttaag ccctacaaga ttctgataat tgcctttcgt
      481 ttcactaaag gccaatttaa ttccatttgc taacatgttt aattctccat tctaaattga
      541 aaaacaagct ctgagtctaa atcaacgaca ccttcaaaac gcatgacctt atgtctcaaa
      601 tgagacgggt ctggcacgtc ttggcagtca gttcttcgca aacctaaaga ctcaaaaatc
      661 tgattgattt taacagctaa ctcactagtg ctggtatcat caaagatatc caccttatag
      721 cggatagatg atttttgttc ctggtcatca aaccaatcac ccggcttgtt ctgttcttct
      781 aaaaaaataa cgactgggaa attctcccaa tcgctaggat aagtatcggt cacattatct
      841 gcaacctttt gcaattcttt ataaataaca ggcttgatat taatcatttt atttgttctc
      901 ttatctttct acggacataa ttcgaaatat tcttagacac acgctcttga ttgtctctca
      961 aagctggata aagataaggc tgggcaggtt gaccatacat cttgtagaac tccccaatct
     1021 tttgaaagtg gtacggtcct acatttattt ggtcttcatg cacataccaa ggattagact
     1081 tgtaagtcac gctgacctct ggagagatac ccgaatggtt agcttgtcct attggtcctg
     1141 ttccaaactc aacgtaagga gcgtatttaa ggttggtgta aacttcgcct atagccttat
     1201 ctccgtccat ttttgctcta gttttgatac ta
//
LOCUS       DBERCW010000087         1162 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.087, whole genome shotgun sequence.
ACCESSION   DBERCW010000087 DBERCW010000000
VERSION     DBERCW010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.087"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..304
                     /locus_tag="ACL72M_002102"
     CDS             <1..304
                     /locus_tag="ACL72M_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717151.1"
                     /translation="ARPIFDEVPIVEEVKVEFGVEASMGRIYPETLIHLDISGYGNRV
                     HSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRFLTFRESDWKFFIRDLVNEFKH"
     gene            376..780
                     /locus_tag="ACL72M_002103"
     CDS             376..780
                     /locus_tag="ACL72M_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HGS0717152.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            861..943
                     /locus_tag="ACL72M_002104"
     tRNA            861..943
                     /locus_tag="ACL72M_002104"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:892..894,aa:Tyr,seq:gta)
BASE COUNT          379 a          192 c          265 g          326 t
ORIGIN      
        1 tgcacgacca atttttgacg aagttccaat tgtagaagaa gttaaggttg agttcggagt
       61 tgaagctagt atggggcgca tatatccaga aacgttaata catttagata tttctggata
      121 cggaaataga gtgcattcag tacatcgctt ccccggtatt ttactgagtg ttggtgagtc
      181 aatccaacta aagatgcttt tctataaaag acttagaaat tttactacag atcgtttctt
      241 gacgtttaga gaatctgatt ggaagttctt tatccgggac ctggtcaacg aatttaagca
      301 ttaaaaaagc caagacactc tctgcctcag ctaatagttc tcgcaaagac tattatatca
      361 caaaggagac agagagtgaa caaggctaaa gagctcttga aagagttgca ggatctggac
      421 atggacatcc aaagccgtat agacgaaatt aacgagcttg aggcaggttt gctctcaagc
      481 cctaaatggt ccgaggttaa agtccaaggt ggacagacta gaaaagttga tgatgtctat
      541 actcagttgg tagtgatgaa agaggctata gagcaggata ctaaagaggt cattaacaga
      601 aaacttgaat taggtagaat gatcaatagg cttaaaaatc caaagtacag ggcagtatta
      661 agaatgactt acatcaacaa aggcaccgct gatagcgttt gttatgattt gaatatgagt
      721 cgtacaacct actacaggtt aaaaaatgag gcggtcttag ctttggaaga agttatctaa
      781 cctcatagtg agcttatggg actttttgga acagcacggt tctaaaaatc tgttagaatg
      841 gtagtatcaa gaattgaaaa gagaggtctc agaattggta gatggttacc tgtaatgtca
      901 gggggctgta atggccttgg aggttcaagt cctcccctct cctttgagtg tttgtgtccc
      961 agaatgagtt aaatcttctg ggtggggatt cacatatcac tcattaactc ctatcactca
     1021 ttaacttaaa aatggttgcg gaagcgactg gacctcgcat gattgcgtag ctaattatat
     1081 tccggataag ttataagcta gagggtttga ttccctcaga ggttttaaag actacaaaaa
     1141 ataaaaaaga agtcaaaatt ta
//
LOCUS       DBERCW010000088         1148 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.088, whole genome shotgun sequence.
ACCESSION   DBERCW010000088 DBERCW010000000
VERSION     DBERCW010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1148
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.088"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            134..673
                     /locus_tag="ACL72M_002105"
     CDS             134..673
                     /locus_tag="ACL72M_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0717153.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            740..>1148
                     /locus_tag="ACL72M_002106"
     CDS             740..>1148
                     /locus_tag="ACL72M_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGS0717154.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLY
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
BASE COUNT          316 a          225 c          271 g          336 t
ORIGIN      
        1 tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat ctatacggca
       61 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taagaaaaaa tcagtcccct
      121 aaaggagcag attatgaagt tattgtctat cgccatttct agctataatg cagcagccta
      181 tcttcattac tgtgtggagt cgctagtgat tggtggtgag caagttggga ttttgattat
      241 caatgacggg tctcaggatc agactcagga aatcgctgag tgtttagcta gcaagtatcc
      301 taatatcgtt agagccatct atcaggaaaa taaaggccat ggcggtgcgg tcaatcgtgg
      361 cttggcagag gcttctgggc gctattttaa agtagttgac agtgatgact gggtggatcc
      421 tcgtgcctac ttgaaaattc ttgaaacctt gcaggaattt gagagcaagg gtcaagaggt
      481 ggatgtcttt gtgaccaatt ttgtctatga aaaggaaggt cagtcttgta agaagagtat
      541 gagttacgat tcagtcttgc ctgttcggca gatttttggc tgggaccagg tcggaaattt
      601 ctccaaaggc cagtatatca tgatgcactc gctgatttat cggacagatt tgttgcgtgc
      661 tagccagttc taattgcctg aacatacttt ttatgtcgat aatctctttg tctttacgcc
      721 ccttcagcag gtcaagacca tgtactatct gcctgtcgat ttctatcgtt atttgattgg
      781 gcgtgaggac cagtctgtca atgagcaagt gatgattaag tgcattgacc agcaactcaa
      841 ggtcaatcga ctcttggtag accaacttta tttgtcccaa gtgagtcatc ccaaaatgcg
      901 agaatatctg ctgaatcata ttgaaatcac gacggtgatt tccagtaccc tgctcaaccg
      961 atctggaaca gcggagcatc tggcaaaaaa acgccaattg tggacctata ttcagcagaa
     1021 aaatccagaa gtctttcagg ctattcgtaa gaccatgttg agccgtttga ccaaacattc
     1081 tgtcttgcca gatcgcaaac tgtccaatgt cgtctatcaa atcaccaaat ctgtttatgg
     1141 atttaatt
//
LOCUS       DBERCW010000089         1134 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.089, whole genome shotgun sequence.
ACCESSION   DBERCW010000089 DBERCW010000000
VERSION     DBERCW010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.089"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            119..>1134
                     /gene="pavB"
                     /locus_tag="ACL72M_002107"
     CDS             119..>1134
                     /gene="pavB"
                     /locus_tag="ACL72M_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGS0717155.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIP"
BASE COUNT          385 a          210 c          237 g          302 t
ORIGIN      
        1 taatataagt gttttataag agggatttaa gaaaaatttt aactttttct tagtcctttt
       61 taatttcagg agattatact agagtcatca aataaagaaa gactctaagg agaatcctat
      121 gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca gtgtcggtgt
      181 tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg
      241 tgccgatgtg gtcaatccga ccccaggtca agtcttacct gaagagacat cgggaacgaa
      301 agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga aacctgaggg
      361 cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag tgagcgagga
      421 aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc aagaaaatcc
      481 agagctaaca gatgccttaa aagaaactgt agatacagct gatgtggatg ggacacaagc
      541 aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga
      601 cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc ctttcactgc
      661 tggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt taactcgtct
      721 attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta aaaatcctgc
      781 tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag acttaaatgg
      841 caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta atggtactca
      901 aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg acttgactaa
      961 tctagttgct actaaaaatg tagacatcaa catcaatgga ttagttgcta aagaaactgt
     1021 cgaaaaagct gttaaagata acgttaaaga cagtatcgat gttccagcag cctacctaga
     1081 aaaagccaag ggtgaaggtc cattcacagc aggtgtcaac catgtgattc cata
//
LOCUS       DBERCW010000090         1106 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.090, whole genome shotgun sequence.
ACCESSION   DBERCW010000090 DBERCW010000000
VERSION     DBERCW010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.090"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..611
                     /locus_tag="ACL72M_002108"
     CDS             <1..611
                     /locus_tag="ACL72M_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HGS0717156.1"
                     /translation="SKLFIENEDFTSVQTGTVVNNGAIKPLQDYALTLDMAKQLAMMS
                     RTIKGAEIRQYFIQVEKDFNSPEKIMARALLMADQKVHKLEAQIEADRPKVLFADAVS
                     ASKSSCLIGELAKILKQNGIDIGQNKLFQWLRSNGYLISRRGESWNQPTQKSMQLGLF
                     ELKKTNINHADGHTTVSTTTKVTGKGQQCFINKFLNQEYLTG"
     gene            684..842
                     /locus_tag="ACL72M_002109"
     CDS             684..842
                     /locus_tag="ACL72M_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717157.1"
                     /translation="MKTVKKEWEPRIVNIMADGSQVDDLTGYVIPAGHSYYDIILGMH
                     KRELQKGA"
     gene            852..>1106
                     /locus_tag="ACL72M_002110"
     CDS             852..>1106
                     /locus_tag="ACL72M_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001163840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGS0717158.1"
                     /translation="MQYIIRNTNENYTQMNNHSAQNSELSLQAKGLLLVLMSNKDTWR
                     PYIDELSKRSRNGRDAHRAAFDELKEAGYIRIYRKSFGRGK"
BASE COUNT          372 a          212 c          247 g          275 t
ORIGIN      
        1 actctaaatt atttatagag aatgaagatt ttacaagtgt ccaaacgggt acggttgtaa
       61 ataacggagc tatcaaacct ctacaagatt atgctctaac tttggatatg gctaagcagt
      121 tggcgatgat gtctaggacg attaaaggag cagagatccg acaatacttt atacaagtag
      181 aaaaagactt caacagtcct gagaagatca tggcaagagc tttactcatg gctgatcaga
      241 aagtccacaa gctagaggct cagattgagg ctgaccgtcc taaagtgcta tttgccgacg
      301 cagtcagtgc tagtaagtca tcttgtctga ttggtgaact agctaaaatt ttgaaacaga
      361 atgggattga cattggtcaa aacaaacttt ttcaatggct acgctctaac ggctacctaa
      421 ttagtcgtcg tggagagtct tggaaccaac caacacaaaa aagcatgcag ttaggtctgt
      481 ttgaattaaa aaagacaaac atcaatcatg ctgacggtca tacaactgtc agtacaacta
      541 ctaaggtcac tggtaagggc caacagtgct ttatcaacaa gtttctcaat caggaatact
      601 tgacaggata aaaacaaaaa gcccctctgg aacggcaatt ccattgaggg actaagcaaa
      661 atactttacg aggtaattat atcatgaaaa cagtaaaaaa ggaatgggag ccacggattg
      721 taaacatcat ggcagatggc tctcaagttg acgatctgac aggatatgtc atccctgctg
      781 gtcattcgta ctatgacatc attttaggaa tgcacaagcg agagttacag aaaggggctt
      841 aaatatgagg tatgcagtat ataatcagga ataccaacga gaactacact cagatgaaca
      901 accactcagc tcaaaactca gaattgagct tgcaagctaa agggttgcta ttggtactga
      961 tgtctaataa ggatacatgg cgcccttaca ttgatgagct ttcaaaacgc tctaggaatg
     1021 ggcgtgacgc tcacagggca gcttttgacg agctgaaaga ggctggctat atccgtatct
     1081 atcgcaagag ctttggtcgt ggcaaa
//
LOCUS       DBERCW010000091         1049 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.091, whole genome shotgun sequence.
ACCESSION   DBERCW010000091 DBERCW010000000
VERSION     DBERCW010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.091"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..550
                     /locus_tag="ACL72M_002111"
     CDS             <1..550
                     /locus_tag="ACL72M_002111"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0717159.1"
                     /translation="ETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIISKVDLLFQKVSQLFE"
     gene            complement(498..>1049)
                     /locus_tag="ACL72M_002112"
     CDS             complement(498..>1049)
                     /locus_tag="ACL72M_002112"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0717160.1"
                     /translation="IPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQLWK"
BASE COUNT          376 a          165 c          152 g          356 t
ORIGIN      
        1 cgaaacaacc tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc
       61 tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg
      121 aactgaaata ccttgggtat ctatatcaga tatgcctata tctggttatg taactaatac
      181 gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg
      241 aactttatta atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc
      301 cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag
      361 agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat
      421 aaaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca
      481 tgaagagatg aaaagaatca tttccaaagt tgatttactt tttcaaaaag tttctcaact
      541 ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgcttagt
      601 gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt
      661 ttataaaata acggagagga caagttaaat aatagaaatt ttgaaataat ctctgaactt
      721 tcgaatggtg ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg
      781 attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta
      841 tgttttaaat aaacttgttc agaggagatg aattgtgtat caatgtagta atcattatcc
      901 aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaac acctttatta
      961 ttaatgctta aatcgccctt cttgtaagaa agacctgtat tcattgaaaa aatatctttt
     1021 atttttataa caacccaatt cataggtat
//
LOCUS       DBERCW010000092          966 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.092, whole genome shotgun sequence.
ACCESSION   DBERCW010000092 DBERCW010000000
VERSION     DBERCW010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..966
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.092"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..388
                     /locus_tag="ACL72M_002113"
     CDS             <1..388
                     /locus_tag="ACL72M_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717161.1"
                     /translation="YIRHLEDGKSLVDILKMMKTDRDAEIARKEQKEAQEKAKAERLE
                     EIAQSAKKNANANIKAYDAETGEILEQGTITPEPQNNAREVAKFEPSEPLVKLVRLEL
                     HGGLEQWENTQEYFEDNFIGFETLED"
     gene            410..586
                     /locus_tag="ACL72M_002114"
     CDS             410..586
                     /locus_tag="ACL72M_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717162.1"
                     /translation="MRCFYVSGKIADLDLGSEINAENSFMAAIEFVKRYTDLLKFGSN
                     EIKVSEVEEVQNDK"
     gene            576..>966
                     /gene="ssb"
                     /locus_tag="ACL72M_002115"
     CDS             576..>966
                     /gene="ssb"
                     /locus_tag="ACL72M_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017766998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGS0717163.1"
                     /translation="MINNVVLVGRLTRDAELRYTQSNIAVATFTLAVNRPFKNEAGER
                     EADFINCVIWRQSAENLANWAKKGSLIGVTGVIQTRSYDNQQGQRVYVTEVVASNFQL
                     LESRNSQQNNQGHQDHHGGYQQQGYSNQ"
BASE COUNT          328 a          158 c          230 g          250 t
ORIGIN      
        1 ctatatcaga catcttgaag atggtaagag ccttgttgat atcctcaaga tgatgaaaac
       61 tgaccgagat gctgagattg cacgcaaaga gcagaaagag gctcaagaaa aagcaaaagc
      121 tgaacgactt gaagaaattg ctcaatcggc caagaaaaat gctaatgcga atatcaaggc
      181 ttacgatgcc gaaacaggcg agattttgga acagggtaca attacaccag aacctcaaaa
      241 caatgcgcga gaggtggcaa aatttgagcc tagcgagcct ttggtcaaat tagtacgtct
      301 tgaattgcac ggtggtttag aacagtggga aaatacacaa gaatattttg aggataactt
      361 tatcggtttt gaaactttgg aggattaagt agaataagga gtcagaccta tgagatgttt
      421 ttatgtcagc ggtaaaattg cagatcttga tttggggtca gaaatcaatg cagaaaattc
      481 atttatggcc gctattgagt ttgtgaaacg atataccgac ttattaaagt ttggttcaaa
      541 tgaaatcaag gtatcagaag tagaggaggt gcaaaatgat aaataacgtt gttttagtag
      601 ggcgacttac aagagatgcc gaactgagat acacgcaatc taatattgcg gttgctacgt
      661 ttactcttgc tgtaaaccgt ccatttaaaa acgaggctgg agagcgtgag gctgatttta
      721 tcaattgcgt tatctggaga cagtcagctg aaaatcttgc taattgggct aaaaaaggct
      781 ctcttatcgg agttacagga gtaattcaaa cacgtagcta tgataaccag caaggtcaac
      841 gtgtttatgt cacagaagtt gttgccagta attttcaact gttggaaagt cgtaacagtc
      901 agcaaaataa tcaaggtcat caagaccatc atggcggtta tcagcagcag ggctacagta
      961 atcaag
//
LOCUS       DBERCW010000093          965 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.093, whole genome shotgun sequence.
ACCESSION   DBERCW010000093 DBERCW010000000
VERSION     DBERCW010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.093"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(370..768)
                     /locus_tag="ACL72M_002116"
     CDS             complement(370..768)
                     /locus_tag="ACL72M_002116"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0717164.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          303 a          189 c          140 g          333 t
ORIGIN      
        1 tcattatttc cattttcttt tggatttcac tctattctga aaaacttgtg tatatttact
       61 gaagctagca agtcttacct gtaaatttaa tgaaagcaac acaaaatccg agaggggaat
      121 ctcggattaa tagatagaga gtttttagtt taaataaatt gtttaaaata tcaacaacat
      181 cacttctttt cttaacctga taagtcttga ttcctaattt tggggctacg attatattgt
      241 cctcaatatc gtctagaaag acacaatttc taggttataa ctggtattta tcgatagtta
      301 ctcatataca tcagtccacc tccatactta tgtgcgagcc tctctttgta ttatacctcc
      361 atactcacct tacagattct tttggtaata atatctttgc ctaatgtaga gatagtcttg
      421 caaagaaaaa acttccttgt agccatgttt ctgataaaag tccggtgcct ggaactggta
      481 agtattgaca aaggcaaaac aacaatttcg attcttagct tcactttctg cctgttgcaa
      541 tagttttgaa ccgattcctt gccctcgcag ttcctctttt acaaacaaat actcgatttc
      601 tagccaattt ccaaaagtct ctgctatcaa acctgccagg agattgccct tttcatcttc
      661 gacataaaga ttaagtggct cactttcagc ctcttctctt tttgaacggt tataaacacg
      721 aatcagattc cctatttctt gcgatttatg tgattcctta ttttccaatc taaagtatag
      781 tgaaatgaaa taaaacatgc gcaaatcgat taaggaattt aatctaattt ctaacaatgt
      841 cttagaaatc aaagtgtact attttaactt caatgcacta tacatctaat actcaataaa
      901 aatcaaagag caaactagga aactagccgc aggttgctca aaacactgtt ttgaggttgt
      961 agata
//
LOCUS       DBERCW010000094          942 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.094, whole genome shotgun sequence.
ACCESSION   DBERCW010000094 DBERCW010000000
VERSION     DBERCW010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..942
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.094"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>942
                     /locus_tag="ACL72M_002117"
     CDS             <1..>942
                     /locus_tag="ACL72M_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGS0717165.1"
                     /translation="NGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSS
                     DREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLA
                     PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMT
                     HSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKV
                     PLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKY
                     YVEHPNERPHSDNGFGNASDHVRKNKADQDSKPDEDK"
BASE COUNT          312 a          186 c          208 g          236 t
ORIGIN      
        1 agaatggagt ttctcgttat atcccagcca aggatctttc agcagaaaca gcagcaggca
       61 ttgatagcaa actggccaag caggaaagtt tatcgcataa gctaggagct aagaaaactg
      121 acctcccatc tagtgataga gaattttaca ataagactta tgacttacta gcaagaattc
      181 accaagattt acttgataat aaaggtcgac aagttgattt tgaggctttg gataacctgt
      241 tggaacgact caaggatgtc tcaagtgata aagtcaagtt agtggatgat attcttgcct
      301 tcttagctcc gattcgtcat ccagaacgtt taggaaaacc aaatgcgcaa attacctaca
      361 ctgatgatga gattcaagta gccaagttgg caggcaagta cacaacagaa gacggttata
      421 tctttgatcc tcgtgatata accagtgatg agggggatgc ctatgtaact ccacatatga
      481 cccatagcca ctggattaaa aaagatagtt tgtctgaagc tgagagagcg gcagcccagg
      541 cttatgctaa agagaaaggt ttgacccctc cttcgacaga ccatcaggat tcaggaaata
      601 ctgaggcaaa aggagcagaa gctatctaca accgcgtgaa agcagctaag aaggtgccac
      661 ttgatcgtat gccttacaat cttcaatata ctgtagaagt caaaaacggt agtttaatca
      721 tacctcatta tgaccattac cataacatca aatttgagtg gtttgacgaa ggcctttatg
      781 aggcacctaa ggggtatact cttgaggatc ttttggcgac tgtcaagtac tatgtcgaac
      841 atccaaacga acgtccgcat tcagataatg gttttggtaa cgctagcgac catgttcgta
      901 aaaataaggc agaccaagac agtaaacctg atgaagataa gg
//
LOCUS       DBERCW010000095          934 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.095, whole genome shotgun sequence.
ACCESSION   DBERCW010000095 DBERCW010000000
VERSION     DBERCW010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..934
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.095"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>934
                     /locus_tag="ACL72M_002118"
     CDS             <1..>934
                     /locus_tag="ACL72M_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HGS0717166.1"
                     /translation="GQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTS
                     RICQEHDNQVYDRDKAVPGVNCPPMHPWCRSTTVAYDEDADYSKLKRRARNPVTGKTE
                     LVPADMTYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRI
                     AGENKLAGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTE
                     EYLKMKQKLVAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNG
                     SLHELYEKYRDTNTSDLERMKLFKEMLDLSNGLEI"
BASE COUNT          329 a          149 c          216 g          240 t
ORIGIN      
        1 aggtcagaat gatgcaaggc gtttggttcg gacggaatca gccttttttc ataaccaaat
       61 ggaactactc agctatgaag aagcagacat agaaaagtat atctttgtgg ccgtcttaga
      121 caagcgcaca tcacgcattt gtcaagaaca tgacaatcag gtctatgata gggataaggc
      181 tgtccctggt gtcaattgtc cacctatgca cccttggtgt aggtctacta ctgtcgcata
      241 cgacgaggac gcagactaca gcaagttgaa gcgcagagca aggaatccag tgacaggtaa
      301 gaccgagctg gtgcctgctg atatgactta taaagagtgg tatagcaagt atgttgcgaa
      361 agacggggaa aaggtgtata atcaagatac aagagaagcc aaggcgaaat tttatagcga
      421 acaactattg tccaaaattt caggagttga gccaaaaatt acaagtgata tgcaacgtat
      481 cgcaggagaa aacaaattgg caggtcttga atttaggaag aaaacagttg agtcgttatc
      541 acgtaaaatt attgcagata gcctagttga aaatataagt ttgtcaaaag ccgtgagtaa
      601 gattaatgac gccttaaggt acacaactat tttcgattcc gatactttta cagaagagta
      661 tttgaagatg aaacagaagc ttgtcgcaga aggttataaa attgtaaaag taaaaaacac
      721 ttggttagta gatggaccat acaaaggtgt gaatacagtc gttgaaaaag atggtatcaa
      781 ctttgaaatg cagtatcata ctcaggaaag tttcgactta aaaaatggtt cattacatga
      841 actctatgag aagtatcgtg atacgaatac atctgatcta gaacgcatga aattatttaa
      901 ggaaatgctt gatttaagca atgggcttga gatt
//
LOCUS       DBERCW010000096          910 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.096, whole genome shotgun sequence.
ACCESSION   DBERCW010000096 DBERCW010000000
VERSION     DBERCW010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.096"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..235
                     /locus_tag="ACL72M_002119"
     CDS             <1..235
                     /locus_tag="ACL72M_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717167.1"
                     /translation="KSKFAPQNGVATTILIGRDFDTGQVHANELKSTVPGQMYFDENG
                     EILTDIGQPVAEIEQQAETKPDIIDFNKKKVGN"
     gene            237..>910
                     /locus_tag="ACL72M_002120"
     CDS             237..>910
                     /locus_tag="ACL72M_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717168.1"
                     /translation="MTTENLKSALEYVVELNEHGLEILTAADGTEYYDANKFNLKELD
                     PKHYPKTLELSTLTSLVDYLKTDLNNLKNQRLIVAVEKNDEVCVWSENDEIEHRTLLV
                     DVKARIPELSFGRFLSLEQFNIMLQSNFIDDNDRGTLLEFASALKIENGAEIEDNGVS
                     QVATVKTGVASLAKGKAPNPVTLRPYRTFSEVEQPASLFVFRIDKQANMALFEADGKR
                     WVADAVG"
BASE COUNT          318 a          157 c          197 g          238 t
ORIGIN      
        1 gaaatcaaaa tttgcgcctc aaaatggagt agctacaaca attcttattg ggcgtgattt
       61 tgatacagga caagtacatg ctaatgagtt aaaaagtaca gtacctggtc aaatgtactt
      121 tgatgaaaac ggagaaattc tgacggatat tgggcaacca gtagcagaaa ttgaacaaca
      181 agcagaaaca aaaccagata ttattgattt caacaaaaag aaagtaggta actaatatga
      241 caacagaaaa tcttaaatca gcattggaat acgtagtaga actaaatgag catggtttgg
      301 aaattttaac agctgcagat ggaacagagt attatgatgc caacaaattc aacctcaaag
      361 aacttgaccc taaacactat cctaaaactc tggagctatc aaccttgaca agccttgttg
      421 actatctcaa aacagaccta aacaatttga aaaaccaacg cttgattgta gcagttgaga
      481 aaaacgatga ggtttgtgtg tggtctgaaa atgatgagat cgaacatcgc acattgcttg
      541 ttgatgttaa ggcacgcatc ccagagttat cttttggccg tttcctatca ttggaacagt
      601 tcaatatcat gttgcaatca aactttattg acgataacga tcgtggcaca ttgctagaat
      661 ttgctagcgc attgaaaatt gagaatgggg ctgaaattga agataatgga gtatctcaag
      721 tagcaacagt taaaacaggg gtggcaagcc ttgctaaagg caaagcacct aatccggtta
      781 cattgcgccc atatcgtaca tttagcgagg ttgagcaacc ggcaagccta tttgtcttta
      841 ggattgataa gcaagccaat atggctttat ttgaggcaga tggtaagcgt tgggtagctg
      901 atgcagtagg
//
LOCUS       DBERCW010000097          881 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.097, whole genome shotgun sequence.
ACCESSION   DBERCW010000097 DBERCW010000000
VERSION     DBERCW010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.097"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(8..81)
                     /locus_tag="ACL72M_002121"
     tRNA            complement(8..81)
                     /locus_tag="ACL72M_002121"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45..47),aa:Ile,seq:cat)
     gene            complement(95..168)
                     /locus_tag="ACL72M_002122"
     tRNA            complement(95..168)
                     /locus_tag="ACL72M_002122"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(132..134),aa:Met,seq:cat)
     gene            complement(174..247)
                     /locus_tag="ACL72M_002123"
     tRNA            complement(174..247)
                     /locus_tag="ACL72M_002123"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(211..213),aa:Pro,seq:tgg)
     gene            complement(263..336)
                     /locus_tag="ACL72M_002124"
     tRNA            complement(263..336)
                     /locus_tag="ACL72M_002124"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Arg,seq:acg)
     gene            complement(346..431)
                     /locus_tag="ACL72M_002125"
     tRNA            complement(346..431)
                     /locus_tag="ACL72M_002125"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Leu,seq:taa)
     gene            complement(439..510)
                     /locus_tag="ACL72M_002126"
     tRNA            complement(439..510)
                     /locus_tag="ACL72M_002126"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:gcc)
     gene            complement(533..605)
                     /locus_tag="ACL72M_002127"
     tRNA            complement(533..605)
                     /locus_tag="ACL72M_002127"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Thr,seq:tgt)
     gene            complement(624..705)
                     /locus_tag="ACL72M_002128"
     tRNA            complement(624..705)
                     /locus_tag="ACL72M_002128"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Leu,seq:tag)
     gene            complement(711..783)
                     /locus_tag="ACL72M_002129"
     tRNA            complement(711..783)
                     /locus_tag="ACL72M_002129"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(748..750),aa:Lys,seq:ttt)
     gene            complement(808..880)
                     /locus_tag="ACL72M_002130"
     tRNA            complement(808..880)
                     /locus_tag="ACL72M_002130"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(845..847),aa:Asp,seq:gtc)
BASE COUNT          232 a          256 c          199 g          194 t
ORIGIN      
        1 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
       61 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      121 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      181 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      241 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      301 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      361 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      421 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      481 ggtggtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      541 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      601 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      661 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      721 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga
      781 gtctaaaata acttgcgtta tcttaaacgg tcccgacggg aatcgaaccc gcgatcttcg
      841 ccgtgacagg gcgacgtgat aaccgctaca ctacgggacc t
//
LOCUS       DBERCW010000098          858 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.098, whole genome shotgun sequence.
ACCESSION   DBERCW010000098 DBERCW010000000
VERSION     DBERCW010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.098"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..858)
                     /locus_tag="ACL72M_002131"
                     /pseudo
     CDS             complement(1..858)
                     /locus_tag="ACL72M_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          263 a          155 c          175 g          265 t
ORIGIN      
        1 aggatgaacc tgcttaagat tgtcctcaat aagtccgaaa aatttctctg gttccttatt
       61 atagagctga tagtggtgtt tcaagtcttc tgaatagctc aaaagcttgt ttaaaatctc
      121 tttattggtt aagtacatac gaaaagtaga acgataaaat cgcttatcac tcagtttacg
      181 gctatcctgt tgaatgagtt tccagtagcg cttgatagcc ttgtattcat gagactttcg
      241 atgaaactga ttcatgattt ggacatgcac acgactcata gcacggctaa gatgttgtac
      301 aatatgaaag cgatcaagaa cgattttagc attcgggagt gaaacagtct gagagactgt
      361 ttcagcctga gcctagaaat ttgaaagcga agttgtctag ctaagtcata gtaaggacta
      421 aacatatcca tagtaatgat tttcacttga caacgaacgg ctctatcata tttaagaaag
      481 tgatctcgga tgatagcttg tgttctacct tcaagaacag tgatgatatt gagcttttca
      541 aaatcttgcg caataaagct catctccatc tcccgattga aacagtcact ccccggactg
      601 tttcaacgtc ccaagacata atctcaggca gatttctaaa attacactca aagtggaagt
      661 cattgagctt tcgaatgaca gttgaagttg agatggaaag ctgatgggca atatcggtca
      721 tagaaatctt ttcaattaac ttttgagcaa tcttttggtt gatgatacga gggatttggt
      781 gattcttctt gacgatagaa gtttcagcga ccatcatttt tgaacagtga tagcacttga
      841 atcgacgctt tctaagga
//
LOCUS       DBERCW010000099          800 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.099, whole genome shotgun sequence.
ACCESSION   DBERCW010000099 DBERCW010000000
VERSION     DBERCW010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.099"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>800
                     /locus_tag="ACL72M_002132"
     CDS             <1..>800
                     /locus_tag="ACL72M_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGS0717169.1"
                     /translation="YLRGRSITKLRDDLNEKYPKHVPWSYRAVRTILDNPVYCGFNQY
                     KGEIYPGNHEPIISKEEYDKTQSELKIRQRTAAENVNPRPFQAKYILSGIAQCGYCGA
                     PLKIMLGVKRKDGSRLKKYECHQRHPRTLRGVTTYNDNKKCDSGFYYKDKLEASVLKE
                     ISKLQDDADYLDKIFSGDNAETIDRESYKKQIEELSKKLSRLNDLYIDDRITLEELQS
                     KSAEFISMRATLETELENDSALRKNKRKADMRKLLNAEKVFSMDYEKQ"
BASE COUNT          301 a          143 c          178 g          178 t
ORIGIN      
        1 gttacctgag agggagatct attactaagt tgagagatga tctaaatgag aaatacccaa
       61 agcatgtgcc ttggagctat cgggcggtca gaaccatact cgataaccct gtctattgtg
      121 gtttcaatca gtataaggga gaaatttatc caggtaatca tgagccgatt atttcaaaag
      181 aggaatacga taagactcaa tctgagctaa aaataagaca aagaacagca gcagagaatg
      241 tcaatcctag accattccaa gctaagtaca ttttatccgg tatcgcccaa tgtggatatt
      301 gtggcgctcc tttaaaaatt atgttaggcg taaagaggaa agatgggagc aggttaaaaa
      361 aatatgaatg ccaccaaagg cacccacgaa cgctgagagg cgttactacc tacaacgaca
      421 ataaaaagtg tgactcagga ttttactaca aagacaagct agaggcctct gtgctaaaag
      481 aaataagcaa actacaagat gacgctgatt acctggacaa aatattttca ggagacaatg
      541 ctgagaccat agaccgtgag agctataaga aacaaataga ggagctatca aagaaactga
      601 gcagacttaa cgatctatac atagatgacc gcattaccct tgaagaatta cagagcaagt
      661 cagccgaatt tataagcatg agggctactc ttgagactga attggaaaac gattcagcgc
      721 tcaggaagaa caaaagaaag gctgatatga ggaaactgct aaacgctgaa aaagtgtttt
      781 caatggatta tgagaaacag
//
LOCUS       DBERCW010000100          786 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.100, whole genome shotgun sequence.
ACCESSION   DBERCW010000100 DBERCW010000000
VERSION     DBERCW010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.100"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            20..>786
                     /locus_tag="ACL72M_002133"
     CDS             20..>786
                     /locus_tag="ACL72M_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HGS0717170.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQF"
BASE COUNT          247 a          165 c          130 g          244 t
ORIGIN      
        1 actcattaga aagaatcata tggaacaatt acattttatc acaaaactgc tcgatattaa
       61 agacccaaac atcaagattc tagatatcat caatatggat acccacaaag aaattatcgc
      121 taagctggat tatgaggctc catcttgccc tgattgtgga agtctaatga agaaatatga
      181 ctttcaaaaa ccgtctaaga tcccttacct cgaaacaact ggtatgcctt ctagaattct
      241 ccttagaaaa cgccgtttca agtgctatca ctgttcaaaa atgatggttg ctgagactcc
      301 cctggtaaag aaaaatcacc aaatccctcg tatcatcaac caaaaaattg ctcaaaagtt
      361 aattgaaaaa atttctatga ctgatattgc ccatcagctg gccatttcaa cttcaactgt
      421 cattcgcaag ctcaatgact ttcactttga gcatgatttt tctcggcttc caaagattat
      481 gtcttgggat gagtatgcct tcactaaggg aaagatgagt ttcattgcgc aagattttga
      541 taatcttaat attatcactg ttcttgaagg cagaacacaa gctgtcatcc gaaatcactt
      601 tcttcgctac gatagagccg ttcgttgtca agtgaaaatc attacgatgg atatgtttag
      661 tccttactat gacttggcta aacagctttt tccgtgtgct aaaatcgttc tagatcgttt
      721 ccatattatc caacatctca gccgtgccat gagtcgtttt cgtgttcaaa ttatgaatca
      781 gtttga
//
LOCUS       DBERCW010000101          782 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.101, whole genome shotgun sequence.
ACCESSION   DBERCW010000101 DBERCW010000000
VERSION     DBERCW010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.101"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>782
                     /locus_tag="ACL72M_002134"
     CDS             <1..>782
                     /locus_tag="ACL72M_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HGS0717171.1"
                     /translation="AIRVGDYASRDIKEASFEYGYIKGDTYKPGGTCAGSGKITFTSI
                     ITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEIDRNRNTTTLELMDGMFKLNRE
                     YVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRYHIEQVPEGKKLSFRDMLSAM
                     TQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGLTKSEIEYQIAGITCKTDKKS
                     LTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPYNLNY"
BASE COUNT          223 a          156 c          190 g          213 t
ORIGIN      
        1 gctattcgtg ttggtgatta tgcttcacgg gatatcaaag aggctagttt tgagtatggc
       61 tacattaagg gcgatactta taagcctggt ggaacctgcg ctggtagcgg taaaattacc
      121 tttaccagta tcattaccac gttcaataag ctggataccc tgcaccctga gattggtcta
      181 ctggttgggg atacctacca gtgggtcaag atgggggaat acttcatcaa cgatattgag
      241 attgaccgaa accgaaacac taccacgctt gaacttatgg acggtatgtt taagctcaat
      301 cgtgagtacg tgacggactt gcatttccca gctgaagtac gagaggttat tcaggaaatc
      361 tgcctgaaaa caggcattga gttagcgaat gactatttcg gaatcagcgc gatgcgttat
      421 catattgagc aagttcctga gggcaagaaa ctttccttta gggatatgct gagcgctatg
      481 actcagatga ttgggatgtc ttgtttcttc aacagagaag gcaagatgga aatccgtgat
      541 ttgactgagt ccaatatcac gatcaacgct gacagttact tcttgcatgg cttgaccaag
      601 agtgagattg agtatcagat agctggtatc acttgtaaga cggacaagaa gtctctgacg
      661 gtcggtatga agacaggccg gtctttggaa ctggacaatg tcttcatgac ccagagcgct
      721 ttaaatgacc tgtattacaa actgaaaaac ctaacttact atccgtataa tctcaactac
      781 ca
//
LOCUS       DBERCW010000102          765 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.102, whole genome shotgun sequence.
ACCESSION   DBERCW010000102 DBERCW010000000
VERSION     DBERCW010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.102"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(139..>765)
                     /locus_tag="ACL72M_002135"
     CDS             complement(139..>765)
                     /locus_tag="ACL72M_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02391 family protein"
                     /protein_id="HGS0717172.1"
                     /translation="QDKSNIKLVIEYICNPLRYIDTVSDFENLRLKLNVVLSLKGLTI
                     SDDGHVVITTASQTLVEAKKRFESLEHMLRTLNVHPNVLKFCTQELLQENYFHAVFEA
                     SKGIFHRIRLLTGSSLDSASLIDQCFKTKEPIMIINGNKLQTLDEQSEYKGLKNLLLT
                     IAHLYRNSKAHKLKYYNPDSVHDALTALTLMSLAHNLLDNCTNTRRLD"
BASE COUNT          241 a          115 c          150 g          259 t
ORIGIN      
        1 cataaatcta tctttaggca aacagaatac ttatcagagc agttgactga aaggcttcat
       61 caccttgagg actacaatag tcccatagat gaagaaacaa ttagattagc tgaggtgact
      121 atagaatttt ataatctact aatcaagtct cctagtatta gtgcagttgt caaggagatt
      181 gtgagcgagg gacataagag ttaaggcagt taaggcatca tgaacgctat ctggattgta
      241 gtatttaagt ttatgtgctt tggaattacg ataaagatgt gcgattgtca gaagtaaatt
      301 cttcaatcct ttatattcac tttgttcgtc gagagtttgt aatttatttc cgttgataat
      361 catgatgggt tctttggttt taaaacattg gtctattaga cttgctgagt ccagagacga
      421 accggttagc aaacgaatgc ggtgaaagat tcctttactt gcttcaaata cagcatgaaa
      481 ataattttct tgtaagagtt cctgggtgca gaattttaaa acatttggat gaacatttaa
      541 tgttctcaac atatgttcaa gtgattcaaa tcgtttcttt gcctcaacta aagtttgtga
      601 agcagtagta ataactacat gtccgtcatc tgatatggta aggcctttta gggaaagaac
      661 gacatttagt tttaatctta agttttcaaa atctgaaacc gtatcgatgt acctcaaagg
      721 attgcagata tactcaatta caagtttgat atttgattta tcttg
//
LOCUS       DBERCW010000103          757 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.103, whole genome shotgun sequence.
ACCESSION   DBERCW010000103 DBERCW010000000
VERSION     DBERCW010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.103"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>757
                     /locus_tag="ACL72M_002136"
     CDS             <1..>757
                     /locus_tag="ACL72M_002136"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0717173.1"
                     /translation="TQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTSSID
                     RKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIAST
                     AFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQ
                     RIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVE
                     VLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDD"
BASE COUNT          298 a          109 c          119 g          231 t
ORIGIN      
        1 actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt gaggataaaa
       61 tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta tatagatacg
      121 tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata tctttcacct
      181 gaacaagcgc cttcccgtgc tagaaaatta gtttcgcaga atagtgtctt attttcaaca
      241 gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta tttgatagct
      301 agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa atattattta
      361 ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag ttatcctgca
      421 atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc cgaacaacaa
      481 cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc tgaaagttat
      541 aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc tattcttcaa
      601 tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt cgaagtttta
      661 cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat taaaaagaaa
      721 gatttggaca tttctattgt ttcccaagga gatgata
//
LOCUS       DBERCW010000104          729 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.104, whole genome shotgun sequence.
ACCESSION   DBERCW010000104 DBERCW010000000
VERSION     DBERCW010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.104"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>729
                     /locus_tag="ACL72M_002137"
     CDS             <1..>729
                     /locus_tag="ACL72M_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717174.1"
                     /translation="KLVSFAETIYLNTLYAKDFVVNSGKTIAQLGKTALELGKSALAW
                     TAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTSPITWIIAAIAALIAIGVL
                     LYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTKLQEIFEPIGQWFGEKFQQ
                     AWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQRWADVTSALANIGAWFTD
                     MFQKAWTGLTNIFSKLGSWFGERW"
BASE COUNT          202 a          132 c          181 g          214 t
ORIGIN      
        1 taagttggtc agttttgctg aaacaatcta tttgaacacc ttatatgcaa aagattttgt
       61 ggtcaattca ggtaaaacaa ttgcacagct aggaaaaact gctttagaac ttggtaaatc
      121 agctctagca tggactgctc atgcagcgaa aatgggatta gcaaccgcgg cggaatttgc
      181 acattctgtt gcagcaggag tcgctacagc tgcaacatgg gcttttaatg cagcgttagc
      241 agttttgaca agtccaataa catggattat tgcagcaatc gcagctttaa ttgctattgg
      301 tgttttgctc tatcaaaact gggacactgt tgttgagttt gctaaaactg catggcaagg
      361 actatgtgat tttatcagtg gtatttgtca agcgattggc gaatttttca gcggtctatg
      421 gacgaaacta caagaaatct ttgagccgat aggtcaatgg tttggcgaga aattccagca
      481 agcatgggac gccattgtaa acatattctc tggtatcgga gagtggttct ctggtgtatt
      541 ccaaggtgca tgggacgcta tcgttaatat cttcacacca atcggctcat ggttcggaca
      601 acgttgggca gatgtgacta gtgcgttggc taatatcggg gcatggttta ctgacatgtt
      661 ccaaaaagca tggactggct taacaaacat ctttagcaaa ctaggttctt ggtttggcga
      721 gagatggaa
//
LOCUS       DBERCW010000105          619 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.105, whole genome shotgun sequence.
ACCESSION   DBERCW010000105 DBERCW010000000
VERSION     DBERCW010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.105"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            49..261
                     /locus_tag="ACL72M_002138"
     CDS             49..261
                     /locus_tag="ACL72M_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717175.1"
                     /translation="MSDYKQRMIEEYKQLKERTNKLSLMISNYYVGTLDFKLKCPIEL
                     LETQHYTMCAYLKILEQRAEIENIEF"
     gene            272..>619
                     /locus_tag="ACL72M_002139"
     CDS             272..>619
                     /locus_tag="ACL72M_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717176.1"
                     /translation="MKFEFSLPRNTKLKSLNMVINSNDRQHQTDKAKVTKRIRAFAYW
                     HTSMNKDKGRAAFSPSNPCEVTVTIYSPTKSKLDPPNLYPTVKAIIDGMTDAGIWTDD
                     NHKVIKKLSFVYGG"
BASE COUNT          231 a          103 c          110 g          175 t
ORIGIN      
        1 cagaccaaaa acatatcaca gtattagcat aagaaagtgg aaattaaaat gagtgattac
       61 aaacaacgga tgattgaaga atacaaacaa ttaaaagagc gcaccaataa gttaagtttg
      121 atgattagta actattacgt aggaacactt gattttaaac taaaatgtcc tattgagtta
      181 cttgaaactc aacactatac aatgtgtgca tatctcaaga tccttgaaca gcgtgcagaa
      241 attgaaaaca ttgagtttta aggtaatcaa aatgaaattt gagttttctt tgcctcggaa
      301 tactaagcta aaatctctaa acatggttat caatagtaat gacagacaac atcaaacaga
      361 taaggctaaa gttactaaac gcattagagc ttttgcttat tggcatacat cgatgaacaa
      421 ggataaaggg agggctgctt ttagcccctc caacccttgt gaggttacag ttacaattta
      481 cagccctact aagtcaaaac ttgacccacc taatttatat ccaacagtca aggctatcat
      541 tgatggcatg actgatgcag gtatttggac agatgataat cataaggtta tcaaaaagtt
      601 atcctttgtt tatggtgga
//
LOCUS       DBERCW010000106          606 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.106, whole genome shotgun sequence.
ACCESSION   DBERCW010000106 DBERCW010000000
VERSION     DBERCW010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.106"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            21..383
                     /locus_tag="ACL72M_002140"
     CDS             21..383
                     /locus_tag="ACL72M_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGS0717177.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          207 a           71 c          111 g          217 t
ORIGIN      
        1 ttttcattga gtataacaca ttgttagaag ttggtttaaa tttcctaatc agtttgttca
       61 catttacctt cgatatatta tatcccatag ttaaggttgg tcatacagat gattatagcc
      121 atggagccgt aaaacttagt gtttctttag ttgacaaaga tgccatgaaa aaaatatctg
      181 taactgtaat aggatatttt gaaataaata tagatgaaaa tatcaccgat attctatacg
      241 taaatggtac tgctattctt tatccttatt tacgttctat tgtttcaata gtttcggcaa
      301 ttgatagcag tgaagcaatg ttgctaccta ccattaatgt tttagagtta ctagataaat
      361 ctcaaccttt tgaagaagaa taatttatta gctcactaaa ttgagggtaa ggaaaagtaa
      421 aagcagtaag aaaaatgtct tgcattatac agcaactttt tgggaatgag tagatggatt
      481 gaataaaatt tgattaagag tggatgattt atctgtagat tattattgga cagttagtct
      541 tgaagtagtc taagaattag gttataatca gtagaagcct tgctaataat gaggaggtta
      601 gtttat
//
LOCUS       DBERCW010000107          592 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.107, whole genome shotgun sequence.
ACCESSION   DBERCW010000107 DBERCW010000000
VERSION     DBERCW010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.107"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>592
                     /locus_tag="ACL72M_002141"
     CDS             <1..>592
                     /locus_tag="ACL72M_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HGS0717178.1"
                     /translation="AAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVS
                     EKLDELGITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVP
                     SKFLKGVNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYI
                     ITIADSKPAAKPSTQGKVVNRAKAWKTGTTYKEGDTV"
BASE COUNT          184 a          115 c          130 g          163 t
ORIGIN      
        1 gctgcagaag tagtcgctcc atatcttgat gaactacgtt ttggtgcagc acttggaaat
       61 gtaagtgaca atgttgccat gggtaaaaca gcaggagcga acaacgctta taatgcggtt
      121 cttgatgtgt ctgagaaact tgatgagctt ggaattacaa aagaacgctt gctcttcgtc
      181 actccaagtt tctacaaagc gatcaagtct gaaatcgttc gtctaccaca tggtgacgca
      241 gataagaaag tccttggaaa aggatatgtt ggtgaattgg atgattacac agtctataag
      301 gttccttcta aattcctgaa aggtgttaat gcccttgcta ctgctccagg tgttgttaca
      361 tctccagtac aagtagataa tactaagtac aacgataaca ttccagggcg atttggcgaa
      421 ttggtagagc aattgcttta cactggtgca tttgttcttg aacacttcaa gaaatacatc
      481 atcacaattg cagattctaa gcctgctgct aaaccatcta ctcaaggtaa agttgtaaac
      541 cgtgctaaag cgtggaaaac tggaacaacc tacaaagaag gtgacacagt ta
//
LOCUS       DBERCW010000108          587 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.108, whole genome shotgun sequence.
ACCESSION   DBERCW010000108 DBERCW010000000
VERSION     DBERCW010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.108"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(27..506)
                     /locus_tag="ACL72M_002142"
     CDS             complement(27..506)
                     /locus_tag="ACL72M_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGS0717179.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          149 a          137 c           76 g          225 t
ORIGIN      
        1 tttttcattt ttttttgcat gacttactag tgggtacgga tagtaaactc cttaaacaca
       61 atgcgtaagt ctcttaatac tctttgacgc cctcgaaatc gttcattgct taagacgcgt
      121 tctagttctt cttgtttctc tttactttgt ttgtttctat aatctcttag tgtttcatga
      181 aagagataat aatcatctag ccagagaccc ccctcactta tacgatgact gatctcaccc
      241 acttcttcat agggttcttt atcgtatcta cgcttctgac tttcctgctt acggatatag
      301 tctaaaattc gatttcgaaa cttggttttg aaatatttcc ttaaacgtgg aatatcgtct
      361 accagtcctt cttctctact aatcaattca tgtaagcaga gcatgccttc ttggtcccaa
      421 tccgataatt cccataaatg aaggtaatat tcatttctac acttatacac agtcccttgg
      481 acttcttcat acaattcttt aatcataatt ttcccctttc tagatacagt ctaacagatt
      541 agaaaacaca tttgttccat tttctccatt ctgttccctt tagctcc
//
LOCUS       DBERCW010000109          575 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.109, whole genome shotgun sequence.
ACCESSION   DBERCW010000109 DBERCW010000000
VERSION     DBERCW010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.109"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..575)
                     /locus_tag="ACL72M_002143"
                     /pseudo
     CDS             complement(1..575)
                     /locus_tag="ACL72M_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          176 a           99 c          126 g          174 t
ORIGIN      
        1 cttttcttta tctttgagga aggttttaaa gacagtctga aaaataggat gaacctgctt
       61 aagattgtcc tcgataagtc cgaaaaattt ctctggttcc ttattctgga agtgaaaaag
      121 caagagctga tagagctgat agtgatgttt caagtcttgt gaatagctca aaagtttgtc
      181 taaaatctct ttattggtta aatgcatacg aaaagtagga cgataaaatc gcttatcact
      241 cagtttacgg ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
      301 gaactttcga tccaattgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      361 atgttgcaca atgtgaaagc gatcaagaac gattttagca ttcgggagtg aaacagtctg
      421 ggagactgtt tcagcctgag cctagaaatt tgaaagcgaa gctgtttagc caagtcatag
      481 taagggctaa acatatccat agtaataatt ttgacgcgac atcggacagc tctatcgtag
      541 cgaagaaagt gatttcgaat gatagcttgt gttct
//
LOCUS       DBERCW010000110          547 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.110, whole genome shotgun sequence.
ACCESSION   DBERCW010000110 DBERCW010000000
VERSION     DBERCW010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.110"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..318
                     /locus_tag="ACL72M_002144"
     CDS             <1..318
                     /locus_tag="ACL72M_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-binding protein"
                     /protein_id="HGS0717180.1"
                     /translation="NTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADSKPAA
                     KKSAQGKTVNRAKAWKTGTAYKEGDTVTHEDKVYVAIKDITSSTNAPGSDSANWKEKT
                     GKK"
     gene            328..516
                     /locus_tag="ACL72M_002145"
     CDS             328..516
                     /locus_tag="ACL72M_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717181.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
BASE COUNT          193 a           99 c          119 g          136 t
ORIGIN      
        1 aatactaagt acaacgataa cattccaggt cgatttggtg aattggtaga gcaattactt
       61 tacactggtg catttgtgct tgaacacttc aaaaaataca tcatcacaat tgcagattct
      121 aagcctgctg ctaaaaaatc agcccaaggc aagacagtga accgtgctaa agcgtggaag
      181 actggaacag cctataaaga aggtgataca gtaacgcatg aagataaagt ctatgttgct
      241 atcaaagaca tcactagctc aaccaatgca ccaggctctg actcagctaa ctggaaagaa
      301 aaaactggta agaaataggt cttagttatg aaatttaaaa tcaaacaaga tttctatgat
      361 tgggaatcaa atgtgaaacg actggcagga gaggaacttg agattactga ggagcgctat
      421 gctgagctgg ctgacaatat tgccagcaac ggtgtcgcta tctcagatgt tcttgagaaa
      481 atcctccctg aacctgagtt cttagaagag gattgatatg tctatagagt tgctgaagaa
      541 attaaca
//
LOCUS       DBERCW010000111          514 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.111, whole genome shotgun sequence.
ACCESSION   DBERCW010000111 DBERCW010000000
VERSION     DBERCW010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.111"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            9..>514
                     /locus_tag="ACL72M_002146"
     CDS             9..>514
                     /locus_tag="ACL72M_002146"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0717182.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLV"
BASE COUNT          183 a           59 c          108 g          164 t
ORIGIN      
        1 gtggttgcat gaagaaagtg aaattagggc aagtggctac ttttatcaat ggctatgctt
       61 ttaaacctca agattggtca tctgaaggga aagagattat cagaatacag aatctgacta
      121 aaacttcaaa agggataaat tattattcgg gtacgattga taaaaaatac attgttgaag
      181 ctggtgatat tcttatttcg tggtcgggta cattaggggt ttttcagtgg tgtggaagat
      241 ccgcagtatt aaatcagcac atttttaaag tggtttttga taagatagat atagataaat
      301 cgtattttaa atatgttgtt gaaaaaggtt tacaagatgc tgtaaaacat actcatggtt
      361 ccacaatgaa acatttaact aaaaaatatt ttgataatat tatagttcca tatacaaatt
      421 tgggagagca acaaagaatt gcaagtgagc tggatttgtt aagcaagctg attttaagga
      481 gacaagaaca acttgaagag cttaatctac ttgt
//
LOCUS       DBERCW010000112          495 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.112, whole genome shotgun sequence.
ACCESSION   DBERCW010000112 DBERCW010000000
VERSION     DBERCW010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.112"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..>495)
                     /locus_tag="ACL72M_002147"
     CDS             complement(<1..>495)
                     /locus_tag="ACL72M_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0717183.1"
                     /translation="IRKLNDFHFKHDFSRLPEIMSWDEYAFTKGKMSFIAQDFEKLDI
                     ITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHI
                     VQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLT
                     NKEIF"
BASE COUNT          164 a           94 c           95 g          142 t
ORIGIN      
        1 aaaaatctct ttattggtta aatgcatacg aaaagtaggg cgataaaaat gtttatcgct
       61 gagtttacga ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
      121 agactttcga tccaattgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      181 atgttgtaca atgtgaaagc gatccaacac gattttagca cacgggaaaa gttgtctagc
      241 taagtcatag taaggactaa acatatccat agtaataatt ttgacgcgac atcggacaac
      301 tctatcgtag cgaagaaagt gatttcgaat gatagcttgt gttctaccct caagaacagt
      361 gatgatatcg agcttttcaa aatcttgcgc aatgaagctc atctttccct ttgtaaaagc
      421 atactcatcc caagacataa tctcaggaag acgcgaaaaa tcatgtttaa agtgaaaatc
      481 attgagctta cgaat
//
LOCUS       DBERCW010000113          453 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.114, whole genome shotgun sequence.
ACCESSION   DBERCW010000113 DBERCW010000000
VERSION     DBERCW010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.114"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>453
                     /locus_tag="ACL72M_002148"
     CDS             <1..>453
                     /locus_tag="ACL72M_002148"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0717184.1"
                     /translation="NEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAY
                     GGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLV
                     FLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVA"
BASE COUNT          160 a           65 c           82 g          146 t
ORIGIN      
        1 taacgagatg tttggggatc ctttaaataa taacaagaaa tttgcagtaa aaacgggaca
       61 acagtgtttt aaattttcaa gtggaaaatt tcttgataaa catgatagag tttttgaagg
      121 ttatcctgcc tatggtggaa atggcattgc ttggaaaagt cgaaaatatt taattgataa
      181 tcctactatc atcattggtc gtgtaggtgc atattgtggt aatgtaagaa ctacccacgg
      241 taaggtatgg ataagtgaca atgctatata tataaaagaa tttaagaatt ccgatttcaa
      301 tcttgtattt ttattagaat taatgaaagt aattgatttt agtaaatttg ctgatttctc
      361 aggtcaacca aagataactc aaaaaccatt agaaaatcag aaatatatcc tcccccctct
      421 agccctccaa aatgagttcg cagactttgt agc
//
LOCUS       DBERCW010000114          452 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.115, whole genome shotgun sequence.
ACCESSION   DBERCW010000114 DBERCW010000000
VERSION     DBERCW010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.115"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>452
                     /locus_tag="ACL72M_002149"
     CDS             <1..>452
                     /locus_tag="ACL72M_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717185.1"
                     /translation="VYIDFNPTDSRNPADYRWTRWKGRDGANGVAGRAGADGRTPYLH
                     IAYATSNNGSQGFSTTDSTNKTYIGTYTDYTQADSTDPKKYKWAKVKGDKGEKGDKGE
                     RGLQGLQGLQGARGEQGIPGPRGADGRTQYTHMAYADNATGGGFSQTNT"
BASE COUNT          159 a           92 c          115 g           86 t
ORIGIN      
        1 gtgtacattg attttaatcc aacagacagc agaaatcctg ctgattatcg ctggacaaga
       61 tggaaaggtc gtgatggcgc aaatggcgtg gcaggtaggg ctggtgcaga tggtaggaca
      121 ccatacttac acatagctta cgccacatca aataacggct cacaaggctt ctcaactact
      181 gacagtacaa ataaaacgta tatcggaaca tacacagatt acactcaggc agatagcaca
      241 gaccctaaaa aatacaagtg ggctaaagta aaaggggaca agggagaaaa aggcgataaa
      301 ggagaacgtg gattacaagg tttacaaggc ttgcaaggcg cacgaggtga acaaggtatt
      361 cctggaccta gaggggcaga tggtcgtaca caatatactc acatggccta tgccgataac
      421 gcaacaggtg gtggattcag tcaaacaaac ac
//
LOCUS       DBERCW010000115          423 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.116, whole genome shotgun sequence.
ACCESSION   DBERCW010000115 DBERCW010000000
VERSION     DBERCW010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.116"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>423
                     /locus_tag="ACL72M_002150"
     CDS             <1..>423
                     /locus_tag="ACL72M_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HGS0717186.1"
                     /translation="LQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKIL
                     HYHKQKFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNF
                     KPAGKSIEERPDVINLRLENGHYEIDTVLLTKIKNYCL"
BASE COUNT          154 a           73 c           83 g          113 t
ORIGIN      
        1 tttacaacaa gtgagaaaag ggctatacaa aaaggtctat tctgccgatt acgcacaaac
       61 tgtttaccaa ttcaatcgaa aacggtcggt gaaaaagtta attttaacaa aggaaatcag
      121 agagaagatc ttacactatc ataagcaaaa attttcgcct gaaatgatgg ttaacaagaa
      181 gcaagtgaaa gttggtattt caaccatcta ctactggttt cataatggtc atttaggatt
      241 gacgaaggcc gacatgcttt atcccagaaa aaggaaaggt gtcaagaagc aagctagtcc
      301 gaactttaag ccggcaggta aatctatcga agaacgtcct gacgttatta atcttcgctt
      361 ggaaaatggt cattatgaaa ttgataccgt cctactgact aagataaaaa attattgcct
      421 gtt
//
LOCUS       DBERCW010000116          390 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.117, whole genome shotgun sequence.
ACCESSION   DBERCW010000116 DBERCW010000000
VERSION     DBERCW010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.117"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..240
                     /locus_tag="ACL72M_002151"
     CDS             <1..240
                     /locus_tag="ACL72M_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0717187.1"
                     /translation="KIIDSYILSRMITNHVSLLLSNDAKIVELWEYAPELFVEEQQAV
                     EQERQRQALLLHKERMRDFAERHNRKRKEEVNGNS"
BASE COUNT          132 a           63 c          100 g           95 t
ORIGIN      
        1 aagattattg actcgtacat actttcgcga atgataacta atcatgtttc cttattactg
       61 tccaatgacg ctaagattgt tgagctttgg gaatatgcgc ctgagttgtt tgtagaagaa
      121 cagcaagcag tagaacagga acgacagaga caagcgcttt tgttgcataa ggaacggatg
      181 cgtgattttg cagagagaca taatcgaaaa aggaaggagg aagtaaatgg caactcttga
      241 tgaattgaag gtcatgattg acgctgagat agcgcctttc aggaaaaaga tgaaagaagt
      301 cgagaatcag gtcaaaggaa catctgacca agtgaaaaat gccactgcca aagttcgtga
      361 acagtcgaac tcaatcggta gtgcgtttgg
//
LOCUS       DBERCW010000117          380 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.118, whole genome shotgun sequence.
ACCESSION   DBERCW010000117 DBERCW010000000
VERSION     DBERCW010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.118"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..>380)
                     /locus_tag="ACL72M_002152"
     CDS             complement(<1..>380)
                     /locus_tag="ACL72M_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGS0717188.1"
                     /translation="LRTALKEDIYTFSHVPNLTDENFAGNTSGVAMEFKLMGLEMITK
                     TKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRGLPKNLLEISQIVNNLEGK
                     VTNRQLISLLPFVEDPDAELEALE"
BASE COUNT          108 a           89 c           75 g          108 t
ORIGIN      
        1 ttccaaggct tccagttcag cgtcagggtc ttccacaaac ggcaagagag aaataagctg
       61 tctattcgtc actttacctt caaggttgtt cacgatctga gagatttcta acaagttctt
      121 aggcaaacca cgactgaatt gtggaacgat tgaatgagac tctagtgcaa tctgtttcat
      181 acccaagtaa tgagcaaaaa tcgcaatacg ctgacgcaat cctcgcttat agttcgcttc
      241 cttggtctta gtaatcatct caaggcccat cagcttaaat tccatggcta cgcctgatgt
      301 attccctgcg aaattctcat cagtcaaatt aggcacatgg ctaaatgtgt agatgtcctc
      361 tttaagagct gtacgcaaga
//
LOCUS       DBERCW010000118          371 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.119, whole genome shotgun sequence.
ACCESSION   DBERCW010000118 DBERCW010000000
VERSION     DBERCW010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.119"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..>371)
                     /locus_tag="ACL72M_002153"
     CDS             complement(<1..>371)
                     /locus_tag="ACL72M_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0717189.1"
                     /translation="YWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKH
                     HYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYS
                     NAKLEATNNLIKLIKRNAFGFR"
BASE COUNT          107 a           50 c           87 g          127 t
ORIGIN      
        1 cgaaaaccaa aggcattgcg tttgataagt ttgatgagat tattggtcgc ttccaatttg
       61 gcgtttgaat agggtagttg aagggcgttg acgattttct ctttgttctt tagaaaggtt
      121 ttaaagacag tctgaaaaat aggatgaacc tgcttcagat tgtcctcaat gagtccgaaa
      181 aatttctcag ggtctttgtt ctgaaagtga aaaagtaaga gttgatagat ctgatagtgg
      241 tgtttcaagt cttctgaata gcttaaaatc ttgtcaagaa tttctttatt tgttaagtgc
      301 atgcgaaaag tagggcgata aaaacgttta tcgctgagtt tacgactatc ctgttggatg
      361 agtttccagt a
//
LOCUS       DBERCW010000119          358 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.120, whole genome shotgun sequence.
ACCESSION   DBERCW010000119 DBERCW010000000
VERSION     DBERCW010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.120"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>358
                     /locus_tag="ACL72M_002154"
     CDS             <1..>358
                     /locus_tag="ACL72M_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HGS0717190.1"
                     /translation="LGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADARRLAP
                     ARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEVSVTY
                     KSSPWYVHEDQINVGPY"
BASE COUNT          114 a           70 c           92 g           82 t
ORIGIN      
        1 ctaggggcag ataggcttat agctaaatgt agacgattgg ctagtaaaaa aactggcgag
       61 gatatcgtct tacgtgcggt acacaatgct actataaagg ttgtccaagc agatgcaaga
      121 agactcgcac cagcgagaga tggagagctt ataactagta tcaaaactag ggcaaaaatg
      181 gacggagata aggctatagg cgaggtttac accaatctta aatacgctcc ttacgttgag
      241 tttgggacag ggccaatagg acaagctagc cattcgggta tctctccaga ggtcagcgtc
      301 acttataagt ctagtccgtg gtatgtgcat gaagaccaaa tcaatgtagg accttacc
//
LOCUS       DBERCW010000120          345 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.121, whole genome shotgun sequence.
ACCESSION   DBERCW010000120 DBERCW010000000
VERSION     DBERCW010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.121"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            231..>345
                     /locus_tag="ACL72M_002155"
     CDS             231..>345
                     /locus_tag="ACL72M_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0717191.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLG"
BASE COUNT          118 a           53 c           78 g           96 t
ORIGIN      
        1 taccttagtc aagaattaga tgtttcacta tgtttgagta agttgatgat ttcatttgat
       61 aacaggtttg aaactgttag gctaggtggc caaggctaat catagccttg gtttagctga
      121 aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca
      181 cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag atgcaagaac
      241 attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt gagcggtgga
      301 agaatgaaaa taagtccaat cgtgaaattg caggcttgtt aggaa
//
LOCUS       DBERCW010000121          341 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.122, whole genome shotgun sequence.
ACCESSION   DBERCW010000121 DBERCW010000000
VERSION     DBERCW010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.122"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..>341)
                     /locus_tag="ACL72M_002156"
     CDS             complement(<1..>341)
                     /locus_tag="ACL72M_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HGS0717192.1"
                     /translation="YDAASAVVNKANVEFVGKWEFKANPTNAETYTPQVTEETIKVGQ
                     TPDLTDNVTNLPNLPAGTKVVDITPAGQIDTTKPGTYTGKVRVDYPDGSSTEVSVSVN
                     VLPAPETQTYK"
BASE COUNT           84 a           79 c           71 g          107 t
ORIGIN      
        1 ccttataggt ttgagtttct ggtgcaggca aaacattaac tgatacagac acctcagtag
       61 aagaaccatc tggatagtca actcgcacct tacctgtgta agtacctggt tttgttgtgt
      121 caatttgacc tgcaggtgta atatcaacta ccttagtgcc agctggaagg tttggcaagt
      181 tcgtcacatt atcggtcaag tcaggtgttt gtccaacctt gatagtttct tccgttacct
      241 gaggcgtata agtttccgca tttgtcggat tcgccttgaa ttcccactta cctacaaact
      301 ctacattagc cttgttaaca acggcgctag ctgcgtcata a
//
LOCUS       DBERCW010000122          330 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.123, whole genome shotgun sequence.
ACCESSION   DBERCW010000122 DBERCW010000000
VERSION     DBERCW010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.123"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(129..216)
                     /locus_tag="ACL72M_002157"
     tRNA            complement(129..216)
                     /locus_tag="ACL72M_002157"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Ser,seq:gct)
     gene            complement(223..296)
                     /locus_tag="ACL72M_002158"
     tRNA            complement(223..296)
                     /locus_tag="ACL72M_002158"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(260..262),aa:Ile,seq:gat)
BASE COUNT          101 a           83 c           59 g           87 t
ORIGIN      
        1 gaaatttgtc ctttctcgag cttagctttt cttcaaccca ctacagttga caaagagcct
       61 taagtttacg gatctgaagt tttattgtct ctaaaaacaa aaaagagagt tacaaactct
      121 cattaaaacg gagaataagg gattcgaacc cttgcgccag ttacccgacc taacgattta
      181 gcaaaccgtc ctcttcagcc tcttgagtaa ttctccaatt aatgggcacg agtggactcg
      241 aaccaccgac ctcacgctta tcaggcgtgc gctctaacca cctgagctac gcgcccaagt
      301 taaaaaactt ggtaatttga acaaagttca
//
LOCUS       DBERCW010000123          322 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 464111
            SAMN38107205-rid24759313.denovo.124, whole genome shotgun sequence.
ACCESSION   DBERCW010000123 DBERCW010000000
VERSION     DBERCW010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107205
            Sequence Read Archive: SRR26673606
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570828.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570828.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 09:07:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 58 of 135
            Pseudo Genes (internal stop)      :: 53 of 135
            Pseudo Genes (multiple problems)  :: 35 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107205-rid24759313.denovo.124"
                     /strain="GPSC16"
                     /isolate="464111"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..270
                     /locus_tag="ACL72M_002159"
                     /pseudo
     CDS             1..270
                     /locus_tag="ACL72M_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          122 a           57 c           54 g           89 t
ORIGIN      
        1 taaaatcttg gctgacagtg gttatcaagg gctcatgaag atatatcctc aagcacaaac
       61 ttcacgtaaa tccagcaaac tcaaaccgct aacaattgaa gataaagtct ataaccatgc
      121 gctatctaag gagagaagca aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat
      181 gatttcaaca acctatcgaa atcatctaaa cgcttcggat tacgaatgaa tttgattgct
      241 ggtattatca atcatgaact aggattctag ttttgcagga agtctattat caaaaatacc
      301 atcaagatta tataagattg at
//
